Mutagenetix > Incidental Mutation

Incidental Mutation 'R5669:2700049A03Rik'

442526

Institutional Source

Beutler Lab

Gene Symbol

2700049A03Rik

Ensembl Gene

ENSMUSG00000034601

Gene Name

RIKEN cDNA 2700049A03 gene

Synonyms

talpid3

MMRRC Submission

043312-MU

Accession Numbers

Essential gene?

Essential (E-score: 1.000) question?

Stock #

R5669 (G1)

Quality Score

225

Status

Not validated

Chromosome

Chromosomal Location

71136848-71243303 bp(+) (GRCm38)

Type of Mutation

nonsense

DNA Base Change (assembly)

G to T at 71164546 bp (GRCm38)

Zygosity

Heterozygous

Amino Acid Change

Glutamic Acid to Stop codon at position 685 (E685*)

Ref Sequence

ENSEMBL: ENSMUSP00000118956 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000045907] [ENSMUST00000149564]

AlphaFold

E9PV87

Predicted Effect

probably null
Transcript: ENSMUST00000045907
AA Change: E685*

SMART Domains

Protein: ENSMUSP00000044701
Gene: ENSMUSG00000034601
AA Change: E685*

Domain	Start	End	E-Value	Type
Pfam:TALPID3	116	1351	N/A	PFAM

Predicted Effect

probably null
Transcript: ENSMUST00000149564
AA Change: E685*

SMART Domains

Protein: ENSMUSP00000118956
Gene: ENSMUSG00000034601
AA Change: E685*

Domain	Start	End	E-Value	Type
Pfam:TALPID3	116	1349	N/A	PFAM

Meta Mutation Damage Score

0.9755

Coding Region Coverage

1x: 99.3%
3x: 98.8%
10x: 97.5%
20x: 95.9%

Validation Efficiency

MGI Phenotype

FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene encodes a conserved centrosomal protein that functions in ciliogenesis and responds to hedgehog signaling. Mutations in this gene causes Joubert syndrome 23. Alternative splicing results in multiple transcript variants and protein isoforms. [provided by RefSeq, Aug 2016]
PHENOTYPE: Mice homozygous for a null allele die during organogenesis, lack cilia, and show randomized L-R patterning, face and neural tube defects, pericardial edema and hemorrhages. Mouse embryonic fibroblasts homozygous for a different null allele lack cilia and asymmetrical centriolar localization. [provided by MGI curators]

Allele List at MGI

All alleles(12) : Targeted, other(2) Gene trapped(10)

Other mutations in this stock

Total: 53 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
Akap9	T	A	5: 4,050,540 (GRCm38)	L2734*	probably null	Het
Aldh1a1	T	C	19: 20,610,920 (GRCm38)	I25T	probably damaging	Het
Astl	G	T	2: 127,347,279 (GRCm38)	R175L	probably damaging	Het
BC035947	A	T	1: 78,497,913 (GRCm38)	C661S	probably damaging	Het
Cd160	C	T	3: 96,808,898 (GRCm38)		probably benign	Het
Cdc42bpb	C	T	12: 111,302,013 (GRCm38)		probably null	Het
Cdip1	T	A	16: 4,768,815 (GRCm38)	I149F	probably damaging	Het
Cfap65	T	C	1: 74,924,968 (GRCm38)	Y607C	probably damaging	Het
Col6a5	A	G	9: 105,925,998 (GRCm38)	I1256T	unknown	Het
Copb1	A	G	7: 114,237,585 (GRCm38)	V336A	probably damaging	Het
Ddx42	A	T	11: 106,241,819 (GRCm38)	D556V	probably damaging	Het
Dlk1	T	C	12: 109,460,038 (GRCm38)	V279A	probably benign	Het
Fbll1	T	C	11: 35,797,584 (GRCm38)	N284S	probably benign	Het
Fbxw21	A	T	9: 109,145,510 (GRCm38)	I314N	probably benign	Het
Foxa3	T	C	7: 19,014,251 (GRCm38)	T317A	probably benign	Het
Gm14139	A	G	2: 150,192,178 (GRCm38)	I140V	probably benign	Het
Gpr37	A	T	6: 25,669,352 (GRCm38)	C498S	probably benign	Het
Hapln3	G	T	7: 79,117,496 (GRCm38)		probably null	Het
Igkv4-54	A	G	6: 69,631,848 (GRCm38)	V29A	possibly damaging	Het
Itgb8	T	A	12: 119,190,628 (GRCm38)	I225F	probably damaging	Het
Kcnk3	A	G	5: 30,622,349 (GRCm38)	T248A	probably damaging	Het
Kcnv1	T	C	15: 45,114,252 (GRCm38)	Q130R	possibly damaging	Het
Lrp1b	T	C	2: 41,111,038 (GRCm38)	H2058R	probably damaging	Het
Macf1	T	A	4: 123,476,225 (GRCm38)	E1581V	probably damaging	Het
Mga	A	G	2: 119,903,426 (GRCm38)	N252D	probably damaging	Het
Nadsyn1	C	T	7: 143,807,431 (GRCm38)	G335S	probably damaging	Het
Olfr1115	T	C	2: 87,252,441 (GRCm38)	V168A	probably benign	Het
Olfr58	T	C	9: 19,783,757 (GRCm38)	F208S	probably benign	Het
Pak7	G	A	2: 136,116,284 (GRCm38)	P295S	probably damaging	Het
Pcsk1	T	A	13: 75,130,102 (GRCm38)	S595T	probably benign	Het
Pepd	T	C	7: 35,040,674 (GRCm38)	V324A	probably benign	Het
Pml	C	T	9: 58,247,063 (GRCm38)	D176N	probably benign	Het
Popdc3	T	A	10: 45,316,433 (GRCm38)	I163N	probably damaging	Het
Ppp1r13l	A	C	7: 19,373,022 (GRCm38)	T481P	probably benign	Het
Pramef12	T	C	4: 144,395,843 (GRCm38)	I44V	probably benign	Het
Prlh	A	G	1: 90,953,120 (GRCm38)	T5A	probably benign	Het
Prom1	A	G	5: 44,012,943 (GRCm38)	F638S	possibly damaging	Het
Prpf8	T	A	11: 75,504,738 (GRCm38)	L1897H	probably damaging	Het
Ret	T	C	6: 118,184,243 (GRCm38)	T91A	probably benign	Het
Retsat	A	G	6: 72,606,010 (GRCm38)	S176G	probably benign	Het
Rnd2	C	T	11: 101,468,999 (GRCm38)	L57F	probably damaging	Het
Rnf213	T	C	11: 119,458,785 (GRCm38)	L3823P	possibly damaging	Het
Rnf31	C	T	14: 55,596,704 (GRCm38)	A653V	probably damaging	Het
Rps6kl1	T	C	12: 85,147,867 (GRCm38)	D90G	probably damaging	Het
Scarb1	A	G	5: 125,300,387 (GRCm38)	Y194H	probably damaging	Het
Scube2	C	T	7: 109,825,439 (GRCm38)	A556T	probably benign	Het
Serpinb1a	A	G	13: 32,845,316 (GRCm38)	L243P	probably damaging	Het
Slc39a4	A	C	15: 76,614,163 (GRCm38)	L358R	probably damaging	Het
Slitrk5	A	G	14: 111,681,623 (GRCm38)	D893G	probably damaging	Het
Srgap1	C	A	10: 121,804,850 (GRCm38)	V681L	probably benign	Het
Tmprss6	A	T	15: 78,454,956 (GRCm38)	M262K	possibly damaging	Het
Ttf2	T	A	3: 100,951,117 (GRCm38)	K719*	probably null	Het
Vmn1r62	T	A	7: 5,675,737 (GRCm38)	L139*	probably null	Het

Other mutations in 2700049A03Rik

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00339:2700049A03Rik	APN	12	71,167,119 (GRCm38)	missense	probably benign	0.00
IGL01107:2700049A03Rik	APN	12	71,194,468 (GRCm38)	critical splice donor site	probably null
IGL01404:2700049A03Rik	APN	12	71,164,378 (GRCm38)	splice site	probably null
IGL01835:2700049A03Rik	APN	12	71,167,183 (GRCm38)	missense	probably benign	0.00
IGL01835:2700049A03Rik	APN	12	71,167,181 (GRCm38)	nonsense	probably null
IGL02122:2700049A03Rik	APN	12	71,170,525 (GRCm38)	missense	possibly damaging	0.93
IGL02140:2700049A03Rik	APN	12	71,148,260 (GRCm38)	missense	probably benign	0.06
IGL02385:2700049A03Rik	APN	12	71,154,856 (GRCm38)	missense	probably damaging	0.98
IGL03181:2700049A03Rik	APN	12	71,193,373 (GRCm38)	missense	possibly damaging	0.51
IGL03253:2700049A03Rik	APN	12	71,140,883 (GRCm38)	missense	probably benign	0.33
IGL03278:2700049A03Rik	APN	12	71,158,825 (GRCm38)	splice site	probably benign
G4846:2700049A03Rik	UTSW	12	71,137,909 (GRCm38)	missense	probably benign
PIT1430001:2700049A03Rik	UTSW	12	71,160,386 (GRCm38)	missense	possibly damaging	0.71
PIT4519001:2700049A03Rik	UTSW	12	71,170,666 (GRCm38)	missense	probably benign	0.05
R0108:2700049A03Rik	UTSW	12	71,177,918 (GRCm38)	missense	probably benign	0.14
R0165:2700049A03Rik	UTSW	12	71,167,150 (GRCm38)	missense	possibly damaging	0.52
R0211:2700049A03Rik	UTSW	12	71,216,096 (GRCm38)	missense	possibly damaging	0.96
R0211:2700049A03Rik	UTSW	12	71,216,096 (GRCm38)	missense	possibly damaging	0.96
R0220:2700049A03Rik	UTSW	12	71,148,420 (GRCm38)	critical splice donor site	probably null
R0352:2700049A03Rik	UTSW	12	71,138,030 (GRCm38)	missense	possibly damaging	0.96
R0468:2700049A03Rik	UTSW	12	71,193,310 (GRCm38)	missense	possibly damaging	0.71
R0508:2700049A03Rik	UTSW	12	71,164,388 (GRCm38)	missense	probably damaging	0.98
R0673:2700049A03Rik	UTSW	12	71,177,868 (GRCm38)	missense	probably damaging	0.97
R0840:2700049A03Rik	UTSW	12	71,158,883 (GRCm38)	missense	probably benign	0.16
R0893:2700049A03Rik	UTSW	12	71,219,308 (GRCm38)	splice site	probably benign
R1244:2700049A03Rik	UTSW	12	71,216,144 (GRCm38)	missense	probably benign	0.25
R1432:2700049A03Rik	UTSW	12	71,170,587 (GRCm38)	splice site	probably null
R1599:2700049A03Rik	UTSW	12	71,150,259 (GRCm38)	missense	probably damaging	0.98
R1732:2700049A03Rik	UTSW	12	71,219,221 (GRCm38)	missense	probably benign	0.18
R1820:2700049A03Rik	UTSW	12	71,150,244 (GRCm38)	missense	possibly damaging	0.51
R1939:2700049A03Rik	UTSW	12	71,160,412 (GRCm38)	splice site	probably null
R1998:2700049A03Rik	UTSW	12	71,188,619 (GRCm38)	missense	possibly damaging	0.86
R2337:2700049A03Rik	UTSW	12	71,164,547 (GRCm38)	missense	possibly damaging	0.93
R2337:2700049A03Rik	UTSW	12	71,164,546 (GRCm38)	nonsense	probably null
R2340:2700049A03Rik	UTSW	12	71,164,547 (GRCm38)	missense	possibly damaging	0.93
R2340:2700049A03Rik	UTSW	12	71,164,546 (GRCm38)	nonsense	probably null
R2382:2700049A03Rik	UTSW	12	71,164,547 (GRCm38)	missense	possibly damaging	0.93
R2382:2700049A03Rik	UTSW	12	71,164,546 (GRCm38)	nonsense	probably null
R2384:2700049A03Rik	UTSW	12	71,164,547 (GRCm38)	missense	possibly damaging	0.93
R2384:2700049A03Rik	UTSW	12	71,164,546 (GRCm38)	nonsense	probably null
R2445:2700049A03Rik	UTSW	12	71,164,547 (GRCm38)	missense	possibly damaging	0.93
R2445:2700049A03Rik	UTSW	12	71,164,546 (GRCm38)	nonsense	probably null
R2449:2700049A03Rik	UTSW	12	71,164,547 (GRCm38)	missense	possibly damaging	0.93
R2449:2700049A03Rik	UTSW	12	71,164,546 (GRCm38)	nonsense	probably null
R2512:2700049A03Rik	UTSW	12	71,173,171 (GRCm38)	missense	possibly damaging	0.71
R2872:2700049A03Rik	UTSW	12	71,154,756 (GRCm38)	splice site	probably benign
R3236:2700049A03Rik	UTSW	12	71,164,547 (GRCm38)	missense	possibly damaging	0.93
R3236:2700049A03Rik	UTSW	12	71,164,546 (GRCm38)	nonsense	probably null
R3237:2700049A03Rik	UTSW	12	71,164,547 (GRCm38)	missense	possibly damaging	0.93
R3237:2700049A03Rik	UTSW	12	71,164,546 (GRCm38)	nonsense	probably null
R3734:2700049A03Rik	UTSW	12	71,164,547 (GRCm38)	missense	possibly damaging	0.93
R3734:2700049A03Rik	UTSW	12	71,164,546 (GRCm38)	nonsense	probably null
R3808:2700049A03Rik	UTSW	12	71,164,546 (GRCm38)	nonsense	probably null
R3808:2700049A03Rik	UTSW	12	71,164,547 (GRCm38)	missense	possibly damaging	0.93
R3809:2700049A03Rik	UTSW	12	71,164,546 (GRCm38)	nonsense	probably null
R3809:2700049A03Rik	UTSW	12	71,164,547 (GRCm38)	missense	possibly damaging	0.93
R3944:2700049A03Rik	UTSW	12	71,164,546 (GRCm38)	nonsense	probably null
R3944:2700049A03Rik	UTSW	12	71,164,547 (GRCm38)	missense	possibly damaging	0.93
R3959:2700049A03Rik	UTSW	12	71,164,546 (GRCm38)	nonsense	probably null
R3959:2700049A03Rik	UTSW	12	71,164,547 (GRCm38)	missense	possibly damaging	0.93
R3960:2700049A03Rik	UTSW	12	71,164,546 (GRCm38)	nonsense	probably null
R3960:2700049A03Rik	UTSW	12	71,164,547 (GRCm38)	missense	possibly damaging	0.93
R4593:2700049A03Rik	UTSW	12	71,164,546 (GRCm38)	nonsense	probably null
R4593:2700049A03Rik	UTSW	12	71,164,547 (GRCm38)	missense	possibly damaging	0.93
R4595:2700049A03Rik	UTSW	12	71,164,546 (GRCm38)	nonsense	probably null
R4595:2700049A03Rik	UTSW	12	71,164,547 (GRCm38)	missense	possibly damaging	0.93
R4596:2700049A03Rik	UTSW	12	71,164,546 (GRCm38)	nonsense	probably null
R4596:2700049A03Rik	UTSW	12	71,164,547 (GRCm38)	missense	possibly damaging	0.93
R4600:2700049A03Rik	UTSW	12	71,148,263 (GRCm38)	missense	possibly damaging	0.67
R4649:2700049A03Rik	UTSW	12	71,164,546 (GRCm38)	nonsense	probably null
R4649:2700049A03Rik	UTSW	12	71,164,547 (GRCm38)	missense	possibly damaging	0.93
R4651:2700049A03Rik	UTSW	12	71,164,547 (GRCm38)	missense	possibly damaging	0.93
R4651:2700049A03Rik	UTSW	12	71,164,546 (GRCm38)	nonsense	probably null
R4652:2700049A03Rik	UTSW	12	71,164,547 (GRCm38)	missense	possibly damaging	0.93
R4652:2700049A03Rik	UTSW	12	71,164,546 (GRCm38)	nonsense	probably null
R4714:2700049A03Rik	UTSW	12	71,164,547 (GRCm38)	missense	possibly damaging	0.93
R4714:2700049A03Rik	UTSW	12	71,164,546 (GRCm38)	nonsense	probably null
R4735:2700049A03Rik	UTSW	12	71,216,123 (GRCm38)	missense	possibly damaging	0.88
R4810:2700049A03Rik	UTSW	12	71,189,442 (GRCm38)	missense	possibly damaging	0.51
R4852:2700049A03Rik	UTSW	12	71,164,547 (GRCm38)	missense	possibly damaging	0.93
R4852:2700049A03Rik	UTSW	12	71,164,546 (GRCm38)	nonsense	probably null
R4854:2700049A03Rik	UTSW	12	71,164,547 (GRCm38)	missense	possibly damaging	0.93
R4854:2700049A03Rik	UTSW	12	71,164,546 (GRCm38)	nonsense	probably null
R4855:2700049A03Rik	UTSW	12	71,164,546 (GRCm38)	nonsense	probably null
R4855:2700049A03Rik	UTSW	12	71,164,547 (GRCm38)	missense	possibly damaging	0.93
R4884:2700049A03Rik	UTSW	12	71,164,546 (GRCm38)	nonsense	probably null
R4884:2700049A03Rik	UTSW	12	71,164,547 (GRCm38)	missense	possibly damaging	0.93
R4893:2700049A03Rik	UTSW	12	71,164,546 (GRCm38)	nonsense	probably null
R4893:2700049A03Rik	UTSW	12	71,164,547 (GRCm38)	missense	possibly damaging	0.93
R4905:2700049A03Rik	UTSW	12	71,164,546 (GRCm38)	nonsense	probably null
R4905:2700049A03Rik	UTSW	12	71,164,547 (GRCm38)	missense	possibly damaging	0.93
R4915:2700049A03Rik	UTSW	12	71,189,646 (GRCm38)	missense	possibly damaging	0.92
R4919:2700049A03Rik	UTSW	12	71,164,546 (GRCm38)	nonsense	probably null
R4919:2700049A03Rik	UTSW	12	71,164,547 (GRCm38)	missense	possibly damaging	0.93
R4959:2700049A03Rik	UTSW	12	71,164,546 (GRCm38)	nonsense	probably null
R4959:2700049A03Rik	UTSW	12	71,164,547 (GRCm38)	missense	possibly damaging	0.93
R4989:2700049A03Rik	UTSW	12	71,164,546 (GRCm38)	nonsense	probably null
R4989:2700049A03Rik	UTSW	12	71,164,547 (GRCm38)	missense	possibly damaging	0.93
R5011:2700049A03Rik	UTSW	12	71,164,546 (GRCm38)	nonsense	probably null
R5011:2700049A03Rik	UTSW	12	71,164,547 (GRCm38)	missense	possibly damaging	0.93
R5012:2700049A03Rik	UTSW	12	71,164,546 (GRCm38)	nonsense	probably null
R5012:2700049A03Rik	UTSW	12	71,164,547 (GRCm38)	missense	possibly damaging	0.93
R5118:2700049A03Rik	UTSW	12	71,164,546 (GRCm38)	nonsense	probably null
R5118:2700049A03Rik	UTSW	12	71,164,547 (GRCm38)	missense	possibly damaging	0.93
R5146:2700049A03Rik	UTSW	12	71,243,025 (GRCm38)	missense	possibly damaging	0.85
R5163:2700049A03Rik	UTSW	12	71,164,546 (GRCm38)	nonsense	probably null
R5163:2700049A03Rik	UTSW	12	71,164,547 (GRCm38)	missense	possibly damaging	0.93
R5188:2700049A03Rik	UTSW	12	71,164,546 (GRCm38)	nonsense	probably null
R5188:2700049A03Rik	UTSW	12	71,164,547 (GRCm38)	missense	possibly damaging	0.93
R5189:2700049A03Rik	UTSW	12	71,164,546 (GRCm38)	nonsense	probably null
R5189:2700049A03Rik	UTSW	12	71,164,547 (GRCm38)	missense	possibly damaging	0.93
R5189:2700049A03Rik	UTSW	12	71,193,349 (GRCm38)	missense	possibly damaging	0.93
R5190:2700049A03Rik	UTSW	12	71,164,546 (GRCm38)	nonsense	probably null
R5190:2700049A03Rik	UTSW	12	71,164,547 (GRCm38)	missense	possibly damaging	0.93
R5290:2700049A03Rik	UTSW	12	71,188,791 (GRCm38)	missense	probably benign	0.00
R5344:2700049A03Rik	UTSW	12	71,243,027 (GRCm38)	missense	probably benign
R5502:2700049A03Rik	UTSW	12	71,164,547 (GRCm38)	missense	possibly damaging	0.93
R5502:2700049A03Rik	UTSW	12	71,164,546 (GRCm38)	nonsense	probably null
R5503:2700049A03Rik	UTSW	12	71,164,547 (GRCm38)	missense	possibly damaging	0.93
R5503:2700049A03Rik	UTSW	12	71,164,546 (GRCm38)	nonsense	probably null
R5619:2700049A03Rik	UTSW	12	71,164,547 (GRCm38)	missense	possibly damaging	0.93
R5619:2700049A03Rik	UTSW	12	71,164,546 (GRCm38)	nonsense	probably null
R5667:2700049A03Rik	UTSW	12	71,164,547 (GRCm38)	missense	possibly damaging	0.93
R5667:2700049A03Rik	UTSW	12	71,164,546 (GRCm38)	nonsense	probably null
R5669:2700049A03Rik	UTSW	12	71,164,547 (GRCm38)	missense	possibly damaging	0.93
R5671:2700049A03Rik	UTSW	12	71,164,547 (GRCm38)	missense	possibly damaging	0.93
R5671:2700049A03Rik	UTSW	12	71,164,546 (GRCm38)	nonsense	probably null
R5725:2700049A03Rik	UTSW	12	71,193,319 (GRCm38)	missense	probably benign	0.05
R5956:2700049A03Rik	UTSW	12	71,157,119 (GRCm38)	missense	possibly damaging	0.86
R6051:2700049A03Rik	UTSW	12	71,184,530 (GRCm38)	missense	possibly damaging	0.84
R6148:2700049A03Rik	UTSW	12	71,187,426 (GRCm38)	missense	possibly damaging	0.71
R6158:2700049A03Rik	UTSW	12	71,170,636 (GRCm38)	missense	possibly damaging	0.51
R6916:2700049A03Rik	UTSW	12	71,164,544 (GRCm38)	missense	possibly damaging	0.86
R7129:2700049A03Rik	UTSW	12	71,216,230 (GRCm38)	splice site	probably null
R7168:2700049A03Rik	UTSW	12	71,216,057 (GRCm38)	missense	probably damaging	0.98
R7193:2700049A03Rik	UTSW	12	71,219,189 (GRCm38)	critical splice acceptor site	probably null
R7200:2700049A03Rik	UTSW	12	71,140,906 (GRCm38)	missense	probably damaging	0.96
R7359:2700049A03Rik	UTSW	12	71,189,574 (GRCm38)	missense	possibly damaging	0.51
R7488:2700049A03Rik	UTSW	12	71,150,405 (GRCm38)	missense	possibly damaging	0.67
R7755:2700049A03Rik	UTSW	12	71,189,413 (GRCm38)	missense	probably benign	0.02
R7757:2700049A03Rik	UTSW	12	71,189,413 (GRCm38)	missense	probably benign	0.02
R7922:2700049A03Rik	UTSW	12	71,164,406 (GRCm38)	missense	possibly damaging	0.83
R7966:2700049A03Rik	UTSW	12	71,173,129 (GRCm38)	missense	probably benign	0.00
R8082:2700049A03Rik	UTSW	12	71,142,121 (GRCm38)	critical splice donor site	probably null
R8311:2700049A03Rik	UTSW	12	71,138,041 (GRCm38)	unclassified	probably benign
R8408:2700049A03Rik	UTSW	12	71,189,582 (GRCm38)	missense	possibly damaging	0.71
R8852:2700049A03Rik	UTSW	12	71,184,423 (GRCm38)	missense	possibly damaging	0.93
R8860:2700049A03Rik	UTSW	12	71,184,423 (GRCm38)	missense	possibly damaging	0.93
R9039:2700049A03Rik	UTSW	12	71,167,075 (GRCm38)	missense	possibly damaging	0.51
R9281:2700049A03Rik	UTSW	12	71,158,913 (GRCm38)	missense	possibly damaging	0.51
R9308:2700049A03Rik	UTSW	12	71,184,459 (GRCm38)	missense	probably benign	0.23
R9385:2700049A03Rik	UTSW	12	71,161,192 (GRCm38)	missense	possibly damaging	0.52
R9412:2700049A03Rik	UTSW	12	71,188,683 (GRCm38)	missense	possibly damaging	0.71
R9643:2700049A03Rik	UTSW	12	71,164,415 (GRCm38)	missense	possibly damaging	0.92
R9676:2700049A03Rik	UTSW	12	71,161,131 (GRCm38)	missense	possibly damaging	0.86
R9776:2700049A03Rik	UTSW	12	71,188,674 (GRCm38)	missense	possibly damaging	0.71
R9789:2700049A03Rik	UTSW	12	71,184,583 (GRCm38)	missense	probably benign
Z1177:2700049A03Rik	UTSW	12	71,164,484 (GRCm38)	missense	probably damaging	1.00

Predicted Primers

PCR Primer
(F):5'- AAGACCTTTTATGTTTCCTAGGTGG -3'
(R):5'- TGTTCCCTGGCAGATAACGG -3'

Sequencing Primer
(F):5'- AACATGTTTTGCATTGGTAGGGCC -3'
(R):5'- TAACGGTACTGAAGCTCTGC -3'

Posted On

2016-11-09