Mutagenetix > Incidental Mutation

Incidental Mutation 'R5698:Fcgbp'

450789

Institutional Source

Beutler Lab

Gene Symbol

Fcgbp

Ensembl Gene

ENSMUSG00000047730

Gene Name

Fc fragment of IgG binding protein

Synonyms

A430096B05Rik

Accession Numbers

Essential gene?

Non essential (E-score: 0.000) question?

Stock #

R5698 (G1)

Quality Score

225

Status

Not validated

Chromosome

Chromosomal Location

28071236-28120862 bp(+) (GRCm38)

Type of Mutation

missense

DNA Base Change (assembly)

A to G at 28092022 bp (GRCm38)

Zygosity

Heterozygous

Amino Acid Change

Threonine to Alanine at position 903 (T903A)

Ref Sequence

ENSEMBL: ENSMUSP00000114271 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000076648] [ENSMUST00000138392]

AlphaFold

E9Q0B5

Predicted Effect

possibly damaging
Transcript: ENSMUST00000076648
AA Change: T903A

PolyPhen 2 Score 0.901 (Sensitivity: 0.82; Specificity: 0.94)

SMART Domains

Protein: ENSMUSP00000075945
Gene: ENSMUSG00000047730
AA Change: T903A

Domain	Start	End	E-Value	Type
signal peptide	1	26	N/A	INTRINSIC
FOLN	27	49	2.3e-4	SMART
VWD	46	211	5.26e-45	SMART
low complexity region	226	237	N/A	INTRINSIC
C8	251	326	1.17e-34	SMART
Pfam:TIL	329	383	1.2e-12	PFAM
VWC	385	431	2.34e-1	SMART
FOLN	418	441	3.48e1	SMART
VWD	438	603	6.85e-35	SMART
C8	642	717	1.4e-32	SMART
Pfam:TIL	720	773	4.7e-14	PFAM
VWC	775	829	9.42e-1	SMART
VWD	824	990	7.86e-44	SMART
C8	1034	1109	1.66e-34	SMART
Pfam:TIL	1112	1165	6.7e-13	PFAM
VWC	1167	1225	9.8e-3	SMART
FOLN	1198	1220	9.55e-1	SMART
FOLN	1224	1246	2.41e0	SMART
VWD	1243	1411	6.59e-37	SMART
C8	1451	1527	5.6e-32	SMART
low complexity region	1541	1551	N/A	INTRINSIC
EGF_like	1558	1581	6.15e1	SMART
VWC	1589	1682	1.6e-2	SMART
VWD	1640	1807	5.15e-39	SMART
C8	1839	1914	4.62e-33	SMART
EGF_like	1942	1965	4.46e1	SMART
VWC	1972	2064	1.92e-1	SMART
VWD	2024	2180	6.34e-39	SMART
low complexity region	2201	2214	N/A	INTRINSIC
C8	2221	2296	3.7e-32	SMART
Pfam:TIL	2299	2352	5e-12	PFAM
VWC	2354	2413	8.29e-1	SMART
FOLN	2385	2407	4.96e1	SMART
VWD	2404	2566	1.89e-5	SMART

Predicted Effect

possibly damaging
Transcript: ENSMUST00000138392
AA Change: T903A

PolyPhen 2 Score 0.954 (Sensitivity: 0.79; Specificity: 0.95)

SMART Domains

Protein: ENSMUSP00000114271
Gene: ENSMUSG00000047730
AA Change: T903A

Domain	Start	End	E-Value	Type
signal peptide	1	26	N/A	INTRINSIC
FOLN	27	49	2.3e-4	SMART
VWD	46	211	5.26e-45	SMART
low complexity region	226	237	N/A	INTRINSIC
C8	251	326	1.17e-34	SMART
Pfam:TIL	329	383	8.4e-13	PFAM
VWC	385	431	2.34e-1	SMART
FOLN	418	441	3.48e1	SMART
VWD	438	603	7.99e-36	SMART
C8	642	717	1.4e-32	SMART
Pfam:TIL	720	773	3.3e-14	PFAM
VWC	775	829	9.42e-1	SMART
VWD	824	990	7.86e-44	SMART
C8	1034	1109	1.66e-34	SMART
Pfam:TIL	1112	1165	6.9e-13	PFAM
VWC	1167	1225	9.8e-3	SMART
FOLN	1198	1220	9.55e-1	SMART
FOLN	1224	1246	2.41e0	SMART
VWD	1243	1411	6.59e-37	SMART
C8	1451	1527	5.6e-32	SMART
low complexity region	1541	1551	N/A	INTRINSIC
EGF_like	1558	1581	6.15e1	SMART
VWC	1589	1682	1.6e-2	SMART
VWD	1640	1807	5.15e-39	SMART
C8	1839	1914	4.62e-33	SMART
EGF_like	1942	1965	4.46e1	SMART
VWC	1972	2064	1.92e-1	SMART
VWD	2024	2180	6.34e-39	SMART
low complexity region	2201	2214	N/A	INTRINSIC
C8	2221	2296	3.7e-32	SMART
Pfam:TIL	2299	2352	1e-11	PFAM
VWC	2354	2413	8.29e-1	SMART
FOLN	2385	2407	4.96e1	SMART
VWD	2404	2566	1.89e-5	SMART

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000140004

Coding Region Coverage

1x: 99.2%
3x: 98.6%
10x: 97.3%
20x: 95.4%

Validation Efficiency

Allele List at MGI

Other mutations in this stock

Total: 56 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
4930556J24Rik	A	G	11: 3,976,366 (GRCm38)	K334E	possibly damaging	Het
Ache	G	A	5: 137,290,559 (GRCm38)	V176M	probably damaging	Het
Acss3	T	C	10: 106,948,744 (GRCm38)	D539G	probably damaging	Het
Adam6b	T	A	12: 113,491,463 (GRCm38)	D633E	probably benign	Het
Aldh16a1	G	A	7: 45,154,407 (GRCm38)		probably benign	Het
Amigo2	G	A	15: 97,245,726 (GRCm38)	Q272*	probably null	Het
Appbp2	A	T	11: 85,210,099 (GRCm38)	H171Q	probably damaging	Het
Arhgef18	A	G	8: 3,439,499 (GRCm38)	D277G	probably damaging	Het
Armc8	A	G	9: 99,535,820 (GRCm38)	V95A	probably benign	Het
Atp6v0a4	C	T	6: 38,050,507 (GRCm38)		probably null	Het
Atp8a1	A	T	5: 67,767,153 (GRCm38)	N289K	probably benign	Het
Cand2	C	T	6: 115,791,743 (GRCm38)	L505F	probably damaging	Het
Ccnt2	A	G	1: 127,803,228 (GRCm38)	K614R	probably benign	Het
Col25a1	A	G	3: 130,478,983 (GRCm38)		probably null	Het
Copa	T	A	1: 172,118,944 (GRCm38)	L976*	probably null	Het
Ddx39b	T	C	17: 35,251,311 (GRCm38)	V267A	probably benign	Het
Doxl2	A	G	6: 48,976,322 (GRCm38)	T394A	possibly damaging	Het
Dpp4	T	A	2: 62,334,311 (GRCm38)	Q709L	probably damaging	Het
Eno4	A	G	19: 58,968,472 (GRCm38)		probably null	Het
Exoc3	A	G	13: 74,174,015 (GRCm38)	L647P	probably benign	Het
Eya4	T	C	10: 23,140,077 (GRCm38)	S308G	possibly damaging	Het
Fbxo41	T	C	6: 85,477,656 (GRCm38)	T693A	possibly damaging	Het
Fkbp10	G	T	11: 100,423,526 (GRCm38)	W384L	probably damaging	Het
Frem2	A	G	3: 53,652,505 (GRCm38)	I1527T	possibly damaging	Het
Gm14124	C	T	2: 150,269,474 (GRCm38)	H695Y	possibly damaging	Het
H13	T	A	2: 152,688,955 (GRCm38)	I220N	probably damaging	Het
Has2	T	C	15: 56,667,916 (GRCm38)	R468G	probably damaging	Het
Ighmbp2	A	G	19: 3,274,538 (GRCm38)	S243P	probably damaging	Het
Irs1	T	C	1: 82,288,734 (GRCm38)	H587R	probably benign	Het
Kcnk1	C	T	8: 126,025,405 (GRCm38)	T250M	probably damaging	Het
Kif9	T	C	9: 110,510,464 (GRCm38)	V458A	probably benign	Het
Krt14	T	C	11: 100,205,625 (GRCm38)	T208A	probably benign	Het
Mybpc3	C	A	2: 91,124,849 (GRCm38)	H349Q	possibly damaging	Het
Neurl3	T	A	1: 36,266,506 (GRCm38)	T207S	possibly damaging	Het
Nol9	T	C	4: 152,050,574 (GRCm38)	V388A	probably damaging	Het
Notch3	T	C	17: 32,157,987 (GRCm38)	N315D	probably damaging	Het
Oas1h	G	T	5: 120,870,982 (GRCm38)	A252S	probably damaging	Het
Olfr156	C	A	4: 43,821,183 (GRCm38)	M59I	probably damaging	Het
Pcbp1	G	A	6: 86,525,152 (GRCm38)	T255M	possibly damaging	Het
Plec	A	G	15: 76,199,608 (GRCm38)	V18A	probably benign	Het
Ppp1r17	A	T	6: 56,026,544 (GRCm38)	E114V	probably damaging	Het
Scamp5	A	T	9: 57,445,433 (GRCm38)	M151K	possibly damaging	Het
Sestd1	T	C	2: 77,218,168 (GRCm38)	Y135C	possibly damaging	Het
Slc22a21	T	G	11: 53,951,349 (GRCm38)	K534N	probably benign	Het
Slc25a12	T	C	2: 71,282,573 (GRCm38)	E448G	probably damaging	Het
Slco3a1	A	G	7: 74,346,818 (GRCm38)	L280P	probably damaging	Het
Sppl2b	C	A	10: 80,866,045 (GRCm38)		probably null	Het
Srd5a2	T	C	17: 74,027,019 (GRCm38)	E135G	possibly damaging	Het
Tfg	A	T	16: 56,701,104 (GRCm38)	M183K	probably damaging	Het
Ticrr	G	A	7: 79,679,133 (GRCm38)	M673I	probably benign	Het
Tm4sf20	T	G	1: 82,768,237 (GRCm38)	M61L	probably benign	Het
Ttll8	A	T	15: 88,939,006 (GRCm38)	S85T	possibly damaging	Het
Uggt2	G	A	14: 119,042,726 (GRCm38)	S780F	probably damaging	Het
Uroc1	T	C	6: 90,347,320 (GRCm38)	L442P	probably damaging	Het
Znrf3	A	G	11: 5,289,006 (GRCm38)		probably benign	Het
Zswim2	C	A	2: 83,925,183 (GRCm38)	D125Y	possibly damaging	Het

Other mutations in Fcgbp

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00309:Fcgbp	APN	7	28,085,130 (GRCm38)	missense	probably damaging	1.00
IGL00331:Fcgbp	APN	7	28,101,541 (GRCm38)	splice site	probably benign
IGL00335:Fcgbp	APN	7	28,086,135 (GRCm38)	missense	possibly damaging	0.90
IGL00470:Fcgbp	APN	7	28,075,086 (GRCm38)	nonsense	probably null
IGL00491:Fcgbp	APN	7	28,093,402 (GRCm38)	missense	probably damaging	1.00
IGL00498:Fcgbp	APN	7	28,091,797 (GRCm38)	missense	probably damaging	1.00
IGL01296:Fcgbp	APN	7	28,089,647 (GRCm38)	missense	probably benign	0.15
IGL01582:Fcgbp	APN	7	28,093,642 (GRCm38)	missense	probably benign	0.19
IGL01929:Fcgbp	APN	7	28,103,963 (GRCm38)	missense	probably damaging	1.00
IGL02024:Fcgbp	APN	7	28,106,374 (GRCm38)	missense	probably damaging	1.00
IGL02027:Fcgbp	APN	7	28,075,204 (GRCm38)	missense	probably damaging	1.00
IGL02140:Fcgbp	APN	7	28,091,954 (GRCm38)	missense	probably damaging	1.00
IGL02162:Fcgbp	APN	7	28,075,235 (GRCm38)	missense	probably damaging	1.00
IGL02345:Fcgbp	APN	7	28,071,643 (GRCm38)	splice site	probably benign
IGL02377:Fcgbp	APN	7	28,106,970 (GRCm38)	missense	possibly damaging	0.67
IGL02389:Fcgbp	APN	7	28,075,171 (GRCm38)	missense	probably damaging	1.00
IGL02423:Fcgbp	APN	7	28,089,953 (GRCm38)	missense	probably benign	0.02
IGL02523:Fcgbp	APN	7	28,104,732 (GRCm38)	missense	possibly damaging	0.89
IGL02561:Fcgbp	APN	7	28,101,174 (GRCm38)	intron	probably benign
IGL02631:Fcgbp	APN	7	28,085,298 (GRCm38)	missense	probably damaging	1.00
IGL02716:Fcgbp	APN	7	28,101,434 (GRCm38)	missense	probably damaging	0.98
IGL02836:Fcgbp	APN	7	28,117,358 (GRCm38)	missense	possibly damaging	0.91
IGL02957:Fcgbp	APN	7	28,091,847 (GRCm38)	nonsense	probably null
IGL02971:Fcgbp	APN	7	28,101,473 (GRCm38)	missense	probably damaging	1.00
IGL03284:Fcgbp	APN	7	28,085,432 (GRCm38)	missense	possibly damaging	0.93
IGL03379:Fcgbp	APN	7	28,089,917 (GRCm38)	missense	possibly damaging	0.76
bilge	UTSW	7	28,117,337 (GRCm38)	missense	probably benign	0.00
R6548_fcgbp_365	UTSW	7	28,091,918 (GRCm38)	missense	probably benign	0.00
swill	UTSW	7	28,089,734 (GRCm38)	missense	probably damaging	1.00
G1citation:Fcgbp	UTSW	7	28,107,356 (GRCm38)	missense	probably damaging	1.00
IGL02796:Fcgbp	UTSW	7	28,101,151 (GRCm38)	intron	probably benign
PIT4486001:Fcgbp	UTSW	7	28,075,273 (GRCm38)	missense	possibly damaging	0.52
R0277:Fcgbp	UTSW	7	28,085,493 (GRCm38)	critical splice donor site	probably null
R0387:Fcgbp	UTSW	7	28,091,454 (GRCm38)	splice site	probably benign
R0586:Fcgbp	UTSW	7	28,089,713 (GRCm38)	missense	probably damaging	1.00
R0981:Fcgbp	UTSW	7	28,085,110 (GRCm38)	nonsense	probably null
R0987:Fcgbp	UTSW	7	28,094,174 (GRCm38)	missense	probably damaging	1.00
R1240:Fcgbp	UTSW	7	28,120,525 (GRCm38)	missense	probably damaging	1.00
R1394:Fcgbp	UTSW	7	28,093,379 (GRCm38)	missense	probably damaging	0.98
R1395:Fcgbp	UTSW	7	28,093,379 (GRCm38)	missense	probably damaging	0.98
R1438:Fcgbp	UTSW	7	28,103,733 (GRCm38)	nonsense	probably null
R1474:Fcgbp	UTSW	7	28,091,848 (GRCm38)	missense	probably benign	0.00
R1521:Fcgbp	UTSW	7	28,075,160 (GRCm38)	missense	probably benign	0.00
R1740:Fcgbp	UTSW	7	28,101,249 (GRCm38)	missense	possibly damaging	0.87
R1750:Fcgbp	UTSW	7	28,093,443 (GRCm38)	nonsense	probably null
R1772:Fcgbp	UTSW	7	28,105,175 (GRCm38)	missense	possibly damaging	0.90
R1804:Fcgbp	UTSW	7	28,086,139 (GRCm38)	missense	probably benign
R1808:Fcgbp	UTSW	7	28,085,090 (GRCm38)	missense	probably benign	0.04
R1819:Fcgbp	UTSW	7	28,085,283 (GRCm38)	missense	probably benign	0.00
R1934:Fcgbp	UTSW	7	28,107,093 (GRCm38)	missense	probably damaging	1.00
R1972:Fcgbp	UTSW	7	28,094,192 (GRCm38)	missense	probably benign	0.11
R2051:Fcgbp	UTSW	7	28,120,360 (GRCm38)	missense	probably damaging	0.97
R2072:Fcgbp	UTSW	7	28,120,389 (GRCm38)	missense	probably damaging	0.98
R2074:Fcgbp	UTSW	7	28,120,389 (GRCm38)	missense	probably damaging	0.98
R2124:Fcgbp	UTSW	7	28,092,019 (GRCm38)	missense	probably benign	0.03
R2155:Fcgbp	UTSW	7	28,107,203 (GRCm38)	missense	probably benign	0.00
R3015:Fcgbp	UTSW	7	28,075,413 (GRCm38)	splice site	probably benign
R3037:Fcgbp	UTSW	7	28,102,702 (GRCm38)	missense	possibly damaging	0.62
R3151:Fcgbp	UTSW	7	28,117,240 (GRCm38)	missense	probably damaging	1.00
R3176:Fcgbp	UTSW	7	28,091,661 (GRCm38)	missense	probably damaging	0.99
R3177:Fcgbp	UTSW	7	28,091,661 (GRCm38)	missense	probably damaging	0.99
R3276:Fcgbp	UTSW	7	28,091,661 (GRCm38)	missense	probably damaging	0.99
R3277:Fcgbp	UTSW	7	28,091,661 (GRCm38)	missense	probably damaging	0.99
R3623:Fcgbp	UTSW	7	28,101,276 (GRCm38)	missense	probably damaging	1.00
R3730:Fcgbp	UTSW	7	28,085,457 (GRCm38)	missense	possibly damaging	0.82
R3935:Fcgbp	UTSW	7	28,075,399 (GRCm38)	missense	probably benign	0.00
R3936:Fcgbp	UTSW	7	28,075,399 (GRCm38)	missense	probably benign	0.00
R4041:Fcgbp	UTSW	7	28,113,979 (GRCm38)	missense	probably benign	0.01
R4056:Fcgbp	UTSW	7	28,104,116 (GRCm38)	missense	probably benign	0.09
R4057:Fcgbp	UTSW	7	28,104,116 (GRCm38)	missense	probably benign	0.09
R4705:Fcgbp	UTSW	7	28,107,296 (GRCm38)	missense	probably benign	0.44
R4708:Fcgbp	UTSW	7	28,094,961 (GRCm38)	missense	probably benign	0.00
R4710:Fcgbp	UTSW	7	28,094,961 (GRCm38)	missense	probably benign	0.00
R4779:Fcgbp	UTSW	7	28,094,937 (GRCm38)	missense	probably damaging	1.00
R4820:Fcgbp	UTSW	7	28,113,958 (GRCm38)	missense	probably damaging	1.00
R4863:Fcgbp	UTSW	7	28,086,344 (GRCm38)	missense	probably benign	0.33
R4926:Fcgbp	UTSW	7	28,086,235 (GRCm38)	missense	probably damaging	0.99
R4947:Fcgbp	UTSW	7	28,089,812 (GRCm38)	missense	probably benign	0.00
R4979:Fcgbp	UTSW	7	28,117,570 (GRCm38)	missense	probably benign	0.06
R5002:Fcgbp	UTSW	7	28,086,103 (GRCm38)	splice site	probably null
R5219:Fcgbp	UTSW	7	28,104,085 (GRCm38)	missense	probably damaging	1.00
R5241:Fcgbp	UTSW	7	28,085,199 (GRCm38)	missense	probably damaging	1.00
R5301:Fcgbp	UTSW	7	28,093,674 (GRCm38)	missense	possibly damaging	0.93
R5306:Fcgbp	UTSW	7	28,091,818 (GRCm38)	missense	probably damaging	1.00
R5335:Fcgbp	UTSW	7	28,089,734 (GRCm38)	missense	probably damaging	1.00
R5399:Fcgbp	UTSW	7	28,105,055 (GRCm38)	missense	probably benign	0.05
R5418:Fcgbp	UTSW	7	28,085,313 (GRCm38)	missense	probably damaging	1.00
R5527:Fcgbp	UTSW	7	28,093,635 (GRCm38)	missense	probably benign
R5583:Fcgbp	UTSW	7	28,091,579 (GRCm38)	missense	probably damaging	1.00
R5780:Fcgbp	UTSW	7	28,085,218 (GRCm38)	missense	probably benign	0.02
R5813:Fcgbp	UTSW	7	28,101,494 (GRCm38)	missense	possibly damaging	0.64
R5910:Fcgbp	UTSW	7	28,085,503 (GRCm38)	splice site	probably benign
R5936:Fcgbp	UTSW	7	28,086,692 (GRCm38)	missense	probably damaging	0.98
R5992:Fcgbp	UTSW	7	28,120,534 (GRCm38)	missense	probably benign	0.05
R6091:Fcgbp	UTSW	7	28,104,965 (GRCm38)	missense	possibly damaging	0.90
R6372:Fcgbp	UTSW	7	28,107,008 (GRCm38)	missense	probably damaging	1.00
R6488:Fcgbp	UTSW	7	28,093,538 (GRCm38)	missense	probably damaging	0.96
R6548:Fcgbp	UTSW	7	28,091,918 (GRCm38)	missense	probably benign	0.00
R6553:Fcgbp	UTSW	7	28,113,979 (GRCm38)	missense	possibly damaging	0.79
R6585:Fcgbp	UTSW	7	28,113,979 (GRCm38)	missense	possibly damaging	0.79
R6695:Fcgbp	UTSW	7	28,086,270 (GRCm38)	nonsense	probably null
R6711:Fcgbp	UTSW	7	28,089,673 (GRCm38)	missense	probably damaging	0.99
R6803:Fcgbp	UTSW	7	28,103,212 (GRCm38)	missense	probably benign	0.00
R6822:Fcgbp	UTSW	7	28,107,356 (GRCm38)	missense	probably damaging	1.00
R6907:Fcgbp	UTSW	7	28,085,018 (GRCm38)	missense	probably damaging	1.00
R6912:Fcgbp	UTSW	7	28,089,704 (GRCm38)	missense	probably benign	0.15
R6924:Fcgbp	UTSW	7	28,093,823 (GRCm38)	missense	probably benign
R6943:Fcgbp	UTSW	7	28,092,052 (GRCm38)	missense	probably benign	0.22
R7060:Fcgbp	UTSW	7	28,091,933 (GRCm38)	missense	probably benign	0.20
R7103:Fcgbp	UTSW	7	28,084,962 (GRCm38)	missense	probably benign	0.00
R7208:Fcgbp	UTSW	7	28,104,021 (GRCm38)	missense	probably benign	0.01
R7291:Fcgbp	UTSW	7	28,101,392 (GRCm38)	missense	probably benign	0.00
R7301:Fcgbp	UTSW	7	28,093,436 (GRCm38)	missense	possibly damaging	0.65
R7404:Fcgbp	UTSW	7	28,101,507 (GRCm38)	missense	probably damaging	1.00
R7426:Fcgbp	UTSW	7	28,086,524 (GRCm38)	missense	probably benign	0.00
R7459:Fcgbp	UTSW	7	28,107,285 (GRCm38)	missense	possibly damaging	0.65
R7475:Fcgbp	UTSW	7	28,102,976 (GRCm38)	missense	probably damaging	0.99
R7505:Fcgbp	UTSW	7	28,089,674 (GRCm38)	missense	probably damaging	0.97
R7517:Fcgbp	UTSW	7	28,085,369 (GRCm38)	missense	probably damaging	1.00
R7519:Fcgbp	UTSW	7	28,086,299 (GRCm38)	missense	probably damaging	1.00
R7524:Fcgbp	UTSW	7	28,102,966 (GRCm38)	missense	probably damaging	1.00
R7649:Fcgbp	UTSW	7	28,091,503 (GRCm38)	missense	possibly damaging	0.88
R7782:Fcgbp	UTSW	7	28,085,035 (GRCm38)	nonsense	probably null
R7820:Fcgbp	UTSW	7	28,120,359 (GRCm38)	missense	probably benign	0.01
R7831:Fcgbp	UTSW	7	28,106,979 (GRCm38)	missense	probably damaging	0.98
R7835:Fcgbp	UTSW	7	28,117,207 (GRCm38)	missense	possibly damaging	0.64
R7947:Fcgbp	UTSW	7	28,104,170 (GRCm38)	critical splice donor site	probably null
R8086:Fcgbp	UTSW	7	28,113,964 (GRCm38)	missense	probably damaging	1.00
R8137:Fcgbp	UTSW	7	28,105,071 (GRCm38)	missense	probably damaging	1.00
R8154:Fcgbp	UTSW	7	28,085,082 (GRCm38)	missense	probably benign	0.00
R8169:Fcgbp	UTSW	7	28,085,494 (GRCm38)	critical splice donor site	probably null
R8176:Fcgbp	UTSW	7	28,091,749 (GRCm38)	missense	possibly damaging	0.88
R8193:Fcgbp	UTSW	7	28,104,851 (GRCm38)	missense	probably damaging	1.00
R8313:Fcgbp	UTSW	7	28,086,344 (GRCm38)	missense	probably benign	0.00
R8350:Fcgbp	UTSW	7	28,094,189 (GRCm38)	missense	probably benign	0.02
R8382:Fcgbp	UTSW	7	28,117,337 (GRCm38)	missense	probably benign	0.00
R8393:Fcgbp	UTSW	7	28,107,390 (GRCm38)	missense	probably benign	0.18
R8438:Fcgbp	UTSW	7	28,089,806 (GRCm38)	missense	probably benign	0.25
R8489:Fcgbp	UTSW	7	28,105,010 (GRCm38)	missense	possibly damaging	0.94
R8495:Fcgbp	UTSW	7	28,086,553 (GRCm38)	missense	probably damaging	1.00
R8707:Fcgbp	UTSW	7	28,120,495 (GRCm38)	missense	probably benign	0.01
R8736:Fcgbp	UTSW	7	28,106,196 (GRCm38)	missense	probably benign	0.05
R8816:Fcgbp	UTSW	7	28,084,987 (GRCm38)	missense	probably benign	0.09
R8905:Fcgbp	UTSW	7	28,086,509 (GRCm38)	missense	probably damaging	1.00
R9031:Fcgbp	UTSW	7	28,091,483 (GRCm38)	missense	possibly damaging	0.89
R9063:Fcgbp	UTSW	7	28,091,852 (GRCm38)	missense	probably damaging	1.00
R9180:Fcgbp	UTSW	7	28,103,773 (GRCm38)	nonsense	probably null
R9262:Fcgbp	UTSW	7	28,120,527 (GRCm38)	missense	probably damaging	1.00
R9439:Fcgbp	UTSW	7	28,104,011 (GRCm38)	missense	possibly damaging	0.60
R9526:Fcgbp	UTSW	7	28,091,512 (GRCm38)	missense	probably damaging	1.00
R9603:Fcgbp	UTSW	7	28,103,138 (GRCm38)	missense	probably damaging	1.00
R9635:Fcgbp	UTSW	7	28,101,407 (GRCm38)	missense	probably benign	0.40
R9703:Fcgbp	UTSW	7	28,106,975 (GRCm38)	missense	probably damaging	0.98
R9711:Fcgbp	UTSW	7	28,093,575 (GRCm38)	missense	probably benign	0.00
R9733:Fcgbp	UTSW	7	28,103,587 (GRCm38)	missense	probably damaging	1.00
RF002:Fcgbp	UTSW	7	28,089,755 (GRCm38)	missense	probably benign
X0028:Fcgbp	UTSW	7	28,104,020 (GRCm38)	missense	possibly damaging	0.48
Z1186:Fcgbp	UTSW	7	28,091,647 (GRCm38)	missense	probably benign
Z1186:Fcgbp	UTSW	7	28,089,755 (GRCm38)	missense	probably benign
Z1186:Fcgbp	UTSW	7	28,086,191 (GRCm38)	missense	probably benign
Z1186:Fcgbp	UTSW	7	28,103,884 (GRCm38)	missense	probably benign	0.09
Z1186:Fcgbp	UTSW	7	28,093,345 (GRCm38)	missense	probably benign

Predicted Primers

PCR Primer
(F):5'- GCATCAGGAGACCCTCATTACG -3'
(R):5'- TCAGTGGTGTGTGACAGAAG -3'

Sequencing Primer
(F):5'- GGAGACCCTCATTACGTCACC -3'
(R):5'- TCAGAGCCATGGAACGTTC -3'

Posted On

2017-01-03