Incidental Mutation 'R5992:Magi2'
| ID |
480876 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Magi2
|
| Ensembl Gene |
ENSMUSG00000040003 |
| Gene Name |
membrane associated guanylate kinase, WW and PDZ domain containing 2 |
| Synonyms |
Magi-2, S-SCAM, Acvrinp1 |
| Accession Numbers |
|
| Essential gene? |
Essential
(E-score: 1.000)
|
| Stock # |
R5992 (G1)
|
| Quality Score |
225.009 |
|
Status
|
Not validated
|
| Chromosome |
5 |
| Chromosomal Location |
19227036-20704792 bp(+) (GRCm38) |
| Type of Mutation |
start codon destroyed |
| DNA Base Change (assembly) |
G to A
at 19227291 bp (GRCm38)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Methionine to Isoleucine
at position 1
(M1I)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000085872
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000088516]
[ENSMUST00000197354]
[ENSMUST00000197443]
|
| AlphaFold |
Q9WVQ1 |
| Predicted Effect |
probably null
Transcript: ENSMUST00000088516
AA Change: M1I
PolyPhen 2
Score 0.421 (Sensitivity: 0.89; Specificity: 0.90)
|
| SMART Domains |
Protein: ENSMUSP00000085872
Gene: ENSMUSG00000040003
AA Change: M1I
| Domain | Start | End | E-Value | Type |
|---|
|
PDZ
|
26 |
101 |
5.26e-9 |
SMART |
|
GuKc
|
107 |
290 |
2.76e-45 |
SMART |
|
WW
|
302 |
334 |
7.43e-12 |
SMART |
|
WW
|
348 |
380 |
2.4e-6 |
SMART |
|
PDZ
|
433 |
509 |
3.51e-19 |
SMART |
|
PDZ
|
612 |
682 |
2.3e-14 |
SMART |
|
PDZ
|
785 |
861 |
4.04e-19 |
SMART |
|
low complexity region
|
893 |
907 |
N/A |
INTRINSIC |
|
PDZ
|
928 |
1009 |
5.05e-20 |
SMART |
|
low complexity region
|
1052 |
1063 |
N/A |
INTRINSIC |
|
PDZ
|
1147 |
1221 |
3.88e-21 |
SMART |
|
low complexity region
|
1257 |
1270 |
N/A |
INTRINSIC |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000180594
|
| Predicted Effect |
probably null
Transcript: ENSMUST00000197354
AA Change: M1I
PolyPhen 2
Score 0.000 (Sensitivity: 1.00; Specificity: 0.00)
|
| SMART Domains |
Protein: ENSMUSP00000142576
Gene: ENSMUSG00000040003
AA Change: M1I
| Domain | Start | End | E-Value | Type |
|---|
|
PDZ
|
26 |
101 |
2.5e-11 |
SMART |
|
GuKc
|
107 |
290 |
1.4e-47 |
SMART |
|
WW
|
302 |
334 |
4.3e-14 |
SMART |
|
WW
|
348 |
380 |
1.4e-8 |
SMART |
|
PDZ
|
433 |
509 |
1.7e-21 |
SMART |
|
PDZ
|
612 |
682 |
1.1e-16 |
SMART |
|
PDZ
|
785 |
861 |
2e-21 |
SMART |
|
low complexity region
|
893 |
907 |
N/A |
INTRINSIC |
|
PDZ
|
928 |
1009 |
2.4e-22 |
SMART |
|
low complexity region
|
1052 |
1063 |
N/A |
INTRINSIC |
|
PDZ
|
1147 |
1221 |
1.9e-23 |
SMART |
|
low complexity region
|
1255 |
1269 |
N/A |
INTRINSIC |
|
low complexity region
|
1304 |
1319 |
N/A |
INTRINSIC |
|
low complexity region
|
1344 |
1363 |
N/A |
INTRINSIC |
|
low complexity region
|
1368 |
1384 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably null
Transcript: ENSMUST00000197443
AA Change: M1I
PolyPhen 2
Score 0.000 (Sensitivity: 1.00; Specificity: 0.00)
|
| SMART Domains |
Protein: ENSMUSP00000142764
Gene: ENSMUSG00000040003
AA Change: M1I
| Domain | Start | End | E-Value | Type |
|---|
|
PDZ
|
26 |
101 |
2.5e-11 |
SMART |
|
GuKc
|
107 |
290 |
1.4e-47 |
SMART |
|
WW
|
302 |
334 |
4.3e-14 |
SMART |
|
WW
|
348 |
380 |
1.4e-8 |
SMART |
|
PDZ
|
433 |
509 |
1.7e-21 |
SMART |
|
PDZ
|
612 |
682 |
1.1e-16 |
SMART |
|
PDZ
|
771 |
847 |
2e-21 |
SMART |
|
low complexity region
|
879 |
893 |
N/A |
INTRINSIC |
|
PDZ
|
914 |
995 |
2.4e-22 |
SMART |
|
low complexity region
|
1038 |
1049 |
N/A |
INTRINSIC |
|
PDZ
|
1133 |
1207 |
1.9e-23 |
SMART |
|
low complexity region
|
1241 |
1255 |
N/A |
INTRINSIC |
|
low complexity region
|
1290 |
1305 |
N/A |
INTRINSIC |
|
low complexity region
|
1330 |
1349 |
N/A |
INTRINSIC |
|
low complexity region
|
1354 |
1370 |
N/A |
INTRINSIC |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000197496
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000199384
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000200518
|
| Coding Region Coverage |
- 1x: 99.9%
- 3x: 99.5%
- 10x: 97.4%
- 20x: 91.9%
|
| Validation Efficiency |
|
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] The protein encoded by this gene interacts with atrophin-1. Atrophin-1 contains a polyglutamine repeat, expansion of which is responsible for dentatorubral and pallidoluysian atrophy. This encoded protein is characterized by two WW domains, a guanylate kinase-like domain, and multiple PDZ domains. It has structural similarity to the membrane-associated guanylate kinase homologue (MAGUK) family. [provided by RefSeq, Jul 2008]
PHENOTYPE: Homozygotes for a null allele show neonatal death and hippocampal neurons with altered dendritic spine morphology. Homozygotes for a different null allele die neonatally due to anuria and podocyte anomalies. Mice lacking all three isoforms develop proteinuria, podocytopathy and die of renal failure. [provided by MGI curators]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 73 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Aars2 |
T |
A |
17: 45,508,623 (GRCm38) |
L188* |
probably null |
Het |
| Acod1 |
C |
T |
14: 103,055,035 (GRCm38) |
R332C |
probably damaging |
Het |
| Adamts3 |
T |
A |
5: 89,691,335 (GRCm38) |
K852M |
probably damaging |
Het |
| Adm |
A |
T |
7: 110,627,696 (GRCm38) |
|
probably benign |
Het |
| Aff4 |
A |
G |
11: 53,373,010 (GRCm38) |
S286G |
probably damaging |
Het |
| Ank2 |
A |
G |
3: 126,959,651 (GRCm38) |
|
probably null |
Het |
| Aqr |
A |
T |
2: 114,143,049 (GRCm38) |
Y427* |
probably null |
Het |
| Arid1b |
C |
A |
17: 4,994,956 (GRCm38) |
|
probably benign |
Het |
| Arpp21 |
T |
A |
9: 112,143,485 (GRCm38) |
R259* |
probably null |
Het |
| Cep290 |
C |
T |
10: 100,543,321 (GRCm38) |
A55V |
possibly damaging |
Het |
| Chsy3 |
GT |
G |
18: 59,176,166 (GRCm38) |
163 |
probably null |
Het |
| Clcn2 |
T |
C |
16: 20,713,654 (GRCm38) |
E68G |
possibly damaging |
Het |
| Corin |
T |
A |
5: 72,316,389 (GRCm38) |
H699L |
probably benign |
Het |
| Cyld |
T |
C |
8: 88,733,053 (GRCm38) |
Y446H |
probably damaging |
Het |
| Dcst1 |
T |
A |
3: 89,352,576 (GRCm38) |
E613V |
probably damaging |
Het |
| Dlk1 |
T |
C |
12: 109,455,581 (GRCm38) |
C74R |
probably damaging |
Het |
| Dnah12 |
A |
C |
14: 26,697,341 (GRCm38) |
K128T |
probably benign |
Het |
| Dspp |
T |
A |
5: 104,178,451 (GRCm38) |
S893R |
unknown |
Het |
| Dtl |
A |
T |
1: 191,568,572 (GRCm38) |
|
probably null |
Het |
| F2rl1 |
T |
A |
13: 95,514,270 (GRCm38) |
S35C |
probably benign |
Het |
| Fcgbp |
A |
T |
7: 28,120,534 (GRCm38) |
Y2562F |
probably benign |
Het |
| Fgf10 |
A |
T |
13: 118,715,508 (GRCm38) |
D42V |
probably benign |
Het |
| Gm10271 |
A |
T |
10: 116,972,592 (GRCm38) |
F6L |
probably damaging |
Het |
| Gm21190 |
T |
A |
5: 15,524,851 (GRCm38) |
E256D |
probably damaging |
Het |
| Gm5157 |
A |
G |
7: 21,185,421 (GRCm38) |
S66P |
probably damaging |
Het |
| Gm884 |
A |
T |
11: 103,613,792 (GRCm38) |
M2450K |
possibly damaging |
Het |
| Hal |
T |
G |
10: 93,490,916 (GRCm38) |
L138R |
probably damaging |
Het |
| Hsd17b3 |
T |
C |
13: 64,059,470 (GRCm38) |
|
probably null |
Het |
| Lrsam1 |
T |
C |
2: 32,955,222 (GRCm38) |
T94A |
probably benign |
Het |
| Macc1 |
T |
C |
12: 119,447,585 (GRCm38) |
V696A |
probably damaging |
Het |
| March7 |
C |
A |
2: 60,245,220 (GRCm38) |
N674K |
probably benign |
Het |
| Mfap1b |
A |
G |
2: 121,470,295 (GRCm38) |
V34A |
probably benign |
Het |
| Mob3b |
G |
A |
4: 35,084,069 (GRCm38) |
S40L |
probably benign |
Het |
| Ndufs2 |
A |
T |
1: 171,236,418 (GRCm38) |
V386E |
probably damaging |
Het |
| Nfic |
C |
T |
10: 81,420,747 (GRCm38) |
A19T |
probably damaging |
Het |
| Nfs1 |
G |
A |
2: 156,134,453 (GRCm38) |
R174W |
probably damaging |
Het |
| Nin |
G |
T |
12: 70,045,524 (GRCm38) |
S670R |
possibly damaging |
Het |
| Nrxn1 |
T |
C |
17: 90,623,507 (GRCm38) |
I754V |
probably benign |
Het |
| Nwd1 |
T |
C |
8: 72,653,573 (GRCm38) |
|
probably null |
Het |
| Olfr1231 |
T |
A |
2: 89,303,359 (GRCm38) |
T78S |
possibly damaging |
Het |
| Olfr1238 |
T |
A |
2: 89,406,879 (GRCm38) |
M67L |
probably benign |
Het |
| Olfr575 |
G |
T |
7: 102,955,009 (GRCm38) |
N197K |
probably benign |
Het |
| Pcdhgb8 |
A |
G |
18: 37,763,449 (GRCm38) |
E524G |
probably damaging |
Het |
| Phlpp1 |
A |
T |
1: 106,318,993 (GRCm38) |
R638* |
probably null |
Het |
| Pkmyt1 |
G |
C |
17: 23,735,326 (GRCm38) |
W360S |
probably benign |
Het |
| Plxnd1 |
C |
A |
6: 115,967,787 (GRCm38) |
|
probably null |
Het |
| Poldip3 |
A |
T |
15: 83,129,229 (GRCm38) |
N322K |
probably damaging |
Het |
| Prmt3 |
A |
T |
7: 49,828,947 (GRCm38) |
I419L |
probably benign |
Het |
| Prss36 |
A |
T |
7: 127,944,830 (GRCm38) |
V123E |
probably damaging |
Het |
| Prss58 |
A |
G |
6: 40,897,769 (GRCm38) |
I46T |
probably damaging |
Het |
| Rac1 |
T |
C |
5: 143,506,998 (GRCm38) |
|
probably benign |
Het |
| Rb1cc1 |
A |
G |
1: 6,233,996 (GRCm38) |
Y36C |
probably damaging |
Het |
| Rif1 |
C |
G |
2: 52,095,844 (GRCm38) |
L614V |
probably damaging |
Het |
| Rnd2 |
C |
T |
11: 101,468,999 (GRCm38) |
L57F |
probably damaging |
Het |
| Rp1 |
A |
T |
1: 4,148,703 (GRCm38) |
F951L |
unknown |
Het |
| Rps6ka5 |
G |
T |
12: 100,575,250 (GRCm38) |
P417T |
possibly damaging |
Het |
| Ryr1 |
A |
G |
7: 29,067,637 (GRCm38) |
W2967R |
probably damaging |
Het |
| Sacs |
T |
A |
14: 61,205,543 (GRCm38) |
S1679R |
probably damaging |
Het |
| Scn1a |
A |
C |
2: 66,335,456 (GRCm38) |
W153G |
probably damaging |
Het |
| Serpinb7 |
A |
G |
1: 107,445,996 (GRCm38) |
Y114C |
probably damaging |
Het |
| Son |
T |
C |
16: 91,658,904 (GRCm38) |
M1513T |
probably benign |
Het |
| Spag8 |
C |
T |
4: 43,651,534 (GRCm38) |
V447M |
probably benign |
Het |
| St3gal2 |
T |
A |
8: 110,969,553 (GRCm38) |
Y257N |
probably damaging |
Het |
| Tars |
A |
T |
15: 11,397,196 (GRCm38) |
D40E |
probably damaging |
Het |
| Tlr3 |
T |
C |
8: 45,397,814 (GRCm38) |
H158R |
probably benign |
Het |
| Tppp2 |
G |
T |
14: 51,918,935 (GRCm38) |
V50L |
probably benign |
Het |
| Trrap |
T |
C |
5: 144,810,184 (GRCm38) |
S1503P |
probably benign |
Het |
| Ttll4 |
T |
G |
1: 74,685,391 (GRCm38) |
S573R |
probably damaging |
Het |
| Vmn2r104 |
A |
T |
17: 20,029,485 (GRCm38) |
N841K |
probably damaging |
Het |
| Vmn2r3 |
A |
T |
3: 64,259,647 (GRCm38) |
C688S |
probably damaging |
Het |
| Vps16 |
T |
C |
2: 130,424,449 (GRCm38) |
|
probably null |
Het |
| Zfp608 |
G |
A |
18: 54,899,248 (GRCm38) |
T540I |
probably benign |
Het |
| Zfp775 |
G |
A |
6: 48,619,816 (GRCm38) |
R208Q |
probably damaging |
Het |
|
| Other mutations in Magi2 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00908:Magi2
|
APN |
5 |
20,391,301 (GRCm38) |
missense |
probably benign |
0.05 |
|
IGL02120:Magi2
|
APN |
5 |
20,228,453 (GRCm38) |
critical splice donor site |
probably null |
|
|
IGL02341:Magi2
|
APN |
5 |
20,466,203 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL02411:Magi2
|
APN |
5 |
19,678,709 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL02657:Magi2
|
APN |
5 |
19,227,583 (GRCm38) |
missense |
probably damaging |
0.99 |
|
IGL02976:Magi2
|
APN |
5 |
20,534,475 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL03105:Magi2
|
APN |
5 |
20,543,618 (GRCm38) |
missense |
probably damaging |
0.97 |
|
IGL03246:Magi2
|
APN |
5 |
20,358,950 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL03329:Magi2
|
APN |
5 |
20,466,128 (GRCm38) |
missense |
possibly damaging |
0.95 |
|
LCD18:Magi2
|
UTSW |
5 |
19,954,511 (GRCm38) |
intron |
probably benign |
|
|
PIT4519001:Magi2
|
UTSW |
5 |
20,661,346 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R0009:Magi2
|
UTSW |
5 |
20,611,055 (GRCm38) |
missense |
probably benign |
0.15 |
|
R0009:Magi2
|
UTSW |
5 |
20,611,055 (GRCm38) |
missense |
probably benign |
0.15 |
|
R0352:Magi2
|
UTSW |
5 |
20,065,666 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R0362:Magi2
|
UTSW |
5 |
19,227,575 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R0496:Magi2
|
UTSW |
5 |
20,661,359 (GRCm38) |
splice site |
probably benign |
|
|
R1103:Magi2
|
UTSW |
5 |
20,611,103 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R1435:Magi2
|
UTSW |
5 |
20,358,945 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R1583:Magi2
|
UTSW |
5 |
19,227,332 (GRCm38) |
missense |
probably benign |
0.30 |
|
R1616:Magi2
|
UTSW |
5 |
20,609,326 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R1643:Magi2
|
UTSW |
5 |
20,705,506 (GRCm38) |
unclassified |
probably benign |
|
|
R1707:Magi2
|
UTSW |
5 |
20,215,493 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R1833:Magi2
|
UTSW |
5 |
19,227,457 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R1837:Magi2
|
UTSW |
5 |
20,465,827 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R1838:Magi2
|
UTSW |
5 |
20,465,827 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R1839:Magi2
|
UTSW |
5 |
20,465,827 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R1847:Magi2
|
UTSW |
5 |
20,602,460 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R2223:Magi2
|
UTSW |
5 |
20,465,672 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R2496:Magi2
|
UTSW |
5 |
19,678,752 (GRCm38) |
missense |
probably benign |
0.42 |
|
R2504:Magi2
|
UTSW |
5 |
20,358,936 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R2848:Magi2
|
UTSW |
5 |
20,602,461 (GRCm38) |
frame shift |
probably null |
|
|
R2879:Magi2
|
UTSW |
5 |
20,602,461 (GRCm38) |
frame shift |
probably null |
|
|
R2935:Magi2
|
UTSW |
5 |
20,602,461 (GRCm38) |
frame shift |
probably null |
|
|
R2936:Magi2
|
UTSW |
5 |
20,602,461 (GRCm38) |
frame shift |
probably null |
|
|
R3694:Magi2
|
UTSW |
5 |
20,602,461 (GRCm38) |
frame shift |
probably null |
|
|
R3783:Magi2
|
UTSW |
5 |
20,465,909 (GRCm38) |
missense |
probably damaging |
0.97 |
|
R3786:Magi2
|
UTSW |
5 |
20,465,909 (GRCm38) |
missense |
probably damaging |
0.97 |
|
R3787:Magi2
|
UTSW |
5 |
20,465,909 (GRCm38) |
missense |
probably damaging |
0.97 |
|
R3837:Magi2
|
UTSW |
5 |
20,215,468 (GRCm38) |
missense |
probably benign |
0.28 |
|
R4151:Magi2
|
UTSW |
5 |
19,227,292 (GRCm38) |
missense |
probably damaging |
0.97 |
|
R4721:Magi2
|
UTSW |
5 |
20,534,469 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R5005:Magi2
|
UTSW |
5 |
20,534,446 (GRCm38) |
missense |
probably damaging |
0.98 |
|
R5012:Magi2
|
UTSW |
5 |
20,465,620 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R5193:Magi2
|
UTSW |
5 |
20,358,972 (GRCm38) |
critical splice donor site |
probably null |
|
|
R5298:Magi2
|
UTSW |
5 |
20,569,162 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R5372:Magi2
|
UTSW |
5 |
20,702,110 (GRCm38) |
missense |
possibly damaging |
0.82 |
|
R5580:Magi2
|
UTSW |
5 |
20,215,424 (GRCm38) |
missense |
probably benign |
0.03 |
|
R5806:Magi2
|
UTSW |
5 |
20,651,204 (GRCm38) |
missense |
probably benign |
0.01 |
|
R5924:Magi2
|
UTSW |
5 |
20,611,069 (GRCm38) |
missense |
probably benign |
0.00 |
|
R6014:Magi2
|
UTSW |
5 |
20,611,093 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R6073:Magi2
|
UTSW |
5 |
20,569,288 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R6500:Magi2
|
UTSW |
5 |
20,602,347 (GRCm38) |
missense |
possibly damaging |
0.94 |
|
R6664:Magi2
|
UTSW |
5 |
20,702,397 (GRCm38) |
missense |
probably benign |
0.00 |
|
R7229:Magi2
|
UTSW |
5 |
20,465,588 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R7344:Magi2
|
UTSW |
5 |
20,550,240 (GRCm38) |
missense |
probably benign |
0.19 |
|
R7448:Magi2
|
UTSW |
5 |
20,358,956 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R7605:Magi2
|
UTSW |
5 |
20,228,385 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R7712:Magi2
|
UTSW |
5 |
20,550,282 (GRCm38) |
missense |
possibly damaging |
0.78 |
|
R7808:Magi2
|
UTSW |
5 |
20,465,840 (GRCm38) |
missense |
probably benign |
0.03 |
|
R7955:Magi2
|
UTSW |
5 |
20,389,072 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R8134:Magi2
|
UTSW |
5 |
20,391,394 (GRCm38) |
missense |
probably benign |
0.03 |
|
R8134:Magi2
|
UTSW |
5 |
20,391,367 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R8253:Magi2
|
UTSW |
5 |
20,609,307 (GRCm38) |
missense |
probably benign |
0.44 |
|
R8481:Magi2
|
UTSW |
5 |
20,389,154 (GRCm38) |
missense |
possibly damaging |
0.91 |
|
R8553:Magi2
|
UTSW |
5 |
20,651,200 (GRCm38) |
missense |
probably benign |
0.00 |
|
R8751:Magi2
|
UTSW |
5 |
20,534,464 (GRCm38) |
missense |
probably benign |
|
|
R8766:Magi2
|
UTSW |
5 |
20,195,125 (GRCm38) |
missense |
probably benign |
0.33 |
|
R8851:Magi2
|
UTSW |
5 |
20,065,620 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R8876:Magi2
|
UTSW |
5 |
20,651,192 (GRCm38) |
nonsense |
probably null |
|
|
R9120:Magi2
|
UTSW |
5 |
20,528,307 (GRCm38) |
missense |
possibly damaging |
0.81 |
|
R9335:Magi2
|
UTSW |
5 |
20,661,265 (GRCm38) |
missense |
|
|
|
R9367:Magi2
|
UTSW |
5 |
20,561,310 (GRCm38) |
missense |
probably damaging |
0.97 |
|
R9454:Magi2
|
UTSW |
5 |
20,466,178 (GRCm38) |
missense |
probably damaging |
0.97 |
|
R9474:Magi2
|
UTSW |
5 |
20,195,021 (GRCm38) |
missense |
probably benign |
0.00 |
|
R9577:Magi2
|
UTSW |
5 |
20,609,284 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R9673:Magi2
|
UTSW |
5 |
20,465,584 (GRCm38) |
missense |
possibly damaging |
0.86 |
|
R9696:Magi2
|
UTSW |
5 |
20,465,866 (GRCm38) |
missense |
probably benign |
0.35 |
|
X0065:Magi2
|
UTSW |
5 |
20,569,178 (GRCm38) |
missense |
possibly damaging |
0.94 |
|
Z1176:Magi2
|
UTSW |
5 |
20,702,109 (GRCm38) |
missense |
probably benign |
0.32 |
|
Z1177:Magi2
|
UTSW |
5 |
20,702,412 (GRCm38) |
missense |
probably benign |
|
|
| Predicted Primers |
PCR Primer
(F):5'- TGTCATTCAAGGGACAGCACAAC -3'
(R):5'- CGCTTTCATAGGCCACCTTG -3'
Sequencing Primer
(F):5'- CTACCTCTGCCCAGCCG -3'
(R):5'- ACCTTGCCCGGCTTCAC -3'
|
| Posted On |
2017-06-26 |
Incidental Mutation