Incidental Mutation 'R5735:Tns1'
| ID |
451618 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Tns1
|
| Ensembl Gene |
ENSMUSG00000055322 |
| Gene Name |
tensin 1 |
| Synonyms |
E030018G17Rik, 1110018I21Rik, E030037J05Rik, 1200014E20Rik, Tns |
| MMRRC Submission |
043349-MU
|
| Accession Numbers |
|
| Essential gene? |
Possibly essential
(E-score: 0.565)
|
| Stock # |
R5735 (G1)
|
| Quality Score |
175 |
|
Status
|
Not validated
|
| Chromosome |
1 |
| Chromosomal Location |
73949390-74163608 bp(-) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
T to C
at 73967138 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Threonine to Alanine
at position 1212
(T1212A)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000148638
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000169786]
[ENSMUST00000187584]
[ENSMUST00000187691]
[ENSMUST00000191104]
[ENSMUST00000212888]
|
| AlphaFold |
E9Q0S6 |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000169786
AA Change: T1220A
PolyPhen 2
Score 0.001 (Sensitivity: 0.99; Specificity: 0.15)
|
| SMART Domains |
Protein: ENSMUSP00000127715
Gene: ENSMUSG00000055322
AA Change: T1220A
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
15 |
33 |
N/A |
INTRINSIC |
|
C1
|
62 |
108 |
1.77e-2 |
SMART |
|
low complexity region
|
154 |
167 |
N/A |
INTRINSIC |
|
SCOP:d1d5ra2
|
176 |
348 |
3e-32 |
SMART |
|
PTEN_C2
|
350 |
477 |
1.12e-51 |
SMART |
|
low complexity region
|
822 |
833 |
N/A |
INTRINSIC |
|
low complexity region
|
905 |
922 |
N/A |
INTRINSIC |
|
low complexity region
|
1227 |
1239 |
N/A |
INTRINSIC |
|
low complexity region
|
1284 |
1300 |
N/A |
INTRINSIC |
|
low complexity region
|
1459 |
1470 |
N/A |
INTRINSIC |
|
low complexity region
|
1518 |
1530 |
N/A |
INTRINSIC |
|
SH2
|
1614 |
1716 |
6.85e-17 |
SMART |
|
PTB
|
1747 |
1888 |
1.69e-29 |
SMART |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000185264
|
| Predicted Effect |
unknown
Transcript: ENSMUST00000185331
AA Change: T1037A
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000185529
|
| Predicted Effect |
unknown
Transcript: ENSMUST00000185702
AA Change: T1050A
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000187584
AA Change: T1155A
PolyPhen 2
Score 0.001 (Sensitivity: 0.99; Specificity: 0.15)
|
| SMART Domains |
Protein: ENSMUSP00000140254
Gene: ENSMUSG00000055322
AA Change: T1155A
| Domain | Start | End | E-Value | Type |
|---|
|
C1
|
21 |
67 |
8.6e-5 |
SMART |
|
low complexity region
|
113 |
124 |
N/A |
INTRINSIC |
|
PTPc_DSPc
|
197 |
319 |
9.9e-6 |
SMART |
|
PTEN_C2
|
306 |
433 |
5.6e-56 |
SMART |
|
low complexity region
|
778 |
789 |
N/A |
INTRINSIC |
|
low complexity region
|
861 |
878 |
N/A |
INTRINSIC |
|
low complexity region
|
1162 |
1174 |
N/A |
INTRINSIC |
|
low complexity region
|
1219 |
1235 |
N/A |
INTRINSIC |
|
low complexity region
|
1394 |
1405 |
N/A |
INTRINSIC |
|
low complexity region
|
1453 |
1465 |
N/A |
INTRINSIC |
|
SH2
|
1549 |
1651 |
4.3e-19 |
SMART |
|
PTB
|
1682 |
1823 |
9e-32 |
SMART |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000187691
|
| SMART Domains |
Protein: ENSMUSP00000139844
Gene: ENSMUSG00000055322
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
20 |
36 |
N/A |
INTRINSIC |
|
low complexity region
|
195 |
206 |
N/A |
INTRINSIC |
|
low complexity region
|
254 |
266 |
N/A |
INTRINSIC |
|
SH2
|
350 |
452 |
4.3e-19 |
SMART |
|
PTB
|
483 |
624 |
9e-32 |
SMART |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000191104
AA Change: T1199A
PolyPhen 2
Score 0.001 (Sensitivity: 0.99; Specificity: 0.15)
|
| SMART Domains |
Protein: ENSMUSP00000140317
Gene: ENSMUSG00000055322
AA Change: T1199A
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
15 |
33 |
N/A |
INTRINSIC |
|
C1
|
62 |
108 |
8.6e-5 |
SMART |
|
low complexity region
|
154 |
167 |
N/A |
INTRINSIC |
|
PTPc_DSPc
|
241 |
363 |
9.9e-6 |
SMART |
|
PTEN_C2
|
350 |
477 |
5.6e-56 |
SMART |
|
low complexity region
|
822 |
833 |
N/A |
INTRINSIC |
|
low complexity region
|
905 |
922 |
N/A |
INTRINSIC |
|
low complexity region
|
1206 |
1218 |
N/A |
INTRINSIC |
|
low complexity region
|
1263 |
1279 |
N/A |
INTRINSIC |
|
low complexity region
|
1438 |
1449 |
N/A |
INTRINSIC |
|
low complexity region
|
1497 |
1509 |
N/A |
INTRINSIC |
|
SH2
|
1593 |
1695 |
4.3e-19 |
SMART |
|
PTB
|
1726 |
1867 |
9e-32 |
SMART |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000191527
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000212888
AA Change: T1212A
PolyPhen 2
Score 0.003 (Sensitivity: 0.98; Specificity: 0.44)
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000189228
|
| Coding Region Coverage |
- 1x: 99.0%
- 3x: 98.3%
- 10x: 96.8%
- 20x: 94.4%
|
| Validation Efficiency |
|
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] The protein encoded by this gene localizes to focal adhesions, regions of the plasma membrane where the cell attaches to the extracellular matrix. This protein crosslinks actin filaments and contains a Src homology 2 (SH2) domain, which is often found in molecules involved in signal transduction. This protein is a substrate of calpain II. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Apr 2015]
PHENOTYPE: Mice homozygous for a knock-out allele exhibit reduced female fertility, and develop kidney cysts and progressive kidney degeneration that may lead to death from renal failure. [provided by MGI curators]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 67 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Adamts16 |
C |
A |
13: 70,984,337 (GRCm39) |
D109Y |
possibly damaging |
Het |
| Armc8 |
T |
A |
9: 99,379,447 (GRCm39) |
|
probably null |
Het |
| Atg4b |
G |
T |
1: 93,701,519 (GRCm39) |
G71V |
probably damaging |
Het |
| Atp10b |
A |
T |
11: 43,042,601 (GRCm39) |
M54L |
probably benign |
Het |
| Baiap2l1 |
A |
G |
5: 144,223,112 (GRCm39) |
L75P |
probably damaging |
Het |
| Bnc2 |
A |
C |
4: 84,210,908 (GRCm39) |
L487R |
probably damaging |
Het |
| Cacng7 |
T |
C |
7: 3,387,539 (GRCm39) |
S141P |
probably benign |
Het |
| Carmil2 |
G |
A |
8: 106,424,663 (GRCm39) |
G1361D |
probably damaging |
Het |
| Cenpf |
T |
C |
1: 189,386,560 (GRCm39) |
I1907V |
probably benign |
Het |
| Cep192 |
T |
C |
18: 68,013,866 (GRCm39) |
V2422A |
probably benign |
Het |
| Cfap73 |
T |
A |
5: 120,770,671 (GRCm39) |
Q33L |
probably benign |
Het |
| Cip2a |
T |
A |
16: 48,837,856 (GRCm39) |
|
probably null |
Het |
| Cmtm2a |
A |
T |
8: 105,019,418 (GRCm39) |
I57N |
probably damaging |
Het |
| Col6a2 |
T |
A |
10: 76,435,727 (GRCm39) |
D836V |
probably benign |
Het |
| Dnah2 |
A |
G |
11: 69,321,643 (GRCm39) |
V3839A |
possibly damaging |
Het |
| Enpp1 |
A |
T |
10: 24,530,817 (GRCm39) |
F546L |
possibly damaging |
Het |
| Eps8l2 |
A |
G |
7: 140,940,290 (GRCm39) |
T507A |
probably damaging |
Het |
| Erg28 |
C |
T |
12: 85,862,926 (GRCm39) |
E129K |
probably benign |
Het |
| Erlec1 |
A |
T |
11: 30,900,591 (GRCm39) |
N153K |
probably benign |
Het |
| Fam234a |
T |
C |
17: 26,432,679 (GRCm39) |
E490G |
probably damaging |
Het |
| Fat4 |
C |
T |
3: 39,003,725 (GRCm39) |
R1815C |
probably damaging |
Het |
| Galnt1 |
T |
G |
18: 24,397,577 (GRCm39) |
I226S |
possibly damaging |
Het |
| Ifnl2 |
T |
A |
7: 28,209,614 (GRCm39) |
I58F |
possibly damaging |
Het |
| Itih5 |
A |
G |
2: 10,245,572 (GRCm39) |
N554D |
probably benign |
Het |
| Kcna10 |
A |
G |
3: 107,102,394 (GRCm39) |
I342V |
probably benign |
Het |
| Kif6 |
G |
A |
17: 50,139,210 (GRCm39) |
E561K |
probably damaging |
Het |
| Kl |
A |
G |
5: 150,915,003 (GRCm39) |
N910S |
possibly damaging |
Het |
| Lpar2 |
G |
T |
8: 70,276,385 (GRCm39) |
R58L |
probably damaging |
Het |
| Macrod2 |
A |
G |
2: 140,260,809 (GRCm39) |
T27A |
possibly damaging |
Het |
| Mfsd2a |
A |
T |
4: 122,843,120 (GRCm39) |
V387D |
probably damaging |
Het |
| Npas3 |
A |
T |
12: 54,050,262 (GRCm39) |
T231S |
probably benign |
Het |
| Or4a70 |
A |
T |
2: 89,323,812 (GRCm39) |
N281K |
probably damaging |
Het |
| Or52n5 |
A |
T |
7: 104,587,966 (GRCm39) |
T78S |
probably benign |
Het |
| Or5aq1b |
A |
T |
2: 86,901,756 (GRCm39) |
C241S |
probably damaging |
Het |
| Or8h10 |
A |
G |
2: 86,809,044 (GRCm39) |
V32A |
probably benign |
Het |
| Otx1 |
C |
A |
11: 21,947,037 (GRCm39) |
A91S |
probably damaging |
Het |
| Pde10a |
A |
T |
17: 9,160,024 (GRCm39) |
I432F |
probably damaging |
Het |
| Phka2 |
ACC |
AC |
X: 159,342,862 (GRCm39) |
|
probably null |
Het |
| Pomt1 |
G |
A |
2: 32,133,517 (GRCm39) |
G218R |
probably damaging |
Het |
| Potefam1 |
A |
T |
2: 111,055,837 (GRCm39) |
L183* |
probably null |
Het |
| Pramel22 |
A |
T |
4: 143,381,205 (GRCm39) |
C273S |
probably damaging |
Het |
| Prdm5 |
C |
T |
6: 65,904,974 (GRCm39) |
T157I |
possibly damaging |
Het |
| Psen2 |
T |
A |
1: 180,068,491 (GRCm39) |
E54V |
probably benign |
Het |
| Ptpn13 |
C |
A |
5: 103,702,686 (GRCm39) |
H1217Q |
probably benign |
Het |
| Ptprt |
A |
G |
2: 161,376,484 (GRCm39) |
S1306P |
probably damaging |
Het |
| Ptpru |
G |
T |
4: 131,565,401 (GRCm39) |
P23T |
probably benign |
Het |
| Rtn3 |
T |
C |
19: 7,434,057 (GRCm39) |
E626G |
probably damaging |
Het |
| Scn3a |
A |
T |
2: 65,312,622 (GRCm39) |
M1191K |
probably damaging |
Het |
| Scn3a |
T |
A |
2: 65,314,803 (GRCm39) |
N1086I |
probably benign |
Het |
| Sgms2 |
A |
T |
3: 131,129,866 (GRCm39) |
M174K |
probably damaging |
Het |
| Skor1 |
T |
A |
9: 63,053,346 (GRCm39) |
I180F |
probably damaging |
Het |
| Slit2 |
T |
G |
5: 48,416,958 (GRCm39) |
C1003W |
probably damaging |
Het |
| Tbc1d2b |
T |
A |
9: 90,104,462 (GRCm39) |
Q560L |
possibly damaging |
Het |
| Themis |
A |
G |
10: 28,598,530 (GRCm39) |
I51V |
probably benign |
Het |
| Tmem203 |
T |
C |
2: 25,146,085 (GRCm39) |
V135A |
probably benign |
Het |
| Trgv5 |
T |
G |
13: 19,376,695 (GRCm39) |
H47Q |
probably benign |
Het |
| Trim2 |
G |
A |
3: 84,075,029 (GRCm39) |
A697V |
probably damaging |
Het |
| Ubxn4 |
T |
C |
1: 128,186,677 (GRCm39) |
S37P |
possibly damaging |
Het |
| Vmn2r17 |
A |
G |
5: 109,600,716 (GRCm39) |
I671M |
possibly damaging |
Het |
| Vmn2r94 |
G |
T |
17: 18,464,066 (GRCm39) |
S741R |
probably damaging |
Het |
| Vwce |
C |
A |
19: 10,624,431 (GRCm39) |
D414E |
probably benign |
Het |
| Zfp397 |
T |
C |
18: 24,093,249 (GRCm39) |
S245P |
possibly damaging |
Het |
| Zfp747l1 |
G |
T |
7: 126,984,579 (GRCm39) |
H174Q |
possibly damaging |
Het |
| Zfp809 |
T |
A |
9: 22,150,227 (GRCm39) |
Y241* |
probably null |
Het |
| Zfp995 |
C |
T |
17: 22,101,010 (GRCm39) |
C29Y |
probably benign |
Het |
| Zfta |
A |
G |
19: 7,400,161 (GRCm39) |
E209G |
probably benign |
Het |
| Zfyve26 |
T |
C |
12: 79,320,147 (GRCm39) |
D1066G |
probably damaging |
Het |
|
| Other mutations in Tns1 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00954:Tns1
|
APN |
1 |
73,964,128 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL01288:Tns1
|
APN |
1 |
73,992,969 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01536:Tns1
|
APN |
1 |
73,958,807 (GRCm39) |
splice site |
probably benign |
|
|
IGL01568:Tns1
|
APN |
1 |
73,992,668 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01683:Tns1
|
APN |
1 |
73,992,428 (GRCm39) |
missense |
probably damaging |
0.98 |
|
IGL02267:Tns1
|
APN |
1 |
74,031,290 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
IGL02597:Tns1
|
APN |
1 |
74,025,032 (GRCm39) |
critical splice donor site |
probably null |
|
|
IGL02819:Tns1
|
APN |
1 |
73,976,407 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL03370:Tns1
|
APN |
1 |
74,025,053 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0087:Tns1
|
UTSW |
1 |
73,956,076 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R0207:Tns1
|
UTSW |
1 |
73,976,477 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
R0411:Tns1
|
UTSW |
1 |
73,964,920 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R0543:Tns1
|
UTSW |
1 |
73,991,856 (GRCm39) |
missense |
probably benign |
0.01 |
|
R0552:Tns1
|
UTSW |
1 |
73,959,722 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0720:Tns1
|
UTSW |
1 |
73,964,740 (GRCm39) |
missense |
probably benign |
0.03 |
|
R0828:Tns1
|
UTSW |
1 |
73,958,825 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1034:Tns1
|
UTSW |
1 |
73,981,128 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1061:Tns1
|
UTSW |
1 |
73,956,831 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1819:Tns1
|
UTSW |
1 |
73,955,635 (GRCm39) |
splice site |
probably benign |
|
|
R1826:Tns1
|
UTSW |
1 |
73,992,793 (GRCm39) |
start codon destroyed |
probably null |
0.91 |
|
R2208:Tns1
|
UTSW |
1 |
74,118,399 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3723:Tns1
|
UTSW |
1 |
73,964,099 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R4079:Tns1
|
UTSW |
1 |
74,034,467 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4111:Tns1
|
UTSW |
1 |
73,981,091 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4155:Tns1
|
UTSW |
1 |
73,953,790 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4156:Tns1
|
UTSW |
1 |
73,953,790 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4157:Tns1
|
UTSW |
1 |
73,953,790 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4274:Tns1
|
UTSW |
1 |
73,967,257 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4426:Tns1
|
UTSW |
1 |
74,024,908 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R4649:Tns1
|
UTSW |
1 |
73,992,930 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4742:Tns1
|
UTSW |
1 |
74,163,449 (GRCm39) |
critical splice donor site |
probably null |
|
|
R4869:Tns1
|
UTSW |
1 |
73,991,774 (GRCm39) |
missense |
probably benign |
|
|
R4961:Tns1
|
UTSW |
1 |
73,975,074 (GRCm39) |
missense |
probably benign |
0.35 |
|
R5025:Tns1
|
UTSW |
1 |
73,964,641 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5035:Tns1
|
UTSW |
1 |
73,992,979 (GRCm39) |
start gained |
probably benign |
|
|
R5062:Tns1
|
UTSW |
1 |
73,992,023 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5080:Tns1
|
UTSW |
1 |
73,992,099 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5213:Tns1
|
UTSW |
1 |
73,992,771 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5256:Tns1
|
UTSW |
1 |
74,034,585 (GRCm39) |
intron |
probably benign |
|
|
R5368:Tns1
|
UTSW |
1 |
73,980,176 (GRCm39) |
missense |
probably benign |
0.07 |
|
R5391:Tns1
|
UTSW |
1 |
74,029,568 (GRCm39) |
splice site |
probably null |
|
|
R5587:Tns1
|
UTSW |
1 |
73,959,755 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R5855:Tns1
|
UTSW |
1 |
73,957,192 (GRCm39) |
missense |
possibly damaging |
0.83 |
|
R5999:Tns1
|
UTSW |
1 |
73,967,256 (GRCm39) |
nonsense |
probably null |
|
|
R6122:Tns1
|
UTSW |
1 |
73,991,578 (GRCm39) |
critical splice donor site |
probably null |
|
|
R6148:Tns1
|
UTSW |
1 |
73,992,612 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6457:Tns1
|
UTSW |
1 |
73,957,209 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R6525:Tns1
|
UTSW |
1 |
73,992,629 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6712:Tns1
|
UTSW |
1 |
74,118,460 (GRCm39) |
nonsense |
probably null |
|
|
R6773:Tns1
|
UTSW |
1 |
73,958,866 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6825:Tns1
|
UTSW |
1 |
74,041,482 (GRCm39) |
nonsense |
probably null |
|
|
R7085:Tns1
|
UTSW |
1 |
73,964,621 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7128:Tns1
|
UTSW |
1 |
74,034,463 (GRCm39) |
missense |
|
|
|
R7209:Tns1
|
UTSW |
1 |
73,993,074 (GRCm39) |
missense |
possibly damaging |
0.68 |
|
R7348:Tns1
|
UTSW |
1 |
73,956,076 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R7570:Tns1
|
UTSW |
1 |
73,992,638 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7670:Tns1
|
UTSW |
1 |
73,991,636 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R7769:Tns1
|
UTSW |
1 |
73,992,530 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7833:Tns1
|
UTSW |
1 |
74,130,490 (GRCm39) |
intron |
probably benign |
|
|
R8052:Tns1
|
UTSW |
1 |
73,992,596 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8225:Tns1
|
UTSW |
1 |
74,025,046 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8244:Tns1
|
UTSW |
1 |
73,976,410 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8321:Tns1
|
UTSW |
1 |
74,024,939 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
R8344:Tns1
|
UTSW |
1 |
74,024,201 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8378:Tns1
|
UTSW |
1 |
73,976,405 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8434:Tns1
|
UTSW |
1 |
73,964,765 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8773:Tns1
|
UTSW |
1 |
73,976,407 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R9211:Tns1
|
UTSW |
1 |
73,956,948 (GRCm39) |
missense |
possibly damaging |
0.63 |
|
R9251:Tns1
|
UTSW |
1 |
74,030,855 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9315:Tns1
|
UTSW |
1 |
73,980,141 (GRCm39) |
missense |
|
|
|
R9411:Tns1
|
UTSW |
1 |
73,992,662 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9592:Tns1
|
UTSW |
1 |
74,029,553 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9658:Tns1
|
UTSW |
1 |
73,981,183 (GRCm39) |
missense |
probably benign |
0.08 |
|
R9658:Tns1
|
UTSW |
1 |
73,981,182 (GRCm39) |
missense |
probably benign |
0.14 |
|
Z1177:Tns1
|
UTSW |
1 |
74,041,466 (GRCm39) |
missense |
probably benign |
0.12 |
|
| Predicted Primers |
PCR Primer
(F):5'- TCTTAAGACTGCAGCAGAAAGC -3'
(R):5'- GGACTCCTACCACATCTATGC -3'
Sequencing Primer
(F):5'- CTATCCAAAGCTTTGAGGAAGGC -3'
(R):5'- GACTCCTACCACATCTATGCTCATTC -3'
|
| Posted On |
2017-01-03 |
Incidental Mutation