Mutagenetix > Incidental Mutation

Incidental Mutation 'R5930:Dnah10'

460155

Institutional Source

Beutler Lab

Gene Symbol

Dnah10

Ensembl Gene

ENSMUSG00000038011

Gene Name

dynein, axonemal, heavy chain 10

Synonyms

Dnahc10

MMRRC Submission

044125-MU

Accession Numbers

Essential gene?

Non essential (E-score: 0.000) question?

Stock #

R5930 (G1)

Quality Score

225

Status

Validated

Chromosome

Chromosomal Location

124725085-124834308 bp(+) (GRCm38)

Type of Mutation

critical splice donor site (2 bp from exon)

DNA Base Change (assembly)

T to C at 124791791 bp (GRCm38)

Zygosity

Heterozygous

Amino Acid Change

Ref Sequence

ENSEMBL: ENSMUSP00000114593 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000058440] [ENSMUST00000141137]

AlphaFold

no structure available at present

Predicted Effect

probably null
Transcript: ENSMUST00000058440

SMART Domains

Protein: ENSMUSP00000062995
Gene: ENSMUSG00000038011

Domain	Start	End	E-Value	Type
low complexity region	63	72	N/A	INTRINSIC
low complexity region	80	86	N/A	INTRINSIC
coiled coil region	260	282	N/A	INTRINSIC
Pfam:DHC_N1	305	878	9.1e-154	PFAM
coiled coil region	1191	1218	N/A	INTRINSIC
coiled coil region	1337	1360	N/A	INTRINSIC
Pfam:DHC_N2	1374	1782	1.7e-142	PFAM
AAA	1946	2082	2.51e-1	SMART
AAA	2225	2373	6.91e-1	SMART
low complexity region	2444	2464	N/A	INTRINSIC
AAA	2567	2720	2.29e-2	SMART
Pfam:AAA_8	2886	3153	9.8e-87	PFAM
Pfam:MT	3165	3502	9.1e-53	PFAM
Pfam:AAA_9	3522	3747	2.3e-90	PFAM
Pfam:Dynein_heavy	3884	4588	7.6e-240	PFAM

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000126998

Predicted Effect

probably null
Transcript: ENSMUST00000141137

SMART Domains

Protein: ENSMUSP00000114593
Gene: ENSMUSG00000038011

Domain	Start	End	E-Value	Type
low complexity region	63	72	N/A	INTRINSIC
low complexity region	80	86	N/A	INTRINSIC
coiled coil region	260	282	N/A	INTRINSIC
Pfam:DHC_N1	304	607	4.3e-57	PFAM
Pfam:DHC_N1	598	823	1.2e-39	PFAM
coiled coil region	1134	1161	N/A	INTRINSIC
coiled coil region	1280	1303	N/A	INTRINSIC
Pfam:DHC_N2	1315	1727	7.3e-135	PFAM
AAA	1889	2025	4e-3	SMART
AAA	2168	2316	1.1e-2	SMART
low complexity region	2387	2407	N/A	INTRINSIC
AAA	2510	2663	3.6e-4	SMART
Pfam:AAA_8	2829	3096	2.5e-83	PFAM
Pfam:MT	3108	3445	1.2e-50	PFAM
Pfam:AAA_9	3461	3691	6.7e-59	PFAM
Pfam:Dynein_heavy	3821	4532	1.9e-231	PFAM

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000198055

Meta Mutation Damage Score

0.9489

Coding Region Coverage

1x: 99.9%
3x: 99.6%
10x: 98.1%
20x: 94.5%

Validation Efficiency

94% (102/109)

MGI Phenotype

FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] Dyneins are microtubule-associated motor protein complexes composed of several heavy, light, and intermediate chains. The axonemal dyneins, found in cilia and flagella, are components of the outer and inner dynein arms attached to the peripheral microtubule doublets. DNAH10 is an inner arm dynein heavy chain (Maiti et al., 2000 [PubMed 11175280]).[supplied by OMIM, Mar 2008]

Allele List at MGI

All alleles(2) : Gene trapped(2)

Other mutations in this stock

Total: 97 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
Adgrv1	C	T	13: 81,397,451 (GRCm38)	V5572I	probably benign	Het
AF366264	T	A	8: 13,837,263 (GRCm38)	D276V	probably benign	Het
Agap1	C	T	1: 89,843,096 (GRCm38)	T656I	probably damaging	Het
Als2cl	C	T	9: 110,887,364 (GRCm38)	R247W	probably damaging	Het
Ankfy1	A	T	11: 72,712,245 (GRCm38)	R33S	probably benign	Het
Ano5	T	C	7: 51,585,331 (GRCm38)	F671L	probably damaging	Het
Arhgap26	A	G	18: 39,150,092 (GRCm38)	M361V	probably damaging	Het
Bckdk	A	G	7: 127,905,973 (GRCm38)	E175G	probably damaging	Het
Bptf	G	T	11: 107,073,196 (GRCm38)	T1724K	probably damaging	Het
Btn2a2	T	A	13: 23,486,228 (GRCm38)	I112F	probably damaging	Het
Cd163l1	C	T	7: 140,230,446 (GRCm38)	P984S	probably benign	Het
Cln8	T	A	8: 14,896,621 (GRCm38)	W212R	probably damaging	Het
Cnbd1	T	C	4: 18,886,119 (GRCm38)	E300G	probably benign	Het
Cnksr3	T	C	10: 7,142,993 (GRCm38)	I173V	probably benign	Het
Cntn2	T	A	1: 132,523,432 (GRCm38)	D484V	probably damaging	Het
Cyp4a14	C	A	4: 115,491,410 (GRCm38)	G319V	probably damaging	Het
Cyp4f37	G	A	17: 32,629,983 (GRCm38)	R275Q	possibly damaging	Het
Def8	C	T	8: 123,460,070 (GRCm38)		probably benign	Het
Dock6	A	G	9: 21,824,416 (GRCm38)	V1012A	probably benign	Het
Dus3l	T	A	17: 56,769,579 (GRCm38)	N586K	probably damaging	Het
Dyrk2	T	A	10: 118,860,268 (GRCm38)	I362F	probably damaging	Het
Dyx1c1	T	C	9: 72,971,998 (GRCm38)	V356A	probably damaging	Het
Erc2	T	A	14: 27,776,858 (GRCm38)	D230E	probably damaging	Het
Fam102b	A	T	3: 108,980,152 (GRCm38)	S265R	probably benign	Het
Fat1	A	G	8: 45,044,036 (GRCm38)	H4186R	probably benign	Het
Fbxo44	A	G	4: 148,156,595 (GRCm38)	F179S	probably damaging	Het
Fech	A	G	18: 64,478,649 (GRCm38)		probably null	Het
Fer1l5	T	A	1: 36,385,173 (GRCm38)	C289*	probably null	Het
Fhl5	T	A	4: 25,214,756 (GRCm38)	D7V	probably benign	Het
Flvcr1	G	T	1: 191,009,551 (GRCm38)	T514K	probably damaging	Het
Fmo1	A	T	1: 162,839,616 (GRCm38)		probably null	Het
Gabra6	G	A	11: 42,307,441 (GRCm38)	T384M	probably benign	Het
Gli3	A	G	13: 15,548,625 (GRCm38)	Y117C	probably damaging	Het
Gnao1	A	G	8: 93,896,245 (GRCm38)	D59G	probably benign	Het
Gria2	T	C	3: 80,707,249 (GRCm38)	I495V	possibly damaging	Het
Hnf1b	C	A	11: 83,863,985 (GRCm38)	H161Q	probably benign	Het
Itga8	T	A	2: 12,230,208 (GRCm38)	D413V	possibly damaging	Het
Itpr3	A	T	17: 27,110,921 (GRCm38)	Q1563L	possibly damaging	Het
Kctd16	A	G	18: 40,530,829 (GRCm38)	N337S	probably benign	Het
Klra4	C	T	6: 130,053,053 (GRCm38)	V190M	possibly damaging	Het
Krtap4-9	T	A	11: 99,785,636 (GRCm38)		probably benign	Het
L3mbtl1	GGCCG	GG	2: 162,967,336 (GRCm38)		probably benign	Het
Mchr1	T	C	15: 81,237,843 (GRCm38)	F265L	probably damaging	Het
Megf8	T	A	7: 25,326,441 (GRCm38)	Y83*	probably null	Het
Mettl18	A	G	1: 163,997,177 (GRCm38)	M356V	probably null	Het
Mrm1	G	A	11: 84,819,192 (GRCm38)	R61W	probably damaging	Het
Muc4	A	T	16: 32,751,705 (GRCm38)	T528S	probably benign	Het
Myef2	A	T	2: 125,095,731 (GRCm38)	L530*	probably null	Het
Nhlrc4	T	C	17: 25,943,719 (GRCm38)	E18G	probably benign	Het
Nisch	C	T	14: 31,173,145 (GRCm38)	V1065I	probably benign	Het
Nlgn2	C	T	11: 69,834,149 (GRCm38)	R97H	probably damaging	Het
Nos2	T	C	11: 78,937,915 (GRCm38)	L321S	probably damaging	Het
Oaz3	T	C	3: 94,436,410 (GRCm38)	M49V	possibly damaging	Het
Olfm5	A	G	7: 104,154,155 (GRCm38)	V367A	probably damaging	Het
Olfr130	C	A	17: 38,067,750 (GRCm38)	A193D	probably benign	Het
Olfr1335	C	T	4: 118,809,378 (GRCm38)	R162H	probably benign	Het
Olfr564	A	T	7: 102,804,274 (GRCm38)	R265S	probably damaging	Het
Olfr742	C	A	14: 50,515,792 (GRCm38)	A196D	probably benign	Het
Olfr77	A	G	9: 19,920,910 (GRCm38)	K234E	probably damaging	Het
Omd	C	T	13: 49,589,636 (GRCm38)	P54L	possibly damaging	Het
Pard3b	T	A	1: 61,768,130 (GRCm38)		probably benign	Het
Pcdhb18	A	C	18: 37,491,935 (GRCm38)	I773L	possibly damaging	Het
Pde11a	T	C	2: 76,139,831 (GRCm38)		probably null	Het
Pfkfb4	A	C	9: 109,030,394 (GRCm38)		probably benign	Het
Phb2	T	G	6: 124,715,649 (GRCm38)	I260S	probably damaging	Het
Pkd1l1	G	A	11: 8,958,969 (GRCm38)	T345I	unknown	Het
Pla2g6	T	C	15: 79,303,528 (GRCm38)		probably benign	Het
Pou4f2	G	A	8: 78,436,391 (GRCm38)	S5F	unknown	Het
Ppp1r9a	A	T	6: 5,157,002 (GRCm38)		probably null	Het
Pramel5	A	G	4: 144,272,983 (GRCm38)	I178T	probably benign	Het
Prom2	C	T	2: 127,530,133 (GRCm38)	W745*	probably null	Het
Pros1	T	A	16: 62,928,061 (GRCm38)	N632K	probably damaging	Het
Rab4b	A	G	7: 27,174,502 (GRCm38)	I117T	probably benign	Het
Rbm25	T	A	12: 83,677,866 (GRCm38)	H796Q	possibly damaging	Het
Rnf151	A	T	17: 24,718,030 (GRCm38)		probably null	Het
Rps6ka1	A	T	4: 133,871,571 (GRCm38)	L97I	probably damaging	Het
Sergef	T	A	7: 46,443,464 (GRCm38)	T374S	probably benign	Het
Sh3rf3	G	T	10: 59,130,986 (GRCm38)	G717C	probably damaging	Het
Slc29a4	C	T	5: 142,721,402 (GRCm38)	T500I	possibly damaging	Het
Smc1b	T	A	15: 85,086,121 (GRCm38)	D977V	probably damaging	Het
Spata31d1d	C	T	13: 59,727,015 (GRCm38)	C902Y	probably benign	Het
St14	A	T	9: 31,103,760 (GRCm38)	V314D	probably damaging	Het
Stat3	A	T	11: 100,893,670 (GRCm38)	I602N	possibly damaging	Het
Stx4a	T	A	7: 127,846,489 (GRCm38)	I189N	probably damaging	Het
Tacc1	A	G	8: 25,182,199 (GRCm38)	S338P	probably benign	Het
Tcirg1	T	A	19: 3,902,424 (GRCm38)	T315S	possibly damaging	Het
Tenm4	A	T	7: 96,854,719 (GRCm38)	N1295I	probably damaging	Het
Tm7sf3	T	C	6: 146,603,911 (GRCm38)	K516E	possibly damaging	Het
Tmem198b	T	C	10: 128,801,454 (GRCm38)	E272G	possibly damaging	Het
Tnip3	A	G	6: 65,605,953 (GRCm38)	Q237R	probably damaging	Het
Trim15	C	T	17: 36,862,360 (GRCm38)		probably null	Het
Trim30a	T	A	7: 104,421,450 (GRCm38)	N252I	possibly damaging	Het
Ttc39a	A	G	4: 109,430,878 (GRCm38)	E227G	probably benign	Het
Ttll13	A	G	7: 80,253,166 (GRCm38)	E194G	probably damaging	Het
Upf1	G	A	8: 70,344,262 (GRCm38)	T107I	probably benign	Het
Vac14	A	G	8: 110,710,349 (GRCm38)	I565V	probably damaging	Het
Zcchc14	A	T	8: 121,611,358 (GRCm38)		probably benign	Het

Other mutations in Dnah10

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00088:Dnah10	APN	5	124,828,603 (GRCm38)	missense	probably damaging	1.00
IGL00089:Dnah10	APN	5	124,746,616 (GRCm38)	missense	probably benign	0.01
IGL00471:Dnah10	APN	5	124,794,341 (GRCm38)	missense	probably damaging	1.00
IGL01336:Dnah10	APN	5	124,775,512 (GRCm38)	missense	probably damaging	1.00
IGL01339:Dnah10	APN	5	124,777,212 (GRCm38)	missense	probably damaging	1.00
IGL01372:Dnah10	APN	5	124,779,154 (GRCm38)	missense	probably damaging	1.00
IGL01572:Dnah10	APN	5	124,783,946 (GRCm38)	missense	probably damaging	1.00
IGL01634:Dnah10	APN	5	124,821,341 (GRCm38)	missense	probably damaging	0.98
IGL01649:Dnah10	APN	5	124,732,489 (GRCm38)	missense	probably damaging	0.97
IGL01676:Dnah10	APN	5	124,803,328 (GRCm38)	missense	possibly damaging	0.65
IGL01729:Dnah10	APN	5	124,787,465 (GRCm38)	missense	probably benign	0.10
IGL01757:Dnah10	APN	5	124,768,927 (GRCm38)	missense	probably benign	0.37
IGL01759:Dnah10	APN	5	124,755,786 (GRCm38)	missense	probably benign
IGL01767:Dnah10	APN	5	124,743,737 (GRCm38)	splice site	probably benign
IGL01769:Dnah10	APN	5	124,764,944 (GRCm38)	missense	possibly damaging	0.63
IGL01805:Dnah10	APN	5	124,783,921 (GRCm38)	missense	probably damaging	1.00
IGL02090:Dnah10	APN	5	124,789,812 (GRCm38)	missense	probably damaging	1.00
IGL02162:Dnah10	APN	5	124,804,746 (GRCm38)	missense	probably damaging	1.00
IGL02312:Dnah10	APN	5	124,819,366 (GRCm38)	missense	probably damaging	1.00
IGL02347:Dnah10	APN	5	124,833,423 (GRCm38)	critical splice acceptor site	probably null
IGL02378:Dnah10	APN	5	124,773,067 (GRCm38)	missense	probably damaging	1.00
IGL02440:Dnah10	APN	5	124,773,819 (GRCm38)	missense	probably damaging	1.00
IGL02457:Dnah10	APN	5	124,789,796 (GRCm38)	missense	probably damaging	1.00
IGL02487:Dnah10	APN	5	124,793,852 (GRCm38)	missense	possibly damaging	0.90
IGL02502:Dnah10	APN	5	124,821,287 (GRCm38)	missense	probably damaging	1.00
IGL02516:Dnah10	APN	5	124,787,331 (GRCm38)	missense	probably damaging	1.00
IGL02544:Dnah10	APN	5	124,799,005 (GRCm38)	missense	probably benign	0.26
IGL02709:Dnah10	APN	5	124,773,745 (GRCm38)	nonsense	probably null
IGL02740:Dnah10	APN	5	124,826,863 (GRCm38)	splice site	probably benign
IGL02746:Dnah10	APN	5	124,730,086 (GRCm38)	missense	possibly damaging	0.55
IGL02803:Dnah10	APN	5	124,798,014 (GRCm38)	missense	probably damaging	0.99
IGL02900:Dnah10	APN	5	124,801,822 (GRCm38)	missense	probably damaging	1.00
IGL02957:Dnah10	APN	5	124,763,133 (GRCm38)	missense	probably benign	0.07
IGL03076:Dnah10	APN	5	124,730,162 (GRCm38)	critical splice donor site	probably null
IGL03109:Dnah10	APN	5	124,764,886 (GRCm38)	missense	probably benign	0.10
IGL03181:Dnah10	APN	5	124,748,457 (GRCm38)	missense	probably damaging	0.99
IGL03185:Dnah10	APN	5	124,817,643 (GRCm38)	missense	probably damaging	1.00
IGL03199:Dnah10	APN	5	124,817,697 (GRCm38)	missense	probably benign	0.00
IGL03328:Dnah10	APN	5	124,754,290 (GRCm38)	missense	probably benign	0.06
frosty	UTSW	5	124,828,137 (GRCm38)	missense	probably damaging	1.00
H8562:Dnah10	UTSW	5	124,829,529 (GRCm38)	missense	probably damaging	1.00
I2288:Dnah10	UTSW	5	124,730,100 (GRCm38)	missense	probably benign
P0019:Dnah10	UTSW	5	124,763,066 (GRCm38)	missense	probably benign
P0037:Dnah10	UTSW	5	124,817,992 (GRCm38)	nonsense	probably null
PIT4366001:Dnah10	UTSW	5	124,775,524 (GRCm38)	missense	possibly damaging	0.95
R0004:Dnah10	UTSW	5	124,726,902 (GRCm38)	missense	probably benign
R0032:Dnah10	UTSW	5	124,800,891 (GRCm38)	missense	possibly damaging	0.94
R0032:Dnah10	UTSW	5	124,800,891 (GRCm38)	missense	possibly damaging	0.94
R0050:Dnah10	UTSW	5	124,830,744 (GRCm38)	missense	probably benign	0.00
R0066:Dnah10	UTSW	5	124,763,076 (GRCm38)	missense	probably benign	0.01
R0164:Dnah10	UTSW	5	124,783,834 (GRCm38)	missense	probably damaging	1.00
R0164:Dnah10	UTSW	5	124,783,834 (GRCm38)	missense	probably damaging	1.00
R0196:Dnah10	UTSW	5	124,834,075 (GRCm38)	missense	possibly damaging	0.80
R0312:Dnah10	UTSW	5	124,796,369 (GRCm38)	splice site	probably benign
R0321:Dnah10	UTSW	5	124,823,352 (GRCm38)	missense	probably benign	0.29
R0410:Dnah10	UTSW	5	124,755,735 (GRCm38)	missense	probably benign
R0480:Dnah10	UTSW	5	124,808,851 (GRCm38)	missense	probably damaging	1.00
R0531:Dnah10	UTSW	5	124,812,723 (GRCm38)	critical splice donor site	probably null
R0533:Dnah10	UTSW	5	124,775,250 (GRCm38)	splice site	probably null
R0599:Dnah10	UTSW	5	124,800,953 (GRCm38)	missense	probably damaging	1.00
R0686:Dnah10	UTSW	5	124,747,718 (GRCm38)	missense	possibly damaging	0.95
R0688:Dnah10	UTSW	5	124,747,718 (GRCm38)	missense	possibly damaging	0.95
R0780:Dnah10	UTSW	5	124,750,812 (GRCm38)	missense	possibly damaging	0.87
R0968:Dnah10	UTSW	5	124,829,577 (GRCm38)	missense	probably damaging	0.99
R0989:Dnah10	UTSW	5	124,797,938 (GRCm38)	missense	probably benign	0.00
R1203:Dnah10	UTSW	5	124,760,014 (GRCm38)	splice site	probably null
R1248:Dnah10	UTSW	5	124,755,823 (GRCm38)	splice site	probably benign
R1366:Dnah10	UTSW	5	124,753,326 (GRCm38)	missense	probably benign	0.41
R1434:Dnah10	UTSW	5	124,774,986 (GRCm38)	missense	probably benign	0.03
R1436:Dnah10	UTSW	5	124,762,221 (GRCm38)	missense	probably benign	0.00
R1438:Dnah10	UTSW	5	124,798,945 (GRCm38)	missense	probably benign	0.25
R1446:Dnah10	UTSW	5	124,789,796 (GRCm38)	missense	probably damaging	1.00
R1459:Dnah10	UTSW	5	124,743,686 (GRCm38)	missense	possibly damaging	0.90
R1466:Dnah10	UTSW	5	124,763,096 (GRCm38)	missense	probably benign
R1466:Dnah10	UTSW	5	124,763,096 (GRCm38)	missense	probably benign
R1479:Dnah10	UTSW	5	124,777,889 (GRCm38)	missense	possibly damaging	0.71
R1505:Dnah10	UTSW	5	124,754,239 (GRCm38)	missense	possibly damaging	0.82
R1519:Dnah10	UTSW	5	124,760,952 (GRCm38)	missense	probably damaging	0.98
R1565:Dnah10	UTSW	5	124,829,614 (GRCm38)	missense	probably damaging	1.00
R1668:Dnah10	UTSW	5	124,765,562 (GRCm38)	missense	probably benign	0.00
R1709:Dnah10	UTSW	5	124,760,091 (GRCm38)	missense	probably damaging	0.99
R1740:Dnah10	UTSW	5	124,773,190 (GRCm38)	splice site	probably null
R1828:Dnah10	UTSW	5	124,761,279 (GRCm38)	missense	probably benign	0.00
R1854:Dnah10	UTSW	5	124,804,689 (GRCm38)	missense	probably damaging	0.99
R1865:Dnah10	UTSW	5	124,832,526 (GRCm38)	splice site	probably null
R1893:Dnah10	UTSW	5	124,754,317 (GRCm38)	missense	probably benign	0.13
R1895:Dnah10	UTSW	5	124,758,430 (GRCm38)	missense	probably benign	0.00
R1906:Dnah10	UTSW	5	124,800,984 (GRCm38)	missense	probably damaging	1.00
R1953:Dnah10	UTSW	5	124,782,268 (GRCm38)	missense	probably benign	0.00
R1965:Dnah10	UTSW	5	124,775,203 (GRCm38)	missense	probably damaging	1.00
R2002:Dnah10	UTSW	5	124,833,988 (GRCm38)	missense	probably damaging	1.00
R2006:Dnah10	UTSW	5	124,829,587 (GRCm38)	missense	possibly damaging	0.58
R2037:Dnah10	UTSW	5	124,746,704 (GRCm38)	missense	probably benign	0.30
R2046:Dnah10	UTSW	5	124,796,341 (GRCm38)	missense	probably benign	0.25
R2074:Dnah10	UTSW	5	124,814,674 (GRCm38)	missense	probably damaging	1.00
R2081:Dnah10	UTSW	5	124,774,981 (GRCm38)	missense	possibly damaging	0.88
R2257:Dnah10	UTSW	5	124,761,237 (GRCm38)	missense	probably damaging	1.00
R2272:Dnah10	UTSW	5	124,731,466 (GRCm38)	missense	probably benign	0.00
R2293:Dnah10	UTSW	5	124,819,221 (GRCm38)	missense	probably damaging	0.97
R2323:Dnah10	UTSW	5	124,742,000 (GRCm38)	missense	probably damaging	1.00
R2435:Dnah10	UTSW	5	124,762,865 (GRCm38)	critical splice donor site	probably null
R2571:Dnah10	UTSW	5	124,775,478 (GRCm38)	missense	probably damaging	1.00
R2898:Dnah10	UTSW	5	124,817,670 (GRCm38)	missense	probably damaging	1.00
R2937:Dnah10	UTSW	5	124,819,412 (GRCm38)	critical splice donor site	probably null
R3439:Dnah10	UTSW	5	124,796,258 (GRCm38)	missense	possibly damaging	0.91
R3548:Dnah10	UTSW	5	124,747,630 (GRCm38)	missense	possibly damaging	0.50
R3881:Dnah10	UTSW	5	124,773,031 (GRCm38)	missense	probably benign	0.37
R4015:Dnah10	UTSW	5	124,777,926 (GRCm38)	missense	probably benign	0.25
R4261:Dnah10	UTSW	5	124,730,137 (GRCm38)	missense	possibly damaging	0.95
R4277:Dnah10	UTSW	5	124,732,330 (GRCm38)	missense	probably benign	0.28
R4299:Dnah10	UTSW	5	124,819,925 (GRCm38)	missense	probably damaging	1.00
R4613:Dnah10	UTSW	5	124,762,869 (GRCm38)	splice site	probably null
R4651:Dnah10	UTSW	5	124,729,143 (GRCm38)	missense	probably benign	0.20
R4652:Dnah10	UTSW	5	124,729,143 (GRCm38)	missense	probably benign	0.20
R4664:Dnah10	UTSW	5	124,828,472 (GRCm38)	missense	possibly damaging	0.95
R4665:Dnah10	UTSW	5	124,828,472 (GRCm38)	missense	possibly damaging	0.95
R4666:Dnah10	UTSW	5	124,828,472 (GRCm38)	missense	possibly damaging	0.95
R4691:Dnah10	UTSW	5	124,775,517 (GRCm38)	missense	probably damaging	1.00
R4755:Dnah10	UTSW	5	124,747,745 (GRCm38)	missense	probably benign	0.01
R4806:Dnah10	UTSW	5	124,819,344 (GRCm38)	missense	probably damaging	1.00
R4839:Dnah10	UTSW	5	124,773,132 (GRCm38)	missense	probably damaging	1.00
R4903:Dnah10	UTSW	5	124,817,748 (GRCm38)	missense	probably damaging	1.00
R5018:Dnah10	UTSW	5	124,762,196 (GRCm38)	missense	possibly damaging	0.79
R5101:Dnah10	UTSW	5	124,832,513 (GRCm38)	missense	possibly damaging	0.51
R5105:Dnah10	UTSW	5	124,811,482 (GRCm38)	missense	probably benign	0.01
R5119:Dnah10	UTSW	5	124,779,258 (GRCm38)	missense	probably damaging	1.00
R5139:Dnah10	UTSW	5	124,798,960 (GRCm38)	missense	probably damaging	0.99
R5242:Dnah10	UTSW	5	124,787,420 (GRCm38)	missense	probably benign	0.00
R5262:Dnah10	UTSW	5	124,785,156 (GRCm38)	missense	probably damaging	1.00
R5277:Dnah10	UTSW	5	124,828,137 (GRCm38)	missense	probably damaging	1.00
R5293:Dnah10	UTSW	5	124,791,787 (GRCm38)	missense	probably benign	0.01
R5322:Dnah10	UTSW	5	124,773,566 (GRCm38)	missense	probably damaging	1.00
R5371:Dnah10	UTSW	5	124,743,629 (GRCm38)	missense	probably benign	0.16
R5468:Dnah10	UTSW	5	124,830,493 (GRCm38)	missense	probably damaging	1.00
R5470:Dnah10	UTSW	5	124,753,168 (GRCm38)	missense	probably benign
R5587:Dnah10	UTSW	5	124,793,913 (GRCm38)	missense	probably benign	0.10
R5724:Dnah10	UTSW	5	124,742,026 (GRCm38)	missense	probably benign	0.27
R5797:Dnah10	UTSW	5	124,821,386 (GRCm38)	missense	probably benign	0.00
R5812:Dnah10	UTSW	5	124,747,746 (GRCm38)	missense	probably benign	0.01
R5846:Dnah10	UTSW	5	124,823,373 (GRCm38)	missense	possibly damaging	0.80
R5961:Dnah10	UTSW	5	124,811,482 (GRCm38)	missense	probably benign	0.01
R5970:Dnah10	UTSW	5	124,808,729 (GRCm38)	missense	probably benign
R6021:Dnah10	UTSW	5	124,736,984 (GRCm38)	missense	probably damaging	1.00
R6043:Dnah10	UTSW	5	124,801,860 (GRCm38)	missense	probably damaging	1.00
R6073:Dnah10	UTSW	5	124,819,210 (GRCm38)	missense	probably benign	0.09
R6080:Dnah10	UTSW	5	124,805,897 (GRCm38)	missense	possibly damaging	0.71
R6093:Dnah10	UTSW	5	124,753,174 (GRCm38)	missense	probably benign	0.18
R6155:Dnah10	UTSW	5	124,785,175 (GRCm38)	missense	probably damaging	1.00
R6155:Dnah10	UTSW	5	124,770,599 (GRCm38)	missense	probably damaging	1.00
R6162:Dnah10	UTSW	5	124,823,318 (GRCm38)	missense	probably benign	0.02
R6238:Dnah10	UTSW	5	124,743,679 (GRCm38)	missense	probably damaging	0.97
R6248:Dnah10	UTSW	5	124,794,219 (GRCm38)	splice site	probably null
R6275:Dnah10	UTSW	5	124,785,184 (GRCm38)	missense	probably damaging	1.00
R6297:Dnah10	UTSW	5	124,775,080 (GRCm38)	missense	possibly damaging	0.55
R6388:Dnah10	UTSW	5	124,829,646 (GRCm38)	missense	probably benign	0.00
R6458:Dnah10	UTSW	5	124,809,269 (GRCm38)	missense	probably damaging	1.00
R6504:Dnah10	UTSW	5	124,762,782 (GRCm38)	missense	possibly damaging	0.50
R6518:Dnah10	UTSW	5	124,758,355 (GRCm38)	missense	probably damaging	0.99
R6627:Dnah10	UTSW	5	124,830,033 (GRCm38)	missense	probably damaging	1.00
R6701:Dnah10	UTSW	5	124,760,159 (GRCm38)	missense	probably benign	0.45
R6702:Dnah10	UTSW	5	124,805,805 (GRCm38)	missense	probably damaging	1.00
R6745:Dnah10	UTSW	5	124,808,812 (GRCm38)	missense	probably damaging	1.00
R6784:Dnah10	UTSW	5	124,777,826 (GRCm38)	missense	probably damaging	0.99
R6807:Dnah10	UTSW	5	124,790,000 (GRCm38)	splice site	probably null
R6932:Dnah10	UTSW	5	124,821,450 (GRCm38)	missense	possibly damaging	0.75
R7007:Dnah10	UTSW	5	124,787,426 (GRCm38)	missense	probably damaging	1.00
R7091:Dnah10	UTSW	5	124,816,142 (GRCm38)	missense	probably benign	0.37
R7138:Dnah10	UTSW	5	124,822,945 (GRCm38)	missense	probably damaging	1.00
R7144:Dnah10	UTSW	5	124,822,942 (GRCm38)	missense	probably damaging	0.98
R7231:Dnah10	UTSW	5	124,813,828 (GRCm38)	missense	probably benign	0.19
R7278:Dnah10	UTSW	5	124,791,791 (GRCm38)	critical splice donor site	probably null
R7284:Dnah10	UTSW	5	124,832,598 (GRCm38)	missense	probably benign	0.37
R7322:Dnah10	UTSW	5	124,821,269 (GRCm38)	missense	probably benign	0.08
R7523:Dnah10	UTSW	5	124,747,739 (GRCm38)	missense	probably damaging	0.97
R7565:Dnah10	UTSW	5	124,799,031 (GRCm38)	missense	probably damaging	1.00
R7593:Dnah10	UTSW	5	124,746,544 (GRCm38)	missense	probably benign	0.21
R7606:Dnah10	UTSW	5	124,817,712 (GRCm38)	missense	probably benign	0.00
R7835:Dnah10	UTSW	5	124,777,234 (GRCm38)	missense	probably damaging	1.00
R7898:Dnah10	UTSW	5	124,782,361 (GRCm38)	missense	probably damaging	1.00
R7972:Dnah10	UTSW	5	124,726,885 (GRCm38)	missense	probably benign
R7999:Dnah10	UTSW	5	124,725,258 (GRCm38)	missense	probably benign	0.06
R8017:Dnah10	UTSW	5	124,800,885 (GRCm38)	missense	probably benign	0.03
R8032:Dnah10	UTSW	5	124,746,612 (GRCm38)	missense	probably damaging	0.98
R8052:Dnah10	UTSW	5	124,828,511 (GRCm38)	missense	probably benign	0.00
R8088:Dnah10	UTSW	5	124,754,266 (GRCm38)	missense	probably benign	0.00
R8169:Dnah10	UTSW	5	124,800,882 (GRCm38)	missense	probably damaging	1.00
R8178:Dnah10	UTSW	5	124,755,726 (GRCm38)	missense	probably benign	0.11
R8200:Dnah10	UTSW	5	124,828,460 (GRCm38)	missense	probably damaging	1.00
R8210:Dnah10	UTSW	5	124,750,794 (GRCm38)	missense	probably benign	0.29
R8294:Dnah10	UTSW	5	124,782,346 (GRCm38)	missense	probably damaging	1.00
R8338:Dnah10	UTSW	5	124,832,502 (GRCm38)	missense	probably damaging	1.00
R8404:Dnah10	UTSW	5	124,773,542 (GRCm38)	missense	probably damaging	1.00
R8469:Dnah10	UTSW	5	124,736,831 (GRCm38)	missense	probably damaging	1.00
R8537:Dnah10	UTSW	5	124,816,100 (GRCm38)	missense	probably damaging	0.97
R8701:Dnah10	UTSW	5	124,726,847 (GRCm38)	missense	probably benign	0.00
R8723:Dnah10	UTSW	5	124,814,621 (GRCm38)	missense	probably damaging	0.99
R8770:Dnah10	UTSW	5	124,775,346 (GRCm38)	missense	possibly damaging	0.94
R8838:Dnah10	UTSW	5	124,765,550 (GRCm38)	missense	probably benign	0.09
R8879:Dnah10	UTSW	5	124,818,117 (GRCm38)	missense	probably damaging	1.00
R8928:Dnah10	UTSW	5	124,789,764 (GRCm38)	missense	probably damaging	0.98
R8932:Dnah10	UTSW	5	124,800,951 (GRCm38)	missense	possibly damaging	0.96
R8945:Dnah10	UTSW	5	124,813,942 (GRCm38)	missense	probably damaging	0.99
R8990:Dnah10	UTSW	5	124,736,993 (GRCm38)	missense
R9001:Dnah10	UTSW	5	124,775,451 (GRCm38)	missense	probably damaging	1.00
R9006:Dnah10	UTSW	5	124,743,719 (GRCm38)	missense	probably benign	0.23
R9060:Dnah10	UTSW	5	124,828,077 (GRCm38)	missense	probably damaging	1.00
R9085:Dnah10	UTSW	5	124,762,173 (GRCm38)	missense
R9133:Dnah10	UTSW	5	124,782,359 (GRCm38)	missense	probably damaging	1.00
R9155:Dnah10	UTSW	5	124,830,411 (GRCm38)	missense	probably damaging	0.99
R9220:Dnah10	UTSW	5	124,794,373 (GRCm38)	missense	probably benign	0.05
R9234:Dnah10	UTSW	5	124,741,925 (GRCm38)	missense	possibly damaging	0.94
R9264:Dnah10	UTSW	5	124,736,836 (GRCm38)	missense	probably damaging	1.00
R9266:Dnah10	UTSW	5	124,768,926 (GRCm38)	missense	probably benign	0.00
R9386:Dnah10	UTSW	5	124,794,443 (GRCm38)	critical splice donor site	probably null
R9446:Dnah10	UTSW	5	124,746,613 (GRCm38)	missense	probably damaging	1.00
R9484:Dnah10	UTSW	5	124,823,444 (GRCm38)	missense	probably damaging	1.00
R9594:Dnah10	UTSW	5	124,830,043 (GRCm38)	missense	probably damaging	1.00
R9691:Dnah10	UTSW	5	124,775,185 (GRCm38)	missense	probably damaging	0.98
RF015:Dnah10	UTSW	5	124,818,077 (GRCm38)	missense	probably damaging	1.00
RF021:Dnah10	UTSW	5	124,777,907 (GRCm38)	missense	probably damaging	1.00
T0975:Dnah10	UTSW	5	124,763,066 (GRCm38)	missense	probably benign
U24488:Dnah10	UTSW	5	124,813,980 (GRCm38)	missense	probably damaging	1.00
X0017:Dnah10	UTSW	5	124,765,697 (GRCm38)	missense	probably benign	0.22
Z1176:Dnah10	UTSW	5	124,775,355 (GRCm38)	missense	probably benign	0.11
Z1177:Dnah10	UTSW	5	124,741,955 (GRCm38)	missense	probably damaging	1.00
Z1177:Dnah10	UTSW	5	124,817,988 (GRCm38)	critical splice acceptor site	probably null
Z1177:Dnah10	UTSW	5	124,747,619 (GRCm38)	missense	possibly damaging	0.64

Predicted Primers

PCR Primer
(F):5'- CATTCGTGGACCATGTGTTAGC -3'
(R):5'- AGAATGTTTCCTGCTGGCTTC -3'

Sequencing Primer
(F):5'- GTGGACCATGTGTTAGCAACCAC -3'
(R):5'- TGTTGATTCCTGGCCTAAGC -3'

Posted On

2017-02-28