Incidental Mutation 'R6052:Dennd4a'
| ID |
484165 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Dennd4a
|
| Ensembl Gene |
ENSMUSG00000053641 |
| Gene Name |
DENN/MADD domain containing 4A |
| Synonyms |
F730015K02Rik |
| MMRRC Submission |
044220-MU
|
| Accession Numbers |
|
| Essential gene? |
Possibly non essential
(E-score: 0.432)
|
| Stock # |
R6052 (G1)
|
| Quality Score |
225.009 |
|
Status
|
Validated
|
| Chromosome |
9 |
| Chromosomal Location |
64811340-64919667 bp(+) (GRCm38) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
A to G
at 64886945 bp (GRCm38)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Glutamic Acid to Glycine
at position 682
(E682G)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000037915
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000038890]
|
| AlphaFold |
E9Q8V6 |
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000038890
AA Change: E682G
PolyPhen 2
Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)
|
| SMART Domains |
Protein: ENSMUSP00000037915
Gene: ENSMUSG00000053641
AA Change: E682G
| Domain | Start | End | E-Value | Type |
|---|
|
internal_repeat_1
|
45 |
93 |
3.26e-5 |
PROSPERO |
|
uDENN
|
169 |
276 |
1.71e-28 |
SMART |
|
DENN
|
309 |
493 |
2.4e-73 |
SMART |
|
dDENN
|
559 |
633 |
4.15e-27 |
SMART |
|
low complexity region
|
724 |
735 |
N/A |
INTRINSIC |
|
low complexity region
|
936 |
950 |
N/A |
INTRINSIC |
|
low complexity region
|
1176 |
1191 |
N/A |
INTRINSIC |
|
low complexity region
|
1249 |
1262 |
N/A |
INTRINSIC |
|
low complexity region
|
1402 |
1417 |
N/A |
INTRINSIC |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000216098
|
| Meta Mutation Damage Score |
0.6589 |
| Coding Region Coverage |
- 1x: 99.9%
- 3x: 99.6%
- 10x: 98.2%
- 20x: 94.7%
|
| Validation Efficiency |
96% (80/83) |
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene encodes a DENN domain-containing protein that may function as a guanine nucleotide exchange factor that specifically activates ras-related protein Rab-10. This protein also contains a interferon stimulated response element-binding domain and may be involved in regulating the v-myc avian myelocytomatosis viral (MYC) oncogene. Alternate splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome 8. [provided by RefSeq, Mar 2016]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 80 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Abca17 |
A |
G |
17: 24,318,191 (GRCm38) |
F473L |
probably benign |
Het |
| Ankrd17 |
T |
C |
5: 90,253,832 (GRCm38) |
I1449V |
probably benign |
Het |
| Aox4 |
T |
A |
1: 58,254,318 (GRCm38) |
L943* |
probably null |
Het |
| Arap1 |
G |
A |
7: 101,404,033 (GRCm38) |
V1257M |
probably damaging |
Het |
| B3gnt9 |
T |
C |
8: 105,254,598 (GRCm38) |
S53G |
probably benign |
Het |
| Baiap3 |
A |
T |
17: 25,248,470 (GRCm38) |
|
probably benign |
Het |
| Canx |
T |
C |
11: 50,297,119 (GRCm38) |
D554G |
possibly damaging |
Het |
| Cbfa2t2 |
T |
C |
2: 154,510,581 (GRCm38) |
V165A |
probably damaging |
Het |
| Ccdc17 |
C |
T |
4: 116,599,948 (GRCm38) |
|
probably null |
Het |
| Cdcp1 |
A |
G |
9: 123,185,331 (GRCm38) |
I126T |
probably benign |
Het |
| Cdk13 |
A |
T |
13: 17,721,215 (GRCm38) |
D1036E |
probably damaging |
Het |
| Cfap157 |
A |
G |
2: 32,779,851 (GRCm38) |
L240P |
probably damaging |
Het |
| Clec18a |
C |
A |
8: 111,078,816 (GRCm38) |
E218* |
probably null |
Het |
| Col3a1 |
T |
C |
1: 45,345,013 (GRCm38) |
|
probably benign |
Het |
| Dnah14 |
T |
C |
1: 181,666,487 (GRCm38) |
V1736A |
possibly damaging |
Het |
| Dpep2 |
T |
A |
8: 105,990,638 (GRCm38) |
D162V |
possibly damaging |
Het |
| Drd3 |
C |
A |
16: 43,821,283 (GRCm38) |
P321T |
probably benign |
Het |
| Egfr |
A |
G |
11: 16,911,554 (GRCm38) |
H1111R |
probably benign |
Het |
| Entpd1 |
T |
C |
19: 40,720,484 (GRCm38) |
S58P |
probably damaging |
Het |
| Epha3 |
C |
A |
16: 63,603,604 (GRCm38) |
V541L |
possibly damaging |
Het |
| Eri3 |
T |
A |
4: 117,564,628 (GRCm38) |
D34E |
probably damaging |
Het |
| Eya1 |
T |
C |
1: 14,283,150 (GRCm38) |
D58G |
probably damaging |
Het |
| Fat3 |
T |
A |
9: 15,922,679 (GRCm38) |
S26C |
probably null |
Het |
| Fgl1 |
T |
C |
8: 41,200,511 (GRCm38) |
D115G |
probably damaging |
Het |
| Fitm2 |
T |
C |
2: 163,470,116 (GRCm38) |
Y59C |
probably damaging |
Het |
| Fras1 |
T |
A |
5: 96,764,866 (GRCm38) |
I3343N |
probably damaging |
Het |
| Gba2 |
C |
A |
4: 43,568,330 (GRCm38) |
C679F |
probably damaging |
Het |
| Glis2 |
G |
A |
16: 4,613,739 (GRCm38) |
|
probably benign |
Het |
| Gm13088 |
T |
A |
4: 143,655,652 (GRCm38) |
D158V |
probably damaging |
Het |
| Gm5150 |
T |
A |
3: 15,990,753 (GRCm38) |
I103F |
probably damaging |
Het |
| H2-Ke6 |
A |
G |
17: 34,027,455 (GRCm38) |
L118P |
probably damaging |
Het |
| Hhipl2 |
T |
C |
1: 183,424,057 (GRCm38) |
S313P |
possibly damaging |
Het |
| Hmgcs1 |
A |
G |
13: 119,705,459 (GRCm38) |
D474G |
probably benign |
Het |
| Homer3 |
C |
T |
8: 70,291,426 (GRCm38) |
Q267* |
probably null |
Het |
| Igkv8-28 |
C |
T |
6: 70,143,689 (GRCm38) |
G90D |
probably damaging |
Het |
| Kalrn |
T |
A |
16: 34,360,885 (GRCm38) |
I128F |
probably damaging |
Het |
| Krt4 |
A |
G |
15: 101,922,759 (GRCm38) |
|
probably null |
Het |
| Lamb2 |
T |
A |
9: 108,487,612 (GRCm38) |
C1188* |
probably null |
Het |
| Lsr |
A |
T |
7: 30,958,617 (GRCm38) |
M355K |
probably damaging |
Het |
| Map3k11 |
T |
G |
19: 5,697,402 (GRCm38) |
D555E |
probably benign |
Het |
| Myocd |
A |
G |
11: 65,196,256 (GRCm38) |
Y282H |
probably damaging |
Het |
| Nae1 |
T |
C |
8: 104,534,544 (GRCm38) |
I7M |
probably benign |
Het |
| Nprl3 |
G |
T |
11: 32,255,453 (GRCm38) |
H102N |
possibly damaging |
Het |
| Nup62 |
T |
A |
7: 44,829,040 (GRCm38) |
F160I |
possibly damaging |
Het |
| Olfr1490 |
C |
A |
19: 13,654,507 (GRCm38) |
P26Q |
possibly damaging |
Het |
| Olfr456 |
T |
A |
6: 42,486,654 (GRCm38) |
T180S |
possibly damaging |
Het |
| Olfr502 |
A |
G |
7: 108,523,738 (GRCm38) |
S71P |
probably benign |
Het |
| Olfr709-ps1 |
A |
T |
7: 106,926,689 (GRCm38) |
F257I |
probably benign |
Het |
| Olfr781 |
C |
A |
10: 129,333,202 (GRCm38) |
T107K |
possibly damaging |
Het |
| Osbpl10 |
T |
C |
9: 115,067,315 (GRCm38) |
|
probably null |
Het |
| Pcdh9 |
C |
T |
14: 93,885,846 (GRCm38) |
V963I |
probably benign |
Het |
| Phf12 |
A |
G |
11: 78,018,218 (GRCm38) |
R375G |
probably benign |
Het |
| Piezo1 |
G |
A |
8: 122,506,269 (GRCm38) |
T108M |
probably damaging |
Het |
| Plxnc1 |
T |
A |
10: 94,943,773 (GRCm38) |
Q269L |
probably benign |
Het |
| Pomgnt1 |
T |
A |
4: 116,151,602 (GRCm38) |
N11K |
possibly damaging |
Het |
| Prkd1 |
A |
T |
12: 50,366,300 (GRCm38) |
|
probably null |
Het |
| Prpf40a |
T |
C |
2: 53,159,281 (GRCm38) |
T190A |
probably benign |
Het |
| Prrc2b |
A |
C |
2: 32,212,285 (GRCm38) |
H790P |
possibly damaging |
Het |
| Rest |
T |
G |
5: 77,281,180 (GRCm38) |
V482G |
probably benign |
Het |
| Ros1 |
T |
A |
10: 52,163,903 (GRCm38) |
I322L |
probably benign |
Het |
| Rpl18 |
G |
A |
7: 45,720,130 (GRCm38) |
|
probably benign |
Het |
| Rsad2 |
G |
A |
12: 26,450,578 (GRCm38) |
H237Y |
probably benign |
Het |
| Sbf2 |
A |
G |
7: 110,441,534 (GRCm38) |
L362S |
probably damaging |
Het |
| Sgsm3 |
A |
G |
15: 81,009,263 (GRCm38) |
T409A |
probably benign |
Het |
| Slc16a14 |
T |
C |
1: 84,912,709 (GRCm38) |
T292A |
possibly damaging |
Het |
| Spg11 |
T |
G |
2: 122,097,356 (GRCm38) |
K649T |
probably damaging |
Het |
| Srprb |
T |
A |
9: 103,190,216 (GRCm38) |
I268F |
possibly damaging |
Het |
| Tap2 |
G |
A |
17: 34,214,709 (GRCm38) |
G566S |
probably damaging |
Het |
| Tecpr2 |
T |
C |
12: 110,918,891 (GRCm38) |
V168A |
possibly damaging |
Het |
| Tln1 |
G |
C |
4: 43,555,052 (GRCm38) |
F259L |
probably damaging |
Het |
| Tmem181a |
T |
A |
17: 6,280,615 (GRCm38) |
L50H |
probably damaging |
Het |
| Tshz1 |
A |
G |
18: 84,014,069 (GRCm38) |
I738T |
probably damaging |
Het |
| Tspan12 |
T |
C |
6: 21,772,638 (GRCm38) |
E304G |
probably benign |
Het |
| Urb1 |
C |
T |
16: 90,762,383 (GRCm38) |
G1671S |
probably damaging |
Het |
| Vmn2r2 |
T |
C |
3: 64,117,361 (GRCm38) |
S600G |
possibly damaging |
Het |
| Wnt3 |
C |
A |
11: 103,808,174 (GRCm38) |
Y35* |
probably null |
Het |
| Xpo7 |
T |
C |
14: 70,683,719 (GRCm38) |
Y603C |
possibly damaging |
Het |
| Zfp457 |
G |
A |
13: 67,293,951 (GRCm38) |
H91Y |
probably damaging |
Het |
| Zfp664 |
T |
A |
5: 124,886,186 (GRCm38) |
C215S |
unknown |
Het |
| Zfp882 |
G |
A |
8: 71,914,505 (GRCm38) |
G392D |
probably benign |
Het |
|
| Other mutations in Dennd4a |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00476:Dennd4a
|
APN |
9 |
64,911,762 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL01610:Dennd4a
|
APN |
9 |
64,906,884 (GRCm38) |
missense |
probably damaging |
0.99 |
|
IGL01788:Dennd4a
|
APN |
9 |
64,842,621 (GRCm38) |
missense |
probably benign |
0.00 |
|
IGL01827:Dennd4a
|
APN |
9 |
64,842,561 (GRCm38) |
nonsense |
probably null |
|
|
IGL01828:Dennd4a
|
APN |
9 |
64,842,561 (GRCm38) |
nonsense |
probably null |
|
|
IGL01829:Dennd4a
|
APN |
9 |
64,842,561 (GRCm38) |
nonsense |
probably null |
|
|
IGL01979:Dennd4a
|
APN |
9 |
64,894,409 (GRCm38) |
missense |
probably benign |
0.00 |
|
IGL02100:Dennd4a
|
APN |
9 |
64,909,706 (GRCm38) |
splice site |
probably benign |
|
|
IGL02339:Dennd4a
|
APN |
9 |
64,842,561 (GRCm38) |
nonsense |
probably null |
|
|
IGL02341:Dennd4a
|
APN |
9 |
64,842,561 (GRCm38) |
nonsense |
probably null |
|
|
IGL02584:Dennd4a
|
APN |
9 |
64,851,298 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL02607:Dennd4a
|
APN |
9 |
64,862,327 (GRCm38) |
missense |
probably damaging |
0.99 |
|
IGL02654:Dennd4a
|
APN |
9 |
64,910,191 (GRCm38) |
splice site |
probably benign |
|
|
IGL02701:Dennd4a
|
APN |
9 |
64,897,353 (GRCm38) |
missense |
possibly damaging |
0.50 |
|
IGL03051:Dennd4a
|
APN |
9 |
64,862,414 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL03257:Dennd4a
|
APN |
9 |
64,871,874 (GRCm38) |
missense |
possibly damaging |
0.93 |
|
IGL03346:Dennd4a
|
APN |
9 |
64,888,526 (GRCm38) |
missense |
possibly damaging |
0.47 |
|
IGL03349:Dennd4a
|
APN |
9 |
64,888,974 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL03398:Dennd4a
|
APN |
9 |
64,871,882 (GRCm38) |
missense |
probably benign |
0.32 |
|
R0010:Dennd4a
|
UTSW |
9 |
64,896,715 (GRCm38) |
missense |
probably benign |
0.00 |
|
R0010:Dennd4a
|
UTSW |
9 |
64,896,715 (GRCm38) |
missense |
probably benign |
0.00 |
|
R0129:Dennd4a
|
UTSW |
9 |
64,893,294 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R0220:Dennd4a
|
UTSW |
9 |
64,852,445 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R0396:Dennd4a
|
UTSW |
9 |
64,862,391 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R0881:Dennd4a
|
UTSW |
9 |
64,851,383 (GRCm38) |
critical splice donor site |
probably null |
|
|
R1225:Dennd4a
|
UTSW |
9 |
64,911,675 (GRCm38) |
missense |
probably benign |
0.03 |
|
R1311:Dennd4a
|
UTSW |
9 |
64,910,004 (GRCm38) |
missense |
probably benign |
0.34 |
|
R1448:Dennd4a
|
UTSW |
9 |
64,906,045 (GRCm38) |
missense |
possibly damaging |
0.95 |
|
R1450:Dennd4a
|
UTSW |
9 |
64,911,665 (GRCm38) |
missense |
probably benign |
0.03 |
|
R1630:Dennd4a
|
UTSW |
9 |
64,871,882 (GRCm38) |
missense |
probably benign |
0.32 |
|
R1709:Dennd4a
|
UTSW |
9 |
64,889,605 (GRCm38) |
missense |
possibly damaging |
0.92 |
|
R1824:Dennd4a
|
UTSW |
9 |
64,859,358 (GRCm38) |
critical splice donor site |
probably null |
|
|
R1851:Dennd4a
|
UTSW |
9 |
64,862,030 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R1870:Dennd4a
|
UTSW |
9 |
64,897,234 (GRCm38) |
missense |
probably benign |
0.00 |
|
R1900:Dennd4a
|
UTSW |
9 |
64,897,336 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R1911:Dennd4a
|
UTSW |
9 |
64,889,086 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R1938:Dennd4a
|
UTSW |
9 |
64,842,490 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R1954:Dennd4a
|
UTSW |
9 |
64,852,467 (GRCm38) |
missense |
probably benign |
0.02 |
|
R1955:Dennd4a
|
UTSW |
9 |
64,852,467 (GRCm38) |
missense |
probably benign |
0.02 |
|
R2049:Dennd4a
|
UTSW |
9 |
64,889,605 (GRCm38) |
missense |
possibly damaging |
0.92 |
|
R2129:Dennd4a
|
UTSW |
9 |
64,905,974 (GRCm38) |
splice site |
probably null |
|
|
R2138:Dennd4a
|
UTSW |
9 |
64,889,337 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R2929:Dennd4a
|
UTSW |
9 |
64,852,417 (GRCm38) |
missense |
possibly damaging |
0.85 |
|
R3083:Dennd4a
|
UTSW |
9 |
64,906,081 (GRCm38) |
missense |
probably benign |
0.03 |
|
R3108:Dennd4a
|
UTSW |
9 |
64,912,387 (GRCm38) |
missense |
probably benign |
0.23 |
|
R3176:Dennd4a
|
UTSW |
9 |
64,888,993 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R3177:Dennd4a
|
UTSW |
9 |
64,888,993 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R3276:Dennd4a
|
UTSW |
9 |
64,888,993 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R3277:Dennd4a
|
UTSW |
9 |
64,888,993 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R3890:Dennd4a
|
UTSW |
9 |
64,872,028 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R3953:Dennd4a
|
UTSW |
9 |
64,852,575 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R3963:Dennd4a
|
UTSW |
9 |
64,862,331 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4059:Dennd4a
|
UTSW |
9 |
64,911,892 (GRCm38) |
missense |
possibly damaging |
0.92 |
|
R4499:Dennd4a
|
UTSW |
9 |
64,910,123 (GRCm38) |
missense |
possibly damaging |
0.78 |
|
R4500:Dennd4a
|
UTSW |
9 |
64,910,123 (GRCm38) |
missense |
possibly damaging |
0.78 |
|
R4501:Dennd4a
|
UTSW |
9 |
64,910,123 (GRCm38) |
missense |
possibly damaging |
0.78 |
|
R4671:Dennd4a
|
UTSW |
9 |
64,894,407 (GRCm38) |
missense |
probably benign |
|
|
R4701:Dennd4a
|
UTSW |
9 |
64,897,357 (GRCm38) |
missense |
possibly damaging |
0.91 |
|
R4821:Dennd4a
|
UTSW |
9 |
64,897,249 (GRCm38) |
missense |
possibly damaging |
0.92 |
|
R4829:Dennd4a
|
UTSW |
9 |
64,889,056 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4876:Dennd4a
|
UTSW |
9 |
64,896,590 (GRCm38) |
missense |
probably benign |
|
|
R4881:Dennd4a
|
UTSW |
9 |
64,838,844 (GRCm38) |
missense |
possibly damaging |
0.77 |
|
R4962:Dennd4a
|
UTSW |
9 |
64,906,003 (GRCm38) |
missense |
probably benign |
0.00 |
|
R5225:Dennd4a
|
UTSW |
9 |
64,888,928 (GRCm38) |
missense |
possibly damaging |
0.94 |
|
R5557:Dennd4a
|
UTSW |
9 |
64,904,227 (GRCm38) |
missense |
probably benign |
0.07 |
|
R5649:Dennd4a
|
UTSW |
9 |
64,851,209 (GRCm38) |
splice site |
probably null |
|
|
R5868:Dennd4a
|
UTSW |
9 |
64,896,729 (GRCm38) |
missense |
probably benign |
0.02 |
|
R5876:Dennd4a
|
UTSW |
9 |
64,911,755 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R6411:Dennd4a
|
UTSW |
9 |
64,871,899 (GRCm38) |
missense |
probably benign |
0.04 |
|
R6596:Dennd4a
|
UTSW |
9 |
64,852,420 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R6668:Dennd4a
|
UTSW |
9 |
64,886,965 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R6915:Dennd4a
|
UTSW |
9 |
64,852,489 (GRCm38) |
nonsense |
probably null |
|
|
R7056:Dennd4a
|
UTSW |
9 |
64,906,923 (GRCm38) |
missense |
possibly damaging |
0.89 |
|
R7107:Dennd4a
|
UTSW |
9 |
64,894,399 (GRCm38) |
missense |
possibly damaging |
0.79 |
|
R7203:Dennd4a
|
UTSW |
9 |
64,896,474 (GRCm38) |
missense |
probably benign |
0.05 |
|
R7238:Dennd4a
|
UTSW |
9 |
64,861,956 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R7373:Dennd4a
|
UTSW |
9 |
64,897,269 (GRCm38) |
missense |
probably benign |
0.01 |
|
R7454:Dennd4a
|
UTSW |
9 |
64,852,570 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R7546:Dennd4a
|
UTSW |
9 |
64,873,044 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R7590:Dennd4a
|
UTSW |
9 |
64,888,587 (GRCm38) |
missense |
probably benign |
0.01 |
|
R7662:Dennd4a
|
UTSW |
9 |
64,852,431 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R7782:Dennd4a
|
UTSW |
9 |
64,906,920 (GRCm38) |
missense |
probably damaging |
0.98 |
|
R7909:Dennd4a
|
UTSW |
9 |
64,872,993 (GRCm38) |
critical splice acceptor site |
probably null |
|
|
R7976:Dennd4a
|
UTSW |
9 |
64,852,512 (GRCm38) |
missense |
possibly damaging |
0.95 |
|
R8026:Dennd4a
|
UTSW |
9 |
64,873,030 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R8034:Dennd4a
|
UTSW |
9 |
64,888,568 (GRCm38) |
missense |
probably benign |
0.01 |
|
R8089:Dennd4a
|
UTSW |
9 |
64,849,175 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R8298:Dennd4a
|
UTSW |
9 |
64,906,875 (GRCm38) |
missense |
probably benign |
0.00 |
|
R8397:Dennd4a
|
UTSW |
9 |
64,889,109 (GRCm38) |
missense |
probably benign |
|
|
R8425:Dennd4a
|
UTSW |
9 |
64,838,974 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R8495:Dennd4a
|
UTSW |
9 |
64,886,879 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R8855:Dennd4a
|
UTSW |
9 |
64,912,390 (GRCm38) |
missense |
probably benign |
|
|
R9219:Dennd4a
|
UTSW |
9 |
64,889,094 (GRCm38) |
missense |
probably damaging |
0.96 |
|
R9275:Dennd4a
|
UTSW |
9 |
64,842,624 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R9376:Dennd4a
|
UTSW |
9 |
64,912,692 (GRCm38) |
missense |
probably benign |
0.00 |
|
R9485:Dennd4a
|
UTSW |
9 |
64,907,106 (GRCm38) |
nonsense |
probably null |
|
|
R9672:Dennd4a
|
UTSW |
9 |
64,893,358 (GRCm38) |
missense |
probably benign |
|
|
R9746:Dennd4a
|
UTSW |
9 |
64,894,511 (GRCm38) |
missense |
probably benign |
|
|
X0026:Dennd4a
|
UTSW |
9 |
64,897,320 (GRCm38) |
missense |
possibly damaging |
0.67 |
|
Z1088:Dennd4a
|
UTSW |
9 |
64,872,022 (GRCm38) |
missense |
probably damaging |
1.00 |
|
| Predicted Primers |
PCR Primer
(F):5'- ATGTTTCAGCAGGTTAGGGTAC -3'
(R):5'- GGATAGGCTTGCTTACCACC -3'
Sequencing Primer
(F):5'- CAGCAGGTTAGGGTACTTTTTAAAG -3'
(R):5'- GGCTTGCTTACCACCTAAAAATTAG -3'
|
| Posted On |
2017-07-14 |
Incidental Mutation