Incidental Mutation 'R5718:Ralgapa2'
| ID |
451263 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Ralgapa2
|
| Ensembl Gene |
ENSMUSG00000037110 |
| Gene Name |
Ral GTPase activating protein, alpha subunit 2 (catalytic) |
| Synonyms |
AS250, A230067G21Rik, RGC2 |
| MMRRC Submission |
043338-MU
|
| Accession Numbers |
|
| Essential gene? |
Probably non essential
(E-score: 0.209)
|
| Stock # |
R5718 (G1)
|
| Quality Score |
225 |
|
Status
|
Not validated
|
| Chromosome |
2 |
| Chromosomal Location |
146081799-146354264 bp(-) (GRCm39) |
| Type of Mutation |
splice site (3 bp from exon) |
| DNA Base Change (assembly) |
T to A
at 146295326 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000153734
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000109986]
[ENSMUST00000109986]
[ENSMUST00000109986]
[ENSMUST00000109986]
[ENSMUST00000131824]
[ENSMUST00000131824]
[ENSMUST00000131824]
[ENSMUST00000131824]
[ENSMUST00000228797]
[ENSMUST00000228797]
|
| AlphaFold |
A3KGS3 |
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000109982
|
| Predicted Effect |
probably null
Transcript: ENSMUST00000109986
|
| SMART Domains |
Protein: ENSMUSP00000105613
Gene: ENSMUSG00000037110
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
469 |
480 |
N/A |
INTRINSIC |
|
low complexity region
|
1017 |
1028 |
N/A |
INTRINSIC |
|
low complexity region
|
1296 |
1301 |
N/A |
INTRINSIC |
|
Pfam:Rap_GAP
|
1701 |
1877 |
6.8e-48 |
PFAM |
|
| Predicted Effect |
probably null
Transcript: ENSMUST00000109986
|
| SMART Domains |
Protein: ENSMUSP00000105613
Gene: ENSMUSG00000037110
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
469 |
480 |
N/A |
INTRINSIC |
|
low complexity region
|
1017 |
1028 |
N/A |
INTRINSIC |
|
low complexity region
|
1296 |
1301 |
N/A |
INTRINSIC |
|
Pfam:Rap_GAP
|
1701 |
1877 |
6.8e-48 |
PFAM |
|
| Predicted Effect |
probably null
Transcript: ENSMUST00000109986
|
| SMART Domains |
Protein: ENSMUSP00000105613
Gene: ENSMUSG00000037110
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
469 |
480 |
N/A |
INTRINSIC |
|
low complexity region
|
1017 |
1028 |
N/A |
INTRINSIC |
|
low complexity region
|
1296 |
1301 |
N/A |
INTRINSIC |
|
Pfam:Rap_GAP
|
1701 |
1877 |
6.8e-48 |
PFAM |
|
| Predicted Effect |
probably null
Transcript: ENSMUST00000109986
|
| SMART Domains |
Protein: ENSMUSP00000105613
Gene: ENSMUSG00000037110
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
469 |
480 |
N/A |
INTRINSIC |
|
low complexity region
|
1017 |
1028 |
N/A |
INTRINSIC |
|
low complexity region
|
1296 |
1301 |
N/A |
INTRINSIC |
|
Pfam:Rap_GAP
|
1701 |
1877 |
6.8e-48 |
PFAM |
|
| Predicted Effect |
probably null
Transcript: ENSMUST00000131824
|
| SMART Domains |
Protein: ENSMUSP00000122039
Gene: ENSMUSG00000037110
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
469 |
480 |
N/A |
INTRINSIC |
|
low complexity region
|
979 |
990 |
N/A |
INTRINSIC |
|
low complexity region
|
1258 |
1263 |
N/A |
INTRINSIC |
|
Pfam:Rap_GAP
|
1663 |
1842 |
1.3e-66 |
PFAM |
|
| Predicted Effect |
probably null
Transcript: ENSMUST00000131824
|
| SMART Domains |
Protein: ENSMUSP00000122039
Gene: ENSMUSG00000037110
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
469 |
480 |
N/A |
INTRINSIC |
|
low complexity region
|
979 |
990 |
N/A |
INTRINSIC |
|
low complexity region
|
1258 |
1263 |
N/A |
INTRINSIC |
|
Pfam:Rap_GAP
|
1663 |
1842 |
1.3e-66 |
PFAM |
|
| Predicted Effect |
probably null
Transcript: ENSMUST00000131824
|
| SMART Domains |
Protein: ENSMUSP00000122039
Gene: ENSMUSG00000037110
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
469 |
480 |
N/A |
INTRINSIC |
|
low complexity region
|
979 |
990 |
N/A |
INTRINSIC |
|
low complexity region
|
1258 |
1263 |
N/A |
INTRINSIC |
|
Pfam:Rap_GAP
|
1663 |
1842 |
1.3e-66 |
PFAM |
|
| Predicted Effect |
probably null
Transcript: ENSMUST00000131824
|
| SMART Domains |
Protein: ENSMUSP00000122039
Gene: ENSMUSG00000037110
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
469 |
480 |
N/A |
INTRINSIC |
|
low complexity region
|
979 |
990 |
N/A |
INTRINSIC |
|
low complexity region
|
1258 |
1263 |
N/A |
INTRINSIC |
|
Pfam:Rap_GAP
|
1663 |
1842 |
1.3e-66 |
PFAM |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000135974
|
| Predicted Effect |
probably null
Transcript: ENSMUST00000228797
|
| Predicted Effect |
probably null
Transcript: ENSMUST00000228797
|
| Coding Region Coverage |
- 1x: 99.3%
- 3x: 98.7%
- 10x: 97.4%
- 20x: 95.8%
|
| Validation Efficiency |
|
| MGI Phenotype |
PHENOTYPE: Mice homozygous for a knock-out allele exhibit increased incidence and severity of induced urothelial bladder tumors. [provided by MGI curators]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 66 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Adgra2 |
T |
C |
8: 27,603,514 (GRCm39) |
|
probably null |
Het |
| Ahctf1 |
G |
T |
1: 179,596,904 (GRCm39) |
H81N |
possibly damaging |
Het |
| Alyref2 |
T |
C |
1: 171,331,678 (GRCm39) |
S152P |
possibly damaging |
Het |
| Arhgef7 |
C |
T |
8: 11,835,774 (GRCm39) |
T20I |
probably damaging |
Het |
| Armc3 |
T |
G |
2: 19,308,610 (GRCm39) |
Y759* |
probably null |
Het |
| Atg5 |
A |
G |
10: 44,238,983 (GRCm39) |
S255G |
probably benign |
Het |
| Atp11b |
A |
G |
3: 35,891,665 (GRCm39) |
I1026V |
probably benign |
Het |
| Atp1a2 |
C |
A |
1: 172,107,009 (GRCm39) |
K770N |
probably damaging |
Het |
| Bptf |
G |
T |
11: 107,002,260 (GRCm39) |
A284E |
probably damaging |
Het |
| Celsr2 |
A |
G |
3: 108,300,674 (GRCm39) |
S815P |
probably benign |
Het |
| Chrna5 |
A |
G |
9: 54,905,389 (GRCm39) |
H67R |
probably benign |
Het |
| Cic |
A |
G |
7: 24,972,203 (GRCm39) |
I645V |
probably benign |
Het |
| Clpx |
A |
T |
9: 65,207,246 (GRCm39) |
Q48L |
probably benign |
Het |
| Crhr2 |
G |
A |
6: 55,069,085 (GRCm39) |
Q397* |
probably null |
Het |
| Cyp11a1 |
G |
A |
9: 57,925,508 (GRCm39) |
V48I |
probably benign |
Het |
| Dchs1 |
C |
T |
7: 105,404,955 (GRCm39) |
R2529H |
probably benign |
Het |
| Dnah7c |
A |
T |
1: 46,787,826 (GRCm39) |
H3293L |
possibly damaging |
Het |
| Dock6 |
G |
T |
9: 21,735,789 (GRCm39) |
D986E |
probably benign |
Het |
| Efcab6 |
T |
A |
15: 83,788,439 (GRCm39) |
N952Y |
probably damaging |
Het |
| Eml2 |
G |
A |
7: 18,935,088 (GRCm39) |
V432I |
probably damaging |
Het |
| Epg5 |
G |
A |
18: 78,029,618 (GRCm39) |
C1327Y |
probably damaging |
Het |
| Fbxw18 |
T |
C |
9: 109,520,636 (GRCm39) |
E241G |
probably benign |
Het |
| Fsd1 |
T |
G |
17: 56,297,542 (GRCm39) |
|
probably benign |
Het |
| Gcnt3 |
A |
G |
9: 69,941,552 (GRCm39) |
S339P |
probably benign |
Het |
| Gldc |
T |
A |
19: 30,088,172 (GRCm39) |
K829* |
probably null |
Het |
| Gli3 |
G |
A |
13: 15,652,750 (GRCm39) |
|
probably null |
Het |
| Gm11595 |
G |
A |
11: 99,663,381 (GRCm39) |
R100C |
unknown |
Het |
| Greb1l |
G |
A |
18: 10,542,427 (GRCm39) |
E1341K |
probably damaging |
Het |
| Hmcn1 |
A |
T |
1: 150,566,351 (GRCm39) |
C2217* |
probably null |
Het |
| Hmcn1 |
A |
T |
1: 150,485,417 (GRCm39) |
I4395N |
probably damaging |
Het |
| Hmgxb3 |
A |
G |
18: 61,273,909 (GRCm39) |
M861T |
probably benign |
Het |
| Ift172 |
A |
G |
5: 31,412,621 (GRCm39) |
S1545P |
possibly damaging |
Het |
| Jak3 |
C |
A |
8: 72,136,998 (GRCm39) |
L725M |
probably damaging |
Het |
| Lrig2 |
A |
T |
3: 104,375,931 (GRCm39) |
C90* |
probably null |
Het |
| Mcm7 |
C |
T |
5: 138,163,081 (GRCm39) |
R357H |
possibly damaging |
Het |
| Mcoln2 |
T |
C |
3: 145,887,581 (GRCm39) |
S333P |
probably damaging |
Het |
| Mrpl22 |
A |
T |
11: 58,068,109 (GRCm39) |
I136L |
probably benign |
Het |
| Ncam2 |
A |
T |
16: 81,386,702 (GRCm39) |
|
probably null |
Het |
| Ncdn |
G |
A |
4: 126,643,743 (GRCm39) |
Q360* |
probably null |
Het |
| Nsun2 |
A |
G |
13: 69,771,403 (GRCm39) |
K338E |
probably benign |
Het |
| Obscn |
T |
C |
11: 58,927,634 (GRCm39) |
T6105A |
probably damaging |
Het |
| Or2aj6 |
G |
A |
16: 19,443,139 (GRCm39) |
S237F |
probably benign |
Het |
| Or8g36 |
A |
T |
9: 39,422,338 (GRCm39) |
L226H |
probably damaging |
Het |
| Pcnx4 |
T |
A |
12: 72,613,968 (GRCm39) |
F638I |
possibly damaging |
Het |
| Pfn3 |
T |
C |
13: 55,562,853 (GRCm39) |
I43V |
probably benign |
Het |
| Pigm |
C |
A |
1: 172,205,012 (GRCm39) |
|
probably null |
Het |
| Pkhd1l1 |
T |
A |
15: 44,408,813 (GRCm39) |
S2433R |
probably damaging |
Het |
| Pomt1 |
C |
A |
2: 32,138,704 (GRCm39) |
A440D |
possibly damaging |
Het |
| Ptprj |
T |
C |
2: 90,288,613 (GRCm39) |
D691G |
probably benign |
Het |
| Qrich1 |
T |
A |
9: 108,406,022 (GRCm39) |
S72T |
probably damaging |
Het |
| Rarg |
A |
C |
15: 102,149,502 (GRCm39) |
S156A |
probably damaging |
Het |
| Rasl11a |
A |
G |
5: 146,783,954 (GRCm39) |
K133R |
probably benign |
Het |
| Rcor1 |
A |
G |
12: 111,068,069 (GRCm39) |
D158G |
probably benign |
Het |
| Rpn2 |
C |
T |
2: 157,163,747 (GRCm39) |
T613M |
probably damaging |
Het |
| Sipa1l2 |
T |
A |
8: 126,217,987 (GRCm39) |
H450L |
probably damaging |
Het |
| Slc25a21 |
T |
C |
12: 56,764,941 (GRCm39) |
I263V |
probably benign |
Het |
| Slc25a32 |
A |
T |
15: 38,960,957 (GRCm39) |
V242E |
probably benign |
Het |
| Slc5a5 |
T |
A |
8: 71,340,399 (GRCm39) |
T484S |
probably benign |
Het |
| Tdrd3 |
T |
C |
14: 87,743,876 (GRCm39) |
V608A |
probably benign |
Het |
| Thnsl1 |
C |
A |
2: 21,216,811 (GRCm39) |
H188Q |
possibly damaging |
Het |
| Tshz1 |
A |
T |
18: 84,032,649 (GRCm39) |
H586Q |
probably damaging |
Het |
| Vmn2r27 |
C |
T |
6: 124,169,103 (GRCm39) |
A676T |
possibly damaging |
Het |
| Wasf1 |
G |
A |
10: 40,802,570 (GRCm39) |
R75Q |
probably damaging |
Het |
| Xbp1 |
T |
A |
11: 5,471,903 (GRCm39) |
F10I |
probably benign |
Het |
| Zbtb1 |
G |
A |
12: 76,433,698 (GRCm39) |
M561I |
probably benign |
Het |
| Zfp708 |
T |
C |
13: 67,218,522 (GRCm39) |
K446E |
probably benign |
Het |
|
| Other mutations in Ralgapa2 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00666:Ralgapa2
|
APN |
2 |
146,327,056 (GRCm39) |
missense |
possibly damaging |
0.61 |
|
IGL00915:Ralgapa2
|
APN |
2 |
146,184,442 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01012:Ralgapa2
|
APN |
2 |
146,263,659 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
IGL01018:Ralgapa2
|
APN |
2 |
146,252,112 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL01018:Ralgapa2
|
APN |
2 |
146,252,113 (GRCm39) |
missense |
probably benign |
0.02 |
|
IGL01902:Ralgapa2
|
APN |
2 |
146,156,934 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02160:Ralgapa2
|
APN |
2 |
146,190,360 (GRCm39) |
splice site |
probably benign |
|
|
IGL02321:Ralgapa2
|
APN |
2 |
146,254,736 (GRCm39) |
nonsense |
probably null |
|
|
IGL02412:Ralgapa2
|
APN |
2 |
146,254,052 (GRCm39) |
missense |
probably damaging |
0.96 |
|
IGL03026:Ralgapa2
|
APN |
2 |
146,302,695 (GRCm39) |
splice site |
probably benign |
|
|
IGL03115:Ralgapa2
|
APN |
2 |
146,266,734 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL03256:Ralgapa2
|
APN |
2 |
146,302,632 (GRCm39) |
critical splice donor site |
probably null |
|
|
IGL03379:Ralgapa2
|
APN |
2 |
146,199,907 (GRCm39) |
missense |
probably benign |
0.01 |
|
Chow
|
UTSW |
2 |
146,188,638 (GRCm39) |
nonsense |
probably null |
|
|
purina
|
UTSW |
2 |
146,175,406 (GRCm39) |
missense |
probably damaging |
1.00 |
|
P4748:Ralgapa2
|
UTSW |
2 |
146,188,731 (GRCm39) |
nonsense |
probably null |
|
|
R0012:Ralgapa2
|
UTSW |
2 |
146,254,672 (GRCm39) |
missense |
probably benign |
|
|
R0012:Ralgapa2
|
UTSW |
2 |
146,254,672 (GRCm39) |
missense |
probably benign |
|
|
R0165:Ralgapa2
|
UTSW |
2 |
146,230,407 (GRCm39) |
splice site |
probably benign |
|
|
R0344:Ralgapa2
|
UTSW |
2 |
146,188,714 (GRCm39) |
missense |
possibly damaging |
0.69 |
|
R0402:Ralgapa2
|
UTSW |
2 |
146,276,729 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R0419:Ralgapa2
|
UTSW |
2 |
146,270,592 (GRCm39) |
missense |
possibly damaging |
0.69 |
|
R0638:Ralgapa2
|
UTSW |
2 |
146,184,112 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0704:Ralgapa2
|
UTSW |
2 |
146,293,704 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0722:Ralgapa2
|
UTSW |
2 |
146,230,451 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0866:Ralgapa2
|
UTSW |
2 |
146,277,923 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1065:Ralgapa2
|
UTSW |
2 |
146,292,478 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1212:Ralgapa2
|
UTSW |
2 |
146,199,902 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1395:Ralgapa2
|
UTSW |
2 |
146,230,420 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1614:Ralgapa2
|
UTSW |
2 |
146,230,532 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1686:Ralgapa2
|
UTSW |
2 |
146,199,920 (GRCm39) |
missense |
probably benign |
0.09 |
|
R1799:Ralgapa2
|
UTSW |
2 |
146,184,648 (GRCm39) |
missense |
probably benign |
0.02 |
|
R1905:Ralgapa2
|
UTSW |
2 |
146,229,621 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1956:Ralgapa2
|
UTSW |
2 |
146,302,679 (GRCm39) |
missense |
probably benign |
0.00 |
|
R2144:Ralgapa2
|
UTSW |
2 |
146,230,524 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2148:Ralgapa2
|
UTSW |
2 |
146,273,807 (GRCm39) |
missense |
probably benign |
0.02 |
|
R2219:Ralgapa2
|
UTSW |
2 |
146,263,599 (GRCm39) |
missense |
probably benign |
0.09 |
|
R2220:Ralgapa2
|
UTSW |
2 |
146,263,599 (GRCm39) |
missense |
probably benign |
0.09 |
|
R2261:Ralgapa2
|
UTSW |
2 |
146,184,603 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2402:Ralgapa2
|
UTSW |
2 |
146,195,112 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2495:Ralgapa2
|
UTSW |
2 |
146,203,320 (GRCm39) |
missense |
possibly damaging |
0.82 |
|
R3752:Ralgapa2
|
UTSW |
2 |
146,263,551 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R3953:Ralgapa2
|
UTSW |
2 |
146,277,884 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3956:Ralgapa2
|
UTSW |
2 |
146,277,884 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4177:Ralgapa2
|
UTSW |
2 |
146,327,083 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4182:Ralgapa2
|
UTSW |
2 |
146,277,914 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4193:Ralgapa2
|
UTSW |
2 |
146,184,493 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4332:Ralgapa2
|
UTSW |
2 |
146,102,288 (GRCm39) |
missense |
probably benign |
0.10 |
|
R4507:Ralgapa2
|
UTSW |
2 |
146,195,168 (GRCm39) |
missense |
probably benign |
0.11 |
|
R4574:Ralgapa2
|
UTSW |
2 |
146,277,919 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4585:Ralgapa2
|
UTSW |
2 |
146,156,944 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R4627:Ralgapa2
|
UTSW |
2 |
146,203,373 (GRCm39) |
missense |
possibly damaging |
0.88 |
|
R4647:Ralgapa2
|
UTSW |
2 |
146,229,549 (GRCm39) |
missense |
possibly damaging |
0.69 |
|
R4677:Ralgapa2
|
UTSW |
2 |
146,187,387 (GRCm39) |
missense |
possibly damaging |
0.82 |
|
R4724:Ralgapa2
|
UTSW |
2 |
146,187,453 (GRCm39) |
missense |
possibly damaging |
0.46 |
|
R4760:Ralgapa2
|
UTSW |
2 |
146,188,669 (GRCm39) |
missense |
probably benign |
0.00 |
|
R4831:Ralgapa2
|
UTSW |
2 |
146,246,987 (GRCm39) |
intron |
probably benign |
|
|
R4962:Ralgapa2
|
UTSW |
2 |
146,276,754 (GRCm39) |
nonsense |
probably null |
|
|
R4993:Ralgapa2
|
UTSW |
2 |
146,289,231 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5041:Ralgapa2
|
UTSW |
2 |
146,327,071 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5120:Ralgapa2
|
UTSW |
2 |
146,254,004 (GRCm39) |
missense |
probably benign |
0.26 |
|
R5185:Ralgapa2
|
UTSW |
2 |
146,230,406 (GRCm39) |
splice site |
probably null |
|
|
R5393:Ralgapa2
|
UTSW |
2 |
146,187,375 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5428:Ralgapa2
|
UTSW |
2 |
146,176,414 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R5439:Ralgapa2
|
UTSW |
2 |
146,184,430 (GRCm39) |
missense |
probably benign |
0.08 |
|
R5476:Ralgapa2
|
UTSW |
2 |
146,289,356 (GRCm39) |
missense |
probably benign |
|
|
R5695:Ralgapa2
|
UTSW |
2 |
146,175,397 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5705:Ralgapa2
|
UTSW |
2 |
146,291,193 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5817:Ralgapa2
|
UTSW |
2 |
146,175,406 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5877:Ralgapa2
|
UTSW |
2 |
146,230,489 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5994:Ralgapa2
|
UTSW |
2 |
146,203,373 (GRCm39) |
missense |
probably benign |
0.00 |
|
R6048:Ralgapa2
|
UTSW |
2 |
146,276,765 (GRCm39) |
missense |
possibly damaging |
0.46 |
|
R6158:Ralgapa2
|
UTSW |
2 |
146,266,596 (GRCm39) |
missense |
possibly damaging |
0.69 |
|
R6169:Ralgapa2
|
UTSW |
2 |
146,292,385 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6280:Ralgapa2
|
UTSW |
2 |
146,184,129 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6301:Ralgapa2
|
UTSW |
2 |
146,169,331 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R6650:Ralgapa2
|
UTSW |
2 |
146,230,422 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6959:Ralgapa2
|
UTSW |
2 |
146,184,621 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R7020:Ralgapa2
|
UTSW |
2 |
146,188,638 (GRCm39) |
nonsense |
probably null |
|
|
R7035:Ralgapa2
|
UTSW |
2 |
146,353,777 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7167:Ralgapa2
|
UTSW |
2 |
146,190,374 (GRCm39) |
missense |
probably benign |
|
|
R7186:Ralgapa2
|
UTSW |
2 |
146,230,406 (GRCm39) |
splice site |
probably null |
|
|
R7252:Ralgapa2
|
UTSW |
2 |
146,184,671 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
R7266:Ralgapa2
|
UTSW |
2 |
146,176,488 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7371:Ralgapa2
|
UTSW |
2 |
146,189,046 (GRCm39) |
missense |
probably benign |
0.05 |
|
R7432:Ralgapa2
|
UTSW |
2 |
146,276,776 (GRCm39) |
missense |
probably benign |
0.41 |
|
R7470:Ralgapa2
|
UTSW |
2 |
146,266,587 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7663:Ralgapa2
|
UTSW |
2 |
146,260,335 (GRCm39) |
missense |
probably benign |
0.01 |
|
R7780:Ralgapa2
|
UTSW |
2 |
146,184,334 (GRCm39) |
missense |
probably benign |
0.14 |
|
R7973:Ralgapa2
|
UTSW |
2 |
146,230,481 (GRCm39) |
missense |
possibly damaging |
0.88 |
|
R8018:Ralgapa2
|
UTSW |
2 |
146,182,311 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8063:Ralgapa2
|
UTSW |
2 |
146,285,775 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8070:Ralgapa2
|
UTSW |
2 |
146,195,199 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R8264:Ralgapa2
|
UTSW |
2 |
146,175,370 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
R8309:Ralgapa2
|
UTSW |
2 |
146,246,786 (GRCm39) |
missense |
possibly damaging |
0.66 |
|
R8409:Ralgapa2
|
UTSW |
2 |
146,086,897 (GRCm39) |
missense |
|
|
|
R8474:Ralgapa2
|
UTSW |
2 |
146,266,750 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8487:Ralgapa2
|
UTSW |
2 |
146,230,463 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8492:Ralgapa2
|
UTSW |
2 |
146,184,524 (GRCm39) |
missense |
possibly damaging |
0.50 |
|
R8733:Ralgapa2
|
UTSW |
2 |
146,266,683 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8856:Ralgapa2
|
UTSW |
2 |
146,184,139 (GRCm39) |
missense |
probably benign |
0.30 |
|
R8858:Ralgapa2
|
UTSW |
2 |
146,102,285 (GRCm39) |
critical splice donor site |
probably null |
|
|
R8862:Ralgapa2
|
UTSW |
2 |
146,266,731 (GRCm39) |
missense |
probably benign |
0.41 |
|
R9146:Ralgapa2
|
UTSW |
2 |
146,184,252 (GRCm39) |
missense |
probably benign |
|
|
R9324:Ralgapa2
|
UTSW |
2 |
146,302,645 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9439:Ralgapa2
|
UTSW |
2 |
146,254,058 (GRCm39) |
missense |
probably benign |
|
|
R9457:Ralgapa2
|
UTSW |
2 |
146,176,474 (GRCm39) |
missense |
probably damaging |
0.99 |
|
RF019:Ralgapa2
|
UTSW |
2 |
146,203,423 (GRCm39) |
missense |
possibly damaging |
0.53 |
|
X0019:Ralgapa2
|
UTSW |
2 |
146,230,572 (GRCm39) |
missense |
possibly damaging |
0.56 |
|
Z1088:Ralgapa2
|
UTSW |
2 |
146,276,825 (GRCm39) |
missense |
probably benign |
0.20 |
|
| Predicted Primers |
PCR Primer
(F):5'- CTGGAGGAGTTCTCATGGTC -3'
(R):5'- ACCCACAGTGTTCATGCATAC -3'
Sequencing Primer
(F):5'- GAGGAGTTCTCATGGTCTTTAATCAC -3'
(R):5'- CCACAGTGTTCATGCATACATACATG -3'
|
| Posted On |
2017-01-03 |
Incidental Mutation