Incidental Mutation 'R0574:2700099C18Rik'
ID46592
Institutional Source Beutler Lab
Gene Symbol 2700099C18Rik
Ensembl Gene ENSMUSG00000098090
Gene NameRIKEN cDNA 2700099C18 gene
Synonyms
MMRRC Submission 038764-MU
Accession Numbers
Is this an essential gene? Possibly non essential (E-score: 0.288) question?
Stock #R0574 (G1)
Quality Score225
Status Validated
Chromosome17
Chromosomal Location94750100-94775132 bp(+) (GRCm38)
Type of Mutationsplice site
DNA Base Change (assembly) T to C at 94761491 bp
ZygosityHeterozygous
Amino Acid Change
Gene Model predicted gene model for transcript(s):
Predicted Effect noncoding transcript
Transcript: ENSMUST00000084298
SMART Domains Protein: ENSMUSP00000081321
Gene: ENSMUSG00000066057

DomainStartEndE-ValueType
low complexity region 25 48 N/A INTRINSIC
transmembrane domain 90 112 N/A INTRINSIC
Predicted Effect noncoding transcript
Transcript: ENSMUST00000157966
Predicted Effect noncoding transcript
Transcript: ENSMUST00000182313
Predicted Effect noncoding transcript
Transcript: ENSMUST00000182402
Predicted Effect noncoding transcript
Transcript: ENSMUST00000182475
Predicted Effect noncoding transcript
Transcript: ENSMUST00000182639
Predicted Effect noncoding transcript
Transcript: ENSMUST00000182794
Predicted Effect noncoding transcript
Transcript: ENSMUST00000183133
Meta Mutation Damage Score 0.0869 question?
Coding Region Coverage
  • 1x: 99.1%
  • 3x: 98.3%
  • 10x: 96.2%
  • 20x: 92.4%
Validation Efficiency 100% (34/34)
Allele List at MGI
Other mutations in this stock
Total: 32 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
Abca14 A G 7: 120,224,497 I416V probably damaging Het
Actrt3 T C 3: 30,599,680 E57G probably benign Het
Adamts5 A G 16: 85,899,484 S262P probably damaging Het
Aldh1a2 T C 9: 71,281,708 probably null Het
Arhgap29 A G 3: 122,007,625 I670V probably benign Het
Bptf T C 11: 107,076,527 D1009G probably damaging Het
Ddr2 G T 1: 169,981,963 probably benign Het
Ift140 T A 17: 25,051,760 probably null Het
Itga1 A C 13: 114,966,561 S1111R probably damaging Het
Klk1b27 T A 7: 44,056,101 L199Q probably damaging Het
Lhx3 T C 2: 26,201,311 S329G probably benign Het
Man2b1 T G 8: 85,096,776 M913R probably benign Het
Mmp15 G A 8: 95,365,401 A80T possibly damaging Het
Mpo A T 11: 87,796,076 Y177F probably damaging Het
Mynn T C 3: 30,616,739 S587P probably benign Het
Nfkbib C T 7: 28,761,788 V145I probably benign Het
Olfr421-ps1 T C 1: 174,151,566 F17L probably benign Het
Olfr727 A T 14: 50,126,682 Y35F probably damaging Het
Olfr98 G T 17: 37,262,881 S261Y probably damaging Het
Pole2 G A 12: 69,211,457 probably benign Het
Ppargc1b C T 18: 61,302,739 G906D probably benign Het
Prl8a2 T A 13: 27,348,900 C32S probably damaging Het
Rhno1 A T 6: 128,358,150 probably null Het
Rprd2 T C 3: 95,774,357 E408G possibly damaging Het
Ryr2 T A 13: 11,731,669 H1999L probably benign Het
Shprh T C 10: 11,163,077 probably benign Het
Snx3 T A 10: 42,502,387 N19K probably benign Het
Stx8 C T 11: 67,973,252 T46M probably damaging Het
Tbc1d17 A G 7: 44,843,123 probably benign Het
Ush1c A G 7: 46,196,804 S855P possibly damaging Het
Usp54 A G 14: 20,556,254 V1338A probably benign Het
Vmn1r214 A G 13: 23,034,493 I52M probably benign Het
Predicted Primers PCR Primer
(F):5'- AGAAAACCTTGGCCTCGGGAAC -3'
(R):5'- ACGAGCCTAAAGAGCTGTCCAGTG -3'

Sequencing Primer
(F):5'- GGCCTCGGGAACTCATATTC -3'
(R):5'- GAGCTGTCCAGTGATTTCAGAAAC -3'
Posted On2013-06-11