|Institutional Source||Beutler Lab|
|Gene Name||RIKEN cDNA 4932438A13 gene|
|Essential gene?||Essential (E-score: 1.000)|
|Stock #||R0545 (G1)|
|Chromosomal Location||36863104-37053033 bp(+) (GRCm38)|
|Type of Mutation||splice site|
|DNA Base Change (assembly)||G to A at 36987690 bp (GRCm38)|
|Amino Acid Change|
|Ref Sequence||ENSEMBL: ENSMUSP00000148720 (fasta)|
|Gene Model||predicted gene model for transcript(s): [ENSMUST00000057272] [ENSMUST00000152564] [ENSMUST00000211820]|
|AlphaFold||no structure available at present|
|Coding Region Coverage||
|Validation Efficiency||99% (66/67)|
|MGI Phenotype||FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene is located on the long arm of chromosome 4 in a region that is associated with susceptibility to celiac disease. The encoded protein is similar to a Chinese hamster protein that is associated with spermatocyte and adipocyte differentiation. The C-terminus of the protein is also similar to a Caenorhabditis elegans protein that plays a role in lipid storage. In mammals, this protein is thought to function in the regulation of epithelial growth and differentiation, and in tumor development. [provided by RefSeq, Oct 2009]|
|Allele List at MGI|
|Other mutations in this stock||
|Other mutations in 4932438A13Rik||
(F):5'- AGTTCGAGAGGGAGTCTCAATGGTG -3'
(R):5'- AGCAGTCTATGTCAGGGTCAAGGAG -3'
(F):5'- AGTCTCAATGGTGGCAACAG -3'
(R):5'- TCAGGGTCAAGGAGGAAGTATG -3'