Mutagenetix > Incidental Mutation

Incidental Mutation 'R6056:Dnah3'

484399

Institutional Source

Beutler Lab

Gene Symbol

Dnah3

Ensembl Gene

ENSMUSG00000052273

Gene Name

dynein, axonemal, heavy chain 3

Synonyms

MMRRC Submission

044223-MU

Accession Numbers

Essential gene?

Probably non essential (E-score: 0.089) question?

Stock #

R6056 (G1)

Quality Score

225.009

Status

Validated

Chromosome

Chromosomal Location

119922671-120095280 bp(-) (GRCm38)

Type of Mutation

missense

DNA Base Change (assembly)

A to G at 120030031 bp (GRCm38)

Zygosity

Heterozygous

Amino Acid Change

Phenylalanine to Leucine at position 1434 (F1434L)

Ref Sequence

ENSEMBL: ENSMUSP00000042857 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000046993] [ENSMUST00000209154] [ENSMUST00000213149]

AlphaFold

no structure available at present

Predicted Effect

probably damaging
Transcript: ENSMUST00000046993
AA Change: F1434L

PolyPhen 2 Score 0.998 (Sensitivity: 0.27; Specificity: 0.99)

SMART Domains

Protein: ENSMUSP00000042857
Gene: ENSMUSG00000052273
AA Change: F1434L

Domain	Start	End	E-Value	Type
low complexity region	121	133	N/A	INTRINSIC
low complexity region	805	820	N/A	INTRINSIC
Pfam:DHC_N2	826	1235	3.3e-144	PFAM
AAA	1388	1527	1.59e-1	SMART
low complexity region	1594	1606	N/A	INTRINSIC
Blast:AAA	1669	1897	9e-84	BLAST
AAA	2033	2180	1.33e-3	SMART
Pfam:AAA_8	2362	2632	1.5e-63	PFAM
Pfam:MT	2644	2994	7.4e-52	PFAM
Pfam:AAA_9	3015	3240	3.5e-92	PFAM
low complexity region	3338	3349	N/A	INTRINSIC
Pfam:Dynein_heavy	3376	4079	4.4e-285	PFAM

Predicted Effect

possibly damaging
Transcript: ENSMUST00000209154
AA Change: F1423L

PolyPhen 2 Score 0.946 (Sensitivity: 0.80; Specificity: 0.95)

Predicted Effect

probably benign
Transcript: ENSMUST00000213149

Meta Mutation Damage Score

0.3488

Coding Region Coverage

1x: 99.9%
3x: 99.7%
10x: 98.4%
20x: 95.4%

Validation Efficiency

96% (99/103)

MGI Phenotype

FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene belongs to the dynein family, whose members encode large proteins that are constituents of the microtubule-associated motor protein complex. This complex is composed of dynein heavy, intermediate and light chains, which can be axonemal or cytoplasmic. This protein is an axonemal dynein heavy chain. It is involved in producing force for ciliary beating by using energy from ATP hydrolysis. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Dec 2016]

Allele List at MGI

Other mutations in this stock

Total: 101 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
2310002L09Rik	A	T	4: 73,942,878	W162R	probably benign	Het
2610507B11Rik	C	A	11: 78,271,384	L691I	possibly damaging	Het
4930438A08Rik	C	A	11: 58,293,638	P394H	probably damaging	Het
Aggf1	C	T	13: 95,371,615	C81Y	probably benign	Het
Agxt2	A	T	15: 10,378,877	D188V	probably damaging	Het
Angpt2	T	C	8: 18,698,116	K376R	probably benign	Het
Anxa5	A	G	3: 36,450,691	S241P	probably damaging	Het
Aox3	A	T	1: 58,169,859	K850N	probably damaging	Het
Arid5a	T	C	1: 36,319,392	M415T	probably benign	Het
Aspa	T	A	11: 73,308,752	N233I	probably damaging	Het
Atp4b	C	T	8: 13,388,782	R198Q	probably damaging	Het
Atp8b2	A	T	3: 89,946,221	V719E	possibly damaging	Het
Cacna1s	T	G	1: 136,105,836	V1017G	probably damaging	Het
Chrna4	G	T	2: 181,029,442	Q174K	probably damaging	Het
Chrnb1	A	T	11: 69,786,939	V329D	probably damaging	Het
Chst14	T	C	2: 118,927,733	L336P	probably damaging	Het
Clec2e	T	C	6: 129,100,809	D22G	probably benign	Het
Csrnp2	A	C	15: 100,482,382	S343A	probably benign	Het
Dapl1	C	A	2: 59,484,713	A2E	probably damaging	Het
Dlec1	G	T	9: 119,121,923	R519L	probably damaging	Het
Dmgdh	T	A	13: 93,708,743	F415I	possibly damaging	Het
Dmgdh	T	C	13: 93,752,326	V824A	probably damaging	Het
Dnah11	T	G	12: 117,928,456	T3661P	probably benign	Het
Dnajc11	C	A	4: 151,978,126		probably benign	Het
Dot1l	A	G	10: 80,786,095	E527G	probably damaging	Het
Drc7	T	C	8: 95,075,051	L680P	probably damaging	Het
Dysf	T	C	6: 84,106,862	Y742H	probably benign	Het
Ece1	A	G	4: 137,961,647	Y665C	probably damaging	Het
Emc1	A	G	4: 139,354,222	K54E	possibly damaging	Het
Enoph1	C	T	5: 100,067,901	T247M	probably damaging	Het
Exoc2	T	C	13: 30,900,829	K383R	probably benign	Het
Fam227b	A	T	2: 126,121,052	H181Q	probably damaging	Het
Fsip2	A	T	2: 82,985,673	M3917L	probably benign	Het
Gtf3a	T	A	5: 146,955,528		probably benign	Het
Hgfac	T	A	5: 35,041,629	C11*	probably null	Het
Hmcn1	C	A	1: 150,663,909	A2944S	probably damaging	Het
Hps5	T	A	7: 46,767,097	Y947F	probably benign	Het
Ighv2-5	A	T	12: 113,685,500	I111K	probably benign	Het
Inpp5e	A	T	2: 26,407,848	L247*	probably null	Het
Kbtbd11	T	C	8: 15,027,577	S59P	probably benign	Het
Kctd19	G	A	8: 105,396,450	H111Y	probably damaging	Het
Kif1a	T	C	1: 93,024,648	D1303G	probably damaging	Het
Kif7	A	G	7: 79,714,094	V22A	possibly damaging	Het
Lrit3	A	T	3: 129,789,355	C328S	probably damaging	Het
Lrrc37a	G	T	11: 103,497,658	Q2314K	unknown	Het
Lurap1	G	T	4: 116,137,402	P211T	possibly damaging	Het
Mbd2	T	A	18: 70,580,803	N5K	possibly damaging	Het
Mbtps1	A	C	8: 119,515,602	L894V	probably benign	Het
Mefv	G	A	16: 3,708,042	S787F	possibly damaging	Het
Miip	T	A	4: 147,862,335	I289F	probably damaging	Het
Mogat2	T	A	7: 99,223,513	I155F	possibly damaging	Het
Mpp3	C	A	11: 102,011,689		probably null	Het
Mrrf	A	G	2: 36,177,221	K220E	probably damaging	Het
Mtmr6	C	T	14: 60,298,170	P485L	probably damaging	Het
Mtor	G	A	4: 148,537,435	R1896K	probably benign	Het
Myh3	C	T	11: 67,087,545	P453S	probably benign	Het
Nebl	A	G	2: 17,450,234	V112A	probably benign	Het
Nmnat2	G	A	1: 153,074,734	W55*	probably null	Het
Nprl3	A	G	11: 32,267,432	S37P	probably damaging	Het
Olfr1246	T	C	2: 89,591,101	N5D	possibly damaging	Het
Oraov1	G	T	7: 144,915,286	V17L	possibly damaging	Het
Pcdhga4	T	G	18: 37,686,330	S311A	probably benign	Het
Pcdhgb6	T	C	18: 37,743,112	V291A	probably benign	Het
Peg10	GAT	GATCAT	6: 4,756,449		probably benign	Het
Peg3	T	C	7: 6,709,571	E884G	probably damaging	Het
Pgpep1	G	A	8: 70,652,451	T53M	probably damaging	Het
Phf12	A	G	11: 78,009,515	T146A	probably benign	Het
Polr3k	C	G	2: 181,864,488	N10K	probably damaging	Het
Prickle4	C	A	17: 47,690,210	G144C	probably damaging	Het
Ptpn6	T	C	6: 124,732,435	Y25C	probably damaging	Het
Rad1	A	G	15: 10,488,074	I95V	probably damaging	Het
Rad23b	A	G	4: 55,382,540	T248A	probably benign	Het
Rapgef3	T	C	15: 97,758,861	D299G	probably damaging	Het
Rcc2	T	G	4: 140,717,024	V342G	possibly damaging	Het
Rgs3	G	T	4: 62,625,906	R136L	probably damaging	Het
Scube2	A	T	7: 109,833,013	C399*	probably null	Het
Serpinb3d	T	C	1: 107,079,722	Y178C	probably damaging	Het
Slc1a7	A	G	4: 108,012,261	T508A	probably benign	Het
Slc29a4	C	T	5: 142,720,077	R439C	probably damaging	Het
Sntg2	A	G	12: 30,312,561	I62T	probably benign	Het
Sowaha	G	A	11: 53,479,087	P274L	probably damaging	Het
Sptan1	A	G	2: 29,996,782	N869S	probably benign	Het
Stx18	C	A	5: 38,106,564	A64D	probably damaging	Het
Stxbp5	A	G	10: 9,770,686	V94A	probably benign	Het
Sult1a1	T	A	7: 126,676,452		probably null	Het
Susd1	G	T	4: 59,379,687	H313Q	possibly damaging	Het
Tdrd9	A	T	12: 111,985,041	K88N	probably damaging	Het
Tlr5	A	C	1: 182,974,038	R302S	possibly damaging	Het
Tnr	C	T	1: 159,886,909	T786I	probably damaging	Het
Tprgl	A	G	4: 154,160,095	S148P	probably damaging	Het
Trpc4ap	T	A	2: 155,671,074	N127I	probably damaging	Het
Tulp2	T	A	7: 45,490,373		probably null	Het
Uggt2	C	T	14: 119,035,969		probably null	Het
Ulk4	T	A	9: 121,272,955	Y19F	probably damaging	Het
Upf1	T	C	8: 70,333,037	Y1053C	probably damaging	Het
Vars2	A	T	17: 35,665,788	H223Q	probably benign	Het
Vmn2r106	T	A	17: 20,267,544		probably null	Het
Ythdc2	T	A	18: 44,840,210	F305I	probably damaging	Het
Zfp281	T	C	1: 136,625,440	F52S	possibly damaging	Het
Zfp292	A	T	4: 34,809,784	C1087S	probably damaging	Het
Zfp335	A	T	2: 164,895,098		probably null	Het

Other mutations in Dnah3

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00650:Dnah3	APN	7	119,938,905 (GRCm38)	missense	possibly damaging	0.88
IGL01095:Dnah3	APN	7	119,951,597 (GRCm38)	missense	probably benign	0.02
IGL01329:Dnah3	APN	7	120,022,941 (GRCm38)	missense	probably damaging	1.00
IGL01380:Dnah3	APN	7	119,926,564 (GRCm38)	missense	probably damaging	1.00
IGL01410:Dnah3	APN	7	119,967,720 (GRCm38)	missense	possibly damaging	0.91
IGL01487:Dnah3	APN	7	119,965,530 (GRCm38)	nonsense	probably null
IGL01843:Dnah3	APN	7	119,943,575 (GRCm38)	missense	probably benign	0.12
IGL01929:Dnah3	APN	7	119,951,651 (GRCm38)	nonsense	probably null
IGL01994:Dnah3	APN	7	119,951,214 (GRCm38)	missense	possibly damaging	0.58
IGL02115:Dnah3	APN	7	120,029,054 (GRCm38)	missense	probably damaging	1.00
IGL02273:Dnah3	APN	7	119,951,271 (GRCm38)	missense	probably damaging	1.00
IGL02299:Dnah3	APN	7	119,967,579 (GRCm38)	missense	probably benign	0.39
IGL02421:Dnah3	APN	7	119,950,992 (GRCm38)	missense	possibly damaging	0.87
IGL02514:Dnah3	APN	7	119,966,247 (GRCm38)	missense	probably damaging	1.00
IGL02596:Dnah3	APN	7	119,938,914 (GRCm38)	missense	probably benign	0.19
IGL02716:Dnah3	APN	7	119,937,023 (GRCm38)	missense	probably damaging	0.97
IGL02738:Dnah3	APN	7	119,965,497 (GRCm38)	missense	probably benign
IGL03404:Dnah3	APN	7	119,938,977 (GRCm38)	missense	probably damaging	1.00
R0964_Dnah3_480	UTSW	7	119,952,739 (GRCm38)	splice site	probably benign
R1778_Dnah3_238	UTSW	7	120,078,402 (GRCm38)	missense	probably damaging	1.00
R4658_Dnah3_599	UTSW	7	119,950,651 (GRCm38)	missense	probably damaging	1.00
BB004:Dnah3	UTSW	7	119,951,271 (GRCm38)	missense	probably damaging	0.97
BB014:Dnah3	UTSW	7	119,951,271 (GRCm38)	missense	probably damaging	0.97
R0011:Dnah3	UTSW	7	120,019,701 (GRCm38)	missense	probably damaging	1.00
R0195:Dnah3	UTSW	7	120,077,775 (GRCm38)	critical splice donor site	probably null
R0241:Dnah3	UTSW	7	119,922,730 (GRCm38)	missense	probably damaging	1.00
R0241:Dnah3	UTSW	7	119,922,730 (GRCm38)	missense	probably damaging	1.00
R0312:Dnah3	UTSW	7	120,045,659 (GRCm38)	missense	probably damaging	1.00
R0316:Dnah3	UTSW	7	119,965,659 (GRCm38)	missense	possibly damaging	0.94
R0370:Dnah3	UTSW	7	120,086,720 (GRCm38)	missense	possibly damaging	0.91
R0426:Dnah3	UTSW	7	119,943,572 (GRCm38)	missense	probably benign	0.11
R0525:Dnah3	UTSW	7	119,928,754 (GRCm38)	missense	probably damaging	1.00
R0625:Dnah3	UTSW	7	120,071,887 (GRCm38)	missense	possibly damaging	0.68
R0627:Dnah3	UTSW	7	120,020,915 (GRCm38)	missense	probably damaging	1.00
R0632:Dnah3	UTSW	7	119,967,905 (GRCm38)	missense	probably benign	0.11
R0928:Dnah3	UTSW	7	120,030,051 (GRCm38)	missense	probably damaging	1.00
R0964:Dnah3	UTSW	7	119,952,739 (GRCm38)	splice site	probably benign
R0972:Dnah3	UTSW	7	120,035,340 (GRCm38)	splice site	probably null
R1066:Dnah3	UTSW	7	120,061,009 (GRCm38)	missense	probably damaging	1.00
R1082:Dnah3	UTSW	7	120,078,445 (GRCm38)	missense	probably damaging	1.00
R1127:Dnah3	UTSW	7	119,923,030 (GRCm38)	missense	probably damaging	1.00
R1132:Dnah3	UTSW	7	119,939,004 (GRCm38)	missense	possibly damaging	0.50
R1222:Dnah3	UTSW	7	120,090,676 (GRCm38)	missense	probably benign	0.28
R1420:Dnah3	UTSW	7	119,951,979 (GRCm38)	missense	probably damaging	0.99
R1456:Dnah3	UTSW	7	120,047,630 (GRCm38)	missense	probably damaging	1.00
R1472:Dnah3	UTSW	7	120,070,958 (GRCm38)	missense	probably benign	0.12
R1617:Dnah3	UTSW	7	120,089,946 (GRCm38)	missense	probably benign	0.01
R1624:Dnah3	UTSW	7	120,019,695 (GRCm38)	missense	probably damaging	0.99
R1654:Dnah3	UTSW	7	119,926,449 (GRCm38)	missense	probably damaging	1.00
R1673:Dnah3	UTSW	7	119,971,179 (GRCm38)	nonsense	probably null
R1677:Dnah3	UTSW	7	119,928,740 (GRCm38)	missense	probably damaging	1.00
R1687:Dnah3	UTSW	7	120,045,786 (GRCm38)	splice site	probably null
R1711:Dnah3	UTSW	7	120,078,571 (GRCm38)	missense	probably damaging	1.00
R1738:Dnah3	UTSW	7	120,035,359 (GRCm38)	missense	probably damaging	1.00
R1778:Dnah3	UTSW	7	120,078,402 (GRCm38)	missense	probably damaging	1.00
R1866:Dnah3	UTSW	7	119,928,856 (GRCm38)	splice site	probably null
R1883:Dnah3	UTSW	7	120,077,919 (GRCm38)	missense	probably benign	0.06
R1894:Dnah3	UTSW	7	120,086,334 (GRCm38)	missense	probably benign	0.05
R1929:Dnah3	UTSW	7	119,975,129 (GRCm38)	missense	probably benign	0.10
R1988:Dnah3	UTSW	7	119,967,959 (GRCm38)	missense	probably damaging	0.99
R1988:Dnah3	UTSW	7	119,967,570 (GRCm38)	missense	possibly damaging	0.92
R2010:Dnah3	UTSW	7	120,095,177 (GRCm38)	start codon destroyed	probably benign	0.00
R2022:Dnah3	UTSW	7	119,951,242 (GRCm38)	missense	probably damaging	1.00
R2026:Dnah3	UTSW	7	120,039,406 (GRCm38)	missense	probably damaging	1.00
R2063:Dnah3	UTSW	7	119,951,909 (GRCm38)	missense	probably damaging	0.96
R2131:Dnah3	UTSW	7	119,967,759 (GRCm38)	missense	possibly damaging	0.93
R2152:Dnah3	UTSW	7	119,952,013 (GRCm38)	missense	probably benign	0.02
R2199:Dnah3	UTSW	7	119,951,569 (GRCm38)	missense	possibly damaging	0.89
R2271:Dnah3	UTSW	7	119,975,129 (GRCm38)	missense	probably benign	0.10
R2350:Dnah3	UTSW	7	120,045,788 (GRCm38)	splice site	probably null
R2567:Dnah3	UTSW	7	119,952,697 (GRCm38)	missense	possibly damaging	0.83
R2848:Dnah3	UTSW	7	119,967,938 (GRCm38)	missense	probably benign	0.01
R2902:Dnah3	UTSW	7	119,951,499 (GRCm38)	missense	possibly damaging	0.61
R2926:Dnah3	UTSW	7	119,951,115 (GRCm38)	missense	probably damaging	1.00
R2944:Dnah3	UTSW	7	119,951,110 (GRCm38)	missense	probably damaging	1.00
R3022:Dnah3	UTSW	7	120,078,481 (GRCm38)	missense	possibly damaging	0.93
R3401:Dnah3	UTSW	7	119,967,656 (GRCm38)	missense	probably benign	0.00
R3402:Dnah3	UTSW	7	119,967,656 (GRCm38)	missense	probably benign	0.00
R3403:Dnah3	UTSW	7	119,967,656 (GRCm38)	missense	probably benign	0.00
R3919:Dnah3	UTSW	7	119,951,080 (GRCm38)	missense	probably damaging	1.00
R3972:Dnah3	UTSW	7	120,086,720 (GRCm38)	missense	probably damaging	0.99
R4162:Dnah3	UTSW	7	119,922,838 (GRCm38)	missense	probably damaging	1.00
R4184:Dnah3	UTSW	7	120,083,293 (GRCm38)	missense	probably damaging	1.00
R4198:Dnah3	UTSW	7	119,922,838 (GRCm38)	missense	probably damaging	1.00
R4199:Dnah3	UTSW	7	119,922,838 (GRCm38)	missense	probably damaging	1.00
R4200:Dnah3	UTSW	7	119,922,838 (GRCm38)	missense	probably damaging	1.00
R4239:Dnah3	UTSW	7	120,029,025 (GRCm38)	nonsense	probably null
R4478:Dnah3	UTSW	7	120,071,863 (GRCm38)	missense	probably benign	0.00
R4579:Dnah3	UTSW	7	120,009,331 (GRCm38)	missense	probably damaging	1.00
R4600:Dnah3	UTSW	7	120,089,946 (GRCm38)	missense	probably benign
R4649:Dnah3	UTSW	7	120,047,698 (GRCm38)	missense	probably damaging	1.00
R4658:Dnah3	UTSW	7	119,950,651 (GRCm38)	missense	probably damaging	1.00
R4728:Dnah3	UTSW	7	120,059,366 (GRCm38)	missense	probably damaging	0.99
R4739:Dnah3	UTSW	7	120,077,946 (GRCm38)	missense	possibly damaging	0.54
R4758:Dnah3	UTSW	7	120,079,406 (GRCm38)	missense	probably benign	0.00
R4785:Dnah3	UTSW	7	119,967,824 (GRCm38)	missense	probably benign	0.29
R4789:Dnah3	UTSW	7	120,011,072 (GRCm38)	missense	probably damaging	1.00
R4930:Dnah3	UTSW	7	119,951,681 (GRCm38)	nonsense	probably null
R4935:Dnah3	UTSW	7	120,016,477 (GRCm38)	nonsense	probably null
R4946:Dnah3	UTSW	7	119,931,560 (GRCm38)	missense	probably damaging	1.00
R4981:Dnah3	UTSW	7	119,956,201 (GRCm38)	missense	probably benign	0.03
R4984:Dnah3	UTSW	7	119,928,779 (GRCm38)	missense	probably benign	0.04
R5025:Dnah3	UTSW	7	120,071,905 (GRCm38)	missense	probably benign	0.02
R5046:Dnah3	UTSW	7	119,951,580 (GRCm38)	missense	probably damaging	1.00
R5056:Dnah3	UTSW	7	120,020,946 (GRCm38)	missense	probably damaging	1.00
R5068:Dnah3	UTSW	7	120,032,790 (GRCm38)	missense	probably benign
R5069:Dnah3	UTSW	7	120,032,790 (GRCm38)	missense	probably benign
R5154:Dnah3	UTSW	7	119,952,419 (GRCm38)	missense	probably damaging	1.00
R5208:Dnah3	UTSW	7	120,032,638 (GRCm38)	missense	probably damaging	1.00
R5323:Dnah3	UTSW	7	120,021,011 (GRCm38)	missense	probably damaging	1.00
R5330:Dnah3	UTSW	7	119,943,648 (GRCm38)	missense	probably benign	0.00
R5385:Dnah3	UTSW	7	119,924,903 (GRCm38)	missense	probably damaging	1.00
R5391:Dnah3	UTSW	7	120,090,076 (GRCm38)	missense	probably benign	0.02
R5564:Dnah3	UTSW	7	119,971,466 (GRCm38)	critical splice donor site	probably null
R5594:Dnah3	UTSW	7	119,971,621 (GRCm38)	missense	possibly damaging	0.89
R5610:Dnah3	UTSW	7	119,939,065 (GRCm38)	splice site	probably null
R5673:Dnah3	UTSW	7	119,951,589 (GRCm38)	missense	possibly damaging	0.91
R5678:Dnah3	UTSW	7	120,077,851 (GRCm38)	missense	probably benign	0.00
R5737:Dnah3	UTSW	7	120,059,198 (GRCm38)	missense	probably benign	0.03
R5766:Dnah3	UTSW	7	119,978,222 (GRCm38)	missense	probably damaging	1.00
R5769:Dnah3	UTSW	7	120,089,952 (GRCm38)	nonsense	probably null
R5789:Dnah3	UTSW	7	119,943,599 (GRCm38)	missense	possibly damaging	0.70
R5791:Dnah3	UTSW	7	119,931,473 (GRCm38)	missense	probably benign	0.00
R5841:Dnah3	UTSW	7	119,951,021 (GRCm38)	utr 3 prime	probably benign
R5843:Dnah3	UTSW	7	119,951,021 (GRCm38)	utr 3 prime	probably benign
R5844:Dnah3	UTSW	7	119,951,021 (GRCm38)	utr 3 prime	probably benign
R5846:Dnah3	UTSW	7	119,951,021 (GRCm38)	utr 3 prime	probably benign
R5851:Dnah3	UTSW	7	120,039,362 (GRCm38)	missense	possibly damaging	0.51
R5853:Dnah3	UTSW	7	119,938,833 (GRCm38)	missense	probably damaging	1.00
R5857:Dnah3	UTSW	7	119,951,021 (GRCm38)	utr 3 prime	probably benign
R5865:Dnah3	UTSW	7	119,975,108 (GRCm38)	missense	probably benign	0.00
R5885:Dnah3	UTSW	7	120,069,704 (GRCm38)	missense	probably benign	0.10
R5898:Dnah3	UTSW	7	120,078,501 (GRCm38)	missense	probably benign	0.37
R5917:Dnah3	UTSW	7	120,016,526 (GRCm38)	missense	probably damaging	1.00
R5964:Dnah3	UTSW	7	119,922,880 (GRCm38)	missense	probably benign	0.00
R5990:Dnah3	UTSW	7	120,073,541 (GRCm38)	missense	probably benign
R6004:Dnah3	UTSW	7	120,086,297 (GRCm38)	missense	probably benign	0.10
R6033:Dnah3	UTSW	7	120,071,647 (GRCm38)	missense	probably benign	0.00
R6033:Dnah3	UTSW	7	120,071,647 (GRCm38)	missense	probably benign	0.00
R6045:Dnah3	UTSW	7	119,967,522 (GRCm38)	missense	probably damaging	0.99
R6133:Dnah3	UTSW	7	120,086,246 (GRCm38)	missense	probably benign	0.10
R6229:Dnah3	UTSW	7	119,965,488 (GRCm38)	missense	probably benign	0.11
R6237:Dnah3	UTSW	7	120,009,384 (GRCm38)	missense	probably damaging	1.00
R6333:Dnah3	UTSW	7	120,054,633 (GRCm38)	missense	probably damaging	1.00
R6408:Dnah3	UTSW	7	119,922,968 (GRCm38)	splice site	probably null
R6447:Dnah3	UTSW	7	119,923,054 (GRCm38)	missense	probably benign	0.12
R6606:Dnah3	UTSW	7	120,060,956 (GRCm38)	missense	probably benign	0.02
R6666:Dnah3	UTSW	7	120,070,949 (GRCm38)	missense	probably benign	0.16
R6733:Dnah3	UTSW	7	119,922,974 (GRCm38)	missense	probably benign	0.22
R6815:Dnah3	UTSW	7	119,971,727 (GRCm38)	missense	probably benign
R6882:Dnah3	UTSW	7	119,971,184 (GRCm38)	missense	possibly damaging	0.95
R6934:Dnah3	UTSW	7	120,054,601 (GRCm38)	critical splice donor site	probably null
R6966:Dnah3	UTSW	7	120,032,754 (GRCm38)	missense	probably damaging	1.00
R7025:Dnah3	UTSW	7	120,030,010 (GRCm38)	missense	possibly damaging	0.90
R7207:Dnah3	UTSW	7	119,971,089 (GRCm38)	missense	probably damaging	1.00
R7214:Dnah3	UTSW	7	119,922,742 (GRCm38)	missense	probably damaging	1.00
R7222:Dnah3	UTSW	7	120,071,523 (GRCm38)	missense	probably benign	0.00
R7235:Dnah3	UTSW	7	120,032,670 (GRCm38)	missense	probably damaging	1.00
R7241:Dnah3	UTSW	7	119,943,633 (GRCm38)	missense	probably benign	0.03
R7313:Dnah3	UTSW	7	119,981,344 (GRCm38)	missense	probably benign	0.39
R7342:Dnah3	UTSW	7	120,029,985 (GRCm38)	missense	probably damaging	1.00
R7368:Dnah3	UTSW	7	120,029,016 (GRCm38)	missense	probably benign
R7375:Dnah3	UTSW	7	119,951,677 (GRCm38)	missense	probably damaging	1.00
R7395:Dnah3	UTSW	7	120,060,960 (GRCm38)	missense	probably benign	0.00
R7395:Dnah3	UTSW	7	119,966,251 (GRCm38)	missense
R7431:Dnah3	UTSW	7	120,051,744 (GRCm38)	missense	probably damaging	1.00
R7499:Dnah3	UTSW	7	120,060,912 (GRCm38)	missense	probably damaging	0.99
R7515:Dnah3	UTSW	7	120,073,592 (GRCm38)	missense	probably benign	0.21
R7564:Dnah3	UTSW	7	119,971,594 (GRCm38)	missense	probably benign
R7618:Dnah3	UTSW	7	119,978,378 (GRCm38)	missense	probably damaging	0.97
R7697:Dnah3	UTSW	7	119,967,434 (GRCm38)	missense
R7728:Dnah3	UTSW	7	119,938,828 (GRCm38)	missense	probably damaging	1.00
R7757:Dnah3	UTSW	7	119,971,215 (GRCm38)	splice site	probably null
R7757:Dnah3	UTSW	7	120,071,570 (GRCm38)	missense	probably benign
R7774:Dnah3	UTSW	7	119,951,752 (GRCm38)	nonsense	probably null
R7804:Dnah3	UTSW	7	120,011,012 (GRCm38)	missense	probably damaging	1.00
R7804:Dnah3	UTSW	7	119,952,618 (GRCm38)	missense	probably damaging	1.00
R7857:Dnah3	UTSW	7	119,951,704 (GRCm38)	missense	probably damaging	1.00
R7871:Dnah3	UTSW	7	119,967,552 (GRCm38)	missense
R7903:Dnah3	UTSW	7	120,042,128 (GRCm38)	missense	probably damaging	1.00
R7927:Dnah3	UTSW	7	119,951,271 (GRCm38)	missense	probably damaging	0.97
R7989:Dnah3	UTSW	7	120,077,789 (GRCm38)	missense	probably benign
R8142:Dnah3	UTSW	7	120,060,966 (GRCm38)	missense	probably benign	0.00
R8164:Dnah3	UTSW	7	119,967,614 (GRCm38)	missense	probably damaging	1.00
R8237:Dnah3	UTSW	7	119,926,413 (GRCm38)	missense	probably benign	0.01
R8313:Dnah3	UTSW	7	119,951,152 (GRCm38)	missense	probably benign	0.38
R8338:Dnah3	UTSW	7	120,071,881 (GRCm38)	missense	probably benign	0.01
R8355:Dnah3	UTSW	7	119,952,208 (GRCm38)	missense	probably damaging	1.00
R8408:Dnah3	UTSW	7	119,952,505 (GRCm38)	missense	probably damaging	1.00
R8411:Dnah3	UTSW	7	120,011,030 (GRCm38)	missense	probably damaging	1.00
R8455:Dnah3	UTSW	7	119,952,208 (GRCm38)	missense	probably damaging	1.00
R8483:Dnah3	UTSW	7	119,937,030 (GRCm38)	missense	probably benign	0.00
R8531:Dnah3	UTSW	7	119,951,368 (GRCm38)	missense	probably damaging	1.00
R8885:Dnah3	UTSW	7	119,962,152 (GRCm38)	missense
R8912:Dnah3	UTSW	7	120,090,646 (GRCm38)	missense	probably benign	0.06
R8966:Dnah3	UTSW	7	119,950,658 (GRCm38)	nonsense	probably null
R8982:Dnah3	UTSW	7	119,937,071 (GRCm38)	missense	probably damaging	1.00
R9043:Dnah3	UTSW	7	119,952,049 (GRCm38)	missense	probably benign
R9053:Dnah3	UTSW	7	120,019,764 (GRCm38)	missense	possibly damaging	0.67
R9059:Dnah3	UTSW	7	120,085,145 (GRCm38)	missense	probably benign	0.01
R9182:Dnah3	UTSW	7	120,085,128 (GRCm38)	missense	probably damaging	0.98
R9365:Dnah3	UTSW	7	119,967,636 (GRCm38)	missense
R9383:Dnah3	UTSW	7	120,047,596 (GRCm38)	missense	probably benign	0.23
R9430:Dnah3	UTSW	7	120,028,982 (GRCm38)	missense	probably damaging	1.00
R9449:Dnah3	UTSW	7	119,952,250 (GRCm38)	missense	probably benign	0.12
R9462:Dnah3	UTSW	7	119,952,300 (GRCm38)	missense	probably benign	0.05
R9505:Dnah3	UTSW	7	120,045,689 (GRCm38)	missense	probably damaging	1.00
R9559:Dnah3	UTSW	7	120,051,728 (GRCm38)	missense	probably benign	0.07
R9562:Dnah3	UTSW	7	120,010,891 (GRCm38)	missense	probably benign	0.05
R9565:Dnah3	UTSW	7	120,010,891 (GRCm38)	missense	probably benign	0.05
R9609:Dnah3	UTSW	7	120,071,013 (GRCm38)	missense	probably damaging	0.98
R9622:Dnah3	UTSW	7	119,962,133 (GRCm38)	missense
R9633:Dnah3	UTSW	7	119,950,993 (GRCm38)	missense	probably benign
R9654:Dnah3	UTSW	7	120,042,173 (GRCm38)	nonsense	probably null
R9665:Dnah3	UTSW	7	120,045,758 (GRCm38)	missense	probably benign	0.01
R9681:Dnah3	UTSW	7	120,078,388 (GRCm38)	missense	probably benign	0.04
R9717:Dnah3	UTSW	7	119,975,076 (GRCm38)	missense	probably damaging	1.00
Z1088:Dnah3	UTSW	7	120,010,873 (GRCm38)	missense	probably null	1.00
Z1088:Dnah3	UTSW	7	120,086,297 (GRCm38)	missense	probably benign	0.00
Z1176:Dnah3	UTSW	7	119,967,803 (GRCm38)	missense
Z1177:Dnah3	UTSW	7	120,007,862 (GRCm38)	missense	probably benign
Z1177:Dnah3	UTSW	7	119,967,901 (GRCm38)	missense	probably damaging	0.99

Predicted Primers

PCR Primer
(F):5'- CTTGCAAGGGCTATACAGAAGAC -3'
(R):5'- GTATGGAAGTCAGCCCACAC -3'

Posted On

2017-07-14