Mutagenetix > Incidental Mutations

Incidental Mutation 'R5791:Tex26'

446968

Institutional Source

Beutler Lab

Gene Symbol

Tex26

Ensembl Gene

ENSMUSG00000029660

Gene Name

testis expressed 26

Synonyms

MMRRC Submission

043207-MU

Accession Numbers

Is this an essential gene?

Probably non essential (E-score: 0.063) question?

Stock #

R5791 (G1)

Quality Score

225

Status

Not validated

Chromosome

Chromosomal Location

149439660-149470979 bp(+) (GRCm38)

Type of Mutation

utr 5 prime

DNA Base Change (assembly)

A to T at 149439775 bp

Zygosity

Heterozygous

Amino Acid Change

Ref Sequence

ENSEMBL: ENSMUSP00000143863 (fasta)

Predicted Effect

probably null
Transcript: ENSMUST00000031667
AA Change: K17*

Predicted Effect

probably benign
Transcript: ENSMUST00000200985

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000201035

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000201454

Predicted Effect

probably null
Transcript: ENSMUST00000201610
AA Change: K17*

Predicted Effect

probably null
Transcript: ENSMUST00000201683
AA Change: K17*

Predicted Effect

probably null
Transcript: ENSMUST00000202677
AA Change: K17*

Predicted Effect

probably null
Transcript: ENSMUST00000202920

Coding Region Coverage

1x: 99.3%
3x: 98.8%
10x: 97.6%
20x: 96.1%

Validation Efficiency

Allele List at MGI

Other mutations in this stock

Total: 39 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
Adam25	G	C	8: 40,754,220	Q174H	probably benign	Het
Adipor2	A	T	6: 119,361,905	M129K	possibly damaging	Het
AI314180	C	T	4: 58,814,027	E1360K	possibly damaging	Het
AI314180	T	A	4: 58,822,111	D1152V	probably damaging	Het
Arhgap29	T	A	3: 122,014,245	M616K	probably damaging	Het
Calcrl	A	T	2: 84,351,265	F180I	probably damaging	Het
Cdh4	T	C	2: 179,895,767	V864A	probably damaging	Het
Cep78	A	G	19: 15,961,072	F504S	probably benign	Het
Coasy	A	G	11: 101,084,385		probably null	Het
Dnah3	T	C	7: 119,931,473	N751S	probably benign	Het
Eea1	T	A	10: 96,019,995	N631K	probably benign	Het
Fam149b	A	G	14: 20,351,326	K27R	probably damaging	Het
Fbxw26	A	G	9: 109,745,153	W42R	probably damaging	Het
Gas6	A	G	8: 13,470,217		probably null	Het
Gfral	C	T	9: 76,197,046	R228Q	probably benign	Het
Gm11595	G	A	11: 99,772,555	R100C	unknown	Het
Gmppa	T	C	1: 75,442,255	V324A	possibly damaging	Het
Gstm2	C	T	3: 107,984,128		probably null	Het
Kcng3	A	G	17: 83,588,210	S276P	probably benign	Het
Lrrd1	T	C	5: 3,851,254	S520P	probably benign	Het
Lrrn2	A	G	1: 132,937,767	N190S	probably benign	Het
Lrwd1	G	C	5: 136,131,033	A392G	probably benign	Het
Mab21l2	A	G	3: 86,546,737	Y319H	probably damaging	Het
Ndufv3	A	G	17: 31,527,408	N91D	probably benign	Het
Nfatc2	T	A	2: 168,536,393	M451L	probably benign	Het
Olfr980	A	T	9: 40,006,734	S72T	probably damaging	Het
Pcdhgb2	G	T	18: 37,692,340	V795F	possibly damaging	Het
Pdcd11	T	A	19: 47,110,991	M843K	possibly damaging	Het
Pla2g4c	T	A	7: 13,339,692	N221K	probably benign	Het
Ppox	T	C	1: 171,277,312	Y422C	probably damaging	Het
Retreg3	A	G	11: 101,100,943	S55P	probably damaging	Het
Rnf103	C	A	6: 71,508,925	T180K	probably damaging	Het
Tbl3	A	T	17: 24,704,434	L307H	probably damaging	Het
Tln2	A	T	9: 67,386,605	I247K	probably damaging	Het
Txlnb	T	C	10: 17,799,128	S10P	probably benign	Het
Vwde	C	A	6: 13,195,986	E347*	probably null	Het
Wasf1	G	A	10: 40,926,574	R75Q	probably damaging	Het
Zfp14	A	G	7: 30,038,262	S433P	probably damaging	Het
Zfp647	G	T	15: 76,918,006	A2E	unknown	Het

Other mutations in Tex26

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL02527:Tex26	APN	5	149456942	missense	probably damaging	1.00
R0401:Tex26	UTSW	5	149460858	missense	probably benign	0.01
R2063:Tex26	UTSW	5	149439739	missense	probably damaging	0.98
R2424:Tex26	UTSW	5	149470448	utr 3 prime	probably benign
R3779:Tex26	UTSW	5	149445851	missense	probably damaging	0.96
R4361:Tex26	UTSW	5	149460923	missense	probably benign	0.01
R4434:Tex26	UTSW	5	149453355	missense	probably benign	0.08
R5804:Tex26	UTSW	5	149463147	missense	possibly damaging	0.92

Predicted Primers

PCR Primer
(F):5'- GGGCACTCCATGAAAGTCAG -3'
(R):5'- GGACAGCTGATCTTTCTCCCTG -3'

Sequencing Primer
(F):5'- TCAGGAATCAGCGTGATGC -3'
(R):5'- CCCTGACTCACTTGCGC -3'

Posted On

2016-12-15