Incidental Mutation 'R6084:Arap2'
| ID |
482372 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Arap2
|
| Ensembl Gene |
ENSMUSG00000037999 |
| Gene Name |
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2 |
| Synonyms |
Centd1 |
| MMRRC Submission |
044243-MU
|
| Accession Numbers |
|
| Essential gene? |
Non essential
(E-score: 0.000)
|
| Stock # |
R6084 (G1)
|
| Quality Score |
225.009 |
|
Status
|
Not validated
|
| Chromosome |
5 |
| Chromosomal Location |
62759788-62923502 bp(-) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
T to C
at 62828297 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Aspartic acid to Glycine
at position 958
(D958G)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000075924
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000076623]
|
| AlphaFold |
no structure available at present |
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000076623
AA Change: D958G
PolyPhen 2
Score 0.893 (Sensitivity: 0.82; Specificity: 0.94)
|
| SMART Domains |
Protein: ENSMUSP00000075924
Gene: ENSMUSG00000037999
AA Change: D958G
| Domain | Start | End | E-Value | Type |
|---|
|
SAM
|
3 |
70 |
3.69e-7 |
SMART |
|
low complexity region
|
222 |
233 |
N/A |
INTRINSIC |
|
PH
|
481 |
574 |
6.45e-17 |
SMART |
|
PH
|
586 |
679 |
9.05e-12 |
SMART |
|
ArfGap
|
684 |
805 |
9.2e-33 |
SMART |
|
PH
|
891 |
1003 |
1.51e-8 |
SMART |
|
PH
|
1013 |
1112 |
9.21e-4 |
SMART |
|
RhoGAP
|
1124 |
1300 |
1.36e-50 |
SMART |
|
Pfam:RA
|
1325 |
1416 |
2.1e-7 |
PFAM |
|
PH
|
1429 |
1533 |
2.68e-14 |
SMART |
|
coiled coil region
|
1561 |
1590 |
N/A |
INTRINSIC |
|
| Coding Region Coverage |
- 1x: 99.9%
- 3x: 99.6%
- 10x: 98.2%
- 20x: 94.8%
|
| Validation Efficiency |
|
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] The protein encoded by this gene contains ARF-GAP, RHO-GAP, ankyrin repeat, RAS-associating, and pleckstrin homology domains. The protein is a phosphatidylinositol (3,4,5)-trisphosphate-dependent Arf6 GAP that binds RhoA-GTP, but it lacks the predicted catalytic arginine in the RHO-GAP domain and does not have RHO-GAP activity. The protein associates with focal adhesions and functions downstream of RhoA to regulate focal adhesion dynamics. [provided by RefSeq, Sep 2008]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 84 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Bag4 |
T |
C |
8: 26,261,259 (GRCm39) |
T161A |
probably benign |
Het |
| Bora |
A |
T |
14: 99,299,730 (GRCm39) |
Q234L |
possibly damaging |
Het |
| Cacna2d2 |
T |
C |
9: 107,374,720 (GRCm39) |
|
probably null |
Het |
| Cass4 |
G |
T |
2: 172,268,832 (GRCm39) |
A307S |
probably benign |
Het |
| Cbln4 |
A |
T |
2: 171,884,016 (GRCm39) |
V68E |
probably damaging |
Het |
| Cc2d2a |
T |
A |
5: 43,826,015 (GRCm39) |
N2K |
probably benign |
Het |
| Ccnf |
T |
A |
17: 24,450,811 (GRCm39) |
D389V |
probably damaging |
Het |
| Cdipt |
T |
C |
7: 126,578,773 (GRCm39) |
S161P |
probably benign |
Het |
| Ceacam19 |
T |
C |
7: 19,616,812 (GRCm39) |
I161V |
probably benign |
Het |
| Cfap65 |
A |
G |
1: 74,959,564 (GRCm39) |
I862T |
probably damaging |
Het |
| Cfi |
T |
A |
3: 129,652,019 (GRCm39) |
L230Q |
probably benign |
Het |
| Chac2 |
G |
A |
11: 30,936,159 (GRCm39) |
R30W |
probably damaging |
Het |
| Cmc2 |
G |
A |
8: 117,616,566 (GRCm39) |
|
probably benign |
Het |
| Col1a2 |
A |
T |
6: 4,505,840 (GRCm39) |
M1L |
probably benign |
Het |
| Cox8a |
C |
A |
19: 7,194,783 (GRCm39) |
R32L |
possibly damaging |
Het |
| Cubn |
T |
A |
2: 13,435,708 (GRCm39) |
N1083Y |
probably damaging |
Het |
| D630003M21Rik |
T |
C |
2: 158,059,504 (GRCm39) |
D132G |
probably damaging |
Het |
| Dedd2 |
G |
A |
7: 24,910,715 (GRCm39) |
P154S |
probably benign |
Het |
| Dnaaf3 |
T |
C |
7: 4,527,212 (GRCm39) |
D358G |
probably benign |
Het |
| Dysf |
T |
C |
6: 84,089,101 (GRCm39) |
L888P |
probably damaging |
Het |
| Dysf |
T |
A |
6: 83,996,586 (GRCm39) |
F29L |
probably damaging |
Het |
| Ebf4 |
A |
G |
2: 130,151,643 (GRCm39) |
D277G |
probably damaging |
Het |
| Ecm2 |
T |
A |
13: 49,668,570 (GRCm39) |
L91* |
probably null |
Het |
| Foxs1 |
T |
C |
2: 152,774,762 (GRCm39) |
D97G |
possibly damaging |
Het |
| Frs2 |
A |
C |
10: 116,912,714 (GRCm39) |
|
probably null |
Het |
| Grp |
A |
T |
18: 66,013,008 (GRCm39) |
D58V |
probably damaging |
Het |
| Hif1a |
T |
G |
12: 73,988,616 (GRCm39) |
F537C |
probably damaging |
Het |
| Icam4 |
G |
A |
9: 20,940,835 (GRCm39) |
S29N |
probably benign |
Het |
| Itfg1 |
T |
C |
8: 86,452,799 (GRCm39) |
E523G |
probably benign |
Het |
| Jph2 |
T |
C |
2: 163,217,600 (GRCm39) |
K359E |
probably damaging |
Het |
| Katnip |
G |
A |
7: 125,414,037 (GRCm39) |
G394R |
probably benign |
Het |
| Kcnq2 |
A |
T |
2: 180,729,449 (GRCm39) |
V490E |
possibly damaging |
Het |
| Klhl18 |
C |
T |
9: 110,257,795 (GRCm39) |
M548I |
possibly damaging |
Het |
| Lpin3 |
A |
G |
2: 160,737,721 (GRCm39) |
Y197C |
probably benign |
Het |
| Lrp1 |
T |
C |
10: 127,396,422 (GRCm39) |
N2381D |
probably benign |
Het |
| Man1a |
A |
T |
10: 53,795,307 (GRCm39) |
W649R |
probably damaging |
Het |
| Map4 |
T |
C |
9: 109,893,360 (GRCm39) |
L542P |
probably damaging |
Het |
| Mboat2 |
A |
T |
12: 24,928,284 (GRCm39) |
H52L |
probably damaging |
Het |
| Mok |
C |
G |
12: 110,781,380 (GRCm39) |
S91T |
probably benign |
Het |
| Mtmr11 |
G |
T |
3: 96,075,400 (GRCm39) |
R360L |
probably damaging |
Het |
| Myt1l |
G |
A |
12: 29,882,331 (GRCm39) |
G509R |
unknown |
Het |
| Ncoa4-ps |
A |
G |
12: 119,225,386 (GRCm39) |
|
noncoding transcript |
Het |
| Or1j13 |
A |
G |
2: 36,369,524 (GRCm39) |
V206A |
probably benign |
Het |
| Or4g7 |
A |
T |
2: 111,309,734 (GRCm39) |
N202Y |
probably damaging |
Het |
| Or52z1 |
C |
T |
7: 103,437,162 (GRCm39) |
M107I |
probably benign |
Het |
| Or55b4 |
T |
C |
7: 102,133,596 (GRCm39) |
T244A |
probably damaging |
Het |
| Or7d11 |
A |
T |
9: 19,966,179 (GRCm39) |
H75Q |
possibly damaging |
Het |
| Or7g21 |
A |
G |
9: 19,032,623 (GRCm39) |
D121G |
probably damaging |
Het |
| Padi3 |
G |
T |
4: 140,523,154 (GRCm39) |
T292N |
probably damaging |
Het |
| Pard6g |
A |
C |
18: 80,160,420 (GRCm39) |
T178P |
possibly damaging |
Het |
| Pkd1l2 |
A |
T |
8: 117,740,726 (GRCm39) |
Y2124N |
probably damaging |
Het |
| Plxdc1 |
G |
A |
11: 97,819,289 (GRCm39) |
T398I |
probably damaging |
Het |
| Prickle2 |
A |
T |
6: 92,393,829 (GRCm39) |
C225* |
probably null |
Het |
| Prmt2 |
G |
A |
10: 76,046,278 (GRCm39) |
T317I |
probably benign |
Het |
| Psg22 |
T |
G |
7: 18,453,705 (GRCm39) |
N172K |
probably benign |
Het |
| Ptpn9 |
C |
T |
9: 56,940,447 (GRCm39) |
R196* |
probably null |
Het |
| Rap1b |
C |
T |
10: 117,660,516 (GRCm39) |
V14I |
probably damaging |
Het |
| Rapgef4 |
T |
A |
2: 72,026,622 (GRCm39) |
|
probably null |
Het |
| Rlf |
A |
T |
4: 121,006,412 (GRCm39) |
M856K |
possibly damaging |
Het |
| Rnf149 |
A |
G |
1: 39,616,255 (GRCm39) |
L34P |
probably benign |
Het |
| Rock1 |
T |
C |
18: 10,101,007 (GRCm39) |
E636G |
probably benign |
Het |
| Rsad2 |
A |
T |
12: 26,504,122 (GRCm39) |
Y136N |
probably damaging |
Het |
| Ryr3 |
T |
C |
2: 112,738,838 (GRCm39) |
H563R |
probably damaging |
Het |
| Slc18b1 |
A |
G |
10: 23,680,110 (GRCm39) |
M102V |
probably benign |
Het |
| Slc34a2 |
T |
A |
5: 53,224,989 (GRCm39) |
C377S |
possibly damaging |
Het |
| Slco1c1 |
T |
C |
6: 141,492,496 (GRCm39) |
V293A |
probably benign |
Het |
| Spidr |
A |
T |
16: 15,957,888 (GRCm39) |
S80T |
possibly damaging |
Het |
| Syne1 |
C |
T |
10: 5,298,994 (GRCm39) |
E1031K |
probably damaging |
Het |
| Synj2 |
G |
A |
17: 6,067,889 (GRCm39) |
V121I |
probably damaging |
Het |
| Synj2 |
A |
T |
17: 6,088,373 (GRCm39) |
T1430S |
probably damaging |
Het |
| Tecpr2 |
G |
T |
12: 110,895,543 (GRCm39) |
K343N |
probably damaging |
Het |
| Tmem132d |
T |
A |
5: 127,861,164 (GRCm39) |
I986F |
probably benign |
Het |
| Trib1 |
G |
A |
15: 59,526,324 (GRCm39) |
R298H |
probably damaging |
Het |
| Ttll10 |
T |
A |
4: 156,129,814 (GRCm39) |
D283V |
probably benign |
Het |
| Ttn |
T |
A |
2: 76,645,123 (GRCm39) |
K673* |
probably null |
Het |
| Ubqlnl |
T |
A |
7: 103,797,905 (GRCm39) |
M531L |
probably benign |
Het |
| Vmn2r120 |
A |
T |
17: 57,832,721 (GRCm39) |
W153R |
probably benign |
Het |
| Vmn2r2 |
A |
C |
3: 64,024,467 (GRCm39) |
S705A |
probably benign |
Het |
| Vmn2r32 |
T |
A |
7: 7,467,209 (GRCm39) |
D773V |
probably benign |
Het |
| Vmn2r54 |
T |
A |
7: 12,366,205 (GRCm39) |
Q243L |
probably damaging |
Het |
| Wdr24 |
C |
A |
17: 26,043,504 (GRCm39) |
R109S |
probably damaging |
Het |
| Zfp113 |
T |
C |
5: 138,143,930 (GRCm39) |
M107V |
probably benign |
Het |
| Zfp426 |
G |
T |
9: 20,381,923 (GRCm39) |
Q341K |
possibly damaging |
Het |
| Zfp616 |
A |
T |
11: 73,974,672 (GRCm39) |
K314* |
probably null |
Het |
|
| Other mutations in Arap2 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00481:Arap2
|
APN |
5 |
62,793,305 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL00642:Arap2
|
APN |
5 |
62,890,401 (GRCm39) |
nonsense |
probably null |
|
|
IGL00705:Arap2
|
APN |
5 |
62,835,366 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL00942:Arap2
|
APN |
5 |
62,855,732 (GRCm39) |
nonsense |
probably null |
|
|
IGL01069:Arap2
|
APN |
5 |
62,807,199 (GRCm39) |
missense |
probably benign |
|
|
IGL01601:Arap2
|
APN |
5 |
62,798,685 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01986:Arap2
|
APN |
5 |
62,779,265 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02032:Arap2
|
APN |
5 |
62,828,340 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL02262:Arap2
|
APN |
5 |
62,800,184 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02331:Arap2
|
APN |
5 |
62,807,025 (GRCm39) |
splice site |
probably benign |
|
|
IGL02527:Arap2
|
APN |
5 |
62,906,650 (GRCm39) |
missense |
probably benign |
|
|
IGL02803:Arap2
|
APN |
5 |
62,906,452 (GRCm39) |
missense |
probably benign |
|
|
IGL02864:Arap2
|
APN |
5 |
62,835,308 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03078:Arap2
|
APN |
5 |
62,890,408 (GRCm39) |
splice site |
probably benign |
|
|
IGL03154:Arap2
|
APN |
5 |
62,800,268 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03213:Arap2
|
APN |
5 |
62,906,438 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL03279:Arap2
|
APN |
5 |
62,779,253 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03288:Arap2
|
APN |
5 |
62,761,959 (GRCm39) |
missense |
probably benign |
0.00 |
|
PIT4354001:Arap2
|
UTSW |
5 |
62,811,392 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0012:Arap2
|
UTSW |
5 |
62,840,827 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0013:Arap2
|
UTSW |
5 |
62,840,827 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0013:Arap2
|
UTSW |
5 |
62,840,827 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0166:Arap2
|
UTSW |
5 |
62,833,361 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0472:Arap2
|
UTSW |
5 |
62,864,002 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0506:Arap2
|
UTSW |
5 |
62,763,474 (GRCm39) |
missense |
possibly damaging |
0.87 |
|
R0551:Arap2
|
UTSW |
5 |
62,798,666 (GRCm39) |
splice site |
probably null |
|
|
R0607:Arap2
|
UTSW |
5 |
62,763,474 (GRCm39) |
missense |
possibly damaging |
0.87 |
|
R0617:Arap2
|
UTSW |
5 |
62,807,250 (GRCm39) |
splice site |
probably benign |
|
|
R0975:Arap2
|
UTSW |
5 |
62,888,229 (GRCm39) |
splice site |
probably benign |
|
|
R0976:Arap2
|
UTSW |
5 |
62,807,227 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1164:Arap2
|
UTSW |
5 |
62,840,820 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1268:Arap2
|
UTSW |
5 |
62,887,964 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1480:Arap2
|
UTSW |
5 |
62,826,472 (GRCm39) |
nonsense |
probably null |
|
|
R1502:Arap2
|
UTSW |
5 |
62,761,747 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1543:Arap2
|
UTSW |
5 |
62,763,498 (GRCm39) |
nonsense |
probably null |
|
|
R1865:Arap2
|
UTSW |
5 |
62,855,606 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R1962:Arap2
|
UTSW |
5 |
62,834,007 (GRCm39) |
missense |
possibly damaging |
0.82 |
|
R2040:Arap2
|
UTSW |
5 |
62,906,259 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R2118:Arap2
|
UTSW |
5 |
62,864,028 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2131:Arap2
|
UTSW |
5 |
62,835,301 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2201:Arap2
|
UTSW |
5 |
62,864,028 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2215:Arap2
|
UTSW |
5 |
62,834,519 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3027:Arap2
|
UTSW |
5 |
62,827,240 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3053:Arap2
|
UTSW |
5 |
62,906,200 (GRCm39) |
missense |
probably benign |
0.35 |
|
R3975:Arap2
|
UTSW |
5 |
62,906,237 (GRCm39) |
missense |
possibly damaging |
0.87 |
|
R4272:Arap2
|
UTSW |
5 |
62,828,322 (GRCm39) |
missense |
possibly damaging |
0.63 |
|
R4273:Arap2
|
UTSW |
5 |
62,828,322 (GRCm39) |
missense |
possibly damaging |
0.63 |
|
R4326:Arap2
|
UTSW |
5 |
62,779,206 (GRCm39) |
missense |
possibly damaging |
0.50 |
|
R4327:Arap2
|
UTSW |
5 |
62,779,206 (GRCm39) |
missense |
possibly damaging |
0.50 |
|
R4328:Arap2
|
UTSW |
5 |
62,779,206 (GRCm39) |
missense |
possibly damaging |
0.50 |
|
R4451:Arap2
|
UTSW |
5 |
62,906,513 (GRCm39) |
missense |
probably benign |
0.06 |
|
R4659:Arap2
|
UTSW |
5 |
62,811,469 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R4665:Arap2
|
UTSW |
5 |
62,827,312 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R4715:Arap2
|
UTSW |
5 |
62,906,437 (GRCm39) |
missense |
probably benign |
0.43 |
|
R4808:Arap2
|
UTSW |
5 |
62,887,984 (GRCm39) |
missense |
probably benign |
0.23 |
|
R4941:Arap2
|
UTSW |
5 |
62,906,821 (GRCm39) |
missense |
probably benign |
0.20 |
|
R4983:Arap2
|
UTSW |
5 |
62,833,868 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R5095:Arap2
|
UTSW |
5 |
62,811,392 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5156:Arap2
|
UTSW |
5 |
62,826,524 (GRCm39) |
nonsense |
probably null |
|
|
R5201:Arap2
|
UTSW |
5 |
62,840,832 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5346:Arap2
|
UTSW |
5 |
62,872,089 (GRCm39) |
missense |
probably benign |
0.39 |
|
R5359:Arap2
|
UTSW |
5 |
62,840,762 (GRCm39) |
nonsense |
probably null |
|
|
R5426:Arap2
|
UTSW |
5 |
62,800,159 (GRCm39) |
missense |
probably benign |
0.02 |
|
R5503:Arap2
|
UTSW |
5 |
62,787,529 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5605:Arap2
|
UTSW |
5 |
62,772,410 (GRCm39) |
missense |
possibly damaging |
0.47 |
|
R5764:Arap2
|
UTSW |
5 |
62,800,197 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5813:Arap2
|
UTSW |
5 |
62,834,506 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5846:Arap2
|
UTSW |
5 |
62,807,116 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6173:Arap2
|
UTSW |
5 |
62,906,965 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6175:Arap2
|
UTSW |
5 |
62,872,074 (GRCm39) |
critical splice donor site |
probably null |
|
|
R6249:Arap2
|
UTSW |
5 |
62,803,536 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R6386:Arap2
|
UTSW |
5 |
62,761,865 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R6424:Arap2
|
UTSW |
5 |
62,840,707 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6744:Arap2
|
UTSW |
5 |
62,906,281 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6766:Arap2
|
UTSW |
5 |
62,834,443 (GRCm39) |
critical splice donor site |
probably null |
|
|
R6990:Arap2
|
UTSW |
5 |
62,833,860 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R7067:Arap2
|
UTSW |
5 |
62,811,387 (GRCm39) |
critical splice donor site |
probably null |
|
|
R7098:Arap2
|
UTSW |
5 |
62,833,293 (GRCm39) |
critical splice donor site |
probably null |
|
|
R7107:Arap2
|
UTSW |
5 |
62,763,551 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R7156:Arap2
|
UTSW |
5 |
62,761,914 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7174:Arap2
|
UTSW |
5 |
62,761,621 (GRCm39) |
missense |
probably benign |
|
|
R7187:Arap2
|
UTSW |
5 |
62,826,396 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7197:Arap2
|
UTSW |
5 |
62,798,729 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R7214:Arap2
|
UTSW |
5 |
62,906,681 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7317:Arap2
|
UTSW |
5 |
62,807,067 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7392:Arap2
|
UTSW |
5 |
62,855,728 (GRCm39) |
missense |
possibly damaging |
0.54 |
|
R7438:Arap2
|
UTSW |
5 |
62,906,818 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7452:Arap2
|
UTSW |
5 |
62,833,892 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7495:Arap2
|
UTSW |
5 |
62,833,893 (GRCm39) |
missense |
possibly damaging |
0.78 |
|
R7796:Arap2
|
UTSW |
5 |
62,888,105 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7936:Arap2
|
UTSW |
5 |
62,888,048 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R8116:Arap2
|
UTSW |
5 |
62,887,954 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8172:Arap2
|
UTSW |
5 |
62,779,324 (GRCm39) |
splice site |
probably null |
|
|
R8277:Arap2
|
UTSW |
5 |
62,771,335 (GRCm39) |
critical splice donor site |
probably null |
|
|
R8369:Arap2
|
UTSW |
5 |
62,761,669 (GRCm39) |
nonsense |
probably null |
|
|
R8398:Arap2
|
UTSW |
5 |
62,906,252 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8893:Arap2
|
UTSW |
5 |
62,888,037 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8973:Arap2
|
UTSW |
5 |
62,855,668 (GRCm39) |
nonsense |
probably null |
|
|
R9102:Arap2
|
UTSW |
5 |
62,906,341 (GRCm39) |
missense |
probably benign |
0.03 |
|
R9121:Arap2
|
UTSW |
5 |
62,906,326 (GRCm39) |
missense |
possibly damaging |
0.84 |
|
R9174:Arap2
|
UTSW |
5 |
62,855,606 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9222:Arap2
|
UTSW |
5 |
62,828,421 (GRCm39) |
missense |
possibly damaging |
0.96 |
|
R9281:Arap2
|
UTSW |
5 |
62,906,848 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R9399:Arap2
|
UTSW |
5 |
62,763,455 (GRCm39) |
missense |
possibly damaging |
0.62 |
|
R9450:Arap2
|
UTSW |
5 |
62,855,762 (GRCm39) |
missense |
probably benign |
0.16 |
|
R9467:Arap2
|
UTSW |
5 |
62,887,900 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9567:Arap2
|
UTSW |
5 |
62,761,841 (GRCm39) |
missense |
probably benign |
0.01 |
|
R9577:Arap2
|
UTSW |
5 |
62,769,060 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9626:Arap2
|
UTSW |
5 |
62,906,878 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9688:Arap2
|
UTSW |
5 |
62,872,109 (GRCm39) |
missense |
probably damaging |
0.98 |
|
| Predicted Primers |
PCR Primer
(F):5'- AAGTACGTTTTAGAGAATGTCCTGTGG -3'
(R):5'- TTACTTGAATGCAGTCGTGATGTTC -3'
|
| Posted On |
2017-07-14 |
Incidental Mutation