Incidental Mutation 'R0514:Magi3'
| ID |
48084 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Magi3
|
| Ensembl Gene |
ENSMUSG00000052539 |
| Gene Name |
membrane associated guanylate kinase, WW and PDZ domain containing 3 |
| Synonyms |
4732496O19Rik, 6530407C02Rik |
| MMRRC Submission |
038708-MU
|
| Accession Numbers |
|
| Essential gene? |
Possibly non essential
(E-score: 0.435)
|
| Stock # |
R0514 (G1)
|
| Quality Score |
225 |
|
Status
|
Not validated
|
| Chromosome |
3 |
| Chromosomal Location |
103920575-104127690 bp(-) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
G to A
at 103922338 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Proline to Serine
at position 1460
(P1460S)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000112934
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000064371]
[ENSMUST00000121198]
[ENSMUST00000122303]
[ENSMUST00000145727]
|
| AlphaFold |
no structure available at present |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000064371
|
| SMART Domains |
Protein: ENSMUSP00000067932
Gene: ENSMUSG00000052539
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
2 |
14 |
N/A |
INTRINSIC |
|
PDZ
|
27 |
108 |
1.94e-1 |
SMART |
|
GuKc
|
114 |
281 |
8.56e-10 |
SMART |
|
WW
|
297 |
329 |
9.14e-12 |
SMART |
|
WW
|
343 |
375 |
2.47e-8 |
SMART |
|
PDZ
|
421 |
497 |
1.48e-17 |
SMART |
|
PDZ
|
589 |
659 |
3.07e-10 |
SMART |
|
low complexity region
|
664 |
674 |
N/A |
INTRINSIC |
|
low complexity region
|
683 |
698 |
N/A |
INTRINSIC |
|
PDZ
|
737 |
813 |
1.34e-15 |
SMART |
|
PDZ
|
861 |
939 |
7.65e-20 |
SMART |
|
PDZ
|
1030 |
1104 |
1.55e-20 |
SMART |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000121198
AA Change: P1460S
PolyPhen 2
Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)
|
| SMART Domains |
Protein: ENSMUSP00000112934
Gene: ENSMUSG00000052539
AA Change: P1460S
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
2 |
14 |
N/A |
INTRINSIC |
|
PDZ
|
27 |
108 |
1.94e-1 |
SMART |
|
GuKc
|
114 |
281 |
8.56e-10 |
SMART |
|
WW
|
297 |
329 |
9.14e-12 |
SMART |
|
WW
|
343 |
375 |
2.47e-8 |
SMART |
|
PDZ
|
421 |
497 |
1.48e-17 |
SMART |
|
PDZ
|
589 |
659 |
3.07e-10 |
SMART |
|
low complexity region
|
664 |
674 |
N/A |
INTRINSIC |
|
low complexity region
|
683 |
698 |
N/A |
INTRINSIC |
|
PDZ
|
737 |
813 |
1.34e-15 |
SMART |
|
PDZ
|
861 |
939 |
7.65e-20 |
SMART |
|
PDZ
|
1030 |
1104 |
1.55e-20 |
SMART |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000122303
|
| SMART Domains |
Protein: ENSMUSP00000113713
Gene: ENSMUSG00000052539
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
2 |
14 |
N/A |
INTRINSIC |
|
PDZ
|
27 |
108 |
1.94e-1 |
SMART |
|
GuKc
|
114 |
281 |
8.56e-10 |
SMART |
|
WW
|
297 |
329 |
9.14e-12 |
SMART |
|
WW
|
343 |
375 |
2.47e-8 |
SMART |
|
PDZ
|
421 |
497 |
1.48e-17 |
SMART |
|
PDZ
|
589 |
659 |
3.07e-10 |
SMART |
|
low complexity region
|
664 |
674 |
N/A |
INTRINSIC |
|
low complexity region
|
683 |
698 |
N/A |
INTRINSIC |
|
PDZ
|
737 |
813 |
1.34e-15 |
SMART |
|
PDZ
|
861 |
939 |
7.65e-20 |
SMART |
|
PDZ
|
1030 |
1104 |
1.55e-20 |
SMART |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000145727
|
| SMART Domains |
Protein: ENSMUSP00000114722
Gene: ENSMUSG00000058388
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:Phtf-FEM1B_bdg
|
3 |
158 |
1.6e-88 |
PFAM |
|
low complexity region
|
170 |
181 |
N/A |
INTRINSIC |
|
low complexity region
|
347 |
370 |
N/A |
INTRINSIC |
|
transmembrane domain
|
473 |
492 |
N/A |
INTRINSIC |
|
transmembrane domain
|
512 |
534 |
N/A |
INTRINSIC |
|
transmembrane domain
|
610 |
632 |
N/A |
INTRINSIC |
|
transmembrane domain
|
647 |
664 |
N/A |
INTRINSIC |
|
| Coding Region Coverage |
- 1x: 99.2%
- 3x: 98.5%
- 10x: 96.8%
- 20x: 94.1%
|
| Validation Efficiency |
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 91 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Acp3 |
T |
A |
9: 104,197,177 (GRCm39) |
Y154F |
probably damaging |
Het |
| Acsl6 |
A |
T |
11: 54,241,406 (GRCm39) |
D579V |
probably damaging |
Het |
| Adamts18 |
C |
T |
8: 114,465,401 (GRCm39) |
|
probably null |
Het |
| Adamts20 |
A |
T |
15: 94,168,257 (GRCm39) |
V1882D |
probably damaging |
Het |
| Add3 |
A |
T |
19: 53,225,274 (GRCm39) |
K465* |
probably null |
Het |
| Ago1 |
T |
G |
4: 126,333,388 (GRCm39) |
I524L |
probably benign |
Het |
| Akr1c18 |
A |
G |
13: 4,187,190 (GRCm39) |
M208T |
probably benign |
Het |
| Anapc1 |
C |
A |
2: 128,474,575 (GRCm39) |
L1413F |
probably damaging |
Het |
| Arid4b |
A |
T |
13: 14,358,902 (GRCm39) |
D646V |
probably damaging |
Het |
| Arnt2 |
T |
C |
7: 83,954,067 (GRCm39) |
E261G |
probably benign |
Het |
| Bccip |
C |
T |
7: 133,320,859 (GRCm39) |
T211I |
possibly damaging |
Het |
| Bsn |
T |
C |
9: 108,002,981 (GRCm39) |
S475G |
probably benign |
Het |
| Cdh26 |
G |
A |
2: 178,108,621 (GRCm39) |
|
probably null |
Het |
| Ceacam2 |
A |
G |
7: 25,220,356 (GRCm39) |
F414S |
probably benign |
Het |
| Cep43 |
A |
G |
17: 8,410,266 (GRCm39) |
N342S |
possibly damaging |
Het |
| Cfb |
T |
C |
17: 35,079,874 (GRCm39) |
R172G |
probably damaging |
Het |
| Cntnap5b |
A |
C |
1: 99,700,511 (GRCm39) |
T8P |
probably benign |
Het |
| Cpne9 |
A |
T |
6: 113,266,974 (GRCm39) |
I136L |
probably damaging |
Het |
| Crtc1 |
A |
T |
8: 70,855,079 (GRCm39) |
|
probably null |
Het |
| Dcdc2a |
A |
T |
13: 25,303,369 (GRCm39) |
H300L |
probably benign |
Het |
| Dhdh |
C |
T |
7: 45,138,130 (GRCm39) |
V20M |
probably benign |
Het |
| Dhx34 |
T |
C |
7: 15,944,462 (GRCm39) |
Q584R |
probably benign |
Het |
| Dis3l2 |
A |
G |
1: 86,974,814 (GRCm39) |
Y701C |
probably damaging |
Het |
| Dmrt2 |
T |
C |
19: 25,653,019 (GRCm39) |
|
probably null |
Het |
| Dnah5 |
A |
G |
15: 28,366,467 (GRCm39) |
T2727A |
probably damaging |
Het |
| Dop1a |
A |
G |
9: 86,402,787 (GRCm39) |
E1329G |
probably damaging |
Het |
| Evpl |
A |
G |
11: 116,114,117 (GRCm39) |
V1191A |
probably damaging |
Het |
| Fhl4 |
T |
C |
10: 84,934,250 (GRCm39) |
D177G |
probably damaging |
Het |
| Gask1a |
A |
G |
9: 121,807,418 (GRCm39) |
T521A |
possibly damaging |
Het |
| Heg1 |
A |
G |
16: 33,547,126 (GRCm39) |
T662A |
possibly damaging |
Het |
| Ifih1 |
A |
G |
2: 62,453,735 (GRCm39) |
|
probably null |
Het |
| Il13 |
T |
C |
11: 53,523,345 (GRCm39) |
R87G |
possibly damaging |
Het |
| Kcnc3 |
T |
A |
7: 44,245,352 (GRCm39) |
Y547* |
probably null |
Het |
| Krt81 |
C |
A |
15: 101,361,508 (GRCm39) |
R24L |
possibly damaging |
Het |
| Lama1 |
G |
A |
17: 68,071,693 (GRCm39) |
G860D |
probably benign |
Het |
| Lmo7 |
T |
C |
14: 102,124,609 (GRCm39) |
L356P |
probably damaging |
Het |
| Lmo7 |
A |
T |
14: 102,133,995 (GRCm39) |
K447I |
probably damaging |
Het |
| Lrp2bp |
A |
G |
8: 46,464,995 (GRCm39) |
H38R |
probably damaging |
Het |
| Megf8 |
T |
A |
7: 25,063,728 (GRCm39) |
C2695S |
possibly damaging |
Het |
| Mrgprb2 |
T |
G |
7: 48,201,718 (GRCm39) |
S336R |
probably benign |
Het |
| Mrgprx2 |
C |
T |
7: 48,132,712 (GRCm39) |
M1I |
probably null |
Het |
| Mug2 |
T |
C |
6: 122,058,558 (GRCm39) |
L1320P |
probably damaging |
Het |
| Noxred1 |
A |
G |
12: 87,273,838 (GRCm39) |
S68P |
probably benign |
Het |
| Or51f5 |
T |
A |
7: 102,424,539 (GRCm39) |
H269Q |
probably benign |
Het |
| Or56b1b |
T |
A |
7: 108,164,879 (GRCm39) |
Y41F |
probably damaging |
Het |
| Os9 |
C |
T |
10: 126,955,508 (GRCm39) |
C123Y |
probably damaging |
Het |
| Ostf1 |
T |
A |
19: 18,573,723 (GRCm39) |
T42S |
probably benign |
Het |
| Parg |
C |
A |
14: 31,976,517 (GRCm39) |
T186K |
possibly damaging |
Het |
| Pcnx1 |
T |
A |
12: 82,041,884 (GRCm39) |
M2172K |
probably benign |
Het |
| Pip4k2a |
A |
G |
2: 18,850,747 (GRCm39) |
I360T |
probably damaging |
Het |
| Pkn2 |
T |
C |
3: 142,516,219 (GRCm39) |
D568G |
possibly damaging |
Het |
| Plch2 |
A |
G |
4: 155,083,343 (GRCm39) |
S431P |
probably damaging |
Het |
| Prl8a6 |
A |
T |
13: 27,616,990 (GRCm39) |
C233* |
probably null |
Het |
| Prox1 |
G |
A |
1: 189,893,653 (GRCm39) |
T264I |
probably damaging |
Het |
| Prr5 |
A |
G |
15: 84,586,967 (GRCm39) |
N248S |
probably benign |
Het |
| Psip1 |
A |
C |
4: 83,378,274 (GRCm39) |
S407R |
probably damaging |
Het |
| Rab32 |
A |
T |
10: 10,426,640 (GRCm39) |
V102E |
probably damaging |
Het |
| Rap1gap2 |
T |
G |
11: 74,279,680 (GRCm39) |
K687Q |
possibly damaging |
Het |
| Rbak |
A |
T |
5: 143,159,169 (GRCm39) |
V628E |
probably damaging |
Het |
| Rnf148 |
T |
C |
6: 23,654,792 (GRCm39) |
E68G |
possibly damaging |
Het |
| Rnf212 |
A |
T |
5: 108,897,308 (GRCm39) |
S3T |
probably damaging |
Het |
| Rrad |
T |
G |
8: 105,355,259 (GRCm39) |
I250L |
probably benign |
Het |
| Sall4 |
T |
C |
2: 168,597,625 (GRCm39) |
H405R |
probably damaging |
Het |
| Scn9a |
T |
C |
2: 66,314,022 (GRCm39) |
R1888G |
probably damaging |
Het |
| Setd5 |
G |
T |
6: 113,096,398 (GRCm39) |
E535* |
probably null |
Het |
| Slc20a1 |
C |
T |
2: 129,041,811 (GRCm39) |
S58L |
probably damaging |
Het |
| Slc31a1 |
A |
G |
4: 62,303,841 (GRCm39) |
|
probably benign |
Het |
| Slc38a11 |
G |
T |
2: 65,147,209 (GRCm39) |
Q423K |
probably benign |
Het |
| Snrpd1 |
A |
T |
18: 10,626,846 (GRCm39) |
T38S |
possibly damaging |
Het |
| Taar4 |
A |
G |
10: 23,836,780 (GRCm39) |
D130G |
probably damaging |
Het |
| Tfb2m |
C |
T |
1: 179,358,869 (GRCm39) |
R338H |
probably benign |
Het |
| Tm2d2 |
A |
G |
8: 25,512,742 (GRCm39) |
I197V |
possibly damaging |
Het |
| Tmem132a |
C |
T |
19: 10,836,355 (GRCm39) |
G725D |
probably damaging |
Het |
| Tmem67 |
T |
C |
4: 12,089,317 (GRCm39) |
T38A |
probably benign |
Het |
| Tmprss15 |
A |
T |
16: 78,765,155 (GRCm39) |
S816T |
probably benign |
Het |
| Tnfrsf11a |
A |
G |
1: 105,754,717 (GRCm39) |
E263G |
probably damaging |
Het |
| Tnfrsf17 |
C |
T |
16: 11,133,191 (GRCm39) |
L90F |
probably benign |
Het |
| Tpr |
A |
G |
1: 150,278,024 (GRCm39) |
K117E |
possibly damaging |
Het |
| Trim43a |
C |
T |
9: 88,466,389 (GRCm39) |
Q5* |
probably null |
Het |
| Ubn1 |
A |
T |
16: 4,890,935 (GRCm39) |
D498V |
probably damaging |
Het |
| Vipr1 |
T |
A |
9: 121,487,115 (GRCm39) |
C63S |
probably damaging |
Het |
| Vmn1r237 |
T |
A |
17: 21,534,932 (GRCm39) |
H218Q |
possibly damaging |
Het |
| Vmn2r100 |
C |
A |
17: 19,742,382 (GRCm39) |
P252Q |
possibly damaging |
Het |
| Vmn2r95 |
T |
C |
17: 18,671,844 (GRCm39) |
V527A |
probably benign |
Het |
| Vmn2r97 |
A |
T |
17: 19,134,734 (GRCm39) |
T51S |
probably benign |
Het |
| Vwa8 |
G |
A |
14: 79,184,629 (GRCm39) |
V376I |
probably benign |
Het |
| Wdfy4 |
T |
A |
14: 32,802,732 (GRCm39) |
T1838S |
probably benign |
Het |
| Zcwpw1 |
A |
T |
5: 137,794,945 (GRCm39) |
E47V |
probably benign |
Het |
| Zeb2 |
T |
C |
2: 44,892,659 (GRCm39) |
E130G |
possibly damaging |
Het |
| Zfp111 |
A |
G |
7: 23,898,568 (GRCm39) |
Y348H |
probably damaging |
Het |
| Zfp53 |
T |
C |
17: 21,729,271 (GRCm39) |
S435P |
probably damaging |
Het |
|
| Other mutations in Magi3 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00429:Magi3
|
APN |
3 |
103,922,294 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL00933:Magi3
|
APN |
3 |
103,923,163 (GRCm39) |
missense |
probably benign |
|
|
IGL01151:Magi3
|
APN |
3 |
103,958,690 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01674:Magi3
|
APN |
3 |
104,013,037 (GRCm39) |
splice site |
probably benign |
|
|
IGL01790:Magi3
|
APN |
3 |
103,992,560 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01903:Magi3
|
APN |
3 |
103,958,526 (GRCm39) |
missense |
possibly damaging |
0.87 |
|
IGL01939:Magi3
|
APN |
3 |
103,961,778 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL02142:Magi3
|
APN |
3 |
103,923,219 (GRCm39) |
missense |
probably benign |
0.32 |
|
IGL02183:Magi3
|
APN |
3 |
103,992,663 (GRCm39) |
missense |
probably benign |
0.01 |
|
IGL02887:Magi3
|
APN |
3 |
104,002,473 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03071:Magi3
|
APN |
3 |
103,923,202 (GRCm39) |
missense |
possibly damaging |
0.51 |
|
IGL03085:Magi3
|
APN |
3 |
103,922,655 (GRCm39) |
missense |
possibly damaging |
0.88 |
|
IGL03192:Magi3
|
APN |
3 |
103,950,562 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03204:Magi3
|
APN |
3 |
104,013,151 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03227:Magi3
|
APN |
3 |
103,958,435 (GRCm39) |
missense |
probably benign |
|
|
IGL03388:Magi3
|
APN |
3 |
103,923,157 (GRCm39) |
missense |
probably benign |
0.30 |
|
PIT4280001:Magi3
|
UTSW |
3 |
103,961,668 (GRCm39) |
missense |
probably damaging |
1.00 |
|
PIT4504001:Magi3
|
UTSW |
3 |
103,922,842 (GRCm39) |
missense |
probably benign |
0.05 |
|
R0092:Magi3
|
UTSW |
3 |
103,958,280 (GRCm39) |
nonsense |
probably null |
|
|
R0569:Magi3
|
UTSW |
3 |
103,923,358 (GRCm39) |
missense |
probably benign |
0.43 |
|
R0608:Magi3
|
UTSW |
3 |
103,924,873 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0920:Magi3
|
UTSW |
3 |
103,941,507 (GRCm39) |
splice site |
probably null |
|
|
R1173:Magi3
|
UTSW |
3 |
103,968,946 (GRCm39) |
critical splice donor site |
probably null |
|
|
R1256:Magi3
|
UTSW |
3 |
103,935,126 (GRCm39) |
missense |
probably benign |
0.08 |
|
R1391:Magi3
|
UTSW |
3 |
103,922,374 (GRCm39) |
nonsense |
probably null |
|
|
R1559:Magi3
|
UTSW |
3 |
103,954,169 (GRCm39) |
splice site |
probably benign |
|
|
R1568:Magi3
|
UTSW |
3 |
103,996,843 (GRCm39) |
missense |
probably benign |
0.02 |
|
R1631:Magi3
|
UTSW |
3 |
103,958,493 (GRCm39) |
missense |
probably benign |
0.05 |
|
R1747:Magi3
|
UTSW |
3 |
103,941,489 (GRCm39) |
missense |
possibly damaging |
0.82 |
|
R1930:Magi3
|
UTSW |
3 |
103,996,920 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1964:Magi3
|
UTSW |
3 |
103,927,718 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R2151:Magi3
|
UTSW |
3 |
103,992,554 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2151:Magi3
|
UTSW |
3 |
103,954,198 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2266:Magi3
|
UTSW |
3 |
103,928,382 (GRCm39) |
intron |
probably benign |
|
|
R2267:Magi3
|
UTSW |
3 |
103,928,382 (GRCm39) |
intron |
probably benign |
|
|
R2268:Magi3
|
UTSW |
3 |
103,928,382 (GRCm39) |
intron |
probably benign |
|
|
R2519:Magi3
|
UTSW |
3 |
103,923,081 (GRCm39) |
missense |
probably benign |
0.00 |
|
R3104:Magi3
|
UTSW |
3 |
103,958,636 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R3105:Magi3
|
UTSW |
3 |
103,958,636 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R3619:Magi3
|
UTSW |
3 |
103,961,721 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4158:Magi3
|
UTSW |
3 |
103,958,277 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4160:Magi3
|
UTSW |
3 |
103,958,277 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4284:Magi3
|
UTSW |
3 |
103,923,184 (GRCm39) |
nonsense |
probably null |
|
|
R4285:Magi3
|
UTSW |
3 |
103,923,184 (GRCm39) |
nonsense |
probably null |
|
|
R4397:Magi3
|
UTSW |
3 |
104,127,030 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4512:Magi3
|
UTSW |
3 |
103,996,871 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R4676:Magi3
|
UTSW |
3 |
103,923,141 (GRCm39) |
missense |
probably benign |
|
|
R4758:Magi3
|
UTSW |
3 |
103,922,637 (GRCm39) |
missense |
probably benign |
0.01 |
|
R4940:Magi3
|
UTSW |
3 |
103,958,708 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5039:Magi3
|
UTSW |
3 |
104,013,107 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5160:Magi3
|
UTSW |
3 |
103,935,224 (GRCm39) |
missense |
possibly damaging |
0.46 |
|
R5422:Magi3
|
UTSW |
3 |
103,958,684 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5509:Magi3
|
UTSW |
3 |
103,922,818 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5839:Magi3
|
UTSW |
3 |
104,127,047 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5924:Magi3
|
UTSW |
3 |
103,961,854 (GRCm39) |
splice site |
probably null |
|
|
R6018:Magi3
|
UTSW |
3 |
104,013,128 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6189:Magi3
|
UTSW |
3 |
103,958,181 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6235:Magi3
|
UTSW |
3 |
103,923,384 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R6244:Magi3
|
UTSW |
3 |
103,923,013 (GRCm39) |
missense |
probably benign |
0.16 |
|
R6258:Magi3
|
UTSW |
3 |
103,996,912 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6358:Magi3
|
UTSW |
3 |
103,958,268 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6534:Magi3
|
UTSW |
3 |
103,992,536 (GRCm39) |
missense |
possibly damaging |
0.75 |
|
R6806:Magi3
|
UTSW |
3 |
103,954,285 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R6816:Magi3
|
UTSW |
3 |
103,997,227 (GRCm39) |
splice site |
probably null |
|
|
R6897:Magi3
|
UTSW |
3 |
103,996,873 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7011:Magi3
|
UTSW |
3 |
104,013,070 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7039:Magi3
|
UTSW |
3 |
103,958,699 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7196:Magi3
|
UTSW |
3 |
103,956,484 (GRCm39) |
missense |
probably benign |
0.01 |
|
R7237:Magi3
|
UTSW |
3 |
103,935,227 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7285:Magi3
|
UTSW |
3 |
103,941,430 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7709:Magi3
|
UTSW |
3 |
103,941,354 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7724:Magi3
|
UTSW |
3 |
103,923,243 (GRCm39) |
missense |
probably benign |
0.04 |
|
R7797:Magi3
|
UTSW |
3 |
103,958,618 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7950:Magi3
|
UTSW |
3 |
103,924,005 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8140:Magi3
|
UTSW |
3 |
103,941,402 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8204:Magi3
|
UTSW |
3 |
103,958,502 (GRCm39) |
missense |
probably benign |
|
|
R8229:Magi3
|
UTSW |
3 |
103,923,018 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8229:Magi3
|
UTSW |
3 |
103,923,017 (GRCm39) |
missense |
possibly damaging |
0.79 |
|
R8260:Magi3
|
UTSW |
3 |
103,922,625 (GRCm39) |
missense |
probably benign |
0.01 |
|
R8348:Magi3
|
UTSW |
3 |
103,958,531 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8368:Magi3
|
UTSW |
3 |
104,002,379 (GRCm39) |
critical splice donor site |
probably null |
|
|
R8543:Magi3
|
UTSW |
3 |
104,126,984 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R8762:Magi3
|
UTSW |
3 |
103,958,169 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8826:Magi3
|
UTSW |
3 |
103,992,662 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8847:Magi3
|
UTSW |
3 |
103,922,334 (GRCm39) |
missense |
probably benign |
0.09 |
|
R8892:Magi3
|
UTSW |
3 |
103,958,141 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8939:Magi3
|
UTSW |
3 |
103,996,748 (GRCm39) |
intron |
probably benign |
|
|
R9090:Magi3
|
UTSW |
3 |
103,923,264 (GRCm39) |
missense |
possibly damaging |
0.68 |
|
R9187:Magi3
|
UTSW |
3 |
103,923,073 (GRCm39) |
missense |
possibly damaging |
0.76 |
|
R9271:Magi3
|
UTSW |
3 |
103,923,264 (GRCm39) |
missense |
possibly damaging |
0.68 |
|
R9433:Magi3
|
UTSW |
3 |
103,922,473 (GRCm39) |
missense |
probably benign |
0.01 |
|
R9439:Magi3
|
UTSW |
3 |
103,922,473 (GRCm39) |
missense |
probably benign |
0.01 |
|
R9557:Magi3
|
UTSW |
3 |
103,924,933 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9557:Magi3
|
UTSW |
3 |
103,922,473 (GRCm39) |
missense |
probably benign |
0.01 |
|
R9697:Magi3
|
UTSW |
3 |
103,956,458 (GRCm39) |
critical splice donor site |
probably null |
|
|
R9796:Magi3
|
UTSW |
3 |
103,928,291 (GRCm39) |
missense |
probably benign |
|
|
X0026:Magi3
|
UTSW |
3 |
103,927,736 (GRCm39) |
missense |
probably benign |
0.00 |
|
| Predicted Primers |
PCR Primer
(F):5'- TGCTAGGATCATGTCAGGCTGAGG -3'
(R):5'- TCAGCAAAGCAGCTCAAGCAGG -3'
Sequencing Primer
(F):5'- CTCCTTCCTGAGCATGAGGAAAG -3'
(R):5'- AGCTCAAGCAGGAAGCTC -3'
|
| Posted On |
2013-06-12 |
Incidental Mutation