Mutagenetix > Incidental Mutation

Incidental Mutation 'R5707:Tenm2'

452035

Institutional Source

Beutler Lab

Gene Symbol

Tenm2

Ensembl Gene

ENSMUSG00000049336

Gene Name

teneurin transmembrane protein 2

Synonyms

2610040L17Rik, 9330187F13Rik, D3Bwg1534e, Ten-m2, Odz2

MMRRC Submission

043332-MU

Accession Numbers

Essential gene?

Possibly essential (E-score: 0.514) question?

Stock #

R5707 (G1)

Quality Score

225

Status

Validated

Chromosome

Chromosomal Location

36006656-37235964 bp(-) (GRCm38)

Type of Mutation

missense

DNA Base Change (assembly)

T to C at 36047182 bp (GRCm38)

Zygosity

Heterozygous

Amino Acid Change

Isoleucine to Valine at position 1556 (I1556V)

Ref Sequence

ENSEMBL: ENSMUSP00000052014 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000057207] [ENSMUST00000102801] [ENSMUST00000163524]

AlphaFold

no structure available at present

Predicted Effect

possibly damaging
Transcript: ENSMUST00000057207
AA Change: I1556V

PolyPhen 2 Score 0.785 (Sensitivity: 0.85; Specificity: 0.93)

SMART Domains

Protein: ENSMUSP00000052014
Gene: ENSMUSG00000049336
AA Change: I1556V

Domain	Start	End	E-Value	Type
Pfam:Ten_N	10	374	4.9e-177	PFAM
transmembrane domain	375	397	N/A	INTRINSIC
EGF	575	603	5.62e0	SMART
EGF_like	606	634	4.93e1	SMART
EGF	639	668	1.76e1	SMART
EGF	671	700	1.43e-1	SMART
EGF	705	735	1.2e1	SMART
EGF	738	766	9.63e0	SMART
EGF	769	797	1.25e1	SMART
EGF	800	832	1.4e0	SMART
low complexity region	1459	1475	N/A	INTRINSIC
low complexity region	2219	2230	N/A	INTRINSIC
Pfam:Tox-GHH	2681	2758	1.4e-34	PFAM

Predicted Effect

possibly damaging
Transcript: ENSMUST00000102801
AA Change: I1555V

PolyPhen 2 Score 0.655 (Sensitivity: 0.87; Specificity: 0.91)

SMART Domains

Protein: ENSMUSP00000099865
Gene: ENSMUSG00000049336
AA Change: I1555V

Domain	Start	End	E-Value	Type
Pfam:Ten_N	9	374	2e-186	PFAM
transmembrane domain	375	397	N/A	INTRINSIC
EGF	575	603	5.62e0	SMART
EGF_like	606	634	4.93e1	SMART
EGF	639	668	1.76e1	SMART
EGF	671	700	1.43e-1	SMART
EGF	705	735	1.2e1	SMART
EGF	737	765	9.63e0	SMART
EGF	768	796	1.25e1	SMART
EGF	799	831	1.4e0	SMART
low complexity region	1458	1474	N/A	INTRINSIC
low complexity region	2218	2229	N/A	INTRINSIC
Pfam:Tox-GHH	2679	2757	2e-34	PFAM

Predicted Effect

possibly damaging
Transcript: ENSMUST00000163524
AA Change: I1555V

PolyPhen 2 Score 0.655 (Sensitivity: 0.87; Specificity: 0.91)

SMART Domains

Protein: ENSMUSP00000129951
Gene: ENSMUSG00000049336
AA Change: I1555V

Domain	Start	End	E-Value	Type
Pfam:Ten_N	9	374	2e-186	PFAM
transmembrane domain	375	397	N/A	INTRINSIC
EGF	575	603	5.62e0	SMART
EGF_like	606	634	4.93e1	SMART
EGF	639	668	1.76e1	SMART
EGF	671	700	1.43e-1	SMART
EGF	705	735	1.2e1	SMART
EGF	737	765	9.63e0	SMART
EGF	768	796	1.25e1	SMART
EGF	799	831	1.4e0	SMART
low complexity region	1458	1474	N/A	INTRINSIC
low complexity region	2218	2229	N/A	INTRINSIC
Pfam:Tox-GHH	2679	2757	2e-34	PFAM

Meta Mutation Damage Score

0.1122

Coding Region Coverage

1x: 99.2%
3x: 98.6%
10x: 97.3%
20x: 95.4%

Validation Efficiency

97% (56/58)

MGI Phenotype

PHENOTYPE: Mice homozygous for a null allele show abnormalities in the laterality and mapping of ipsilateral retinal projections that lead to loss of ipsilateral drive, defects in binocular vision, and impaired performance on a visual discrimination task. [provided by MGI curators]

Allele List at MGI

Other mutations in this stock

Total: 57 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
Abca13	T	C	11: 9,510,620 (GRCm38)	L4210P	probably damaging	Het
Adcy6	T	C	15: 98,598,741 (GRCm38)	T518A	probably damaging	Het
Adgb	C	T	10: 10,391,757 (GRCm38)	V940I	probably damaging	Het
Aqp11	A	G	7: 97,737,428 (GRCm38)	V187A	possibly damaging	Het
Arhgef15	A	G	11: 68,954,715 (GRCm38)	S104P	probably damaging	Het
Birc6	T	A	17: 74,696,404 (GRCm38)	N4762K	probably damaging	Het
Cacna1e	T	C	1: 154,633,717 (GRCm38)	D264G	probably damaging	Het
Cela3b	G	T	4: 137,424,856 (GRCm38)	Q97K	probably damaging	Het
Cenpc1	T	A	5: 86,035,434 (GRCm38)	R499W	possibly damaging	Het
Chct1	A	G	11: 85,173,312 (GRCm38)	N93S	probably benign	Het
Cnr1	C	A	4: 33,944,330 (GRCm38)	C239*	probably null	Het
Col6a2	T	C	10: 76,611,031 (GRCm38)	K348E	possibly damaging	Het
Ctnnb1	C	A	9: 120,955,168 (GRCm38)	L368I	probably benign	Het
Diras1	T	C	10: 81,022,081 (GRCm38)	E112G	probably benign	Het
Dop1a	T	A	9: 86,502,997 (GRCm38)	M332K	possibly damaging	Het
Dpy19l1	T	C	9: 24,414,267 (GRCm38)	*747W	probably null	Het
Dydc2	T	G	14: 41,061,954 (GRCm38)	T71P	probably damaging	Het
Elapor2	A	G	5: 9,441,698 (GRCm38)	Y686C	probably damaging	Het
Ggt1	T	A	10: 75,585,238 (GRCm38)	I429N	probably benign	Het
Gm5114	G	C	7: 39,411,276 (GRCm38)	L50V	probably benign	Het
Gm5121	T	G	9: 57,334,483 (GRCm38)		noncoding transcript	Het
Kidins220	A	G	12: 25,013,391 (GRCm38)	D933G	probably damaging	Het
Kirrel3	A	G	9: 35,013,276 (GRCm38)	K286R	probably damaging	Het
Klf5	T	C	14: 99,301,508 (GRCm38)	I39T	probably benign	Het
Krt14	C	T	11: 100,204,758 (GRCm38)	V274I	possibly damaging	Het
Meiob	A	G	17: 24,835,051 (GRCm38)	D364G	probably benign	Het
Mroh7	T	A	4: 106,681,885 (GRCm38)	E1190D	possibly damaging	Het
Mtmr7	T	C	8: 40,558,162 (GRCm38)	E285G	possibly damaging	Het
Nhsl1	C	T	10: 18,526,503 (GRCm38)	T1159M	probably damaging	Het
Odad4	G	A	11: 100,554,061 (GRCm38)	A348T	probably damaging	Het
Or1af1	C	A	2: 37,219,889 (GRCm38)	N133K	probably benign	Het
Or1e23	G	T	11: 73,516,625 (GRCm38)	D191E	probably damaging	Het
Or2b2b	A	G	13: 21,674,599 (GRCm38)	L115P	probably damaging	Het
Pcare	G	T	17: 71,751,572 (GRCm38)	A370E	possibly damaging	Het
Pdlim5	T	A	3: 142,304,299 (GRCm38)	H294L	probably damaging	Het
Pdzd8	A	T	19: 59,299,625 (GRCm38)	D1114E	probably benign	Het
Phf20	T	G	2: 156,296,771 (GRCm38)		probably null	Het
Plec	C	T	15: 76,199,671 (GRCm38)		probably benign	Het
Ppp1r18	T	C	17: 35,867,236 (GRCm38)	M1T	probably null	Het
Ppp4r3a	G	A	12: 101,058,511 (GRCm38)	T243I	probably damaging	Het
Prss41	C	T	17: 23,842,416 (GRCm38)	V134I	probably benign	Het
Pter	T	C	2: 12,978,180 (GRCm38)		probably benign	Het
Rasgef1b	T	G	5: 99,234,602 (GRCm38)	K176N	possibly damaging	Het
Reps1	T	A	10: 18,056,010 (GRCm38)	D16E	probably benign	Het
Slc4a5	T	A	6: 83,261,415 (GRCm38)	D73E	probably benign	Het
Smgc	A	T	15: 91,860,663 (GRCm38)	T146S	possibly damaging	Het
Sptbn1	A	T	11: 30,143,174 (GRCm38)	W396R	possibly damaging	Het
Stkld1	A	G	2: 26,943,987 (GRCm38)	E162G	probably damaging	Het
Tanc1	T	C	2: 59,758,530 (GRCm38)	F106L	probably benign	Het
Tarbp1	A	G	8: 126,467,144 (GRCm38)	Y340H	probably damaging	Het
Tmem64	T	C	4: 15,266,288 (GRCm38)	C113R	probably damaging	Het
Try4	T	C	6: 41,305,043 (GRCm38)	F188L	possibly damaging	Het
Ucn3	A	G	13: 3,941,556 (GRCm38)	V32A	probably benign	Het
Vmn2r83	T	A	10: 79,491,349 (GRCm38)	M597K	possibly damaging	Het
Wdr90	A	G	17: 25,857,192 (GRCm38)	V491A	probably benign	Het
Xylt1	T	A	7: 117,656,494 (GRCm38)	M763K	possibly damaging	Het
Zfp507	G	T	7: 35,794,163 (GRCm38)	A485E	probably damaging	Het

Other mutations in Tenm2

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00161:Tenm2	APN	11	36,206,899 (GRCm38)	splice site	probably benign
IGL00834:Tenm2	APN	11	36,024,258 (GRCm38)	missense	probably damaging	1.00
IGL00911:Tenm2	APN	11	36,008,733 (GRCm38)	nonsense	probably null
IGL00937:Tenm2	APN	11	36,024,623 (GRCm38)	missense	probably damaging	1.00
IGL01154:Tenm2	APN	11	36,041,544 (GRCm38)	missense	probably damaging	1.00
IGL01313:Tenm2	APN	11	36,024,248 (GRCm38)	missense	probably damaging	0.98
IGL01346:Tenm2	APN	11	36,027,405 (GRCm38)	nonsense	probably null
IGL01539:Tenm2	APN	11	36,106,827 (GRCm38)	missense	possibly damaging	0.89
IGL01629:Tenm2	APN	11	36,864,884 (GRCm38)	missense	probably damaging	0.98
IGL01780:Tenm2	APN	11	36,046,941 (GRCm38)	missense	probably benign
IGL01821:Tenm2	APN	11	36,023,883 (GRCm38)	missense	probably damaging	0.98
IGL01988:Tenm2	APN	11	36,027,251 (GRCm38)	missense	probably damaging	1.00
IGL02002:Tenm2	APN	11	36,207,095 (GRCm38)	missense	probably benign
IGL02449:Tenm2	APN	11	36,023,622 (GRCm38)	missense	probably damaging	0.99
IGL02505:Tenm2	APN	11	36,051,916 (GRCm38)	nonsense	probably null
IGL02649:Tenm2	APN	11	36,207,085 (GRCm38)	missense	possibly damaging	0.85
IGL02688:Tenm2	APN	11	36,068,458 (GRCm38)	missense	probably benign	0.05
IGL02801:Tenm2	APN	11	36,047,030 (GRCm38)	nonsense	probably null
IGL02928:Tenm2	APN	11	36,027,170 (GRCm38)	missense	possibly damaging	0.69
IGL02940:Tenm2	APN	11	36,041,644 (GRCm38)	missense	probably damaging	1.00
IGL03202:Tenm2	APN	11	36,024,548 (GRCm38)	missense	probably damaging	1.00
IGL03213:Tenm2	APN	11	36,023,330 (GRCm38)	missense	probably benign	0.05
IGL03276:Tenm2	APN	11	36,072,776 (GRCm38)	missense	possibly damaging	0.95
IGL03296:Tenm2	APN	11	36,052,025 (GRCm38)	splice site	probably null
IGL03381:Tenm2	APN	11	36,068,411 (GRCm38)	missense	probably benign	0.01
IGL03398:Tenm2	APN	11	36,024,543 (GRCm38)	missense	probably damaging	1.00
browser	UTSW	11	36,046,765 (GRCm38)	critical splice donor site	probably null
mosaic	UTSW	11	36,063,775 (GRCm38)	critical splice donor site	probably null
IGL02799:Tenm2	UTSW	11	36,273,408 (GRCm38)	missense	probably damaging	1.00
PIT4260001:Tenm2	UTSW	11	36,163,730 (GRCm38)	missense	probably damaging	1.00
PIT4382001:Tenm2	UTSW	11	36,063,902 (GRCm38)	missense	probably damaging	0.99
R0004:Tenm2	UTSW	11	36,023,357 (GRCm38)	missense	probably damaging	1.00
R0420:Tenm2	UTSW	11	36,207,124 (GRCm38)	splice site	probably benign
R0537:Tenm2	UTSW	11	36,163,730 (GRCm38)	missense	probably damaging	1.00
R0599:Tenm2	UTSW	11	36,024,780 (GRCm38)	missense	possibly damaging	0.93
R0636:Tenm2	UTSW	11	36,943,976 (GRCm38)	missense	probably damaging	1.00
R0693:Tenm2	UTSW	11	36,024,809 (GRCm38)	missense	probably damaging	1.00
R0991:Tenm2	UTSW	11	36,063,177 (GRCm38)	missense	possibly damaging	0.94
R0992:Tenm2	UTSW	11	36,063,177 (GRCm38)	missense	possibly damaging	0.94
R1167:Tenm2	UTSW	11	36,864,684 (GRCm38)	missense	probably benign	0.30
R1177:Tenm2	UTSW	11	36,063,177 (GRCm38)	missense	possibly damaging	0.94
R1178:Tenm2	UTSW	11	36,063,177 (GRCm38)	missense	possibly damaging	0.94
R1179:Tenm2	UTSW	11	36,063,177 (GRCm38)	missense	possibly damaging	0.94
R1180:Tenm2	UTSW	11	36,063,177 (GRCm38)	missense	possibly damaging	0.94
R1181:Tenm2	UTSW	11	36,063,177 (GRCm38)	missense	possibly damaging	0.94
R1193:Tenm2	UTSW	11	36,063,177 (GRCm38)	missense	possibly damaging	0.94
R1194:Tenm2	UTSW	11	36,063,177 (GRCm38)	missense	possibly damaging	0.94
R1195:Tenm2	UTSW	11	36,063,177 (GRCm38)	missense	possibly damaging	0.94
R1195:Tenm2	UTSW	11	36,063,177 (GRCm38)	missense	possibly damaging	0.94
R1195:Tenm2	UTSW	11	36,063,177 (GRCm38)	missense	possibly damaging	0.94
R1259:Tenm2	UTSW	11	36,063,177 (GRCm38)	missense	possibly damaging	0.94
R1265:Tenm2	UTSW	11	36,063,177 (GRCm38)	missense	possibly damaging	0.94
R1267:Tenm2	UTSW	11	36,063,177 (GRCm38)	missense	possibly damaging	0.94
R1268:Tenm2	UTSW	11	36,063,177 (GRCm38)	missense	possibly damaging	0.94
R1269:Tenm2	UTSW	11	36,008,358 (GRCm38)	missense	possibly damaging	0.64
R1270:Tenm2	UTSW	11	36,041,659 (GRCm38)	missense	probably damaging	1.00
R1272:Tenm2	UTSW	11	36,063,177 (GRCm38)	missense	possibly damaging	0.94
R1273:Tenm2	UTSW	11	36,063,177 (GRCm38)	missense	possibly damaging	0.94
R1311:Tenm2	UTSW	11	36,068,594 (GRCm38)	splice site	probably benign
R1374:Tenm2	UTSW	11	36,008,454 (GRCm38)	missense	probably benign	0.00
R1542:Tenm2	UTSW	11	36,300,220 (GRCm38)	missense	probably damaging	0.99
R1573:Tenm2	UTSW	11	36,047,069 (GRCm38)	missense	probably damaging	1.00
R1579:Tenm2	UTSW	11	36,106,783 (GRCm38)	missense	probably damaging	1.00
R1697:Tenm2	UTSW	11	36,063,177 (GRCm38)	missense	possibly damaging	0.94
R1722:Tenm2	UTSW	11	36,008,103 (GRCm38)	missense	probably damaging	1.00
R1756:Tenm2	UTSW	11	36,063,177 (GRCm38)	missense	possibly damaging	0.94
R1793:Tenm2	UTSW	11	36,023,382 (GRCm38)	missense	probably damaging	0.99
R1950:Tenm2	UTSW	11	36,063,177 (GRCm38)	missense	possibly damaging	0.94
R1954:Tenm2	UTSW	11	36,047,547 (GRCm38)	missense	possibly damaging	0.87
R2025:Tenm2	UTSW	11	36,047,264 (GRCm38)	nonsense	probably null
R2117:Tenm2	UTSW	11	36,024,854 (GRCm38)	missense	probably damaging	1.00
R2244:Tenm2	UTSW	11	36,864,862 (GRCm38)	missense	probably damaging	0.98
R2298:Tenm2	UTSW	11	36,046,777 (GRCm38)	missense	possibly damaging	0.62
R2432:Tenm2	UTSW	11	36,027,191 (GRCm38)	missense	probably damaging	1.00
R3014:Tenm2	UTSW	11	36,023,973 (GRCm38)	missense	probably damaging	1.00
R3115:Tenm2	UTSW	11	36,023,366 (GRCm38)	missense	probably damaging	1.00
R3684:Tenm2	UTSW	11	36,051,817 (GRCm38)	missense	probably benign	0.00
R3685:Tenm2	UTSW	11	36,051,817 (GRCm38)	missense	probably benign	0.00
R3705:Tenm2	UTSW	11	36,068,326 (GRCm38)	missense	probably damaging	0.97
R3820:Tenm2	UTSW	11	36,024,320 (GRCm38)	missense	probably damaging	0.98
R3821:Tenm2	UTSW	11	36,024,320 (GRCm38)	missense	probably damaging	0.98
R3822:Tenm2	UTSW	11	36,024,320 (GRCm38)	missense	probably damaging	0.98
R3844:Tenm2	UTSW	11	36,047,538 (GRCm38)	missense	probably damaging	0.98
R3878:Tenm2	UTSW	11	36,139,574 (GRCm38)	critical splice donor site	probably null
R4019:Tenm2	UTSW	11	36,047,074 (GRCm38)	missense	probably benign	0.04
R4062:Tenm2	UTSW	11	36,008,655 (GRCm38)	missense	probably damaging	1.00
R4367:Tenm2	UTSW	11	36,027,398 (GRCm38)	missense	probably benign
R4395:Tenm2	UTSW	11	36,024,624 (GRCm38)	missense	probably benign	0.23
R4508:Tenm2	UTSW	11	36,008,345 (GRCm38)	missense	possibly damaging	0.82
R4534:Tenm2	UTSW	11	36,063,104 (GRCm38)	missense	possibly damaging	0.64
R4539:Tenm2	UTSW	11	36,046,780 (GRCm38)	missense	probably damaging	1.00
R4644:Tenm2	UTSW	11	36,047,136 (GRCm38)	missense	probably benign	0.00
R4661:Tenm2	UTSW	11	36,024,448 (GRCm38)	missense	probably damaging	0.99
R4669:Tenm2	UTSW	11	36,010,487 (GRCm38)	missense	probably damaging	1.00
R4687:Tenm2	UTSW	11	36,049,097 (GRCm38)	missense	probably benign
R4711:Tenm2	UTSW	11	36,300,212 (GRCm38)	missense	probably damaging	0.98
R4816:Tenm2	UTSW	11	36,027,290 (GRCm38)	missense	probably damaging	1.00
R4843:Tenm2	UTSW	11	36,024,020 (GRCm38)	missense	probably damaging	1.00
R4850:Tenm2	UTSW	11	36,023,488 (GRCm38)	nonsense	probably null
R4870:Tenm2	UTSW	11	36,078,569 (GRCm38)	missense	probably damaging	1.00
R5058:Tenm2	UTSW	11	36,207,080 (GRCm38)	missense	possibly damaging	0.80
R5071:Tenm2	UTSW	11	36,068,381 (GRCm38)	missense	probably damaging	0.99
R5073:Tenm2	UTSW	11	36,068,381 (GRCm38)	missense	probably damaging	0.99
R5074:Tenm2	UTSW	11	36,068,381 (GRCm38)	missense	probably damaging	0.99
R5081:Tenm2	UTSW	11	36,024,633 (GRCm38)	missense	possibly damaging	0.95
R5093:Tenm2	UTSW	11	36,944,162 (GRCm38)	missense	probably damaging	1.00
R5170:Tenm2	UTSW	11	36,024,806 (GRCm38)	missense	probably damaging	0.98
R5253:Tenm2	UTSW	11	36,047,201 (GRCm38)	nonsense	probably null
R5343:Tenm2	UTSW	11	36,069,503 (GRCm38)	missense	probably benign	0.00
R5493:Tenm2	UTSW	11	36,864,676 (GRCm38)	missense	probably benign	0.01
R5600:Tenm2	UTSW	11	36,163,714 (GRCm38)	splice site	probably null
R5677:Tenm2	UTSW	11	36,141,683 (GRCm38)	missense	probably damaging	0.98
R5703:Tenm2	UTSW	11	36,023,799 (GRCm38)	missense	probably benign	0.34
R6026:Tenm2	UTSW	11	36,072,729 (GRCm38)	critical splice donor site	probably null
R6063:Tenm2	UTSW	11	36,163,717 (GRCm38)	critical splice donor site	probably null
R6086:Tenm2	UTSW	11	36,008,646 (GRCm38)	missense	possibly damaging	0.64
R6151:Tenm2	UTSW	11	36,008,783 (GRCm38)	missense	probably damaging	1.00
R6169:Tenm2	UTSW	11	36,139,690 (GRCm38)	missense	probably damaging	0.99
R6193:Tenm2	UTSW	11	36,046,794 (GRCm38)	missense	probably damaging	1.00
R6405:Tenm2	UTSW	11	36,864,859 (GRCm38)	missense	probably benign	0.44
R6477:Tenm2	UTSW	11	36,010,507 (GRCm38)	critical splice acceptor site	probably null
R6607:Tenm2	UTSW	11	36,063,775 (GRCm38)	critical splice donor site	probably null
R6668:Tenm2	UTSW	11	36,046,765 (GRCm38)	critical splice donor site	probably null
R6825:Tenm2	UTSW	11	36,046,884 (GRCm38)	missense	probably benign	0.02
R6885:Tenm2	UTSW	11	36,023,580 (GRCm38)	missense	possibly damaging	0.95
R7017:Tenm2	UTSW	11	36,171,409 (GRCm38)	missense	probably damaging	0.98
R7115:Tenm2	UTSW	11	36,163,817 (GRCm38)	missense	probably damaging	0.99
R7153:Tenm2	UTSW	11	36,024,182 (GRCm38)	missense	probably damaging	0.98
R7173:Tenm2	UTSW	11	36,041,551 (GRCm38)	missense	probably damaging	0.99
R7199:Tenm2	UTSW	11	36,171,436 (GRCm38)	missense	probably damaging	1.00
R7205:Tenm2	UTSW	11	36,049,129 (GRCm38)	missense	probably damaging	0.99
R7250:Tenm2	UTSW	11	36,072,798 (GRCm38)	missense	probably damaging	1.00
R7290:Tenm2	UTSW	11	36,023,471 (GRCm38)	missense	probably damaging	1.00
R7366:Tenm2	UTSW	11	36,069,414 (GRCm38)	missense	probably benign	0.09
R7432:Tenm2	UTSW	11	36,864,941 (GRCm38)	missense	probably benign
R7504:Tenm2	UTSW	11	36,139,743 (GRCm38)	missense	probably damaging	1.00
R7513:Tenm2	UTSW	11	36,051,900 (GRCm38)	missense	probably benign	0.34
R7523:Tenm2	UTSW	11	36,078,581 (GRCm38)	splice site	probably null
R7527:Tenm2	UTSW	11	36,206,976 (GRCm38)	missense	probably damaging	1.00
R7648:Tenm2	UTSW	11	36,106,736 (GRCm38)	missense	probably damaging	1.00
R7653:Tenm2	UTSW	11	36,047,347 (GRCm38)	missense	probably benign	0.09
R7717:Tenm2	UTSW	11	36,864,935 (GRCm38)	missense	probably damaging	0.97
R7739:Tenm2	UTSW	11	36,069,561 (GRCm38)	missense	possibly damaging	0.50
R7762:Tenm2	UTSW	11	36,023,306 (GRCm38)	missense	possibly damaging	0.74
R7786:Tenm2	UTSW	11	36,010,449 (GRCm38)	missense	probably damaging	0.99
R7803:Tenm2	UTSW	11	36,047,116 (GRCm38)	missense	probably damaging	0.98
R7834:Tenm2	UTSW	11	36,024,854 (GRCm38)	missense	probably damaging	1.00
R7838:Tenm2	UTSW	11	36,106,799 (GRCm38)	missense	probably benign	0.02
R8073:Tenm2	UTSW	11	36,139,644 (GRCm38)	missense	possibly damaging	0.56
R8076:Tenm2	UTSW	11	36,027,221 (GRCm38)	missense	probably benign	0.23
R8109:Tenm2	UTSW	11	36,008,310 (GRCm38)	missense	probably benign
R8306:Tenm2	UTSW	11	36,069,369 (GRCm38)	missense	possibly damaging	0.52
R8352:Tenm2	UTSW	11	36,023,601 (GRCm38)	missense	probably damaging	0.98
R8452:Tenm2	UTSW	11	36,023,601 (GRCm38)	missense	probably damaging	0.98
R8864:Tenm2	UTSW	11	36,027,195 (GRCm38)	missense	possibly damaging	0.95
R8880:Tenm2	UTSW	11	36,051,961 (GRCm38)	missense	probably damaging	0.99
R8943:Tenm2	UTSW	11	36,944,034 (GRCm38)	missense	probably damaging	0.98
R8969:Tenm2	UTSW	11	36,051,861 (GRCm38)	missense	probably damaging	0.99
R9168:Tenm2	UTSW	11	36,039,895 (GRCm38)	missense	probably damaging	1.00
R9279:Tenm2	UTSW	11	36,068,476 (GRCm38)	missense	probably benign	0.00
R9294:Tenm2	UTSW	11	36,024,500 (GRCm38)	missense	probably damaging	0.98
R9320:Tenm2	UTSW	11	36,023,647 (GRCm38)	missense	probably damaging	0.99
R9373:Tenm2	UTSW	11	36,039,886 (GRCm38)	missense	probably damaging	1.00
R9408:Tenm2	UTSW	11	36,069,419 (GRCm38)	missense	probably damaging	1.00
R9410:Tenm2	UTSW	11	36,141,569 (GRCm38)	missense	probably damaging	0.99
R9454:Tenm2	UTSW	11	36,221,459 (GRCm38)	missense	probably benign
R9489:Tenm2	UTSW	11	36,943,964 (GRCm38)	missense	probably damaging	0.99
R9711:Tenm2	UTSW	11	36,024,514 (GRCm38)	missense	probably damaging	0.99
RF021:Tenm2	UTSW	11	36,024,203 (GRCm38)	missense	possibly damaging	0.95
X0018:Tenm2	UTSW	11	36,024,200 (GRCm38)	missense	probably damaging	1.00
X0063:Tenm2	UTSW	11	36,024,730 (GRCm38)	missense	probably benign
Z1088:Tenm2	UTSW	11	36,273,267 (GRCm38)	missense	probably damaging	1.00
Z1177:Tenm2	UTSW	11	36,300,335 (GRCm38)	missense	probably damaging	0.98
Z1177:Tenm2	UTSW	11	36,008,234 (GRCm38)	missense	possibly damaging	0.95
Z1177:Tenm2	UTSW	11	36,385,130 (GRCm38)	missense	probably benign	0.01

Predicted Primers

PCR Primer
(F):5'- TCAGCGCTGTATGTGAAATTGTAC -3'
(R):5'- ACATCACTGAGACGGACGAG -3'

Sequencing Primer
(F):5'- GTGAAATTGTACAAGTACTCCCCAG -3'
(R):5'- GAGAAGAAGATCAACCGCCTACG -3'

Posted On

2017-01-03