Incidental Mutation 'R3925:Olfr664'
ID474854
Institutional Source Beutler Lab
Gene Symbol Olfr664
Ensembl Gene ENSMUSG00000051885
Gene Nameolfactory receptor 664
SynonymsEG667918, MOR34-10P, GA_x6K02T2PBJ9-7361631-7360711
MMRRC Submission 040916-MU
Accession Numbers

Genbank: XM_890097; MGI: 3030498

Is this an essential gene? Probably non essential (E-score: 0.166) question?
Stock #R3925 (G1)
Quality Score225
Status Not validated
Chromosome7
Chromosomal Location104733385-104734350 bp(-) (GRCm38)
Type of Mutationmissense
DNA Base Change (assembly) T to A at 104734189 bp
ZygosityHeterozygous
Amino Acid Change Glutamic Acid to Aspartic acid at position 58 (E58D)
Ref Sequence ENSEMBL: ENSMUSP00000147645 (fasta)
Predicted Effect probably benign
Transcript: ENSMUST00000072887
AA Change: E54D

PolyPhen 2 Score 0.062 (Sensitivity: 0.94; Specificity: 0.84)
Predicted Effect probably benign
Transcript: ENSMUST00000211596
AA Change: E58D

PolyPhen 2 Score 0.072 (Sensitivity: 0.94; Specificity: 0.84)
Coding Region Coverage
  • 1x: 99.3%
  • 3x: 98.7%
  • 10x: 97.5%
  • 20x: 95.8%
Validation Efficiency 97% (30/31)
Allele List at MGI
Other mutations in this stock
Total: 31 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
Adgrv1 G A 13: 81,578,772 T487I possibly damaging Het
Amn T C 12: 111,275,680 V367A possibly damaging Het
C230029F24Rik AGAAAG A 1: 49,310,929 noncoding transcript Het
Cdkl1 G T 12: 69,756,599 R168S probably damaging Het
Cfap43 T C 19: 47,797,116 K445R probably benign Het
Crct1 C A 3: 93,014,707 probably benign Het
Eif4e G A 3: 138,555,437 G164D probably damaging Het
Eno1 T C 4: 150,239,568 probably null Het
Gm38100 T C 1: 175,921,286 V306A probably benign Het
Hmcn2 G A 2: 31,453,157 R4565Q probably benign Het
Itgal A T 7: 127,324,537 probably benign Het
Klhl1 A T 14: 96,346,880 C305S possibly damaging Het
Ms4a2 A G 19: 11,618,948 M139T probably benign Het
Nr2e3 C T 9: 59,948,433 R213H probably damaging Het
Olfr1102 A G 2: 87,002,374 Y135C possibly damaging Het
Olfr224 T A 11: 58,566,826 H173L probably benign Het
Onecut2 A G 18: 64,341,520 K381E probably damaging Het
Pabpc1l T A 2: 164,027,676 probably benign Het
Prim2 A G 1: 33,533,299 L253P probably damaging Het
Pycr1 T C 11: 120,642,135 T100A probably benign Het
Qrfpr T C 3: 36,221,923 N106S possibly damaging Het
Rsf1 GCG GCGACGGCGACG 7: 97,579,907 probably benign Het
Selenoi T A 5: 30,256,088 D107E probably damaging Het
Synrg C T 11: 84,040,899 P1321S probably benign Het
Tcrg-V7 A G 13: 19,178,474 Y111C probably damaging Het
Trp53rkb A G 2: 166,795,472 Y116C probably damaging Het
Usp34 T A 11: 23,343,640 F245I probably benign Het
Utrn C T 10: 12,698,042 V1095I probably benign Het
Xpnpep1 T C 19: 52,991,697 H632R probably damaging Het
Zfp735 T C 11: 73,711,124 I298T probably benign Het
Zfp953 T A 13: 67,347,938 Y13F probably damaging Het
Other mutations in Olfr664
AlleleSourceChrCoordTypePredicted EffectPPH Score
A9681:Olfr664 UTSW 7 104734403 unclassified probably benign
R2862:Olfr664 UTSW 7 104734218 missense probably benign
R3923:Olfr664 UTSW 7 104734189 missense probably benign 0.07
R4327:Olfr664 UTSW 7 104733626 missense probably damaging 1.00
R6226:Olfr664 UTSW 7 104734036 missense probably damaging 0.98
R6370:Olfr664 UTSW 7 104733917 missense probably benign 0.03
R7283:Olfr664 UTSW 7 104733593 missense probably damaging 1.00
R7397:Olfr664 UTSW 7 104733608 missense possibly damaging 0.46
R7554:Olfr664 UTSW 7 104733867 missense probably benign
Predicted Primers
Posted On2017-04-14