Incidental Mutation 'IGL00467:Tas2r109'
List |< first << previous [record 25 of 32] next >> last >|
ID45054
Institutional Source Australian Phenomics Network (link to record)
Gene Symbol Tas2r109
Ensembl Gene ENSMUSG00000062528
Gene Nametaste receptor, type 2, member 109
Synonymsmt2r62, T2R09, Tas2r9, mGR09
Accession Numbers
Is this an essential gene? Probably non essential (E-score: 0.054) question?
Stock #IGL00467
Quality Score
Status
Chromosome6
Chromosomal Location132980015-132980965 bp(-) (GRCm38)
Type of Mutationmissense
DNA Base Change (assembly) C to A at 132980023 bp
ZygosityHeterozygous
Amino Acid Change Valine to Leucine at position 315 (V315L)
Ref Sequence ENSEMBL: ENSMUSP00000069300 (fasta)
Gene Model predicted gene model for transcript(s): [ENSMUST00000067539]
Predicted Effect probably benign
Transcript: ENSMUST00000067539
AA Change: V315L

PolyPhen 2 Score 0.037 (Sensitivity: 0.94; Specificity: 0.82)
SMART Domains Protein: ENSMUSP00000069300
Gene: ENSMUSG00000062528
AA Change: V315L

DomainStartEndE-ValueType
Pfam:TAS2R 9 309 4.3e-81 PFAM
Coding Region Coverage
Validation Efficiency
Allele List at MGI
Other mutations in this stock
Total: 31 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
Abca9 T C 11: 110,145,670 probably benign Het
Acvrl1 C A 15: 101,143,340 probably null Het
Ahnak T A 19: 9,007,223 M1957K probably damaging Het
Brinp3 A G 1: 146,901,774 D653G probably damaging Het
Dcstamp T A 15: 39,754,416 C74S probably benign Het
Esrrg A G 1: 188,210,910 E360G probably damaging Het
Fam13a C T 6: 58,940,113 probably benign Het
Fam208a A G 14: 27,448,164 N350S probably benign Het
Glipr1l1 A G 10: 112,078,381 T216A probably benign Het
Lama2 T A 10: 27,467,197 probably benign Het
Men1 G A 19: 6,337,207 probably null Het
Mta3 T A 17: 83,755,684 probably benign Het
Nfu1 A G 6: 87,020,773 M213V possibly damaging Het
Pam A T 1: 97,924,427 probably benign Het
Pcca A T 14: 122,582,629 M62L probably benign Het
Phf6 A G X: 52,931,646 Y25C probably damaging Het
Phlpp2 C T 8: 109,925,790 H589Y probably benign Het
Ppp1r13b A G 12: 111,829,370 I956T probably damaging Het
Prkcd G A 14: 30,602,422 probably benign Het
Rapgef4 A T 2: 72,256,312 N973I possibly damaging Het
Rnf20 G T 4: 49,655,480 E905* probably null Het
Slc26a6 T A 9: 108,855,889 D22E probably benign Het
Sp2 C T 11: 96,954,561 R578H probably damaging Het
Taf6l A T 19: 8,783,388 N57K probably benign Het
Tex9 T C 9: 72,477,835 T240A probably benign Het
Trank1 G A 9: 111,364,666 probably benign Het
Trim30c A T 7: 104,382,182 Y475* probably null Het
Trim60 T C 8: 65,000,719 T293A possibly damaging Het
Ttc21b T C 2: 66,188,364 Y1233C probably damaging Het
Wdr75 A G 1: 45,802,075 I106V probably benign Het
Zkscan16 T C 4: 58,957,709 S664P possibly damaging Het
Other mutations in Tas2r109
AlleleSourceChrCoordTypePredicted EffectPPH Score
IGL01837:Tas2r109 APN 6 132980514 missense probably benign 0.27
IGL02094:Tas2r109 APN 6 132980239 missense possibly damaging 0.78
R0788:Tas2r109 UTSW 6 132980301 missense probably benign 0.01
R0849:Tas2r109 UTSW 6 132980893 missense probably benign 0.00
R1542:Tas2r109 UTSW 6 132980910 missense possibly damaging 0.93
R1583:Tas2r109 UTSW 6 132980426 missense probably benign 0.01
R2035:Tas2r109 UTSW 6 132980460 missense probably benign
R3845:Tas2r109 UTSW 6 132980803 missense probably damaging 0.99
R4060:Tas2r109 UTSW 6 132980185 missense probably damaging 1.00
R4355:Tas2r109 UTSW 6 132980181 missense probably benign
R5353:Tas2r109 UTSW 6 132980631 missense possibly damaging 0.61
R5860:Tas2r109 UTSW 6 132980701 missense probably benign 0.06
R6211:Tas2r109 UTSW 6 132980624 nonsense probably null
R6378:Tas2r109 UTSW 6 132980881 missense probably benign 0.00
R6861:Tas2r109 UTSW 6 132980085 missense probably benign 0.43
R7319:Tas2r109 UTSW 6 132980700 missense probably benign 0.33
R8553:Tas2r109 UTSW 6 132980208 missense probably benign 0.33
Z1088:Tas2r109 UTSW 6 132980301 missense probably benign 0.07
Posted On2013-06-11