Incidental Mutation 'R0544:Myom2'
| ID |
44691 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Myom2
|
| Ensembl Gene |
ENSMUSG00000031461 |
| Gene Name |
myomesin 2 |
| Synonyms |
|
| MMRRC Submission |
038736-MU
|
| Accession Numbers |
|
| Essential gene? |
Probably non essential
(E-score: 0.148)
|
| Stock # |
R0544 (G1)
|
| Quality Score |
225 |
|
Status
|
Validated
|
| Chromosome |
8 |
| Chromosomal Location |
15107653-15183410 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
T to A
at 15119796 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Valine to Glutamic Acid
at position 184
(V184E)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000033842
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000033842]
|
| AlphaFold |
Q14BI5 |
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000033842
AA Change: V184E
PolyPhen 2
Score 0.999 (Sensitivity: 0.14; Specificity: 0.99)
|
| SMART Domains |
Protein: ENSMUSP00000033842
Gene: ENSMUSG00000031461
AA Change: V184E
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
34 |
63 |
N/A |
INTRINSIC |
|
low complexity region
|
79 |
87 |
N/A |
INTRINSIC |
|
coiled coil region
|
97 |
129 |
N/A |
INTRINSIC |
|
IG
|
160 |
247 |
7.7e-5 |
SMART |
|
IG
|
284 |
373 |
8.01e-3 |
SMART |
|
FN3
|
383 |
466 |
1.5e-14 |
SMART |
|
FN3
|
511 |
594 |
1.79e-12 |
SMART |
|
FN3
|
612 |
693 |
1.95e-13 |
SMART |
|
FN3
|
711 |
794 |
8.69e-11 |
SMART |
|
FN3
|
813 |
896 |
1.86e-10 |
SMART |
|
IG_like
|
913 |
999 |
1.58e2 |
SMART |
|
Blast:IG_like
|
1021 |
1106 |
1e-44 |
BLAST |
|
IG_like
|
1135 |
1215 |
2.27e1 |
SMART |
|
Blast:IG_like
|
1227 |
1321 |
9e-51 |
BLAST |
|
IGc2
|
1357 |
1425 |
4.96e-8 |
SMART |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000131251
|
| Meta Mutation Damage Score |
0.4452 |
| Coding Region Coverage |
- 1x: 99.2%
- 3x: 98.6%
- 10x: 97.0%
- 20x: 94.6%
|
| Validation Efficiency |
98% (97/99) |
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] The giant protein titin, together with its associated proteins, interconnects the major structure of sarcomeres, the M bands and Z discs. The C-terminal end of the titin string extends into the M line, where it binds tightly to M-band constituents of apparent molecular masses of 190 kD and 165 kD. The predicted MYOM2 protein contains 1,465 amino acids. Like MYOM1, MYOM2 has a unique N-terminal domain followed by 12 repeat domains with strong homology to either fibronectin type III or immunoglobulin C2 domains. Protein sequence comparisons suggested that the MYOM2 protein and bovine M protein are identical. [provided by RefSeq, Jul 2008]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 97 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 9930012K11Rik |
A |
T |
14: 70,394,763 (GRCm39) |
F130L |
probably benign |
Het |
| Aatf |
C |
T |
11: 84,313,831 (GRCm39) |
R511Q |
probably benign |
Het |
| Acot12 |
A |
T |
13: 91,932,775 (GRCm39) |
D516V |
probably benign |
Het |
| Adgrb2 |
T |
C |
4: 129,911,335 (GRCm39) |
V1207A |
probably damaging |
Het |
| Akap9 |
A |
G |
5: 4,119,185 (GRCm39) |
D3564G |
probably benign |
Het |
| Arl8b |
C |
T |
6: 108,760,189 (GRCm39) |
|
probably benign |
Het |
| Atf6b |
T |
C |
17: 34,867,273 (GRCm39) |
|
probably null |
Het |
| Atrn |
G |
A |
2: 130,828,746 (GRCm39) |
G1097D |
probably damaging |
Het |
| Btbd6 |
A |
G |
12: 112,940,702 (GRCm39) |
E61G |
probably damaging |
Het |
| Car15 |
A |
G |
16: 17,653,680 (GRCm39) |
|
probably benign |
Het |
| Car5b |
G |
A |
X: 162,762,297 (GRCm39) |
R282C |
probably damaging |
Het |
| Carmil2 |
C |
T |
8: 106,417,867 (GRCm39) |
A654V |
probably damaging |
Het |
| Ccdc88b |
A |
G |
19: 6,834,634 (GRCm39) |
L124P |
probably damaging |
Het |
| Ccnd1 |
A |
G |
7: 144,491,023 (GRCm39) |
|
probably benign |
Het |
| Cenph |
A |
G |
13: 100,909,249 (GRCm39) |
S53P |
probably damaging |
Het |
| Chrm3 |
T |
A |
13: 9,927,615 (GRCm39) |
I474F |
probably damaging |
Het |
| Cln8 |
T |
A |
8: 14,946,769 (GRCm39) |
V261E |
probably benign |
Het |
| Coa6 |
A |
G |
8: 127,149,499 (GRCm39) |
D25G |
probably benign |
Het |
| Col4a1 |
T |
G |
8: 11,276,487 (GRCm39) |
|
probably benign |
Het |
| Cpxm1 |
T |
C |
2: 130,235,055 (GRCm39) |
H588R |
probably damaging |
Het |
| Cul7 |
T |
C |
17: 46,974,470 (GRCm39) |
L1516P |
possibly damaging |
Het |
| Dcdc5 |
A |
G |
2: 106,181,909 (GRCm39) |
|
noncoding transcript |
Het |
| Ddx5 |
T |
C |
11: 106,673,288 (GRCm39) |
|
probably benign |
Het |
| Dhx16 |
C |
A |
17: 36,192,551 (GRCm39) |
P161Q |
probably benign |
Het |
| Dpy19l1 |
A |
T |
9: 24,396,406 (GRCm39) |
|
probably benign |
Het |
| Fastkd5 |
A |
G |
2: 130,457,216 (GRCm39) |
V458A |
probably damaging |
Het |
| Fhit |
A |
G |
14: 9,870,172 (GRCm38) |
V99A |
probably damaging |
Het |
| Fndc3a |
A |
T |
14: 72,795,062 (GRCm39) |
|
probably benign |
Het |
| Foxd4 |
A |
T |
19: 24,877,182 (GRCm39) |
S339R |
possibly damaging |
Het |
| Gm10842 |
T |
A |
11: 105,037,880 (GRCm39) |
D54E |
unknown |
Het |
| Gns |
T |
A |
10: 121,212,172 (GRCm39) |
Y94* |
probably null |
Het |
| Gp2 |
A |
G |
7: 119,053,719 (GRCm39) |
W81R |
probably benign |
Het |
| Hdac5 |
T |
G |
11: 102,086,922 (GRCm39) |
Q46P |
probably damaging |
Het |
| Homer2 |
A |
C |
7: 81,299,426 (GRCm39) |
V13G |
probably damaging |
Het |
| Irs3 |
A |
G |
5: 137,642,101 (GRCm39) |
S446P |
probably benign |
Het |
| Ism2 |
G |
T |
12: 87,332,113 (GRCm39) |
D141E |
probably damaging |
Het |
| Jak1 |
T |
A |
4: 101,048,822 (GRCm39) |
M19L |
probably benign |
Het |
| Kcnd3 |
C |
A |
3: 105,566,075 (GRCm39) |
R419S |
probably damaging |
Het |
| Lamb1 |
T |
C |
12: 31,332,694 (GRCm39) |
F272S |
probably damaging |
Het |
| Ldlrad2 |
T |
G |
4: 137,299,579 (GRCm39) |
T82P |
possibly damaging |
Het |
| Lrp2 |
T |
C |
2: 69,322,275 (GRCm39) |
K1885E |
probably benign |
Het |
| Mbd5 |
T |
C |
2: 49,147,221 (GRCm39) |
V477A |
possibly damaging |
Het |
| Mrps33 |
A |
T |
6: 39,782,488 (GRCm39) |
M11K |
possibly damaging |
Het |
| Mylk |
G |
C |
16: 34,699,845 (GRCm39) |
E403Q |
possibly damaging |
Het |
| Ncor1 |
C |
A |
11: 62,224,602 (GRCm39) |
G1210V |
probably damaging |
Het |
| Ncor1 |
C |
T |
11: 62,224,603 (GRCm39) |
G1210R |
probably damaging |
Het |
| Nlrp4a |
A |
G |
7: 26,156,555 (GRCm39) |
D760G |
probably benign |
Het |
| Noc4l |
A |
G |
5: 110,798,989 (GRCm39) |
V231A |
possibly damaging |
Het |
| Or2at1 |
T |
C |
7: 99,416,867 (GRCm39) |
I166T |
probably benign |
Het |
| Or4c112 |
T |
C |
2: 88,854,170 (GRCm39) |
Y59C |
probably damaging |
Het |
| Or4f14 |
A |
T |
2: 111,742,905 (GRCm39) |
Y123* |
probably null |
Het |
| Or4n4b |
A |
T |
14: 50,536,139 (GRCm39) |
V209E |
probably benign |
Het |
| Or52ab7 |
T |
A |
7: 102,977,858 (GRCm39) |
I55N |
probably damaging |
Het |
| Or5b98 |
A |
G |
19: 12,931,066 (GRCm39) |
T38A |
possibly damaging |
Het |
| Or5h25 |
T |
A |
16: 58,930,588 (GRCm39) |
K128N |
probably benign |
Het |
| Or8k23 |
T |
C |
2: 86,186,007 (GRCm39) |
T240A |
probably damaging |
Het |
| Padi4 |
GCTGCGTACCTCCAC |
GC |
4: 140,475,760 (GRCm39) |
|
probably benign |
Het |
| Patj |
T |
A |
4: 98,457,347 (GRCm39) |
M1283K |
probably damaging |
Het |
| Pkd1 |
C |
T |
17: 24,804,657 (GRCm39) |
T790I |
probably damaging |
Het |
| Plod3 |
C |
A |
5: 137,020,465 (GRCm39) |
T526K |
probably benign |
Het |
| Plxnb2 |
C |
A |
15: 89,042,816 (GRCm39) |
|
probably benign |
Het |
| Polr1g |
G |
T |
7: 19,093,066 (GRCm39) |
P38Q |
probably damaging |
Het |
| Pramel1 |
T |
A |
4: 143,124,175 (GRCm39) |
D283E |
possibly damaging |
Het |
| Prpf40a |
T |
C |
2: 53,031,663 (GRCm39) |
|
probably benign |
Het |
| Psg23 |
A |
T |
7: 18,348,607 (GRCm39) |
Y67N |
probably damaging |
Het |
| Rftn1 |
T |
A |
17: 50,301,289 (GRCm39) |
Q242L |
possibly damaging |
Het |
| Rp1l1 |
A |
T |
14: 64,269,515 (GRCm39) |
E1700D |
probably benign |
Het |
| Scube3 |
T |
C |
17: 28,383,127 (GRCm39) |
F435S |
probably damaging |
Het |
| Sdk2 |
T |
C |
11: 113,671,836 (GRCm39) |
Y2104C |
probably damaging |
Het |
| Septin11 |
A |
G |
5: 93,313,227 (GRCm39) |
E358G |
possibly damaging |
Het |
| Sh3bp1 |
T |
C |
15: 78,789,975 (GRCm39) |
L246P |
probably damaging |
Het |
| Sis |
T |
C |
3: 72,858,975 (GRCm39) |
Y352C |
probably damaging |
Het |
| Skint1 |
T |
C |
4: 111,878,562 (GRCm39) |
S165P |
probably damaging |
Het |
| Skint10 |
C |
T |
4: 112,586,008 (GRCm39) |
|
probably benign |
Het |
| Slc1a2 |
A |
T |
2: 102,586,417 (GRCm39) |
R340S |
probably damaging |
Het |
| Slc26a3 |
C |
A |
12: 31,497,739 (GRCm39) |
Q48K |
probably benign |
Het |
| Slc5a2 |
A |
T |
7: 127,869,171 (GRCm39) |
Y317F |
probably damaging |
Het |
| Sorbs3 |
T |
A |
14: 70,431,375 (GRCm39) |
T262S |
probably benign |
Het |
| Tas2r118 |
G |
T |
6: 23,969,400 (GRCm39) |
S220R |
probably damaging |
Het |
| Terf2ip |
C |
A |
8: 112,741,974 (GRCm39) |
Q223K |
possibly damaging |
Het |
| Tespa1 |
A |
G |
10: 130,196,680 (GRCm39) |
Q206R |
probably damaging |
Het |
| Tex10 |
T |
C |
4: 48,462,766 (GRCm39) |
|
probably null |
Het |
| Tle1 |
T |
A |
4: 72,043,227 (GRCm39) |
K547N |
probably damaging |
Het |
| Tmem131l |
T |
A |
3: 83,805,853 (GRCm39) |
Q1530L |
probably damaging |
Het |
| Tomm20l |
A |
G |
12: 71,169,851 (GRCm39) |
E145G |
possibly damaging |
Het |
| Tra2a |
C |
T |
6: 49,227,885 (GRCm39) |
|
probably benign |
Het |
| Trim32 |
G |
A |
4: 65,531,491 (GRCm39) |
R16Q |
probably damaging |
Het |
| Trim37 |
T |
A |
11: 87,036,328 (GRCm39) |
Y121* |
probably null |
Het |
| Tube1 |
C |
T |
10: 39,016,941 (GRCm39) |
|
probably null |
Het |
| Usp6nl |
T |
A |
2: 6,425,820 (GRCm39) |
V187D |
probably damaging |
Het |
| Vmn1r13 |
T |
C |
6: 57,187,248 (GRCm39) |
F136L |
probably benign |
Het |
| Vmn1r201 |
A |
T |
13: 22,659,316 (GRCm39) |
I177F |
probably benign |
Het |
| Vmn1r203 |
A |
T |
13: 22,708,443 (GRCm39) |
T75S |
possibly damaging |
Het |
| Vmn1r225 |
C |
T |
17: 20,722,718 (GRCm39) |
S53L |
probably benign |
Het |
| Xab2 |
A |
T |
8: 3,660,994 (GRCm39) |
W707R |
probably damaging |
Het |
| Zfp808 |
T |
C |
13: 62,317,248 (GRCm39) |
|
probably benign |
Het |
| Zng1 |
A |
G |
19: 24,926,575 (GRCm39) |
Y159H |
possibly damaging |
Het |
|
| Other mutations in Myom2 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00422:Myom2
|
APN |
8 |
15,119,490 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL00426:Myom2
|
APN |
8 |
15,119,502 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL00503:Myom2
|
APN |
8 |
15,164,289 (GRCm39) |
splice site |
probably null |
|
|
IGL01515:Myom2
|
APN |
8 |
15,172,655 (GRCm39) |
missense |
probably benign |
0.15 |
|
IGL01649:Myom2
|
APN |
8 |
15,163,755 (GRCm39) |
missense |
probably benign |
0.24 |
|
IGL01658:Myom2
|
APN |
8 |
15,127,880 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01786:Myom2
|
APN |
8 |
15,156,330 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL01924:Myom2
|
APN |
8 |
15,119,685 (GRCm39) |
missense |
probably benign |
0.37 |
|
IGL01929:Myom2
|
APN |
8 |
15,167,698 (GRCm39) |
missense |
probably damaging |
0.96 |
|
IGL02016:Myom2
|
APN |
8 |
15,175,195 (GRCm39) |
missense |
probably benign |
0.01 |
|
IGL02511:Myom2
|
APN |
8 |
15,115,743 (GRCm39) |
missense |
probably benign |
|
|
IGL02558:Myom2
|
APN |
8 |
15,164,237 (GRCm39) |
missense |
probably benign |
0.31 |
|
IGL02944:Myom2
|
APN |
8 |
15,154,065 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
IGL03052:Myom2
|
APN |
8 |
15,173,442 (GRCm39) |
splice site |
probably benign |
|
|
IGL03195:Myom2
|
APN |
8 |
15,161,844 (GRCm39) |
nonsense |
probably null |
|
|
IGL03288:Myom2
|
APN |
8 |
15,172,679 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL03402:Myom2
|
APN |
8 |
15,115,731 (GRCm39) |
missense |
probably benign |
|
|
yomama
|
UTSW |
8 |
15,182,895 (GRCm39) |
missense |
probably benign |
0.10 |
|
yoyoma
|
UTSW |
8 |
15,182,667 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R0069:Myom2
|
UTSW |
8 |
15,167,624 (GRCm39) |
missense |
probably benign |
|
|
R0116:Myom2
|
UTSW |
8 |
15,167,633 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0131:Myom2
|
UTSW |
8 |
15,133,329 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R0373:Myom2
|
UTSW |
8 |
15,148,419 (GRCm39) |
missense |
possibly damaging |
0.91 |
|
R0463:Myom2
|
UTSW |
8 |
15,154,123 (GRCm39) |
missense |
probably benign |
0.09 |
|
R0629:Myom2
|
UTSW |
8 |
15,119,783 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R0634:Myom2
|
UTSW |
8 |
15,169,216 (GRCm39) |
splice site |
probably benign |
|
|
R0645:Myom2
|
UTSW |
8 |
15,167,698 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R0730:Myom2
|
UTSW |
8 |
15,149,326 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0744:Myom2
|
UTSW |
8 |
15,182,924 (GRCm39) |
nonsense |
probably null |
|
|
R0836:Myom2
|
UTSW |
8 |
15,182,924 (GRCm39) |
nonsense |
probably null |
|
|
R1033:Myom2
|
UTSW |
8 |
15,158,934 (GRCm39) |
missense |
probably benign |
0.04 |
|
R1103:Myom2
|
UTSW |
8 |
15,160,827 (GRCm39) |
missense |
probably benign |
0.22 |
|
R1110:Myom2
|
UTSW |
8 |
15,172,413 (GRCm39) |
missense |
probably benign |
0.44 |
|
R1208:Myom2
|
UTSW |
8 |
15,134,631 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1208:Myom2
|
UTSW |
8 |
15,134,631 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1353:Myom2
|
UTSW |
8 |
15,156,424 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1530:Myom2
|
UTSW |
8 |
15,172,384 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1544:Myom2
|
UTSW |
8 |
15,154,059 (GRCm39) |
splice site |
probably benign |
|
|
R1576:Myom2
|
UTSW |
8 |
15,134,556 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1758:Myom2
|
UTSW |
8 |
15,115,795 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1884:Myom2
|
UTSW |
8 |
15,164,278 (GRCm39) |
missense |
probably benign |
0.01 |
|
R1908:Myom2
|
UTSW |
8 |
15,131,023 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1962:Myom2
|
UTSW |
8 |
15,182,599 (GRCm39) |
splice site |
probably null |
|
|
R1977:Myom2
|
UTSW |
8 |
15,135,263 (GRCm39) |
missense |
possibly damaging |
0.47 |
|
R2018:Myom2
|
UTSW |
8 |
15,181,151 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2049:Myom2
|
UTSW |
8 |
15,156,379 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R2155:Myom2
|
UTSW |
8 |
15,134,555 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R2314:Myom2
|
UTSW |
8 |
15,113,927 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R2350:Myom2
|
UTSW |
8 |
15,158,835 (GRCm39) |
missense |
probably benign |
0.09 |
|
R2358:Myom2
|
UTSW |
8 |
15,162,018 (GRCm39) |
missense |
possibly damaging |
0.68 |
|
R2904:Myom2
|
UTSW |
8 |
15,148,348 (GRCm39) |
missense |
probably benign |
0.00 |
|
R3418:Myom2
|
UTSW |
8 |
15,135,294 (GRCm39) |
missense |
probably benign |
0.01 |
|
R3606:Myom2
|
UTSW |
8 |
15,119,775 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3607:Myom2
|
UTSW |
8 |
15,119,775 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3735:Myom2
|
UTSW |
8 |
15,119,676 (GRCm39) |
missense |
probably benign |
0.01 |
|
R3756:Myom2
|
UTSW |
8 |
15,152,650 (GRCm39) |
missense |
probably benign |
0.11 |
|
R3902:Myom2
|
UTSW |
8 |
15,154,165 (GRCm39) |
missense |
probably benign |
|
|
R3951:Myom2
|
UTSW |
8 |
15,134,556 (GRCm39) |
missense |
probably benign |
0.35 |
|
R4240:Myom2
|
UTSW |
8 |
15,182,895 (GRCm39) |
missense |
probably benign |
0.10 |
|
R4361:Myom2
|
UTSW |
8 |
15,162,018 (GRCm39) |
missense |
possibly damaging |
0.68 |
|
R4581:Myom2
|
UTSW |
8 |
15,156,459 (GRCm39) |
missense |
probably benign |
0.02 |
|
R4736:Myom2
|
UTSW |
8 |
15,131,271 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5010:Myom2
|
UTSW |
8 |
15,133,310 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R5108:Myom2
|
UTSW |
8 |
15,182,667 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5370:Myom2
|
UTSW |
8 |
15,149,343 (GRCm39) |
missense |
probably benign |
0.10 |
|
R5427:Myom2
|
UTSW |
8 |
15,163,764 (GRCm39) |
missense |
probably benign |
0.03 |
|
R5498:Myom2
|
UTSW |
8 |
15,179,142 (GRCm39) |
missense |
probably benign |
0.01 |
|
R5504:Myom2
|
UTSW |
8 |
15,178,879 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5567:Myom2
|
UTSW |
8 |
15,152,546 (GRCm39) |
missense |
probably benign |
0.01 |
|
R5743:Myom2
|
UTSW |
8 |
15,130,914 (GRCm39) |
missense |
possibly damaging |
0.82 |
|
R5745:Myom2
|
UTSW |
8 |
15,172,705 (GRCm39) |
missense |
probably benign |
0.01 |
|
R5844:Myom2
|
UTSW |
8 |
15,181,182 (GRCm39) |
critical splice donor site |
probably null |
|
|
R5854:Myom2
|
UTSW |
8 |
15,158,478 (GRCm39) |
missense |
probably benign |
|
|
R6141:Myom2
|
UTSW |
8 |
15,113,903 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6209:Myom2
|
UTSW |
8 |
15,154,173 (GRCm39) |
missense |
possibly damaging |
0.76 |
|
R6248:Myom2
|
UTSW |
8 |
15,148,472 (GRCm39) |
splice site |
probably null |
|
|
R6378:Myom2
|
UTSW |
8 |
15,149,356 (GRCm39) |
missense |
probably benign |
0.11 |
|
R6829:Myom2
|
UTSW |
8 |
15,172,643 (GRCm39) |
nonsense |
probably null |
|
|
R6913:Myom2
|
UTSW |
8 |
15,115,710 (GRCm39) |
missense |
probably benign |
|
|
R6957:Myom2
|
UTSW |
8 |
15,167,741 (GRCm39) |
missense |
probably null |
0.42 |
|
R6958:Myom2
|
UTSW |
8 |
15,167,741 (GRCm39) |
missense |
probably null |
0.42 |
|
R6960:Myom2
|
UTSW |
8 |
15,167,741 (GRCm39) |
missense |
probably null |
0.42 |
|
R6961:Myom2
|
UTSW |
8 |
15,167,741 (GRCm39) |
missense |
probably null |
0.42 |
|
R6962:Myom2
|
UTSW |
8 |
15,167,741 (GRCm39) |
missense |
probably null |
0.42 |
|
R6999:Myom2
|
UTSW |
8 |
15,134,531 (GRCm39) |
missense |
probably benign |
0.22 |
|
R7148:Myom2
|
UTSW |
8 |
15,134,577 (GRCm39) |
missense |
possibly damaging |
0.72 |
|
R7210:Myom2
|
UTSW |
8 |
15,154,114 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7298:Myom2
|
UTSW |
8 |
15,148,411 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7463:Myom2
|
UTSW |
8 |
15,167,679 (GRCm39) |
missense |
probably null |
0.94 |
|
R7535:Myom2
|
UTSW |
8 |
15,167,679 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7573:Myom2
|
UTSW |
8 |
15,172,450 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7590:Myom2
|
UTSW |
8 |
15,167,679 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7690:Myom2
|
UTSW |
8 |
15,161,717 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
R7794:Myom2
|
UTSW |
8 |
15,133,259 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7822:Myom2
|
UTSW |
8 |
15,158,454 (GRCm39) |
missense |
probably benign |
|
|
R7948:Myom2
|
UTSW |
8 |
15,135,306 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8094:Myom2
|
UTSW |
8 |
15,119,418 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R8268:Myom2
|
UTSW |
8 |
15,179,157 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8292:Myom2
|
UTSW |
8 |
15,182,888 (GRCm39) |
missense |
probably benign |
0.01 |
|
R8514:Myom2
|
UTSW |
8 |
15,175,153 (GRCm39) |
missense |
possibly damaging |
0.65 |
|
R8539:Myom2
|
UTSW |
8 |
15,164,254 (GRCm39) |
missense |
probably benign |
0.01 |
|
R8790:Myom2
|
UTSW |
8 |
15,169,242 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8824:Myom2
|
UTSW |
8 |
15,164,169 (GRCm39) |
missense |
possibly damaging |
0.82 |
|
R8895:Myom2
|
UTSW |
8 |
15,152,589 (GRCm39) |
nonsense |
probably null |
|
|
R9024:Myom2
|
UTSW |
8 |
15,113,936 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9129:Myom2
|
UTSW |
8 |
15,154,068 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9224:Myom2
|
UTSW |
8 |
15,178,804 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R9237:Myom2
|
UTSW |
8 |
15,152,591 (GRCm39) |
missense |
possibly damaging |
0.85 |
|
R9321:Myom2
|
UTSW |
8 |
15,172,464 (GRCm39) |
missense |
possibly damaging |
0.91 |
|
R9341:Myom2
|
UTSW |
8 |
15,134,633 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R9343:Myom2
|
UTSW |
8 |
15,134,633 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R9375:Myom2
|
UTSW |
8 |
15,149,210 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9455:Myom2
|
UTSW |
8 |
15,156,293 (GRCm39) |
missense |
probably benign |
0.31 |
|
R9563:Myom2
|
UTSW |
8 |
15,158,399 (GRCm39) |
nonsense |
probably null |
|
|
R9565:Myom2
|
UTSW |
8 |
15,158,399 (GRCm39) |
nonsense |
probably null |
|
|
RF001:Myom2
|
UTSW |
8 |
15,131,418 (GRCm39) |
missense |
possibly damaging |
0.64 |
|
| Predicted Primers |
PCR Primer
(F):5'- GCACGCAAATGGTCTAATGCTTCAC -3'
(R):5'- TTCTGAAAGAGCCGCCCATGTC -3'
Sequencing Primer
(F):5'- ATGCTTCACTAACCGTGGGC -3'
(R):5'- GTCCCTAAAATTTGAATGGCAGAGC -3'
|
| Posted On |
2013-06-11 |
Incidental Mutation