Incidental Mutation 'R5888:Iqgap2'
| ID |
457825 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Iqgap2
|
| Ensembl Gene |
ENSMUSG00000021676 |
| Gene Name |
IQ motif containing GTPase activating protein 2 |
| Synonyms |
4933417J23Rik |
| MMRRC Submission |
044089-MU
|
| Accession Numbers |
|
| Essential gene? |
Non essential
(E-score: 0.000)
|
| Stock # |
R5888 (G1)
|
| Quality Score |
225 |
|
Status
|
Validated
|
| Chromosome |
13 |
| Chromosomal Location |
95763685-96028788 bp(-) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
T to C
at 95772118 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Lysine to Glutamic Acid
at position 1354
(K1354E)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000067685
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000068603]
|
| AlphaFold |
Q3UQ44 |
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000068603
AA Change: K1354E
PolyPhen 2
Score 0.890 (Sensitivity: 0.82; Specificity: 0.94)
|
| SMART Domains |
Protein: ENSMUSP00000067685
Gene: ENSMUSG00000021676
AA Change: K1354E
| Domain | Start | End | E-Value | Type |
|---|
|
CH
|
43 |
152 |
3.32e-16 |
SMART |
|
coiled coil region
|
253 |
276 |
N/A |
INTRINSIC |
|
low complexity region
|
469 |
480 |
N/A |
INTRINSIC |
|
IQ
|
689 |
711 |
1.38e-4 |
SMART |
|
IQ
|
719 |
741 |
7.36e0 |
SMART |
|
IQ
|
749 |
771 |
2.43e1 |
SMART |
|
coiled coil region
|
799 |
828 |
N/A |
INTRINSIC |
|
RasGAP
|
905 |
1258 |
2.6e-120 |
SMART |
|
Pfam:RasGAP_C
|
1367 |
1498 |
3.2e-40 |
PFAM |
|
| Meta Mutation Damage Score |
0.1101 |
| Coding Region Coverage |
- 1x: 99.9%
- 3x: 99.6%
- 10x: 98.2%
- 20x: 94.9%
|
| Validation Efficiency |
94% (96/102) |
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene encodes a member of the IQGAP family. The protein contains three IQ domains, one calponin homology domain, one Ras-GAP domain and one WW domain. It interacts with components of the cytoskeleton, with cell adhesion molecules, and with several signaling molecules to regulate cell morphology and motility. [provided by RefSeq, Jul 2008]
PHENOTYPE: Mice homozygous for a null mutation display reduced survival with increased incidence of hepatocellular carcinomas, increased hepatocyte apoptosis, and hepatocyte mitochondrial abnormalities. [provided by MGI curators]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 92 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Adcy1 |
T |
A |
11: 7,089,095 (GRCm39) |
V503E |
possibly damaging |
Het |
| Alk |
C |
A |
17: 72,181,938 (GRCm39) |
V1362L |
probably damaging |
Het |
| Ankrd55 |
T |
A |
13: 112,492,453 (GRCm39) |
I208N |
possibly damaging |
Het |
| Asap2 |
T |
A |
12: 21,268,191 (GRCm39) |
I319N |
probably damaging |
Het |
| Atp11b |
T |
C |
3: 35,891,696 (GRCm39) |
I1036T |
probably benign |
Het |
| B4gat1 |
T |
C |
19: 5,089,560 (GRCm39) |
F186L |
probably benign |
Het |
| C3 |
T |
A |
17: 57,521,831 (GRCm39) |
T1079S |
probably damaging |
Het |
| Cacul1 |
G |
T |
19: 60,525,902 (GRCm39) |
T287K |
possibly damaging |
Het |
| Cbr3 |
G |
C |
16: 93,487,614 (GRCm39) |
G266R |
probably damaging |
Het |
| Cd63 |
T |
A |
10: 128,748,160 (GRCm39) |
|
probably null |
Het |
| Chd7 |
G |
A |
4: 8,866,382 (GRCm39) |
M851I |
probably damaging |
Het |
| Chst13 |
T |
A |
6: 90,286,554 (GRCm39) |
H136L |
probably benign |
Het |
| Cyp2d22 |
T |
C |
15: 82,258,014 (GRCm39) |
T179A |
probably benign |
Het |
| Dclre1b |
A |
T |
3: 103,711,053 (GRCm39) |
V286E |
probably damaging |
Het |
| Defb45 |
G |
A |
2: 152,435,154 (GRCm39) |
|
probably benign |
Het |
| Dlg1 |
T |
C |
16: 31,610,704 (GRCm39) |
|
probably null |
Het |
| Dock3 |
A |
G |
9: 106,901,002 (GRCm39) |
V321A |
probably benign |
Het |
| Dytn |
A |
T |
1: 63,716,396 (GRCm39) |
V59E |
possibly damaging |
Het |
| Efcab3 |
T |
C |
11: 104,612,227 (GRCm39) |
|
probably benign |
Het |
| Eif2ak1 |
A |
G |
5: 143,823,733 (GRCm39) |
I393M |
probably damaging |
Het |
| Fam83g |
A |
T |
11: 61,593,420 (GRCm39) |
E318V |
probably benign |
Het |
| Fbxo34 |
T |
A |
14: 47,767,176 (GRCm39) |
F179I |
probably damaging |
Het |
| Fmo5 |
T |
A |
3: 97,549,041 (GRCm39) |
Y230N |
probably benign |
Het |
| Fzd9 |
T |
G |
5: 135,278,317 (GRCm39) |
|
probably null |
Het |
| Gata2 |
T |
C |
6: 88,177,722 (GRCm39) |
S251P |
probably benign |
Het |
| Gigyf1 |
A |
G |
5: 137,523,959 (GRCm39) |
D1043G |
probably damaging |
Het |
| Gm10322 |
T |
A |
10: 59,452,125 (GRCm39) |
S81T |
probably benign |
Het |
| Gm15517 |
A |
T |
7: 43,910,066 (GRCm39) |
|
probably benign |
Het |
| Haus4 |
T |
C |
14: 54,781,676 (GRCm39) |
T232A |
probably benign |
Het |
| Hgfac |
A |
T |
5: 35,202,751 (GRCm39) |
H417L |
probably damaging |
Het |
| Kcnk12 |
C |
A |
17: 88,054,077 (GRCm39) |
R195L |
probably benign |
Het |
| Kcnn2 |
A |
T |
18: 45,725,412 (GRCm39) |
I303F |
probably damaging |
Het |
| Kcnt1 |
T |
C |
2: 25,798,122 (GRCm39) |
F879S |
probably damaging |
Het |
| Kndc1 |
T |
C |
7: 139,475,133 (GRCm39) |
F11L |
probably benign |
Het |
| Kpna7 |
A |
G |
5: 144,926,605 (GRCm39) |
F449S |
probably damaging |
Het |
| Krt77 |
G |
T |
15: 101,773,888 (GRCm39) |
N255K |
probably benign |
Het |
| Lair1 |
A |
T |
7: 4,013,844 (GRCm39) |
D134E |
probably damaging |
Het |
| Loxhd1 |
T |
C |
18: 77,490,211 (GRCm39) |
V1318A |
probably damaging |
Het |
| Marchf10 |
A |
T |
11: 105,292,972 (GRCm39) |
V145D |
possibly damaging |
Het |
| Mcpt1 |
T |
A |
14: 56,256,969 (GRCm39) |
M169K |
probably benign |
Het |
| Mdc1 |
T |
A |
17: 36,158,712 (GRCm39) |
V364E |
probably benign |
Het |
| Mfsd11 |
T |
C |
11: 116,762,210 (GRCm39) |
F270S |
probably damaging |
Het |
| Mfsd4b2 |
T |
G |
10: 39,798,031 (GRCm39) |
D108A |
probably benign |
Het |
| Mink1 |
A |
T |
11: 70,500,885 (GRCm39) |
|
probably benign |
Het |
| Mmp25 |
T |
C |
17: 23,850,048 (GRCm39) |
Y504C |
probably damaging |
Het |
| Ms4a13 |
C |
T |
19: 11,168,870 (GRCm39) |
V52I |
probably benign |
Het |
| Msh4 |
C |
T |
3: 153,573,360 (GRCm39) |
|
probably null |
Het |
| Muc5b |
T |
G |
7: 141,412,158 (GRCm39) |
S1701R |
unknown |
Het |
| Naalad2 |
A |
T |
9: 18,241,937 (GRCm39) |
S656T |
probably benign |
Het |
| Ncapd2 |
T |
C |
6: 125,164,052 (GRCm39) |
Y64C |
probably damaging |
Het |
| Ncapg2 |
T |
A |
12: 116,389,420 (GRCm39) |
S347T |
possibly damaging |
Het |
| Ndufb11b |
T |
C |
15: 81,864,872 (GRCm39) |
S38P |
probably benign |
Het |
| Nipal4 |
T |
C |
11: 46,042,166 (GRCm39) |
T172A |
probably damaging |
Het |
| Nrros |
T |
C |
16: 31,961,905 (GRCm39) |
K652R |
probably benign |
Het |
| Nrxn3 |
G |
T |
12: 89,478,855 (GRCm39) |
A983S |
possibly damaging |
Het |
| Or4a76 |
T |
A |
2: 89,461,143 (GRCm39) |
Y33F |
probably damaging |
Het |
| Or4ac1-ps1 |
T |
C |
2: 88,370,588 (GRCm39) |
|
noncoding transcript |
Het |
| Or4c115 |
T |
A |
2: 88,928,269 (GRCm39) |
M1L |
probably damaging |
Het |
| Or4k77 |
T |
C |
2: 111,199,088 (GRCm39) |
M37T |
probably benign |
Het |
| Or51m1 |
A |
G |
7: 103,578,239 (GRCm39) |
T70A |
possibly damaging |
Het |
| Or8g24 |
A |
T |
9: 38,989,263 (GRCm39) |
Y259* |
probably null |
Het |
| Or8k37 |
A |
C |
2: 86,469,488 (GRCm39) |
L188R |
probably damaging |
Het |
| P2rx4 |
T |
A |
5: 122,857,228 (GRCm39) |
S155T |
probably benign |
Het |
| P2rx4 |
T |
G |
5: 122,865,271 (GRCm39) |
Y299D |
probably damaging |
Het |
| Pcsk6 |
A |
T |
7: 65,693,372 (GRCm39) |
L7F |
probably null |
Het |
| Pdss2 |
T |
C |
10: 43,097,793 (GRCm39) |
|
silent |
Het |
| Pfkl |
A |
G |
10: 77,827,204 (GRCm39) |
V494A |
possibly damaging |
Het |
| Prep |
G |
T |
10: 44,943,460 (GRCm39) |
D12Y |
possibly damaging |
Het |
| Prg4 |
A |
G |
1: 150,328,101 (GRCm39) |
F188S |
probably damaging |
Het |
| Ripor3 |
T |
C |
2: 167,839,207 (GRCm39) |
Y98C |
probably damaging |
Het |
| Rnf216 |
T |
A |
5: 143,054,069 (GRCm39) |
|
probably null |
Het |
| Rnf24 |
A |
G |
2: 131,164,165 (GRCm39) |
|
probably benign |
Het |
| Rps18-ps6 |
G |
A |
13: 97,896,901 (GRCm39) |
R66* |
probably null |
Het |
| Scn3a |
A |
G |
2: 65,327,742 (GRCm39) |
M916T |
probably benign |
Het |
| Scnm1 |
T |
C |
3: 95,037,596 (GRCm39) |
I157V |
probably benign |
Het |
| Sh2b3 |
C |
G |
5: 121,967,084 (GRCm39) |
R10P |
possibly damaging |
Het |
| Slc25a27 |
T |
C |
17: 43,960,585 (GRCm39) |
D211G |
probably damaging |
Het |
| Slc36a4 |
A |
T |
9: 15,638,324 (GRCm39) |
Y250F |
probably damaging |
Het |
| Slc4a1 |
T |
A |
11: 102,247,351 (GRCm39) |
E448V |
probably damaging |
Het |
| Slit1 |
C |
A |
19: 41,731,735 (GRCm39) |
C38F |
probably damaging |
Het |
| Spock3 |
T |
A |
8: 63,808,334 (GRCm39) |
N410K |
unknown |
Het |
| Supt20 |
G |
T |
3: 54,619,628 (GRCm39) |
W370L |
probably benign |
Het |
| Tas2r139 |
T |
A |
6: 42,118,430 (GRCm39) |
N187K |
probably damaging |
Het |
| Tbc1d9b |
G |
A |
11: 50,031,311 (GRCm39) |
V111I |
probably benign |
Het |
| Thsd7b |
T |
A |
1: 130,138,057 (GRCm39) |
Y1578* |
probably null |
Het |
| Tln2 |
T |
A |
9: 67,136,685 (GRCm39) |
I1267F |
probably damaging |
Het |
| Tnk2 |
G |
A |
16: 32,490,185 (GRCm39) |
V363I |
probably damaging |
Het |
| Ttc32 |
A |
G |
12: 9,085,870 (GRCm39) |
K139R |
possibly damaging |
Het |
| Vmn1r30 |
G |
C |
6: 58,412,550 (GRCm39) |
T94S |
possibly damaging |
Het |
| Vmn1r90 |
G |
A |
7: 14,295,780 (GRCm39) |
T106I |
probably damaging |
Het |
| Zfp677 |
T |
A |
17: 21,618,520 (GRCm39) |
C526S |
probably damaging |
Het |
| Zfp831 |
T |
G |
2: 174,485,420 (GRCm39) |
S32A |
probably benign |
Het |
|
| Other mutations in Iqgap2 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00799:Iqgap2
|
APN |
13 |
95,794,452 (GRCm39) |
splice site |
probably benign |
|
|
IGL01968:Iqgap2
|
APN |
13 |
95,772,090 (GRCm39) |
missense |
possibly damaging |
0.80 |
|
IGL02049:Iqgap2
|
APN |
13 |
95,811,913 (GRCm39) |
splice site |
probably benign |
|
|
IGL02195:Iqgap2
|
APN |
13 |
95,798,242 (GRCm39) |
splice site |
probably benign |
|
|
IGL02387:Iqgap2
|
APN |
13 |
95,826,209 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL02634:Iqgap2
|
APN |
13 |
95,764,622 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02666:Iqgap2
|
APN |
13 |
95,764,564 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02685:Iqgap2
|
APN |
13 |
95,807,912 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02927:Iqgap2
|
APN |
13 |
95,861,184 (GRCm39) |
missense |
possibly damaging |
0.62 |
|
IGL02943:Iqgap2
|
APN |
13 |
95,798,243 (GRCm39) |
splice site |
probably benign |
|
|
IGL03167:Iqgap2
|
APN |
13 |
95,821,406 (GRCm39) |
missense |
probably benign |
0.34 |
|
IGL03169:Iqgap2
|
APN |
13 |
95,867,785 (GRCm39) |
splice site |
probably null |
|
|
IGL03293:Iqgap2
|
APN |
13 |
95,867,942 (GRCm39) |
missense |
probably damaging |
1.00 |
|
G1Funyon:Iqgap2
|
UTSW |
13 |
95,818,659 (GRCm39) |
critical splice donor site |
probably null |
|
|
R0257:Iqgap2
|
UTSW |
13 |
95,861,052 (GRCm39) |
critical splice donor site |
probably null |
|
|
R0335:Iqgap2
|
UTSW |
13 |
95,772,141 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R0360:Iqgap2
|
UTSW |
13 |
95,867,783 (GRCm39) |
splice site |
probably benign |
|
|
R0364:Iqgap2
|
UTSW |
13 |
95,867,783 (GRCm39) |
splice site |
probably benign |
|
|
R0419:Iqgap2
|
UTSW |
13 |
95,826,207 (GRCm39) |
critical splice donor site |
probably null |
|
|
R1229:Iqgap2
|
UTSW |
13 |
95,768,673 (GRCm39) |
missense |
probably benign |
0.32 |
|
R1290:Iqgap2
|
UTSW |
13 |
95,805,021 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1397:Iqgap2
|
UTSW |
13 |
95,768,673 (GRCm39) |
missense |
probably benign |
0.32 |
|
R1498:Iqgap2
|
UTSW |
13 |
95,783,313 (GRCm39) |
missense |
probably benign |
|
|
R1513:Iqgap2
|
UTSW |
13 |
95,766,518 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1630:Iqgap2
|
UTSW |
13 |
95,826,293 (GRCm39) |
missense |
probably benign |
|
|
R2088:Iqgap2
|
UTSW |
13 |
96,028,171 (GRCm39) |
critical splice donor site |
probably null |
|
|
R2928:Iqgap2
|
UTSW |
13 |
95,818,744 (GRCm39) |
missense |
probably benign |
|
|
R3026:Iqgap2
|
UTSW |
13 |
95,809,564 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
R3720:Iqgap2
|
UTSW |
13 |
95,805,036 (GRCm39) |
splice site |
probably null |
|
|
R3846:Iqgap2
|
UTSW |
13 |
95,810,186 (GRCm39) |
splice site |
probably benign |
|
|
R4056:Iqgap2
|
UTSW |
13 |
95,886,541 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4077:Iqgap2
|
UTSW |
13 |
95,794,375 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4353:Iqgap2
|
UTSW |
13 |
95,807,904 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4517:Iqgap2
|
UTSW |
13 |
95,800,569 (GRCm39) |
critical splice donor site |
probably null |
|
|
R4628:Iqgap2
|
UTSW |
13 |
95,899,837 (GRCm39) |
missense |
probably benign |
0.17 |
|
R4686:Iqgap2
|
UTSW |
13 |
95,858,117 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R4724:Iqgap2
|
UTSW |
13 |
95,772,005 (GRCm39) |
missense |
possibly damaging |
0.73 |
|
R4826:Iqgap2
|
UTSW |
13 |
95,899,783 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4847:Iqgap2
|
UTSW |
13 |
95,810,251 (GRCm39) |
missense |
probably benign |
0.19 |
|
R4967:Iqgap2
|
UTSW |
13 |
95,766,514 (GRCm39) |
missense |
probably benign |
0.00 |
|
R4973:Iqgap2
|
UTSW |
13 |
95,794,305 (GRCm39) |
splice site |
probably null |
|
|
R5010:Iqgap2
|
UTSW |
13 |
95,810,251 (GRCm39) |
missense |
probably benign |
0.19 |
|
R5086:Iqgap2
|
UTSW |
13 |
95,772,088 (GRCm39) |
missense |
probably benign |
0.01 |
|
R5496:Iqgap2
|
UTSW |
13 |
95,766,561 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5512:Iqgap2
|
UTSW |
13 |
95,811,884 (GRCm39) |
nonsense |
probably null |
|
|
R5629:Iqgap2
|
UTSW |
13 |
95,768,682 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5824:Iqgap2
|
UTSW |
13 |
95,811,880 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5830:Iqgap2
|
UTSW |
13 |
95,811,880 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5831:Iqgap2
|
UTSW |
13 |
95,811,880 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5832:Iqgap2
|
UTSW |
13 |
95,811,880 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5833:Iqgap2
|
UTSW |
13 |
95,811,880 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5834:Iqgap2
|
UTSW |
13 |
95,811,880 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5852:Iqgap2
|
UTSW |
13 |
95,811,880 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5889:Iqgap2
|
UTSW |
13 |
95,768,550 (GRCm39) |
missense |
probably benign |
0.00 |
|
R6093:Iqgap2
|
UTSW |
13 |
95,765,471 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R6141:Iqgap2
|
UTSW |
13 |
95,858,194 (GRCm39) |
splice site |
probably null |
|
|
R6404:Iqgap2
|
UTSW |
13 |
95,865,985 (GRCm39) |
missense |
probably benign |
0.28 |
|
R6434:Iqgap2
|
UTSW |
13 |
95,819,441 (GRCm39) |
missense |
possibly damaging |
0.85 |
|
R6648:Iqgap2
|
UTSW |
13 |
95,818,719 (GRCm39) |
missense |
probably benign |
0.27 |
|
R6658:Iqgap2
|
UTSW |
13 |
95,796,840 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6903:Iqgap2
|
UTSW |
13 |
95,797,565 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7223:Iqgap2
|
UTSW |
13 |
95,765,480 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7327:Iqgap2
|
UTSW |
13 |
95,772,163 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7371:Iqgap2
|
UTSW |
13 |
95,836,846 (GRCm39) |
splice site |
probably null |
|
|
R7378:Iqgap2
|
UTSW |
13 |
95,869,398 (GRCm39) |
critical splice donor site |
probably null |
|
|
R7441:Iqgap2
|
UTSW |
13 |
95,764,584 (GRCm39) |
missense |
probably benign |
0.23 |
|
R7575:Iqgap2
|
UTSW |
13 |
95,798,131 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7671:Iqgap2
|
UTSW |
13 |
95,764,627 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R7713:Iqgap2
|
UTSW |
13 |
95,867,952 (GRCm39) |
missense |
probably benign |
0.01 |
|
R7806:Iqgap2
|
UTSW |
13 |
95,818,765 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7893:Iqgap2
|
UTSW |
13 |
95,826,217 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R8052:Iqgap2
|
UTSW |
13 |
95,794,387 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R8121:Iqgap2
|
UTSW |
13 |
95,861,076 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8261:Iqgap2
|
UTSW |
13 |
95,772,078 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8301:Iqgap2
|
UTSW |
13 |
95,818,659 (GRCm39) |
critical splice donor site |
probably null |
|
|
R8369:Iqgap2
|
UTSW |
13 |
95,798,111 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8485:Iqgap2
|
UTSW |
13 |
95,796,659 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R8709:Iqgap2
|
UTSW |
13 |
95,796,713 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R8710:Iqgap2
|
UTSW |
13 |
95,796,756 (GRCm39) |
missense |
probably benign |
0.24 |
|
R8737:Iqgap2
|
UTSW |
13 |
95,802,258 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8845:Iqgap2
|
UTSW |
13 |
95,794,392 (GRCm39) |
missense |
possibly damaging |
0.60 |
|
R8902:Iqgap2
|
UTSW |
13 |
95,818,711 (GRCm39) |
missense |
probably benign |
0.16 |
|
R8957:Iqgap2
|
UTSW |
13 |
95,772,154 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9153:Iqgap2
|
UTSW |
13 |
95,844,547 (GRCm39) |
missense |
probably benign |
|
|
R9259:Iqgap2
|
UTSW |
13 |
95,766,561 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9290:Iqgap2
|
UTSW |
13 |
95,886,523 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9414:Iqgap2
|
UTSW |
13 |
95,783,349 (GRCm39) |
missense |
|
|
|
R9432:Iqgap2
|
UTSW |
13 |
95,774,261 (GRCm39) |
missense |
probably benign |
|
|
R9747:Iqgap2
|
UTSW |
13 |
95,821,505 (GRCm39) |
missense |
probably damaging |
1.00 |
|
X0066:Iqgap2
|
UTSW |
13 |
95,807,891 (GRCm39) |
missense |
probably damaging |
0.98 |
|
Z1176:Iqgap2
|
UTSW |
13 |
95,867,951 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
| Predicted Primers |
PCR Primer
(F):5'- TGCCAACAAAGGTCTAGGTGG -3'
(R):5'- CTTTGGCCAAATTAGGTCCAG -3'
Sequencing Primer
(F):5'- TCTAGGTGGAAAAGAAAGCTATTCCC -3'
(R):5'- GGCCAAATTAGGTCCAGTATTACATC -3'
|
| Posted On |
2017-02-15 |
Incidental Mutation