Incidental Mutation 'R5840:Syne2'
ID 450393
Institutional Source Beutler Lab
Gene Symbol Syne2
Ensembl Gene ENSMUSG00000063450
Gene Name spectrin repeat containing, nuclear envelope 2
Synonyms syne-2, D12Ertd777e, nesprin-2, 6820443O06Rik, Nesp2g
MMRRC Submission 044060-MU
Accession Numbers

Genbank: NM_001005510
Essential gene? Possibly non essential (E-score: 0.305) question?
Stock # R5840 (G1)
Quality Score 225
Status Validated
Chromosome 12
Chromosomal Location 75818134-76110926 bp(+) (GRCm38)
Type of Mutation splice site
DNA Base Change (assembly) T to A at 75880291 bp (GRCm38)
Zygosity Heterozygous
Amino Acid Change
Ref Sequence ENSEMBL: ENSMUSP00000118142 (fasta)
Gene Model predicted gene model for transcript(s): [ENSMUST00000044217] [ENSMUST00000044217] [ENSMUST00000142864] [ENSMUST00000142864] [ENSMUST00000143031] [ENSMUST00000143031] [ENSMUST00000148324] [ENSMUST00000148324] [ENSMUST00000150317] [ENSMUST00000150317]
AlphaFold no structure available at present
Predicted Effect probably null
Transcript: ENSMUST00000044217
SMART Domains Protein: ENSMUSP00000047697
Gene: ENSMUSG00000063450

DomainStartEndE-ValueType
CH 33 134 7.97e-19 SMART
low complexity region 151 175 N/A INTRINSIC
CH 185 283 1.34e-20 SMART
low complexity region 494 505 N/A INTRINSIC
coiled coil region 541 572 N/A INTRINSIC
low complexity region 665 674 N/A INTRINSIC
coiled coil region 844 869 N/A INTRINSIC
coiled coil region 936 969 N/A INTRINSIC
coiled coil region 1006 1032 N/A INTRINSIC
SPEC 1427 1525 4.96e0 SMART
SPEC 1528 1632 2.48e-1 SMART
coiled coil region 1660 1699 N/A INTRINSIC
SPEC 2034 2131 1.83e0 SMART
coiled coil region 2173 2194 N/A INTRINSIC
low complexity region 2295 2307 N/A INTRINSIC
coiled coil region 2316 2348 N/A INTRINSIC
SPEC 2720 2820 1.44e-5 SMART
coiled coil region 2905 2934 N/A INTRINSIC
coiled coil region 2962 2989 N/A INTRINSIC
coiled coil region 3108 3136 N/A INTRINSIC
low complexity region 3333 3350 N/A INTRINSIC
low complexity region 3514 3523 N/A INTRINSIC
low complexity region 3666 3676 N/A INTRINSIC
coiled coil region 3678 3708 N/A INTRINSIC
coiled coil region 3761 3788 N/A INTRINSIC
coiled coil region 3846 3903 N/A INTRINSIC
coiled coil region 4015 4067 N/A INTRINSIC
low complexity region 4102 4115 N/A INTRINSIC
coiled coil region 4483 4511 N/A INTRINSIC
low complexity region 4557 4569 N/A INTRINSIC
coiled coil region 4655 4688 N/A INTRINSIC
low complexity region 4749 4763 N/A INTRINSIC
SPEC 4827 4926 5.25e-1 SMART
SPEC 4933 5038 2.64e-4 SMART
SPEC 5048 5152 1.47e-2 SMART
SPEC 5159 5259 4.29e0 SMART
SPEC 5263 5371 4.47e0 SMART
low complexity region 5373 5393 N/A INTRINSIC
SPEC 5583 5681 5.7e-1 SMART
Blast:SPEC 5690 5793 2e-53 BLAST
SPEC 5800 5900 2.11e0 SMART
SPEC 5907 6005 6.91e-8 SMART
SPEC 6012 6119 4.45e-11 SMART
SPEC 6126 6228 6.39e-12 SMART
SPEC 6235 6335 7.75e-11 SMART
SPEC 6539 6642 5.53e-7 SMART
SPEC 6649 6753 5.12e-2 SMART
KASH 6817 6874 8.17e-34 SMART
Predicted Effect probably null
Transcript: ENSMUST00000044217
SMART Domains Protein: ENSMUSP00000047697
Gene: ENSMUSG00000063450

DomainStartEndE-ValueType
CH 33 134 7.97e-19 SMART
low complexity region 151 175 N/A INTRINSIC
CH 185 283 1.34e-20 SMART
low complexity region 494 505 N/A INTRINSIC
coiled coil region 541 572 N/A INTRINSIC
low complexity region 665 674 N/A INTRINSIC
coiled coil region 844 869 N/A INTRINSIC
coiled coil region 936 969 N/A INTRINSIC
coiled coil region 1006 1032 N/A INTRINSIC
SPEC 1427 1525 4.96e0 SMART
SPEC 1528 1632 2.48e-1 SMART
coiled coil region 1660 1699 N/A INTRINSIC
SPEC 2034 2131 1.83e0 SMART
coiled coil region 2173 2194 N/A INTRINSIC
low complexity region 2295 2307 N/A INTRINSIC
coiled coil region 2316 2348 N/A INTRINSIC
SPEC 2720 2820 1.44e-5 SMART
coiled coil region 2905 2934 N/A INTRINSIC
coiled coil region 2962 2989 N/A INTRINSIC
coiled coil region 3108 3136 N/A INTRINSIC
low complexity region 3333 3350 N/A INTRINSIC
low complexity region 3514 3523 N/A INTRINSIC
low complexity region 3666 3676 N/A INTRINSIC
coiled coil region 3678 3708 N/A INTRINSIC
coiled coil region 3761 3788 N/A INTRINSIC
coiled coil region 3846 3903 N/A INTRINSIC
coiled coil region 4015 4067 N/A INTRINSIC
low complexity region 4102 4115 N/A INTRINSIC
coiled coil region 4483 4511 N/A INTRINSIC
low complexity region 4557 4569 N/A INTRINSIC
coiled coil region 4655 4688 N/A INTRINSIC
low complexity region 4749 4763 N/A INTRINSIC
SPEC 4827 4926 5.25e-1 SMART
SPEC 4933 5038 2.64e-4 SMART
SPEC 5048 5152 1.47e-2 SMART
SPEC 5159 5259 4.29e0 SMART
SPEC 5263 5371 4.47e0 SMART
low complexity region 5373 5393 N/A INTRINSIC
SPEC 5583 5681 5.7e-1 SMART
Blast:SPEC 5690 5793 2e-53 BLAST
SPEC 5800 5900 2.11e0 SMART
SPEC 5907 6005 6.91e-8 SMART
SPEC 6012 6119 4.45e-11 SMART
SPEC 6126 6228 6.39e-12 SMART
SPEC 6235 6335 7.75e-11 SMART
SPEC 6539 6642 5.53e-7 SMART
SPEC 6649 6753 5.12e-2 SMART
KASH 6817 6874 8.17e-34 SMART
Predicted Effect noncoding transcript
Transcript: ENSMUST00000133623
Predicted Effect probably null
Transcript: ENSMUST00000142864
SMART Domains Protein: ENSMUSP00000119268
Gene: ENSMUSG00000063450

DomainStartEndE-ValueType
CH 33 111 1.88e-1 SMART
Predicted Effect probably null
Transcript: ENSMUST00000142864
SMART Domains Protein: ENSMUSP00000119268
Gene: ENSMUSG00000063450

DomainStartEndE-ValueType
CH 33 111 1.88e-1 SMART
Predicted Effect probably null
Transcript: ENSMUST00000143031
SMART Domains Protein: ENSMUSP00000119120
Gene: ENSMUSG00000063450

DomainStartEndE-ValueType
CH 33 134 7.97e-19 SMART
low complexity region 151 175 N/A INTRINSIC
CH 185 283 1.34e-20 SMART
low complexity region 494 505 N/A INTRINSIC
coiled coil region 541 572 N/A INTRINSIC
coiled coil region 845 870 N/A INTRINSIC
coiled coil region 937 970 N/A INTRINSIC
coiled coil region 1007 1033 N/A INTRINSIC
SPEC 1428 1526 4.96e0 SMART
SPEC 1529 1633 2.48e-1 SMART
coiled coil region 1661 1700 N/A INTRINSIC
SPEC 2035 2132 1.83e0 SMART
coiled coil region 2174 2195 N/A INTRINSIC
low complexity region 2296 2308 N/A INTRINSIC
coiled coil region 2317 2349 N/A INTRINSIC
SPEC 2721 2821 1.44e-5 SMART
coiled coil region 2906 2935 N/A INTRINSIC
coiled coil region 2963 2990 N/A INTRINSIC
coiled coil region 3109 3137 N/A INTRINSIC
low complexity region 3334 3351 N/A INTRINSIC
low complexity region 3515 3524 N/A INTRINSIC
low complexity region 3667 3677 N/A INTRINSIC
coiled coil region 3679 3709 N/A INTRINSIC
coiled coil region 3762 3789 N/A INTRINSIC
coiled coil region 3847 3904 N/A INTRINSIC
coiled coil region 4016 4068 N/A INTRINSIC
low complexity region 4103 4116 N/A INTRINSIC
coiled coil region 4484 4512 N/A INTRINSIC
low complexity region 4558 4570 N/A INTRINSIC
coiled coil region 4656 4689 N/A INTRINSIC
low complexity region 4750 4764 N/A INTRINSIC
SPEC 4828 4927 5.25e-1 SMART
SPEC 4934 5039 2.64e-4 SMART
SPEC 5049 5153 1.47e-2 SMART
SPEC 5160 5260 4.29e0 SMART
SPEC 5264 5372 4.47e0 SMART
low complexity region 5374 5394 N/A INTRINSIC
SPEC 5584 5682 5.7e-1 SMART
Blast:SPEC 5691 5794 2e-53 BLAST
SPEC 5801 5901 2.11e0 SMART
SPEC 5908 6006 6.91e-8 SMART
SPEC 6013 6120 4.45e-11 SMART
SPEC 6127 6229 6.39e-12 SMART
SPEC 6236 6336 7.75e-11 SMART
SPEC 6540 6643 5.53e-7 SMART
SPEC 6650 6754 5.12e-2 SMART
KASH 6813 6870 8.17e-34 SMART
Predicted Effect probably null
Transcript: ENSMUST00000143031
SMART Domains Protein: ENSMUSP00000119120
Gene: ENSMUSG00000063450

DomainStartEndE-ValueType
CH 33 134 7.97e-19 SMART
low complexity region 151 175 N/A INTRINSIC
CH 185 283 1.34e-20 SMART
low complexity region 494 505 N/A INTRINSIC
coiled coil region 541 572 N/A INTRINSIC
coiled coil region 845 870 N/A INTRINSIC
coiled coil region 937 970 N/A INTRINSIC
coiled coil region 1007 1033 N/A INTRINSIC
SPEC 1428 1526 4.96e0 SMART
SPEC 1529 1633 2.48e-1 SMART
coiled coil region 1661 1700 N/A INTRINSIC
SPEC 2035 2132 1.83e0 SMART
coiled coil region 2174 2195 N/A INTRINSIC
low complexity region 2296 2308 N/A INTRINSIC
coiled coil region 2317 2349 N/A INTRINSIC
SPEC 2721 2821 1.44e-5 SMART
coiled coil region 2906 2935 N/A INTRINSIC
coiled coil region 2963 2990 N/A INTRINSIC
coiled coil region 3109 3137 N/A INTRINSIC
low complexity region 3334 3351 N/A INTRINSIC
low complexity region 3515 3524 N/A INTRINSIC
low complexity region 3667 3677 N/A INTRINSIC
coiled coil region 3679 3709 N/A INTRINSIC
coiled coil region 3762 3789 N/A INTRINSIC
coiled coil region 3847 3904 N/A INTRINSIC
coiled coil region 4016 4068 N/A INTRINSIC
low complexity region 4103 4116 N/A INTRINSIC
coiled coil region 4484 4512 N/A INTRINSIC
low complexity region 4558 4570 N/A INTRINSIC
coiled coil region 4656 4689 N/A INTRINSIC
low complexity region 4750 4764 N/A INTRINSIC
SPEC 4828 4927 5.25e-1 SMART
SPEC 4934 5039 2.64e-4 SMART
SPEC 5049 5153 1.47e-2 SMART
SPEC 5160 5260 4.29e0 SMART
SPEC 5264 5372 4.47e0 SMART
low complexity region 5374 5394 N/A INTRINSIC
SPEC 5584 5682 5.7e-1 SMART
Blast:SPEC 5691 5794 2e-53 BLAST
SPEC 5801 5901 2.11e0 SMART
SPEC 5908 6006 6.91e-8 SMART
SPEC 6013 6120 4.45e-11 SMART
SPEC 6127 6229 6.39e-12 SMART
SPEC 6236 6336 7.75e-11 SMART
SPEC 6540 6643 5.53e-7 SMART
SPEC 6650 6754 5.12e-2 SMART
KASH 6813 6870 8.17e-34 SMART
Predicted Effect probably null
Transcript: ENSMUST00000148324
SMART Domains Protein: ENSMUSP00000121517
Gene: ENSMUSG00000063450

DomainStartEndE-ValueType
Pfam:CH 34 82 1.9e-6 PFAM
Predicted Effect probably null
Transcript: ENSMUST00000148324
SMART Domains Protein: ENSMUSP00000121517
Gene: ENSMUSG00000063450

DomainStartEndE-ValueType
Pfam:CH 34 82 1.9e-6 PFAM
Predicted Effect probably null
Transcript: ENSMUST00000150317
SMART Domains Protein: ENSMUSP00000118142
Gene: ENSMUSG00000063450

DomainStartEndE-ValueType
CH 33 134 7.97e-19 SMART
low complexity region 151 175 N/A INTRINSIC
CH 185 283 1.34e-20 SMART
Blast:SPEC 394 493 2e-27 BLAST
low complexity region 494 505 N/A INTRINSIC
Predicted Effect probably null
Transcript: ENSMUST00000150317
SMART Domains Protein: ENSMUSP00000118142
Gene: ENSMUSG00000063450

DomainStartEndE-ValueType
CH 33 134 7.97e-19 SMART
low complexity region 151 175 N/A INTRINSIC
CH 185 283 1.34e-20 SMART
Blast:SPEC 394 493 2e-27 BLAST
low complexity region 494 505 N/A INTRINSIC
Predicted Effect noncoding transcript
Transcript: ENSMUST00000157033
Meta Mutation Damage Score 0.9755 question?
Coding Region Coverage
  • 1x: 99.8%
  • 3x: 99.3%
  • 10x: 96.5%
  • 20x: 88.1%
Validation Efficiency 99% (75/76)
MGI Phenotype FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] The protein encoded by this gene is a nuclear outer membrane protein that binds cytoplasmic F-actin. This binding tethers the nucleus to the cytoskeleton and aids in the maintenance of the structural integrity of the nucleus. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2009]
PHENOTYPE: Homozygotes for one knock-out allele show normal myonuclear positioning of both synaptic and non-synaptic nuclei in skeletal muscle cells. Homozygotes for another knock-out allele exhibit a thickened epidermis and altered nuclear envelope architecture inprimary dermal fibroblasts and keratinocytes. Mice homozygous for a spontaneous mutation exhibit early retinal defects in photoreceptors, secondary Neurons, and muller glia. [provided by MGI curators]
Allele List at MGI

 All alleles(5) : Targeted, knock-out(2) Gene trapped(3)
Other mutations in this stock
Total: 60 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
Abca2 G A 2: 25,433,359 (GRCm38) R113Q probably benign Het
Aip G A 19: 4,116,010 (GRCm38) P147L possibly damaging Het
Anapc1 A C 2: 128,607,037 (GRCm38) probably benign Het
Arhgap42 C T 9: 9,046,517 (GRCm38) V240I possibly damaging Het
Axdnd1 T C 1: 156,348,958 (GRCm38) E684G probably damaging Het
BC005624 G A 2: 30,981,857 (GRCm38) R2W probably benign Het
Cd177 T G 7: 24,758,070 (GRCm38) Q182P probably damaging Het
Cdca5 G A 19: 6,090,369 (GRCm38) E187K possibly damaging Het
Chmp1a T C 8: 123,208,100 (GRCm38) Q39R probably benign Het
Dab2ip A G 2: 35,727,499 (GRCm38) I1079V probably damaging Het
Dip2c A T 13: 9,506,676 (GRCm38) E85D possibly damaging Het
Elmo2 A T 2: 165,295,552 (GRCm38) S497R possibly damaging Het
Ephb6 C T 6: 41,615,573 (GRCm38) A339V possibly damaging Het
Foxred1 T C 9: 35,210,139 (GRCm38) K38E probably damaging Het
Frem2 T A 3: 53,647,921 (GRCm38) T1732S probably damaging Het
Fto A G 8: 91,666,440 (GRCm38) probably benign Het
Gm17430 T A 18: 9,726,528 (GRCm38) Q48L probably damaging Het
Gng2 A G 14: 19,875,814 (GRCm38) I70T probably damaging Het
Gtf2a2 A G 9: 70,015,293 (GRCm38) probably benign Het
Invs A G 4: 48,396,284 (GRCm38) D263G probably damaging Het
Itga2b C T 11: 102,461,331 (GRCm38) V475M probably damaging Het
Kansl1l A G 1: 66,770,215 (GRCm38) probably benign Het
Klhl25 T C 7: 75,866,692 (GRCm38) F449L possibly damaging Het
Lamb1 T A 12: 31,266,756 (GRCm38) C83S probably damaging Het
Loxl4 G T 19: 42,598,715 (GRCm38) T648K probably damaging Het
Lrit2 T C 14: 37,069,005 (GRCm38) F214L possibly damaging Het
N4bp2 T G 5: 65,808,094 (GRCm38) L1162R probably damaging Het
Naa40 A T 19: 7,230,008 (GRCm38) I117N probably benign Het
Ncapd3 T C 9: 27,094,758 (GRCm38) S1492P probably benign Het
Nf2 T A 11: 4,816,146 (GRCm38) D128V probably benign Het
Nox4 T C 7: 87,360,793 (GRCm38) S401P probably benign Het
Nt5c1b T C 12: 10,377,171 (GRCm38) V323A probably damaging Het
Olfr1474 G A 19: 13,471,878 (GRCm38) V303I probably benign Het
Olfr601 T A 7: 103,358,369 (GRCm38) H275L probably damaging Het
Olfr622 C T 7: 103,639,256 (GRCm38) V295I probably benign Het
Pcdhb14 T C 18: 37,448,750 (GRCm38) V303A probably benign Het
Pde8a C A 7: 81,213,965 (GRCm38) H17Q probably benign Het
Pfkl C T 10: 77,988,724 (GRCm38) V716I probably benign Het
Phc3 G A 3: 30,936,583 (GRCm38) S495L possibly damaging Het
Psg18 A G 7: 18,346,602 (GRCm38) probably benign Het
Rcc2 T G 4: 140,712,138 (GRCm38) N175K possibly damaging Het
Rhot2 G A 17: 25,840,058 (GRCm38) T276I probably benign Het
Rnase9 A T 14: 51,038,988 (GRCm38) Y178N probably benign Het
Sema4b T C 7: 80,218,949 (GRCm38) C297R probably damaging Het
Slc35d2 T C 13: 64,118,413 (GRCm38) probably null Het
Sptlc3 A T 2: 139,547,206 (GRCm38) N169Y probably damaging Het
Srsf9 T G 5: 115,331,465 (GRCm38) M29R probably benign Het
Stip1 C A 19: 7,022,068 (GRCm38) D449Y possibly damaging Het
Tgm5 A G 2: 121,085,660 (GRCm38) probably null Het
Thbs2 A T 17: 14,681,430 (GRCm38) probably null Het
Trak2 T C 1: 58,919,273 (GRCm38) E283G probably damaging Het
Trbv21 A G 6: 41,202,858 (GRCm38) Y36C probably damaging Het
Trpm7 A T 2: 126,822,611 (GRCm38) Y949* probably null Het
Ubqln5 T C 7: 104,128,954 (GRCm38) D221G possibly damaging Het
Ubxn4 T A 1: 128,259,525 (GRCm38) V85D possibly damaging Het
Vmn1r172 T A 7: 23,660,175 (GRCm38) W162R probably benign Het
Vrk2 A G 11: 26,534,314 (GRCm38) probably benign Het
Zc3h8 A C 2: 128,929,904 (GRCm38) D276E probably benign Het
Zfp369 C T 13: 65,297,278 (GRCm38) T745I possibly damaging Het
Zfp608 T C 18: 54,898,906 (GRCm38) K654R probably damaging Het
Other mutations in Syne2
AlleleSourceChrCoordTypePredicted EffectPPH Score
IGL00329:Syne2 APN 12 76,031,700 (GRCm38) unclassified probably benign
IGL00595:Syne2 APN 12 75,925,646 (GRCm38) missense possibly damaging 0.76
IGL00672:Syne2 APN 12 76,064,184 (GRCm38) missense probably damaging 1.00
IGL00781:Syne2 APN 12 76,024,062 (GRCm38) missense probably benign 0.00
IGL00823:Syne2 APN 12 75,989,242 (GRCm38) missense probably damaging 0.98
IGL01014:Syne2 APN 12 75,905,277 (GRCm38) missense probably damaging 0.99
IGL01074:Syne2 APN 12 76,031,587 (GRCm38) nonsense probably null
IGL01074:Syne2 APN 12 75,987,011 (GRCm38) missense probably benign 0.00
IGL01324:Syne2 APN 12 76,043,752 (GRCm38) missense probably damaging 1.00
IGL01325:Syne2 APN 12 75,926,514 (GRCm38) missense probably benign 0.01
IGL01331:Syne2 APN 12 75,929,253 (GRCm38) splice site probably benign
IGL01338:Syne2 APN 12 76,060,226 (GRCm38) missense possibly damaging 0.55
IGL01373:Syne2 APN 12 75,987,107 (GRCm38) missense probably damaging 1.00
IGL01446:Syne2 APN 12 76,041,375 (GRCm38) missense probably damaging 1.00
IGL01556:Syne2 APN 12 76,087,815 (GRCm38) missense probably damaging 1.00
IGL01585:Syne2 APN 12 75,949,060 (GRCm38) critical splice acceptor site probably null
IGL01629:Syne2 APN 12 76,004,603 (GRCm38) missense possibly damaging 0.49
IGL01686:Syne2 APN 12 75,909,336 (GRCm38) missense probably benign
IGL01935:Syne2 APN 12 75,925,313 (GRCm38) missense probably damaging 1.00
IGL01941:Syne2 APN 12 75,967,220 (GRCm38) missense probably benign 0.01
IGL01956:Syne2 APN 12 76,097,974 (GRCm38) missense probably damaging 1.00
IGL01967:Syne2 APN 12 75,941,303 (GRCm38) missense probably damaging 1.00
IGL01990:Syne2 APN 12 76,054,933 (GRCm38) missense probably damaging 1.00
IGL02000:Syne2 APN 12 76,015,645 (GRCm38) missense probably damaging 0.99
IGL02063:Syne2 APN 12 76,052,100 (GRCm38) missense probably damaging 0.96
IGL02069:Syne2 APN 12 75,927,412 (GRCm38) missense probably benign 0.13
IGL02120:Syne2 APN 12 75,946,706 (GRCm38) missense probably damaging 1.00
IGL02222:Syne2 APN 12 75,952,843 (GRCm38) missense probably damaging 0.96
IGL02223:Syne2 APN 12 76,108,305 (GRCm38) missense probably benign 0.00
IGL02321:Syne2 APN 12 75,918,999 (GRCm38) missense possibly damaging 0.58
IGL02488:Syne2 APN 12 75,965,738 (GRCm38) missense probably benign 0.24
IGL02491:Syne2 APN 12 76,072,179 (GRCm38) missense probably benign 0.10
IGL02525:Syne2 APN 12 76,101,003 (GRCm38) missense probably damaging 0.99
IGL02578:Syne2 APN 12 76,022,279 (GRCm38) missense possibly damaging 0.76
IGL02615:Syne2 APN 12 76,096,994 (GRCm38) missense probably damaging 1.00
IGL02702:Syne2 APN 12 76,097,924 (GRCm38) missense probably damaging 1.00
IGL02726:Syne2 APN 12 76,015,582 (GRCm38) missense probably damaging 0.99
IGL02795:Syne2 APN 12 75,966,549 (GRCm38) missense probably damaging 0.99
IGL02803:Syne2 APN 12 76,031,546 (GRCm38) missense probably damaging 1.00
IGL02814:Syne2 APN 12 75,945,376 (GRCm38) missense possibly damaging 0.64
IGL03013:Syne2 APN 12 75,929,337 (GRCm38) missense probably benign 0.00
IGL03131:Syne2 APN 12 76,057,490 (GRCm38) missense probably damaging 1.00
IGL03152:Syne2 APN 12 75,965,712 (GRCm38) missense probably benign 0.12
IGL03216:Syne2 APN 12 75,942,961 (GRCm38) splice site probably benign
IGL03228:Syne2 APN 12 75,979,912 (GRCm38) missense probably benign 0.01
IGL03259:Syne2 APN 12 75,989,079 (GRCm38) missense probably benign 0.05
IGL03374:Syne2 APN 12 76,074,586 (GRCm38) missense possibly damaging 0.66
IGL03375:Syne2 APN 12 75,925,435 (GRCm38) missense possibly damaging 0.57
3-1:Syne2 UTSW 12 75,930,632 (GRCm38) missense probably benign 0.02
B5639:Syne2 UTSW 12 75,929,790 (GRCm38) missense probably benign
K3955:Syne2 UTSW 12 75,930,665 (GRCm38) missense probably damaging 1.00
P0026:Syne2 UTSW 12 75,880,220 (GRCm38) splice site probably benign
PIT4514001:Syne2 UTSW 12 76,105,015 (GRCm38) missense probably damaging 0.99
R0089:Syne2 UTSW 12 75,963,876 (GRCm38) missense probably damaging 1.00
R0110:Syne2 UTSW 12 76,097,960 (GRCm38) nonsense probably null
R0113:Syne2 UTSW 12 76,033,722 (GRCm38) missense probably damaging 1.00
R0113:Syne2 UTSW 12 75,930,578 (GRCm38) missense probably damaging 1.00
R0141:Syne2 UTSW 12 75,941,298 (GRCm38) missense probably damaging 1.00
R0211:Syne2 UTSW 12 76,097,957 (GRCm38) missense probably damaging 1.00
R0219:Syne2 UTSW 12 76,042,004 (GRCm38) missense probably damaging 1.00
R0242:Syne2 UTSW 12 76,098,034 (GRCm38) missense probably damaging 1.00
R0242:Syne2 UTSW 12 76,098,034 (GRCm38) missense probably damaging 1.00
R0279:Syne2 UTSW 12 76,095,613 (GRCm38) missense probably damaging 1.00
R0319:Syne2 UTSW 12 76,064,162 (GRCm38) missense probably damaging 0.99
R0325:Syne2 UTSW 12 75,962,641 (GRCm38) missense probably benign 0.00
R0329:Syne2 UTSW 12 75,966,953 (GRCm38) missense probably benign
R0330:Syne2 UTSW 12 75,966,953 (GRCm38) missense probably benign
R0361:Syne2 UTSW 12 75,918,610 (GRCm38) missense probably benign 0.22
R0363:Syne2 UTSW 12 76,072,207 (GRCm38) missense probably damaging 0.98
R0367:Syne2 UTSW 12 75,880,177 (GRCm38) missense probably damaging 1.00
R0371:Syne2 UTSW 12 75,933,845 (GRCm38) missense probably damaging 1.00
R0374:Syne2 UTSW 12 75,921,226 (GRCm38) nonsense probably null
R0388:Syne2 UTSW 12 75,986,975 (GRCm38) missense probably benign 0.41
R0411:Syne2 UTSW 12 76,059,584 (GRCm38) splice site probably null
R0432:Syne2 UTSW 12 75,949,064 (GRCm38) missense probably damaging 0.99
R0469:Syne2 UTSW 12 75,854,149 (GRCm38) critical splice donor site probably null
R0492:Syne2 UTSW 12 75,982,063 (GRCm38) critical splice donor site probably null
R0496:Syne2 UTSW 12 76,038,940 (GRCm38) missense possibly damaging 0.80
R0504:Syne2 UTSW 12 76,033,591 (GRCm38) splice site probably benign
R0505:Syne2 UTSW 12 76,099,464 (GRCm38) missense probably damaging 1.00
R0510:Syne2 UTSW 12 75,854,149 (GRCm38) critical splice donor site probably null
R0518:Syne2 UTSW 12 76,108,862 (GRCm38) critical splice acceptor site probably null
R0539:Syne2 UTSW 12 76,024,121 (GRCm38) missense possibly damaging 0.69
R0552:Syne2 UTSW 12 75,931,004 (GRCm38) missense probably benign 0.00
R0557:Syne2 UTSW 12 75,929,301 (GRCm38) missense probably benign 0.04
R0567:Syne2 UTSW 12 75,890,230 (GRCm38) missense probably damaging 0.98
R0599:Syne2 UTSW 12 76,097,960 (GRCm38) nonsense probably null
R0602:Syne2 UTSW 12 76,097,960 (GRCm38) nonsense probably null
R0608:Syne2 UTSW 12 75,963,813 (GRCm38) missense probably damaging 1.00
R0614:Syne2 UTSW 12 75,912,353 (GRCm38) splice site probably null
R0636:Syne2 UTSW 12 75,930,983 (GRCm38) missense possibly damaging 0.75
R0647:Syne2 UTSW 12 75,888,203 (GRCm38) missense probably benign
R0654:Syne2 UTSW 12 76,097,960 (GRCm38) nonsense probably null
R0658:Syne2 UTSW 12 76,094,336 (GRCm38) missense probably damaging 1.00
R0666:Syne2 UTSW 12 75,923,013 (GRCm38) missense probably damaging 0.99
R0707:Syne2 UTSW 12 75,982,063 (GRCm38) critical splice donor site probably null
R0714:Syne2 UTSW 12 76,097,960 (GRCm38) nonsense probably null
R0841:Syne2 UTSW 12 76,074,435 (GRCm38) splice site probably benign
R0848:Syne2 UTSW 12 76,097,960 (GRCm38) nonsense probably null
R0848:Syne2 UTSW 12 76,097,959 (GRCm38) frame shift probably null
R1077:Syne2 UTSW 12 76,042,035 (GRCm38) missense possibly damaging 0.94
R1103:Syne2 UTSW 12 76,109,835 (GRCm38) missense probably benign 0.00
R1144:Syne2 UTSW 12 75,966,524 (GRCm38) missense probably benign 0.04
R1194:Syne2 UTSW 12 75,934,513 (GRCm38) missense probably damaging 1.00
R1247:Syne2 UTSW 12 75,967,490 (GRCm38) missense probably benign 0.39
R1276:Syne2 UTSW 12 75,941,189 (GRCm38) critical splice acceptor site probably null
R1343:Syne2 UTSW 12 76,033,643 (GRCm38) missense probably damaging 1.00
R1442:Syne2 UTSW 12 75,946,715 (GRCm38) missense probably damaging 1.00
R1448:Syne2 UTSW 12 76,052,178 (GRCm38) missense possibly damaging 0.56
R1448:Syne2 UTSW 12 76,020,325 (GRCm38) splice site probably null
R1522:Syne2 UTSW 12 76,103,783 (GRCm38) missense probably damaging 0.98
R1528:Syne2 UTSW 12 75,966,100 (GRCm38) missense probably benign 0.00
R1636:Syne2 UTSW 12 76,004,732 (GRCm38) missense probably benign 0.01
R1637:Syne2 UTSW 12 75,996,002 (GRCm38) missense probably damaging 1.00
R1650:Syne2 UTSW 12 75,904,259 (GRCm38) nonsense probably null
R1654:Syne2 UTSW 12 76,101,094 (GRCm38) missense possibly damaging 0.56
R1714:Syne2 UTSW 12 76,054,939 (GRCm38) missense probably benign 0.26
R1750:Syne2 UTSW 12 76,052,805 (GRCm38) missense probably damaging 1.00
R1772:Syne2 UTSW 12 75,938,729 (GRCm38) missense probably benign 0.19
R1797:Syne2 UTSW 12 75,963,783 (GRCm38) missense probably benign 0.00
R1830:Syne2 UTSW 12 76,109,862 (GRCm38) missense probably damaging 1.00
R1837:Syne2 UTSW 12 75,967,660 (GRCm38) missense probably damaging 0.99
R1908:Syne2 UTSW 12 76,094,279 (GRCm38) critical splice acceptor site probably null
R1913:Syne2 UTSW 12 75,899,246 (GRCm38) missense possibly damaging 0.60
R1944:Syne2 UTSW 12 76,074,544 (GRCm38) missense probably damaging 1.00
R1950:Syne2 UTSW 12 75,952,870 (GRCm38) missense probably benign
R1958:Syne2 UTSW 12 75,969,545 (GRCm38) missense probably benign 0.11
R2018:Syne2 UTSW 12 76,074,579 (GRCm38) missense probably damaging 1.00
R2037:Syne2 UTSW 12 76,025,569 (GRCm38) missense probably benign 0.04
R2067:Syne2 UTSW 12 75,888,342 (GRCm38) critical splice donor site probably null
R2073:Syne2 UTSW 12 76,015,579 (GRCm38) missense possibly damaging 0.54
R2099:Syne2 UTSW 12 75,979,973 (GRCm38) missense probably benign 0.06
R2102:Syne2 UTSW 12 76,028,079 (GRCm38) missense probably benign 0.01
R2134:Syne2 UTSW 12 75,952,786 (GRCm38) missense probably damaging 0.99
R2135:Syne2 UTSW 12 75,952,786 (GRCm38) missense probably damaging 0.99
R2157:Syne2 UTSW 12 76,094,456 (GRCm38) missense probably damaging 1.00
R2173:Syne2 UTSW 12 76,100,989 (GRCm38) splice site probably benign
R2248:Syne2 UTSW 12 76,096,904 (GRCm38) missense probably damaging 1.00
R2276:Syne2 UTSW 12 75,927,466 (GRCm38) missense possibly damaging 0.87
R2277:Syne2 UTSW 12 75,927,466 (GRCm38) missense possibly damaging 0.87
R2278:Syne2 UTSW 12 75,927,466 (GRCm38) missense possibly damaging 0.87
R2279:Syne2 UTSW 12 75,927,466 (GRCm38) missense possibly damaging 0.87
R2483:Syne2 UTSW 12 76,095,537 (GRCm38) missense probably damaging 1.00
R2877:Syne2 UTSW 12 76,000,831 (GRCm38) missense probably benign 0.00
R2884:Syne2 UTSW 12 75,963,759 (GRCm38) missense probably benign 0.00
R3119:Syne2 UTSW 12 75,909,284 (GRCm38) missense probably benign 0.01
R3499:Syne2 UTSW 12 76,054,978 (GRCm38) splice site probably null
R3827:Syne2 UTSW 12 75,987,031 (GRCm38) missense probably benign 0.02
R3847:Syne2 UTSW 12 76,048,622 (GRCm38) missense probably damaging 1.00
R3849:Syne2 UTSW 12 76,046,065 (GRCm38) nonsense probably null
R3850:Syne2 UTSW 12 76,048,622 (GRCm38) missense probably damaging 1.00
R3859:Syne2 UTSW 12 75,929,784 (GRCm38) missense possibly damaging 0.55
R3861:Syne2 UTSW 12 75,966,479 (GRCm38) missense probably damaging 0.98
R4078:Syne2 UTSW 12 76,035,624 (GRCm38) missense probably damaging 1.00
R4116:Syne2 UTSW 12 75,931,079 (GRCm38) missense probably damaging 1.00
R4326:Syne2 UTSW 12 75,952,742 (GRCm38) missense probably damaging 1.00
R4335:Syne2 UTSW 12 76,028,092 (GRCm38) missense probably damaging 1.00
R4410:Syne2 UTSW 12 76,094,393 (GRCm38) missense probably damaging 1.00
R4412:Syne2 UTSW 12 76,106,060 (GRCm38) missense probably benign 0.01
R4444:Syne2 UTSW 12 76,023,030 (GRCm38) missense probably damaging 1.00
R4595:Syne2 UTSW 12 75,967,071 (GRCm38) missense possibly damaging 0.88
R4604:Syne2 UTSW 12 75,967,710 (GRCm38) missense probably damaging 0.99
R4606:Syne2 UTSW 12 75,989,253 (GRCm38) missense probably damaging 1.00
R4651:Syne2 UTSW 12 75,989,239 (GRCm38) missense probably damaging 0.99
R4656:Syne2 UTSW 12 76,031,373 (GRCm38) missense probably damaging 1.00
R4675:Syne2 UTSW 12 75,949,301 (GRCm38) missense probably damaging 1.00
R4790:Syne2 UTSW 12 76,020,391 (GRCm38) missense probably benign 0.19
R4791:Syne2 UTSW 12 75,909,244 (GRCm38) missense possibly damaging 0.96
R4799:Syne2 UTSW 12 75,899,167 (GRCm38) missense probably benign 0.04
R4836:Syne2 UTSW 12 75,979,819 (GRCm38) missense probably damaging 1.00
R4880:Syne2 UTSW 12 75,979,819 (GRCm38) missense probably damaging 1.00
R4881:Syne2 UTSW 12 75,979,819 (GRCm38) missense probably damaging 1.00
R4899:Syne2 UTSW 12 75,854,101 (GRCm38) missense probably benign 0.03
R4934:Syne2 UTSW 12 75,899,272 (GRCm38) missense probably benign 0.14
R4981:Syne2 UTSW 12 75,941,219 (GRCm38) missense probably damaging 0.98
R4996:Syne2 UTSW 12 75,943,950 (GRCm38) missense possibly damaging 0.87
R5056:Syne2 UTSW 12 75,909,131 (GRCm38) unclassified probably benign
R5066:Syne2 UTSW 12 75,966,551 (GRCm38) missense probably benign 0.05
R5095:Syne2 UTSW 12 75,952,826 (GRCm38) missense probably damaging 0.99
R5151:Syne2 UTSW 12 76,043,710 (GRCm38) missense probably benign 0.06
R5193:Syne2 UTSW 12 76,094,420 (GRCm38) missense probably damaging 1.00
R5267:Syne2 UTSW 12 75,938,741 (GRCm38) missense possibly damaging 0.74
R5288:Syne2 UTSW 12 76,099,338 (GRCm38) missense possibly damaging 0.94
R5402:Syne2 UTSW 12 76,059,439 (GRCm38) missense probably damaging 0.98
R5434:Syne2 UTSW 12 75,971,875 (GRCm38) missense probably damaging 1.00
R5441:Syne2 UTSW 12 75,989,143 (GRCm38) missense possibly damaging 0.75
R5488:Syne2 UTSW 12 75,888,172 (GRCm38) missense probably benign 0.13
R5497:Syne2 UTSW 12 75,880,389 (GRCm38) missense probably benign 0.19
R5506:Syne2 UTSW 12 75,938,721 (GRCm38) missense probably benign 0.01
R5509:Syne2 UTSW 12 75,921,244 (GRCm38) missense probably damaging 1.00
R5518:Syne2 UTSW 12 75,945,170 (GRCm38) missense possibly damaging 0.88
R5561:Syne2 UTSW 12 76,094,458 (GRCm38) nonsense probably null
R5581:Syne2 UTSW 12 75,945,085 (GRCm38) missense probably benign 0.01
R5625:Syne2 UTSW 12 76,095,112 (GRCm38) missense probably benign 0.06
R5642:Syne2 UTSW 12 75,918,532 (GRCm38) missense probably damaging 1.00
R5665:Syne2 UTSW 12 76,108,217 (GRCm38) critical splice donor site probably null
R5666:Syne2 UTSW 12 75,950,959 (GRCm38) missense probably benign 0.16
R5670:Syne2 UTSW 12 75,950,959 (GRCm38) missense probably benign 0.16
R5691:Syne2 UTSW 12 76,027,856 (GRCm38) frame shift probably null
R5696:Syne2 UTSW 12 75,994,145 (GRCm38) missense probably benign 0.00
R5720:Syne2 UTSW 12 75,967,667 (GRCm38) missense probably benign 0.03
R5739:Syne2 UTSW 12 75,997,465 (GRCm38) missense possibly damaging 0.53
R5846:Syne2 UTSW 12 76,028,124 (GRCm38) missense probably benign 0.01
R5850:Syne2 UTSW 12 76,097,975 (GRCm38) missense probably damaging 1.00
R5889:Syne2 UTSW 12 76,072,252 (GRCm38) nonsense probably null
R5912:Syne2 UTSW 12 75,908,947 (GRCm38) critical splice donor site probably null
R5931:Syne2 UTSW 12 76,008,865 (GRCm38) missense probably benign 0.37
R5985:Syne2 UTSW 12 75,966,159 (GRCm38) missense probably damaging 0.96
R5988:Syne2 UTSW 12 75,929,417 (GRCm38) critical splice donor site probably null
R5990:Syne2 UTSW 12 76,024,144 (GRCm38) missense probably benign 0.10
R6038:Syne2 UTSW 12 75,878,384 (GRCm38) nonsense probably null
R6038:Syne2 UTSW 12 75,878,384 (GRCm38) nonsense probably null
R6132:Syne2 UTSW 12 75,945,147 (GRCm38) missense probably benign 0.14
R6136:Syne2 UTSW 12 75,905,325 (GRCm38) missense probably benign 0.24
R6229:Syne2 UTSW 12 75,921,220 (GRCm38) missense probably benign 0.00
R6252:Syne2 UTSW 12 75,969,436 (GRCm38) missense probably benign 0.39
R6271:Syne2 UTSW 12 75,890,381 (GRCm38) missense probably damaging 1.00
R6320:Syne2 UTSW 12 76,061,650 (GRCm38) missense probably damaging 0.96
R6339:Syne2 UTSW 12 75,989,153 (GRCm38) missense probably benign 0.34
R6380:Syne2 UTSW 12 76,104,980 (GRCm38) missense probably damaging 0.98
R6394:Syne2 UTSW 12 75,990,495 (GRCm38) missense probably benign 0.09
R6419:Syne2 UTSW 12 76,096,966 (GRCm38) missense probably damaging 1.00
R6426:Syne2 UTSW 12 75,923,083 (GRCm38) missense probably null 0.97
R6434:Syne2 UTSW 12 76,041,456 (GRCm38) missense probably damaging 0.99
R6437:Syne2 UTSW 12 75,990,414 (GRCm38) missense possibly damaging 0.87
R6466:Syne2 UTSW 12 75,943,901 (GRCm38) missense probably damaging 0.97
R6501:Syne2 UTSW 12 76,027,847 (GRCm38) splice site probably null
R6552:Syne2 UTSW 12 75,890,241 (GRCm38) missense possibly damaging 0.89
R6744:Syne2 UTSW 12 76,074,447 (GRCm38) missense probably damaging 1.00
R6810:Syne2 UTSW 12 75,942,885 (GRCm38) missense probably benign 0.00
R6831:Syne2 UTSW 12 75,966,794 (GRCm38) missense probably benign 0.39
R6861:Syne2 UTSW 12 75,909,266 (GRCm38) missense probably damaging 1.00
R6875:Syne2 UTSW 12 76,035,630 (GRCm38) missense probably damaging 0.99
R6892:Syne2 UTSW 12 75,962,528 (GRCm38) missense probably damaging 0.98
R6899:Syne2 UTSW 12 76,095,729 (GRCm38) splice site probably null
R6906:Syne2 UTSW 12 75,995,986 (GRCm38) missense possibly damaging 0.93
R6909:Syne2 UTSW 12 76,064,195 (GRCm38) missense probably benign 0.04
R6925:Syne2 UTSW 12 75,854,132 (GRCm38) missense possibly damaging 0.58
R6949:Syne2 UTSW 12 75,965,997 (GRCm38) missense probably benign 0.00
R6952:Syne2 UTSW 12 75,927,431 (GRCm38) missense possibly damaging 0.76
R6996:Syne2 UTSW 12 76,028,012 (GRCm38) missense probably damaging 0.99
R7080:Syne2 UTSW 12 76,052,727 (GRCm38) missense probably benign 0.00
R7083:Syne2 UTSW 12 75,943,888 (GRCm38) missense probably damaging 1.00
R7090:Syne2 UTSW 12 75,942,351 (GRCm38) missense probably benign
R7144:Syne2 UTSW 12 76,005,378 (GRCm38) missense probably benign 0.03
R7154:Syne2 UTSW 12 76,059,457 (GRCm38) missense possibly damaging 0.63
R7177:Syne2 UTSW 12 75,971,880 (GRCm38) nonsense probably null
R7190:Syne2 UTSW 12 76,066,587 (GRCm38) missense probably benign 0.01
R7206:Syne2 UTSW 12 76,004,757 (GRCm38) missense probably benign 0.02
R7208:Syne2 UTSW 12 76,031,398 (GRCm38) splice site probably null
R7230:Syne2 UTSW 12 75,933,900 (GRCm38) missense probably benign 0.12
R7260:Syne2 UTSW 12 75,945,079 (GRCm38) missense probably damaging 1.00
R7272:Syne2 UTSW 12 76,048,643 (GRCm38) missense probably benign 0.00
R7296:Syne2 UTSW 12 76,103,036 (GRCm38) missense probably benign 0.00
R7322:Syne2 UTSW 12 75,984,024 (GRCm38) missense probably damaging 1.00
R7329:Syne2 UTSW 12 75,966,984 (GRCm38) missense probably benign 0.01
R7332:Syne2 UTSW 12 75,967,755 (GRCm38) critical splice donor site probably null
R7381:Syne2 UTSW 12 75,926,489 (GRCm38) missense probably benign 0.11
R7401:Syne2 UTSW 12 75,967,381 (GRCm38) missense probably damaging 0.98
R7403:Syne2 UTSW 12 75,915,246 (GRCm38) missense not run
R7429:Syne2 UTSW 12 76,040,410 (GRCm38) nonsense probably null
R7429:Syne2 UTSW 12 75,933,996 (GRCm38) missense probably damaging 1.00
R7430:Syne2 UTSW 12 76,040,410 (GRCm38) nonsense probably null
R7430:Syne2 UTSW 12 75,933,996 (GRCm38) missense probably damaging 1.00
R7438:Syne2 UTSW 12 76,015,563 (GRCm38) missense probably benign 0.04
R7447:Syne2 UTSW 12 76,028,079 (GRCm38) missense probably benign 0.01
R7466:Syne2 UTSW 12 76,046,186 (GRCm38) missense possibly damaging 0.92
R7493:Syne2 UTSW 12 75,965,880 (GRCm38) missense probably benign 0.00
R7502:Syne2 UTSW 12 76,094,326 (GRCm38) missense probably damaging 1.00
R7543:Syne2 UTSW 12 75,906,842 (GRCm38) missense possibly damaging 0.93
R7569:Syne2 UTSW 12 75,927,390 (GRCm38) missense probably benign 0.00
R7599:Syne2 UTSW 12 75,966,371 (GRCm38) missense probably benign 0.04
R7618:Syne2 UTSW 12 75,945,334 (GRCm38) missense probably benign 0.01
R7639:Syne2 UTSW 12 75,934,499 (GRCm38) missense probably damaging 1.00
R7698:Syne2 UTSW 12 75,949,064 (GRCm38) missense probably damaging 0.99
R7702:Syne2 UTSW 12 75,990,387 (GRCm38) missense probably benign 0.16
R7737:Syne2 UTSW 12 75,942,848 (GRCm38) missense probably damaging 1.00
R7742:Syne2 UTSW 12 76,059,435 (GRCm38) missense probably benign 0.02
R7753:Syne2 UTSW 12 76,038,923 (GRCm38) missense probably benign 0.43
R7755:Syne2 UTSW 12 75,997,407 (GRCm38) missense probably benign 0.19
R7757:Syne2 UTSW 12 76,061,779 (GRCm38) missense possibly damaging 0.87
R7790:Syne2 UTSW 12 75,929,103 (GRCm38) splice site probably null
R7808:Syne2 UTSW 12 75,983,727 (GRCm38) splice site probably null
R7809:Syne2 UTSW 12 75,967,456 (GRCm38) missense probably benign 0.00
R7811:Syne2 UTSW 12 75,983,727 (GRCm38) splice site probably null
R7834:Syne2 UTSW 12 75,967,247 (GRCm38) missense probably benign 0.00
R7853:Syne2 UTSW 12 76,031,504 (GRCm38) missense probably damaging 1.00
R7867:Syne2 UTSW 12 75,983,727 (GRCm38) splice site probably null
R7896:Syne2 UTSW 12 76,035,623 (GRCm38) missense probably damaging 0.99
R7903:Syne2 UTSW 12 76,064,184 (GRCm38) missense probably damaging 1.00
R7944:Syne2 UTSW 12 75,904,305 (GRCm38) missense probably damaging 0.98
R7945:Syne2 UTSW 12 75,904,305 (GRCm38) missense probably damaging 0.98
R7963:Syne2 UTSW 12 76,020,400 (GRCm38) missense probably benign 0.38
R7996:Syne2 UTSW 12 76,004,667 (GRCm38) missense probably damaging 1.00
R7998:Syne2 UTSW 12 76,087,858 (GRCm38) missense probably damaging 1.00
R8010:Syne2 UTSW 12 75,930,738 (GRCm38) missense probably benign 0.39
R8016:Syne2 UTSW 12 75,942,907 (GRCm38) missense probably benign 0.19
R8140:Syne2 UTSW 12 75,912,353 (GRCm38) missense possibly damaging 0.63
R8141:Syne2 UTSW 12 76,061,668 (GRCm38) missense possibly damaging 0.66
R8206:Syne2 UTSW 12 76,015,591 (GRCm38) missense probably benign 0.03
R8258:Syne2 UTSW 12 75,949,369 (GRCm38) missense possibly damaging 0.95
R8259:Syne2 UTSW 12 75,949,369 (GRCm38) missense possibly damaging 0.95
R8320:Syne2 UTSW 12 76,103,830 (GRCm38) missense probably damaging 0.99
R8464:Syne2 UTSW 12 75,965,772 (GRCm38) missense probably benign 0.39
R8465:Syne2 UTSW 12 75,854,124 (GRCm38) missense possibly damaging 0.92
R8486:Syne2 UTSW 12 76,042,107 (GRCm38) nonsense probably null
R8488:Syne2 UTSW 12 75,965,772 (GRCm38) missense probably benign 0.39
R8511:Syne2 UTSW 12 76,008,873 (GRCm38) missense probably benign 0.03
R8540:Syne2 UTSW 12 76,094,374 (GRCm38) missense probably damaging 1.00
R8711:Syne2 UTSW 12 76,057,484 (GRCm38) missense probably damaging 1.00
R8722:Syne2 UTSW 12 75,925,321 (GRCm38) missense probably benign 0.04
R8827:Syne2 UTSW 12 76,048,583 (GRCm38) missense probably benign 0.00
R8867:Syne2 UTSW 12 75,942,846 (GRCm38) missense probably damaging 1.00
R8878:Syne2 UTSW 12 75,905,293 (GRCm38) missense probably benign
R8924:Syne2 UTSW 12 75,896,670 (GRCm38) missense probably damaging 0.97
R8966:Syne2 UTSW 12 76,099,423 (GRCm38) missense probably damaging 1.00
R9007:Syne2 UTSW 12 76,099,450 (GRCm38) missense possibly damaging 0.82
R9019:Syne2 UTSW 12 75,952,844 (GRCm38) missense possibly damaging 0.93
R9057:Syne2 UTSW 12 75,890,393 (GRCm38) missense probably damaging 1.00
R9067:Syne2 UTSW 12 75,904,220 (GRCm38) missense probably damaging 1.00
R9081:Syne2 UTSW 12 75,969,516 (GRCm38) nonsense probably null
R9091:Syne2 UTSW 12 75,931,060 (GRCm38) missense probably damaging 1.00
R9123:Syne2 UTSW 12 75,994,064 (GRCm38) missense probably damaging 1.00
R9147:Syne2 UTSW 12 75,890,384 (GRCm38) missense probably damaging 1.00
R9148:Syne2 UTSW 12 75,890,384 (GRCm38) missense probably damaging 1.00
R9163:Syne2 UTSW 12 75,962,575 (GRCm38) missense possibly damaging 0.88
R9192:Syne2 UTSW 12 76,109,929 (GRCm38) missense probably damaging 1.00
R9248:Syne2 UTSW 12 76,107,456 (GRCm38) intron probably benign
R9270:Syne2 UTSW 12 75,931,060 (GRCm38) missense probably damaging 1.00
R9292:Syne2 UTSW 12 75,951,049 (GRCm38) missense probably benign
R9397:Syne2 UTSW 12 75,994,075 (GRCm38) missense possibly damaging 0.59
R9454:Syne2 UTSW 12 76,095,070 (GRCm38) nonsense probably null
R9454:Syne2 UTSW 12 76,020,501 (GRCm38) missense probably damaging 0.99
R9478:Syne2 UTSW 12 76,107,613 (GRCm38) missense probably damaging 0.96
R9492:Syne2 UTSW 12 75,949,065 (GRCm38) missense possibly damaging 0.77
R9573:Syne2 UTSW 12 75,880,360 (GRCm38) missense probably damaging 1.00
R9611:Syne2 UTSW 12 76,033,686 (GRCm38) missense probably benign 0.05
R9623:Syne2 UTSW 12 75,939,986 (GRCm38) missense probably benign 0.12
R9647:Syne2 UTSW 12 76,105,101 (GRCm38) missense possibly damaging 0.55
R9652:Syne2 UTSW 12 76,054,846 (GRCm38) missense probably benign 0.00
R9667:Syne2 UTSW 12 75,880,177 (GRCm38) missense probably damaging 1.00
R9701:Syne2 UTSW 12 75,990,423 (GRCm38) missense probably damaging 1.00
R9794:Syne2 UTSW 12 76,000,843 (GRCm38) missense probably benign 0.04
R9802:Syne2 UTSW 12 75,990,423 (GRCm38) missense probably damaging 1.00
X0019:Syne2 UTSW 12 75,973,287 (GRCm38) missense probably benign 0.41
X0026:Syne2 UTSW 12 76,101,016 (GRCm38) missense possibly damaging 0.78
X0061:Syne2 UTSW 12 75,927,511 (GRCm38) critical splice donor site probably null
X0066:Syne2 UTSW 12 76,096,927 (GRCm38) missense probably damaging 1.00
Z1176:Syne2 UTSW 12 76,040,383 (GRCm38) missense possibly damaging 0.48
Z1176:Syne2 UTSW 12 75,967,541 (GRCm38) missense probably benign 0.01
Z1177:Syne2 UTSW 12 75,973,423 (GRCm38) missense probably damaging 1.00
Z1177:Syne2 UTSW 12 76,097,974 (GRCm38) missense probably damaging 1.00
Z1177:Syne2 UTSW 12 76,064,138 (GRCm38) missense possibly damaging 0.51
Predicted Primers PCR Primer
(F):5'- TTCTTTGGCAGCACACACC -3'
(R):5'- GGGTTTCCTTCTACAATGTCAGC -3'

Sequencing Primer
(F):5'- GCACACACCTCCCTCAGTTG -3'
(R):5'- TGTCAGCAACATGGATATTTATTAGC -3'
Posted On 2016-12-20