Mutagenetix > Incidental Mutation

Incidental Mutation 'R4801:Otogl'

472885

Institutional Source

Beutler Lab

Gene Symbol

Otogl

Ensembl Gene

ENSMUSG00000091455

Gene Name

otogelin-like

Synonyms

Gm6924

MMRRC Submission

042423-MU

Accession Numbers

Essential gene?

Non essential (E-score: 0.000) question?

Stock #

R4801 (G1)

Quality Score

225

Status

Not validated

Chromosome

Chromosomal Location

107760531-107912134 bp(-) (GRCm38)

Type of Mutation

missense

DNA Base Change (assembly)

A to C at 107901336 bp (GRCm38)

Zygosity

Heterozygous

Amino Acid Change

Cysteine to Tryptophan at position 72 (C72W)

Ref Sequence

ENSEMBL: ENSMUSP00000129467 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000165341]

AlphaFold

F7A4A7

Predicted Effect

probably damaging
Transcript: ENSMUST00000165341
AA Change: C72W

PolyPhen 2 Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)

SMART Domains

Protein: ENSMUSP00000129467
Gene: ENSMUSG00000091455
AA Change: C72W

Domain	Start	End	E-Value	Type
signal peptide	1	22	N/A	INTRINSIC
EGF_like	71	101	3.36e1	SMART
VWD	104	264	4.74e-29	SMART
C8	305	378	6.13e-6	SMART
VWD	463	625	7e-41	SMART
C8	668	733	3.6e-3	SMART
Pfam:TIL	736	791	2.3e-11	PFAM
SCOP:d1coua_	833	911	1e-6	SMART
VWD	928	1085	1.29e-30	SMART
C8	1120	1194	1.81e-26	SMART
Pfam:AbfB	1230	1350	1.2e-10	PFAM
Pfam:TIL	1364	1418	6.1e-8	PFAM
VWD	1497	1671	2.34e-10	SMART
C8	1705	1775	9.56e-17	SMART
Pfam:TIL	1778	1836	1.6e-8	PFAM
low complexity region	1870	1886	N/A	INTRINSIC
CT	2242	2325	6.9e-14	SMART

Meta Mutation Damage Score

0.1565

Coding Region Coverage

1x: 99.2%
3x: 98.6%
10x: 97.1%
20x: 94.8%

Validation Efficiency

99% (88/89)

MGI Phenotype

FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] The protein encoded by this gene belongs to the otogelin family. This gene is expressed in the inner ear of vertebrates with the highest level of expression seen at the embryonic stage and lowest in adult. Knockdown studies in zebrafish suggest that this gene is essential for normal inner ear function. Mutations in this gene are associated with autosomal recessive deafness. [provided by RefSeq, Dec 2012]

Allele List at MGI

Other mutations in this stock

Total: 164 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
2310057J18Rik	A	G	10: 28,983,926 (GRCm38)		probably null	Het
Aadacl3	A	G	4: 144,456,232 (GRCm38)	I222T	probably damaging	Het
Abca13	G	T	11: 9,522,341 (GRCm38)	G4249V	possibly damaging	Het
Abcb10	A	G	8: 123,966,527 (GRCm38)	V346A	probably benign	Het
Abcc2	A	T	19: 43,819,361 (GRCm38)	I814F	probably damaging	Het
AF366264	T	A	8: 13,836,970 (GRCm38)	I374F	possibly damaging	Het
Alkbh2	C	T	5: 114,124,226 (GRCm38)	E148K	probably damaging	Het
Ankrd28	A	C	14: 31,736,830 (GRCm38)	D335E	probably damaging	Het
Ankrd44	T	C	1: 54,762,316 (GRCm38)	H284R	probably damaging	Het
Arfgef3	G	T	10: 18,591,906 (GRCm38)	Q1849K	probably benign	Het
Atp2c2	T	C	8: 119,747,687 (GRCm38)	M490T	probably damaging	Het
Bach1	T	A	16: 87,722,452 (GRCm38)	D543E	probably damaging	Het
Bahcc1	G	A	11: 120,282,225 (GRCm38)	V1558I	probably benign	Het
Bbs5	T	A	2: 69,655,614 (GRCm38)	W168R	probably damaging	Het
Bcar3	A	T	3: 122,529,594 (GRCm38)	D766V	probably benign	Het
C1ra	A	G	6: 124,513,768 (GRCm38)	D40G	probably benign	Het
Ccdc138	G	A	10: 58,573,643 (GRCm38)	C598Y	probably damaging	Het
Cd200r3	T	A	16: 44,957,825 (GRCm38)	N197K	possibly damaging	Het
Cenpf	T	A	1: 189,651,220 (GRCm38)	E2634D	probably damaging	Het
Cisd2	T	C	3: 135,411,141 (GRCm38)	K63R	probably damaging	Het
Clca3a2	A	T	3: 144,807,351 (GRCm38)	S478T	possibly damaging	Het
Clptm1l	T	C	13: 73,607,862 (GRCm38)	M199T	possibly damaging	Het
Cntnap4	T	A	8: 112,773,590 (GRCm38)	S505T	possibly damaging	Het
Cr2	C	T	1: 195,163,311 (GRCm38)	G112D	probably damaging	Het
Crb2	T	A	2: 37,793,756 (GRCm38)	I1090N	probably benign	Het
Csmd3	G	T	15: 47,621,292 (GRCm38)	P3057Q	probably damaging	Het
Ctso	G	A	3: 81,954,240 (GRCm38)	V307I	probably damaging	Het
Cyp3a41b	T	A	5: 145,573,651 (GRCm38)	T138S	probably benign	Het
Dctn3	G	T	4: 41,719,904 (GRCm38)	Y67*	probably null	Het
Dennd4c	C	A	4: 86,819,884 (GRCm38)	Y918*	probably null	Het
Dlg5	C	T	14: 24,154,689 (GRCm38)	G1262D	probably damaging	Het
Dnaaf1	G	A	8: 119,577,361 (GRCm38)	G46D	probably benign	Het
Dnah6	A	G	6: 73,089,698 (GRCm38)	V2563A	probably damaging	Het
Dnajc13	A	G	9: 104,175,727 (GRCm38)	Y1679H	probably benign	Het
Eif2ak3	T	C	6: 70,887,893 (GRCm38)	Y578H	probably benign	Het
Endod1	C	T	9: 14,357,023 (GRCm38)	V389M	probably benign	Het
Ephb4	T	C	5: 137,365,506 (GRCm38)	L582P	probably damaging	Het
Eps15	T	C	4: 109,324,217 (GRCm38)	L316S	possibly damaging	Het
Erbb4	G	T	1: 68,330,246 (GRCm38)	T412K	probably damaging	Het
Fam117a	T	A	11: 95,364,070 (GRCm38)	F90I	probably damaging	Het
Fam187b	T	G	7: 30,977,090 (GRCm38)	V8G	possibly damaging	Het
Fam84b	C	A	15: 60,823,944 (GRCm38)		probably benign	Het
Far1	T	A	7: 113,539,453 (GRCm38)	I59N	possibly damaging	Het
Fbxo34	T	A	14: 47,530,869 (GRCm38)	L562Q	probably damaging	Het
Frem1	T	A	4: 82,916,628 (GRCm38)		probably benign	Het
Gfra3	G	T	18: 34,720,192 (GRCm38)	P10Q	probably damaging	Het
Gm10698	A	G	9: 33,728,772 (GRCm38)		noncoding transcript	Het
Gm11487	C	T	4: 73,401,267 (GRCm38)	W80*	probably null	Het
Gm19965	T	A	1: 116,821,896 (GRCm38)	Y436N	probably benign	Het
Gm21818	T	A	13: 120,173,222 (GRCm38)	S13R	probably benign	Het
Gm5767	A	G	16: 8,683,345 (GRCm38)	T22A	unknown	Het
Gm5799	A	T	14: 43,544,548 (GRCm38)	H59L	probably damaging	Het
Gmppb	T	A	9: 108,050,217 (GRCm38)	V121E	probably benign	Het
Ighv7-4	G	C	12: 114,223,279 (GRCm38)		probably benign	Het
Ipo4	A	G	14: 55,631,214 (GRCm38)	S446P	probably damaging	Het
Itpr2	T	C	6: 146,371,331 (GRCm38)	T855A	probably damaging	Het
Jaml	T	C	9: 45,101,064 (GRCm38)	I283T	possibly damaging	Het
Kcnn2	T	C	18: 45,685,267 (GRCm38)		probably benign	Het
Klhl32	T	C	4: 24,649,698 (GRCm38)	Y399C	possibly damaging	Het
Lrriq1	G	A	10: 103,221,318 (GRCm38)	T207I	probably benign	Het
Lrriq3	A	T	3: 155,187,970 (GRCm38)	H436L	probably benign	Het
Mad2l1bp	T	C	17: 46,148,263 (GRCm38)	K114E	possibly damaging	Het
Mamstr	T	C	7: 45,642,418 (GRCm38)	V64A	possibly damaging	Het
Map4	T	A	9: 110,035,257 (GRCm38)	S517T	probably benign	Het
Matn1	A	T	4: 130,950,025 (GRCm38)	I182F	possibly damaging	Het
Mcm3	A	G	1: 20,810,156 (GRCm38)	I484T	probably damaging	Het
Med13	T	A	11: 86,278,773 (GRCm38)	I1922F	probably damaging	Het
Metap2	A	G	10: 93,868,895 (GRCm38)	V137A	probably damaging	Het
Mex3d	A	G	10: 80,386,954 (GRCm38)	V156A	possibly damaging	Het
Mfsd6	G	A	1: 52,709,596 (GRCm38)	P37S	probably benign	Het
Mkl1	T	C	15: 81,104,799 (GRCm38)	E7G	probably benign	Het
Mrgprx1	A	C	7: 48,021,211 (GRCm38)	S263A	possibly damaging	Het
Msl1	C	T	11: 98,803,969 (GRCm38)	R505*	probably null	Het
Mta2	T	C	19: 8,945,851 (GRCm38)	S96P	probably damaging	Het
Mtr	A	T	13: 12,195,251 (GRCm38)	N986K	probably benign	Het
Mut	A	G	17: 40,937,351 (GRCm38)	T90A	probably benign	Het
Mutyh	C	T	4: 116,817,029 (GRCm38)	T259I	probably benign	Het
Myof	T	C	19: 37,945,738 (GRCm38)	T908A	probably benign	Het
Nav2	A	T	7: 49,545,852 (GRCm38)	D992V	possibly damaging	Het
Neb	T	C	2: 52,200,703 (GRCm38)	T1352A	possibly damaging	Het
Nfix	CAAAAA	CAAAA	8: 84,716,247 (GRCm38)		probably null	Het
Nudt6	G	A	3: 37,405,354 (GRCm38)	R161C	probably benign	Het
Olfr1122	T	A	2: 87,388,209 (GRCm38)	V168E	probably benign	Het
Olfr1173	T	A	2: 88,274,879 (GRCm38)	M57L	probably damaging	Het
Olfr125	T	C	17: 37,835,349 (GRCm38)	Y117H	probably damaging	Het
Olfr1276	T	A	2: 111,257,152 (GRCm38)	F12L	probably damaging	Het
Olfr1411	T	A	1: 92,596,998 (GRCm38)	C160S	probably benign	Het
Olfr154	T	A	2: 85,664,278 (GRCm38)	D52V	probably damaging	Het
Olfr23	T	A	11: 73,940,870 (GRCm38)	I208K	possibly damaging	Het
Olfr319	T	C	11: 58,701,791 (GRCm38)	V30A	probably benign	Het
Olfr456	A	T	6: 42,486,679 (GRCm38)	N171K	probably benign	Het
Olfr744	A	G	14: 50,619,022 (GRCm38)	T267A	probably benign	Het
Olfr959	T	G	9: 39,572,858 (GRCm38)	M134L	probably benign	Het
Olr1	A	G	6: 129,488,090 (GRCm38)	F141S	possibly damaging	Het
Oprl1	G	T	2: 181,719,253 (GRCm38)	M340I	probably benign	Het
Pcdha11	T	A	18: 37,005,465 (GRCm38)	I49N	probably damaging	Het
Pcdha4	T	A	18: 36,953,955 (GRCm38)	L397*	probably null	Het
Pcdhb14	A	G	18: 37,448,278 (GRCm38)	S146G	probably benign	Het
Pclo	T	A	5: 14,675,815 (GRCm38)	H1562Q	unknown	Het
Pcsk9	T	C	4: 106,447,569 (GRCm38)	E434G	probably benign	Het
Phc2	A	G	4: 128,751,598 (GRCm38)	K833E	probably damaging	Het
Pja2	A	T	17: 64,292,862 (GRCm38)	S480R	probably damaging	Het
Pkd1	G	A	17: 24,578,096 (GRCm38)	G2493D	probably damaging	Het
Plk5	G	A	10: 80,359,304 (GRCm38)	V179M	possibly damaging	Het
Polr1a	G	A	6: 71,976,070 (GRCm38)	V1541I	probably benign	Het
Ppard	C	G	17: 28,286,374 (GRCm38)	R12G	unknown	Het
Ppp1r14a	A	G	7: 29,291,526 (GRCm38)	D73G	probably damaging	Het
Psd3	C	T	8: 68,121,148 (GRCm38)	R127H	probably benign	Het
Pten	G	T	19: 32,758,503 (GRCm38)	G20V	possibly damaging	Het
Ptprg	T	C	14: 11,554,233 (GRCm38)		probably benign	Het
Rad54l	T	C	4: 116,122,924 (GRCm38)	D21G	probably null	Het
Rgs14	T	C	13: 55,380,957 (GRCm38)	Y304H	probably damaging	Het
Rgs9	T	C	11: 109,240,868 (GRCm38)	K346R	probably damaging	Het
Rnf169	C	G	7: 99,926,446 (GRCm38)	G314A	probably damaging	Het
Rpgrip1l	T	A	8: 91,270,177 (GRCm38)	T692S	probably damaging	Het
Rtf1	T	C	2: 119,675,228 (GRCm38)	V54A	possibly damaging	Het
Rtn4	T	C	11: 29,708,660 (GRCm38)	V938A	probably benign	Het
Ryr2	T	C	13: 11,708,227 (GRCm38)	T2509A	probably damaging	Het
Ryr2	T	A	13: 11,687,932 (GRCm38)	D2890V	probably damaging	Het
Scel	A	C	14: 103,583,100 (GRCm38)	T348P	probably benign	Het
Scgb1b2	G	T	7: 31,291,573 (GRCm38)	L37I	possibly damaging	Het
Sdf4	A	G	4: 156,000,721 (GRCm38)	H171R	possibly damaging	Het
Sec31a	A	G	5: 100,393,363 (GRCm38)	V295A	probably damaging	Het
Setx	T	A	2: 29,146,373 (GRCm38)	S957T	probably benign	Het
Shroom3	G	T	5: 92,943,086 (GRCm38)	V1151F	probably damaging	Het
Six5	A	G	7: 19,096,969 (GRCm38)	N507S	probably benign	Het
Slc12a7	T	C	13: 73,763,892 (GRCm38)		probably null	Het
Slc1a7	T	A	4: 107,993,040 (GRCm38)	V116E	probably damaging	Het
Slc22a1	A	G	17: 12,675,535 (GRCm38)	L42P	probably damaging	Het
Slc25a31	A	T	3: 40,721,545 (GRCm38)	I174F	probably damaging	Het
Slc31a2	A	T	4: 62,292,632 (GRCm38)	M3L	probably damaging	Het
Slco1a4	T	A	6: 141,845,497 (GRCm38)		probably benign	Het
Smcr8	C	T	11: 60,778,610 (GRCm38)		probably null	Het
Smg5	G	T	3: 88,355,692 (GRCm38)	E801*	probably null	Het
Smgc	C	A	15: 91,854,616 (GRCm38)	H492Q	probably benign	Het
Smyd4	G	T	11: 75,403,184 (GRCm38)	G694V	probably damaging	Het
Sorcs3	A	G	19: 48,398,744 (GRCm38)	T223A	possibly damaging	Het
Stab1	G	T	14: 31,141,371 (GRCm38)	C2119*	probably null	Het
Taar9	A	G	10: 24,108,843 (GRCm38)	I231T	probably damaging	Het
Tacr2	A	G	10: 62,261,548 (GRCm38)	Y269C	probably damaging	Het
Taf3	T	G	2: 9,951,123 (GRCm38)	K744N	possibly damaging	Het
Tenm4	T	A	7: 96,906,245 (GRCm38)	V2682E	probably damaging	Het
Tet1	A	C	10: 62,822,663 (GRCm38)	L1468R	probably damaging	Het
Tgds	T	C	14: 118,117,033 (GRCm38)		probably benign	Het
Tgfb2	A	T	1: 186,628,913 (GRCm38)	Y380*	probably null	Het
Tgm5	T	G	2: 121,052,472 (GRCm38)	K435Q	probably damaging	Het
Themis	A	G	10: 28,761,511 (GRCm38)	T204A	probably benign	Het
Tm4sf1	T	C	3: 57,294,679 (GRCm38)	Y37C	probably damaging	Het
Tnn	T	C	1: 160,145,033 (GRCm38)	N333S	possibly damaging	Het
Tppp2	A	G	14: 51,919,348 (GRCm38)	N61D	probably benign	Het
Treml2	A	G	17: 48,309,159 (GRCm38)	T276A	probably benign	Het
Trit1	T	C	4: 123,016,638 (GRCm38)	V10A	probably benign	Het
Uba1y	T	G	Y: 825,890 (GRCm38)		probably null	Het
Uqcc1	T	C	2: 155,858,106 (GRCm38)		probably benign	Het
Vcam1	C	G	3: 116,115,935 (GRCm38)	G581A	probably damaging	Het
Vmn1r16	G	A	6: 57,323,190 (GRCm38)	T149I	probably benign	Het
Vmn1r209	T	C	13: 22,805,656 (GRCm38)	D288G	probably damaging	Het
Vmn1r78	T	A	7: 12,152,964 (GRCm38)	Y167*	probably null	Het
Vmn2r103	T	A	17: 19,795,076 (GRCm38)	S493T	probably benign	Het
Vmn2r105	T	A	17: 20,227,294 (GRCm38)	M423L	probably benign	Het
Vps13c	T	C	9: 67,964,282 (GRCm38)	F3244L	probably damaging	Het
Zfp119b	A	T	17: 55,939,642 (GRCm38)	D149E	probably damaging	Het
Zfp345	T	C	2: 150,473,308 (GRCm38)	Y103C	possibly damaging	Het
Zmym6	C	T	4: 127,123,216 (GRCm38)	T930I	probably benign	Het

Other mutations in Otogl

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
H8562:Otogl	UTSW	10	107,910,956 (GRCm38)	missense	probably benign	0.00
R0084:Otogl	UTSW	10	107,901,341 (GRCm38)	missense	probably damaging	0.96
R0164:Otogl	UTSW	10	107,874,530 (GRCm38)	missense	probably damaging	0.97
R0164:Otogl	UTSW	10	107,874,530 (GRCm38)	missense	probably damaging	0.97
R0238:Otogl	UTSW	10	107,806,696 (GRCm38)	missense	probably damaging	0.98
R0238:Otogl	UTSW	10	107,806,696 (GRCm38)	missense	probably damaging	0.98
R0239:Otogl	UTSW	10	107,806,696 (GRCm38)	missense	probably damaging	0.98
R0239:Otogl	UTSW	10	107,806,696 (GRCm38)	missense	probably damaging	0.98
R0294:Otogl	UTSW	10	107,777,228 (GRCm38)	missense	probably damaging	1.00
R0360:Otogl	UTSW	10	107,770,650 (GRCm38)	splice site	probably benign
R0442:Otogl	UTSW	10	107,876,855 (GRCm38)	missense	probably damaging	1.00
R0488:Otogl	UTSW	10	107,803,605 (GRCm38)	missense	probably benign	0.02
R0507:Otogl	UTSW	10	107,866,740 (GRCm38)	missense	possibly damaging	0.51
R0573:Otogl	UTSW	10	107,780,988 (GRCm38)	missense	probably benign	0.00
R0581:Otogl	UTSW	10	107,789,040 (GRCm38)	missense	possibly damaging	0.79
R0613:Otogl	UTSW	10	107,817,070 (GRCm38)	missense	probably damaging	0.99
R0614:Otogl	UTSW	10	107,798,355 (GRCm38)	missense	probably benign	0.14
R0742:Otogl	UTSW	10	107,866,740 (GRCm38)	missense	possibly damaging	0.51
R0846:Otogl	UTSW	10	107,772,296 (GRCm38)	missense	probably benign	0.40
R1146:Otogl	UTSW	10	107,886,513 (GRCm38)	missense	probably damaging	1.00
R1146:Otogl	UTSW	10	107,886,513 (GRCm38)	missense	probably damaging	1.00
R1439:Otogl	UTSW	10	107,779,252 (GRCm38)	missense	probably benign	0.02
R1457:Otogl	UTSW	10	107,878,152 (GRCm38)	splice site	probably null
R1526:Otogl	UTSW	10	107,869,526 (GRCm38)	missense	probably damaging	1.00
R1662:Otogl	UTSW	10	107,798,357 (GRCm38)	missense	possibly damaging	0.84
R1664:Otogl	UTSW	10	107,806,576 (GRCm38)	missense	probably benign	0.00
R1667:Otogl	UTSW	10	107,813,965 (GRCm38)	nonsense	probably null
R1695:Otogl	UTSW	10	107,814,017 (GRCm38)	missense	probably damaging	0.99
R1731:Otogl	UTSW	10	107,817,111 (GRCm38)	missense	probably damaging	1.00
R1733:Otogl	UTSW	10	107,783,712 (GRCm38)	missense	possibly damaging	0.46
R1764:Otogl	UTSW	10	107,899,461 (GRCm38)	nonsense	probably null
R1824:Otogl	UTSW	10	107,779,831 (GRCm38)	missense	probably benign
R1850:Otogl	UTSW	10	107,878,064 (GRCm38)	missense	probably damaging	1.00
R1856:Otogl	UTSW	10	107,854,264 (GRCm38)	missense	possibly damaging	0.92
R1875:Otogl	UTSW	10	107,899,590 (GRCm38)	missense	probably damaging	1.00
R1938:Otogl	UTSW	10	107,777,575 (GRCm38)	missense	probably damaging	0.98
R1986:Otogl	UTSW	10	107,794,190 (GRCm38)	critical splice acceptor site	probably null
R2072:Otogl	UTSW	10	107,781,043 (GRCm38)	missense	probably damaging	1.00
R2117:Otogl	UTSW	10	107,858,918 (GRCm38)	missense	probably benign	0.06
R2219:Otogl	UTSW	10	107,856,977 (GRCm38)	missense	probably damaging	1.00
R2508:Otogl	UTSW	10	107,874,500 (GRCm38)	missense	probably damaging	0.99
R2883:Otogl	UTSW	10	107,768,981 (GRCm38)	missense	probably damaging	1.00
R2931:Otogl	UTSW	10	107,820,004 (GRCm38)	missense	possibly damaging	0.85
R3620:Otogl	UTSW	10	107,874,371 (GRCm38)	missense	probably damaging	0.99
R3621:Otogl	UTSW	10	107,874,371 (GRCm38)	missense	probably damaging	0.99
R3735:Otogl	UTSW	10	107,899,529 (GRCm38)	nonsense	probably null
R3812:Otogl	UTSW	10	107,899,471 (GRCm38)	missense	probably damaging	1.00
R3880:Otogl	UTSW	10	107,827,704 (GRCm38)	missense	probably damaging	0.96
R3958:Otogl	UTSW	10	107,821,925 (GRCm38)	missense	probably damaging	1.00
R4063:Otogl	UTSW	10	107,790,649 (GRCm38)	missense	probably benign	0.02
R4064:Otogl	UTSW	10	107,790,649 (GRCm38)	missense	probably benign	0.02
R4108:Otogl	UTSW	10	107,771,244 (GRCm38)	missense	probably benign	0.01
R4352:Otogl	UTSW	10	107,869,535 (GRCm38)	missense	probably damaging	1.00
R4526:Otogl	UTSW	10	107,886,980 (GRCm38)	missense	probably damaging	1.00
R4614:Otogl	UTSW	10	107,892,124 (GRCm38)	nonsense	probably null
R4703:Otogl	UTSW	10	107,821,924 (GRCm38)	missense	probably damaging	1.00
R4741:Otogl	UTSW	10	107,779,260 (GRCm38)	missense	probably benign	0.00
R4790:Otogl	UTSW	10	107,822,033 (GRCm38)	critical splice acceptor site	probably null
R4802:Otogl	UTSW	10	107,901,336 (GRCm38)	missense	probably damaging	1.00
R4910:Otogl	UTSW	10	107,879,517 (GRCm38)	missense	probably benign	0.05
R4913:Otogl	UTSW	10	107,876,855 (GRCm38)	missense	probably damaging	0.98
R5238:Otogl	UTSW	10	107,768,973 (GRCm38)	missense	probably damaging	1.00
R5261:Otogl	UTSW	10	107,777,592 (GRCm38)	missense	probably benign	0.16
R5387:Otogl	UTSW	10	107,780,933 (GRCm38)	missense	probably benign	0.03
R5395:Otogl	UTSW	10	107,817,138 (GRCm38)	missense	probably benign	0.39
R5403:Otogl	UTSW	10	107,808,756 (GRCm38)	missense	probably benign	0.08
R5482:Otogl	UTSW	10	107,821,941 (GRCm38)	missense	probably damaging	0.99
R5547:Otogl	UTSW	10	107,782,048 (GRCm38)	missense	possibly damaging	0.55
R5611:Otogl	UTSW	10	107,786,769 (GRCm38)	missense	probably damaging	1.00
R5642:Otogl	UTSW	10	107,886,552 (GRCm38)	missense	probably benign	0.44
R5690:Otogl	UTSW	10	107,777,117 (GRCm38)	synonymous	silent
R5711:Otogl	UTSW	10	107,777,117 (GRCm38)	synonymous	silent
R5731:Otogl	UTSW	10	107,881,464 (GRCm38)	missense	probably damaging	0.98
R5743:Otogl	UTSW	10	107,857,001 (GRCm38)	missense	possibly damaging	0.67
R5782:Otogl	UTSW	10	107,777,117 (GRCm38)	synonymous	silent
R5820:Otogl	UTSW	10	107,777,117 (GRCm38)	synonymous	silent
R5897:Otogl	UTSW	10	107,777,117 (GRCm38)	synonymous	silent
R6004:Otogl	UTSW	10	107,879,529 (GRCm38)	missense	probably damaging	1.00
R6145:Otogl	UTSW	10	107,777,117 (GRCm38)	synonymous	silent
R6146:Otogl	UTSW	10	107,777,117 (GRCm38)	synonymous	silent
R6147:Otogl	UTSW	10	107,777,117 (GRCm38)	synonymous	silent
R6149:Otogl	UTSW	10	107,881,453 (GRCm38)	missense	probably benign	0.36
R6226:Otogl	UTSW	10	107,771,206 (GRCm38)	nonsense	probably null
R6283:Otogl	UTSW	10	107,790,500 (GRCm38)	missense	probably damaging	0.98
R6414:Otogl	UTSW	10	107,782,050 (GRCm38)	missense	probably damaging	1.00
R6604:Otogl	UTSW	10	107,822,034 (GRCm38)	splice site	probably null
R6634:Otogl	UTSW	10	107,862,304 (GRCm38)	missense	probably damaging	1.00
R6727:Otogl	UTSW	10	107,777,117 (GRCm38)	synonymous	silent
R6755:Otogl	UTSW	10	107,853,303 (GRCm38)	nonsense	probably null
R6795:Otogl	UTSW	10	107,777,117 (GRCm38)	synonymous	silent
R6797:Otogl	UTSW	10	107,777,117 (GRCm38)	synonymous	silent
R6864:Otogl	UTSW	10	107,827,806 (GRCm38)	missense	probably damaging	0.96
R6924:Otogl	UTSW	10	107,808,641 (GRCm38)	missense	probably damaging	1.00
R6967:Otogl	UTSW	10	107,814,050 (GRCm38)	missense	probably benign	0.01
R7000:Otogl	UTSW	10	107,779,831 (GRCm38)	missense	probably benign
R7075:Otogl	UTSW	10	107,778,929 (GRCm38)	missense	probably benign	0.16
R7122:Otogl	UTSW	10	107,866,654 (GRCm38)	missense	probably benign	0.08
R7176:Otogl	UTSW	10	107,778,911 (GRCm38)	missense	probably damaging	1.00
R7184:Otogl	UTSW	10	107,763,200 (GRCm38)	missense	probably damaging	1.00
R7199:Otogl	UTSW	10	107,874,533 (GRCm38)	missense	possibly damaging	0.88
R7252:Otogl	UTSW	10	107,821,943 (GRCm38)	missense	probably benign	0.06
R7286:Otogl	UTSW	10	107,770,610 (GRCm38)	missense	probably benign	0.00
R7373:Otogl	UTSW	10	107,901,251 (GRCm38)	missense	probably damaging	1.00
R7449:Otogl	UTSW	10	107,803,663 (GRCm38)	missense	probably damaging	1.00
R7486:Otogl	UTSW	10	107,821,988 (GRCm38)	missense	probably damaging	1.00
R7493:Otogl	UTSW	10	107,886,982 (GRCm38)	missense	probably benign	0.06
R7659:Otogl	UTSW	10	107,777,120 (GRCm38)	missense	probably benign	0.19
R7732:Otogl	UTSW	10	107,806,664 (GRCm38)	missense	probably benign	0.01
R7754:Otogl	UTSW	10	107,869,546 (GRCm38)	missense	probably damaging	0.99
R7757:Otogl	UTSW	10	107,876,921 (GRCm38)	missense	probably damaging	1.00
R7800:Otogl	UTSW	10	107,886,515 (GRCm38)	missense	probably damaging	0.99
R7864:Otogl	UTSW	10	107,869,567 (GRCm38)	missense	probably damaging	1.00
R7879:Otogl	UTSW	10	107,777,109 (GRCm38)	missense	probably benign	0.00
R7941:Otogl	UTSW	10	107,806,802 (GRCm38)	splice site	probably null
R7956:Otogl	UTSW	10	107,878,026 (GRCm38)	missense	possibly damaging	0.62
R7988:Otogl	UTSW	10	107,895,776 (GRCm38)	missense	probably damaging	1.00
R8057:Otogl	UTSW	10	107,808,615 (GRCm38)	missense	probably benign	0.00
R8058:Otogl	UTSW	10	107,762,426 (GRCm38)	missense	probably damaging	1.00
R8127:Otogl	UTSW	10	107,895,752 (GRCm38)	missense	probably damaging	1.00
R8143:Otogl	UTSW	10	107,806,666 (GRCm38)	missense	probably damaging	1.00
R8310:Otogl	UTSW	10	107,777,600 (GRCm38)	missense	possibly damaging	0.94
R8319:Otogl	UTSW	10	107,853,266 (GRCm38)	critical splice donor site	probably null
R8339:Otogl	UTSW	10	107,789,536 (GRCm38)	missense	probably benign	0.34
R8339:Otogl	UTSW	10	107,789,535 (GRCm38)	missense	probably damaging	0.99
R8394:Otogl	UTSW	10	107,886,465 (GRCm38)	critical splice donor site	probably null
R8428:Otogl	UTSW	10	107,798,736 (GRCm38)	missense	probably damaging	1.00
R8444:Otogl	UTSW	10	107,857,114 (GRCm38)	missense	probably benign	0.01
R8501:Otogl	UTSW	10	107,790,560 (GRCm38)	missense	probably benign
R8503:Otogl	UTSW	10	107,892,126 (GRCm38)	missense	probably damaging	1.00
R8680:Otogl	UTSW	10	107,912,075 (GRCm38)	critical splice donor site	probably null
R9025:Otogl	UTSW	10	107,777,571 (GRCm38)	missense	probably damaging	0.99
R9090:Otogl	UTSW	10	107,817,113 (GRCm38)	missense	probably null	0.99
R9223:Otogl	UTSW	10	107,854,344 (GRCm38)	missense	probably damaging	0.99
R9268:Otogl	UTSW	10	107,781,056 (GRCm38)	missense	probably damaging	1.00
R9271:Otogl	UTSW	10	107,817,113 (GRCm38)	missense	probably null	0.99
R9356:Otogl	UTSW	10	107,782,029 (GRCm38)	missense	probably damaging	1.00
R9484:Otogl	UTSW	10	107,901,295 (GRCm38)	missense	probably damaging	1.00
R9484:Otogl	UTSW	10	107,822,033 (GRCm38)	critical splice acceptor site	probably null
R9571:Otogl	UTSW	10	107,762,503 (GRCm38)	missense	possibly damaging	0.94
R9731:Otogl	UTSW	10	107,899,467 (GRCm38)	missense	probably damaging	1.00
X0065:Otogl	UTSW	10	107,895,782 (GRCm38)	missense	probably damaging	1.00
X0067:Otogl	UTSW	10	107,866,677 (GRCm38)	missense	probably damaging	1.00
Z1176:Otogl	UTSW	10	107,778,873 (GRCm38)	missense	probably damaging	0.97
Z1176:Otogl	UTSW	10	107,777,213 (GRCm38)	missense	probably benign
Z1176:Otogl	UTSW	10	107,789,032 (GRCm38)	missense	probably benign	0.00
Z1177:Otogl	UTSW	10	107,853,397 (GRCm38)	missense	possibly damaging	0.78
Z1177:Otogl	UTSW	10	107,763,258 (GRCm38)	nonsense	probably null
Z1177:Otogl	UTSW	10	107,876,903 (GRCm38)	missense	probably benign	0.14

Predicted Primers

Posted On

2017-04-14