Mutagenetix > Incidental Mutation

Incidental Mutation 'R5888:Efcab3'

457819

Institutional Source

Beutler Lab

Gene Symbol

Efcab3

Ensembl Gene

ENSMUSG00000020690

Gene Name

EF-hand calcium binding domain 3

Synonyms

Gm11639, Efcab13, 4921510J17Rik, Efcab15, Gm11639

MMRRC Submission

044089-MU

Accession Numbers

Essential gene?

Non essential (E-score: 0.000) question?

Stock #

R5888 (G1)

Quality Score

225

Status

Validated

Chromosome

Chromosomal Location

104954418-105008363 bp(+) (GRCm39)

Type of Mutation

splice site

DNA Base Change (assembly)

T to C at 104612227 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Ref Sequence

ENSEMBL: ENSMUSP00000148433 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000148007] [ENSMUST00000212287]

AlphaFold

Q80X60

Predicted Effect

unknown
Transcript: ENSMUST00000148007
AA Change: S617P

SMART Domains

Protein: ENSMUSP00000116040
Gene: ENSMUSG00000040838
AA Change: S617P

Domain	Start	End	E-Value	Type
low complexity region	40	55	N/A	INTRINSIC
low complexity region	116	129	N/A	INTRINSIC
internal_repeat_4	146	233	3.42e-6	PROSPERO
internal_repeat_3	165	247	2.21e-6	PROSPERO
low complexity region	331	348	N/A	INTRINSIC
internal_repeat_2	349	361	4.38e-8	PROSPERO
internal_repeat_2	371	383	4.38e-8	PROSPERO
low complexity region	385	640	N/A	INTRINSIC
Pfam:EF-hand_8	677	729	8.7e-6	PFAM
low complexity region	835	842	N/A	INTRINSIC
internal_repeat_1	879	1106	2.47e-14	PROSPERO
internal_repeat_4	1015	1108	3.42e-6	PROSPERO

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000175713

Predicted Effect

probably benign
Transcript: ENSMUST00000212287

Meta Mutation Damage Score

0.0898

Coding Region Coverage

1x: 99.9%
3x: 99.6%
10x: 98.2%
20x: 94.9%

Validation Efficiency

94% (96/102)

Allele List at MGI

Other mutations in this stock

Total: 92 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
Adcy1	T	A	11: 7,089,095 (GRCm39)	V503E	possibly damaging	Het
Alk	C	A	17: 72,181,938 (GRCm39)	V1362L	probably damaging	Het
Ankrd55	T	A	13: 112,492,453 (GRCm39)	I208N	possibly damaging	Het
Asap2	T	A	12: 21,268,191 (GRCm39)	I319N	probably damaging	Het
Atp11b	T	C	3: 35,891,696 (GRCm39)	I1036T	probably benign	Het
B4gat1	T	C	19: 5,089,560 (GRCm39)	F186L	probably benign	Het
C3	T	A	17: 57,521,831 (GRCm39)	T1079S	probably damaging	Het
Cacul1	G	T	19: 60,525,902 (GRCm39)	T287K	possibly damaging	Het
Cbr3	G	C	16: 93,487,614 (GRCm39)	G266R	probably damaging	Het
Cd63	T	A	10: 128,748,160 (GRCm39)		probably null	Het
Chd7	G	A	4: 8,866,382 (GRCm39)	M851I	probably damaging	Het
Chst13	T	A	6: 90,286,554 (GRCm39)	H136L	probably benign	Het
Cyp2d22	T	C	15: 82,258,014 (GRCm39)	T179A	probably benign	Het
Dclre1b	A	T	3: 103,711,053 (GRCm39)	V286E	probably damaging	Het
Defb45	G	A	2: 152,435,154 (GRCm39)		probably benign	Het
Dlg1	T	C	16: 31,610,704 (GRCm39)		probably null	Het
Dock3	A	G	9: 106,901,002 (GRCm39)	V321A	probably benign	Het
Dytn	A	T	1: 63,716,396 (GRCm39)	V59E	possibly damaging	Het
Eif2ak1	A	G	5: 143,823,733 (GRCm39)	I393M	probably damaging	Het
Fam83g	A	T	11: 61,593,420 (GRCm39)	E318V	probably benign	Het
Fbxo34	T	A	14: 47,767,176 (GRCm39)	F179I	probably damaging	Het
Fmo5	T	A	3: 97,549,041 (GRCm39)	Y230N	probably benign	Het
Fzd9	T	G	5: 135,278,317 (GRCm39)		probably null	Het
Gata2	T	C	6: 88,177,722 (GRCm39)	S251P	probably benign	Het
Gigyf1	A	G	5: 137,523,959 (GRCm39)	D1043G	probably damaging	Het
Gm10322	T	A	10: 59,452,125 (GRCm39)	S81T	probably benign	Het
Gm15517	A	T	7: 43,910,066 (GRCm39)		probably benign	Het
Haus4	T	C	14: 54,781,676 (GRCm39)	T232A	probably benign	Het
Hgfac	A	T	5: 35,202,751 (GRCm39)	H417L	probably damaging	Het
Iqgap2	T	C	13: 95,772,118 (GRCm39)	K1354E	possibly damaging	Het
Kcnk12	C	A	17: 88,054,077 (GRCm39)	R195L	probably benign	Het
Kcnn2	A	T	18: 45,725,412 (GRCm39)	I303F	probably damaging	Het
Kcnt1	T	C	2: 25,798,122 (GRCm39)	F879S	probably damaging	Het
Kndc1	T	C	7: 139,475,133 (GRCm39)	F11L	probably benign	Het
Kpna7	A	G	5: 144,926,605 (GRCm39)	F449S	probably damaging	Het
Krt77	G	T	15: 101,773,888 (GRCm39)	N255K	probably benign	Het
Lair1	A	T	7: 4,013,844 (GRCm39)	D134E	probably damaging	Het
Loxhd1	T	C	18: 77,490,211 (GRCm39)	V1318A	probably damaging	Het
Marchf10	A	T	11: 105,292,972 (GRCm39)	V145D	possibly damaging	Het
Mcpt1	T	A	14: 56,256,969 (GRCm39)	M169K	probably benign	Het
Mdc1	T	A	17: 36,158,712 (GRCm39)	V364E	probably benign	Het
Mfsd11	T	C	11: 116,762,210 (GRCm39)	F270S	probably damaging	Het
Mfsd4b2	T	G	10: 39,798,031 (GRCm39)	D108A	probably benign	Het
Mink1	A	T	11: 70,500,885 (GRCm39)		probably benign	Het
Mmp25	T	C	17: 23,850,048 (GRCm39)	Y504C	probably damaging	Het
Ms4a13	C	T	19: 11,168,870 (GRCm39)	V52I	probably benign	Het
Msh4	C	T	3: 153,573,360 (GRCm39)		probably null	Het
Muc5b	T	G	7: 141,412,158 (GRCm39)	S1701R	unknown	Het
Naalad2	A	T	9: 18,241,937 (GRCm39)	S656T	probably benign	Het
Ncapd2	T	C	6: 125,164,052 (GRCm39)	Y64C	probably damaging	Het
Ncapg2	T	A	12: 116,389,420 (GRCm39)	S347T	possibly damaging	Het
Ndufb11b	T	C	15: 81,864,872 (GRCm39)	S38P	probably benign	Het
Nipal4	T	C	11: 46,042,166 (GRCm39)	T172A	probably damaging	Het
Nrros	T	C	16: 31,961,905 (GRCm39)	K652R	probably benign	Het
Nrxn3	G	T	12: 89,478,855 (GRCm39)	A983S	possibly damaging	Het
Or4a76	T	A	2: 89,461,143 (GRCm39)	Y33F	probably damaging	Het
Or4ac1-ps1	T	C	2: 88,370,588 (GRCm39)		noncoding transcript	Het
Or4c115	T	A	2: 88,928,269 (GRCm39)	M1L	probably damaging	Het
Or4k77	T	C	2: 111,199,088 (GRCm39)	M37T	probably benign	Het
Or51m1	A	G	7: 103,578,239 (GRCm39)	T70A	possibly damaging	Het
Or8g24	A	T	9: 38,989,263 (GRCm39)	Y259*	probably null	Het
Or8k37	A	C	2: 86,469,488 (GRCm39)	L188R	probably damaging	Het
P2rx4	T	A	5: 122,857,228 (GRCm39)	S155T	probably benign	Het
P2rx4	T	G	5: 122,865,271 (GRCm39)	Y299D	probably damaging	Het
Pcsk6	A	T	7: 65,693,372 (GRCm39)	L7F	probably null	Het
Pdss2	T	C	10: 43,097,793 (GRCm39)		silent	Het
Pfkl	A	G	10: 77,827,204 (GRCm39)	V494A	possibly damaging	Het
Prep	G	T	10: 44,943,460 (GRCm39)	D12Y	possibly damaging	Het
Prg4	A	G	1: 150,328,101 (GRCm39)	F188S	probably damaging	Het
Ripor3	T	C	2: 167,839,207 (GRCm39)	Y98C	probably damaging	Het
Rnf216	T	A	5: 143,054,069 (GRCm39)		probably null	Het
Rnf24	A	G	2: 131,164,165 (GRCm39)		probably benign	Het
Rps18-ps6	G	A	13: 97,896,901 (GRCm39)	R66*	probably null	Het
Scn3a	A	G	2: 65,327,742 (GRCm39)	M916T	probably benign	Het
Scnm1	T	C	3: 95,037,596 (GRCm39)	I157V	probably benign	Het
Sh2b3	C	G	5: 121,967,084 (GRCm39)	R10P	possibly damaging	Het
Slc25a27	T	C	17: 43,960,585 (GRCm39)	D211G	probably damaging	Het
Slc36a4	A	T	9: 15,638,324 (GRCm39)	Y250F	probably damaging	Het
Slc4a1	T	A	11: 102,247,351 (GRCm39)	E448V	probably damaging	Het
Slit1	C	A	19: 41,731,735 (GRCm39)	C38F	probably damaging	Het
Spock3	T	A	8: 63,808,334 (GRCm39)	N410K	unknown	Het
Supt20	G	T	3: 54,619,628 (GRCm39)	W370L	probably benign	Het
Tas2r139	T	A	6: 42,118,430 (GRCm39)	N187K	probably damaging	Het
Tbc1d9b	G	A	11: 50,031,311 (GRCm39)	V111I	probably benign	Het
Thsd7b	T	A	1: 130,138,057 (GRCm39)	Y1578*	probably null	Het
Tln2	T	A	9: 67,136,685 (GRCm39)	I1267F	probably damaging	Het
Tnk2	G	A	16: 32,490,185 (GRCm39)	V363I	probably damaging	Het
Ttc32	A	G	12: 9,085,870 (GRCm39)	K139R	possibly damaging	Het
Vmn1r30	G	C	6: 58,412,550 (GRCm39)	T94S	possibly damaging	Het
Vmn1r90	G	A	7: 14,295,780 (GRCm39)	T106I	probably damaging	Het
Zfp677	T	A	17: 21,618,520 (GRCm39)	C526S	probably damaging	Het
Zfp831	T	G	2: 174,485,420 (GRCm39)	S32A	probably benign	Het

Other mutations in Efcab3

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00897:Efcab3	APN	11	104,990,847 (GRCm39)	missense	probably damaging	1.00
IGL01308:Efcab3	APN	11	104,611,523 (GRCm39)	missense	probably benign	0.03
IGL01483:Efcab3	APN	11	104,630,173 (GRCm39)	missense	probably benign	0.03
IGL01695:Efcab3	APN	11	104,626,889 (GRCm39)	missense	probably damaging	1.00
IGL01860:Efcab3	APN	11	104,581,747 (GRCm39)	missense	probably benign	0.16
IGL01981:Efcab3	APN	11	104,612,258 (GRCm39)	intron	probably benign
IGL01984:Efcab3	APN	11	104,629,134 (GRCm39)	missense	probably benign	0.20
IGL02023:Efcab3	APN	11	104,612,258 (GRCm39)	intron	probably benign
IGL02252:Efcab3	APN	11	104,644,753 (GRCm39)	missense	possibly damaging	0.68
IGL02886:Efcab3	APN	11	104,986,700 (GRCm39)	missense	possibly damaging	0.95
IGL03116:Efcab3	APN	11	104,612,359 (GRCm39)	missense	probably benign	0.02
IGL03141:Efcab3	APN	11	104,986,696 (GRCm39)	missense	probably damaging	0.99
IGL03242:Efcab3	APN	11	104,997,230 (GRCm39)	missense	probably damaging	1.00
IGL03274:Efcab3	APN	11	104,611,919 (GRCm39)	missense	probably benign	0.03
IGL03408:Efcab3	APN	11	104,601,447 (GRCm39)	missense	probably benign	0.03
PIT4812001:Efcab3	UTSW	11	104,990,805 (GRCm39)	missense	probably null	0.00
R0018:Efcab3	UTSW	11	104,612,378 (GRCm39)	critical splice donor site	probably null
R0068:Efcab3	UTSW	11	104,611,648 (GRCm39)	missense	probably benign	0.29
R0350:Efcab3	UTSW	11	104,581,706 (GRCm39)	missense	probably benign	0.03
R0388:Efcab3	UTSW	11	105,000,227 (GRCm39)	missense	possibly damaging	0.61
R0646:Efcab3	UTSW	11	104,611,327 (GRCm39)	missense	probably benign	0.03
R0668:Efcab3	UTSW	11	104,611,318 (GRCm39)	missense	probably benign	0.16
R0715:Efcab3	UTSW	11	104,611,706 (GRCm39)	missense	possibly damaging	0.90
R0944:Efcab3	UTSW	11	104,601,556 (GRCm39)	splice site	probably null
R1330:Efcab3	UTSW	11	104,637,116 (GRCm39)	missense	possibly damaging	0.84
R1440:Efcab3	UTSW	11	104,999,581 (GRCm39)	splice site	probably benign
R1508:Efcab3	UTSW	11	104,601,503 (GRCm39)	missense	probably benign	0.03
R1540:Efcab3	UTSW	11	104,999,726 (GRCm39)	missense	probably benign	0.07
R1643:Efcab3	UTSW	11	104,589,804 (GRCm39)	missense	probably benign	0.16
R1651:Efcab3	UTSW	11	104,611,492 (GRCm39)	missense	probably benign	0.03
R1665:Efcab3	UTSW	11	104,611,940 (GRCm39)	missense	probably benign	0.07
R1702:Efcab3	UTSW	11	104,581,832 (GRCm39)	missense	probably benign	0.03
R1711:Efcab3	UTSW	11	104,611,514 (GRCm39)	missense	probably benign	0.07
R1779:Efcab3	UTSW	11	104,611,765 (GRCm39)	missense	probably benign	0.15
R1813:Efcab3	UTSW	11	104,611,514 (GRCm39)	missense	probably benign	0.07
R1818:Efcab3	UTSW	11	104,612,333 (GRCm39)	missense	probably benign	0.10
R1896:Efcab3	UTSW	11	104,611,514 (GRCm39)	missense	probably benign	0.07
R1969:Efcab3	UTSW	11	104,637,090 (GRCm39)	missense	probably damaging	1.00
R2029:Efcab3	UTSW	11	104,990,851 (GRCm39)	missense	probably damaging	0.99
R2139:Efcab3	UTSW	11	104,642,737 (GRCm39)	missense	possibly damaging	0.53
R2165:Efcab3	UTSW	11	104,642,688 (GRCm39)	missense	possibly damaging	0.93
R2359:Efcab3	UTSW	11	104,630,106 (GRCm39)	missense	possibly damaging	0.80
R2394:Efcab3	UTSW	11	104,629,121 (GRCm39)	missense	probably benign	0.17
R2401:Efcab3	UTSW	11	104,963,144 (GRCm39)	critical splice donor site	probably null
R2406:Efcab3	UTSW	11	104,611,457 (GRCm39)	missense	probably benign	0.03
R2570:Efcab3	UTSW	11	104,624,490 (GRCm39)	missense	probably damaging	1.00
R3795:Efcab3	UTSW	11	104,624,501 (GRCm39)	missense	possibly damaging	0.94
R3901:Efcab3	UTSW	11	104,974,713 (GRCm39)	missense	possibly damaging	0.68
R4244:Efcab3	UTSW	11	105,002,629 (GRCm39)	missense	probably damaging	1.00
R4352:Efcab3	UTSW	11	104,630,140 (GRCm39)	missense	probably null	0.25
R4359:Efcab3	UTSW	11	104,624,547 (GRCm39)	splice site	probably null
R4424:Efcab3	UTSW	11	104,626,940 (GRCm39)	critical splice donor site	probably null
R4895:Efcab3	UTSW	11	105,008,227 (GRCm39)	unclassified	probably benign
R4895:Efcab3	UTSW	11	104,640,496 (GRCm39)	missense	probably damaging	1.00
R4895:Efcab3	UTSW	11	104,611,112 (GRCm39)	missense	probably benign	0.16
R5006:Efcab3	UTSW	11	104,620,503 (GRCm39)	splice site	probably null
R5066:Efcab3	UTSW	11	104,611,490 (GRCm39)	missense	probably benign	0.03
R5316:Efcab3	UTSW	11	104,967,286 (GRCm39)	missense	possibly damaging	0.80
R5329:Efcab3	UTSW	11	104,644,632 (GRCm39)	splice site	probably null
R5405:Efcab3	UTSW	11	104,612,018 (GRCm39)	missense	probably benign	0.07
R5814:Efcab3	UTSW	11	104,626,940 (GRCm39)	critical splice donor site	probably benign
R5910:Efcab3	UTSW	11	104,581,760 (GRCm39)	missense	probably benign	0.01
R5975:Efcab3	UTSW	11	104,578,375 (GRCm39)	start gained	probably benign
R6019:Efcab3	UTSW	11	104,933,728 (GRCm39)	critical splice donor site	probably null
R6028:Efcab3	UTSW	11	104,660,481 (GRCm39)	critical splice donor site	probably null
R6048:Efcab3	UTSW	11	104,835,259 (GRCm39)	missense	unknown
R6059:Efcab3	UTSW	11	104,927,595 (GRCm39)	missense	probably benign	0.03
R6147:Efcab3	UTSW	11	104,858,566 (GRCm39)	missense	unknown
R6176:Efcab3	UTSW	11	104,683,383 (GRCm39)	missense	probably benign	0.16
R6181:Efcab3	UTSW	11	104,722,159 (GRCm39)	missense	probably benign	0.25
R6196:Efcab3	UTSW	11	104,746,386 (GRCm39)	missense	probably benign	0.07
R6245:Efcab3	UTSW	11	104,675,834 (GRCm39)	missense	probably benign	0.03
R6262:Efcab3	UTSW	11	104,784,579 (GRCm39)	missense	probably benign	0.24
R6263:Efcab3	UTSW	11	104,810,312 (GRCm39)	missense	unknown
R6277:Efcab3	UTSW	11	104,901,148 (GRCm39)	missense	possibly damaging	0.49
R6338:Efcab3	UTSW	11	104,734,034 (GRCm39)	nonsense	probably null
R6355:Efcab3	UTSW	11	104,896,511 (GRCm39)	missense	probably benign	0.29
R6356:Efcab3	UTSW	11	104,784,533 (GRCm39)	missense	probably benign	0.19
R6365:Efcab3	UTSW	11	104,815,412 (GRCm39)	missense	unknown
R6378:Efcab3	UTSW	11	104,999,620 (GRCm39)	missense	possibly damaging	0.83
R6391:Efcab3	UTSW	11	104,885,143 (GRCm39)	missense	possibly damaging	0.92
R6494:Efcab3	UTSW	11	104,990,845 (GRCm39)	missense	possibly damaging	0.93
R6556:Efcab3	UTSW	11	104,899,077 (GRCm39)	missense	probably null	0.03
R6573:Efcab3	UTSW	11	104,971,461 (GRCm39)	missense	possibly damaging	0.91
R6604:Efcab3	UTSW	11	104,589,772 (GRCm39)	nonsense	probably null
R6605:Efcab3	UTSW	11	104,890,107 (GRCm39)	splice site	probably null
R6634:Efcab3	UTSW	11	104,784,609 (GRCm39)	missense	probably benign	0.17
R6723:Efcab3	UTSW	11	105,007,906 (GRCm39)	missense	possibly damaging	0.95
R6851:Efcab3	UTSW	11	104,896,521 (GRCm39)	missense	probably benign	0.03
R6862:Efcab3	UTSW	11	104,612,284 (GRCm39)	nonsense	probably null
R6949:Efcab3	UTSW	11	104,799,896 (GRCm39)	missense	probably damaging	1.00
R6970:Efcab3	UTSW	11	104,667,182 (GRCm39)	missense	probably benign	0.03
R7014:Efcab3	UTSW	11	104,584,248 (GRCm39)	missense	probably benign	0.03
R7097:Efcab3	UTSW	11	104,899,787 (GRCm39)	missense	possibly damaging	0.68
R7122:Efcab3	UTSW	11	104,899,787 (GRCm39)	missense	possibly damaging	0.68
R7124:Efcab3	UTSW	11	104,629,100 (GRCm39)	missense	probably benign	0.17
R7146:Efcab3	UTSW	11	104,913,764 (GRCm39)	missense	probably benign	0.03
R7146:Efcab3	UTSW	11	104,858,578 (GRCm39)	missense	unknown
R7154:Efcab3	UTSW	11	104,589,966 (GRCm39)	splice site	probably null
R7175:Efcab3	UTSW	11	104,838,237 (GRCm39)	missense	unknown
R7189:Efcab3	UTSW	11	104,986,690 (GRCm39)	missense	probably benign
R7198:Efcab3	UTSW	11	104,642,711 (GRCm39)	missense	probably benign	0.15
R7211:Efcab3	UTSW	11	104,615,435 (GRCm39)	critical splice donor site	probably null
R7211:Efcab3	UTSW	11	104,601,539 (GRCm39)	missense	probably benign	0.01
R7216:Efcab3	UTSW	11	104,771,375 (GRCm39)	missense	possibly damaging	0.49
R7221:Efcab3	UTSW	11	104,791,432 (GRCm39)	missense	probably benign	0.36
R7233:Efcab3	UTSW	11	104,730,669 (GRCm39)	missense	possibly damaging	0.69
R7236:Efcab3	UTSW	11	104,790,093 (GRCm39)	missense	probably benign	0.10
R7262:Efcab3	UTSW	11	104,745,432 (GRCm39)	critical splice donor site	probably null
R7289:Efcab3	UTSW	11	104,929,184 (GRCm39)	missense	probably benign	0.24
R7323:Efcab3	UTSW	11	104,920,837 (GRCm39)	missense	probably benign	0.07
R7378:Efcab3	UTSW	11	104,605,528 (GRCm39)	missense	probably benign	0.03
R7388:Efcab3	UTSW	11	104,611,871 (GRCm39)	missense	probably damaging	0.97
R7390:Efcab3	UTSW	11	104,615,411 (GRCm39)	missense	possibly damaging	0.46
R7411:Efcab3	UTSW	11	104,890,549 (GRCm39)	missense	probably benign	0.10
R7468:Efcab3	UTSW	11	104,640,526 (GRCm39)	missense	probably benign	0.17
R7483:Efcab3	UTSW	11	105,000,112 (GRCm39)	missense	probably benign	0.39
R7497:Efcab3	UTSW	11	104,653,516 (GRCm39)	critical splice donor site	probably null
R7612:Efcab3	UTSW	11	104,999,647 (GRCm39)	missense	possibly damaging	0.80
R7620:Efcab3	UTSW	11	104,722,969 (GRCm39)	missense	possibly damaging	0.95
R7638:Efcab3	UTSW	11	104,927,625 (GRCm39)	missense	probably benign	0.03
R7661:Efcab3	UTSW	11	104,617,503 (GRCm39)	missense	probably benign	0.03
R7667:Efcab3	UTSW	11	104,642,737 (GRCm39)	missense	possibly damaging	0.53
R7682:Efcab3	UTSW	11	104,855,174 (GRCm39)	splice site	probably null
R7708:Efcab3	UTSW	11	104,855,397 (GRCm39)	missense	unknown
R7719:Efcab3	UTSW	11	105,002,674 (GRCm39)	missense	probably benign	0.14
R7721:Efcab3	UTSW	11	104,615,366 (GRCm39)	nonsense	probably null
R7735:Efcab3	UTSW	11	104,962,465 (GRCm39)	missense	probably benign
R7747:Efcab3	UTSW	11	104,733,429 (GRCm39)	missense	probably damaging	0.96
R7840:Efcab3	UTSW	11	104,624,539 (GRCm39)	missense	probably benign	0.07
R7846:Efcab3	UTSW	11	104,605,571 (GRCm39)	critical splice donor site	probably null
R7893:Efcab3	UTSW	11	104,870,186 (GRCm39)	missense	unknown
R7895:Efcab3	UTSW	11	105,008,150 (GRCm39)	missense	probably benign	0.29
R7897:Efcab3	UTSW	11	104,889,061 (GRCm39)	missense	probably benign	0.24
R7936:Efcab3	UTSW	11	104,890,524 (GRCm39)	missense	possibly damaging	0.89
R7936:Efcab3	UTSW	11	104,937,385 (GRCm39)	critical splice donor site	probably null
R7959:Efcab3	UTSW	11	104,933,627 (GRCm39)	missense	probably damaging	0.96
R8031:Efcab3	UTSW	11	104,772,295 (GRCm39)	missense	possibly damaging	0.49
R8041:Efcab3	UTSW	11	104,810,305 (GRCm39)	missense	unknown
R8054:Efcab3	UTSW	11	104,621,226 (GRCm39)	missense	probably benign	0.07
R8056:Efcab3	UTSW	11	104,799,896 (GRCm39)	missense	probably damaging	0.98
R8061:Efcab3	UTSW	11	104,997,275 (GRCm39)	missense	probably benign	0.00
R8088:Efcab3	UTSW	11	104,889,072 (GRCm39)	missense	probably benign	0.10
R8112:Efcab3	UTSW	11	104,841,026 (GRCm39)	missense	unknown
R8116:Efcab3	UTSW	11	105,002,677 (GRCm39)	missense	possibly damaging	0.65
R8340:Efcab3	UTSW	11	104,876,856 (GRCm39)	missense	unknown
R8405:Efcab3	UTSW	11	104,612,024 (GRCm39)	missense	probably benign	0.02
R8413:Efcab3	UTSW	11	104,811,135 (GRCm39)	missense	unknown
R8472:Efcab3	UTSW	11	104,709,463 (GRCm39)	missense	probably benign	0.07
R8549:Efcab3	UTSW	11	104,890,521 (GRCm39)	missense	probably damaging	0.99
R8699:Efcab3	UTSW	11	104,672,072 (GRCm39)	missense	probably benign	0.03
R8711:Efcab3	UTSW	11	104,743,371 (GRCm39)	missense	probably benign	0.03
R8732:Efcab3	UTSW	11	104,695,100 (GRCm39)	missense	probably benign	0.03
R8745:Efcab3	UTSW	11	104,749,304 (GRCm39)	missense	possibly damaging	0.57
R8806:Efcab3	UTSW	11	104,928,695 (GRCm39)	missense	probably benign	0.07
R8810:Efcab3	UTSW	11	104,805,721 (GRCm39)	missense	unknown
R8845:Efcab3	UTSW	11	104,899,787 (GRCm39)	missense	possibly damaging	0.68
R8870:Efcab3	UTSW	11	104,791,500 (GRCm39)	missense	probably benign	0.07
R8872:Efcab3	UTSW	11	104,760,880 (GRCm39)	missense	probably benign	0.19
R8879:Efcab3	UTSW	11	104,581,781 (GRCm39)	missense	probably benign	0.03
R8924:Efcab3	UTSW	11	104,806,253 (GRCm39)	frame shift	probably null
R8954:Efcab3	UTSW	11	104,909,525 (GRCm39)	critical splice donor site	probably null
R8960:Efcab3	UTSW	11	104,820,772 (GRCm39)	splice site	probably benign
R8975:Efcab3	UTSW	11	104,954,415 (GRCm39)	missense	probably benign	0.17
R8988:Efcab3	UTSW	11	104,911,352 (GRCm39)	missense	probably benign	0.07
R8998:Efcab3	UTSW	11	104,640,477 (GRCm39)	missense	probably benign	0.09
R8999:Efcab3	UTSW	11	104,640,477 (GRCm39)	missense	probably benign	0.09
R9002:Efcab3	UTSW	11	104,920,822 (GRCm39)	missense	probably damaging	0.99
R9012:Efcab3	UTSW	11	104,711,347 (GRCm39)	critical splice donor site	probably null
R9036:Efcab3	UTSW	11	104,927,601 (GRCm39)	missense	probably benign	0.03
R9037:Efcab3	UTSW	11	104,803,791 (GRCm39)	missense	unknown
R9059:Efcab3	UTSW	11	104,642,689 (GRCm39)	missense	possibly damaging	0.73
R9066:Efcab3	UTSW	11	104,631,688 (GRCm39)	intron	probably benign
R9122:Efcab3	UTSW	11	104,856,605 (GRCm39)	missense	unknown
R9125:Efcab3	UTSW	11	104,736,360 (GRCm39)	missense	probably damaging	1.00
R9127:Efcab3	UTSW	11	104,741,407 (GRCm39)	missense	probably benign	0.07
R9171:Efcab3	UTSW	11	104,800,708 (GRCm39)	missense	probably benign	0.36
R9219:Efcab3	UTSW	11	104,836,691 (GRCm39)	missense	unknown
R9224:Efcab3	UTSW	11	104,661,801 (GRCm39)	missense	probably benign	0.07
R9235:Efcab3	UTSW	11	104,907,987 (GRCm39)	missense	probably benign	0.19
R9294:Efcab3	UTSW	11	104,722,126 (GRCm39)	missense	probably benign	0.24
R9318:Efcab3	UTSW	11	104,856,648 (GRCm39)	critical splice donor site	probably null
R9322:Efcab3	UTSW	11	104,765,199 (GRCm39)	missense	probably benign	0.36
R9361:Efcab3	UTSW	11	104,896,524 (GRCm39)	missense	probably benign	0.03
R9408:Efcab3	UTSW	11	104,621,255 (GRCm39)	critical splice donor site	probably null
R9434:Efcab3	UTSW	11	104,899,863 (GRCm39)	missense	probably benign	0.24
R9477:Efcab3	UTSW	11	104,836,698 (GRCm39)	missense	unknown
R9658:Efcab3	UTSW	11	104,611,120 (GRCm39)	missense	probably benign	0.03
R9719:Efcab3	UTSW	11	104,867,912 (GRCm39)	missense	unknown
R9751:Efcab3	UTSW	11	104,783,911 (GRCm39)	missense	probably benign	0.19
R9763:Efcab3	UTSW	11	104,890,485 (GRCm39)	missense	possibly damaging	0.89
X0026:Efcab3	UTSW	11	105,007,937 (GRCm39)	missense	probably benign	0.03
X0026:Efcab3	UTSW	11	104,611,801 (GRCm39)	missense	probably benign	0.07
Z1088:Efcab3	UTSW	11	104,642,728 (GRCm39)	missense	probably damaging	0.96
Z1176:Efcab3	UTSW	11	104,990,872 (GRCm39)	missense	probably damaging	1.00
Z1176:Efcab3	UTSW	11	104,892,793 (GRCm39)	missense	probably benign	0.29
Z1176:Efcab3	UTSW	11	104,999,598 (GRCm39)	nonsense	probably null
Z1177:Efcab3	UTSW	11	104,711,344 (GRCm39)	missense	probably benign	0.03
Z1177:Efcab3	UTSW	11	104,630,164 (GRCm39)	nonsense	probably null
Z1177:Efcab3	UTSW	11	104,814,845 (GRCm39)	missense	unknown

Predicted Primers

PCR Primer
(F):5'- TGATTCAAGCCTCAAGAAGTCAC -3'
(R):5'- TGAAGTGCTCGGAAACCTAAGTC -3'

Sequencing Primer
(F):5'- CCGGATAGAAGTGATTCAAGCCTC -3'
(R):5'- CCTGACTTAGGCATATGGTACTGAC -3'

Posted On

2017-02-15