Mutagenetix > Incidental Mutations

Incidental Mutation 'R5821:Clasp1'

449911

Institutional Source

Beutler Lab

Gene Symbol

Clasp1

Ensembl Gene

ENSMUSG00000064302

Gene Name

CLIP associating protein 1

Synonyms

1700030C23Rik, B130045P17Rik, CLASP1, mCLASP1, 5730583A19Rik, CLASP1alpha

MMRRC Submission

043401-MU

Accession Numbers

Is this an essential gene?

Probably essential (E-score: 0.950) question?

Stock #

R5821 (G1)

Quality Score

225

Status

Validated

Chromosome

Chromosomal Location

118389058-118612678 bp(+) (GRCm38)

Type of Mutation

missense

DNA Base Change (assembly)

T to A at 118590484 bp

Zygosity

Heterozygous

Amino Acid Change

Phenylalanine to Isoleucine at position 1087 (F1087I)

Ref Sequence

ENSEMBL: ENSMUSP00000142203 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000049404] [ENSMUST00000070989] [ENSMUST00000165223] [ENSMUST00000178710] [ENSMUST00000185405] [ENSMUST00000186349] [ENSMUST00000187713] [ENSMUST00000188710] [ENSMUST00000189262] [ENSMUST00000189570] [ENSMUST00000189738] [ENSMUST00000190571] [ENSMUST00000190733] [ENSMUST00000191823] [ENSMUST00000191445] [ENSMUST00000204325]

Predicted Effect

probably damaging
Transcript: ENSMUST00000049404
AA Change: F1379I

PolyPhen 2 Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)

SMART Domains

Protein: ENSMUSP00000042266
Gene: ENSMUSG00000064302
AA Change: F1379I

Domain	Start	End	E-Value	Type
TOG	1	232	7.31e-51	SMART
low complexity region	252	266	N/A	INTRINSIC
low complexity region	280	296	N/A	INTRINSIC
TOG	319	551	1.14e-11	SMART
low complexity region	579	594	N/A	INTRINSIC
low complexity region	606	633	N/A	INTRINSIC
low complexity region	674	707	N/A	INTRINSIC
low complexity region	751	763	N/A	INTRINSIC
low complexity region	821	831	N/A	INTRINSIC
TOG	847	1085	3.23e-1	SMART
low complexity region	1096	1113	N/A	INTRINSIC
low complexity region	1134	1147	N/A	INTRINSIC
low complexity region	1225	1236	N/A	INTRINSIC
TOG	1287	1525	4.96e-30	SMART

Predicted Effect

probably damaging
Transcript: ENSMUST00000070989
AA Change: F1369I

PolyPhen 2 Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)

SMART Domains

Protein: ENSMUSP00000067858
Gene: ENSMUSG00000064302
AA Change: F1369I

Domain	Start	End	E-Value	Type
TOG	1	232	7.31e-51	SMART
low complexity region	252	266	N/A	INTRINSIC
low complexity region	280	296	N/A	INTRINSIC
TOG	319	551	1.14e-11	SMART
low complexity region	579	594	N/A	INTRINSIC
low complexity region	606	633	N/A	INTRINSIC
low complexity region	674	707	N/A	INTRINSIC
low complexity region	751	763	N/A	INTRINSIC
low complexity region	850	860	N/A	INTRINSIC
TOG	876	1114	3.23e-1	SMART
low complexity region	1125	1142	N/A	INTRINSIC
low complexity region	1215	1226	N/A	INTRINSIC
TOG	1277	1515	4.96e-30	SMART

Predicted Effect

probably damaging
Transcript: ENSMUST00000165223
AA Change: F1295I

PolyPhen 2 Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)

SMART Domains

Protein: ENSMUSP00000128089
Gene: ENSMUSG00000064302
AA Change: F1295I

Domain	Start	End	E-Value	Type
TOG	1	232	7.31e-51	SMART
low complexity region	252	266	N/A	INTRINSIC
low complexity region	280	296	N/A	INTRINSIC
TOG	319	551	1.14e-11	SMART
low complexity region	579	594	N/A	INTRINSIC
low complexity region	606	633	N/A	INTRINSIC
low complexity region	684	714	N/A	INTRINSIC
low complexity region	792	802	N/A	INTRINSIC
TOG	818	1056	3.23e-1	SMART
low complexity region	1067	1084	N/A	INTRINSIC
low complexity region	1157	1168	N/A	INTRINSIC
TOG	1219	1457	4.96e-30	SMART

Predicted Effect

probably damaging
Transcript: ENSMUST00000178710
AA Change: F1302I

PolyPhen 2 Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)

SMART Domains

Protein: ENSMUSP00000137137
Gene: ENSMUSG00000064302
AA Change: F1302I

Domain	Start	End	E-Value	Type
TOG	1	232	7.31e-51	SMART
low complexity region	252	266	N/A	INTRINSIC
low complexity region	280	296	N/A	INTRINSIC
TOG	319	551	1.14e-11	SMART
low complexity region	579	594	N/A	INTRINSIC
low complexity region	606	633	N/A	INTRINSIC
low complexity region	668	698	N/A	INTRINSIC
low complexity region	752	766	N/A	INTRINSIC
low complexity region	784	794	N/A	INTRINSIC
TOG	810	1047	6.55e-2	SMART
low complexity region	1058	1075	N/A	INTRINSIC
low complexity region	1148	1159	N/A	INTRINSIC
TOG	1210	1448	4.96e-30	SMART

Predicted Effect

probably damaging
Transcript: ENSMUST00000185405
AA Change: F1335I

PolyPhen 2 Score 0.999 (Sensitivity: 0.14; Specificity: 0.99)

SMART Domains

Protein: ENSMUSP00000139619
Gene: ENSMUSG00000064302
AA Change: F1335I

Domain	Start	End	E-Value	Type
TOG	1	232	3.4e-55	SMART
low complexity region	252	266	N/A	INTRINSIC
low complexity region	280	296	N/A	INTRINSIC
TOG	319	551	5.5e-16	SMART
low complexity region	579	594	N/A	INTRINSIC
low complexity region	606	633	N/A	INTRINSIC
low complexity region	682	715	N/A	INTRINSIC
low complexity region	769	783	N/A	INTRINSIC
low complexity region	801	811	N/A	INTRINSIC
TOG	827	1065	1.6e-5	SMART
low complexity region	1076	1093	N/A	INTRINSIC
low complexity region	1166	1177	N/A	INTRINSIC
TOG	1228	1466	2.3e-34	SMART

Predicted Effect

probably damaging
Transcript: ENSMUST00000186349
AA Change: F1379I

PolyPhen 2 Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)

SMART Domains

Protein: ENSMUSP00000141105
Gene: ENSMUSG00000064302
AA Change: F1379I

Domain	Start	End	E-Value	Type
TOG	1	232	7.31e-51	SMART
low complexity region	252	266	N/A	INTRINSIC
low complexity region	280	296	N/A	INTRINSIC
TOG	319	551	1.14e-11	SMART
low complexity region	579	594	N/A	INTRINSIC
low complexity region	606	633	N/A	INTRINSIC
low complexity region	674	707	N/A	INTRINSIC
low complexity region	751	763	N/A	INTRINSIC
low complexity region	821	831	N/A	INTRINSIC
TOG	847	1085	3.23e-1	SMART
low complexity region	1096	1113	N/A	INTRINSIC
low complexity region	1134	1147	N/A	INTRINSIC
low complexity region	1225	1236	N/A	INTRINSIC
TOG	1287	1525	4.96e-30	SMART

Predicted Effect

probably damaging
Transcript: ENSMUST00000187713
AA Change: F1318I

PolyPhen 2 Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)

SMART Domains

Protein: ENSMUSP00000139526
Gene: ENSMUSG00000064302
AA Change: F1318I

Domain	Start	End	E-Value	Type
TOG	1	232	3.4e-55	SMART
low complexity region	252	266	N/A	INTRINSIC
low complexity region	280	296	N/A	INTRINSIC
TOG	319	551	5.5e-16	SMART
low complexity region	579	594	N/A	INTRINSIC
low complexity region	606	633	N/A	INTRINSIC
low complexity region	684	714	N/A	INTRINSIC
low complexity region	768	782	N/A	INTRINSIC
low complexity region	800	810	N/A	INTRINSIC
TOG	826	1064	1.6e-5	SMART
low complexity region	1075	1092	N/A	INTRINSIC
low complexity region	1165	1176	N/A	INTRINSIC
TOG	1227	1465	2.3e-34	SMART

Predicted Effect

probably damaging
Transcript: ENSMUST00000188710
AA Change: F1369I

PolyPhen 2 Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)

SMART Domains

Protein: ENSMUSP00000140593
Gene: ENSMUSG00000064302
AA Change: F1369I

Domain	Start	End	E-Value	Type
TOG	1	232	3.4e-55	SMART
low complexity region	252	266	N/A	INTRINSIC
low complexity region	280	296	N/A	INTRINSIC
TOG	319	551	5.5e-16	SMART
low complexity region	579	594	N/A	INTRINSIC
low complexity region	606	633	N/A	INTRINSIC
low complexity region	674	707	N/A	INTRINSIC
low complexity region	751	763	N/A	INTRINSIC
low complexity region	818	832	N/A	INTRINSIC
low complexity region	850	860	N/A	INTRINSIC
TOG	876	1114	1.6e-5	SMART
low complexity region	1125	1142	N/A	INTRINSIC
low complexity region	1215	1226	N/A	INTRINSIC
TOG	1277	1515	2.3e-34	SMART

Predicted Effect

probably damaging
Transcript: ENSMUST00000189262
AA Change: F1303I

PolyPhen 2 Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)

SMART Domains

Protein: ENSMUSP00000140860
Gene: ENSMUSG00000064302
AA Change: F1303I

Domain	Start	End	E-Value	Type
TOG	1	232	3.4e-55	SMART
low complexity region	252	266	N/A	INTRINSIC
low complexity region	280	296	N/A	INTRINSIC
TOG	319	551	5.5e-16	SMART
low complexity region	579	594	N/A	INTRINSIC
low complexity region	606	633	N/A	INTRINSIC
low complexity region	668	698	N/A	INTRINSIC
low complexity region	776	786	N/A	INTRINSIC
TOG	802	1040	1.6e-5	SMART
low complexity region	1051	1068	N/A	INTRINSIC
low complexity region	1141	1152	N/A	INTRINSIC
TOG	1203	1441	2.3e-34	SMART

Predicted Effect

probably damaging
Transcript: ENSMUST00000189570
AA Change: F1311I

PolyPhen 2 Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)

SMART Domains

Protein: ENSMUSP00000140167
Gene: ENSMUSG00000064302
AA Change: F1311I

Domain	Start	End	E-Value	Type
TOG	1	232	3.4e-55	SMART
low complexity region	252	266	N/A	INTRINSIC
low complexity region	280	296	N/A	INTRINSIC
TOG	319	551	5.5e-16	SMART
low complexity region	579	594	N/A	INTRINSIC
low complexity region	606	633	N/A	INTRINSIC
low complexity region	684	714	N/A	INTRINSIC
low complexity region	792	802	N/A	INTRINSIC
TOG	818	1055	3.2e-6	SMART
low complexity region	1066	1083	N/A	INTRINSIC
low complexity region	1156	1167	N/A	INTRINSIC
TOG	1218	1456	2.3e-34	SMART

Predicted Effect

probably damaging
Transcript: ENSMUST00000189738
AA Change: F1320I

PolyPhen 2 Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)

SMART Domains

Protein: ENSMUSP00000140665
Gene: ENSMUSG00000064302
AA Change: F1320I

Domain	Start	End	E-Value	Type
TOG	1	232	7.31e-51	SMART
low complexity region	252	266	N/A	INTRINSIC
low complexity region	280	296	N/A	INTRINSIC
TOG	319	551	1.14e-11	SMART
low complexity region	579	594	N/A	INTRINSIC
low complexity region	606	633	N/A	INTRINSIC
low complexity region	668	698	N/A	INTRINSIC
low complexity region	752	766	N/A	INTRINSIC
low complexity region	784	794	N/A	INTRINSIC
TOG	810	1048	3.23e-1	SMART
low complexity region	1059	1076	N/A	INTRINSIC
low complexity region	1149	1160	N/A	INTRINSIC
TOG	1211	1449	4.96e-30	SMART

Predicted Effect

probably damaging
Transcript: ENSMUST00000190571
AA Change: F1395I

PolyPhen 2 Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)

SMART Domains

Protein: ENSMUSP00000140019
Gene: ENSMUSG00000064302
AA Change: F1395I

Domain	Start	End	E-Value	Type
TOG	1	232	3.4e-55	SMART
low complexity region	252	266	N/A	INTRINSIC
low complexity region	280	296	N/A	INTRINSIC
TOG	319	551	5.5e-16	SMART
low complexity region	579	594	N/A	INTRINSIC
low complexity region	606	633	N/A	INTRINSIC
low complexity region	682	715	N/A	INTRINSIC
low complexity region	759	771	N/A	INTRINSIC
low complexity region	805	819	N/A	INTRINSIC
low complexity region	837	847	N/A	INTRINSIC
TOG	863	1101	1.6e-5	SMART
low complexity region	1112	1129	N/A	INTRINSIC
low complexity region	1150	1163	N/A	INTRINSIC
low complexity region	1241	1252	N/A	INTRINSIC
TOG	1303	1541	2.3e-34	SMART

Predicted Effect

probably benign
Transcript: ENSMUST00000190733

Predicted Effect

probably damaging
Transcript: ENSMUST00000191823
AA Change: F1087I

PolyPhen 2 Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)

SMART Domains

Protein: ENSMUSP00000142203
Gene: ENSMUSG00000064302
AA Change: F1087I

Domain	Start	End	E-Value	Type
low complexity region	20	34	N/A	INTRINSIC
low complexity region	48	64	N/A	INTRINSIC
TOG	87	319	5.6e-16	SMART
low complexity region	347	362	N/A	INTRINSIC
low complexity region	374	401	N/A	INTRINSIC
low complexity region	450	483	N/A	INTRINSIC
low complexity region	537	551	N/A	INTRINSIC
low complexity region	568	578	N/A	INTRINSIC
TOG	594	832	1.6e-5	SMART
low complexity region	843	860	N/A	INTRINSIC
low complexity region	933	944	N/A	INTRINSIC
TOG	995	1233	2.4e-34	SMART

Predicted Effect

probably damaging
Transcript: ENSMUST00000191445
AA Change: F1312I

PolyPhen 2 Score 0.965 (Sensitivity: 0.78; Specificity: 0.95)

SMART Domains

Protein: ENSMUSP00000140095
Gene: ENSMUSG00000064302
AA Change: F1312I

Domain	Start	End	E-Value	Type
TOG	1	232	3.4e-55	SMART
low complexity region	252	266	N/A	INTRINSIC
low complexity region	280	296	N/A	INTRINSIC
TOG	319	551	5.5e-16	SMART
low complexity region	579	594	N/A	INTRINSIC
low complexity region	606	633	N/A	INTRINSIC
low complexity region	674	707	N/A	INTRINSIC
low complexity region	761	775	N/A	INTRINSIC
low complexity region	793	803	N/A	INTRINSIC
TOG	819	1056	3.2e-6	SMART
low complexity region	1067	1084	N/A	INTRINSIC
low complexity region	1157	1168	N/A	INTRINSIC
TOG	1219	1457	2.3e-34	SMART

Predicted Effect

probably benign
Transcript: ENSMUST00000204325

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000203646

Meta Mutation Damage Score

0.2914

Coding Region Coverage

1x: 99.9%
3x: 99.7%
10x: 98.6%
20x: 96.1%

Validation Efficiency

100% (55/55)

MGI Phenotype

FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] CLASPs, such as CLASP1, are nonmotor microtubule-associated proteins that interact with CLIPs (e.g., CLIP170; MIM 179838). CLASP1 is involved in the regulation of microtubule dynamics at the kinetochore and throughout the spindle (Maiato et al., 2003 [PubMed 12837247]).[supplied by OMIM, Mar 2008]

Allele List at MGI

Other mutations in this stock

Total: 45 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
1700001O22Rik	A	T	2: 30,796,446	V278D	possibly damaging	Het
Acacb	A	G	5: 114,184,106	D227G	possibly damaging	Het
Akap9	A	G	5: 4,046,064	E2313G	probably benign	Het
Cchcr1	A	T	17: 35,528,848	E564D	probably damaging	Het
Cers2	G	A	3: 95,321,697		probably benign	Het
Cfap161	A	G	7: 83,775,980	I301T	probably benign	Het
Ciita	A	T	16: 10,511,805	E648V	possibly damaging	Het
Cir1	C	T	2: 73,312,460	C10Y	probably damaging	Het
Cped1	C	A	6: 22,138,682	F415L	probably benign	Het
Dnah7b	A	G	1: 46,142,132	T1060A	possibly damaging	Het
Epha5	G	T	5: 84,084,728	P809H	probably damaging	Het
Fuca1	T	A	4: 135,922,962		probably null	Het
Gm20388	A	T	8: 122,900,633	*98R	probably null	Het
Gm26796	G	A	12: 80,758,790	R237C	unknown	Het
Idua	A	G	5: 108,679,734	Y138C	probably benign	Het
Ighd	A	T	12: 113,409,633	L240H	probably benign	Het
Ing2	C	G	8: 47,668,826	C229S	probably benign	Het
Kat8	G	A	7: 127,924,816	E343K	probably damaging	Het
Kctd8	A	T	5: 69,110,485	N427K	probably benign	Het
Kif16b	T	C	2: 142,702,666	E1147G	probably damaging	Het
Kif18a	G	A	2: 109,289,845		probably benign	Het
Krt82	T	A	15: 101,548,385	R187*	probably null	Het
Lrrk2	T	C	15: 91,709,390		probably null	Het
M1ap	T	C	6: 82,968,102	Y126H	probably benign	Het
Mmel1	A	G	4: 154,885,587	N226D	possibly damaging	Het
Mtmr11	A	G	3: 96,167,869	D353G	possibly damaging	Het
Nfkbia	A	T	12: 55,491,220	H149Q	probably damaging	Het
Nr5a1	A	T	2: 38,708,499	F95L	probably damaging	Het
Nutm2	A	G	13: 50,469,855	Y196C	probably benign	Het
Oxtr	A	G	6: 112,489,496	I101T	probably damaging	Het
Pcsk2	T	A	2: 143,749,115		probably null	Het
Pde5a	T	C	3: 122,817,955	I514T	probably benign	Het
Pign	A	G	1: 105,589,063	W585R	possibly damaging	Het
Pomgnt1	A	G	4: 116,155,736	S407G	probably benign	Het
Ppfia3	G	A	7: 45,353,616	T372I	probably damaging	Het
Prrc2b	A	T	2: 32,212,132	E739V	probably damaging	Het
Scn7a	T	C	2: 66,743,703	E192G	probably damaging	Het
Slmap	T	C	14: 26,462,280	D316G	probably damaging	Het
Smim8	GGTTTAATGAAGAG	GG	4: 34,771,259		probably benign	Het
Smim8	TTTAATGAAGAGCT	TT	4: 34,771,261		probably benign	Het
Tgm2	T	A	2: 158,143,054	Y44F	possibly damaging	Het
Tmc8	C	A	11: 117,792,629	S670*	probably null	Het
Tmem145	A	G	7: 25,315,521	D523G	probably benign	Het
Trove2	A	G	1: 143,766,765	V209A	probably benign	Het
Vmn2r115	G	A	17: 23,347,963	G483E	probably damaging	Het

Other mutations in Clasp1

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL01785:Clasp1	APN	1	118497736	missense	possibly damaging	0.74
IGL01786:Clasp1	APN	1	118497736	missense	possibly damaging	0.74
IGL01871:Clasp1	APN	1	118570889	missense	probably damaging	1.00
IGL02066:Clasp1	APN	1	118565260	critical splice donor site	probably null
IGL02602:Clasp1	APN	1	118471785	missense	probably damaging	0.99
IGL02683:Clasp1	APN	1	118539266	missense	probably benign	0.33
IGL02728:Clasp1	APN	1	118602377	missense	probably damaging	1.00
IGL02820:Clasp1	APN	1	118551104	missense	possibly damaging	0.77
IGL02874:Clasp1	APN	1	118552043	missense	possibly damaging	0.86
IGL02975:Clasp1	APN	1	118462547	missense	probably damaging	1.00
IGL03100:Clasp1	APN	1	118467896	missense	possibly damaging	0.79
IGL03115:Clasp1	APN	1	118501323	nonsense	probably null
IGL03122:Clasp1	APN	1	118510277	missense	probably damaging	1.00
IGL03180:Clasp1	APN	1	118505525	missense	probably benign	0.33
IGL03248:Clasp1	APN	1	118602476	missense	probably benign	0.01
IGL03388:Clasp1	APN	1	118505503	missense	possibly damaging	0.95
F5770:Clasp1	UTSW	1	118581348	missense	probably damaging	1.00
I2288:Clasp1	UTSW	1	118565229	missense	probably benign	0.09
PIT4585001:Clasp1	UTSW	1	118462555	missense	probably damaging	0.99
R0079:Clasp1	UTSW	1	118543304	missense	probably damaging	1.00
R0395:Clasp1	UTSW	1	118539331	missense	possibly damaging	0.48
R0960:Clasp1	UTSW	1	118552026	missense	probably benign	0.39
R1448:Clasp1	UTSW	1	118508916	missense	probably benign	0.01
R1497:Clasp1	UTSW	1	118552058	missense	probably benign	0.42
R1607:Clasp1	UTSW	1	118504959	missense	probably damaging	0.98
R1722:Clasp1	UTSW	1	118590464	missense	probably damaging	1.00
R1758:Clasp1	UTSW	1	118548025	missense	probably damaging	1.00
R1765:Clasp1	UTSW	1	118505531	missense	probably damaging	0.99
R1855:Clasp1	UTSW	1	118508894	missense	probably damaging	1.00
R1861:Clasp1	UTSW	1	118570931	missense	possibly damaging	0.93
R1874:Clasp1	UTSW	1	118600585	critical splice donor site	probably null
R1942:Clasp1	UTSW	1	118501348	missense	possibly damaging	0.94
R2025:Clasp1	UTSW	1	118504899	missense	probably damaging	1.00
R2174:Clasp1	UTSW	1	118560095	missense	probably damaging	1.00
R2280:Clasp1	UTSW	1	118565183	missense	probably benign	0.05
R2288:Clasp1	UTSW	1	118578878	missense	probably benign
R2895:Clasp1	UTSW	1	118459838	missense	probably damaging	1.00
R3958:Clasp1	UTSW	1	118467881	missense	probably damaging	0.99
R4073:Clasp1	UTSW	1	118503848	missense	probably damaging	1.00
R4206:Clasp1	UTSW	1	118578906	missense	probably damaging	1.00
R4465:Clasp1	UTSW	1	118561078	missense	probably damaging	1.00
R4609:Clasp1	UTSW	1	118503035	intron	probably benign
R4679:Clasp1	UTSW	1	118543271	missense	probably damaging	0.99
R4707:Clasp1	UTSW	1	118543197	nonsense	probably null
R4809:Clasp1	UTSW	1	118461250	missense	probably benign	0.00
R4906:Clasp1	UTSW	1	118508910	nonsense	probably null
R5048:Clasp1	UTSW	1	118547610	intron	probably benign
R5298:Clasp1	UTSW	1	118547920	missense	possibly damaging	0.71
R5485:Clasp1	UTSW	1	118467913	missense	possibly damaging	0.95
R5516:Clasp1	UTSW	1	118497721	missense	probably damaging	1.00
R5911:Clasp1	UTSW	1	118506908	unclassified	probably benign
R6092:Clasp1	UTSW	1	118510298	missense	probably damaging	0.97
R6181:Clasp1	UTSW	1	118419817	missense	probably benign	0.18
R6478:Clasp1	UTSW	1	118512180	nonsense	probably null
R7090:Clasp1	UTSW	1	118482086	missense	probably benign	0.45
R7216:Clasp1	UTSW	1	118547918	missense	probably benign	0.00
R7508:Clasp1	UTSW	1	118545434	missense	probably benign	0.30
R7541:Clasp1	UTSW	1	118542997	splice site	probably null
R7644:Clasp1	UTSW	1	118512750	splice site	probably null
R7825:Clasp1	UTSW	1	118545393	missense	probably benign	0.00
R7910:Clasp1	UTSW	1	118602414	nonsense	probably null
R7971:Clasp1	UTSW	1	118521829	missense	probably damaging	0.99
R8074:Clasp1	UTSW	1	118462483	missense	probably benign
R8344:Clasp1	UTSW	1	118503899	missense	probably damaging	1.00
V7581:Clasp1	UTSW	1	118581348	missense	probably damaging	1.00
X0028:Clasp1	UTSW	1	118551125	missense	possibly damaging	0.93

Predicted Primers

PCR Primer
(F):5'- CCTGCTCTCTTGGAGTTGAC -3'
(R):5'- GGTTTCTCAGCTCTAATGTCAGC -3'

Sequencing Primer
(F):5'- AGTTGACTGTCCAGCAAGC -3'
(R):5'- CTCAGCTCTAATGTCAGCAGTAGG -3'

Posted On

2016-12-20