Incidental Mutation 'R5979:Muc2'
| ID |
481313 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Muc2
|
| Ensembl Gene |
ENSMUSG00000025515 |
| Gene Name |
mucin 2 |
| Synonyms |
2010015E03Rik |
| MMRRC Submission |
044161-MU
|
| Accession Numbers |
|
| Essential gene? |
Probably non essential
(E-score: 0.099)
|
| Stock # |
R5979 (G1)
|
| Quality Score |
225.009 |
|
Status
|
Validated
|
| Chromosome |
7 |
| Chromosomal Location |
141276583-141308428 bp(+) (GRCm39) |
| Type of Mutation |
splice site (3 bp from exon) |
| DNA Base Change (assembly) |
A to G
at 141283493 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000136692
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000167366]
[ENSMUST00000179227]
[ENSMUST00000185406]
[ENSMUST00000185823]
|
| AlphaFold |
no structure available at present |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000167366
|
| SMART Domains |
Protein: ENSMUSP00000128250
Gene: ENSMUSG00000025515
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:VWD
|
3 |
72 |
2.3e-14 |
PFAM |
|
C8
|
107 |
181 |
1.82e-31 |
SMART |
|
| Predicted Effect |
probably null
Transcript: ENSMUST00000179227
|
| SMART Domains |
Protein: ENSMUSP00000136692
Gene: ENSMUSG00000025515
| Domain | Start | End | E-Value | Type |
|---|
|
C8
|
11 |
85 |
1.61e-32 |
SMART |
|
Blast:VWD
|
102 |
128 |
5e-8 |
BLAST |
|
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000185406
AA Change: T702A
PolyPhen 2
Score 0.456 (Sensitivity: 0.89; Specificity: 0.90)
|
| SMART Domains |
Protein: ENSMUSP00000141040
Gene: ENSMUSG00000025515
AA Change: T702A
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
5 |
18 |
N/A |
INTRINSIC |
|
VWD
|
20 |
183 |
1.5e-40 |
SMART |
|
C8
|
216 |
290 |
3.9e-15 |
SMART |
|
Pfam:TIL
|
293 |
349 |
5.4e-10 |
PFAM |
|
VWC
|
351 |
411 |
7e-4 |
SMART |
|
VWD
|
378 |
542 |
8.8e-44 |
SMART |
|
C8
|
579 |
653 |
1.2e-36 |
SMART |
|
SCOP:d1coua_
|
654 |
728 |
4e-8 |
SMART |
|
VWC_def
|
820 |
865 |
1.3e-2 |
SMART |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000185823
|
| SMART Domains |
Protein: ENSMUSP00000140855
Gene: ENSMUSG00000025515
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:VWD
|
3 |
73 |
5.6e-14 |
PFAM |
|
C8
|
108 |
182 |
1.4e-35 |
SMART |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000187789
|
| Coding Region Coverage |
- 1x: 99.9%
- 3x: 99.6%
- 10x: 98.4%
- 20x: 95.4%
|
| Validation Efficiency |
100% (87/87) |
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene encodes a member of the mucin protein family. Mucins are high molecular weight glycoproteins produced by many epithelial tissues. The protein encoded by this gene is secreted and forms an insoluble mucous barrier that protects the gut lumen. The protein polymerizes into a gel of which 80% is composed of oligosaccharide side chains by weight. The protein features a central domain containing tandem repeats rich in threonine and proline that varies between 50 and 115 copies in different individuals. Downregulation of this gene has been observed in patients with Crohn disease and ulcerative colitis. [provided by RefSeq, Oct 2016]
PHENOTYPE: Homozygotes for a point mutation have soft feces at weaning and develop diarrhea associated with malapsorption syndrome. Homozygous null mutants pass blood in their feces at 6 months, and 65% of null mutants have intestinal tumors at 1 year. [provided by MGI curators]
|
| Allele List at MGI |
All alleles(7) : Targeted(3) Chemically induced(4)
|
| Other mutations in this stock |
Total: 84 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Acss2 |
A |
G |
2: 155,364,029 (GRCm39) |
I103V |
possibly damaging |
Het |
| Adam3 |
T |
C |
8: 25,167,383 (GRCm39) |
N36S |
probably benign |
Het |
| Adamts3 |
A |
G |
5: 90,009,528 (GRCm39) |
V45A |
probably damaging |
Het |
| Afg3l2 |
G |
T |
18: 67,554,329 (GRCm39) |
L458M |
probably damaging |
Het |
| Agtpbp1 |
A |
T |
13: 59,681,860 (GRCm39) |
L69* |
probably null |
Het |
| Alkbh5 |
T |
A |
11: 60,429,517 (GRCm39) |
I90N |
probably damaging |
Het |
| Alx1 |
T |
C |
10: 102,858,120 (GRCm39) |
Y193C |
probably damaging |
Het |
| Ankrd11 |
T |
G |
8: 123,619,139 (GRCm39) |
D1571A |
probably damaging |
Het |
| Brd4 |
T |
C |
17: 32,417,700 (GRCm39) |
D124G |
probably benign |
Het |
| C2cd2 |
G |
A |
16: 97,676,418 (GRCm39) |
T443I |
probably benign |
Het |
| Casp8 |
A |
T |
1: 58,868,071 (GRCm39) |
M171L |
probably benign |
Het |
| Cd200r4 |
G |
A |
16: 44,653,295 (GRCm39) |
V22I |
probably benign |
Het |
| Cdcp2 |
A |
G |
4: 106,962,478 (GRCm39) |
Y217C |
probably damaging |
Het |
| Cfh |
C |
A |
1: 140,046,409 (GRCm39) |
V556F |
possibly damaging |
Het |
| Chka |
T |
G |
19: 3,934,513 (GRCm39) |
I182M |
probably damaging |
Het |
| Cope |
T |
C |
8: 70,755,193 (GRCm39) |
|
probably null |
Het |
| Coq10b |
T |
C |
1: 55,092,077 (GRCm39) |
V15A |
probably benign |
Het |
| Cpne9 |
T |
A |
6: 113,270,710 (GRCm39) |
S309T |
probably benign |
Het |
| Daam2 |
T |
A |
17: 49,766,232 (GRCm39) |
H992L |
possibly damaging |
Het |
| Dctn3 |
T |
C |
4: 41,715,393 (GRCm39) |
|
probably null |
Het |
| Dhx35 |
G |
T |
2: 158,684,789 (GRCm39) |
R536L |
probably benign |
Het |
| Dnah8 |
G |
T |
17: 31,034,638 (GRCm39) |
E4186* |
probably null |
Het |
| Dnah9 |
A |
G |
11: 65,725,307 (GRCm39) |
L4282P |
probably damaging |
Het |
| Dpp10 |
A |
G |
1: 123,312,012 (GRCm39) |
|
probably null |
Het |
| Dst |
T |
A |
1: 34,199,453 (GRCm39) |
|
probably benign |
Het |
| Ehbp1 |
C |
A |
11: 22,101,887 (GRCm39) |
V214L |
probably benign |
Het |
| Fam131b |
T |
C |
6: 42,298,905 (GRCm39) |
D25G |
probably damaging |
Het |
| Fbxl13 |
T |
A |
5: 21,787,089 (GRCm39) |
I283F |
probably damaging |
Het |
| Gabrr3 |
T |
G |
16: 59,254,931 (GRCm39) |
N205K |
possibly damaging |
Het |
| Got1l1 |
C |
T |
8: 27,687,951 (GRCm39) |
|
probably null |
Het |
| Gprin1 |
G |
A |
13: 54,887,791 (GRCm39) |
A161V |
probably benign |
Het |
| Hepacam2 |
A |
T |
6: 3,476,149 (GRCm39) |
F183I |
probably damaging |
Het |
| Hmx2 |
A |
G |
7: 131,156,279 (GRCm39) |
T82A |
probably benign |
Het |
| Igsf10 |
C |
T |
3: 59,243,894 (GRCm39) |
E147K |
probably damaging |
Het |
| Kndc1 |
G |
A |
7: 139,519,740 (GRCm39) |
A1700T |
probably benign |
Het |
| Knl1 |
T |
C |
2: 118,899,841 (GRCm39) |
V514A |
possibly damaging |
Het |
| Lama2 |
T |
C |
10: 27,111,728 (GRCm39) |
D764G |
probably damaging |
Het |
| Lgi3 |
G |
A |
14: 70,773,900 (GRCm39) |
R358H |
probably damaging |
Het |
| Limd1 |
G |
T |
9: 123,308,479 (GRCm39) |
Q59H |
possibly damaging |
Het |
| Lrrk2 |
A |
G |
15: 91,657,148 (GRCm39) |
Y1814C |
possibly damaging |
Het |
| Lysmd3 |
G |
A |
13: 81,813,393 (GRCm39) |
|
probably null |
Het |
| Mroh7 |
T |
C |
4: 106,578,123 (GRCm39) |
N185S |
probably benign |
Het |
| Nlrp3 |
T |
C |
11: 59,439,797 (GRCm39) |
F458S |
probably benign |
Het |
| Nop58 |
A |
T |
1: 59,741,990 (GRCm39) |
D173V |
probably damaging |
Het |
| Nrxn1 |
C |
T |
17: 91,395,631 (GRCm39) |
R175H |
possibly damaging |
Het |
| Nxpe4 |
A |
G |
9: 48,307,862 (GRCm39) |
N322S |
probably benign |
Het |
| Ocstamp |
A |
G |
2: 165,239,467 (GRCm39) |
S240P |
probably damaging |
Het |
| Or10a5 |
G |
A |
7: 106,635,543 (GRCm39) |
M60I |
probably damaging |
Het |
| Or2j3 |
T |
C |
17: 38,616,083 (GRCm39) |
K90E |
probably benign |
Het |
| Or8b36 |
ATTGCTGTTT |
ATTGCTGTTTGCTGTTT |
9: 37,937,836 (GRCm39) |
|
probably null |
Het |
| Or9e1 |
A |
G |
11: 58,732,666 (GRCm39) |
H242R |
probably damaging |
Het |
| Ovch2 |
G |
A |
7: 107,393,595 (GRCm39) |
T177I |
possibly damaging |
Het |
| Parn |
A |
C |
16: 13,424,035 (GRCm39) |
L454R |
probably damaging |
Het |
| Pcdhb12 |
T |
A |
18: 37,571,044 (GRCm39) |
L730Q |
possibly damaging |
Het |
| Phf3 |
G |
T |
1: 30,844,827 (GRCm39) |
F1377L |
probably damaging |
Het |
| Pign |
G |
T |
1: 105,516,999 (GRCm39) |
S542R |
probably benign |
Het |
| Prex2 |
G |
T |
1: 11,202,596 (GRCm39) |
V502F |
probably damaging |
Het |
| Psmd1 |
A |
T |
1: 86,017,775 (GRCm39) |
I529F |
possibly damaging |
Het |
| Ptafr |
A |
G |
4: 132,306,616 (GRCm39) |
E2G |
probably benign |
Het |
| R3hdm1 |
A |
G |
1: 128,138,960 (GRCm39) |
N380S |
probably benign |
Het |
| Rbm12 |
A |
C |
2: 155,939,679 (GRCm39) |
|
probably benign |
Het |
| Rgl1 |
A |
G |
1: 152,433,244 (GRCm39) |
Y174H |
probably damaging |
Het |
| Rps6kc1 |
A |
G |
1: 190,532,632 (GRCm39) |
S457P |
probably damaging |
Het |
| Sall4 |
A |
T |
2: 168,592,263 (GRCm39) |
S964T |
probably benign |
Het |
| Sart1 |
T |
A |
19: 5,431,251 (GRCm39) |
I681F |
probably damaging |
Het |
| Serinc5 |
T |
C |
13: 92,797,644 (GRCm39) |
L49P |
probably benign |
Het |
| Serpinb9e |
T |
C |
13: 33,439,036 (GRCm39) |
V154A |
probably benign |
Het |
| Skic2 |
A |
T |
17: 35,060,439 (GRCm39) |
N851K |
probably benign |
Het |
| Smox |
G |
A |
2: 131,358,334 (GRCm39) |
V136I |
probably damaging |
Het |
| Sspo |
C |
T |
6: 48,440,627 (GRCm39) |
T1747I |
probably benign |
Het |
| Swt1 |
A |
T |
1: 151,283,339 (GRCm39) |
D339E |
possibly damaging |
Het |
| Synpo2 |
A |
G |
3: 122,911,060 (GRCm39) |
L195P |
probably damaging |
Het |
| Syt7 |
G |
T |
19: 10,420,843 (GRCm39) |
G414W |
probably damaging |
Het |
| Tmem186 |
G |
A |
16: 8,454,024 (GRCm39) |
T79I |
probably damaging |
Het |
| Tmem39a |
A |
T |
16: 38,396,106 (GRCm39) |
N113I |
probably damaging |
Het |
| Trim14 |
C |
T |
4: 46,507,239 (GRCm39) |
V326M |
probably damaging |
Het |
| Trim58 |
A |
G |
11: 58,536,909 (GRCm39) |
E234G |
probably damaging |
Het |
| Ttr |
T |
C |
18: 20,803,059 (GRCm39) |
L75P |
probably damaging |
Het |
| Ubr1 |
C |
T |
2: 120,776,863 (GRCm39) |
V293I |
probably benign |
Het |
| Vmn1r91 |
T |
A |
7: 19,835,990 (GRCm39) |
V303E |
probably benign |
Het |
| Vmn2r30 |
A |
C |
7: 7,315,334 (GRCm39) |
I833S |
probably damaging |
Het |
| Zfp131 |
G |
T |
13: 120,237,982 (GRCm39) |
N125K |
probably benign |
Het |
| Zfp169 |
A |
T |
13: 48,644,516 (GRCm39) |
|
probably benign |
Het |
| Zfp213 |
C |
A |
17: 23,776,885 (GRCm39) |
E386* |
probably null |
Het |
|
| Other mutations in Muc2 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
Eeyore
|
APN |
7 |
141,693,356 (GRCm38) |
missense |
probably benign |
0.35 |
|
kenny
|
APN |
7 |
0 () |
nonsense |
|
|
|
Winnie
|
APN |
7 |
141,286,029 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01303:Muc2
|
APN |
7 |
141,306,132 (GRCm39) |
missense |
probably benign |
|
|
IGL01482:Muc2
|
APN |
7 |
141,307,797 (GRCm39) |
missense |
probably damaging |
0.96 |
|
IGL01875:Muc2
|
APN |
7 |
141,306,477 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL02088:Muc2
|
APN |
7 |
141,305,241 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02415:Muc2
|
APN |
7 |
141,305,609 (GRCm39) |
nonsense |
probably null |
|
|
IGL02548:Muc2
|
APN |
7 |
141,305,594 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02836:Muc2
|
APN |
7 |
141,300,450 (GRCm39) |
unclassified |
probably benign |
|
|
IGL03196:Muc2
|
APN |
7 |
141,301,367 (GRCm39) |
missense |
probably damaging |
0.97 |
|
Muskatenwein
|
UTSW |
7 |
141,307,176 (GRCm39) |
missense |
unknown |
|
|
nomoco
|
UTSW |
7 |
141,307,456 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Schlendrian
|
UTSW |
7 |
141,281,925 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Seco
|
UTSW |
7 |
141,284,976 (GRCm39) |
missense |
probably damaging |
1.00 |
|
BB001:Muc2
|
UTSW |
7 |
141,281,631 (GRCm39) |
missense |
probably damaging |
1.00 |
|
BB011:Muc2
|
UTSW |
7 |
141,281,631 (GRCm39) |
missense |
probably damaging |
1.00 |
|
E0370:Muc2
|
UTSW |
7 |
141,282,598 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0127:Muc2
|
UTSW |
7 |
141,302,691 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0179:Muc2
|
UTSW |
7 |
141,302,708 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0201:Muc2
|
UTSW |
7 |
141,699,185 (GRCm38) |
frame shift |
probably null |
|
|
R0299:Muc2
|
UTSW |
7 |
141,306,466 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0547:Muc2
|
UTSW |
7 |
141,699,185 (GRCm38) |
frame shift |
probably null |
|
|
R0699:Muc2
|
UTSW |
7 |
141,306,037 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0900:Muc2
|
UTSW |
7 |
141,699,185 (GRCm38) |
frame shift |
probably null |
|
|
R1348:Muc2
|
UTSW |
7 |
141,699,185 (GRCm38) |
frame shift |
probably null |
|
|
R1466:Muc2
|
UTSW |
7 |
141,302,711 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1466:Muc2
|
UTSW |
7 |
141,302,711 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1625:Muc2
|
UTSW |
7 |
141,283,405 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2010:Muc2
|
UTSW |
7 |
141,287,444 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R2149:Muc2
|
UTSW |
7 |
141,699,185 (GRCm38) |
frame shift |
probably null |
|
|
R2163:Muc2
|
UTSW |
7 |
141,699,185 (GRCm38) |
frame shift |
probably null |
|
|
R3008:Muc2
|
UTSW |
7 |
141,281,347 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R3110:Muc2
|
UTSW |
7 |
141,299,225 (GRCm39) |
unclassified |
probably benign |
|
|
R3112:Muc2
|
UTSW |
7 |
141,299,225 (GRCm39) |
unclassified |
probably benign |
|
|
R3424:Muc2
|
UTSW |
7 |
141,279,595 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R3786:Muc2
|
UTSW |
7 |
141,283,590 (GRCm39) |
missense |
probably benign |
0.01 |
|
R3854:Muc2
|
UTSW |
7 |
141,308,081 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3964:Muc2
|
UTSW |
7 |
141,286,233 (GRCm39) |
missense |
probably benign |
0.17 |
|
R3965:Muc2
|
UTSW |
7 |
141,286,233 (GRCm39) |
missense |
probably benign |
0.17 |
|
R3966:Muc2
|
UTSW |
7 |
141,286,233 (GRCm39) |
missense |
probably benign |
0.17 |
|
R3973:Muc2
|
UTSW |
7 |
141,300,541 (GRCm39) |
unclassified |
probably benign |
|
|
R3974:Muc2
|
UTSW |
7 |
141,300,541 (GRCm39) |
unclassified |
probably benign |
|
|
R3976:Muc2
|
UTSW |
7 |
141,300,541 (GRCm39) |
unclassified |
probably benign |
|
|
R4327:Muc2
|
UTSW |
7 |
141,281,577 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R4694:Muc2
|
UTSW |
7 |
141,306,082 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4764:Muc2
|
UTSW |
7 |
141,299,345 (GRCm39) |
missense |
possibly damaging |
0.88 |
|
R4769:Muc2
|
UTSW |
7 |
141,286,260 (GRCm39) |
critical splice donor site |
probably null |
|
|
R4798:Muc2
|
UTSW |
7 |
141,307,877 (GRCm39) |
missense |
probably benign |
0.01 |
|
R4900:Muc2
|
UTSW |
7 |
141,303,280 (GRCm39) |
missense |
probably benign |
0.32 |
|
R5383:Muc2
|
UTSW |
7 |
141,307,456 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5489:Muc2
|
UTSW |
7 |
141,305,169 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5615:Muc2
|
UTSW |
7 |
141,277,446 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5856:Muc2
|
UTSW |
7 |
141,299,381 (GRCm39) |
unclassified |
probably benign |
|
|
R5919:Muc2
|
UTSW |
7 |
141,281,171 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R5953:Muc2
|
UTSW |
7 |
141,287,951 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R5979:Muc2
|
UTSW |
7 |
141,305,143 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R6175:Muc2
|
UTSW |
7 |
141,282,875 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6213:Muc2
|
UTSW |
7 |
141,305,151 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6281:Muc2
|
UTSW |
7 |
141,306,140 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6321:Muc2
|
UTSW |
7 |
141,287,397 (GRCm39) |
missense |
probably benign |
0.28 |
|
R6390:Muc2
|
UTSW |
7 |
141,305,883 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R6485:Muc2
|
UTSW |
7 |
141,300,473 (GRCm39) |
unclassified |
probably benign |
|
|
R6582:Muc2
|
UTSW |
7 |
141,282,941 (GRCm39) |
missense |
probably benign |
0.00 |
|
R6683:Muc2
|
UTSW |
7 |
141,305,214 (GRCm39) |
missense |
probably benign |
0.38 |
|
R6896:Muc2
|
UTSW |
7 |
141,306,432 (GRCm39) |
missense |
possibly damaging |
0.48 |
|
R6906:Muc2
|
UTSW |
7 |
141,284,976 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6924:Muc2
|
UTSW |
7 |
141,284,077 (GRCm39) |
missense |
possibly damaging |
0.87 |
|
R7040:Muc2
|
UTSW |
7 |
141,305,194 (GRCm39) |
missense |
unknown |
|
|
R7222:Muc2
|
UTSW |
7 |
141,290,758 (GRCm39) |
missense |
|
|
|
R7251:Muc2
|
UTSW |
7 |
141,278,965 (GRCm39) |
missense |
possibly damaging |
0.91 |
|
R7282:Muc2
|
UTSW |
7 |
141,306,481 (GRCm39) |
missense |
|
|
|
R7315:Muc2
|
UTSW |
7 |
141,276,645 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7421:Muc2
|
UTSW |
7 |
141,301,863 (GRCm39) |
missense |
|
|
|
R7556:Muc2
|
UTSW |
7 |
141,307,439 (GRCm39) |
missense |
|
|
|
R7651:Muc2
|
UTSW |
7 |
141,290,750 (GRCm39) |
missense |
|
|
|
R7710:Muc2
|
UTSW |
7 |
141,287,452 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R7776:Muc2
|
UTSW |
7 |
141,290,942 (GRCm39) |
missense |
|
|
|
R7813:Muc2
|
UTSW |
7 |
141,282,543 (GRCm39) |
splice site |
probably null |
|
|
R7843:Muc2
|
UTSW |
7 |
141,281,662 (GRCm39) |
missense |
probably benign |
0.03 |
|
R7869:Muc2
|
UTSW |
7 |
141,303,471 (GRCm39) |
missense |
|
|
|
R7924:Muc2
|
UTSW |
7 |
141,281,631 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7993:Muc2
|
UTSW |
7 |
141,308,173 (GRCm39) |
missense |
|
|
|
R8053:Muc2
|
UTSW |
7 |
141,284,575 (GRCm39) |
missense |
probably benign |
0.01 |
|
R8068:Muc2
|
UTSW |
7 |
141,298,422 (GRCm39) |
missense |
|
|
|
R8099:Muc2
|
UTSW |
7 |
141,299,175 (GRCm39) |
splice site |
probably null |
|
|
R8192:Muc2
|
UTSW |
7 |
141,305,215 (GRCm39) |
missense |
|
|
|
R8194:Muc2
|
UTSW |
7 |
141,290,801 (GRCm39) |
missense |
|
|
|
R8545:Muc2
|
UTSW |
7 |
141,306,130 (GRCm39) |
missense |
unknown |
|
|
R8701:Muc2
|
UTSW |
7 |
141,281,850 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8883:Muc2
|
UTSW |
7 |
141,287,469 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R8894:Muc2
|
UTSW |
7 |
141,280,758 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8905:Muc2
|
UTSW |
7 |
141,279,643 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9024:Muc2
|
UTSW |
7 |
141,287,936 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R9032:Muc2
|
UTSW |
7 |
141,287,058 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9085:Muc2
|
UTSW |
7 |
141,287,058 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9091:Muc2
|
UTSW |
7 |
141,290,816 (GRCm39) |
missense |
|
|
|
R9104:Muc2
|
UTSW |
7 |
141,286,224 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9114:Muc2
|
UTSW |
7 |
141,287,983 (GRCm39) |
nonsense |
probably null |
|
|
R9270:Muc2
|
UTSW |
7 |
141,290,816 (GRCm39) |
missense |
|
|
|
R9297:Muc2
|
UTSW |
7 |
141,302,759 (GRCm39) |
missense |
|
|
|
R9325:Muc2
|
UTSW |
7 |
141,298,559 (GRCm39) |
missense |
|
|
|
R9354:Muc2
|
UTSW |
7 |
141,307,157 (GRCm39) |
missense |
|
|
|
R9386:Muc2
|
UTSW |
7 |
141,279,389 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9529:Muc2
|
UTSW |
7 |
141,287,453 (GRCm39) |
missense |
possibly damaging |
0.55 |
|
R9550:Muc2
|
UTSW |
7 |
141,308,242 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9583:Muc2
|
UTSW |
7 |
141,300,559 (GRCm39) |
missense |
|
|
|
R9607:Muc2
|
UTSW |
7 |
141,305,190 (GRCm39) |
missense |
|
|
|
R9646:Muc2
|
UTSW |
7 |
141,276,643 (GRCm39) |
missense |
probably benign |
|
|
R9651:Muc2
|
UTSW |
7 |
141,288,014 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R9774:Muc2
|
UTSW |
7 |
141,285,811 (GRCm39) |
missense |
probably benign |
|
|
R9784:Muc2
|
UTSW |
7 |
141,280,785 (GRCm39) |
nonsense |
probably null |
|
|
Z1176:Muc2
|
UTSW |
7 |
141,300,451 (GRCm39) |
missense |
|
|
|
Z1177:Muc2
|
UTSW |
7 |
141,298,531 (GRCm39) |
missense |
|
|
|
| Predicted Primers |
PCR Primer
(F):5'- AGTTGGAGTCTATTCCCTTTGC -3'
(R):5'- ACCATTTGAGAGCCTCAGGTC -3'
Sequencing Primer
(F):5'- GGAGTCTATTCCCTTTGCCCCTTC -3'
(R):5'- ATTTGAGAGCCTCAGGTCCCATG -3'
|
| Posted On |
2017-06-26 |
Incidental Mutation