Incidental Mutation 'R5933:Dnah7c'
| ID |
461970 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Dnah7c
|
| Ensembl Gene |
ENSMUSG00000101337 |
| Gene Name |
dynein, axonemal, heavy chain 7C |
| Synonyms |
Dnahc7c |
| MMRRC Submission |
044127-MU
|
| Accession Numbers |
|
| Essential gene? |
Possibly non essential
(E-score: 0.371)
|
| Stock # |
R5933 (G1)
|
| Quality Score |
225 |
|
Status
|
Validated
|
| Chromosome |
1 |
| Chromosomal Location |
46464752-46846636 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
T to C
at 46558375 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Tyrosine to Histidine
at position 494
(Y494H)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000140430
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000189749]
|
| AlphaFold |
no structure available at present |
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000189749
AA Change: Y494H
PolyPhen 2
Score 0.996 (Sensitivity: 0.55; Specificity: 0.98)
|
| SMART Domains |
Protein: ENSMUSP00000140430
Gene: ENSMUSG00000101337
AA Change: Y494H
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
2 |
15 |
N/A |
INTRINSIC |
|
low complexity region
|
37 |
48 |
N/A |
INTRINSIC |
|
coiled coil region
|
714 |
746 |
N/A |
INTRINSIC |
|
Pfam:DHC_N2
|
754 |
1167 |
2.2e-138 |
PFAM |
|
AAA
|
1320 |
1459 |
4e-3 |
SMART |
|
Blast:AAA
|
1601 |
1829 |
4e-87 |
BLAST |
|
AAA
|
1968 |
2116 |
8.7e-4 |
SMART |
|
Pfam:AAA_8
|
2303 |
2574 |
6.2e-73 |
PFAM |
|
Pfam:MT
|
2586 |
2935 |
5.4e-52 |
PFAM |
|
Pfam:AAA_9
|
2953 |
3183 |
7.4e-63 |
PFAM |
|
Pfam:Dynein_heavy
|
3312 |
4021 |
1.3e-250 |
PFAM |
|
| Meta Mutation Damage Score |
0.2614 |
| Coding Region Coverage |
- 1x: 99.9%
- 3x: 99.6%
- 10x: 98.2%
- 20x: 95.1%
|
| Validation Efficiency |
94% (99/105) |
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 93 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 1110002E22Rik |
C |
T |
3: 137,776,109 (GRCm39) |
P1766L |
probably damaging |
Het |
| Abca13 |
A |
G |
11: 9,199,658 (GRCm39) |
Q119R |
possibly damaging |
Het |
| Acot11 |
C |
T |
4: 106,617,327 (GRCm39) |
G240R |
probably damaging |
Het |
| Aipl1 |
A |
C |
11: 71,921,108 (GRCm39) |
C237G |
probably benign |
Het |
| Ankdd1a |
C |
T |
9: 65,416,978 (GRCm39) |
A154T |
probably benign |
Het |
| Arglu1 |
T |
C |
8: 8,740,047 (GRCm39) |
S91G |
probably benign |
Het |
| Arhgef33 |
C |
A |
17: 80,644,709 (GRCm39) |
H13N |
probably benign |
Het |
| Atp1a4 |
A |
G |
1: 172,059,841 (GRCm39) |
I796T |
possibly damaging |
Het |
| Birc6 |
C |
G |
17: 74,906,232 (GRCm39) |
S1374R |
probably damaging |
Het |
| Birc6 |
T |
A |
17: 74,906,233 (GRCm39) |
S72T |
probably damaging |
Het |
| Bmpr1b |
T |
C |
3: 141,577,128 (GRCm39) |
*59W |
probably null |
Het |
| Btbd16 |
A |
T |
7: 130,386,011 (GRCm39) |
Q63L |
probably damaging |
Het |
| Cacna1c |
C |
T |
6: 118,589,541 (GRCm39) |
R1592H |
probably damaging |
Het |
| Caps2 |
G |
A |
10: 112,051,351 (GRCm39) |
E541K |
probably benign |
Het |
| Card9 |
T |
C |
2: 26,242,509 (GRCm39) |
E500G |
probably damaging |
Het |
| Carnmt1 |
T |
C |
19: 18,681,469 (GRCm39) |
V396A |
probably benign |
Het |
| Ccnl1 |
T |
A |
3: 65,855,763 (GRCm39) |
K320M |
probably damaging |
Het |
| Cdh20 |
A |
C |
1: 104,912,396 (GRCm39) |
D550A |
probably damaging |
Het |
| Cdhr1 |
T |
A |
14: 36,811,419 (GRCm39) |
T231S |
probably benign |
Het |
| Cenpe |
T |
C |
3: 134,967,389 (GRCm39) |
V2177A |
probably benign |
Het |
| Cfap69 |
A |
G |
5: 5,690,183 (GRCm39) |
C161R |
probably damaging |
Het |
| Ctsd |
C |
T |
7: 141,930,316 (GRCm39) |
V403I |
probably benign |
Het |
| Cyth1 |
C |
T |
11: 118,076,585 (GRCm39) |
|
probably null |
Het |
| Dazl |
A |
T |
17: 50,594,781 (GRCm39) |
|
probably null |
Het |
| Disp3 |
A |
T |
4: 148,325,770 (GRCm39) |
C1329* |
probably null |
Het |
| Dld |
C |
T |
12: 31,383,982 (GRCm39) |
V374I |
probably benign |
Het |
| Dnttip2 |
T |
A |
3: 122,069,217 (GRCm39) |
M144K |
probably benign |
Het |
| Drc1 |
A |
T |
5: 30,502,873 (GRCm39) |
D132V |
probably damaging |
Het |
| Enpp6 |
A |
G |
8: 47,519,039 (GRCm39) |
D269G |
probably benign |
Het |
| Ephx4 |
T |
A |
5: 107,551,631 (GRCm39) |
|
probably null |
Het |
| Evl |
T |
C |
12: 108,649,516 (GRCm39) |
S345P |
possibly damaging |
Het |
| Fam193a |
A |
T |
5: 34,623,024 (GRCm39) |
D1204V |
probably damaging |
Het |
| Fat2 |
A |
T |
11: 55,174,877 (GRCm39) |
D1945E |
probably damaging |
Het |
| Fat4 |
T |
C |
3: 39,005,524 (GRCm39) |
|
probably null |
Het |
| Fbln7 |
A |
T |
2: 128,719,418 (GRCm39) |
M72L |
probably benign |
Het |
| Flnc |
T |
C |
6: 29,441,105 (GRCm39) |
V353A |
probably damaging |
Het |
| Fry |
T |
C |
5: 150,314,265 (GRCm39) |
|
probably benign |
Het |
| Galnt14 |
A |
T |
17: 73,833,300 (GRCm39) |
C225S |
probably benign |
Het |
| Gapvd1 |
T |
C |
2: 34,574,303 (GRCm39) |
S1265G |
probably benign |
Het |
| Gm13030 |
A |
G |
4: 138,598,515 (GRCm39) |
F136S |
unknown |
Het |
| Gucy1a1 |
T |
C |
3: 82,002,114 (GRCm39) |
H655R |
probably damaging |
Het |
| Hk1 |
A |
G |
10: 62,105,773 (GRCm39) |
L890P |
probably damaging |
Het |
| Igfn1 |
T |
A |
1: 135,898,341 (GRCm39) |
R742* |
probably null |
Het |
| Igkv12-49 |
T |
C |
6: 69,693,553 (GRCm39) |
|
noncoding transcript |
Het |
| Igkv2-109 |
T |
A |
6: 68,279,965 (GRCm39) |
L62Q |
possibly damaging |
Het |
| Itgb3 |
A |
G |
11: 104,528,805 (GRCm39) |
T311A |
possibly damaging |
Het |
| Kl |
A |
G |
5: 150,912,948 (GRCm39) |
E899G |
probably damaging |
Het |
| Kyat3 |
A |
T |
3: 142,429,021 (GRCm39) |
D151V |
probably damaging |
Het |
| Morc2b |
A |
T |
17: 33,357,583 (GRCm39) |
M63K |
possibly damaging |
Het |
| Mtbp |
T |
A |
15: 55,434,723 (GRCm39) |
F298L |
possibly damaging |
Het |
| Mtmr3 |
C |
T |
11: 4,448,951 (GRCm39) |
V272I |
probably benign |
Het |
| Muc4 |
A |
G |
16: 32,574,480 (GRCm39) |
T977A |
probably benign |
Het |
| Nebl |
G |
A |
2: 17,408,998 (GRCm39) |
H367Y |
probably benign |
Het |
| Nop58 |
T |
A |
1: 59,743,824 (GRCm39) |
Y274* |
probably null |
Het |
| Nuak1 |
T |
A |
10: 84,210,666 (GRCm39) |
Q474L |
probably damaging |
Het |
| Obscn |
A |
G |
11: 58,889,331 (GRCm39) |
S7523P |
unknown |
Het |
| Oosp3 |
T |
A |
19: 11,682,753 (GRCm39) |
D140E |
probably benign |
Het |
| Or52z15 |
T |
A |
7: 103,332,680 (GRCm39) |
C242S |
probably damaging |
Het |
| Padi2 |
G |
A |
4: 140,644,952 (GRCm39) |
R62H |
probably benign |
Het |
| Patl1 |
A |
G |
19: 11,917,136 (GRCm39) |
N661S |
probably benign |
Het |
| Pcyox1l |
G |
T |
18: 61,831,544 (GRCm39) |
N238K |
probably benign |
Het |
| Pmch |
A |
G |
10: 87,927,011 (GRCm39) |
T5A |
probably benign |
Het |
| Polr3h |
A |
G |
15: 81,800,835 (GRCm39) |
L169P |
probably damaging |
Het |
| Ptpn4 |
A |
G |
1: 119,615,453 (GRCm39) |
V567A |
probably damaging |
Het |
| Rasgrp2 |
T |
G |
19: 6,452,543 (GRCm39) |
F39V |
probably damaging |
Het |
| Setd1b |
G |
A |
5: 123,296,815 (GRCm39) |
|
probably benign |
Het |
| Sh3glb2 |
A |
T |
2: 30,240,401 (GRCm39) |
|
probably null |
Het |
| Slc46a3 |
A |
T |
5: 147,830,700 (GRCm39) |
N44K |
probably benign |
Het |
| Slc9b1 |
T |
A |
3: 135,099,756 (GRCm39) |
N425K |
probably benign |
Het |
| Slfn14 |
A |
T |
11: 83,170,288 (GRCm39) |
V452E |
probably damaging |
Het |
| Slfn8 |
A |
T |
11: 82,894,161 (GRCm39) |
M826K |
probably benign |
Het |
| Slit3 |
G |
A |
11: 35,520,578 (GRCm39) |
V572M |
probably benign |
Het |
| Smr3a |
C |
A |
5: 88,155,873 (GRCm39) |
|
probably null |
Het |
| Snap29 |
T |
C |
16: 17,224,194 (GRCm39) |
S70P |
probably damaging |
Het |
| Svopl |
T |
A |
6: 37,993,949 (GRCm39) |
|
probably benign |
Het |
| Tbc1d17 |
A |
T |
7: 44,494,761 (GRCm39) |
F186I |
probably damaging |
Het |
| Tgm6 |
T |
C |
2: 129,983,176 (GRCm39) |
V255A |
probably damaging |
Het |
| Tjp1 |
G |
T |
7: 64,952,600 (GRCm39) |
T1498K |
probably benign |
Het |
| Tkfc |
C |
A |
19: 10,574,711 (GRCm39) |
E176D |
probably benign |
Het |
| Tmem102 |
C |
T |
11: 69,694,506 (GRCm39) |
V489I |
probably damaging |
Het |
| Ttn |
A |
G |
2: 76,551,781 (GRCm39) |
V22930A |
probably damaging |
Het |
| Tyms |
A |
T |
5: 30,278,357 (GRCm39) |
|
probably null |
Het |
| Uaca |
T |
A |
9: 60,748,238 (GRCm39) |
D67E |
probably damaging |
Het |
| Unc119b |
G |
A |
5: 115,265,508 (GRCm39) |
|
probably benign |
Het |
| Usp29 |
A |
T |
7: 6,964,744 (GRCm39) |
T196S |
probably benign |
Het |
| Usp37 |
A |
G |
1: 74,525,141 (GRCm39) |
S228P |
probably damaging |
Het |
| Usp42 |
C |
A |
5: 143,701,270 (GRCm39) |
A918S |
probably benign |
Het |
| Vmn2r72 |
T |
A |
7: 85,387,058 (GRCm39) |
L835F |
probably benign |
Het |
| Vps13a |
T |
C |
19: 16,637,894 (GRCm39) |
T2396A |
probably benign |
Het |
| Whrn |
A |
T |
4: 63,412,945 (GRCm39) |
S176T |
probably damaging |
Het |
| Zbtb42 |
T |
C |
12: 112,647,055 (GRCm39) |
F410S |
probably damaging |
Het |
| Zfp616 |
T |
C |
11: 73,973,952 (GRCm39) |
S74P |
probably damaging |
Het |
| Zswim6 |
A |
G |
13: 107,880,642 (GRCm39) |
|
noncoding transcript |
Het |
|
| Other mutations in Dnah7c |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00559:Dnah7c
|
APN |
1 |
46,846,449 (GRCm39) |
missense |
possibly damaging |
0.72 |
|
IGL02958:Dnah7c
|
APN |
1 |
46,696,271 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03035:Dnah7c
|
APN |
1 |
46,563,277 (GRCm39) |
missense |
probably benign |
0.37 |
|
IGL03161:Dnah7c
|
APN |
1 |
46,506,456 (GRCm39) |
missense |
probably benign |
0.20 |
|
IGL03178:Dnah7c
|
APN |
1 |
46,506,525 (GRCm39) |
missense |
probably benign |
|
|
IGL03052:Dnah7c
|
UTSW |
1 |
46,671,309 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0751:Dnah7c
|
UTSW |
1 |
46,505,065 (GRCm39) |
missense |
probably benign |
|
|
R1029:Dnah7c
|
UTSW |
1 |
46,651,881 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3104:Dnah7c
|
UTSW |
1 |
46,837,439 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R3977:Dnah7c
|
UTSW |
1 |
46,668,071 (GRCm39) |
missense |
possibly damaging |
0.75 |
|
R4003:Dnah7c
|
UTSW |
1 |
46,720,977 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4133:Dnah7c
|
UTSW |
1 |
46,705,150 (GRCm39) |
missense |
probably benign |
0.01 |
|
R4303:Dnah7c
|
UTSW |
1 |
46,787,738 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4329:Dnah7c
|
UTSW |
1 |
46,688,441 (GRCm39) |
missense |
probably benign |
0.33 |
|
R4434:Dnah7c
|
UTSW |
1 |
46,705,442 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4457:Dnah7c
|
UTSW |
1 |
46,779,781 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4470:Dnah7c
|
UTSW |
1 |
46,787,795 (GRCm39) |
missense |
possibly damaging |
0.56 |
|
R4507:Dnah7c
|
UTSW |
1 |
46,805,771 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4527:Dnah7c
|
UTSW |
1 |
46,572,091 (GRCm39) |
missense |
probably benign |
0.34 |
|
R4571:Dnah7c
|
UTSW |
1 |
46,572,376 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R4589:Dnah7c
|
UTSW |
1 |
46,553,743 (GRCm39) |
nonsense |
probably null |
|
|
R4731:Dnah7c
|
UTSW |
1 |
46,809,333 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4732:Dnah7c
|
UTSW |
1 |
46,809,333 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4733:Dnah7c
|
UTSW |
1 |
46,809,333 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4747:Dnah7c
|
UTSW |
1 |
46,572,328 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4845:Dnah7c
|
UTSW |
1 |
46,832,692 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4873:Dnah7c
|
UTSW |
1 |
46,728,085 (GRCm39) |
missense |
probably benign |
|
|
R4875:Dnah7c
|
UTSW |
1 |
46,728,085 (GRCm39) |
missense |
probably benign |
|
|
R4916:Dnah7c
|
UTSW |
1 |
46,634,168 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5241:Dnah7c
|
UTSW |
1 |
46,569,660 (GRCm39) |
missense |
probably benign |
|
|
R5279:Dnah7c
|
UTSW |
1 |
46,558,429 (GRCm39) |
missense |
probably benign |
0.14 |
|
R5327:Dnah7c
|
UTSW |
1 |
46,704,728 (GRCm39) |
missense |
probably benign |
0.05 |
|
R5546:Dnah7c
|
UTSW |
1 |
46,705,477 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5605:Dnah7c
|
UTSW |
1 |
46,837,395 (GRCm39) |
missense |
possibly damaging |
0.84 |
|
R5637:Dnah7c
|
UTSW |
1 |
46,799,521 (GRCm39) |
splice site |
probably null |
|
|
R5639:Dnah7c
|
UTSW |
1 |
46,778,828 (GRCm39) |
missense |
probably benign |
|
|
R5663:Dnah7c
|
UTSW |
1 |
46,574,308 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5718:Dnah7c
|
UTSW |
1 |
46,787,826 (GRCm39) |
missense |
possibly damaging |
0.47 |
|
R5759:Dnah7c
|
UTSW |
1 |
46,654,527 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5771:Dnah7c
|
UTSW |
1 |
46,678,825 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5784:Dnah7c
|
UTSW |
1 |
46,563,228 (GRCm39) |
missense |
possibly damaging |
0.80 |
|
R5800:Dnah7c
|
UTSW |
1 |
46,686,175 (GRCm39) |
missense |
probably benign |
0.01 |
|
R5948:Dnah7c
|
UTSW |
1 |
46,711,657 (GRCm39) |
missense |
probably benign |
0.21 |
|
R6034:Dnah7c
|
UTSW |
1 |
46,496,418 (GRCm39) |
missense |
probably benign |
0.00 |
|
R6034:Dnah7c
|
UTSW |
1 |
46,496,418 (GRCm39) |
missense |
probably benign |
0.00 |
|
R6487:Dnah7c
|
UTSW |
1 |
46,808,284 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6536:Dnah7c
|
UTSW |
1 |
46,697,450 (GRCm39) |
missense |
probably benign |
0.00 |
|
R6614:Dnah7c
|
UTSW |
1 |
46,688,511 (GRCm39) |
missense |
probably benign |
|
|
R6614:Dnah7c
|
UTSW |
1 |
46,688,500 (GRCm39) |
missense |
probably benign |
|
|
R6615:Dnah7c
|
UTSW |
1 |
46,688,511 (GRCm39) |
missense |
probably benign |
|
|
R6615:Dnah7c
|
UTSW |
1 |
46,554,599 (GRCm39) |
missense |
probably benign |
0.01 |
|
R6615:Dnah7c
|
UTSW |
1 |
46,688,500 (GRCm39) |
missense |
probably benign |
|
|
R6649:Dnah7c
|
UTSW |
1 |
46,688,511 (GRCm39) |
missense |
probably benign |
|
|
R6649:Dnah7c
|
UTSW |
1 |
46,688,500 (GRCm39) |
missense |
probably benign |
|
|
R6650:Dnah7c
|
UTSW |
1 |
46,688,511 (GRCm39) |
missense |
probably benign |
|
|
R6650:Dnah7c
|
UTSW |
1 |
46,688,500 (GRCm39) |
missense |
probably benign |
|
|
R6651:Dnah7c
|
UTSW |
1 |
46,688,511 (GRCm39) |
missense |
probably benign |
|
|
R6651:Dnah7c
|
UTSW |
1 |
46,688,500 (GRCm39) |
missense |
probably benign |
|
|
R6653:Dnah7c
|
UTSW |
1 |
46,688,511 (GRCm39) |
missense |
probably benign |
|
|
R6653:Dnah7c
|
UTSW |
1 |
46,688,500 (GRCm39) |
missense |
probably benign |
|
|
R6714:Dnah7c
|
UTSW |
1 |
46,779,966 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R6729:Dnah7c
|
UTSW |
1 |
46,711,681 (GRCm39) |
missense |
possibly damaging |
0.46 |
|
R6760:Dnah7c
|
UTSW |
1 |
46,688,511 (GRCm39) |
missense |
probably benign |
|
|
R6760:Dnah7c
|
UTSW |
1 |
46,688,500 (GRCm39) |
missense |
probably benign |
|
|
R6763:Dnah7c
|
UTSW |
1 |
46,668,050 (GRCm39) |
missense |
possibly damaging |
0.60 |
|
R6866:Dnah7c
|
UTSW |
1 |
46,696,403 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6880:Dnah7c
|
UTSW |
1 |
46,566,831 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R6988:Dnah7c
|
UTSW |
1 |
46,705,373 (GRCm39) |
missense |
possibly damaging |
0.68 |
|
R6995:Dnah7c
|
UTSW |
1 |
46,494,973 (GRCm39) |
missense |
probably benign |
0.07 |
|
R7007:Dnah7c
|
UTSW |
1 |
46,571,910 (GRCm39) |
missense |
probably benign |
0.04 |
|
R7086:Dnah7c
|
UTSW |
1 |
46,789,285 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7128:Dnah7c
|
UTSW |
1 |
46,566,645 (GRCm39) |
missense |
probably benign |
|
|
R7131:Dnah7c
|
UTSW |
1 |
46,720,932 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7135:Dnah7c
|
UTSW |
1 |
46,572,368 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7171:Dnah7c
|
UTSW |
1 |
46,719,898 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7176:Dnah7c
|
UTSW |
1 |
46,469,969 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7221:Dnah7c
|
UTSW |
1 |
46,494,937 (GRCm39) |
missense |
possibly damaging |
0.87 |
|
R7310:Dnah7c
|
UTSW |
1 |
46,636,127 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R7319:Dnah7c
|
UTSW |
1 |
46,819,935 (GRCm39) |
missense |
probably benign |
0.31 |
|
R7319:Dnah7c
|
UTSW |
1 |
46,823,608 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R7404:Dnah7c
|
UTSW |
1 |
46,705,223 (GRCm39) |
missense |
possibly damaging |
0.52 |
|
R7452:Dnah7c
|
UTSW |
1 |
46,686,196 (GRCm39) |
missense |
possibly damaging |
0.91 |
|
R7515:Dnah7c
|
UTSW |
1 |
46,496,450 (GRCm39) |
missense |
probably benign |
|
|
R7534:Dnah7c
|
UTSW |
1 |
46,809,227 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R7542:Dnah7c
|
UTSW |
1 |
46,823,658 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7605:Dnah7c
|
UTSW |
1 |
46,671,470 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7643:Dnah7c
|
UTSW |
1 |
46,641,973 (GRCm39) |
missense |
probably benign |
|
|
R7770:Dnah7c
|
UTSW |
1 |
46,665,460 (GRCm39) |
splice site |
probably null |
|
|
R7884:Dnah7c
|
UTSW |
1 |
46,830,929 (GRCm39) |
missense |
probably benign |
0.23 |
|
R7899:Dnah7c
|
UTSW |
1 |
46,553,861 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8025:Dnah7c
|
UTSW |
1 |
46,496,456 (GRCm39) |
missense |
probably benign |
0.01 |
|
R8057:Dnah7c
|
UTSW |
1 |
46,728,112 (GRCm39) |
missense |
possibly damaging |
0.52 |
|
R8191:Dnah7c
|
UTSW |
1 |
46,646,618 (GRCm39) |
missense |
possibly damaging |
0.56 |
|
R8255:Dnah7c
|
UTSW |
1 |
46,698,589 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8428:Dnah7c
|
UTSW |
1 |
46,711,536 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8441:Dnah7c
|
UTSW |
1 |
46,572,398 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8485:Dnah7c
|
UTSW |
1 |
46,719,952 (GRCm39) |
missense |
probably benign |
0.05 |
|
R8559:Dnah7c
|
UTSW |
1 |
46,764,299 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8752:Dnah7c
|
UTSW |
1 |
46,711,701 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8869:Dnah7c
|
UTSW |
1 |
46,671,504 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R9058:Dnah7c
|
UTSW |
1 |
46,805,816 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R9121:Dnah7c
|
UTSW |
1 |
46,816,896 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9121:Dnah7c
|
UTSW |
1 |
46,704,650 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R9246:Dnah7c
|
UTSW |
1 |
46,571,934 (GRCm39) |
missense |
possibly damaging |
0.51 |
|
R9319:Dnah7c
|
UTSW |
1 |
46,521,168 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R9388:Dnah7c
|
UTSW |
1 |
46,779,886 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Z1176:Dnah7c
|
UTSW |
1 |
46,654,441 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Z1176:Dnah7c
|
UTSW |
1 |
46,506,462 (GRCm39) |
missense |
probably benign |
0.00 |
|
Z1176:Dnah7c
|
UTSW |
1 |
46,799,476 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
Z1176:Dnah7c
|
UTSW |
1 |
46,686,152 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
Z1176:Dnah7c
|
UTSW |
1 |
46,678,825 (GRCm39) |
missense |
probably benign |
|
|
Z1177:Dnah7c
|
UTSW |
1 |
46,693,263 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
| Predicted Primers |
PCR Primer
(F):5'- GTAAGATTGACACTTTCCGGGAG -3'
(R):5'- AGACAGACCATTCTCTTCCATCAAG -3'
Sequencing Primer
(F):5'- CACTTTCCGGGAGATAATATAGTAGG -3'
(R):5'- CTTCCATCAAGAGTCATAGAGAAAGG -3'
|
| Posted On |
2017-02-28 |
Incidental Mutation