Incidental Mutation 'R6005:Adgb'
| ID |
479431 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Adgb
|
| Ensembl Gene |
ENSMUSG00000050994 |
| Gene Name |
androglobin |
| Synonyms |
9130014G24Rik |
| MMRRC Submission |
044425-MU
|
| Accession Numbers |
|
| Essential gene? |
Non essential
(E-score: 0.000)
|
| Stock # |
R6005 (G1)
|
| Quality Score |
225.009 |
|
Status
|
Validated
|
| Chromosome |
10 |
| Chromosomal Location |
10211447-10348070 bp(-) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
C to T
at 10271096 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Arginine to Histidine
at position 849
(R849H)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000136386
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000045328]
[ENSMUST00000148816]
[ENSMUST00000172530]
[ENSMUST00000179956]
[ENSMUST00000208717]
|
| AlphaFold |
G3UZ78 |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000045328
|
| SMART Domains |
Protein: ENSMUSP00000045452
Gene: ENSMUSG00000050994
| Domain | Start | End | E-Value | Type |
|---|
|
Blast:CysPc
|
11 |
257 |
1e-165 |
BLAST |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000148816
|
| SMART Domains |
Protein: ENSMUSP00000133652
Gene: ENSMUSG00000050994
| Domain | Start | End | E-Value | Type |
|---|
|
Blast:CysPc
|
1 |
41 |
1e-19 |
BLAST |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000172530
AA Change: R847H
PolyPhen 2
Score 0.175 (Sensitivity: 0.92; Specificity: 0.87)
|
| SMART Domains |
Protein: ENSMUSP00000134378
Gene: ENSMUSG00000050994
AA Change: R847H
| Domain | Start | End | E-Value | Type |
|---|
|
CysPc
|
56 |
655 |
2.7e-2 |
SMART |
|
IQ
|
904 |
926 |
6.41e0 |
SMART |
|
low complexity region
|
1179 |
1190 |
N/A |
INTRINSIC |
|
low complexity region
|
1318 |
1335 |
N/A |
INTRINSIC |
|
coiled coil region
|
1534 |
1559 |
N/A |
INTRINSIC |
|
low complexity region
|
1616 |
1633 |
N/A |
INTRINSIC |
|
low complexity region
|
1649 |
1657 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000179956
AA Change: R849H
PolyPhen 2
Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)
|
| SMART Domains |
Protein: ENSMUSP00000136386
Gene: ENSMUSG00000050994
AA Change: R849H
| Domain | Start | End | E-Value | Type |
|---|
|
CysPc
|
56 |
657 |
5.36e-2 |
SMART |
|
IQ
|
906 |
928 |
6.41e0 |
SMART |
|
low complexity region
|
1181 |
1192 |
N/A |
INTRINSIC |
|
low complexity region
|
1321 |
1338 |
N/A |
INTRINSIC |
|
coiled coil region
|
1537 |
1562 |
N/A |
INTRINSIC |
|
low complexity region
|
1619 |
1636 |
N/A |
INTRINSIC |
|
low complexity region
|
1652 |
1660 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000208717
AA Change: R823H
PolyPhen 2
Score 0.358 (Sensitivity: 0.90; Specificity: 0.89)
|
| Meta Mutation Damage Score |
0.2094 |
| Coding Region Coverage |
- 1x: 99.9%
- 3x: 99.4%
- 10x: 97.2%
- 20x: 90.9%
|
| Validation Efficiency |
99% (79/80) |
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 81 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 7530416G11Rik |
A |
T |
15: 85,378,310 (GRCm39) |
I111N |
unknown |
Het |
| Ahnak |
T |
C |
19: 8,992,525 (GRCm39) |
V4603A |
possibly damaging |
Het |
| Ank1 |
A |
G |
8: 23,622,218 (GRCm39) |
D1589G |
probably damaging |
Het |
| Ankrd2 |
A |
G |
19: 42,028,554 (GRCm39) |
D70G |
probably damaging |
Het |
| Arid2 |
T |
C |
15: 96,268,853 (GRCm39) |
S989P |
probably benign |
Het |
| Bbs1 |
A |
T |
19: 4,953,823 (GRCm39) |
Y113* |
probably null |
Het |
| Bfsp2 |
T |
G |
9: 103,325,749 (GRCm39) |
K298T |
probably damaging |
Het |
| Bpi |
G |
A |
2: 158,104,400 (GRCm39) |
V168I |
possibly damaging |
Het |
| Cacna2d1 |
T |
C |
5: 16,566,819 (GRCm39) |
S921P |
probably damaging |
Het |
| Clec4d |
A |
C |
6: 123,244,118 (GRCm39) |
T76P |
probably damaging |
Het |
| Coq8b |
C |
T |
7: 26,956,750 (GRCm39) |
Q468* |
probably null |
Het |
| Dennd6b |
T |
C |
15: 89,072,371 (GRCm39) |
E248G |
possibly damaging |
Het |
| Ednra |
A |
G |
8: 78,401,556 (GRCm39) |
S245P |
possibly damaging |
Het |
| Epb41l4a |
C |
T |
18: 33,961,196 (GRCm39) |
C446Y |
probably benign |
Het |
| Fam221a |
A |
G |
6: 49,344,756 (GRCm39) |
|
probably benign |
Het |
| Fam229a |
T |
C |
4: 129,385,296 (GRCm39) |
S76P |
probably benign |
Het |
| Fryl |
C |
T |
5: 73,240,638 (GRCm39) |
D1321N |
probably damaging |
Het |
| Gata3os |
T |
C |
2: 9,887,638 (GRCm39) |
|
probably benign |
Het |
| Gli2 |
C |
T |
1: 118,769,794 (GRCm39) |
R586H |
probably damaging |
Het |
| Gm94 |
C |
T |
18: 43,925,862 (GRCm39) |
A16T |
possibly damaging |
Het |
| Gorasp2 |
T |
C |
2: 70,521,095 (GRCm39) |
V355A |
probably benign |
Het |
| Grid1 |
C |
A |
14: 35,045,369 (GRCm39) |
T404N |
probably damaging |
Het |
| Gtf2i |
C |
A |
5: 134,284,812 (GRCm39) |
E475* |
probably null |
Het |
| Gucy1a2 |
T |
C |
9: 3,865,518 (GRCm39) |
|
probably null |
Het |
| Hs3st5 |
T |
A |
10: 36,708,924 (GRCm39) |
I153N |
probably damaging |
Het |
| Il11ra1 |
T |
C |
4: 41,763,887 (GRCm39) |
|
probably null |
Het |
| Ireb2 |
G |
A |
9: 54,816,089 (GRCm39) |
G887S |
probably damaging |
Het |
| Kdsr |
T |
C |
1: 106,662,311 (GRCm39) |
E248G |
probably benign |
Het |
| Lemd2 |
C |
G |
17: 27,409,759 (GRCm39) |
R464P |
probably damaging |
Het |
| Lrrfip1 |
T |
C |
1: 91,042,333 (GRCm39) |
V246A |
probably damaging |
Het |
| Macf1 |
T |
A |
4: 123,368,068 (GRCm39) |
D2231V |
possibly damaging |
Het |
| Map2k5 |
C |
T |
9: 63,188,301 (GRCm39) |
D283N |
probably damaging |
Het |
| Mfsd5 |
A |
G |
15: 102,189,927 (GRCm39) |
D433G |
possibly damaging |
Het |
| Mir700 |
C |
A |
4: 135,139,618 (GRCm39) |
|
probably null |
Het |
| Mroh9 |
A |
T |
1: 162,903,246 (GRCm39) |
F52L |
probably damaging |
Het |
| Mtrfr |
G |
T |
5: 124,478,837 (GRCm39) |
E153* |
probably null |
Het |
| Mycbp2 |
A |
C |
14: 103,394,159 (GRCm39) |
S2691A |
probably benign |
Het |
| Myorg |
T |
A |
4: 41,498,895 (GRCm39) |
H245L |
probably benign |
Het |
| Nktr |
T |
A |
9: 121,577,460 (GRCm39) |
|
probably benign |
Het |
| Obsl1 |
C |
A |
1: 75,468,859 (GRCm39) |
|
probably null |
Het |
| Or10ag60 |
A |
T |
2: 87,438,424 (GRCm39) |
I231F |
probably damaging |
Het |
| Or52r1b |
A |
T |
7: 102,690,853 (GRCm39) |
I51F |
probably damaging |
Het |
| Or5aq7 |
A |
G |
2: 86,938,407 (GRCm39) |
V108A |
probably benign |
Het |
| Or7g35 |
C |
T |
9: 19,496,181 (GRCm39) |
T116I |
probably benign |
Het |
| Or8c11 |
T |
C |
9: 38,289,605 (GRCm39) |
S137P |
probably damaging |
Het |
| Pcdhb22 |
T |
A |
18: 37,652,789 (GRCm39) |
I162N |
possibly damaging |
Het |
| Pde1c |
A |
T |
6: 56,456,187 (GRCm39) |
|
probably null |
Het |
| Pds5b |
A |
G |
5: 150,693,241 (GRCm39) |
|
probably null |
Het |
| Pkd1l1 |
A |
C |
11: 8,807,113 (GRCm39) |
W1568G |
probably damaging |
Het |
| Polr3c |
A |
T |
3: 96,626,784 (GRCm39) |
M258K |
possibly damaging |
Het |
| Pramel23 |
T |
A |
4: 143,425,002 (GRCm39) |
H147L |
probably benign |
Het |
| Prss12 |
A |
T |
3: 123,276,417 (GRCm39) |
I349F |
probably benign |
Het |
| Ptpn21 |
A |
G |
12: 98,644,811 (GRCm39) |
*1177Q |
probably null |
Het |
| Rgs22 |
T |
A |
15: 36,010,713 (GRCm39) |
K1125M |
probably benign |
Het |
| Rnf182 |
A |
G |
13: 43,821,511 (GRCm39) |
K21E |
probably damaging |
Het |
| Rpl6 |
G |
A |
5: 121,343,577 (GRCm39) |
|
probably benign |
Het |
| Samsn1 |
C |
T |
16: 75,670,402 (GRCm39) |
V234I |
probably benign |
Het |
| Scrib |
A |
G |
15: 75,929,600 (GRCm39) |
I1089T |
probably damaging |
Het |
| Sec31a |
T |
C |
5: 100,511,737 (GRCm39) |
T1092A |
probably damaging |
Het |
| Sh3bp2 |
G |
T |
5: 34,719,809 (GRCm39) |
R606L |
possibly damaging |
Het |
| Sipa1 |
A |
G |
19: 5,706,229 (GRCm39) |
V367A |
probably damaging |
Het |
| Slc25a44 |
C |
T |
3: 88,320,153 (GRCm39) |
E269K |
probably damaging |
Het |
| Slc44a4 |
T |
A |
17: 35,142,430 (GRCm39) |
M353K |
possibly damaging |
Het |
| Sorcs2 |
A |
G |
5: 36,176,728 (GRCm39) |
S1142P |
probably damaging |
Het |
| Sptbn4 |
A |
G |
7: 27,118,024 (GRCm39) |
F352L |
probably damaging |
Het |
| Synj1 |
A |
T |
16: 90,766,174 (GRCm39) |
N541K |
probably damaging |
Het |
| Tas2r113 |
G |
A |
6: 132,870,659 (GRCm39) |
R229K |
probably benign |
Het |
| Tcaf3 |
A |
T |
6: 42,566,905 (GRCm39) |
I728K |
probably benign |
Het |
| Tcea1 |
A |
G |
1: 4,960,996 (GRCm39) |
E167G |
probably benign |
Het |
| Timeless |
G |
A |
10: 128,080,069 (GRCm39) |
R406H |
probably damaging |
Het |
| Traf6 |
C |
T |
2: 101,527,029 (GRCm39) |
R260* |
probably null |
Het |
| Traj31 |
C |
T |
14: 54,425,388 (GRCm39) |
|
probably benign |
Het |
| Ttn |
A |
T |
2: 76,599,907 (GRCm39) |
V19089D |
probably damaging |
Het |
| Unc80 |
C |
T |
1: 66,666,416 (GRCm39) |
S1868L |
possibly damaging |
Het |
| Wdr38 |
A |
T |
2: 38,891,333 (GRCm39) |
I287F |
possibly damaging |
Het |
| Wnt2 |
G |
A |
6: 18,030,322 (GRCm39) |
|
probably benign |
Het |
| Wnt5b |
G |
A |
6: 119,410,615 (GRCm39) |
P288L |
probably benign |
Het |
| Xkr5 |
G |
T |
8: 18,984,521 (GRCm39) |
N174K |
probably benign |
Het |
| Zbtb6 |
C |
T |
2: 37,318,977 (GRCm39) |
R317Q |
probably damaging |
Het |
| Zcchc7 |
AGGGG |
AGGG |
4: 44,931,218 (GRCm39) |
|
probably null |
Het |
| Zfp647 |
G |
A |
15: 76,796,285 (GRCm39) |
P125L |
probably damaging |
Het |
|
| Other mutations in Adgb |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00503:Adgb
|
APN |
10 |
10,281,843 (GRCm39) |
missense |
possibly damaging |
0.87 |
|
IGL01083:Adgb
|
APN |
10 |
10,283,298 (GRCm39) |
missense |
possibly damaging |
0.50 |
|
IGL03064:Adgb
|
APN |
10 |
10,276,316 (GRCm39) |
missense |
probably benign |
0.02 |
|
R0080:Adgb
|
UTSW |
10 |
10,253,583 (GRCm39) |
splice site |
probably benign |
|
|
R0084:Adgb
|
UTSW |
10 |
10,272,088 (GRCm39) |
missense |
possibly damaging |
0.74 |
|
R0112:Adgb
|
UTSW |
10 |
10,282,902 (GRCm39) |
splice site |
probably benign |
|
|
R0348:Adgb
|
UTSW |
10 |
10,233,623 (GRCm39) |
missense |
probably benign |
|
|
R0415:Adgb
|
UTSW |
10 |
10,306,811 (GRCm39) |
splice site |
probably null |
|
|
R0633:Adgb
|
UTSW |
10 |
10,267,473 (GRCm39) |
missense |
probably benign |
0.36 |
|
R1052:Adgb
|
UTSW |
10 |
10,318,357 (GRCm39) |
missense |
probably benign |
0.29 |
|
R1248:Adgb
|
UTSW |
10 |
10,271,054 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R1278:Adgb
|
UTSW |
10 |
10,258,572 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1568:Adgb
|
UTSW |
10 |
10,318,409 (GRCm39) |
nonsense |
probably null |
|
|
R1647:Adgb
|
UTSW |
10 |
10,271,115 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1648:Adgb
|
UTSW |
10 |
10,271,115 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1663:Adgb
|
UTSW |
10 |
10,215,419 (GRCm39) |
missense |
possibly damaging |
0.86 |
|
R1688:Adgb
|
UTSW |
10 |
10,226,061 (GRCm39) |
nonsense |
probably null |
|
|
R1758:Adgb
|
UTSW |
10 |
10,302,349 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1772:Adgb
|
UTSW |
10 |
10,258,465 (GRCm39) |
splice site |
probably benign |
|
|
R1850:Adgb
|
UTSW |
10 |
10,318,246 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1959:Adgb
|
UTSW |
10 |
10,270,993 (GRCm39) |
missense |
probably benign |
0.02 |
|
R1980:Adgb
|
UTSW |
10 |
10,309,242 (GRCm39) |
missense |
probably benign |
|
|
R2179:Adgb
|
UTSW |
10 |
10,271,018 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R2229:Adgb
|
UTSW |
10 |
10,311,795 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2283:Adgb
|
UTSW |
10 |
10,253,635 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R2870:Adgb
|
UTSW |
10 |
10,307,025 (GRCm39) |
critical splice donor site |
probably null |
|
|
R2870:Adgb
|
UTSW |
10 |
10,307,025 (GRCm39) |
critical splice donor site |
probably null |
|
|
R2875:Adgb
|
UTSW |
10 |
10,298,463 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2876:Adgb
|
UTSW |
10 |
10,298,463 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2920:Adgb
|
UTSW |
10 |
10,265,987 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2931:Adgb
|
UTSW |
10 |
10,318,246 (GRCm39) |
missense |
possibly damaging |
0.84 |
|
R3722:Adgb
|
UTSW |
10 |
10,216,254 (GRCm39) |
missense |
probably benign |
0.32 |
|
R3846:Adgb
|
UTSW |
10 |
10,258,465 (GRCm39) |
splice site |
probably benign |
|
|
R3877:Adgb
|
UTSW |
10 |
10,318,227 (GRCm39) |
critical splice donor site |
probably null |
|
|
R4210:Adgb
|
UTSW |
10 |
10,283,209 (GRCm39) |
missense |
probably benign |
0.06 |
|
R4211:Adgb
|
UTSW |
10 |
10,283,209 (GRCm39) |
missense |
probably benign |
0.06 |
|
R4333:Adgb
|
UTSW |
10 |
10,318,246 (GRCm39) |
missense |
possibly damaging |
0.84 |
|
R4448:Adgb
|
UTSW |
10 |
10,266,569 (GRCm39) |
missense |
probably benign |
0.32 |
|
R4470:Adgb
|
UTSW |
10 |
10,274,695 (GRCm39) |
missense |
probably benign |
0.02 |
|
R4624:Adgb
|
UTSW |
10 |
10,278,748 (GRCm39) |
missense |
probably benign |
0.00 |
|
R4656:Adgb
|
UTSW |
10 |
10,281,050 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R4676:Adgb
|
UTSW |
10 |
10,302,454 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4792:Adgb
|
UTSW |
10 |
10,274,647 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R4795:Adgb
|
UTSW |
10 |
10,233,616 (GRCm39) |
missense |
probably benign |
0.01 |
|
R4858:Adgb
|
UTSW |
10 |
10,225,321 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4985:Adgb
|
UTSW |
10 |
10,276,376 (GRCm39) |
missense |
possibly damaging |
0.69 |
|
R5057:Adgb
|
UTSW |
10 |
10,233,722 (GRCm39) |
missense |
probably benign |
0.11 |
|
R5157:Adgb
|
UTSW |
10 |
10,274,710 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5209:Adgb
|
UTSW |
10 |
10,274,681 (GRCm39) |
missense |
possibly damaging |
0.71 |
|
R5339:Adgb
|
UTSW |
10 |
10,318,350 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5376:Adgb
|
UTSW |
10 |
10,222,307 (GRCm39) |
missense |
probably benign |
0.09 |
|
R5426:Adgb
|
UTSW |
10 |
10,226,004 (GRCm39) |
missense |
probably benign |
0.14 |
|
R5516:Adgb
|
UTSW |
10 |
10,306,901 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5554:Adgb
|
UTSW |
10 |
10,216,217 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R5678:Adgb
|
UTSW |
10 |
10,307,070 (GRCm39) |
missense |
possibly damaging |
0.83 |
|
R5707:Adgb
|
UTSW |
10 |
10,267,501 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5708:Adgb
|
UTSW |
10 |
10,267,501 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5891:Adgb
|
UTSW |
10 |
10,253,591 (GRCm39) |
nonsense |
probably null |
|
|
R5928:Adgb
|
UTSW |
10 |
10,254,531 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6017:Adgb
|
UTSW |
10 |
10,325,780 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6049:Adgb
|
UTSW |
10 |
10,253,770 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6118:Adgb
|
UTSW |
10 |
10,307,035 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6175:Adgb
|
UTSW |
10 |
10,274,687 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R6186:Adgb
|
UTSW |
10 |
10,298,502 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6234:Adgb
|
UTSW |
10 |
10,228,824 (GRCm39) |
splice site |
probably null |
|
|
R6383:Adgb
|
UTSW |
10 |
10,325,772 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6522:Adgb
|
UTSW |
10 |
10,253,636 (GRCm39) |
nonsense |
probably null |
|
|
R6639:Adgb
|
UTSW |
10 |
10,311,700 (GRCm39) |
missense |
possibly damaging |
0.51 |
|
R6697:Adgb
|
UTSW |
10 |
10,281,870 (GRCm39) |
nonsense |
probably null |
|
|
R6742:Adgb
|
UTSW |
10 |
10,287,593 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6745:Adgb
|
UTSW |
10 |
10,265,941 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6850:Adgb
|
UTSW |
10 |
10,270,318 (GRCm39) |
missense |
probably benign |
0.39 |
|
R7128:Adgb
|
UTSW |
10 |
10,347,985 (GRCm39) |
missense |
probably benign |
0.26 |
|
R7326:Adgb
|
UTSW |
10 |
10,276,318 (GRCm39) |
missense |
possibly damaging |
0.80 |
|
R7386:Adgb
|
UTSW |
10 |
10,253,693 (GRCm39) |
missense |
possibly damaging |
0.52 |
|
R7431:Adgb
|
UTSW |
10 |
10,267,699 (GRCm39) |
splice site |
probably null |
|
|
R7569:Adgb
|
UTSW |
10 |
10,306,996 (GRCm39) |
missense |
probably benign |
|
|
R7579:Adgb
|
UTSW |
10 |
10,286,562 (GRCm39) |
nonsense |
probably null |
|
|
R7582:Adgb
|
UTSW |
10 |
10,266,565 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7615:Adgb
|
UTSW |
10 |
10,311,754 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R7692:Adgb
|
UTSW |
10 |
10,287,456 (GRCm39) |
critical splice donor site |
probably null |
|
|
R7774:Adgb
|
UTSW |
10 |
10,215,404 (GRCm39) |
nonsense |
probably null |
|
|
R7808:Adgb
|
UTSW |
10 |
10,254,403 (GRCm39) |
splice site |
probably null |
|
|
R8158:Adgb
|
UTSW |
10 |
10,254,478 (GRCm39) |
missense |
probably benign |
0.22 |
|
R8386:Adgb
|
UTSW |
10 |
10,226,048 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8746:Adgb
|
UTSW |
10 |
10,281,028 (GRCm39) |
critical splice donor site |
probably null |
|
|
R8785:Adgb
|
UTSW |
10 |
10,233,710 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9089:Adgb
|
UTSW |
10 |
10,318,432 (GRCm39) |
missense |
probably benign |
0.26 |
|
R9140:Adgb
|
UTSW |
10 |
10,216,263 (GRCm39) |
nonsense |
probably null |
|
|
R9386:Adgb
|
UTSW |
10 |
10,274,708 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9777:Adgb
|
UTSW |
10 |
10,283,214 (GRCm39) |
missense |
possibly damaging |
0.74 |
|
X0003:Adgb
|
UTSW |
10 |
10,270,374 (GRCm39) |
missense |
possibly damaging |
0.76 |
|
Z1176:Adgb
|
UTSW |
10 |
10,254,486 (GRCm39) |
missense |
probably benign |
0.09 |
|
| Predicted Primers |
PCR Primer
(F):5'- TACACAAGAGCTGAGCACAG -3'
(R):5'- GAATTGGCAATGACAAATGTCCAC -3'
Sequencing Primer
(F):5'- CTGAGCACAGCCATTTTAAATTACC -3'
(R):5'- TGGCAATGACAAATGTCCACCTTATC -3'
|
| Posted On |
2017-06-26 |
Incidental Mutation