Mutagenetix > Incidental Mutation

Incidental Mutation 'R5620:Prrc2c'

439759

Institutional Source

Beutler Lab

Gene Symbol

Prrc2c

Ensembl Gene

ENSMUSG00000040225

Gene Name

proline-rich coiled-coil 2C

Synonyms

9630039I18Rik, Bat2d, 1810043M20Rik, Bat2l2

MMRRC Submission

043160-MU

Accession Numbers

Essential gene?

Possibly non essential (E-score: 0.410) question?

Stock #

R5620 (G1)

Quality Score

225

Status

Not validated

Chromosome

Chromosomal Location

162499354-162568125 bp(-) (GRCm39)

Type of Mutation

missense

DNA Base Change (assembly)

T to C at 162501098 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Aspartic acid to Glycine at position 1235 (D1235G)

Ref Sequence

ENSEMBL: ENSMUSP00000138698 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000028016] [ENSMUST00000182149] [ENSMUST00000182393] [ENSMUST00000182593] [ENSMUST00000182660] [ENSMUST00000183223]

AlphaFold

no structure available at present

Predicted Effect

possibly damaging
Transcript: ENSMUST00000028016
AA Change: D2803G

PolyPhen 2 Score 0.883 (Sensitivity: 0.82; Specificity: 0.94)

SMART Domains

Protein: ENSMUSP00000028016
Gene: ENSMUSG00000040225
AA Change: D2803G

Domain	Start	End	E-Value	Type
Pfam:BAT2_N	1	164	7.7e-56	PFAM
internal_repeat_2	167	349	4.39e-5	PROSPERO
internal_repeat_1	336	391	2.14e-5	PROSPERO
low complexity region	407	414	N/A	INTRINSIC
SCOP:d1eq1a_	447	591	2e-5	SMART
low complexity region	649	669	N/A	INTRINSIC
low complexity region	733	745	N/A	INTRINSIC
coiled coil region	996	1026	N/A	INTRINSIC
low complexity region	1157	1186	N/A	INTRINSIC
low complexity region	1212	1222	N/A	INTRINSIC
internal_repeat_1	1240	1295	2.14e-5	PROSPERO
low complexity region	1308	1335	N/A	INTRINSIC
low complexity region	1388	1409	N/A	INTRINSIC
low complexity region	1715	1746	N/A	INTRINSIC
low complexity region	1765	1803	N/A	INTRINSIC
low complexity region	1815	1832	N/A	INTRINSIC
low complexity region	1844	1909	N/A	INTRINSIC
internal_repeat_2	1962	2148	4.39e-5	PROSPERO
low complexity region	2163	2177	N/A	INTRINSIC
low complexity region	2230	2252	N/A	INTRINSIC
low complexity region	2272	2286	N/A	INTRINSIC
low complexity region	2321	2338	N/A	INTRINSIC
low complexity region	2427	2438	N/A	INTRINSIC
low complexity region	2553	2576	N/A	INTRINSIC
low complexity region	2811	2828	N/A	INTRINSIC

Predicted Effect

probably benign
Transcript: ENSMUST00000182149

SMART Domains

Protein: ENSMUSP00000138548
Gene: ENSMUSG00000040225

Domain	Start	End	E-Value	Type
Pfam:BAT2_N	1	167	5.6e-73	PFAM
internal_repeat_1	336	391	1.49e-5	PROSPERO
low complexity region	407	414	N/A	INTRINSIC
SCOP:d1eq1a_	447	591	2e-5	SMART
low complexity region	649	669	N/A	INTRINSIC
low complexity region	733	745	N/A	INTRINSIC
internal_repeat_3	754	925	9.16e-5	PROSPERO
coiled coil region	996	1026	N/A	INTRINSIC
low complexity region	1157	1186	N/A	INTRINSIC
low complexity region	1212	1222	N/A	INTRINSIC
internal_repeat_1	1240	1295	1.49e-5	PROSPERO
low complexity region	1308	1335	N/A	INTRINSIC
low complexity region	1388	1409	N/A	INTRINSIC
low complexity region	1715	1746	N/A	INTRINSIC
low complexity region	1765	1803	N/A	INTRINSIC
low complexity region	1815	1832	N/A	INTRINSIC
low complexity region	1844	1909	N/A	INTRINSIC
internal_repeat_2	1962	2148	3.08e-5	PROSPERO
internal_repeat_3	1983	2153	9.16e-5	PROSPERO
low complexity region	2163	2177	N/A	INTRINSIC
low complexity region	2230	2252	N/A	INTRINSIC
low complexity region	2272	2286	N/A	INTRINSIC
low complexity region	2321	2338	N/A	INTRINSIC
low complexity region	2427	2438	N/A	INTRINSIC
low complexity region	2553	2576	N/A	INTRINSIC

Predicted Effect

probably benign
Transcript: ENSMUST00000182393

SMART Domains

Protein: ENSMUSP00000138451
Gene: ENSMUSG00000040225

Domain	Start	End	E-Value	Type
low complexity region	24	51	N/A	INTRINSIC
low complexity region	104	125	N/A	INTRINSIC
low complexity region	431	462	N/A	INTRINSIC
low complexity region	481	519	N/A	INTRINSIC
low complexity region	531	548	N/A	INTRINSIC
low complexity region	560	625	N/A	INTRINSIC
low complexity region	879	893	N/A	INTRINSIC
low complexity region	946	968	N/A	INTRINSIC
low complexity region	988	1002	N/A	INTRINSIC
low complexity region	1037	1054	N/A	INTRINSIC
low complexity region	1143	1154	N/A	INTRINSIC
low complexity region	1274	1297	N/A	INTRINSIC

Predicted Effect

probably damaging
Transcript: ENSMUST00000182593
AA Change: D2724G

PolyPhen 2 Score 0.991 (Sensitivity: 0.71; Specificity: 0.97)

SMART Domains

Protein: ENSMUSP00000138674
Gene: ENSMUSG00000040225
AA Change: D2724G

Domain	Start	End	E-Value	Type
Pfam:BAT2_N	1	165	4.1e-70	PFAM
internal_repeat_1	334	389	9.57e-6	PROSPERO
low complexity region	405	412	N/A	INTRINSIC
SCOP:d1eq1a_	445	589	3e-5	SMART
low complexity region	647	667	N/A	INTRINSIC
low complexity region	731	743	N/A	INTRINSIC
internal_repeat_3	752	923	6.11e-5	PROSPERO
coiled coil region	994	1024	N/A	INTRINSIC
low complexity region	1155	1184	N/A	INTRINSIC
low complexity region	1210	1220	N/A	INTRINSIC
internal_repeat_1	1238	1293	9.57e-6	PROSPERO
low complexity region	1306	1333	N/A	INTRINSIC
low complexity region	1386	1407	N/A	INTRINSIC
low complexity region	1713	1744	N/A	INTRINSIC
low complexity region	1763	1801	N/A	INTRINSIC
low complexity region	1813	1830	N/A	INTRINSIC
low complexity region	1842	1907	N/A	INTRINSIC
internal_repeat_2	1960	2146	2.01e-5	PROSPERO
internal_repeat_3	1981	2151	6.11e-5	PROSPERO
low complexity region	2161	2175	N/A	INTRINSIC
low complexity region	2228	2250	N/A	INTRINSIC
low complexity region	2270	2284	N/A	INTRINSIC
low complexity region	2319	2336	N/A	INTRINSIC
low complexity region	2425	2436	N/A	INTRINSIC
low complexity region	2551	2574	N/A	INTRINSIC
low complexity region	2671	2682	N/A	INTRINSIC
low complexity region	2730	2747	N/A	INTRINSIC

Predicted Effect

possibly damaging
Transcript: ENSMUST00000182660
AA Change: D2805G

PolyPhen 2 Score 0.942 (Sensitivity: 0.80; Specificity: 0.94)

SMART Domains

Protein: ENSMUSP00000138433
Gene: ENSMUSG00000040225
AA Change: D2805G

Domain	Start	End	E-Value	Type
Pfam:BAT2_N	1	167	7e-73	PFAM
internal_repeat_1	336	391	2.14e-5	PROSPERO
low complexity region	407	414	N/A	INTRINSIC
SCOP:d1eq1a_	447	591	2e-5	SMART
low complexity region	649	669	N/A	INTRINSIC
low complexity region	733	745	N/A	INTRINSIC
coiled coil region	996	1026	N/A	INTRINSIC
low complexity region	1157	1186	N/A	INTRINSIC
low complexity region	1212	1222	N/A	INTRINSIC
internal_repeat_1	1240	1295	2.14e-5	PROSPERO
low complexity region	1308	1335	N/A	INTRINSIC
low complexity region	1388	1409	N/A	INTRINSIC
low complexity region	1715	1746	N/A	INTRINSIC
low complexity region	1765	1803	N/A	INTRINSIC
low complexity region	1815	1832	N/A	INTRINSIC
low complexity region	1844	1909	N/A	INTRINSIC
internal_repeat_2	1962	2148	4.39e-5	PROSPERO
low complexity region	2163	2177	N/A	INTRINSIC
low complexity region	2230	2252	N/A	INTRINSIC
low complexity region	2272	2286	N/A	INTRINSIC
low complexity region	2321	2338	N/A	INTRINSIC
low complexity region	2427	2438	N/A	INTRINSIC
low complexity region	2553	2576	N/A	INTRINSIC
low complexity region	2811	2828	N/A	INTRINSIC

Predicted Effect

probably damaging
Transcript: ENSMUST00000183223
AA Change: D1235G

PolyPhen 2 Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)

SMART Domains

Protein: ENSMUSP00000138698
Gene: ENSMUSG00000040225
AA Change: D1235G

Domain	Start	End	E-Value	Type
low complexity region	289	320	N/A	INTRINSIC
low complexity region	339	377	N/A	INTRINSIC
low complexity region	389	406	N/A	INTRINSIC
low complexity region	418	483	N/A	INTRINSIC
low complexity region	739	761	N/A	INTRINSIC
low complexity region	781	795	N/A	INTRINSIC
low complexity region	830	847	N/A	INTRINSIC
low complexity region	936	947	N/A	INTRINSIC
low complexity region	1062	1085	N/A	INTRINSIC
low complexity region	1182	1193	N/A	INTRINSIC
low complexity region	1241	1258	N/A	INTRINSIC

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000184547

Coding Region Coverage

1x: 99.3%
3x: 98.7%
10x: 97.3%
20x: 95.4%

Validation Efficiency

Allele List at MGI

Other mutations in this stock

Total: 70 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
Aaas	A	C	15: 102,246,826 (GRCm39)	S511A	probably benign	Het
Abca3	C	T	17: 24,615,444 (GRCm39)	T845I	probably benign	Het
Acaa2	G	A	18: 74,938,945 (GRCm39)	A377T	possibly damaging	Het
Adcy4	C	A	14: 56,009,824 (GRCm39)	E743*	probably null	Het
Ahnak	T	A	19: 8,990,458 (GRCm39)	L3914*	probably null	Het
Akap1	G	T	11: 88,736,343 (GRCm39)	N106K	possibly damaging	Het
Arid2	C	T	15: 96,270,387 (GRCm39)	T1500I	probably benign	Het
Atp6v0a2	T	A	5: 124,783,909 (GRCm39)	Y252*	probably null	Het
C4bp	A	G	1: 130,581,090 (GRCm39)	S140P	probably damaging	Het
Cald1	A	G	6: 34,739,047 (GRCm39)	I384M	probably damaging	Het
Cdk12	A	G	11: 98,101,809 (GRCm39)	I556V	unknown	Het
Chmp2a	T	C	7: 12,766,237 (GRCm39)	S174G	probably benign	Het
Clybl	T	A	14: 122,548,755 (GRCm39)	N52K	probably damaging	Het
Cyp4a29	C	A	4: 115,108,088 (GRCm39)	S303R	probably benign	Het
Dab2	T	A	15: 6,447,796 (GRCm39)	D59E	probably damaging	Het
Dag1	C	A	9: 108,086,214 (GRCm39)	R309L	probably damaging	Het
Dync1i2	T	A	2: 71,088,483 (GRCm39)	M505K	probably benign	Het
Eif2b1	A	T	5: 124,717,075 (GRCm39)	M1K	probably null	Het
Epc1	A	G	18: 6,448,917 (GRCm39)	S577P	probably benign	Het
Eps8l1	T	A	7: 4,463,945 (GRCm39)	I23N	possibly damaging	Het
Etl4	A	G	2: 20,535,037 (GRCm39)	E164G	probably damaging	Het
Firrm	C	A	1: 163,789,613 (GRCm39)	G641*	probably null	Het
Gadl1	A	T	9: 115,766,230 (GRCm39)	M1L	probably benign	Het
Gda	T	C	19: 21,374,908 (GRCm39)	D336G	probably damaging	Het
Grm2	A	T	9: 106,527,645 (GRCm39)	V413D	probably damaging	Het
Hnrnpll	G	T	17: 80,346,051 (GRCm39)	N403K	probably damaging	Het
Ifit1	T	A	19: 34,625,238 (GRCm39)	F125I	probably damaging	Het
Igkv5-43	C	T	6: 69,800,892 (GRCm39)	V2I	probably benign	Het
Kat5	A	C	19: 5,659,507 (GRCm39)	Y44*	probably null	Het
Klc2	A	G	19: 5,162,884 (GRCm39)	V205A	probably damaging	Het
Klrb1c	T	A	6: 128,761,706 (GRCm39)	T133S	possibly damaging	Het
Krt20	A	G	11: 99,326,283 (GRCm39)	L157P	probably damaging	Het
Krt26	G	T	11: 99,228,597 (GRCm39)	T45N	possibly damaging	Het
Lama2	C	T	10: 26,866,876 (GRCm39)	D2873N	probably damaging	Het
Lig1	T	A	7: 13,020,532 (GRCm39)	C114S	possibly damaging	Het
Lonp1	G	C	17: 56,927,263 (GRCm39)	A330G	probably benign	Het
Maml2	A	T	9: 13,608,616 (GRCm39)	R21S	probably damaging	Het
Mrpl35	C	T	6: 71,794,720 (GRCm39)	V83I	probably benign	Het
Myo3b	A	G	2: 70,069,254 (GRCm39)	R498G	probably benign	Het
Nup153	C	A	13: 46,837,482 (GRCm39)	E1247*	probably null	Het
Or2t48	A	T	11: 58,420,557 (GRCm39)	M85K	probably damaging	Het
Pcdhac2	A	G	18: 37,277,257 (GRCm39)	N79S	probably benign	Het
Pcgf6	C	T	19: 47,036,406 (GRCm39)	G221D	probably damaging	Het
Phf11b	C	T	14: 59,558,953 (GRCm39)	D260N	probably benign	Het
Pla2g5	T	C	4: 138,531,921 (GRCm39)	M28V	possibly damaging	Het
Prpf8	T	C	11: 75,395,927 (GRCm39)	S1934P	possibly damaging	Het
Prr5	A	G	15: 84,640,570 (GRCm39)	S140G	probably benign	Het
Rasgrp2	T	C	19: 6,455,031 (GRCm39)	S254P	probably damaging	Het
Rassf8	C	T	6: 145,765,907 (GRCm39)		probably benign	Het
Rgs20	T	A	1: 4,982,666 (GRCm39)	E167D	probably damaging	Het
Rmnd1	G	T	10: 4,372,159 (GRCm39)	A180E	probably damaging	Het
Rnf103	A	G	6: 71,486,992 (GRCm39)	D541G	probably benign	Het
Rpl9	G	T	5: 65,546,468 (GRCm39)	Q140K	probably benign	Het
Sfmbt1	T	G	14: 30,506,148 (GRCm39)		probably null	Het
Shank1	C	A	7: 43,962,160 (GRCm39)	D10E	unknown	Het
Srrm4	G	T	5: 116,587,672 (GRCm39)		probably benign	Het
Sucla2	T	A	14: 73,832,836 (GRCm39)	V447E	probably damaging	Het
Tbc1d1	A	G	5: 64,331,055 (GRCm39)	D78G	probably benign	Het
Tcp1	T	A	17: 13,138,224 (GRCm39)		probably null	Het
Tctn3	C	A	19: 40,597,361 (GRCm39)	E230*	probably null	Het
Thsd7b	G	A	1: 130,090,673 (GRCm39)		probably null	Het
Tmem63a	A	G	1: 180,797,811 (GRCm39)	M621V	probably benign	Het
Tnxb	A	T	17: 34,936,504 (GRCm39)	K2756*	probably null	Het
Trpm8	G	A	1: 88,287,373 (GRCm39)		probably null	Het
Txndc16	C	A	14: 45,373,335 (GRCm39)	V764F	possibly damaging	Het
Ush2a	A	T	1: 188,492,020 (GRCm39)	D3103V	possibly damaging	Het
Usp22	A	T	11: 61,049,206 (GRCm39)	I381N	probably damaging	Het
Zfp462	T	A	4: 55,013,464 (GRCm39)	M1810K	probably benign	Het
Zfp64	T	A	2: 168,741,888 (GRCm39)	M347L	possibly damaging	Het
Zfp69	T	C	4: 120,787,719 (GRCm39)	D532G	probably damaging	Het

Other mutations in Prrc2c

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00425:Prrc2c	APN	1	162,548,182 (GRCm39)	splice site	probably null
IGL00577:Prrc2c	APN	1	162,525,685 (GRCm39)	missense	unknown
IGL00580:Prrc2c	APN	1	162,525,685 (GRCm39)	missense	unknown
IGL01295:Prrc2c	APN	1	162,510,061 (GRCm39)	missense	probably damaging	1.00
IGL01554:Prrc2c	APN	1	162,538,355 (GRCm39)	missense	probably damaging	0.99
IGL01684:Prrc2c	APN	1	162,534,031 (GRCm39)	unclassified	probably benign
IGL01745:Prrc2c	APN	1	162,552,297 (GRCm39)	missense	probably damaging	1.00
IGL01770:Prrc2c	APN	1	162,532,068 (GRCm39)	missense	probably benign	0.23
IGL01905:Prrc2c	APN	1	162,532,898 (GRCm39)	unclassified	probably benign
IGL02304:Prrc2c	APN	1	162,511,705 (GRCm39)	missense	probably benign	0.05
IGL02389:Prrc2c	APN	1	162,520,439 (GRCm39)	missense	probably damaging	1.00
IGL02540:Prrc2c	APN	1	162,550,706 (GRCm39)	missense	probably damaging	1.00
IGL02681:Prrc2c	APN	1	162,533,181 (GRCm39)	unclassified	probably benign
IGL02686:Prrc2c	APN	1	162,535,516 (GRCm39)	unclassified	probably benign
IGL02795:Prrc2c	APN	1	162,541,868 (GRCm39)	missense	probably benign
IGL02894:Prrc2c	APN	1	162,505,626 (GRCm39)	missense	probably damaging	1.00
IGL02957:Prrc2c	APN	1	162,534,104 (GRCm39)	unclassified	probably benign
IGL02981:Prrc2c	APN	1	162,532,748 (GRCm39)	unclassified	probably benign
IGL03070:Prrc2c	APN	1	162,504,978 (GRCm39)	missense	probably damaging	1.00
IGL03096:Prrc2c	APN	1	162,529,928 (GRCm39)	missense	unknown
R0058:Prrc2c	UTSW	1	162,526,453 (GRCm39)	missense	unknown
R0058:Prrc2c	UTSW	1	162,526,453 (GRCm39)	missense	unknown
R0135:Prrc2c	UTSW	1	162,543,052 (GRCm39)	splice site	probably benign
R0279:Prrc2c	UTSW	1	162,543,033 (GRCm39)	missense	probably damaging	1.00
R0363:Prrc2c	UTSW	1	162,525,380 (GRCm39)	missense	unknown
R0436:Prrc2c	UTSW	1	162,532,883 (GRCm39)	unclassified	probably benign
R0605:Prrc2c	UTSW	1	162,509,995 (GRCm39)	missense	probably damaging	1.00
R0696:Prrc2c	UTSW	1	162,536,421 (GRCm39)	critical splice donor site	probably null
R0981:Prrc2c	UTSW	1	162,533,550 (GRCm39)	unclassified	probably benign
R1693:Prrc2c	UTSW	1	162,546,282 (GRCm39)	missense	probably damaging	0.98
R1714:Prrc2c	UTSW	1	162,504,945 (GRCm39)	missense	probably damaging	1.00
R1791:Prrc2c	UTSW	1	162,532,551 (GRCm39)	unclassified	probably benign
R1794:Prrc2c	UTSW	1	162,533,528 (GRCm39)	unclassified	probably benign
R1998:Prrc2c	UTSW	1	162,532,487 (GRCm39)	unclassified	probably benign
R2040:Prrc2c	UTSW	1	162,525,126 (GRCm39)	missense	probably damaging	1.00
R2168:Prrc2c	UTSW	1	162,537,903 (GRCm39)	unclassified	probably benign
R2246:Prrc2c	UTSW	1	162,535,360 (GRCm39)	unclassified	probably benign
R2830:Prrc2c	UTSW	1	162,536,485 (GRCm39)	unclassified	probably benign
R2926:Prrc2c	UTSW	1	162,533,696 (GRCm39)	unclassified	probably benign
R3703:Prrc2c	UTSW	1	162,538,260 (GRCm39)	missense	probably damaging	1.00
R3745:Prrc2c	UTSW	1	162,525,754 (GRCm39)	missense	unknown
R3760:Prrc2c	UTSW	1	162,520,420 (GRCm39)	missense	probably damaging	1.00
R3784:Prrc2c	UTSW	1	162,537,238 (GRCm39)	unclassified	probably benign
R3959:Prrc2c	UTSW	1	162,536,461 (GRCm39)	unclassified	probably benign
R4255:Prrc2c	UTSW	1	162,533,895 (GRCm39)	unclassified	probably benign
R4276:Prrc2c	UTSW	1	162,501,160 (GRCm39)	missense	probably damaging	1.00
R4421:Prrc2c	UTSW	1	162,536,630 (GRCm39)	unclassified	probably benign
R4593:Prrc2c	UTSW	1	162,525,101 (GRCm39)	missense	probably damaging	1.00
R4651:Prrc2c	UTSW	1	162,550,843 (GRCm39)	missense	probably damaging	1.00
R4652:Prrc2c	UTSW	1	162,550,843 (GRCm39)	missense	probably damaging	1.00
R4660:Prrc2c	UTSW	1	162,508,464 (GRCm39)	missense	probably damaging	1.00
R4677:Prrc2c	UTSW	1	162,532,748 (GRCm39)	unclassified	probably benign
R4688:Prrc2c	UTSW	1	162,525,256 (GRCm39)	missense	unknown
R4753:Prrc2c	UTSW	1	162,518,799 (GRCm39)	missense	probably damaging	1.00
R4790:Prrc2c	UTSW	1	162,538,050 (GRCm39)	missense	unknown
R4981:Prrc2c	UTSW	1	162,520,116 (GRCm39)	missense	probably damaging	1.00
R4995:Prrc2c	UTSW	1	162,532,879 (GRCm39)	unclassified	probably benign
R5119:Prrc2c	UTSW	1	162,533,009 (GRCm39)	unclassified	probably benign
R5127:Prrc2c	UTSW	1	162,525,415 (GRCm39)	missense	unknown
R5291:Prrc2c	UTSW	1	162,533,151 (GRCm39)	unclassified	probably benign
R5474:Prrc2c	UTSW	1	162,537,213 (GRCm39)	unclassified	probably benign
R5543:Prrc2c	UTSW	1	162,501,080 (GRCm39)	missense	probably damaging	0.99
R5579:Prrc2c	UTSW	1	162,508,327 (GRCm39)	critical splice donor site	probably null
R5594:Prrc2c	UTSW	1	162,526,600 (GRCm39)	missense	unknown
R5994:Prrc2c	UTSW	1	162,501,725 (GRCm39)	splice site	probably null
R6142:Prrc2c	UTSW	1	162,537,956 (GRCm39)	missense	unknown
R6199:Prrc2c	UTSW	1	162,510,085 (GRCm39)	missense	probably damaging	1.00
R6277:Prrc2c	UTSW	1	162,541,883 (GRCm39)	missense	probably benign
R6504:Prrc2c	UTSW	1	162,525,364 (GRCm39)	missense	unknown
R6671:Prrc2c	UTSW	1	162,525,154 (GRCm39)	missense	probably damaging	1.00
R6785:Prrc2c	UTSW	1	162,536,670 (GRCm39)	unclassified	probably benign
R6799:Prrc2c	UTSW	1	162,536,630 (GRCm39)	unclassified	probably benign
R6801:Prrc2c	UTSW	1	162,536,630 (GRCm39)	unclassified	probably benign
R6850:Prrc2c	UTSW	1	162,536,630 (GRCm39)	unclassified	probably benign
R6851:Prrc2c	UTSW	1	162,536,630 (GRCm39)	unclassified	probably benign
R6856:Prrc2c	UTSW	1	162,509,940 (GRCm39)	missense	probably damaging	1.00
R6869:Prrc2c	UTSW	1	162,536,630 (GRCm39)	unclassified	probably benign
R6882:Prrc2c	UTSW	1	162,536,630 (GRCm39)	unclassified	probably benign
R6884:Prrc2c	UTSW	1	162,536,630 (GRCm39)	unclassified	probably benign
R6897:Prrc2c	UTSW	1	162,533,075 (GRCm39)	unclassified	probably benign
R6934:Prrc2c	UTSW	1	162,548,074 (GRCm39)	missense	probably benign	0.10
R6976:Prrc2c	UTSW	1	162,520,413 (GRCm39)	missense	probably damaging	1.00
R7132:Prrc2c	UTSW	1	162,508,850 (GRCm39)	missense	possibly damaging	0.77
R7165:Prrc2c	UTSW	1	162,501,086 (GRCm39)	missense	possibly damaging	0.94
R7282:Prrc2c	UTSW	1	162,507,543 (GRCm39)	missense	possibly damaging	0.59
R7467:Prrc2c	UTSW	1	162,504,932 (GRCm39)	missense	possibly damaging	0.84
R7915:Prrc2c	UTSW	1	162,519,977 (GRCm39)	missense	probably benign	0.39
R8068:Prrc2c	UTSW	1	162,536,630 (GRCm39)	unclassified	probably benign
R8529:Prrc2c	UTSW	1	162,536,663 (GRCm39)	unclassified	probably benign
R8734:Prrc2c	UTSW	1	162,507,081 (GRCm39)	missense	possibly damaging	0.92
R8735:Prrc2c	UTSW	1	162,537,127 (GRCm39)	missense	unknown
R8813:Prrc2c	UTSW	1	162,532,812 (GRCm39)	missense	unknown
R8946:Prrc2c	UTSW	1	162,536,478 (GRCm39)	unclassified	probably benign
R8975:Prrc2c	UTSW	1	162,533,630 (GRCm39)	missense	unknown
R9035:Prrc2c	UTSW	1	162,503,295 (GRCm39)	missense	possibly damaging	0.96
R9185:Prrc2c	UTSW	1	162,532,212 (GRCm39)	missense	unknown
R9261:Prrc2c	UTSW	1	162,505,622 (GRCm39)	missense	possibly damaging	0.48
R9287:Prrc2c	UTSW	1	162,541,843 (GRCm39)	missense	probably benign	0.34
R9289:Prrc2c	UTSW	1	162,507,130 (GRCm39)	missense	probably benign	0.33
R9466:Prrc2c	UTSW	1	162,503,258 (GRCm39)	missense	possibly damaging	0.53
R9523:Prrc2c	UTSW	1	162,525,298 (GRCm39)	missense	unknown
R9542:Prrc2c	UTSW	1	162,508,359 (GRCm39)	missense	possibly damaging	0.88
R9629:Prrc2c	UTSW	1	162,519,959 (GRCm39)	missense	possibly damaging	0.95
R9744:Prrc2c	UTSW	1	162,505,733 (GRCm39)	missense	possibly damaging	0.96
R9748:Prrc2c	UTSW	1	162,535,435 (GRCm39)	missense	unknown
X0020:Prrc2c	UTSW	1	162,535,416 (GRCm39)	unclassified	probably benign
X0039:Prrc2c	UTSW	1	162,532,362 (GRCm39)	frame shift	probably null

Predicted Primers

PCR Primer
(F):5'- ACAGACCACTTTACCCCTGTG -3'
(R):5'- GAACTGAGATTGATTTGACAGGC -3'

Sequencing Primer
(F):5'- GGCTGGCATTATTTGACTTCAC -3'
(R):5'- ACAGGCTTTGGTAATGTTAGGTAATG -3'

Posted On

2016-11-08