Incidental Mutation 'R5643:Lmo7'
| ID |
440891 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Lmo7
|
| Ensembl Gene |
ENSMUSG00000033060 |
| Gene Name |
LIM domain only 7 |
| Synonyms |
FBXO20, LOC380928 |
| MMRRC Submission |
043291-MU
|
| Accession Numbers |
|
| Essential gene? |
Probably non essential
(E-score: 0.133)
|
| Stock # |
R5643 (G1)
|
| Quality Score |
225 |
|
Status
|
Validated
|
| Chromosome |
14 |
| Chromosomal Location |
101967393-102172146 bp(+) (GRCm39) |
| Type of Mutation |
utr 3 prime |
| DNA Base Change (assembly) |
A to G
at 102166772 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000125465
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000100337]
[ENSMUST00000159258]
[ENSMUST00000159314]
[ENSMUST00000159597]
|
| AlphaFold |
E9PYF4 |
| Predicted Effect |
unknown
Transcript: ENSMUST00000100337
AA Change: N1584D
|
| SMART Domains |
Protein: ENSMUSP00000097910
Gene: ENSMUSG00000033060
AA Change: N1584D
| Domain | Start | End | E-Value | Type |
|---|
|
CH
|
14 |
124 |
2.57e-13 |
SMART |
|
low complexity region
|
200 |
211 |
N/A |
INTRINSIC |
|
Pfam:DUF4757
|
242 |
348 |
2.2e-14 |
PFAM |
|
low complexity region
|
448 |
462 |
N/A |
INTRINSIC |
|
Pfam:DUF4757
|
568 |
735 |
1.8e-46 |
PFAM |
|
low complexity region
|
861 |
879 |
N/A |
INTRINSIC |
|
low complexity region
|
979 |
991 |
N/A |
INTRINSIC |
|
low complexity region
|
1003 |
1015 |
N/A |
INTRINSIC |
|
PDZ
|
1047 |
1119 |
1.05e-8 |
SMART |
|
coiled coil region
|
1222 |
1275 |
N/A |
INTRINSIC |
|
coiled coil region
|
1319 |
1411 |
N/A |
INTRINSIC |
|
low complexity region
|
1585 |
1596 |
N/A |
INTRINSIC |
|
low complexity region
|
1599 |
1617 |
N/A |
INTRINSIC |
|
LIM
|
1629 |
1687 |
6.54e-10 |
SMART |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000159154
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000159258
|
| SMART Domains |
Protein: ENSMUSP00000125465
Gene: ENSMUSG00000033060
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
215 |
229 |
N/A |
INTRINSIC |
|
| Predicted Effect |
unknown
Transcript: ENSMUST00000159314
AA Change: N1351D
|
| SMART Domains |
Protein: ENSMUSP00000124349
Gene: ENSMUSG00000033060
AA Change: N1351D
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
215 |
229 |
N/A |
INTRINSIC |
|
coiled coil region
|
435 |
492 |
N/A |
INTRINSIC |
|
low complexity region
|
628 |
646 |
N/A |
INTRINSIC |
|
low complexity region
|
746 |
758 |
N/A |
INTRINSIC |
|
low complexity region
|
770 |
782 |
N/A |
INTRINSIC |
|
PDZ
|
814 |
886 |
1.05e-8 |
SMART |
|
coiled coil region
|
989 |
1042 |
N/A |
INTRINSIC |
|
coiled coil region
|
1086 |
1178 |
N/A |
INTRINSIC |
|
low complexity region
|
1352 |
1363 |
N/A |
INTRINSIC |
|
low complexity region
|
1366 |
1384 |
N/A |
INTRINSIC |
|
| Predicted Effect |
unknown
Transcript: ENSMUST00000159597
AA Change: N1489D
|
| SMART Domains |
Protein: ENSMUSP00000123706
Gene: ENSMUSG00000033060
AA Change: N1489D
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
78 |
89 |
N/A |
INTRINSIC |
|
internal_repeat_1
|
111 |
141 |
6.96e-5 |
PROSPERO |
|
internal_repeat_1
|
218 |
248 |
6.96e-5 |
PROSPERO |
|
low complexity region
|
326 |
340 |
N/A |
INTRINSIC |
|
coiled coil region
|
546 |
603 |
N/A |
INTRINSIC |
|
low complexity region
|
739 |
757 |
N/A |
INTRINSIC |
|
low complexity region
|
857 |
869 |
N/A |
INTRINSIC |
|
low complexity region
|
881 |
893 |
N/A |
INTRINSIC |
|
PDZ
|
925 |
997 |
1.05e-8 |
SMART |
|
coiled coil region
|
1127 |
1180 |
N/A |
INTRINSIC |
|
coiled coil region
|
1224 |
1316 |
N/A |
INTRINSIC |
|
low complexity region
|
1490 |
1501 |
N/A |
INTRINSIC |
|
low complexity region
|
1504 |
1522 |
N/A |
INTRINSIC |
|
LIM
|
1534 |
1592 |
6.54e-10 |
SMART |
|
| Predicted Effect |
unknown
Transcript: ENSMUST00000159806
AA Change: N1073D
|
| SMART Domains |
Protein: ENSMUSP00000124300
Gene: ENSMUSG00000033060
AA Change: N1073D
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
34 |
45 |
N/A |
INTRINSIC |
|
Pfam:DUF4757
|
76 |
225 |
4.5e-53 |
PFAM |
|
low complexity region
|
351 |
369 |
N/A |
INTRINSIC |
|
low complexity region
|
469 |
481 |
N/A |
INTRINSIC |
|
low complexity region
|
493 |
505 |
N/A |
INTRINSIC |
|
PDZ
|
537 |
609 |
1.05e-8 |
SMART |
|
internal_repeat_1
|
620 |
691 |
9.31e-5 |
PROSPERO |
|
coiled coil region
|
711 |
764 |
N/A |
INTRINSIC |
|
coiled coil region
|
808 |
900 |
N/A |
INTRINSIC |
|
internal_repeat_1
|
921 |
976 |
9.31e-5 |
PROSPERO |
|
low complexity region
|
1075 |
1086 |
N/A |
INTRINSIC |
|
low complexity region
|
1089 |
1107 |
N/A |
INTRINSIC |
|
LIM
|
1119 |
1177 |
6.54e-10 |
SMART |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000159850
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000160038
|
| Meta Mutation Damage Score |
0.0624 |
| Coding Region Coverage |
- 1x: 99.3%
- 3x: 98.6%
- 10x: 97.2%
- 20x: 95.2%
|
| Validation Efficiency |
94% (110/117) |
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene encodes a protein containing a calponin homology (CH) domain, a PDZ domain, and a LIM domain, and may be involved in protein-protein interactions. Several alternatively spliced transcript variants encoding different isoforms have been found for this gene, however, the full-length nature of some variants is not known. [provided by RefSeq, Jan 2009]
PHENOTYPE: Targeted mutations in this gene result in postnatal lethality, growth defects, skeletal muscle abnormalities and retinal defects reflective of retinal degeneration. [provided by MGI curators]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 102 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Ahnak |
A |
G |
19: 8,988,021 (GRCm39) |
K3102E |
possibly damaging |
Het |
| Akap13 |
T |
C |
7: 75,351,902 (GRCm39) |
|
probably null |
Het |
| Akp3 |
A |
T |
1: 87,055,485 (GRCm39) |
T511S |
unknown |
Het |
| Alkal2 |
T |
A |
12: 30,934,889 (GRCm39) |
L36Q |
probably damaging |
Het |
| Arhgef17 |
A |
T |
7: 100,529,218 (GRCm39) |
V523E |
probably damaging |
Het |
| Asah1 |
G |
T |
8: 41,813,332 (GRCm39) |
T27K |
possibly damaging |
Het |
| Bag2 |
A |
G |
1: 33,786,034 (GRCm39) |
V96A |
probably damaging |
Het |
| Bicd1 |
C |
T |
6: 149,421,901 (GRCm39) |
A874V |
probably damaging |
Het |
| C4b |
T |
C |
17: 34,961,391 (GRCm39) |
I189M |
probably benign |
Het |
| Calcr |
A |
G |
6: 3,708,538 (GRCm39) |
I216T |
probably damaging |
Het |
| Cdk5rap2 |
T |
A |
4: 70,184,970 (GRCm39) |
D1160V |
probably damaging |
Het |
| Cep128 |
A |
T |
12: 91,315,625 (GRCm39) |
I87K |
probably damaging |
Het |
| Cep170b |
C |
G |
12: 112,707,275 (GRCm39) |
H1256Q |
probably benign |
Het |
| Chd2 |
A |
T |
7: 73,134,232 (GRCm39) |
V705E |
probably damaging |
Het |
| Clec12b |
T |
A |
6: 129,356,923 (GRCm39) |
I172L |
probably benign |
Het |
| Cobl |
A |
T |
11: 12,256,948 (GRCm39) |
|
probably benign |
Het |
| Col5a2 |
T |
A |
1: 45,429,202 (GRCm39) |
D972V |
probably damaging |
Het |
| Csrp1 |
A |
T |
1: 135,678,797 (GRCm39) |
N174I |
probably damaging |
Het |
| Dnah7a |
T |
A |
1: 53,444,866 (GRCm39) |
H3946L |
probably benign |
Het |
| Dnajc21 |
A |
T |
15: 10,462,001 (GRCm39) |
D133E |
probably benign |
Het |
| Dvl3 |
T |
A |
16: 20,345,026 (GRCm39) |
I353N |
probably damaging |
Het |
| Elavl3 |
A |
T |
9: 21,930,029 (GRCm39) |
S292T |
probably benign |
Het |
| Ephb2 |
T |
C |
4: 136,498,923 (GRCm39) |
N52S |
probably damaging |
Het |
| Gaa |
T |
A |
11: 119,171,361 (GRCm39) |
M671K |
possibly damaging |
Het |
| Gabrg3 |
T |
C |
7: 56,423,032 (GRCm39) |
D222G |
possibly damaging |
Het |
| Gk5 |
C |
T |
9: 96,022,709 (GRCm39) |
Q182* |
probably null |
Het |
| Gm14403 |
A |
T |
2: 177,199,054 (GRCm39) |
H50L |
possibly damaging |
Het |
| Gzma |
T |
C |
13: 113,234,794 (GRCm39) |
T66A |
probably damaging |
Het |
| Hint2 |
T |
C |
4: 43,656,445 (GRCm39) |
|
probably benign |
Het |
| Hnmt |
A |
T |
2: 23,904,251 (GRCm39) |
W137R |
probably damaging |
Het |
| Hoga1 |
T |
C |
19: 42,048,402 (GRCm39) |
V90A |
probably benign |
Het |
| Idua |
A |
T |
5: 108,828,090 (GRCm39) |
|
probably benign |
Het |
| Kif1a |
A |
C |
1: 92,983,489 (GRCm39) |
S669R |
probably damaging |
Het |
| Klhdc7b |
A |
T |
15: 89,271,862 (GRCm39) |
M915L |
possibly damaging |
Het |
| Klhl41 |
A |
G |
2: 69,500,815 (GRCm39) |
Y92C |
probably damaging |
Het |
| Klrc2 |
A |
T |
6: 129,633,420 (GRCm39) |
C186S |
probably damaging |
Het |
| Lrriq1 |
T |
C |
10: 103,051,301 (GRCm39) |
M484V |
probably benign |
Het |
| Lzts1 |
A |
G |
8: 69,591,729 (GRCm39) |
S140P |
possibly damaging |
Het |
| Mgat5b |
T |
A |
11: 116,864,226 (GRCm39) |
V464E |
probably damaging |
Het |
| Mms19 |
A |
T |
19: 41,944,305 (GRCm39) |
D298E |
possibly damaging |
Het |
| Muc5ac |
T |
C |
7: 141,347,452 (GRCm39) |
|
probably null |
Het |
| Mycbp2 |
T |
A |
14: 103,524,770 (GRCm39) |
K597I |
probably damaging |
Het |
| Myo18a |
C |
A |
11: 77,745,513 (GRCm39) |
D1619E |
probably benign |
Het |
| Nfx1 |
T |
C |
4: 40,984,973 (GRCm39) |
W366R |
probably null |
Het |
| Nipbl |
C |
T |
15: 8,388,391 (GRCm39) |
V410I |
probably benign |
Het |
| Or14j10 |
T |
A |
17: 37,935,323 (GRCm39) |
I68F |
probably benign |
Het |
| Or4c101 |
T |
A |
2: 88,389,849 (GRCm39) |
M1K |
probably null |
Het |
| Or4f60 |
A |
T |
2: 111,902,013 (GRCm39) |
M305K |
probably benign |
Het |
| Or52h1 |
T |
C |
7: 103,829,091 (GRCm39) |
I175V |
probably benign |
Het |
| Or5b95 |
A |
T |
19: 12,658,336 (GRCm39) |
Y288F |
probably damaging |
Het |
| Or7g32 |
A |
T |
9: 19,388,853 (GRCm39) |
M231K |
probably benign |
Het |
| Or8u10 |
T |
C |
2: 85,915,503 (GRCm39) |
N206S |
probably damaging |
Het |
| Otog |
A |
T |
7: 45,936,871 (GRCm39) |
T1527S |
probably damaging |
Het |
| P2ry12 |
A |
T |
3: 59,125,516 (GRCm39) |
M53K |
possibly damaging |
Het |
| Pask |
A |
G |
1: 93,265,065 (GRCm39) |
|
probably null |
Het |
| Pcca |
G |
A |
14: 123,124,481 (GRCm39) |
C684Y |
probably damaging |
Het |
| Pcdhb10 |
A |
G |
18: 37,546,219 (GRCm39) |
T432A |
possibly damaging |
Het |
| Peak1 |
T |
C |
9: 56,166,039 (GRCm39) |
N630D |
probably damaging |
Het |
| Plbd2 |
A |
T |
5: 120,631,231 (GRCm39) |
|
probably null |
Het |
| Plekhg5 |
T |
C |
4: 152,188,797 (GRCm39) |
V200A |
probably benign |
Het |
| Pola2 |
A |
G |
19: 6,011,198 (GRCm39) |
V42A |
probably benign |
Het |
| Ppfibp2 |
T |
A |
7: 107,337,097 (GRCm39) |
W572R |
probably damaging |
Het |
| Ppp6r1 |
C |
T |
7: 4,636,771 (GRCm39) |
E679K |
probably benign |
Het |
| Pramel11 |
A |
T |
4: 143,622,337 (GRCm39) |
H339Q |
probably damaging |
Het |
| Prdx3 |
G |
A |
19: 60,859,963 (GRCm39) |
A70V |
probably damaging |
Het |
| Prkd2 |
T |
C |
7: 16,577,717 (GRCm39) |
F57L |
probably benign |
Het |
| Prodh2 |
A |
G |
7: 30,206,171 (GRCm39) |
T324A |
possibly damaging |
Het |
| Ptdss1 |
T |
C |
13: 67,120,604 (GRCm39) |
F267L |
probably damaging |
Het |
| Rai14 |
T |
A |
15: 10,593,137 (GRCm39) |
H169L |
probably benign |
Het |
| Rere |
A |
G |
4: 150,701,700 (GRCm39) |
H1360R |
probably damaging |
Het |
| Rfc3 |
C |
T |
5: 151,573,444 (GRCm39) |
V40I |
probably benign |
Het |
| Rims1 |
T |
A |
1: 22,577,590 (GRCm39) |
T219S |
probably damaging |
Het |
| Rnf169 |
T |
C |
7: 99,576,338 (GRCm39) |
R289G |
possibly damaging |
Het |
| Senp7 |
T |
C |
16: 56,004,512 (GRCm39) |
|
silent |
Het |
| Sfmbt2 |
A |
T |
2: 10,573,184 (GRCm39) |
I571F |
probably damaging |
Het |
| Slc11a2 |
C |
A |
15: 100,301,068 (GRCm39) |
K328N |
probably benign |
Het |
| Slc25a10 |
A |
G |
11: 120,387,202 (GRCm39) |
|
probably benign |
Het |
| Slc38a8 |
T |
C |
8: 120,207,488 (GRCm39) |
*433W |
probably null |
Het |
| Slco1a5 |
A |
C |
6: 142,183,320 (GRCm39) |
|
probably null |
Het |
| Smc6 |
T |
A |
12: 11,339,995 (GRCm39) |
N434K |
probably benign |
Het |
| Syndig1 |
A |
T |
2: 149,741,428 (GRCm39) |
I5F |
possibly damaging |
Het |
| Syt5 |
T |
C |
7: 4,546,018 (GRCm39) |
Q124R |
probably benign |
Het |
| Taok3 |
A |
C |
5: 117,344,785 (GRCm39) |
M171L |
probably benign |
Het |
| Tbrg1 |
T |
C |
9: 37,560,709 (GRCm39) |
D389G |
probably benign |
Het |
| Tcaf2 |
G |
A |
6: 42,619,707 (GRCm39) |
R107C |
possibly damaging |
Het |
| Tex14 |
C |
A |
11: 87,426,452 (GRCm39) |
H1159Q |
probably damaging |
Het |
| Tmprss11d |
T |
A |
5: 86,474,388 (GRCm39) |
M190L |
probably benign |
Het |
| Ttn |
T |
A |
2: 76,768,867 (GRCm39) |
T2856S |
probably damaging |
Het |
| Ubr4 |
T |
A |
4: 139,171,998 (GRCm39) |
M2997K |
probably damaging |
Het |
| Unc5c |
C |
T |
3: 141,383,886 (GRCm39) |
A88V |
probably damaging |
Het |
| Use1 |
T |
C |
8: 71,820,398 (GRCm39) |
|
probably benign |
Het |
| Vmn1r43 |
T |
C |
6: 89,847,354 (GRCm39) |
N44S |
probably damaging |
Het |
| Vmn1r89 |
T |
A |
7: 12,954,146 (GRCm39) |
V294D |
possibly damaging |
Het |
| Vmn2r11 |
A |
T |
5: 109,194,869 (GRCm39) |
V819E |
probably damaging |
Het |
| Vmn2r120 |
T |
A |
17: 57,831,977 (GRCm39) |
M271L |
probably benign |
Het |
| Vmn2r52 |
T |
C |
7: 9,905,059 (GRCm39) |
Y260C |
probably damaging |
Het |
| Vmn2r67 |
T |
A |
7: 84,799,151 (GRCm39) |
R519* |
probably null |
Het |
| Vmn2r69 |
T |
A |
7: 85,056,404 (GRCm39) |
D578V |
probably damaging |
Het |
| Vmn2r85 |
T |
C |
10: 130,262,343 (GRCm39) |
Y132C |
probably damaging |
Het |
| Wdr74 |
T |
A |
19: 8,715,240 (GRCm39) |
V133E |
probably damaging |
Het |
| Zfp318 |
T |
A |
17: 46,720,170 (GRCm39) |
|
probably benign |
Het |
| Zfp810 |
A |
T |
9: 22,194,467 (GRCm39) |
S74T |
probably benign |
Het |
|
| Other mutations in Lmo7 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00569:Lmo7
|
APN |
14 |
102,124,487 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL00733:Lmo7
|
APN |
14 |
102,153,138 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL00778:Lmo7
|
APN |
14 |
102,148,321 (GRCm39) |
splice site |
probably benign |
|
|
IGL01014:Lmo7
|
APN |
14 |
102,157,993 (GRCm39) |
splice site |
probably benign |
|
|
IGL01401:Lmo7
|
APN |
14 |
102,031,713 (GRCm39) |
nonsense |
probably null |
|
|
IGL01550:Lmo7
|
APN |
14 |
102,163,576 (GRCm39) |
utr 3 prime |
probably benign |
|
|
IGL01570:Lmo7
|
APN |
14 |
102,139,807 (GRCm39) |
critical splice donor site |
probably null |
|
|
IGL01602:Lmo7
|
APN |
14 |
102,148,192 (GRCm39) |
splice site |
probably benign |
|
|
IGL01605:Lmo7
|
APN |
14 |
102,148,192 (GRCm39) |
splice site |
probably benign |
|
|
IGL02012:Lmo7
|
APN |
14 |
102,126,152 (GRCm39) |
intron |
probably benign |
|
|
IGL02145:Lmo7
|
APN |
14 |
102,139,659 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL02236:Lmo7
|
APN |
14 |
102,163,524 (GRCm39) |
splice site |
probably benign |
|
|
IGL02318:Lmo7
|
APN |
14 |
102,137,502 (GRCm39) |
splice site |
probably benign |
|
|
IGL02345:Lmo7
|
APN |
14 |
102,124,909 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02498:Lmo7
|
APN |
14 |
102,044,918 (GRCm39) |
missense |
probably benign |
0.01 |
|
IGL02583:Lmo7
|
APN |
14 |
102,171,360 (GRCm39) |
utr 3 prime |
probably benign |
|
|
IGL02670:Lmo7
|
APN |
14 |
102,118,416 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02694:Lmo7
|
APN |
14 |
102,124,606 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03026:Lmo7
|
APN |
14 |
102,166,769 (GRCm39) |
utr 3 prime |
probably benign |
|
|
IGL03062:Lmo7
|
APN |
14 |
102,149,515 (GRCm39) |
missense |
possibly damaging |
0.66 |
|
IGL03068:Lmo7
|
APN |
14 |
102,112,928 (GRCm39) |
unclassified |
probably benign |
|
|
IGL03178:Lmo7
|
APN |
14 |
102,166,696 (GRCm39) |
nonsense |
probably null |
|
|
IGL03279:Lmo7
|
APN |
14 |
102,137,944 (GRCm39) |
missense |
probably benign |
0.30 |
|
PIT4458001:Lmo7
|
UTSW |
14 |
102,124,923 (GRCm39) |
nonsense |
probably null |
|
|
R0029:Lmo7
|
UTSW |
14 |
102,171,357 (GRCm39) |
utr 3 prime |
probably benign |
|
|
R0112:Lmo7
|
UTSW |
14 |
102,124,629 (GRCm39) |
nonsense |
probably null |
|
|
R0345:Lmo7
|
UTSW |
14 |
102,114,313 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0372:Lmo7
|
UTSW |
14 |
102,155,489 (GRCm39) |
splice site |
probably benign |
|
|
R0393:Lmo7
|
UTSW |
14 |
102,137,892 (GRCm39) |
missense |
probably benign |
|
|
R0514:Lmo7
|
UTSW |
14 |
102,133,995 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0514:Lmo7
|
UTSW |
14 |
102,124,609 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0526:Lmo7
|
UTSW |
14 |
102,137,996 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0615:Lmo7
|
UTSW |
14 |
102,114,295 (GRCm39) |
nonsense |
probably null |
|
|
R0900:Lmo7
|
UTSW |
14 |
102,124,624 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0961:Lmo7
|
UTSW |
14 |
102,031,705 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0964:Lmo7
|
UTSW |
14 |
102,158,003 (GRCm39) |
splice site |
probably benign |
|
|
R1078:Lmo7
|
UTSW |
14 |
102,157,910 (GRCm39) |
splice site |
probably benign |
|
|
R1252:Lmo7
|
UTSW |
14 |
102,138,019 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1527:Lmo7
|
UTSW |
14 |
102,114,264 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1537:Lmo7
|
UTSW |
14 |
102,166,700 (GRCm39) |
utr 3 prime |
probably benign |
|
|
R1565:Lmo7
|
UTSW |
14 |
102,124,957 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R1637:Lmo7
|
UTSW |
14 |
102,118,268 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1943:Lmo7
|
UTSW |
14 |
102,139,738 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1967:Lmo7
|
UTSW |
14 |
102,137,651 (GRCm39) |
missense |
probably benign |
0.36 |
|
R2002:Lmo7
|
UTSW |
14 |
102,124,497 (GRCm39) |
missense |
probably benign |
0.13 |
|
R2057:Lmo7
|
UTSW |
14 |
102,124,614 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2131:Lmo7
|
UTSW |
14 |
102,137,674 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R2153:Lmo7
|
UTSW |
14 |
102,157,951 (GRCm39) |
utr 3 prime |
probably benign |
|
|
R2257:Lmo7
|
UTSW |
14 |
102,137,566 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2355:Lmo7
|
UTSW |
14 |
102,126,121 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2356:Lmo7
|
UTSW |
14 |
102,124,381 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2898:Lmo7
|
UTSW |
14 |
102,114,350 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R3847:Lmo7
|
UTSW |
14 |
102,159,531 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
R3848:Lmo7
|
UTSW |
14 |
102,159,531 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
R3849:Lmo7
|
UTSW |
14 |
102,159,531 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
R3916:Lmo7
|
UTSW |
14 |
102,166,778 (GRCm39) |
utr 3 prime |
probably benign |
|
|
R4050:Lmo7
|
UTSW |
14 |
102,139,713 (GRCm39) |
nonsense |
probably null |
|
|
R4326:Lmo7
|
UTSW |
14 |
102,137,510 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R4357:Lmo7
|
UTSW |
14 |
102,125,091 (GRCm39) |
missense |
probably null |
1.00 |
|
R4571:Lmo7
|
UTSW |
14 |
102,125,030 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R4658:Lmo7
|
UTSW |
14 |
102,124,393 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4857:Lmo7
|
UTSW |
14 |
102,124,784 (GRCm39) |
splice site |
probably null |
|
|
R5006:Lmo7
|
UTSW |
14 |
102,163,673 (GRCm39) |
utr 3 prime |
probably benign |
|
|
R5528:Lmo7
|
UTSW |
14 |
102,139,522 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5588:Lmo7
|
UTSW |
14 |
102,134,026 (GRCm39) |
splice site |
probably null |
|
|
R5644:Lmo7
|
UTSW |
14 |
102,166,772 (GRCm39) |
utr 3 prime |
probably benign |
|
|
R5650:Lmo7
|
UTSW |
14 |
102,136,110 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5737:Lmo7
|
UTSW |
14 |
102,124,672 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5832:Lmo7
|
UTSW |
14 |
102,121,649 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5966:Lmo7
|
UTSW |
14 |
102,137,938 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R6026:Lmo7
|
UTSW |
14 |
102,118,426 (GRCm39) |
missense |
probably benign |
0.04 |
|
R6072:Lmo7
|
UTSW |
14 |
102,166,772 (GRCm39) |
utr 3 prime |
probably benign |
|
|
R6158:Lmo7
|
UTSW |
14 |
102,137,573 (GRCm39) |
missense |
probably benign |
0.03 |
|
R6246:Lmo7
|
UTSW |
14 |
102,156,136 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6335:Lmo7
|
UTSW |
14 |
102,138,072 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6620:Lmo7
|
UTSW |
14 |
102,112,888 (GRCm39) |
missense |
probably benign |
0.29 |
|
R6658:Lmo7
|
UTSW |
14 |
102,148,281 (GRCm39) |
missense |
possibly damaging |
0.84 |
|
R6917:Lmo7
|
UTSW |
14 |
102,155,446 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7064:Lmo7
|
UTSW |
14 |
102,121,615 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7072:Lmo7
|
UTSW |
14 |
102,136,136 (GRCm39) |
critical splice donor site |
probably null |
|
|
R7121:Lmo7
|
UTSW |
14 |
102,124,471 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7136:Lmo7
|
UTSW |
14 |
102,157,975 (GRCm39) |
missense |
unknown |
|
|
R7196:Lmo7
|
UTSW |
14 |
102,133,936 (GRCm39) |
missense |
possibly damaging |
0.75 |
|
R7228:Lmo7
|
UTSW |
14 |
102,133,971 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7337:Lmo7
|
UTSW |
14 |
102,121,640 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R7341:Lmo7
|
UTSW |
14 |
102,122,948 (GRCm39) |
missense |
probably benign |
0.30 |
|
R7408:Lmo7
|
UTSW |
14 |
102,118,389 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7432:Lmo7
|
UTSW |
14 |
102,139,551 (GRCm39) |
missense |
probably benign |
0.42 |
|
R7470:Lmo7
|
UTSW |
14 |
102,138,040 (GRCm39) |
missense |
possibly damaging |
0.83 |
|
R7506:Lmo7
|
UTSW |
14 |
102,157,045 (GRCm39) |
missense |
unknown |
|
|
R7559:Lmo7
|
UTSW |
14 |
102,124,662 (GRCm39) |
nonsense |
probably null |
|
|
R7565:Lmo7
|
UTSW |
14 |
102,122,737 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R7788:Lmo7
|
UTSW |
14 |
102,136,012 (GRCm39) |
missense |
possibly damaging |
0.64 |
|
R8095:Lmo7
|
UTSW |
14 |
102,124,855 (GRCm39) |
missense |
possibly damaging |
0.88 |
|
R8100:Lmo7
|
UTSW |
14 |
102,137,899 (GRCm39) |
missense |
probably benign |
0.33 |
|
R8121:Lmo7
|
UTSW |
14 |
102,163,736 (GRCm39) |
missense |
unknown |
|
|
R8308:Lmo7
|
UTSW |
14 |
102,139,807 (GRCm39) |
critical splice donor site |
probably null |
|
|
R8371:Lmo7
|
UTSW |
14 |
102,124,444 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R8403:Lmo7
|
UTSW |
14 |
102,139,800 (GRCm39) |
missense |
probably benign |
0.03 |
|
R8690:Lmo7
|
UTSW |
14 |
102,168,644 (GRCm39) |
missense |
unknown |
|
|
R8778:Lmo7
|
UTSW |
14 |
102,156,655 (GRCm39) |
missense |
probably benign |
0.24 |
|
R8778:Lmo7
|
UTSW |
14 |
102,149,503 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R8822:Lmo7
|
UTSW |
14 |
102,121,610 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8849:Lmo7
|
UTSW |
14 |
102,163,543 (GRCm39) |
missense |
unknown |
|
|
R8923:Lmo7
|
UTSW |
14 |
102,137,679 (GRCm39) |
missense |
probably benign |
0.31 |
|
R9006:Lmo7
|
UTSW |
14 |
102,155,072 (GRCm39) |
small deletion |
probably benign |
|
|
R9135:Lmo7
|
UTSW |
14 |
102,118,297 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9154:Lmo7
|
UTSW |
14 |
102,122,743 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R9178:Lmo7
|
UTSW |
14 |
102,044,906 (GRCm39) |
nonsense |
probably null |
|
|
R9375:Lmo7
|
UTSW |
14 |
102,136,123 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R9428:Lmo7
|
UTSW |
14 |
102,155,076 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R9488:Lmo7
|
UTSW |
14 |
102,122,783 (GRCm39) |
missense |
possibly damaging |
0.85 |
|
R9493:Lmo7
|
UTSW |
14 |
102,137,907 (GRCm39) |
missense |
probably benign |
0.01 |
|
R9594:Lmo7
|
UTSW |
14 |
102,156,136 (GRCm39) |
missense |
probably null |
0.98 |
|
R9674:Lmo7
|
UTSW |
14 |
102,078,340 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9736:Lmo7
|
UTSW |
14 |
102,157,929 (GRCm39) |
missense |
unknown |
|
|
X0066:Lmo7
|
UTSW |
14 |
102,124,897 (GRCm39) |
missense |
probably damaging |
1.00 |
|
X0067:Lmo7
|
UTSW |
14 |
102,124,369 (GRCm39) |
splice site |
probably null |
|
|
Z1176:Lmo7
|
UTSW |
14 |
102,156,717 (GRCm39) |
missense |
probably benign |
0.00 |
|
Z1176:Lmo7
|
UTSW |
14 |
102,121,742 (GRCm39) |
missense |
probably damaging |
0.99 |
|
Z1176:Lmo7
|
UTSW |
14 |
102,166,664 (GRCm39) |
missense |
unknown |
|
|
Z1176:Lmo7
|
UTSW |
14 |
102,156,879 (GRCm39) |
missense |
unknown |
|
|
Z1177:Lmo7
|
UTSW |
14 |
102,135,993 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Z1177:Lmo7
|
UTSW |
14 |
102,133,954 (GRCm39) |
missense |
possibly damaging |
0.96 |
|
| Predicted Primers |
PCR Primer
(F):5'- CCAGCAGTGTAACGTGACTC -3'
(R):5'- CATGCACTCAAAAGGACTTGC -3'
Sequencing Primer
(F):5'- CAGCAGTGTAACGTGACTCATGTC -3'
(R):5'- GCACTCAAAAGGACTTGCTTTTC -3'
|
| Posted On |
2016-11-08 |
Incidental Mutation