Incidental Mutation 'R5645:Iqgap3'
| ID |
441040 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Iqgap3
|
| Ensembl Gene |
ENSMUSG00000028068 |
| Gene Name |
IQ motif containing GTPase activating protein 3 |
| Synonyms |
|
| MMRRC Submission |
043293-MU
|
| Accession Numbers |
|
| Essential gene? |
Possibly non essential
(E-score: 0.314)
|
| Stock # |
R5645 (G1)
|
| Quality Score |
225 |
|
Status
|
Not validated
|
| Chromosome |
3 |
| Chromosomal Location |
87989309-88028355 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
T to C
at 88025006 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Isoleucine to Threonine
at position 669
(I669T)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000142035
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000071812]
[ENSMUST00000194440]
|
| AlphaFold |
F8VQ29 |
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000071812
AA Change: I1567T
PolyPhen 2
Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)
|
| SMART Domains |
Protein: ENSMUSP00000071715
Gene: ENSMUSG00000028068
AA Change: I1567T
| Domain | Start | End | E-Value | Type |
|---|
|
CH
|
36 |
145 |
1.72e-14 |
SMART |
|
internal_repeat_2
|
197 |
249 |
1.75e-5 |
PROSPERO |
|
internal_repeat_1
|
209 |
418 |
1.31e-14 |
PROSPERO |
|
low complexity region
|
419 |
438 |
N/A |
INTRINSIC |
|
internal_repeat_1
|
446 |
651 |
1.31e-14 |
PROSPERO |
|
internal_repeat_2
|
600 |
652 |
1.75e-5 |
PROSPERO |
|
IQ
|
730 |
752 |
1.18e1 |
SMART |
|
IQ
|
760 |
782 |
3.76e-6 |
SMART |
|
IQ
|
790 |
812 |
3.08e-2 |
SMART |
|
IQ
|
820 |
842 |
1.72e0 |
SMART |
|
RasGAP
|
977 |
1330 |
1.74e-57 |
SMART |
|
Blast:RasGAP
|
1338 |
1422 |
1e-9 |
BLAST |
|
Pfam:RasGAP_C
|
1434 |
1555 |
2e-36 |
PFAM |
|
low complexity region
|
1591 |
1602 |
N/A |
INTRINSIC |
|
low complexity region
|
1615 |
1630 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000194440
AA Change: I669T
PolyPhen 2
Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)
|
| SMART Domains |
Protein: ENSMUSP00000142035
Gene: ENSMUSG00000028068
AA Change: I669T
| Domain | Start | End | E-Value | Type |
|---|
|
Blast:RasGAP
|
1 |
67 |
3e-30 |
BLAST |
|
RasGAP
|
79 |
432 |
1e-59 |
SMART |
|
Blast:RasGAP
|
440 |
524 |
5e-10 |
BLAST |
|
Pfam:RasGAP_C
|
535 |
660 |
5.7e-30 |
PFAM |
|
low complexity region
|
693 |
704 |
N/A |
INTRINSIC |
|
low complexity region
|
717 |
732 |
N/A |
INTRINSIC |
|
| Coding Region Coverage |
- 1x: 99.3%
- 3x: 98.7%
- 10x: 97.5%
- 20x: 95.9%
|
| Validation Efficiency |
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 73 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 1700102P08Rik |
A |
G |
9: 108,274,403 (GRCm39) |
I169V |
probably damaging |
Het |
| 4930503B20Rik |
C |
T |
3: 146,356,264 (GRCm39) |
E215K |
probably damaging |
Het |
| Abca6 |
T |
C |
11: 110,141,234 (GRCm39) |
E29G |
probably damaging |
Het |
| Acsm1 |
A |
G |
7: 119,239,920 (GRCm39) |
H288R |
probably damaging |
Het |
| Adamts12 |
A |
G |
15: 11,277,506 (GRCm39) |
T707A |
possibly damaging |
Het |
| Adcy2 |
C |
A |
13: 68,877,321 (GRCm39) |
|
probably null |
Het |
| Agbl4 |
A |
T |
4: 111,514,527 (GRCm39) |
I513F |
possibly damaging |
Het |
| Ak5 |
A |
T |
3: 152,361,670 (GRCm39) |
M84K |
possibly damaging |
Het |
| Akap1 |
T |
C |
11: 88,736,453 (GRCm39) |
T103A |
probably benign |
Het |
| Akap9 |
A |
G |
5: 4,100,590 (GRCm39) |
T2751A |
probably benign |
Het |
| Amer3 |
A |
T |
1: 34,627,462 (GRCm39) |
H567L |
possibly damaging |
Het |
| Ano6 |
A |
G |
15: 95,818,232 (GRCm39) |
Y325C |
probably benign |
Het |
| Apba2 |
A |
G |
7: 64,345,554 (GRCm39) |
E248G |
possibly damaging |
Het |
| Asap2 |
T |
A |
12: 21,315,983 (GRCm39) |
V967E |
probably damaging |
Het |
| Atosa |
T |
A |
9: 74,932,961 (GRCm39) |
V976E |
probably damaging |
Het |
| Boc |
A |
G |
16: 44,320,024 (GRCm39) |
V320A |
probably damaging |
Het |
| Car13 |
T |
A |
3: 14,710,180 (GRCm39) |
Y41N |
possibly damaging |
Het |
| Ccdc162 |
T |
C |
10: 41,428,352 (GRCm39) |
T1976A |
probably benign |
Het |
| Cep295 |
C |
A |
9: 15,246,404 (GRCm39) |
S684I |
possibly damaging |
Het |
| Cep295 |
A |
T |
9: 15,244,090 (GRCm39) |
H1455Q |
probably damaging |
Het |
| Cr2 |
G |
T |
1: 194,836,581 (GRCm39) |
H861N |
probably damaging |
Het |
| Cul5 |
T |
C |
9: 53,534,243 (GRCm39) |
I630V |
probably benign |
Het |
| Cyp2c37 |
G |
A |
19: 39,982,596 (GRCm39) |
V145I |
probably benign |
Het |
| Dnmt1 |
G |
A |
9: 20,833,443 (GRCm39) |
T500M |
probably damaging |
Het |
| Elp1 |
T |
C |
4: 56,776,920 (GRCm39) |
T626A |
possibly damaging |
Het |
| Fam161a |
T |
A |
11: 22,965,725 (GRCm39) |
I6N |
probably damaging |
Het |
| Fry |
T |
C |
5: 150,304,332 (GRCm39) |
V574A |
probably damaging |
Het |
| Glb1l3 |
G |
T |
9: 26,736,122 (GRCm39) |
L553I |
probably benign |
Het |
| Gm1123 |
T |
C |
9: 98,896,244 (GRCm39) |
D212G |
probably benign |
Het |
| Grin2a |
T |
A |
16: 9,810,090 (GRCm39) |
D103V |
probably damaging |
Het |
| Heg1 |
A |
G |
16: 33,527,333 (GRCm39) |
I98V |
probably benign |
Het |
| Hmcn2 |
C |
A |
2: 31,310,824 (GRCm39) |
T3356N |
possibly damaging |
Het |
| Hpf1 |
T |
G |
8: 61,349,834 (GRCm39) |
I154S |
possibly damaging |
Het |
| Ifnar2 |
A |
G |
16: 91,201,115 (GRCm39) |
D452G |
possibly damaging |
Het |
| Iqcc |
A |
T |
4: 129,510,320 (GRCm39) |
H398Q |
possibly damaging |
Het |
| Itgae |
A |
G |
11: 73,020,074 (GRCm39) |
T859A |
probably damaging |
Het |
| Kansl1l |
T |
C |
1: 66,840,503 (GRCm39) |
M266V |
probably benign |
Het |
| Kbtbd3 |
A |
G |
9: 4,331,426 (GRCm39) |
D600G |
possibly damaging |
Het |
| Klf13 |
G |
A |
7: 63,541,348 (GRCm39) |
|
probably benign |
Het |
| Kmt2d |
A |
G |
15: 98,742,278 (GRCm39) |
|
probably benign |
Het |
| Lama1 |
A |
G |
17: 68,109,943 (GRCm39) |
D2188G |
probably damaging |
Het |
| Leng8 |
A |
G |
7: 4,148,273 (GRCm39) |
T682A |
probably damaging |
Het |
| Mab21l4 |
T |
C |
1: 93,080,668 (GRCm39) |
T413A |
probably damaging |
Het |
| Mslnl |
G |
T |
17: 25,956,816 (GRCm39) |
G34V |
possibly damaging |
Het |
| Mycbp2 |
A |
T |
14: 103,426,044 (GRCm39) |
S2360R |
probably damaging |
Het |
| Mycbp2 |
C |
A |
14: 103,426,051 (GRCm39) |
|
probably null |
Het |
| Nkx2-2 |
T |
C |
2: 147,026,319 (GRCm39) |
T140A |
probably damaging |
Het |
| Or11h6 |
T |
C |
14: 50,880,524 (GRCm39) |
V262A |
probably benign |
Het |
| Or4c125 |
A |
T |
2: 89,170,049 (GRCm39) |
V199E |
possibly damaging |
Het |
| Oser1 |
C |
T |
2: 163,248,965 (GRCm39) |
R79H |
probably damaging |
Het |
| Pfas |
A |
G |
11: 68,881,958 (GRCm39) |
V909A |
probably damaging |
Het |
| Pkhd1l1 |
A |
G |
15: 44,396,388 (GRCm39) |
E1970G |
probably benign |
Het |
| Prph2 |
G |
T |
17: 47,221,593 (GRCm39) |
|
probably benign |
Het |
| Rusc2 |
G |
T |
4: 43,425,758 (GRCm39) |
A1288S |
probably benign |
Het |
| Scart2 |
G |
A |
7: 139,828,853 (GRCm39) |
V171I |
possibly damaging |
Het |
| Sdha |
A |
G |
13: 74,471,958 (GRCm39) |
|
probably null |
Het |
| Sec16a |
T |
G |
2: 26,329,907 (GRCm39) |
T703P |
probably benign |
Het |
| Senp7 |
T |
A |
16: 55,993,571 (GRCm39) |
N724K |
possibly damaging |
Het |
| Skint1 |
A |
G |
4: 111,882,699 (GRCm39) |
I248V |
probably benign |
Het |
| Slc9a5 |
T |
C |
8: 106,083,645 (GRCm39) |
V395A |
probably benign |
Het |
| Slco1a4 |
T |
C |
6: 141,780,385 (GRCm39) |
N135S |
possibly damaging |
Het |
| Sncaip |
A |
G |
18: 53,028,028 (GRCm39) |
I412M |
probably damaging |
Het |
| Tacc2 |
A |
T |
7: 130,225,781 (GRCm39) |
D841V |
possibly damaging |
Het |
| Tekt1 |
A |
T |
11: 72,242,663 (GRCm39) |
H281Q |
probably benign |
Het |
| Tex46 |
G |
T |
4: 136,340,228 (GRCm39) |
M104I |
probably benign |
Het |
| Tjp3 |
T |
C |
10: 81,114,454 (GRCm39) |
|
probably null |
Het |
| Treh |
A |
G |
9: 44,593,975 (GRCm39) |
Y154C |
probably damaging |
Het |
| Trim80 |
T |
A |
11: 115,337,611 (GRCm39) |
L428Q |
probably damaging |
Het |
| Trpm6 |
A |
G |
19: 18,830,968 (GRCm39) |
K1278E |
probably damaging |
Het |
| Tut4 |
G |
A |
4: 108,414,570 (GRCm39) |
R49H |
probably damaging |
Het |
| Usp34 |
T |
C |
11: 23,325,024 (GRCm39) |
M990T |
possibly damaging |
Het |
| Vps9d1 |
A |
G |
8: 123,974,487 (GRCm39) |
S267P |
probably benign |
Het |
| Ywhae |
T |
C |
11: 75,647,750 (GRCm39) |
M160T |
probably benign |
Het |
|
| Other mutations in Iqgap3 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL01016:Iqgap3
|
APN |
3 |
88,014,867 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01062:Iqgap3
|
APN |
3 |
88,017,429 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL01517:Iqgap3
|
APN |
3 |
88,016,703 (GRCm39) |
missense |
probably benign |
0.09 |
|
IGL01530:Iqgap3
|
APN |
3 |
88,019,610 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
IGL01658:Iqgap3
|
APN |
3 |
88,023,278 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
IGL02027:Iqgap3
|
APN |
3 |
87,994,649 (GRCm39) |
missense |
possibly damaging |
0.67 |
|
IGL02352:Iqgap3
|
APN |
3 |
88,009,267 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL02359:Iqgap3
|
APN |
3 |
88,009,267 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL02522:Iqgap3
|
APN |
3 |
88,015,705 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
IGL02717:Iqgap3
|
APN |
3 |
88,005,666 (GRCm39) |
missense |
probably benign |
0.01 |
|
IGL02971:Iqgap3
|
APN |
3 |
87,997,611 (GRCm39) |
missense |
probably benign |
0.30 |
|
IGL03079:Iqgap3
|
APN |
3 |
88,020,477 (GRCm39) |
missense |
probably benign |
|
|
IGL03240:Iqgap3
|
APN |
3 |
88,022,281 (GRCm39) |
missense |
probably benign |
0.00 |
|
adjutant
|
UTSW |
3 |
88,008,834 (GRCm39) |
missense |
possibly damaging |
0.51 |
|
Booster
|
UTSW |
3 |
88,020,435 (GRCm39) |
missense |
probably damaging |
0.99 |
|
peso_ligero
|
UTSW |
3 |
88,020,078 (GRCm39) |
frame shift |
probably null |
|
|
R0048:Iqgap3
|
UTSW |
3 |
88,023,256 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0048:Iqgap3
|
UTSW |
3 |
88,023,256 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0285:Iqgap3
|
UTSW |
3 |
88,004,297 (GRCm39) |
missense |
probably benign |
0.11 |
|
R0442:Iqgap3
|
UTSW |
3 |
88,023,266 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R0490:Iqgap3
|
UTSW |
3 |
88,021,363 (GRCm39) |
splice site |
probably benign |
|
|
R0569:Iqgap3
|
UTSW |
3 |
87,998,032 (GRCm39) |
splice site |
probably benign |
|
|
R0747:Iqgap3
|
UTSW |
3 |
88,014,810 (GRCm39) |
splice site |
probably benign |
|
|
R0843:Iqgap3
|
UTSW |
3 |
88,015,738 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R1260:Iqgap3
|
UTSW |
3 |
88,021,330 (GRCm39) |
missense |
probably benign |
|
|
R1465:Iqgap3
|
UTSW |
3 |
87,994,616 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R1465:Iqgap3
|
UTSW |
3 |
87,994,616 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R1544:Iqgap3
|
UTSW |
3 |
88,006,200 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1662:Iqgap3
|
UTSW |
3 |
88,005,708 (GRCm39) |
missense |
probably benign |
0.33 |
|
R1686:Iqgap3
|
UTSW |
3 |
88,015,663 (GRCm39) |
splice site |
probably benign |
|
|
R1748:Iqgap3
|
UTSW |
3 |
88,021,287 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R1836:Iqgap3
|
UTSW |
3 |
88,015,675 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1972:Iqgap3
|
UTSW |
3 |
87,991,235 (GRCm39) |
splice site |
probably null |
|
|
R1973:Iqgap3
|
UTSW |
3 |
87,991,235 (GRCm39) |
splice site |
probably null |
|
|
R2051:Iqgap3
|
UTSW |
3 |
88,027,474 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2314:Iqgap3
|
UTSW |
3 |
88,023,338 (GRCm39) |
missense |
probably benign |
0.01 |
|
R2352:Iqgap3
|
UTSW |
3 |
88,011,815 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R2857:Iqgap3
|
UTSW |
3 |
88,014,903 (GRCm39) |
nonsense |
probably null |
|
|
R2859:Iqgap3
|
UTSW |
3 |
88,014,903 (GRCm39) |
nonsense |
probably null |
|
|
R3435:Iqgap3
|
UTSW |
3 |
88,001,911 (GRCm39) |
missense |
probably benign |
0.00 |
|
R3522:Iqgap3
|
UTSW |
3 |
87,998,089 (GRCm39) |
missense |
probably null |
0.90 |
|
R4281:Iqgap3
|
UTSW |
3 |
88,006,167 (GRCm39) |
missense |
probably benign |
0.19 |
|
R4283:Iqgap3
|
UTSW |
3 |
88,006,167 (GRCm39) |
missense |
probably benign |
0.19 |
|
R4397:Iqgap3
|
UTSW |
3 |
88,011,665 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4414:Iqgap3
|
UTSW |
3 |
88,004,293 (GRCm39) |
missense |
probably benign |
|
|
R4660:Iqgap3
|
UTSW |
3 |
88,027,483 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4872:Iqgap3
|
UTSW |
3 |
88,020,435 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R4883:Iqgap3
|
UTSW |
3 |
88,014,842 (GRCm39) |
missense |
probably benign |
|
|
R4915:Iqgap3
|
UTSW |
3 |
88,008,834 (GRCm39) |
missense |
possibly damaging |
0.51 |
|
R5050:Iqgap3
|
UTSW |
3 |
87,997,493 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5130:Iqgap3
|
UTSW |
3 |
88,016,161 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R5151:Iqgap3
|
UTSW |
3 |
88,025,067 (GRCm39) |
missense |
possibly damaging |
0.58 |
|
R5706:Iqgap3
|
UTSW |
3 |
88,023,215 (GRCm39) |
missense |
probably benign |
0.03 |
|
R5748:Iqgap3
|
UTSW |
3 |
88,016,677 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5880:Iqgap3
|
UTSW |
3 |
88,024,509 (GRCm39) |
missense |
possibly damaging |
0.67 |
|
R5982:Iqgap3
|
UTSW |
3 |
87,998,899 (GRCm39) |
nonsense |
probably null |
|
|
R6006:Iqgap3
|
UTSW |
3 |
87,998,854 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R6026:Iqgap3
|
UTSW |
3 |
87,997,478 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6188:Iqgap3
|
UTSW |
3 |
88,006,200 (GRCm39) |
missense |
probably benign |
0.00 |
|
R6211:Iqgap3
|
UTSW |
3 |
87,998,822 (GRCm39) |
missense |
probably benign |
|
|
R6291:Iqgap3
|
UTSW |
3 |
87,997,037 (GRCm39) |
critical splice donor site |
probably null |
|
|
R6344:Iqgap3
|
UTSW |
3 |
87,989,401 (GRCm39) |
critical splice donor site |
probably null |
|
|
R6854:Iqgap3
|
UTSW |
3 |
88,004,258 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6875:Iqgap3
|
UTSW |
3 |
88,020,078 (GRCm39) |
frame shift |
probably null |
|
|
R6877:Iqgap3
|
UTSW |
3 |
88,020,078 (GRCm39) |
frame shift |
probably null |
|
|
R6958:Iqgap3
|
UTSW |
3 |
88,020,673 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R7008:Iqgap3
|
UTSW |
3 |
88,020,078 (GRCm39) |
frame shift |
probably null |
|
|
R7050:Iqgap3
|
UTSW |
3 |
88,006,220 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7144:Iqgap3
|
UTSW |
3 |
88,024,217 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7170:Iqgap3
|
UTSW |
3 |
88,009,370 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7288:Iqgap3
|
UTSW |
3 |
88,016,142 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7952:Iqgap3
|
UTSW |
3 |
88,005,677 (GRCm39) |
missense |
probably benign |
|
|
R8008:Iqgap3
|
UTSW |
3 |
88,016,770 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R8049:Iqgap3
|
UTSW |
3 |
88,011,609 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8176:Iqgap3
|
UTSW |
3 |
88,001,957 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R8190:Iqgap3
|
UTSW |
3 |
87,998,086 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R8772:Iqgap3
|
UTSW |
3 |
87,997,144 (GRCm39) |
missense |
probably benign |
0.05 |
|
R8878:Iqgap3
|
UTSW |
3 |
88,020,532 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8893:Iqgap3
|
UTSW |
3 |
87,997,193 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9072:Iqgap3
|
UTSW |
3 |
88,016,773 (GRCm39) |
missense |
|
|
|
R9072:Iqgap3
|
UTSW |
3 |
87,998,883 (GRCm39) |
missense |
probably benign |
|
|
R9073:Iqgap3
|
UTSW |
3 |
88,016,773 (GRCm39) |
missense |
|
|
|
R9337:Iqgap3
|
UTSW |
3 |
88,023,425 (GRCm39) |
critical splice donor site |
probably null |
|
|
R9489:Iqgap3
|
UTSW |
3 |
88,016,176 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9492:Iqgap3
|
UTSW |
3 |
88,016,176 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9593:Iqgap3
|
UTSW |
3 |
88,011,657 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9655:Iqgap3
|
UTSW |
3 |
88,016,728 (GRCm39) |
missense |
possibly damaging |
0.53 |
|
R9708:Iqgap3
|
UTSW |
3 |
88,016,176 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9709:Iqgap3
|
UTSW |
3 |
88,016,176 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9752:Iqgap3
|
UTSW |
3 |
88,016,176 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9753:Iqgap3
|
UTSW |
3 |
88,016,176 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9765:Iqgap3
|
UTSW |
3 |
88,017,361 (GRCm39) |
missense |
possibly damaging |
0.47 |
|
R9771:Iqgap3
|
UTSW |
3 |
88,016,176 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9772:Iqgap3
|
UTSW |
3 |
88,016,176 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Z1177:Iqgap3
|
UTSW |
3 |
87,996,278 (GRCm39) |
critical splice donor site |
probably null |
|
|
| Predicted Primers |
PCR Primer
(F):5'- TGAGAACAGCTTGGTGGACC -3'
(R):5'- TGCCTCCCAGTACAGAATTAAAG -3'
Sequencing Primer
(F):5'- TGGTGGACCACGCAAAAAGAC -3'
(R):5'- GTGGTCATTTACGCCACAGTACATG -3'
|
| Posted On |
2016-11-08 |
Incidental Mutation