Incidental Mutation 'R5636:Spag9'
| ID |
440384 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Spag9
|
| Ensembl Gene |
ENSMUSG00000020859 |
| Gene Name |
sperm associated antigen 9 |
| Synonyms |
syd1, JIP4, Mapk8ip4, 4733401I23Rik, JLP, 3110018C07Rik, 4831406C20Rik |
| MMRRC Submission |
043287-MU
|
| Accession Numbers |
|
| Essential gene? |
Probably essential
(E-score: 0.785)
|
| Stock # |
R5636 (G1)
|
| Quality Score |
225 |
|
Status
|
Not validated
|
| Chromosome |
11 |
| Chromosomal Location |
93996091-94126085 bp(+) (GRCm38) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
C to A
at 94069012 bp (GRCm38)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Aspartic acid to Glutamic Acid
at position 342
(D342E)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000042271
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000024979]
[ENSMUST00000041956]
[ENSMUST00000075695]
[ENSMUST00000092777]
[ENSMUST00000103168]
[ENSMUST00000132079]
|
| AlphaFold |
no structure available at present |
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000024979
AA Change: D199E
PolyPhen 2
Score 0.781 (Sensitivity: 0.85; Specificity: 0.93)
|
| SMART Domains |
Protein: ENSMUSP00000024979
Gene: ENSMUSG00000020859
AA Change: D199E
| Domain | Start | End | E-Value | Type |
|---|
|
transmembrane domain
|
7 |
29 |
N/A |
INTRINSIC |
|
PDB:2W83|D
|
253 |
305 |
1e-25 |
PDB |
|
low complexity region
|
306 |
339 |
N/A |
INTRINSIC |
|
coiled coil region
|
572 |
606 |
N/A |
INTRINSIC |
|
low complexity region
|
735 |
751 |
N/A |
INTRINSIC |
|
SCOP:d1kb0a2
|
823 |
969 |
3e-5 |
SMART |
|
Blast:WD40
|
924 |
964 |
8e-18 |
BLAST |
|
low complexity region
|
1132 |
1150 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000041956
AA Change: D342E
PolyPhen 2
Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)
|
| SMART Domains |
Protein: ENSMUSP00000042271
Gene: ENSMUSG00000020859
AA Change: D342E
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:Jnk-SapK_ap_N
|
24 |
179 |
2e-61 |
PFAM |
|
Pfam:JIP_LZII
|
390 |
460 |
5.3e-32 |
PFAM |
|
coiled coil region
|
710 |
744 |
N/A |
INTRINSIC |
|
low complexity region
|
873 |
889 |
N/A |
INTRINSIC |
|
SCOP:d1kb0a2
|
961 |
1107 |
1e-5 |
SMART |
|
Blast:WD40
|
1062 |
1102 |
1e-17 |
BLAST |
|
low complexity region
|
1270 |
1288 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000075695
AA Change: D199E
PolyPhen 2
Score 0.036 (Sensitivity: 0.94; Specificity: 0.82)
|
| SMART Domains |
Protein: ENSMUSP00000075115
Gene: ENSMUSG00000020859
AA Change: D199E
| Domain | Start | End | E-Value | Type |
|---|
|
transmembrane domain
|
7 |
29 |
N/A |
INTRINSIC |
|
PDB:2W83|D
|
253 |
305 |
1e-25 |
PDB |
|
low complexity region
|
306 |
339 |
N/A |
INTRINSIC |
|
coiled coil region
|
571 |
605 |
N/A |
INTRINSIC |
|
low complexity region
|
734 |
750 |
N/A |
INTRINSIC |
|
SCOP:d1kb0a2
|
822 |
968 |
3e-5 |
SMART |
|
Blast:WD40
|
923 |
963 |
7e-18 |
BLAST |
|
low complexity region
|
1131 |
1149 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000092777
AA Change: D199E
PolyPhen 2
Score 0.238 (Sensitivity: 0.91; Specificity: 0.88)
|
| SMART Domains |
Protein: ENSMUSP00000090452
Gene: ENSMUSG00000020859
AA Change: D199E
| Domain | Start | End | E-Value | Type |
|---|
|
transmembrane domain
|
7 |
29 |
N/A |
INTRINSIC |
|
PDB:2W83|D
|
254 |
306 |
1e-25 |
PDB |
|
low complexity region
|
307 |
340 |
N/A |
INTRINSIC |
|
coiled coil region
|
572 |
606 |
N/A |
INTRINSIC |
|
low complexity region
|
735 |
751 |
N/A |
INTRINSIC |
|
SCOP:d1kb0a2
|
823 |
969 |
3e-5 |
SMART |
|
Blast:WD40
|
924 |
964 |
7e-18 |
BLAST |
|
low complexity region
|
1132 |
1150 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000103168
AA Change: D199E
PolyPhen 2
Score 0.238 (Sensitivity: 0.91; Specificity: 0.88)
|
| SMART Domains |
Protein: ENSMUSP00000099457
Gene: ENSMUSG00000020859
AA Change: D199E
| Domain | Start | End | E-Value | Type |
|---|
|
transmembrane domain
|
7 |
29 |
N/A |
INTRINSIC |
|
PDB:2W83|D
|
249 |
301 |
1e-25 |
PDB |
|
low complexity region
|
302 |
335 |
N/A |
INTRINSIC |
|
coiled coil region
|
567 |
601 |
N/A |
INTRINSIC |
|
low complexity region
|
730 |
746 |
N/A |
INTRINSIC |
|
SCOP:d1kb0a2
|
818 |
964 |
3e-5 |
SMART |
|
Blast:WD40
|
919 |
959 |
8e-18 |
BLAST |
|
low complexity region
|
1127 |
1145 |
N/A |
INTRINSIC |
|
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000132079
AA Change: D199E
PolyPhen 2
Score 0.893 (Sensitivity: 0.82; Specificity: 0.94)
|
| SMART Domains |
Protein: ENSMUSP00000118850
Gene: ENSMUSG00000020859
AA Change: D199E
| Domain | Start | End | E-Value | Type |
|---|
|
transmembrane domain
|
7 |
29 |
N/A |
INTRINSIC |
|
coiled coil region
|
360 |
394 |
N/A |
INTRINSIC |
|
low complexity region
|
523 |
539 |
N/A |
INTRINSIC |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000138154
|
| Predicted Effect |
unknown
Transcript: ENSMUST00000156019
AA Change: D191E
|
| SMART Domains |
Protein: ENSMUSP00000115864
Gene: ENSMUSG00000020859
AA Change: D191E
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:JIP_LZII
|
240 |
310 |
1.1e-32 |
PFAM |
|
coiled coil region
|
559 |
593 |
N/A |
INTRINSIC |
|
low complexity region
|
723 |
739 |
N/A |
INTRINSIC |
|
| Meta Mutation Damage Score |
0.6467 |
| Coding Region Coverage |
- 1x: 99.3%
- 3x: 98.7%
- 10x: 97.4%
- 20x: 95.5%
|
| Validation Efficiency |
|
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene encodes a member of the cancer testis antigen gene family. The encoded protein functions as a scaffold protein that structurally organizes mitogen-activated protein kinases and mediates c-Jun-terminal kinase signaling. This protein also binds to kinesin-1 and may be involved in microtubule-based membrane transport. This protein may play a role in tumor growth and development. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Oct 2011]
PHENOTYPE: Male mice homozygous for a null mutation display reduced fertility with oligoasthenozoospermia. [provided by MGI curators]
|
| Allele List at MGI |
All alleles(5) : Targeted, knock-out(1) Gene trapped(4) |
| Other mutations in this stock |
Total: 53 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| A1cf |
C |
T |
19: 31,944,982 (GRCm38) |
Q448* |
probably null |
Het |
| Abca5 |
A |
G |
11: 110,301,536 (GRCm38) |
Y717H |
probably benign |
Het |
| Abcg2 |
T |
A |
6: 58,672,056 (GRCm38) |
D295E |
probably damaging |
Het |
| Accsl |
C |
T |
2: 93,869,025 (GRCm38) |
E7K |
probably benign |
Het |
| Acvr2b |
A |
G |
9: 119,428,309 (GRCm38) |
Y152C |
probably damaging |
Het |
| Akap13 |
A |
G |
7: 75,704,372 (GRCm38) |
E1747G |
probably damaging |
Het |
| Arpp19 |
C |
T |
9: 75,037,933 (GRCm38) |
|
probably benign |
Het |
| Atp10d |
A |
G |
5: 72,288,219 (GRCm38) |
Y74C |
probably damaging |
Het |
| Atp6v0b |
T |
C |
4: 117,886,385 (GRCm38) |
|
probably benign |
Het |
| Bms1 |
C |
A |
6: 118,388,825 (GRCm38) |
M1133I |
probably benign |
Het |
| Bysl |
A |
C |
17: 47,602,723 (GRCm38) |
D259E |
probably benign |
Het |
| Capn1 |
A |
T |
19: 6,014,442 (GRCm38) |
V9E |
probably benign |
Het |
| Cdkl2 |
T |
C |
5: 92,033,742 (GRCm38) |
I127V |
probably benign |
Het |
| Cyp2c38 |
G |
A |
19: 39,438,306 (GRCm38) |
Q184* |
probably null |
Het |
| Cypt12 |
C |
T |
3: 17,948,585 (GRCm38) |
R41C |
probably benign |
Het |
| Dnaaf11 |
A |
T |
15: 66,500,816 (GRCm38) |
|
probably null |
Het |
| Fat2 |
T |
C |
11: 55,282,481 (GRCm38) |
I2469V |
probably damaging |
Het |
| Fbxo38 |
A |
G |
18: 62,511,018 (GRCm38) |
V923A |
possibly damaging |
Het |
| Gm13889 |
A |
G |
2: 93,956,686 (GRCm38) |
C148R |
probably damaging |
Het |
| Gpd1 |
A |
T |
15: 99,722,058 (GRCm38) |
T223S |
probably benign |
Het |
| Hcrtr1 |
C |
A |
4: 130,130,945 (GRCm38) |
G383C |
possibly damaging |
Het |
| Hivep1 |
C |
T |
13: 42,163,456 (GRCm38) |
P2047S |
possibly damaging |
Het |
| Islr2 |
T |
C |
9: 58,201,301 (GRCm38) |
T35A |
probably benign |
Het |
| Lgr6 |
T |
C |
1: 134,987,078 (GRCm38) |
D644G |
probably benign |
Het |
| Mdn1 |
C |
T |
4: 32,695,480 (GRCm38) |
T1173I |
probably damaging |
Het |
| Mon1a |
T |
C |
9: 107,901,240 (GRCm38) |
V221A |
probably damaging |
Het |
| Mrgprb4 |
A |
G |
7: 48,198,470 (GRCm38) |
C237R |
probably benign |
Het |
| Myo1b |
A |
G |
1: 51,797,528 (GRCm38) |
M264T |
probably damaging |
Het |
| Naxd |
A |
G |
8: 11,502,676 (GRCm38) |
N32S |
probably benign |
Het |
| Nlrp12 |
A |
T |
7: 3,225,294 (GRCm38) |
L1010Q |
probably damaging |
Het |
| Nos1ap |
T |
A |
1: 170,349,399 (GRCm38) |
K145M |
probably damaging |
Het |
| Nuggc |
A |
T |
14: 65,648,188 (GRCm38) |
K755* |
probably null |
Het |
| Or2av9 |
T |
C |
11: 58,490,051 (GRCm38) |
K235E |
probably damaging |
Het |
| Or9i2 |
C |
T |
19: 13,838,337 (GRCm38) |
V279M |
possibly damaging |
Het |
| Pik3ca |
G |
A |
3: 32,461,560 (GRCm38) |
R794Q |
probably damaging |
Het |
| Pnp2 |
A |
G |
14: 50,956,192 (GRCm38) |
|
probably null |
Het |
| Ric3 |
G |
A |
7: 109,038,820 (GRCm38) |
T242I |
probably damaging |
Het |
| Rnf213 |
G |
A |
11: 119,436,629 (GRCm38) |
R1814K |
probably benign |
Het |
| Rnf213 |
A |
C |
11: 119,436,905 (GRCm38) |
Q1906P |
probably damaging |
Het |
| Rufy2 |
T |
A |
10: 62,997,954 (GRCm38) |
I265N |
probably damaging |
Het |
| Scap |
G |
T |
9: 110,380,594 (GRCm38) |
G744C |
probably damaging |
Het |
| Serpinb3c |
T |
C |
1: 107,275,014 (GRCm38) |
Q88R |
possibly damaging |
Het |
| Sf3b1 |
T |
C |
1: 54,997,193 (GRCm38) |
D907G |
probably damaging |
Het |
| Skint8 |
C |
A |
4: 111,950,193 (GRCm38) |
L359M |
probably damaging |
Het |
| Slc4a3 |
C |
T |
1: 75,554,216 (GRCm38) |
L749F |
possibly damaging |
Het |
| Smtn |
T |
G |
11: 3,517,829 (GRCm38) |
|
probably null |
Het |
| Sptbn5 |
G |
A |
2: 120,057,404 (GRCm38) |
|
probably benign |
Het |
| Stam |
G |
T |
2: 14,117,427 (GRCm38) |
M112I |
probably damaging |
Het |
| Tex35 |
C |
T |
1: 157,100,224 (GRCm38) |
W125* |
probably null |
Het |
| Tmem215 |
A |
G |
4: 40,474,394 (GRCm38) |
E157G |
probably damaging |
Het |
| Traf6 |
G |
A |
2: 101,696,909 (GRCm38) |
V335M |
probably benign |
Het |
| Ubr5 |
T |
A |
15: 37,983,996 (GRCm38) |
K2302N |
probably damaging |
Het |
| Vmn2r78 |
A |
G |
7: 86,954,429 (GRCm38) |
H605R |
probably damaging |
Het |
|
| Other mutations in Spag9 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00422:Spag9
|
APN |
11 |
94,097,866 (GRCm38) |
missense |
probably benign |
0.02 |
|
IGL01776:Spag9
|
APN |
11 |
94,116,727 (GRCm38) |
splice site |
probably benign |
|
|
IGL02095:Spag9
|
APN |
11 |
94,108,582 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL02307:Spag9
|
APN |
11 |
94,102,160 (GRCm38) |
critical splice donor site |
probably null |
|
|
IGL02417:Spag9
|
APN |
11 |
94,116,741 (GRCm38) |
missense |
probably benign |
0.27 |
|
IGL02480:Spag9
|
APN |
11 |
94,108,587 (GRCm38) |
nonsense |
probably null |
|
|
IGL02864:Spag9
|
APN |
11 |
94,106,661 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL02976:Spag9
|
APN |
11 |
94,083,953 (GRCm38) |
missense |
probably benign |
0.30 |
|
IGL02979:Spag9
|
APN |
11 |
94,097,364 (GRCm38) |
missense |
probably benign |
|
|
IGL03349:Spag9
|
APN |
11 |
94,093,509 (GRCm38) |
missense |
possibly damaging |
0.51 |
|
dazzle
|
UTSW |
11 |
94,093,624 (GRCm38) |
nonsense |
probably null |
|
|
R0128:Spag9
|
UTSW |
11 |
94,093,539 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R0418:Spag9
|
UTSW |
11 |
94,091,753 (GRCm38) |
splice site |
probably benign |
|
|
R1463:Spag9
|
UTSW |
11 |
94,116,837 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R1593:Spag9
|
UTSW |
11 |
94,097,233 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R1605:Spag9
|
UTSW |
11 |
94,048,539 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R1649:Spag9
|
UTSW |
11 |
94,108,452 (GRCm38) |
splice site |
probably null |
|
|
R1697:Spag9
|
UTSW |
11 |
93,996,565 (GRCm38) |
missense |
probably benign |
0.00 |
|
R1952:Spag9
|
UTSW |
11 |
94,097,358 (GRCm38) |
missense |
possibly damaging |
0.77 |
|
R2011:Spag9
|
UTSW |
11 |
94,092,375 (GRCm38) |
nonsense |
probably null |
|
|
R2012:Spag9
|
UTSW |
11 |
94,092,375 (GRCm38) |
nonsense |
probably null |
|
|
R2351:Spag9
|
UTSW |
11 |
94,092,900 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R2367:Spag9
|
UTSW |
11 |
94,116,757 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R3027:Spag9
|
UTSW |
11 |
94,086,377 (GRCm38) |
missense |
probably null |
1.00 |
|
R3766:Spag9
|
UTSW |
11 |
94,060,283 (GRCm38) |
intron |
probably benign |
|
|
R3777:Spag9
|
UTSW |
11 |
94,099,026 (GRCm38) |
critical splice acceptor site |
probably null |
|
|
R3937:Spag9
|
UTSW |
11 |
94,044,479 (GRCm38) |
missense |
possibly damaging |
0.92 |
|
R3937:Spag9
|
UTSW |
11 |
94,044,417 (GRCm38) |
missense |
possibly damaging |
0.94 |
|
R4417:Spag9
|
UTSW |
11 |
94,060,346 (GRCm38) |
intron |
probably benign |
|
|
R4445:Spag9
|
UTSW |
11 |
94,097,253 (GRCm38) |
missense |
possibly damaging |
0.95 |
|
R4711:Spag9
|
UTSW |
11 |
94,114,351 (GRCm38) |
critical splice donor site |
probably null |
|
|
R4799:Spag9
|
UTSW |
11 |
94,048,517 (GRCm38) |
missense |
probably damaging |
0.96 |
|
R4799:Spag9
|
UTSW |
11 |
94,048,516 (GRCm38) |
missense |
possibly damaging |
0.87 |
|
R4816:Spag9
|
UTSW |
11 |
94,048,599 (GRCm38) |
intron |
probably benign |
|
|
R4843:Spag9
|
UTSW |
11 |
94,097,818 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R5020:Spag9
|
UTSW |
11 |
94,097,786 (GRCm38) |
missense |
probably benign |
0.08 |
|
R5119:Spag9
|
UTSW |
11 |
94,122,722 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R5298:Spag9
|
UTSW |
11 |
94,100,135 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R5304:Spag9
|
UTSW |
11 |
94,069,012 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R5305:Spag9
|
UTSW |
11 |
94,069,012 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R5395:Spag9
|
UTSW |
11 |
94,091,751 (GRCm38) |
splice site |
probably null |
|
|
R5638:Spag9
|
UTSW |
11 |
94,069,012 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R5654:Spag9
|
UTSW |
11 |
94,090,712 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R5779:Spag9
|
UTSW |
11 |
94,114,253 (GRCm38) |
missense |
probably benign |
0.20 |
|
R5814:Spag9
|
UTSW |
11 |
94,082,828 (GRCm38) |
missense |
possibly damaging |
0.94 |
|
R5912:Spag9
|
UTSW |
11 |
94,044,425 (GRCm38) |
missense |
probably damaging |
0.98 |
|
R6038:Spag9
|
UTSW |
11 |
94,112,092 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R6038:Spag9
|
UTSW |
11 |
94,112,092 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R6269:Spag9
|
UTSW |
11 |
94,044,507 (GRCm38) |
missense |
probably benign |
0.05 |
|
R6294:Spag9
|
UTSW |
11 |
94,093,485 (GRCm38) |
critical splice acceptor site |
probably null |
|
|
R6389:Spag9
|
UTSW |
11 |
94,086,311 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R6420:Spag9
|
UTSW |
11 |
94,086,302 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R6460:Spag9
|
UTSW |
11 |
94,068,975 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R6482:Spag9
|
UTSW |
11 |
94,093,502 (GRCm38) |
missense |
possibly damaging |
0.94 |
|
R6860:Spag9
|
UTSW |
11 |
94,081,370 (GRCm38) |
missense |
probably benign |
0.25 |
|
R7086:Spag9
|
UTSW |
11 |
94,097,864 (GRCm38) |
missense |
probably benign |
|
|
R7179:Spag9
|
UTSW |
11 |
94,089,432 (GRCm38) |
splice site |
probably null |
|
|
R7225:Spag9
|
UTSW |
11 |
94,097,358 (GRCm38) |
missense |
probably damaging |
0.98 |
|
R7351:Spag9
|
UTSW |
11 |
94,092,976 (GRCm38) |
missense |
probably benign |
0.00 |
|
R7366:Spag9
|
UTSW |
11 |
94,108,521 (GRCm38) |
missense |
possibly damaging |
0.56 |
|
R7378:Spag9
|
UTSW |
11 |
94,114,351 (GRCm38) |
critical splice donor site |
probably null |
|
|
R7401:Spag9
|
UTSW |
11 |
94,097,689 (GRCm38) |
missense |
probably benign |
|
|
R7506:Spag9
|
UTSW |
11 |
94,108,464 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R7507:Spag9
|
UTSW |
11 |
94,068,080 (GRCm38) |
missense |
probably benign |
0.00 |
|
R7513:Spag9
|
UTSW |
11 |
94,112,083 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R7655:Spag9
|
UTSW |
11 |
93,996,563 (GRCm38) |
missense |
possibly damaging |
0.56 |
|
R7656:Spag9
|
UTSW |
11 |
93,996,563 (GRCm38) |
missense |
possibly damaging |
0.56 |
|
R7664:Spag9
|
UTSW |
11 |
94,102,160 (GRCm38) |
critical splice donor site |
probably null |
|
|
R7665:Spag9
|
UTSW |
11 |
94,013,654 (GRCm38) |
missense |
probably damaging |
0.98 |
|
R7862:Spag9
|
UTSW |
11 |
94,112,066 (GRCm38) |
missense |
possibly damaging |
0.69 |
|
R8074:Spag9
|
UTSW |
11 |
94,112,051 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R8085:Spag9
|
UTSW |
11 |
94,099,044 (GRCm38) |
missense |
probably benign |
|
|
R8469:Spag9
|
UTSW |
11 |
94,091,801 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R8547:Spag9
|
UTSW |
11 |
94,122,821 (GRCm38) |
missense |
possibly damaging |
0.84 |
|
R8709:Spag9
|
UTSW |
11 |
94,068,090 (GRCm38) |
missense |
probably benign |
0.02 |
|
R8732:Spag9
|
UTSW |
11 |
94,071,688 (GRCm38) |
critical splice donor site |
probably null |
|
|
R8899:Spag9
|
UTSW |
11 |
94,092,869 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R8983:Spag9
|
UTSW |
11 |
94,067,989 (GRCm38) |
missense |
probably benign |
|
|
R9043:Spag9
|
UTSW |
11 |
94,060,259 (GRCm38) |
missense |
|
|
|
R9050:Spag9
|
UTSW |
11 |
94,044,468 (GRCm38) |
missense |
probably damaging |
0.97 |
|
R9502:Spag9
|
UTSW |
11 |
94,068,966 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R9575:Spag9
|
UTSW |
11 |
94,071,583 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R9667:Spag9
|
UTSW |
11 |
93,996,293 (GRCm38) |
missense |
possibly damaging |
0.83 |
|
R9683:Spag9
|
UTSW |
11 |
94,097,742 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R9774:Spag9
|
UTSW |
11 |
94,114,236 (GRCm38) |
missense |
probably damaging |
0.96 |
|
| Predicted Primers |
PCR Primer
(F):5'- ACACAGCCACGAGAGTTTC -3'
(R):5'- CTGCCAGAAGAATGTCCTCC -3'
Sequencing Primer
(F):5'- CAGCCACGAGAGTTTCTAAAAATG -3'
(R):5'- GCACAACATGAACTGATCT -3'
|
| Posted On |
2016-11-08 |
Incidental Mutation