Mutagenetix > Incidental Mutation

Incidental Mutation 'R5992:Sacs'

480912

Institutional Source

Beutler Lab

Gene Symbol

Sacs

Ensembl Gene

ENSMUSG00000048279

Gene Name

sacsin

Synonyms

E130115J16Rik

Accession Numbers

Genbank: NM_172809; MGI: 1354724; Ensembl: ENSMUST00000119943

Essential gene?

Non essential (E-score: 0.000) question?

Stock #

R5992 (G1)

Quality Score

225.009

Status

Not validated

Chromosome

Chromosomal Location

61138457-61240695 bp(+) (GRCm38)

Type of Mutation

missense

DNA Base Change (assembly)

T to A at 61205543 bp (GRCm38)

Zygosity

Heterozygous

Amino Acid Change

Serine to Arginine at position 1679 (S1679R)

Ref Sequence

ENSEMBL: ENSMUSP00000113377 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000089394] [ENSMUST00000119943] [ENSMUST00000229692]

AlphaFold

no structure available at present

Predicted Effect

probably benign
Transcript: ENSMUST00000089394

SMART Domains

Protein: ENSMUSP00000086816
Gene: ENSMUSG00000048279

Domain	Start	End	E-Value	Type
SCOP:d1lm8b_	8	66	3e-3	SMART
Blast:UBQ	9	81	3e-31	BLAST
Blast:HATPase_c	116	211	2e-10	BLAST
low complexity region	608	623	N/A	INTRINSIC
low complexity region	664	673	N/A	INTRINSIC

Predicted Effect

probably damaging
Transcript: ENSMUST00000119943
AA Change: S1679R

PolyPhen 2 Score 0.999 (Sensitivity: 0.14; Specificity: 0.99)

SMART Domains

Protein: ENSMUSP00000113377
Gene: ENSMUSG00000048279
AA Change: S1679R

Domain	Start	End	E-Value	Type
internal_repeat_1	61	514	1.35e-52	PROSPERO
low complexity region	608	623	N/A	INTRINSIC
low complexity region	664	673	N/A	INTRINSIC
low complexity region	1019	1033	N/A	INTRINSIC
low complexity region	1131	1145	N/A	INTRINSIC
low complexity region	1526	1537	N/A	INTRINSIC
low complexity region	2454	2463	N/A	INTRINSIC
internal_repeat_1	2475	2934	1.35e-52	PROSPERO
low complexity region	3751	3760	N/A	INTRINSIC
low complexity region	3997	4012	N/A	INTRINSIC
low complexity region	4285	4300	N/A	INTRINSIC
Blast:DnaJ	4304	4363	1e-31	BLAST
PDB:1IUR\|A	4309	4376	5e-39	PDB
SCOP:d1gh6a_	4317	4407	2e-3	SMART
HEPN	4454	4570	9.49e-24	SMART

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000150222

Predicted Effect

probably benign
Transcript: ENSMUST00000229692

Coding Region Coverage

1x: 99.9%
3x: 99.5%
10x: 97.4%
20x: 91.9%

Validation Efficiency

MGI Phenotype

PHENOTYPE: Mice homozygous for a knockout allele exhibit Purkinje cell degeneration with thickened tortuous dendrites and altered mitochondrial dysfunction. [provided by MGI curators]

Allele List at MGI

All alleles(3) : Gene trapped(3)

Other mutations in this stock

Total: 73 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
Aars2	T	A	17: 45,508,623 (GRCm38)	L188*	probably null	Het
Acod1	C	T	14: 103,055,035 (GRCm38)	R332C	probably damaging	Het
Adamts3	T	A	5: 89,691,335 (GRCm38)	K852M	probably damaging	Het
Adm	A	T	7: 110,627,696 (GRCm38)		probably benign	Het
Aff4	A	G	11: 53,373,010 (GRCm38)	S286G	probably damaging	Het
Ank2	A	G	3: 126,959,651 (GRCm38)		probably null	Het
Aqr	A	T	2: 114,143,049 (GRCm38)	Y427*	probably null	Het
Arid1b	C	A	17: 4,994,956 (GRCm38)		probably benign	Het
Arpp21	T	A	9: 112,143,485 (GRCm38)	R259*	probably null	Het
Cep290	C	T	10: 100,543,321 (GRCm38)	A55V	possibly damaging	Het
Chsy3	GT	G	18: 59,176,166 (GRCm38)	163	probably null	Het
Clcn2	T	C	16: 20,713,654 (GRCm38)	E68G	possibly damaging	Het
Corin	T	A	5: 72,316,389 (GRCm38)	H699L	probably benign	Het
Cyld	T	C	8: 88,733,053 (GRCm38)	Y446H	probably damaging	Het
Dcst1	T	A	3: 89,352,576 (GRCm38)	E613V	probably damaging	Het
Dlk1	T	C	12: 109,455,581 (GRCm38)	C74R	probably damaging	Het
Dnah12	A	C	14: 26,697,341 (GRCm38)	K128T	probably benign	Het
Dspp	T	A	5: 104,178,451 (GRCm38)	S893R	unknown	Het
Dtl	A	T	1: 191,568,572 (GRCm38)		probably null	Het
F2rl1	T	A	13: 95,514,270 (GRCm38)	S35C	probably benign	Het
Fcgbp	A	T	7: 28,120,534 (GRCm38)	Y2562F	probably benign	Het
Fgf10	A	T	13: 118,715,508 (GRCm38)	D42V	probably benign	Het
Gm10271	A	T	10: 116,972,592 (GRCm38)	F6L	probably damaging	Het
Gm21190	T	A	5: 15,524,851 (GRCm38)	E256D	probably damaging	Het
Gm5157	A	G	7: 21,185,421 (GRCm38)	S66P	probably damaging	Het
Gm884	A	T	11: 103,613,792 (GRCm38)	M2450K	possibly damaging	Het
Hal	T	G	10: 93,490,916 (GRCm38)	L138R	probably damaging	Het
Hsd17b3	T	C	13: 64,059,470 (GRCm38)		probably null	Het
Lrsam1	T	C	2: 32,955,222 (GRCm38)	T94A	probably benign	Het
Macc1	T	C	12: 119,447,585 (GRCm38)	V696A	probably damaging	Het
Magi2	G	A	5: 19,227,291 (GRCm38)	M1I	probably null	Het
March7	C	A	2: 60,245,220 (GRCm38)	N674K	probably benign	Het
Mfap1b	A	G	2: 121,470,295 (GRCm38)	V34A	probably benign	Het
Mob3b	G	A	4: 35,084,069 (GRCm38)	S40L	probably benign	Het
Ndufs2	A	T	1: 171,236,418 (GRCm38)	V386E	probably damaging	Het
Nfic	C	T	10: 81,420,747 (GRCm38)	A19T	probably damaging	Het
Nfs1	G	A	2: 156,134,453 (GRCm38)	R174W	probably damaging	Het
Nin	G	T	12: 70,045,524 (GRCm38)	S670R	possibly damaging	Het
Nrxn1	T	C	17: 90,623,507 (GRCm38)	I754V	probably benign	Het
Nwd1	T	C	8: 72,653,573 (GRCm38)		probably null	Het
Olfr1231	T	A	2: 89,303,359 (GRCm38)	T78S	possibly damaging	Het
Olfr1238	T	A	2: 89,406,879 (GRCm38)	M67L	probably benign	Het
Olfr575	G	T	7: 102,955,009 (GRCm38)	N197K	probably benign	Het
Pcdhgb8	A	G	18: 37,763,449 (GRCm38)	E524G	probably damaging	Het
Phlpp1	A	T	1: 106,318,993 (GRCm38)	R638*	probably null	Het
Pkmyt1	G	C	17: 23,735,326 (GRCm38)	W360S	probably benign	Het
Plxnd1	C	A	6: 115,967,787 (GRCm38)		probably null	Het
Poldip3	A	T	15: 83,129,229 (GRCm38)	N322K	probably damaging	Het
Prmt3	A	T	7: 49,828,947 (GRCm38)	I419L	probably benign	Het
Prss36	A	T	7: 127,944,830 (GRCm38)	V123E	probably damaging	Het
Prss58	A	G	6: 40,897,769 (GRCm38)	I46T	probably damaging	Het
Rac1	T	C	5: 143,506,998 (GRCm38)		probably benign	Het
Rb1cc1	A	G	1: 6,233,996 (GRCm38)	Y36C	probably damaging	Het
Rif1	C	G	2: 52,095,844 (GRCm38)	L614V	probably damaging	Het
Rnd2	C	T	11: 101,468,999 (GRCm38)	L57F	probably damaging	Het
Rp1	A	T	1: 4,148,703 (GRCm38)	F951L	unknown	Het
Rps6ka5	G	T	12: 100,575,250 (GRCm38)	P417T	possibly damaging	Het
Ryr1	A	G	7: 29,067,637 (GRCm38)	W2967R	probably damaging	Het
Scn1a	A	C	2: 66,335,456 (GRCm38)	W153G	probably damaging	Het
Serpinb7	A	G	1: 107,445,996 (GRCm38)	Y114C	probably damaging	Het
Son	T	C	16: 91,658,904 (GRCm38)	M1513T	probably benign	Het
Spag8	C	T	4: 43,651,534 (GRCm38)	V447M	probably benign	Het
St3gal2	T	A	8: 110,969,553 (GRCm38)	Y257N	probably damaging	Het
Tars	A	T	15: 11,397,196 (GRCm38)	D40E	probably damaging	Het
Tlr3	T	C	8: 45,397,814 (GRCm38)	H158R	probably benign	Het
Tppp2	G	T	14: 51,918,935 (GRCm38)	V50L	probably benign	Het
Trrap	T	C	5: 144,810,184 (GRCm38)	S1503P	probably benign	Het
Ttll4	T	G	1: 74,685,391 (GRCm38)	S573R	probably damaging	Het
Vmn2r104	A	T	17: 20,029,485 (GRCm38)	N841K	probably damaging	Het
Vmn2r3	A	T	3: 64,259,647 (GRCm38)	C688S	probably damaging	Het
Vps16	T	C	2: 130,424,449 (GRCm38)		probably null	Het
Zfp608	G	A	18: 54,899,248 (GRCm38)	T540I	probably benign	Het
Zfp775	G	A	6: 48,619,816 (GRCm38)	R208Q	probably damaging	Het

Other mutations in Sacs

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL01540:Sacs	APN	14	61,191,635 (GRCm38)	missense	possibly damaging	0.64
IGL01839:Sacs	APN	14	61,183,945 (GRCm38)	intron	probably benign
IGL02024:Sacs	APN	14	61,189,678 (GRCm38)	missense	probably damaging	0.96
IGL02247:Sacs	APN	14	61,192,535 (GRCm38)	missense	probably damaging	1.00
BB009:Sacs	UTSW	14	61,204,878 (GRCm38)	missense	probably damaging	0.99
BB019:Sacs	UTSW	14	61,204,878 (GRCm38)	missense	probably damaging	0.99
F6893:Sacs	UTSW	14	61,212,976 (GRCm38)	missense	probably benign
IGL03052:Sacs	UTSW	14	61,207,858 (GRCm38)	missense	probably damaging	0.99
R0090:Sacs	UTSW	14	61,205,440 (GRCm38)	missense	probably damaging	1.00
R0102:Sacs	UTSW	14	61,204,568 (GRCm38)	missense	probably damaging	1.00
R0102:Sacs	UTSW	14	61,204,568 (GRCm38)	missense	probably damaging	1.00
R0390:Sacs	UTSW	14	61,205,640 (GRCm38)	missense	possibly damaging	0.92
R0479:Sacs	UTSW	14	61,191,479 (GRCm38)	missense	probably damaging	0.99
R0556:Sacs	UTSW	14	61,183,958 (GRCm38)	missense	probably damaging	0.99
R0673:Sacs	UTSW	14	61,210,215 (GRCm38)	missense	possibly damaging	0.89
R0748:Sacs	UTSW	14	61,209,265 (GRCm38)	missense	probably damaging	0.99
R0931:Sacs	UTSW	14	61,203,495 (GRCm38)	missense	probably benign
R0972:Sacs	UTSW	14	61,211,963 (GRCm38)	nonsense	probably null
R1281:Sacs	UTSW	14	61,191,801 (GRCm38)	missense	probably benign	0.02
R1340:Sacs	UTSW	14	61,204,509 (GRCm38)	missense	probably damaging	0.98
R1351:Sacs	UTSW	14	61,202,761 (GRCm38)	missense	probably benign	0.00
R1499:Sacs	UTSW	14	61,213,704 (GRCm38)	missense	possibly damaging	0.70
R1538:Sacs	UTSW	14	61,210,059 (GRCm38)	missense	probably damaging	0.98
R1581:Sacs	UTSW	14	61,213,679 (GRCm38)	missense	probably damaging	0.96
R1599:Sacs	UTSW	14	61,203,638 (GRCm38)	missense	probably benign
R1631:Sacs	UTSW	14	61,210,732 (GRCm38)	nonsense	probably null
R1635:Sacs	UTSW	14	61,203,828 (GRCm38)	missense	probably damaging	0.98
R1655:Sacs	UTSW	14	61,191,782 (GRCm38)	missense	probably benign
R1660:Sacs	UTSW	14	61,209,009 (GRCm38)	missense	probably damaging	0.99
R1707:Sacs	UTSW	14	61,209,762 (GRCm38)	missense	probably benign	0.01
R1733:Sacs	UTSW	14	61,205,454 (GRCm38)	missense	probably damaging	1.00
R1772:Sacs	UTSW	14	61,210,897 (GRCm38)	missense	probably damaging	1.00
R1976:Sacs	UTSW	14	61,202,895 (GRCm38)	missense	probably benign
R2055:Sacs	UTSW	14	61,214,049 (GRCm38)	missense	probably damaging	0.97
R2083:Sacs	UTSW	14	61,206,506 (GRCm38)	missense	possibly damaging	0.69
R2091:Sacs	UTSW	14	61,191,919 (GRCm38)	missense	possibly damaging	0.95
R2105:Sacs	UTSW	14	61,173,441 (GRCm38)	missense	possibly damaging	0.90
R2109:Sacs	UTSW	14	61,173,453 (GRCm38)	splice site	probably null
R2117:Sacs	UTSW	14	61,213,771 (GRCm38)	missense	probably benign	0.01
R2122:Sacs	UTSW	14	61,212,316 (GRCm38)	missense	probably damaging	1.00
R2148:Sacs	UTSW	14	61,173,378 (GRCm38)	missense	probably damaging	0.97
R2151:Sacs	UTSW	14	61,209,640 (GRCm38)	missense	probably damaging	1.00
R2231:Sacs	UTSW	14	61,205,929 (GRCm38)	splice site	probably null
R2248:Sacs	UTSW	14	61,212,802 (GRCm38)	missense	probably damaging	1.00
R2271:Sacs	UTSW	14	61,204,660 (GRCm38)	missense	probably benign	0.06
R2314:Sacs	UTSW	14	61,207,759 (GRCm38)	missense	probably benign	0.17
R2436:Sacs	UTSW	14	61,202,905 (GRCm38)	missense	possibly damaging	0.94
R2445:Sacs	UTSW	14	61,205,206 (GRCm38)	missense	probably damaging	1.00
R2512:Sacs	UTSW	14	61,203,080 (GRCm38)	missense	probably benign	0.00
R3434:Sacs	UTSW	14	61,212,303 (GRCm38)	missense	probably damaging	1.00
R3785:Sacs	UTSW	14	61,183,961 (GRCm38)	missense	probably damaging	1.00
R3786:Sacs	UTSW	14	61,183,961 (GRCm38)	missense	probably damaging	1.00
R3796:Sacs	UTSW	14	61,206,121 (GRCm38)	missense	possibly damaging	0.87
R3798:Sacs	UTSW	14	61,206,121 (GRCm38)	missense	possibly damaging	0.87
R3872:Sacs	UTSW	14	61,148,068 (GRCm38)	missense	probably benign	0.30
R3873:Sacs	UTSW	14	61,192,286 (GRCm38)	missense	possibly damaging	0.64
R3892:Sacs	UTSW	14	61,204,387 (GRCm38)	missense	probably damaging	0.98
R4184:Sacs	UTSW	14	61,213,944 (GRCm38)	missense	probably damaging	0.97
R4204:Sacs	UTSW	14	61,173,443 (GRCm38)	missense	possibly damaging	0.93
R4249:Sacs	UTSW	14	61,203,457 (GRCm38)	missense	probably benign	0.02
R4256:Sacs	UTSW	14	61,206,337 (GRCm38)	missense	probably damaging	1.00
R4370:Sacs	UTSW	14	61,212,309 (GRCm38)	missense	probably damaging	1.00
R4445:Sacs	UTSW	14	61,204,686 (GRCm38)	missense	probably benign	0.30
R4503:Sacs	UTSW	14	61,207,603 (GRCm38)	missense	probably damaging	1.00
R4548:Sacs	UTSW	14	61,191,938 (GRCm38)	missense	probably damaging	1.00
R4582:Sacs	UTSW	14	61,191,698 (GRCm38)	missense	probably damaging	1.00
R4613:Sacs	UTSW	14	61,211,797 (GRCm38)	splice site	probably null
R4639:Sacs	UTSW	14	61,207,268 (GRCm38)	missense	probably benign	0.12
R4697:Sacs	UTSW	14	61,212,747 (GRCm38)	missense	probably benign	0.19
R4706:Sacs	UTSW	14	61,204,273 (GRCm38)	missense	probably damaging	1.00
R4717:Sacs	UTSW	14	61,212,855 (GRCm38)	missense	probably damaging	1.00
R4777:Sacs	UTSW	14	61,211,809 (GRCm38)	missense	probably damaging	1.00
R4888:Sacs	UTSW	14	61,212,198 (GRCm38)	missense	probably damaging	1.00
R4913:Sacs	UTSW	14	61,213,797 (GRCm38)	missense	probably benign	0.17
R4973:Sacs	UTSW	14	61,213,122 (GRCm38)	missense	probably damaging	1.00
R4986:Sacs	UTSW	14	61,213,043 (GRCm38)	nonsense	probably null
R5090:Sacs	UTSW	14	61,205,253 (GRCm38)	missense	probably damaging	1.00
R5243:Sacs	UTSW	14	61,205,957 (GRCm38)	nonsense	probably null
R5292:Sacs	UTSW	14	61,211,983 (GRCm38)	missense	probably damaging	1.00
R5308:Sacs	UTSW	14	61,192,400 (GRCm38)	missense	probably benign	0.21
R5337:Sacs	UTSW	14	61,193,514 (GRCm38)	intron	probably benign
R5502:Sacs	UTSW	14	61,206,100 (GRCm38)	missense	probably damaging	1.00
R5586:Sacs	UTSW	14	61,206,441 (GRCm38)	nonsense	probably null
R5692:Sacs	UTSW	14	61,207,839 (GRCm38)	missense	probably benign	0.00
R5725:Sacs	UTSW	14	61,211,110 (GRCm38)	missense	probably damaging	1.00
R5854:Sacs	UTSW	14	61,211,547 (GRCm38)	missense	probably damaging	1.00
R5959:Sacs	UTSW	14	61,212,400 (GRCm38)	missense	probably damaging	0.99
R5960:Sacs	UTSW	14	61,208,695 (GRCm38)	missense	probably benign	0.30
R5968:Sacs	UTSW	14	61,189,629 (GRCm38)	missense	probably damaging	0.99
R5983:Sacs	UTSW	14	61,205,199 (GRCm38)	missense	probably damaging	1.00
R6076:Sacs	UTSW	14	61,204,536 (GRCm38)	nonsense	probably null
R6175:Sacs	UTSW	14	61,212,826 (GRCm38)	missense	possibly damaging	0.82
R6347:Sacs	UTSW	14	61,211,160 (GRCm38)	missense	probably damaging	1.00
R6357:Sacs	UTSW	14	61,208,824 (GRCm38)	missense	possibly damaging	0.47
R6415:Sacs	UTSW	14	61,205,359 (GRCm38)	missense	probably damaging	1.00
R6469:Sacs	UTSW	14	61,191,248 (GRCm38)	missense	probably damaging	1.00
R6503:Sacs	UTSW	14	61,211,361 (GRCm38)	missense	probably benign	0.00
R6523:Sacs	UTSW	14	61,202,961 (GRCm38)	missense	probably damaging	0.99
R6615:Sacs	UTSW	14	61,208,934 (GRCm38)	missense	probably benign	0.15
R6729:Sacs	UTSW	14	61,210,518 (GRCm38)	missense	probably damaging	1.00
R6731:Sacs	UTSW	14	61,180,700 (GRCm38)	splice site	probably null
R6797:Sacs	UTSW	14	61,213,073 (GRCm38)	missense	probably damaging	1.00
R6852:Sacs	UTSW	14	61,179,288 (GRCm38)	missense	possibly damaging	0.87
R6922:Sacs	UTSW	14	61,211,425 (GRCm38)	missense	probably damaging	1.00
R7023:Sacs	UTSW	14	61,208,815 (GRCm38)	missense	probably benign	0.04
R7047:Sacs	UTSW	14	61,213,002 (GRCm38)	missense	probably damaging	1.00
R7051:Sacs	UTSW	14	61,208,928 (GRCm38)	missense	probably benign	0.25
R7069:Sacs	UTSW	14	61,212,496 (GRCm38)	missense	probably damaging	1.00
R7082:Sacs	UTSW	14	61,210,517 (GRCm38)	missense	possibly damaging	0.94
R7108:Sacs	UTSW	14	61,211,009 (GRCm38)	nonsense	probably null
R7122:Sacs	UTSW	14	61,210,396 (GRCm38)	missense	probably damaging	1.00
R7194:Sacs	UTSW	14	61,210,089 (GRCm38)	missense	possibly damaging	0.95
R7214:Sacs	UTSW	14	61,191,792 (GRCm38)	missense	probably benign
R7221:Sacs	UTSW	14	61,208,806 (GRCm38)	missense	probably damaging	0.99
R7274:Sacs	UTSW	14	61,214,081 (GRCm38)	missense	possibly damaging	0.88
R7344:Sacs	UTSW	14	61,207,444 (GRCm38)	missense	possibly damaging	0.81
R7440:Sacs	UTSW	14	61,191,605 (GRCm38)	missense	probably benign	0.10
R7474:Sacs	UTSW	14	61,211,178 (GRCm38)	missense	probably benign	0.04
R7512:Sacs	UTSW	14	61,204,430 (GRCm38)	missense	probably benign	0.04
R7641:Sacs	UTSW	14	61,202,871 (GRCm38)	missense	probably damaging	0.97
R7649:Sacs	UTSW	14	61,203,228 (GRCm38)	missense	possibly damaging	0.53
R7703:Sacs	UTSW	14	61,206,090 (GRCm38)	missense	possibly damaging	0.81
R7792:Sacs	UTSW	14	61,209,773 (GRCm38)	missense	probably benign	0.00
R7805:Sacs	UTSW	14	61,203,591 (GRCm38)	missense	not run
R7822:Sacs	UTSW	14	61,192,203 (GRCm38)	missense	probably benign	0.03
R7882:Sacs	UTSW	14	61,207,071 (GRCm38)	missense	probably benign	0.02
R7932:Sacs	UTSW	14	61,204,878 (GRCm38)	missense	probably damaging	0.99
R8031:Sacs	UTSW	14	61,204,191 (GRCm38)	missense	probably damaging	0.96
R8064:Sacs	UTSW	14	61,192,175 (GRCm38)	missense	possibly damaging	0.92
R8083:Sacs	UTSW	14	61,210,717 (GRCm38)	missense	possibly damaging	0.77
R8204:Sacs	UTSW	14	61,212,948 (GRCm38)	missense	probably damaging	0.96
R8293:Sacs	UTSW	14	61,191,099 (GRCm38)	missense	probably damaging	0.99
R8316:Sacs	UTSW	14	61,189,619 (GRCm38)	missense	possibly damaging	0.84
R8393:Sacs	UTSW	14	61,173,206 (GRCm38)	start codon destroyed	probably null	0.06
R8434:Sacs	UTSW	14	61,213,187 (GRCm38)	nonsense	probably null
R8482:Sacs	UTSW	14	61,202,955 (GRCm38)	missense	probably benign
R8497:Sacs	UTSW	14	61,192,253 (GRCm38)	missense	probably benign	0.00
R8557:Sacs	UTSW	14	61,207,276 (GRCm38)	missense	probably damaging	1.00
R8698:Sacs	UTSW	14	61,213,353 (GRCm38)	missense	probably benign
R8840:Sacs	UTSW	14	61,191,728 (GRCm38)	missense	probably benign	0.25
R8924:Sacs	UTSW	14	61,211,253 (GRCm38)	missense	probably damaging	1.00
R8924:Sacs	UTSW	14	61,192,446 (GRCm38)	missense	probably benign	0.22
R8941:Sacs	UTSW	14	61,192,573 (GRCm38)	missense	probably benign	0.00
R9007:Sacs	UTSW	14	61,207,736 (GRCm38)	missense	probably benign	0.04
R9008:Sacs	UTSW	14	61,204,543 (GRCm38)	missense	probably benign	0.19
R9070:Sacs	UTSW	14	61,210,302 (GRCm38)	missense	probably benign
R9147:Sacs	UTSW	14	61,212,688 (GRCm38)	missense	possibly damaging	0.86
R9185:Sacs	UTSW	14	61,206,666 (GRCm38)	missense	probably damaging	0.98
R9290:Sacs	UTSW	14	61,184,050 (GRCm38)	missense	probably benign	0.17
R9294:Sacs	UTSW	14	61,240,319 (GRCm38)	missense	possibly damaging	0.84
R9339:Sacs	UTSW	14	61,205,860 (GRCm38)	missense	probably benign	0.00
R9341:Sacs	UTSW	14	61,208,770 (GRCm38)	missense	probably benign	0.08
R9343:Sacs	UTSW	14	61,208,770 (GRCm38)	missense	probably benign	0.08
R9370:Sacs	UTSW	14	61,203,631 (GRCm38)	missense	probably damaging	1.00
R9433:Sacs	UTSW	14	61,206,548 (GRCm38)	missense	probably damaging	1.00
R9460:Sacs	UTSW	14	61,204,162 (GRCm38)	missense	probably benign	0.34
R9548:Sacs	UTSW	14	61,203,243 (GRCm38)	missense	probably benign	0.02
R9564:Sacs	UTSW	14	61,211,597 (GRCm38)	missense	probably damaging	1.00
R9644:Sacs	UTSW	14	61,205,979 (GRCm38)	missense	probably benign	0.00
R9683:Sacs	UTSW	14	61,213,432 (GRCm38)	missense	possibly damaging	0.95
R9706:Sacs	UTSW	14	61,208,373 (GRCm38)	nonsense	probably null
X0067:Sacs	UTSW	14	61,208,019 (GRCm38)	missense	probably damaging	1.00
Z1176:Sacs	UTSW	14	61,213,200 (GRCm38)	missense	probably damaging	1.00
Z1176:Sacs	UTSW	14	61,210,830 (GRCm38)	nonsense	probably null
Z1177:Sacs	UTSW	14	61,207,981 (GRCm38)	missense	possibly damaging	0.93
Z1177:Sacs	UTSW	14	61,191,551 (GRCm38)	missense	possibly damaging	0.48

Predicted Primers

PCR Primer
(F):5'- AGGAAGTTCCCCAACCAGTTC -3'
(R):5'- TGCTGCTACAAGTCTTCATGAG -3'

Sequencing Primer
(F):5'- CCCAACCAGTTCAAACCATTTATAG -3'
(R):5'- CAAGTCTTCATGAGTTTAGCAGC -3'

Posted On

2017-06-26