|Institutional Source||Beutler Lab|
|Gene Name||cilia and flagella associated protein 65|
|Is this an essential gene?||Possibly essential (E-score: 0.528)|
|Stock #||R5582 (G1)|
|Chromosomal Location||74902071-74935599 bp(-) (GRCm38)|
|Type of Mutation||intron|
|DNA Base Change (assembly)||G to A at 74907518 bp|
|Amino Acid Change|
|Ref Sequence||ENSEMBL: ENSMUSP00000092440 (fasta)|
|Gene Model||predicted gene model for transcript(s): [ENSMUST00000094844]|
|Predicted Effect||probably benign
|Predicted Effect||noncoding transcript
|Coding Region Coverage||
|Validation Efficiency||98% (61/62)|
|MGI Phenotype||FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] The protein encoded by this gene has putative coiled-coil domains and may be a transmembrane protein. The chicken ortholog of this gene is involved in the Rose-comb mutation, which is a large chromosome inversion, resulting in altered comb morphology and defects in sperm motility. [provided by RefSeq, Aug 2016]|
|Allele List at MGI|
|Other mutations in this stock||
|Other mutations in Cfap65||
(F):5'- TAGAGGATATGGAACTGCTGTCC -3'
(R):5'- CAGGTCAGCGTTCTGTCAAAG -3'
(F):5'- TATGGAACTGCTGTCCCACGAAG -3'
(R):5'- CAGCGTTCTGTCAAAGGTTCAAG -3'