Incidental Mutation 'R3699:Gm8229'
Institutional Source Beutler Lab
Gene Symbol Gm8229
Ensembl Gene ENSMUSG00000090379
Gene Namepredicted gene 8229
MMRRC Submission 040692-MU
Accession Numbers
Is this an essential gene? Possibly non essential (E-score: 0.470) question?
Stock #R3699 (G1)
Quality Score219
Status Not validated
Chromosomal Location44365357-44370841 bp(+) (GRCm38)
Type of Mutationmissense
DNA Base Change (assembly) T to A at 44366527 bp
Amino Acid Change Serine to Threonine at position 58 (S58T)
Gene Model predicted gene model for transcript(s):
Predicted Effect unknown
Transcript: ENSMUST00000168161
AA Change: S58T
SMART Domains Protein: ENSMUSP00000132728
Gene: ENSMUSG00000090379
AA Change: S58T

Pfam:Takusan 57 137 5.5e-28 PFAM
coiled coil region 164 186 N/A INTRINSIC
Coding Region Coverage
  • 1x: 99.1%
  • 3x: 98.6%
  • 10x: 97.2%
  • 20x: 94.8%
Validation Efficiency 100% (33/33)
Allele List at MGI
Other mutations in this stock
Total: 29 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
Ankrd29 G A 18: 12,254,700 A275V possibly damaging Het
Atp1b2 G A 11: 69,605,269 T35I probably benign Het
Baz1a A G 12: 54,917,046 V751A probably benign Het
Cdh23 C A 10: 60,327,370 probably null Het
Chd2 G T 7: 73,468,490 L1127I probably benign Het
D7Ertd443e A G 7: 134,349,068 L292P probably damaging Het
Dst T C 1: 34,213,074 probably benign Het
Gm13084 A G 4: 143,810,352 S470P probably benign Het
Gucy2c A T 6: 136,770,111 C117S probably damaging Het
Kirrel C T 3: 87,089,151 M380I probably null Het
Klhl18 A G 9: 110,436,066 Y291H probably benign Het
Lamc1 G T 1: 153,255,205 S333R possibly damaging Het
Lbr T C 1: 181,818,920 Y479C probably damaging Het
Nampt T C 12: 32,848,759 probably benign Het
Olfr1349 A G 7: 6,514,994 M145T probably damaging Het
Pcnx3 G T 19: 5,672,465 R1400S probably damaging Het
Pde4b C T 4: 102,601,545 A466V probably damaging Het
Piezo1 C T 8: 122,494,903 R584H probably damaging Het
Polq C A 16: 37,042,156 S338Y probably damaging Het
Rassf8 T C 6: 145,820,076 probably benign Het
Rere A T 4: 150,477,362 probably null Het
Rps6kb1 A G 11: 86,532,794 F120S probably damaging Het
Scarf1 G T 11: 75,514,369 C78F probably damaging Het
Tepsin C T 11: 120,091,753 C491Y possibly damaging Het
Trpv4 A G 5: 114,634,800 S243P probably damaging Het
Wdr60 C T 12: 116,211,842 W905* probably null Het
Whrn A T 4: 63,461,412 probably benign Het
Zfp521 G T 18: 13,846,273 S361* probably null Het
Zfyve19 A G 2: 119,211,239 T96A probably benign Het
Other mutations in Gm8229
AlleleSourceChrCoordTypePredicted EffectPPH Score
IGL02090:Gm8229 APN 14 44366597 missense unknown
IGL02609:Gm8229 APN 14 44366625 missense probably benign 0.09
R6444:Gm8229 UTSW 14 44365471 missense unknown
R7877:Gm8229 UTSW 14 44366576 nonsense probably null
Predicted Primers
Posted On2017-04-14