Incidental Mutation 'R5892:Tex29'
ID457245
Institutional Source Beutler Lab
Gene Symbol Tex29
Ensembl Gene ENSMUSG00000031512
Gene Nametestis expressed 29
Synonyms
MMRRC Submission 044093-MU
Accession Numbers
Is this an essential gene? Non essential (E-score: 0.000) question?
Stock #R5892 (G1)
Quality Score225
Status Validated
Chromosome8
Chromosomal Location11840474-11855761 bp(+) (GRCm38)
Type of Mutationutr 3 prime
DNA Base Change (assembly) C to T at 11854288 bp
ZygosityHeterozygous
Amino Acid Change
Ref Sequence ENSEMBL: ENSMUSP00000147894 (fasta)
Gene Model predicted gene model for transcript(s): [ENSMUST00000033909] [ENSMUST00000166638] [ENSMUST00000209692] [ENSMUST00000209704]
Predicted Effect unknown
Transcript: ENSMUST00000033909
AA Change: P125S
SMART Domains Protein: ENSMUSP00000033909
Gene: ENSMUSG00000031512
AA Change: P125S

DomainStartEndE-ValueType
transmembrane domain 57 79 N/A INTRINSIC
low complexity region 105 132 N/A INTRINSIC
Predicted Effect noncoding transcript
Transcript: ENSMUST00000132536
Predicted Effect unknown
Transcript: ENSMUST00000166638
AA Change: P125S
SMART Domains Protein: ENSMUSP00000132090
Gene: ENSMUSG00000031512
AA Change: P125S

DomainStartEndE-ValueType
Pfam:TEX29 13 88 9.6e-47 PFAM
low complexity region 105 132 N/A INTRINSIC
Predicted Effect unknown
Transcript: ENSMUST00000209692
AA Change: P143S
Predicted Effect probably benign
Transcript: ENSMUST00000209704
Meta Mutation Damage Score 0.0898 question?
Coding Region Coverage
  • 1x: 99.9%
  • 3x: 99.5%
  • 10x: 97.6%
  • 20x: 92.6%
Validation Efficiency 98% (56/57)
Allele List at MGI
Other mutations in this stock
Total: 49 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
4930524J08Rik G T 5: 99,979,265 probably benign Het
Abcb11 C T 2: 69,261,500 A893T probably damaging Het
Adtrp A T 13: 41,828,206 N30K probably benign Het
Alms1 T A 6: 85,620,903 S904T probably damaging Het
Cep170 T A 1: 176,755,387 probably null Het
Cntnap3 A G 13: 64,799,180 V145A probably damaging Het
Dclre1a T C 19: 56,547,140 E4G probably benign Het
Depdc1a G C 3: 159,526,669 A686P probably damaging Het
Dnah7b T C 1: 46,337,593 probably null Het
Enox1 A G 14: 77,486,017 probably benign Het
Fam107b A G 2: 3,778,564 E268G probably damaging Het
Fer1l6 A G 15: 58,564,068 S437G probably benign Het
Flnb C A 14: 7,907,183 T1252K probably damaging Het
Fubp1 A G 3: 152,218,314 probably benign Het
Gm20402 G A 3: 52,268,949 A50T probably benign Het
Gpr137b T C 13: 13,359,406 Y355C probably damaging Het
Gzmk C T 13: 113,173,922 probably null Het
Ino80 A T 2: 119,439,547 probably benign Het
Ints8 T C 4: 11,223,813 T677A probably damaging Het
Kat6a A G 8: 22,938,289 E1220G probably damaging Het
Lrfn5 A G 12: 61,843,418 T498A probably damaging Het
Lrp2 T A 2: 69,442,776 T4043S probably benign Het
Malrd1 A G 2: 15,614,267 N314S probably benign Het
Mfsd1 A G 3: 67,589,829 probably null Het
Muc1 C T 3: 89,230,993 P381S probably benign Het
Myh2 A T 11: 67,185,176 K730* probably null Het
Nat3 T A 8: 67,547,938 N156K probably benign Het
Nelfe T C 17: 34,854,669 probably benign Het
Nlrp1a A T 11: 71,099,645 L927Q probably damaging Het
P4ha2 A G 11: 54,120,188 Y343C probably damaging Het
Pclo A T 5: 14,521,171 Q190L probably damaging Het
Pde8a A G 7: 81,295,691 N183S probably damaging Het
Plekha2 C T 8: 25,052,365 V278I probably benign Het
Plekha6 G C 1: 133,272,307 R208P possibly damaging Het
Plxnb1 T C 9: 109,111,707 L1550P probably damaging Het
Ppox C T 1: 171,277,461 V385I probably damaging Het
Prdm16 T C 4: 154,323,259 D1170G possibly damaging Het
Prmt5 A T 14: 54,509,911 S470T probably damaging Het
Robo2 T A 16: 73,895,780 probably benign Het
Siglecg G A 7: 43,412,204 probably benign Het
Slc30a5 T C 13: 100,813,302 N367S probably damaging Het
Tmem117 T A 15: 94,638,139 V18E probably damaging Het
Tmtc2 C T 10: 105,413,505 M122I probably benign Het
Tpr T A 1: 150,407,400 N287K probably benign Het
Unc93b1 A T 19: 3,943,632 D358V probably damaging Het
Vrk2 A T 11: 26,534,372 probably benign Het
Wdr24 A T 17: 25,827,986 Q671L probably benign Het
Zfp110 C T 7: 12,848,478 T351I probably benign Het
Zfp963 T C 8: 69,743,377 D142G probably benign Het
Other mutations in Tex29
AlleleSourceChrCoordTypePredicted EffectPPH Score
IGL01284:Tex29 APN 8 11844231 nonsense probably null
R0562:Tex29 UTSW 8 11844138 splice site probably benign
R0830:Tex29 UTSW 8 11854157 missense probably benign 0.35
R4829:Tex29 UTSW 8 11855668 utr 3 prime probably benign
R5723:Tex29 UTSW 8 11854279 utr 3 prime probably benign
R5902:Tex29 UTSW 8 11854276 utr 3 prime probably benign
R5902:Tex29 UTSW 8 11854277 utr 3 prime probably benign
R5902:Tex29 UTSW 8 11855723 utr 3 prime probably benign
R7866:Tex29 UTSW 8 11844055 missense unknown
R7949:Tex29 UTSW 8 11844055 missense unknown
Predicted Primers PCR Primer
(F):5'- CATTGCAGAGCCCGTGTATG -3'
(R):5'- ATTGGAATCCTTGCCCAGC -3'

Sequencing Primer
(F):5'- CAGGGGCTTCTGTCTCCTAG -3'
(R):5'- GCCTAAAACAGTGTTGGCCATTC -3'
Posted On2017-02-15