Mutagenetix > Incidental Mutation

Incidental Mutation 'R4732:Dnhd1'

470491

Institutional Source

Beutler Lab

Gene Symbol

Dnhd1

Ensembl Gene

ENSMUSG00000030882

Gene Name

dynein heavy chain domain 1

Synonyms

8030491N06Rik

MMRRC Submission

042022-MU

Accession Numbers

Essential gene?

Probably non essential (E-score: 0.077) question?

Stock #

R4732 (G1)

Quality Score

225

Status

Not validated

Chromosome

Chromosomal Location

105650827-105721799 bp(+) (GRCm38)

Type of Mutation

missense

DNA Base Change (assembly)

C to A at 105673849 bp (GRCm38)

Zygosity

Heterozygous

Amino Acid Change

Asparagine to Lysine at position 521 (N521K)

Ref Sequence

ENSEMBL: ENSMUSP00000121261 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000106776] [ENSMUST00000142874] [ENSMUST00000145988] [ENSMUST00000210312]

AlphaFold

no structure available at present

Predicted Effect

probably benign
Transcript: ENSMUST00000106776

SMART Domains

Protein: ENSMUSP00000102388
Gene: ENSMUSG00000030882

Domain	Start	End	E-Value	Type
low complexity region	205	224	N/A	INTRINSIC

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000128388

Predicted Effect

probably benign
Transcript: ENSMUST00000142874

Predicted Effect

probably benign
Transcript: ENSMUST00000145988
AA Change: N521K

PolyPhen 2 Score 0.002 (Sensitivity: 0.99; Specificity: 0.30)

SMART Domains

Protein: ENSMUSP00000121261
Gene: ENSMUSG00000030882
AA Change: N521K

Domain	Start	End	E-Value	Type
low complexity region	5	18	N/A	INTRINSIC
low complexity region	102	115	N/A	INTRINSIC
low complexity region	183	191	N/A	INTRINSIC
low complexity region	253	269	N/A	INTRINSIC
low complexity region	943	962	N/A	INTRINSIC
Pfam:DHC_N2	1018	1472	4.6e-50	PFAM
Pfam:AAA_6	1652	1875	2.7e-14	PFAM
low complexity region	1906	1918	N/A	INTRINSIC
Blast:AAA	1993	2196	1e-34	BLAST
Pfam:AAA_7	2362	2610	3.3e-11	PFAM
low complexity region	2697	2714	N/A	INTRINSIC
low complexity region	2722	2733	N/A	INTRINSIC
low complexity region	2800	2810	N/A	INTRINSIC
low complexity region	3116	3134	N/A	INTRINSIC
Pfam:MT	3178	3470	3.9e-16	PFAM
coiled coil region	3590	3642	N/A	INTRINSIC
coiled coil region	3816	3843	N/A	INTRINSIC
Pfam:Dynein_heavy	3976	4746	7.3e-97	PFAM

Predicted Effect

probably benign
Transcript: ENSMUST00000210312

Meta Mutation Damage Score

0.0898

Coding Region Coverage

1x: 99.3%
3x: 98.7%
10x: 97.2%
20x: 95.1%

Validation Efficiency

99% (110/111)

Allele List at MGI

All alleles(1) : Gene trapped(1)

Other mutations in this stock

Total: 192 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
1700128F08Rik	T	A	9: 8,222,173 (GRCm38)		noncoding transcript	Het
4933409G03Rik	A	G	2: 68,614,721 (GRCm38)		probably benign	Het
Acan	T	C	7: 79,098,609 (GRCm38)	S1043P	probably damaging	Het
Ackr2	A	G	9: 121,909,183 (GRCm38)	Y208C	probably damaging	Het
Actg1	C	T	11: 120,347,479 (GRCm38)		probably benign	Het
Actmap	T	A	7: 27,201,043 (GRCm38)	M149K	probably damaging	Het
Adam1a	T	A	5: 121,519,434 (GRCm38)	T599S	probably benign	Het
Adamts12	A	T	15: 11,270,662 (GRCm38)	S668C	probably damaging	Het
Adcy8	A	G	15: 64,754,862 (GRCm38)	V709A	possibly damaging	Het
Adgrf2	A	C	17: 42,710,754 (GRCm38)	I393S	probably damaging	Het
Ahnak	G	T	19: 9,007,301 (GRCm38)	G1983V	probably damaging	Het
Aim2	T	A	1: 173,463,876 (GRCm38)	D282E	possibly damaging	Het
Ak8	A	G	2: 28,760,071 (GRCm38)	Y370C	probably damaging	Het
Akap9	A	G	5: 4,013,901 (GRCm38)	D1750G	probably damaging	Het
Als2cl	T	A	9: 110,889,136 (GRCm38)	V315E	probably damaging	Het
Ankrd28	A	C	14: 31,755,741 (GRCm38)	C115G	probably benign	Het
Ap3b2	C	T	7: 81,471,932 (GRCm38)	A519T	probably damaging	Het
Apool	C	T	X: 112,372,200 (GRCm38)	T166I	probably damaging	Het
Arhgef2	A	T	3: 88,631,940 (GRCm38)	K65*	probably null	Het
Arhgef38	G	T	3: 133,132,269 (GRCm38)	Y633*	probably null	Het
Asah2	T	C	19: 31,995,358 (GRCm38)	N659S	probably benign	Het
Atf7ip2	A	G	16: 10,241,886 (GRCm38)	D430G	possibly damaging	Het
Atp8a1	G	A	5: 67,813,120 (GRCm38)	S92L	probably benign	Het
Bag4	C	T	8: 25,769,488 (GRCm38)	A228T	probably benign	Het
C130073F10Rik	C	A	4: 101,890,710 (GRCm38)	S89I	probably benign	Het
Cacna1g	T	C	11: 94,443,215 (GRCm38)	T867A	probably damaging	Het
Ccdc88a	T	G	11: 29,485,906 (GRCm38)	N1276K	probably benign	Het
Cdc42bpg	T	A	19: 6,311,191 (GRCm38)	V282E	probably damaging	Het
Cdipt	T	A	7: 126,978,358 (GRCm38)	L92H	probably damaging	Het
Celsr2	T	A	3: 108,398,952 (GRCm38)	D2012V	probably damaging	Het
Cenpt	A	G	8: 105,847,136 (GRCm38)	V254A	probably benign	Het
Cep104	T	A	4: 153,988,426 (GRCm38)	D380E	probably damaging	Het
Cers5	C	T	15: 99,741,637 (GRCm38)	R123Q	probably benign	Het
Ces2h	A	G	8: 105,014,604 (GRCm38)	E76G	probably damaging	Het
Cfap77	T	A	2: 28,984,388 (GRCm38)	E143D	probably benign	Het
Chmp7	C	A	14: 69,732,296 (GRCm38)	R65L	probably damaging	Het
Cldnd2	T	A	7: 43,442,189 (GRCm38)	C65S	possibly damaging	Het
Clec2g	C	A	6: 128,981,879 (GRCm38)	Y142*	probably null	Het
Coch	A	T	12: 51,605,019 (GRCm38)	E549V	probably benign	Het
Cog7	T	C	7: 121,964,244 (GRCm38)	D215G	probably benign	Het
Col4a2	A	G	8: 11,446,197 (GRCm38)	H1606R	probably benign	Het
Col4a2	T	C	8: 11,414,779 (GRCm38)	V348A	probably benign	Het
Cpd	T	C	11: 76,811,794 (GRCm38)	N583D	probably damaging	Het
Cyp2d11	T	A	15: 82,389,227 (GRCm38)	Y481F	probably benign	Het
D130043K22Rik	T	C	13: 24,899,665 (GRCm38)	S1038P	probably damaging	Het
Deptor	C	A	15: 55,181,010 (GRCm38)	H191N	probably benign	Het
Dgkz	A	T	2: 91,938,339 (GRCm38)	I699N	probably damaging	Het
Dnah12	C	T	14: 26,781,784 (GRCm38)	T1653I	probably damaging	Het
Dnah7c	T	A	1: 46,770,173 (GRCm38)	N3550K	probably damaging	Het
Dnah8	A	G	17: 30,775,061 (GRCm38)	K3384R	probably null	Het
Dnajc11	A	G	4: 151,970,967 (GRCm38)		probably benign	Het
Dnajc13	CT	C	9: 104,186,805 (GRCm38)		probably benign	Het
Drg2	T	C	11: 60,461,396 (GRCm38)		probably null	Het
Dync1h1	C	T	12: 110,649,507 (GRCm38)	Q3030*	probably null	Het
Efhb	G	A	17: 53,426,244 (GRCm38)	T533I	probably damaging	Het
Eif2d	T	C	1: 131,164,727 (GRCm38)	V374A	probably damaging	Het
Etfb	T	C	7: 43,444,200 (GRCm38)	V17A	probably damaging	Het
F5	C	T	1: 164,181,657 (GRCm38)	T332M	probably damaging	Het
Fcho1	T	C	8: 71,716,795 (GRCm38)	T156A	probably benign	Het
Fn1	A	T	1: 71,602,512 (GRCm38)		probably null	Het
Fnip2	A	T	3: 79,481,652 (GRCm38)	S561T	probably damaging	Het
Frs2	T	A	10: 117,074,093 (GRCm38)	T455S	probably benign	Het
Fry	G	A	5: 150,386,007 (GRCm38)	E639K		Het
Fto	T	A	8: 91,409,714 (GRCm38)	D205E	probably damaging	Het
Galnt2l	A	G	8: 122,270,274 (GRCm38)		probably benign	Het
Galntl6	G	A	8: 58,427,813 (GRCm38)	P147L	probably damaging	Het
Gigyf1	T	A	5: 137,524,770 (GRCm38)	D844E	probably benign	Het
Gle1	T	C	2: 29,940,232 (GRCm38)	S267P	probably damaging	Het
Glg1	G	A	8: 111,187,755 (GRCm38)	R466W	probably damaging	Het
Gm10277	T	C	11: 77,786,097 (GRCm38)		probably benign	Het
Gm6871	T	C	7: 41,546,749 (GRCm38)	I39V	probably benign	Het
Gm9970	A	G	5: 31,241,066 (GRCm38)		probably benign	Het
Gpr35	T	G	1: 92,983,385 (GRCm38)	I57S	probably damaging	Het
Gprin1	C	T	13: 54,739,957 (GRCm38)	G168E	possibly damaging	Het
Gtdc1	A	G	2: 44,789,055 (GRCm38)		probably benign	Het
Gtf3c2	G	T	5: 31,160,057 (GRCm38)	P586T	probably damaging	Het
Gucy1a2	A	T	9: 3,759,424 (GRCm38)	H410L	probably benign	Het
Gucy2c	A	G	6: 136,767,152 (GRCm38)	S150P	probably damaging	Het
Ifi214	T	C	1: 173,526,591 (GRCm38)	Q171R	probably benign	Het
Ifit1bl1	T	C	19: 34,594,321 (GRCm38)	I245M	probably benign	Het
Igkv4-50	T	C	6: 69,701,000 (GRCm38)	K40R	probably benign	Het
Igkv8-18	T	A	6: 70,356,296 (GRCm38)	I74N	probably damaging	Het
Il2ra	T	A	2: 11,676,920 (GRCm38)	M112K	probably benign	Het
Itpr2	A	G	6: 146,373,173 (GRCm38)	F837S	probably damaging	Het
Kbtbd7	T	C	14: 79,428,800 (GRCm38)	*691Q	probably null	Het
Kcnn2	T	A	18: 45,560,349 (GRCm38)	S331T	possibly damaging	Het
Khnyn	T	A	14: 55,886,489 (GRCm38)		probably null	Het
Kif26a	G	A	12: 112,175,573 (GRCm38)	A754T	probably benign	Het
Klra3	T	A	6: 130,327,132 (GRCm38)	Y199F	possibly damaging	Het
Lhx2	A	G	2: 38,359,991 (GRCm38)	K274R	probably damaging	Het
Lrp2	T	C	2: 69,533,555 (GRCm38)	I313V	probably benign	Het
Lrrfip1	A	T	1: 91,115,647 (GRCm38)	E591D	probably benign	Het
Lrrk2	A	C	15: 91,688,849 (GRCm38)	E200A	probably damaging	Het
Lrrk2	G	A	15: 91,765,747 (GRCm38)	E1696K	probably damaging	Het
Mast4	A	T	13: 102,772,572 (GRCm38)	M465K	probably damaging	Het
Moxd2	T	G	6: 40,878,859 (GRCm38)	I599L	probably benign	Het
Mug2	T	C	6: 122,071,872 (GRCm38)	S866P	probably damaging	Het
Ncam2	A	G	16: 81,434,884 (GRCm38)	T79A	possibly damaging	Het
Ncoa6	C	A	2: 155,421,301 (GRCm38)	Q404H	probably damaging	Het
Neb	A	G	2: 52,279,079 (GRCm38)	Y1815H	probably damaging	Het
Nell1	A	G	7: 50,856,217 (GRCm38)	D724G	probably damaging	Het
Nkx3-2	A	G	5: 41,762,144 (GRCm38)	V167A	probably benign	Het
Nsun3	C	A	16: 62,735,119 (GRCm38)	C348F	possibly damaging	Het
Obox6	A	T	7: 15,834,772 (GRCm38)	S60T	possibly damaging	Het
Oog2	T	A	4: 144,193,941 (GRCm38)		probably benign	Het
Or10g9b	A	T	9: 40,006,268 (GRCm38)	I227N	probably damaging	Het
Or11g2	T	A	14: 50,618,569 (GRCm38)	C116S	probably benign	Het
Or1ad6	G	A	11: 50,969,266 (GRCm38)	V83M	possibly damaging	Het
Or1e16	T	C	11: 73,395,695 (GRCm38)	D109G	probably benign	Het
Or2i1	T	C	17: 37,197,024 (GRCm38)	T315A	probably damaging	Het
Or2n1e	T	A	17: 38,275,547 (GRCm38)	Y259N	probably damaging	Het
Or9s18	T	C	13: 65,152,653 (GRCm38)	V143A	possibly damaging	Het
Pabpc1	A	T	15: 36,599,284 (GRCm38)	V389E	probably benign	Het
Pank4	A	T	4: 154,971,390 (GRCm38)	M291L	probably benign	Het
Pcf11	T	C	7: 92,658,833 (GRCm38)	D709G	probably benign	Het
Pcgf1	T	A	6: 83,079,957 (GRCm38)		probably benign	Het
Pcnx1	A	G	12: 81,995,751 (GRCm38)	I2256V	probably benign	Het
Pex6	A	G	17: 46,724,707 (GRCm38)		probably null	Het
Pex6	A	G	17: 46,722,288 (GRCm38)	D579G	probably benign	Het
Piezo2	C	T	18: 63,030,401 (GRCm38)	A2149T	probably damaging	Het
Pik3c2g	A	G	6: 139,935,985 (GRCm38)	E781G	probably benign	Het
Pik3r4	G	A	9: 105,678,176 (GRCm38)	V1111I	possibly damaging	Het
Pkd1l2	T	A	8: 116,995,842 (GRCm38)		probably null	Het
Plekhg1	T	A	10: 3,957,506 (GRCm38)	S808T	probably benign	Het
Pnkp	T	A	7: 44,860,454 (GRCm38)		probably benign	Het
Polr3c	A	T	3: 96,723,661 (GRCm38)	F148I	probably damaging	Het
Ppard	A	T	17: 28,286,443 (GRCm38)	T35S	probably benign	Het
Ptov1	T	C	7: 44,867,109 (GRCm38)	D134G	probably benign	Het
Ptprz1	T	A	6: 23,002,610 (GRCm38)	S1566R	probably benign	Het
Pum1	T	C	4: 130,718,193 (GRCm38)	S158P	probably benign	Het
Qki	T	C	17: 10,216,288 (GRCm38)	H269R	probably damaging	Het
Qrsl1	T	C	10: 43,876,663 (GRCm38)	Y388C	probably damaging	Het
Rapgef1	T	G	2: 29,689,160 (GRCm38)	I182S	probably damaging	Het
Ret	T	C	6: 118,163,193 (GRCm38)	S1013G	possibly damaging	Het
Rimbp3	A	G	16: 17,210,601 (GRCm38)	R630G	possibly damaging	Het
Rnmt	A	T	18: 68,317,960 (GRCm38)		probably benign	Het
Ryr2	A	T	13: 11,577,909 (GRCm38)	M4653K	possibly damaging	Het
Sacm1l	G	A	9: 123,590,830 (GRCm38)	V553I	probably benign	Het
Sec31b	A	T	19: 44,532,677 (GRCm38)	S110T	probably damaging	Het
Semg1	T	A	2: 164,237,123 (GRCm38)	D288V	possibly damaging	Het
Serpina3k	G	A	12: 104,340,860 (GRCm38)	G117D	probably damaging	Het
Sesn2	T	C	4: 132,494,591 (GRCm38)	Y410C	probably damaging	Het
Slc24a1	G	A	9: 64,949,554 (GRCm38)	R24C	probably benign	Het
Slc35g2	A	C	9: 100,552,502 (GRCm38)	V372G	probably benign	Het
Slc7a7	T	C	14: 54,408,733 (GRCm38)	Y91C	probably damaging	Het
Slc7a9	T	A	7: 35,453,563 (GRCm38)	Y135*	probably null	Het
Slco1a7	A	T	6: 141,723,179 (GRCm38)	M509K	probably benign	Het
Slco4a1	A	G	2: 180,473,615 (GRCm38)	N662D	probably damaging	Het
Slfn4	T	A	11: 83,189,282 (GRCm38)		probably benign	Het
Slmap	T	C	14: 26,468,535 (GRCm38)	N156S	probably damaging	Het
Smim29	A	G	17: 27,565,270 (GRCm38)		probably benign	Het
Snx18	A	G	13: 113,617,774 (GRCm38)	S208P	probably benign	Het
Sorbs1	T	A	19: 40,314,689 (GRCm38)	R485S	probably benign	Het
Spib	A	G	7: 44,528,885 (GRCm38)	S154P	probably damaging	Het
Spty2d1	T	C	7: 46,996,110 (GRCm38)	D595G	probably damaging	Het
St7	T	A	6: 17,906,516 (GRCm38)		probably null	Het
Susd1	T	C	4: 59,428,029 (GRCm38)	T52A	possibly damaging	Het
Syt7	T	A	19: 10,442,924 (GRCm38)	I355N	probably damaging	Het
Tarm1	G	A	7: 3,496,900 (GRCm38)	Q145*	probably null	Het
Teddm2	T	A	1: 153,850,741 (GRCm38)	E76V	probably damaging	Het
Thsd7b	T	C	1: 129,613,186 (GRCm38)	S343P	probably damaging	Het
Tigd2	T	A	6: 59,211,415 (GRCm38)	H422Q	probably benign	Het
Tle1	T	C	4: 72,125,019 (GRCm38)	N538D	possibly damaging	Het
Tmc2	A	G	2: 130,261,397 (GRCm38)		probably null	Het
Tmtc1	A	C	6: 148,284,980 (GRCm38)		probably null	Het
Tns3	C	T	11: 8,450,986 (GRCm38)	R1104H	probably benign	Het
Trim6	T	C	7: 104,232,648 (GRCm38)	Y369H	probably damaging	Het
Triobp	G	A	15: 78,967,113 (GRCm38)	R489K	probably damaging	Het
Trpv4	T	C	5: 114,622,753 (GRCm38)	D732G	possibly damaging	Het
Trrap	G	A	5: 144,816,570 (GRCm38)	V1883I	probably damaging	Het
Tsc2	C	A	17: 24,603,275 (GRCm38)	V1141F	possibly damaging	Het
Ttn	A	T	2: 76,943,011 (GRCm38)	M2395K	unknown	Het
Ttn	A	G	2: 76,899,827 (GRCm38)		probably benign	Het
Tyrp1	A	T	4: 80,844,935 (GRCm38)	D353V	possibly damaging	Het
Ubd	A	C	17: 37,195,702 (GRCm38)	T160P	probably benign	Het
Ugt2b36	G	T	5: 87,081,538 (GRCm38)	Y156*	probably null	Het
Ulk4	G	A	9: 121,263,638 (GRCm38)	R178*	probably null	Het
Unc13d	A	G	11: 116,073,582 (GRCm38)	V312A	possibly damaging	Het
Urb2	G	T	8: 124,028,897 (GRCm38)	A448S	probably damaging	Het
Urod	G	A	4: 116,991,673 (GRCm38)	A92V	possibly damaging	Het
Vmn1r33	T	A	6: 66,611,819 (GRCm38)	R250S	probably benign	Het
Vmn1r87	A	T	7: 13,132,327 (GRCm38)	M11K	possibly damaging	Het
Vmn2r77	C	T	7: 86,800,987 (GRCm38)	T147I	probably benign	Het
Vstm4	A	G	14: 32,917,902 (GRCm38)	K96E	possibly damaging	Het
Vxn	T	C	1: 9,606,976 (GRCm38)	S24P	probably benign	Het
Washc4	A	T	10: 83,574,479 (GRCm38)	M644L	probably benign	Het
Wwp1	T	C	4: 19,661,990 (GRCm38)	D172G	probably benign	Het
Zbtb38	A	T	9: 96,687,684 (GRCm38)	V449E	probably damaging	Het
Zfhx4	T	C	3: 5,214,807 (GRCm38)		probably benign	Het
Zfp229	C	T	17: 21,745,286 (GRCm38)	H166Y	possibly damaging	Het
Zfp512b	A	G	2: 181,588,739 (GRCm38)	S453P	probably benign	Het
Zp2	C	A	7: 120,138,120 (GRCm38)	V282L	probably damaging	Het

Other mutations in Dnhd1

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00321:Dnhd1	APN	7	105,677,995 (GRCm38)	missense	probably damaging	1.00
IGL00516:Dnhd1	APN	7	105,657,211 (GRCm38)	missense	possibly damaging	0.52
IGL00576:Dnhd1	APN	7	105,692,675 (GRCm38)	missense	probably damaging	1.00
IGL00990:Dnhd1	APN	7	105,721,688 (GRCm38)	missense	possibly damaging	0.85
IGL01346:Dnhd1	APN	7	105,713,909 (GRCm38)	missense	probably benign
IGL01714:Dnhd1	APN	7	105,720,942 (GRCm38)	missense	probably damaging	1.00
IGL01735:Dnhd1	APN	7	105,713,754 (GRCm38)	missense	probably benign	0.37
IGL01814:Dnhd1	APN	7	105,652,030 (GRCm38)	missense	probably benign
IGL01999:Dnhd1	APN	7	105,721,215 (GRCm38)	missense	possibly damaging	0.50
IGL02022:Dnhd1	APN	7	105,678,309 (GRCm38)	missense	probably damaging	1.00
IGL02131:Dnhd1	APN	7	105,720,802 (GRCm38)	missense	probably damaging	1.00
IGL02156:Dnhd1	APN	7	105,721,744 (GRCm38)	missense	probably damaging	1.00
IGL02674:Dnhd1	APN	7	105,721,481 (GRCm38)	missense	probably benign	0.00
IGL02966:Dnhd1	APN	7	105,720,741 (GRCm38)	missense	probably benign	0.00
IGL03066:Dnhd1	APN	7	105,719,882 (GRCm38)	missense	probably damaging	0.99
IGL03298:Dnhd1	APN	7	105,714,475 (GRCm38)	missense	probably damaging	0.98
IGL03378:Dnhd1	APN	7	105,713,733 (GRCm38)	missense	possibly damaging	0.87
IGL02802:Dnhd1	UTSW	7	105,655,723 (GRCm38)	missense	possibly damaging	0.83
R0060:Dnhd1	UTSW	7	105,668,514 (GRCm38)	missense	probably damaging	0.99
R0129:Dnhd1	UTSW	7	105,720,924 (GRCm38)	missense	probably benign	0.19
R0238:Dnhd1	UTSW	7	105,721,531 (GRCm38)	missense	probably benign	0.06
R0238:Dnhd1	UTSW	7	105,721,531 (GRCm38)	missense	probably benign	0.06
R0239:Dnhd1	UTSW	7	105,721,531 (GRCm38)	missense	probably benign	0.06
R0239:Dnhd1	UTSW	7	105,721,531 (GRCm38)	missense	probably benign	0.06
R0384:Dnhd1	UTSW	7	105,720,114 (GRCm38)	missense	possibly damaging	0.56
R0453:Dnhd1	UTSW	7	105,674,444 (GRCm38)	missense	probably benign	0.00
R0540:Dnhd1	UTSW	7	105,720,788 (GRCm38)	missense	probably benign	0.04
R0554:Dnhd1	UTSW	7	105,694,395 (GRCm38)	missense	probably benign	0.10
R0576:Dnhd1	UTSW	7	105,714,045 (GRCm38)	missense	probably damaging	1.00
R0607:Dnhd1	UTSW	7	105,720,788 (GRCm38)	missense	probably benign	0.04
R0631:Dnhd1	UTSW	7	105,651,624 (GRCm38)	missense	probably benign	0.17
R0639:Dnhd1	UTSW	7	105,696,464 (GRCm38)	missense	possibly damaging	0.95
R0668:Dnhd1	UTSW	7	105,695,751 (GRCm38)	missense	probably benign
R0669:Dnhd1	UTSW	7	105,693,704 (GRCm38)	missense	probably benign	0.01
R0670:Dnhd1	UTSW	7	105,696,464 (GRCm38)	missense	possibly damaging	0.95
R0699:Dnhd1	UTSW	7	105,651,906 (GRCm38)	missense	probably damaging	0.98
R1019:Dnhd1	UTSW	7	105,709,171 (GRCm38)	missense	probably damaging	1.00
R1144:Dnhd1	UTSW	7	105,713,031 (GRCm38)	missense	probably damaging	1.00
R1226:Dnhd1	UTSW	7	105,696,899 (GRCm38)	missense	probably damaging	1.00
R1257:Dnhd1	UTSW	7	105,694,153 (GRCm38)	missense	probably damaging	1.00
R1391:Dnhd1	UTSW	7	105,720,124 (GRCm38)	missense	probably damaging	1.00
R1453:Dnhd1	UTSW	7	105,721,273 (GRCm38)	critical splice donor site	probably null
R1501:Dnhd1	UTSW	7	105,668,463 (GRCm38)	missense	probably benign	0.00
R1503:Dnhd1	UTSW	7	105,693,660 (GRCm38)	missense	possibly damaging	0.67
R1515:Dnhd1	UTSW	7	105,704,148 (GRCm38)	missense	probably benign	0.11
R1615:Dnhd1	UTSW	7	105,713,706 (GRCm38)	missense	possibly damaging	0.74
R1615:Dnhd1	UTSW	7	105,703,206 (GRCm38)	missense	probably benign	0.00
R1656:Dnhd1	UTSW	7	105,714,281 (GRCm38)	missense	probably damaging	1.00
R1720:Dnhd1	UTSW	7	105,693,828 (GRCm38)	missense	probably benign
R1723:Dnhd1	UTSW	7	105,714,920 (GRCm38)	missense	possibly damaging	0.60
R1766:Dnhd1	UTSW	7	105,693,972 (GRCm38)	missense	possibly damaging	0.50
R1799:Dnhd1	UTSW	7	105,655,767 (GRCm38)	missense	probably benign	0.31
R1860:Dnhd1	UTSW	7	105,704,205 (GRCm38)	missense	probably benign
R1920:Dnhd1	UTSW	7	105,713,407 (GRCm38)	missense	probably benign	0.00
R1925:Dnhd1	UTSW	7	105,673,854 (GRCm38)	missense	probably damaging	0.96
R1925:Dnhd1	UTSW	7	105,652,252 (GRCm38)	missense	probably damaging	1.00
R1934:Dnhd1	UTSW	7	105,708,582 (GRCm38)	missense	probably benign	0.05
R1935:Dnhd1	UTSW	7	105,673,976 (GRCm38)	missense	probably benign	0.09
R1936:Dnhd1	UTSW	7	105,673,976 (GRCm38)	missense	probably benign	0.09
R2035:Dnhd1	UTSW	7	105,704,921 (GRCm38)	missense	probably damaging	0.99
R2125:Dnhd1	UTSW	7	105,677,971 (GRCm38)	missense	probably benign	0.35
R2127:Dnhd1	UTSW	7	105,693,721 (GRCm38)	missense	possibly damaging	0.56
R2254:Dnhd1	UTSW	7	105,703,772 (GRCm38)	missense	probably damaging	1.00
R2301:Dnhd1	UTSW	7	105,705,399 (GRCm38)	missense	probably damaging	1.00
R2316:Dnhd1	UTSW	7	105,674,421 (GRCm38)	missense	probably damaging	1.00
R2324:Dnhd1	UTSW	7	105,710,090 (GRCm38)	missense	probably damaging	1.00
R2337:Dnhd1	UTSW	7	105,703,467 (GRCm38)	missense	probably benign	0.07
R2381:Dnhd1	UTSW	7	105,693,664 (GRCm38)	missense	probably benign	0.42
R2394:Dnhd1	UTSW	7	105,720,231 (GRCm38)	missense	probably benign	0.19
R2862:Dnhd1	UTSW	7	105,712,559 (GRCm38)	missense	probably benign	0.01
R3038:Dnhd1	UTSW	7	105,720,229 (GRCm38)	missense	probably damaging	0.99
R3114:Dnhd1	UTSW	7	105,696,565 (GRCm38)	critical splice donor site	probably null
R3404:Dnhd1	UTSW	7	105,694,761 (GRCm38)	nonsense	probably null
R3405:Dnhd1	UTSW	7	105,694,761 (GRCm38)	nonsense	probably null
R3439:Dnhd1	UTSW	7	105,694,785 (GRCm38)	missense	probably damaging	1.00
R3959:Dnhd1	UTSW	7	105,713,122 (GRCm38)	missense	probably benign	0.21
R4014:Dnhd1	UTSW	7	105,714,838 (GRCm38)	missense	probably damaging	0.99
R4084:Dnhd1	UTSW	7	105,709,588 (GRCm38)	missense	probably damaging	1.00
R4181:Dnhd1	UTSW	7	105,693,954 (GRCm38)	missense	probably damaging	1.00
R4255:Dnhd1	UTSW	7	105,712,998 (GRCm38)	missense	probably damaging	1.00
R4302:Dnhd1	UTSW	7	105,693,954 (GRCm38)	missense	probably damaging	1.00
R4440:Dnhd1	UTSW	7	105,696,728 (GRCm38)	nonsense	probably null
R4565:Dnhd1	UTSW	7	105,651,956 (GRCm38)	missense	possibly damaging	0.92
R4569:Dnhd1	UTSW	7	105,657,166 (GRCm38)	splice site	probably null
R4584:Dnhd1	UTSW	7	105,678,049 (GRCm38)	missense	probably damaging	1.00
R4586:Dnhd1	UTSW	7	105,678,049 (GRCm38)	missense	probably damaging	1.00
R4590:Dnhd1	UTSW	7	105,714,030 (GRCm38)	missense	probably damaging	1.00
R4593:Dnhd1	UTSW	7	105,715,446 (GRCm38)	missense	probably benign	0.02
R4600:Dnhd1	UTSW	7	105,703,644 (GRCm38)	missense	probably damaging	1.00
R4705:Dnhd1	UTSW	7	105,655,741 (GRCm38)	missense	probably damaging	1.00
R4731:Dnhd1	UTSW	7	105,673,849 (GRCm38)	missense	probably benign	0.00
R4733:Dnhd1	UTSW	7	105,673,849 (GRCm38)	missense	probably benign	0.00
R4786:Dnhd1	UTSW	7	105,674,444 (GRCm38)	missense	probably benign	0.00
R4791:Dnhd1	UTSW	7	105,721,117 (GRCm38)	missense	probably damaging	1.00
R4811:Dnhd1	UTSW	7	105,714,281 (GRCm38)	missense	probably damaging	0.99
R4822:Dnhd1	UTSW	7	105,703,964 (GRCm38)	missense	probably benign	0.00
R4886:Dnhd1	UTSW	7	105,714,808 (GRCm38)	missense	probably benign	0.00
R4890:Dnhd1	UTSW	7	105,656,957 (GRCm38)	missense	possibly damaging	0.47
R4973:Dnhd1	UTSW	7	105,713,633 (GRCm38)	missense	probably benign	0.24
R5007:Dnhd1	UTSW	7	105,713,076 (GRCm38)	missense	probably damaging	1.00
R5048:Dnhd1	UTSW	7	105,693,697 (GRCm38)	missense	probably benign	0.01
R5151:Dnhd1	UTSW	7	105,713,440 (GRCm38)	missense	probably benign	0.22
R5179:Dnhd1	UTSW	7	105,714,552 (GRCm38)	missense	probably damaging	1.00
R5182:Dnhd1	UTSW	7	105,703,209 (GRCm38)	missense	probably damaging	1.00
R5183:Dnhd1	UTSW	7	105,703,209 (GRCm38)	missense	probably damaging	1.00
R5185:Dnhd1	UTSW	7	105,703,209 (GRCm38)	missense	probably damaging	1.00
R5209:Dnhd1	UTSW	7	105,696,460 (GRCm38)	missense	probably benign	0.00
R5225:Dnhd1	UTSW	7	105,703,923 (GRCm38)	missense	possibly damaging	0.73
R5250:Dnhd1	UTSW	7	105,685,761 (GRCm38)	missense	probably damaging	1.00
R5257:Dnhd1	UTSW	7	105,674,037 (GRCm38)	missense	probably benign
R5258:Dnhd1	UTSW	7	105,674,037 (GRCm38)	missense	probably benign
R5273:Dnhd1	UTSW	7	105,714,482 (GRCm38)	missense	probably damaging	0.99
R5288:Dnhd1	UTSW	7	105,714,437 (GRCm38)	missense	possibly damaging	0.94
R5396:Dnhd1	UTSW	7	105,713,684 (GRCm38)	missense	probably benign	0.00
R5453:Dnhd1	UTSW	7	105,710,123 (GRCm38)	missense	probably damaging	1.00
R5511:Dnhd1	UTSW	7	105,714,156 (GRCm38)	missense	probably damaging	1.00
R5518:Dnhd1	UTSW	7	105,703,209 (GRCm38)	missense	probably damaging	1.00
R5523:Dnhd1	UTSW	7	105,703,209 (GRCm38)	missense	probably damaging	1.00
R5528:Dnhd1	UTSW	7	105,703,209 (GRCm38)	missense	probably damaging	1.00
R5529:Dnhd1	UTSW	7	105,703,209 (GRCm38)	missense	probably damaging	1.00
R5561:Dnhd1	UTSW	7	105,714,821 (GRCm38)	missense	probably damaging	0.99
R5681:Dnhd1	UTSW	7	105,703,209 (GRCm38)	missense	probably damaging	1.00
R5682:Dnhd1	UTSW	7	105,703,209 (GRCm38)	missense	probably damaging	1.00
R5683:Dnhd1	UTSW	7	105,703,209 (GRCm38)	missense	probably damaging	1.00
R5684:Dnhd1	UTSW	7	105,703,209 (GRCm38)	missense	probably damaging	1.00
R5686:Dnhd1	UTSW	7	105,703,209 (GRCm38)	missense	probably damaging	1.00
R5697:Dnhd1	UTSW	7	105,674,188 (GRCm38)	missense	probably damaging	1.00
R5789:Dnhd1	UTSW	7	105,705,010 (GRCm38)	missense	possibly damaging	0.50
R5790:Dnhd1	UTSW	7	105,655,774 (GRCm38)	missense	probably damaging	1.00
R5814:Dnhd1	UTSW	7	105,719,895 (GRCm38)	missense	possibly damaging	0.69
R5828:Dnhd1	UTSW	7	105,720,181 (GRCm38)	missense	probably benign	0.00
R5852:Dnhd1	UTSW	7	105,695,748 (GRCm38)	missense	probably damaging	1.00
R5883:Dnhd1	UTSW	7	105,720,504 (GRCm38)	missense	probably damaging	0.98
R6115:Dnhd1	UTSW	7	105,713,987 (GRCm38)	missense	probably benign	0.00
R6119:Dnhd1	UTSW	7	105,709,440 (GRCm38)	missense	probably benign	0.18
R6212:Dnhd1	UTSW	7	105,704,048 (GRCm38)	missense	probably damaging	1.00
R6243:Dnhd1	UTSW	7	105,652,009 (GRCm38)	missense	probably damaging	1.00
R6265:Dnhd1	UTSW	7	105,693,370 (GRCm38)	missense	probably benign	0.07
R6332:Dnhd1	UTSW	7	105,694,066 (GRCm38)	missense	probably benign	0.02
R6344:Dnhd1	UTSW	7	105,694,610 (GRCm38)	missense	probably benign	0.38
R6477:Dnhd1	UTSW	7	105,677,886 (GRCm38)	missense	probably benign	0.05
R6642:Dnhd1	UTSW	7	105,703,799 (GRCm38)	missense	probably benign
R6663:Dnhd1	UTSW	7	105,685,692 (GRCm38)	splice site	probably null
R6730:Dnhd1	UTSW	7	105,703,875 (GRCm38)	missense	probably benign	0.00
R6748:Dnhd1	UTSW	7	105,720,637 (GRCm38)	missense	probably benign	0.03
R6833:Dnhd1	UTSW	7	105,703,373 (GRCm38)	missense	probably benign	0.01
R6850:Dnhd1	UTSW	7	105,719,930 (GRCm38)	missense	possibly damaging	0.68
R6853:Dnhd1	UTSW	7	105,703,728 (GRCm38)	missense	probably benign
R6860:Dnhd1	UTSW	7	105,678,266 (GRCm38)	missense	probably benign
R6898:Dnhd1	UTSW	7	105,687,377 (GRCm38)	missense	probably damaging	0.99
R6927:Dnhd1	UTSW	7	105,715,563 (GRCm38)	missense	probably damaging	1.00
R6952:Dnhd1	UTSW	7	105,713,688 (GRCm38)	missense	probably damaging	1.00
R6987:Dnhd1	UTSW	7	105,704,585 (GRCm38)	missense	probably damaging	0.98
R6988:Dnhd1	UTSW	7	105,714,210 (GRCm38)	missense	probably damaging	1.00
R7022:Dnhd1	UTSW	7	105,720,798 (GRCm38)	missense	probably benign	0.36
R7053:Dnhd1	UTSW	7	105,694,954 (GRCm38)	missense	probably damaging	1.00
R7085:Dnhd1	UTSW	7	105,715,261 (GRCm38)	missense	probably benign	0.26
R7086:Dnhd1	UTSW	7	105,708,532 (GRCm38)	missense	probably benign	0.03
R7112:Dnhd1	UTSW	7	105,713,985 (GRCm38)	missense	probably damaging	1.00
R7140:Dnhd1	UTSW	7	105,693,766 (GRCm38)	missense	probably benign	0.00
R7151:Dnhd1	UTSW	7	105,710,027 (GRCm38)	missense	probably benign	0.03
R7178:Dnhd1	UTSW	7	105,694,993 (GRCm38)	missense	probably damaging	0.98
R7326:Dnhd1	UTSW	7	105,720,930 (GRCm38)	missense	probably damaging	0.96
R7345:Dnhd1	UTSW	7	105,703,967 (GRCm38)	missense	probably benign	0.17
R7349:Dnhd1	UTSW	7	105,710,123 (GRCm38)	missense	probably damaging	1.00
R7397:Dnhd1	UTSW	7	105,705,297 (GRCm38)	missense	possibly damaging	0.87
R7520:Dnhd1	UTSW	7	105,696,048 (GRCm38)	missense	probably benign	0.07
R7536:Dnhd1	UTSW	7	105,709,561 (GRCm38)	missense	probably damaging	1.00
R7539:Dnhd1	UTSW	7	105,720,912 (GRCm38)	missense	probably damaging	1.00
R7541:Dnhd1	UTSW	7	105,678,309 (GRCm38)	missense	probably damaging	1.00
R7619:Dnhd1	UTSW	7	105,674,268 (GRCm38)	missense	probably benign	0.01
R7676:Dnhd1	UTSW	7	105,684,087 (GRCm38)	missense	probably benign	0.09
R7689:Dnhd1	UTSW	7	105,713,963 (GRCm38)	missense	probably benign	0.07
R7712:Dnhd1	UTSW	7	105,651,624 (GRCm38)	missense	probably benign	0.17
R7729:Dnhd1	UTSW	7	105,705,265 (GRCm38)	missense	probably damaging	1.00
R7767:Dnhd1	UTSW	7	105,694,610 (GRCm38)	missense	probably benign	0.38
R7768:Dnhd1	UTSW	7	105,721,095 (GRCm38)	missense	possibly damaging	0.87
R7779:Dnhd1	UTSW	7	105,677,915 (GRCm38)	missense	probably benign	0.01
R7879:Dnhd1	UTSW	7	105,703,439 (GRCm38)	missense	probably benign	0.09
R7922:Dnhd1	UTSW	7	105,668,514 (GRCm38)	missense	probably damaging	1.00
R7951:Dnhd1	UTSW	7	105,678,004 (GRCm38)	missense	probably damaging	1.00
R8259:Dnhd1	UTSW	7	105,694,788 (GRCm38)	missense	probably benign	0.38
R8350:Dnhd1	UTSW	7	105,678,024 (GRCm38)	missense	probably damaging	0.99
R8380:Dnhd1	UTSW	7	105,677,866 (GRCm38)	missense	probably benign	0.31
R8392:Dnhd1	UTSW	7	105,703,343 (GRCm38)	missense	possibly damaging	0.84
R8478:Dnhd1	UTSW	7	105,682,794 (GRCm38)	missense	probably benign	0.00
R8708:Dnhd1	UTSW	7	105,694,280 (GRCm38)	nonsense	probably null
R8767:Dnhd1	UTSW	7	105,652,123 (GRCm38)	missense	probably damaging	1.00
R8825:Dnhd1	UTSW	7	105,693,967 (GRCm38)	missense	possibly damaging	0.95
R8849:Dnhd1	UTSW	7	105,721,516 (GRCm38)	missense	probably benign	0.00
R8903:Dnhd1	UTSW	7	105,713,648 (GRCm38)	nonsense	probably null
R8910:Dnhd1	UTSW	7	105,683,697 (GRCm38)	missense	possibly damaging	0.92
R8940:Dnhd1	UTSW	7	105,714,647 (GRCm38)	intron	probably benign
R8954:Dnhd1	UTSW	7	105,694,779 (GRCm38)	missense	probably benign	0.35
R8956:Dnhd1	UTSW	7	105,692,645 (GRCm38)	missense	probably damaging	0.99
R8971:Dnhd1	UTSW	7	105,709,321 (GRCm38)	nonsense	probably null
R8996:Dnhd1	UTSW	7	105,674,035 (GRCm38)	missense	probably damaging	1.00
R9051:Dnhd1	UTSW	7	105,692,726 (GRCm38)	missense	possibly damaging	0.54
R9058:Dnhd1	UTSW	7	105,684,063 (GRCm38)	missense	probably benign	0.01
R9109:Dnhd1	UTSW	7	105,683,966 (GRCm38)	missense	probably damaging	0.98
R9284:Dnhd1	UTSW	7	105,651,884 (GRCm38)	missense	probably damaging	1.00
R9295:Dnhd1	UTSW	7	105,714,141 (GRCm38)	missense	probably benign
R9298:Dnhd1	UTSW	7	105,683,966 (GRCm38)	missense	probably damaging	0.98
R9299:Dnhd1	UTSW	7	105,720,599 (GRCm38)	missense	probably benign	0.00
R9308:Dnhd1	UTSW	7	105,704,277 (GRCm38)	missense	probably damaging	1.00
R9337:Dnhd1	UTSW	7	105,720,599 (GRCm38)	missense	probably benign	0.00
R9385:Dnhd1	UTSW	7	105,712,765 (GRCm38)	missense	probably damaging	1.00
R9463:Dnhd1	UTSW	7	105,695,016 (GRCm38)	missense	probably benign
R9463:Dnhd1	UTSW	7	105,657,247 (GRCm38)	missense	probably benign	0.00
R9476:Dnhd1	UTSW	7	105,703,682 (GRCm38)	missense	possibly damaging	0.74
R9489:Dnhd1	UTSW	7	105,651,597 (GRCm38)	missense	probably benign
R9500:Dnhd1	UTSW	7	105,704,502 (GRCm38)	missense	probably benign
R9510:Dnhd1	UTSW	7	105,703,682 (GRCm38)	missense	possibly damaging	0.74
R9513:Dnhd1	UTSW	7	105,704,972 (GRCm38)	missense	probably damaging	1.00
R9537:Dnhd1	UTSW	7	105,695,533 (GRCm38)	missense	probably damaging	0.99
R9567:Dnhd1	UTSW	7	105,704,266 (GRCm38)	missense	probably benign	0.03
R9622:Dnhd1	UTSW	7	105,704,135 (GRCm38)	missense	probably benign
R9623:Dnhd1	UTSW	7	105,694,927 (GRCm38)	missense	probably damaging	1.00
R9623:Dnhd1	UTSW	7	105,686,566 (GRCm38)	missense	probably damaging	1.00
R9674:Dnhd1	UTSW	7	105,714,222 (GRCm38)	missense	probably damaging	1.00
R9756:Dnhd1	UTSW	7	105,703,928 (GRCm38)	missense	probably benign	0.19
R9777:Dnhd1	UTSW	7	105,720,249 (GRCm38)	missense	probably benign	0.14
R9778:Dnhd1	UTSW	7	105,704,033 (GRCm38)	missense	probably benign
R9781:Dnhd1	UTSW	7	105,703,710 (GRCm38)	missense	probably benign	0.31
R9796:Dnhd1	UTSW	7	105,693,330 (GRCm38)	missense	probably damaging	1.00
Z1088:Dnhd1	UTSW	7	105,712,727 (GRCm38)	missense	probably benign	0.00
Z1176:Dnhd1	UTSW	7	105,703,036 (GRCm38)	critical splice acceptor site	probably null
Z1176:Dnhd1	UTSW	7	105,678,299 (GRCm38)	missense	probably benign
Z1176:Dnhd1	UTSW	7	105,668,547 (GRCm38)	missense	probably damaging	0.98
Z1176:Dnhd1	UTSW	7	105,703,580 (GRCm38)	frame shift	probably null
Z1177:Dnhd1	UTSW	7	105,682,841 (GRCm38)	missense	possibly damaging	0.90

Predicted Primers

Posted On

2017-03-08