Incidental Mutation 'R6102:Dsc2'
| ID |
485343 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Dsc2
|
| Ensembl Gene |
ENSMUSG00000024331 |
| Gene Name |
desmocollin 2 |
| Synonyms |
Dsc2b, Dsc2a |
| MMRRC Submission |
044252-MU
|
| Accession Numbers |
|
| Essential gene? |
Non essential
(E-score: 0.000)
|
| Stock # |
R6102 (G1)
|
| Quality Score |
225.009 |
|
Status
|
Validated
|
| Chromosome |
18 |
| Chromosomal Location |
20030633-20059554 bp(-) (GRCm38) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
T to A
at 20047108 bp (GRCm38)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Tyrosine to Phenylalanine
at position 196
(Y196F)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000074702
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000039247]
[ENSMUST00000075214]
[ENSMUST00000128464]
|
| AlphaFold |
P55292 |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000039247
AA Change: Y196F
PolyPhen 2
Score 0.013 (Sensitivity: 0.96; Specificity: 0.78)
|
| SMART Domains |
Protein: ENSMUSP00000042905
Gene: ENSMUSG00000024331
AA Change: Y196F
| Domain | Start | End | E-Value | Type |
|---|
|
Cadherin_pro
|
31 |
113 |
2.82e-37 |
SMART |
|
CA
|
156 |
241 |
4.66e-11 |
SMART |
|
CA
|
265 |
353 |
1.87e-24 |
SMART |
|
low complexity region
|
358 |
372 |
N/A |
INTRINSIC |
|
CA
|
376 |
470 |
1.27e-12 |
SMART |
|
CA
|
493 |
575 |
4.14e-17 |
SMART |
|
CA
|
594 |
676 |
1.49e-1 |
SMART |
|
transmembrane domain
|
696 |
718 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000075214
AA Change: Y196F
PolyPhen 2
Score 0.013 (Sensitivity: 0.96; Specificity: 0.78)
|
| SMART Domains |
Protein: ENSMUSP00000074702
Gene: ENSMUSG00000024331
AA Change: Y196F
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
28 |
N/A |
INTRINSIC |
|
Cadherin_pro
|
31 |
113 |
2.82e-37 |
SMART |
|
CA
|
156 |
241 |
4.66e-11 |
SMART |
|
CA
|
265 |
353 |
1.87e-24 |
SMART |
|
low complexity region
|
358 |
372 |
N/A |
INTRINSIC |
|
CA
|
376 |
470 |
1.27e-12 |
SMART |
|
CA
|
493 |
575 |
4.14e-17 |
SMART |
|
CA
|
594 |
676 |
1.49e-1 |
SMART |
|
transmembrane domain
|
696 |
718 |
N/A |
INTRINSIC |
|
Pfam:Cadherin_C
|
730 |
901 |
3.7e-9 |
PFAM |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000128464
|
| SMART Domains |
Protein: ENSMUSP00000123010
Gene: ENSMUSG00000024331
| Domain | Start | End | E-Value | Type |
|---|
|
Cadherin_pro
|
31 |
113 |
2.82e-37 |
SMART |
|
| Meta Mutation Damage Score |
0.0917 |
| Coding Region Coverage |
- 1x: 99.9%
- 3x: 99.6%
- 10x: 98.4%
- 20x: 95.6%
|
| Validation Efficiency |
97% (65/67) |
| MGI Phenotype |
FUNCTION: This gene encodes a member of the desmocollin protein subfamily. Desmocollins are cadherin-like transmembrane glycoproteins that are major components of the desmosome. Desmosomes are cell-cell junctions that help resist shearing forces and are found in high concentrations in cells subject to mechanical stress. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2015]
|
| Allele List at MGI |
All alleles(2) : Targeted, other(2) |
| Other mutations in this stock |
Total: 67 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Alox12e |
A |
G |
11: 70,320,023 (GRCm38) |
I290T |
possibly damaging |
Het |
| Apeh |
T |
A |
9: 108,086,439 (GRCm38) |
D559V |
probably damaging |
Het |
| Aspm |
T |
A |
1: 139,477,459 (GRCm38) |
Y1361* |
probably null |
Het |
| Atad5 |
G |
T |
11: 80,111,572 (GRCm38) |
|
probably null |
Het |
| Ccr4 |
C |
T |
9: 114,496,493 (GRCm38) |
|
probably null |
Het |
| Clasrp |
G |
A |
7: 19,586,468 (GRCm38) |
|
probably benign |
Het |
| Cldn23 |
A |
G |
8: 35,825,551 (GRCm38) |
M261T |
probably benign |
Het |
| Cmya5 |
T |
C |
13: 93,094,231 (GRCm38) |
M1450V |
probably benign |
Het |
| Cyp4v3 |
T |
A |
8: 45,320,160 (GRCm38) |
E202V |
probably damaging |
Het |
| Dnah7a |
A |
T |
1: 53,559,140 (GRCm38) |
V1412E |
probably benign |
Het |
| Dnah9 |
A |
G |
11: 65,990,516 (GRCm38) |
S2578P |
probably damaging |
Het |
| Exoc1 |
T |
C |
5: 76,537,779 (GRCm38) |
S113P |
probably damaging |
Het |
| Fbxo6 |
A |
T |
4: 148,149,522 (GRCm38) |
I39N |
probably damaging |
Het |
| Frs3 |
C |
T |
17: 47,702,671 (GRCm38) |
H173Y |
probably damaging |
Het |
| Ginm1 |
G |
T |
10: 7,768,496 (GRCm38) |
T323K |
probably benign |
Het |
| Golgb1 |
T |
C |
16: 36,912,865 (GRCm38) |
S825P |
probably damaging |
Het |
| Hs3st3b1 |
A |
T |
11: 63,921,855 (GRCm38) |
C11* |
probably null |
Het |
| Ighv3-3 |
G |
C |
12: 114,196,460 (GRCm38) |
A110G |
possibly damaging |
Het |
| Igkv6-20 |
G |
A |
6: 70,335,869 (GRCm38) |
H107Y |
probably benign |
Het |
| Kcnj16 |
A |
G |
11: 111,025,577 (GRCm38) |
E355G |
probably benign |
Het |
| Lig4 |
C |
T |
8: 9,972,872 (GRCm38) |
G303S |
probably damaging |
Het |
| Map1b |
A |
C |
13: 99,425,873 (GRCm38) |
V2443G |
unknown |
Het |
| Map3k6 |
T |
C |
4: 133,247,131 (GRCm38) |
|
probably null |
Het |
| Mmp13 |
A |
G |
9: 7,276,688 (GRCm38) |
Q261R |
probably benign |
Het |
| Mphosph9 |
T |
A |
5: 124,297,709 (GRCm38) |
I554F |
possibly damaging |
Het |
| Mrgpra3 |
A |
T |
7: 47,590,149 (GRCm38) |
F10I |
possibly damaging |
Het |
| Ms4a18 |
G |
A |
19: 11,013,523 (GRCm38) |
T69I |
probably benign |
Het |
| Mtmr3 |
T |
C |
11: 4,487,673 (GRCm38) |
N927S |
probably damaging |
Het |
| Necab1 |
T |
A |
4: 14,989,211 (GRCm38) |
Q188L |
probably benign |
Het |
| Nfatc2 |
A |
G |
2: 168,519,507 (GRCm38) |
|
probably benign |
Het |
| Or5i1 |
T |
C |
2: 87,782,848 (GRCm38) |
F103L |
probably damaging |
Het |
| Or5p70 |
T |
C |
7: 108,395,284 (GRCm38) |
S55P |
probably damaging |
Het |
| Or7g34 |
T |
C |
9: 19,567,022 (GRCm38) |
M121V |
possibly damaging |
Het |
| Paip2b |
A |
C |
6: 83,808,846 (GRCm38) |
V134G |
possibly damaging |
Het |
| Pax3 |
T |
C |
1: 78,132,347 (GRCm38) |
T225A |
probably damaging |
Het |
| Pbx1 |
C |
A |
1: 168,183,565 (GRCm38) |
A298S |
probably benign |
Het |
| Pcdhac2 |
A |
T |
18: 37,146,282 (GRCm38) |
K772* |
probably null |
Het |
| Pcsk4 |
A |
T |
10: 80,325,817 (GRCm38) |
Y163* |
probably null |
Het |
| Plcd3 |
A |
G |
11: 103,080,644 (GRCm38) |
V58A |
probably damaging |
Het |
| Plek2 |
T |
A |
12: 78,900,093 (GRCm38) |
T57S |
possibly damaging |
Het |
| Plscr2 |
C |
T |
9: 92,287,668 (GRCm38) |
T57I |
probably benign |
Het |
| Ppp2r5b |
A |
G |
19: 6,234,738 (GRCm38) |
S32P |
probably benign |
Het |
| Ppp3r2 |
C |
T |
4: 49,682,022 (GRCm38) |
|
probably benign |
Het |
| Psme4 |
T |
A |
11: 30,865,567 (GRCm38) |
L1693H |
probably damaging |
Het |
| Rrbp1 |
T |
A |
2: 143,988,393 (GRCm38) |
Q618L |
probably damaging |
Het |
| Rsf1 |
ATGGCG |
ATGGCGACGGTGGCG |
7: 97,579,904 (GRCm38) |
|
probably benign |
Het |
| Rsrc1 |
C |
T |
3: 66,994,649 (GRCm38) |
P44L |
unknown |
Het |
| Serpina3b |
A |
T |
12: 104,134,169 (GRCm38) |
T337S |
probably benign |
Het |
| Slc18a2 |
T |
C |
19: 59,293,878 (GRCm38) |
Y506H |
probably benign |
Het |
| Slc9a9 |
A |
G |
9: 94,936,429 (GRCm38) |
Y292C |
probably benign |
Het |
| Spta1 |
T |
C |
1: 174,224,520 (GRCm38) |
V1840A |
probably benign |
Het |
| Ssb |
T |
C |
2: 69,871,208 (GRCm38) |
*416Q |
probably null |
Het |
| Strada |
A |
G |
11: 106,168,436 (GRCm38) |
V209A |
probably benign |
Het |
| Tbc1d31 |
A |
T |
15: 57,936,093 (GRCm38) |
D225V |
probably damaging |
Het |
| Tgm4 |
T |
C |
9: 123,056,535 (GRCm38) |
F381L |
probably benign |
Het |
| Tmem120b |
T |
A |
5: 123,115,144 (GRCm38) |
Y203N |
probably damaging |
Het |
| Tmem176b |
A |
G |
6: 48,835,934 (GRCm38) |
V109A |
probably benign |
Het |
| Tnfrsf11a |
C |
A |
1: 105,819,946 (GRCm38) |
L201M |
possibly damaging |
Het |
| Ttn |
C |
A |
2: 76,974,350 (GRCm38) |
|
probably null |
Het |
| Tubb2a |
T |
C |
13: 34,075,343 (GRCm38) |
I155V |
probably benign |
Het |
| Vmn1r5 |
A |
G |
6: 56,986,114 (GRCm38) |
D258G |
probably damaging |
Het |
| Vmn2r121 |
T |
C |
X: 124,133,575 (GRCm38) |
T120A |
probably benign |
Het |
| Vmn2r19 |
A |
T |
6: 123,329,948 (GRCm38) |
I472F |
probably damaging |
Het |
| Vwa3a |
A |
G |
7: 120,776,138 (GRCm38) |
|
probably null |
Het |
| Zfp273 |
A |
G |
13: 67,822,347 (GRCm38) |
Y5C |
probably damaging |
Het |
| Zfp647 |
G |
A |
15: 76,912,085 (GRCm38) |
P125L |
probably damaging |
Het |
| Zfp825 |
A |
G |
13: 74,480,653 (GRCm38) |
L248P |
probably damaging |
Het |
|
| Other mutations in Dsc2 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00802:Dsc2
|
APN |
18 |
20,041,797 (GRCm38) |
missense |
probably benign |
0.01 |
|
IGL00826:Dsc2
|
APN |
18 |
20,035,315 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL00852:Dsc2
|
APN |
18 |
20,034,683 (GRCm38) |
missense |
probably benign |
0.01 |
|
IGL01082:Dsc2
|
APN |
18 |
20,043,792 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL01328:Dsc2
|
APN |
18 |
20,048,286 (GRCm38) |
missense |
probably damaging |
0.98 |
|
IGL01338:Dsc2
|
APN |
18 |
20,047,157 (GRCm38) |
missense |
probably benign |
0.19 |
|
IGL01727:Dsc2
|
APN |
18 |
20,038,200 (GRCm38) |
missense |
probably benign |
0.01 |
|
IGL01766:Dsc2
|
APN |
18 |
20,046,342 (GRCm38) |
missense |
possibly damaging |
0.56 |
|
IGL02228:Dsc2
|
APN |
18 |
20,043,733 (GRCm38) |
missense |
probably damaging |
0.99 |
|
IGL02560:Dsc2
|
APN |
18 |
20,045,539 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL02794:Dsc2
|
APN |
18 |
20,041,731 (GRCm38) |
missense |
probably damaging |
1.00 |
|
3-1:Dsc2
|
UTSW |
18 |
20,047,079 (GRCm38) |
missense |
possibly damaging |
0.60 |
|
PIT4305001:Dsc2
|
UTSW |
18 |
20,046,243 (GRCm38) |
missense |
probably damaging |
0.96 |
|
PIT4431001:Dsc2
|
UTSW |
18 |
20,046,277 (GRCm38) |
nonsense |
probably null |
|
|
R0288:Dsc2
|
UTSW |
18 |
20,033,120 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R0542:Dsc2
|
UTSW |
18 |
20,051,226 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R0562:Dsc2
|
UTSW |
18 |
20,041,537 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R0697:Dsc2
|
UTSW |
18 |
20,041,452 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R0940:Dsc2
|
UTSW |
18 |
20,050,059 (GRCm38) |
missense |
probably damaging |
0.97 |
|
R1081:Dsc2
|
UTSW |
18 |
20,033,295 (GRCm38) |
missense |
probably damaging |
0.96 |
|
R1140:Dsc2
|
UTSW |
18 |
20,032,212 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R1515:Dsc2
|
UTSW |
18 |
20,045,565 (GRCm38) |
missense |
probably benign |
0.40 |
|
R1515:Dsc2
|
UTSW |
18 |
20,034,701 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R1558:Dsc2
|
UTSW |
18 |
20,050,151 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R1654:Dsc2
|
UTSW |
18 |
20,046,246 (GRCm38) |
missense |
probably benign |
0.01 |
|
R2061:Dsc2
|
UTSW |
18 |
20,032,399 (GRCm38) |
missense |
possibly damaging |
0.79 |
|
R2089:Dsc2
|
UTSW |
18 |
20,033,294 (GRCm38) |
missense |
possibly damaging |
0.65 |
|
R2091:Dsc2
|
UTSW |
18 |
20,033,294 (GRCm38) |
missense |
possibly damaging |
0.65 |
|
R2091:Dsc2
|
UTSW |
18 |
20,033,294 (GRCm38) |
missense |
possibly damaging |
0.65 |
|
R2172:Dsc2
|
UTSW |
18 |
20,045,502 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R2247:Dsc2
|
UTSW |
18 |
20,035,312 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R2472:Dsc2
|
UTSW |
18 |
20,045,469 (GRCm38) |
missense |
probably benign |
0.00 |
|
R2927:Dsc2
|
UTSW |
18 |
20,045,501 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R3611:Dsc2
|
UTSW |
18 |
20,032,351 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R3961:Dsc2
|
UTSW |
18 |
20,051,227 (GRCm38) |
missense |
probably damaging |
0.98 |
|
R3963:Dsc2
|
UTSW |
18 |
20,051,227 (GRCm38) |
missense |
probably damaging |
0.98 |
|
R4353:Dsc2
|
UTSW |
18 |
20,050,068 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4362:Dsc2
|
UTSW |
18 |
20,050,157 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4612:Dsc2
|
UTSW |
18 |
20,041,819 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4613:Dsc2
|
UTSW |
18 |
20,041,819 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4752:Dsc2
|
UTSW |
18 |
20,038,222 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4946:Dsc2
|
UTSW |
18 |
20,050,157 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R5056:Dsc2
|
UTSW |
18 |
20,050,142 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R5267:Dsc2
|
UTSW |
18 |
20,034,583 (GRCm38) |
critical splice donor site |
probably null |
|
|
R5445:Dsc2
|
UTSW |
18 |
20,035,303 (GRCm38) |
missense |
possibly damaging |
0.76 |
|
R5507:Dsc2
|
UTSW |
18 |
20,046,279 (GRCm38) |
missense |
probably damaging |
0.96 |
|
R5575:Dsc2
|
UTSW |
18 |
20,035,390 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R5781:Dsc2
|
UTSW |
18 |
20,032,510 (GRCm38) |
missense |
probably benign |
0.00 |
|
R6129:Dsc2
|
UTSW |
18 |
20,045,430 (GRCm38) |
missense |
possibly damaging |
0.95 |
|
R6362:Dsc2
|
UTSW |
18 |
20,035,463 (GRCm38) |
nonsense |
probably null |
|
|
R6433:Dsc2
|
UTSW |
18 |
20,051,175 (GRCm38) |
critical splice donor site |
probably null |
|
|
R6513:Dsc2
|
UTSW |
18 |
20,046,238 (GRCm38) |
missense |
probably benign |
|
|
R6615:Dsc2
|
UTSW |
18 |
20,032,519 (GRCm38) |
missense |
possibly damaging |
0.88 |
|
R6619:Dsc2
|
UTSW |
18 |
20,032,278 (GRCm38) |
missense |
probably benign |
0.22 |
|
R6665:Dsc2
|
UTSW |
18 |
20,050,148 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R6961:Dsc2
|
UTSW |
18 |
20,038,222 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R7179:Dsc2
|
UTSW |
18 |
20,035,275 (GRCm38) |
critical splice donor site |
probably null |
|
|
R7275:Dsc2
|
UTSW |
18 |
20,051,179 (GRCm38) |
nonsense |
probably null |
|
|
R7352:Dsc2
|
UTSW |
18 |
20,035,335 (GRCm38) |
missense |
probably benign |
0.39 |
|
R7386:Dsc2
|
UTSW |
18 |
20,041,926 (GRCm38) |
missense |
possibly damaging |
0.84 |
|
R7496:Dsc2
|
UTSW |
18 |
20,035,394 (GRCm38) |
nonsense |
probably null |
|
|
R7510:Dsc2
|
UTSW |
18 |
20,032,274 (GRCm38) |
missense |
possibly damaging |
0.78 |
|
R7580:Dsc2
|
UTSW |
18 |
20,050,073 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R7718:Dsc2
|
UTSW |
18 |
20,041,778 (GRCm38) |
missense |
probably damaging |
0.98 |
|
R7733:Dsc2
|
UTSW |
18 |
20,048,316 (GRCm38) |
missense |
probably benign |
0.16 |
|
R7733:Dsc2
|
UTSW |
18 |
20,048,315 (GRCm38) |
missense |
probably benign |
0.00 |
|
R7818:Dsc2
|
UTSW |
18 |
20,050,132 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R7852:Dsc2
|
UTSW |
18 |
20,046,285 (GRCm38) |
missense |
possibly damaging |
0.67 |
|
R7998:Dsc2
|
UTSW |
18 |
20,034,663 (GRCm38) |
missense |
possibly damaging |
0.87 |
|
R8029:Dsc2
|
UTSW |
18 |
20,032,274 (GRCm38) |
missense |
possibly damaging |
0.78 |
|
R8030:Dsc2
|
UTSW |
18 |
20,032,274 (GRCm38) |
missense |
possibly damaging |
0.78 |
|
R8031:Dsc2
|
UTSW |
18 |
20,032,274 (GRCm38) |
missense |
possibly damaging |
0.78 |
|
R8032:Dsc2
|
UTSW |
18 |
20,032,274 (GRCm38) |
missense |
possibly damaging |
0.78 |
|
R8059:Dsc2
|
UTSW |
18 |
20,032,274 (GRCm38) |
missense |
possibly damaging |
0.78 |
|
R8060:Dsc2
|
UTSW |
18 |
20,032,274 (GRCm38) |
missense |
possibly damaging |
0.78 |
|
R8061:Dsc2
|
UTSW |
18 |
20,032,274 (GRCm38) |
missense |
possibly damaging |
0.78 |
|
R8062:Dsc2
|
UTSW |
18 |
20,032,274 (GRCm38) |
missense |
possibly damaging |
0.78 |
|
R8063:Dsc2
|
UTSW |
18 |
20,032,274 (GRCm38) |
missense |
possibly damaging |
0.78 |
|
R8082:Dsc2
|
UTSW |
18 |
20,032,274 (GRCm38) |
missense |
possibly damaging |
0.78 |
|
R8090:Dsc2
|
UTSW |
18 |
20,032,274 (GRCm38) |
missense |
possibly damaging |
0.78 |
|
R8114:Dsc2
|
UTSW |
18 |
20,032,274 (GRCm38) |
missense |
possibly damaging |
0.78 |
|
R8115:Dsc2
|
UTSW |
18 |
20,032,274 (GRCm38) |
missense |
possibly damaging |
0.78 |
|
R8116:Dsc2
|
UTSW |
18 |
20,032,274 (GRCm38) |
missense |
possibly damaging |
0.78 |
|
R8117:Dsc2
|
UTSW |
18 |
20,032,274 (GRCm38) |
missense |
possibly damaging |
0.78 |
|
R8118:Dsc2
|
UTSW |
18 |
20,032,274 (GRCm38) |
missense |
possibly damaging |
0.78 |
|
R8328:Dsc2
|
UTSW |
18 |
20,032,519 (GRCm38) |
missense |
possibly damaging |
0.68 |
|
R8545:Dsc2
|
UTSW |
18 |
20,034,665 (GRCm38) |
nonsense |
probably null |
|
|
R9005:Dsc2
|
UTSW |
18 |
20,038,094 (GRCm38) |
missense |
probably benign |
0.00 |
|
R9017:Dsc2
|
UTSW |
18 |
20,043,911 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R9111:Dsc2
|
UTSW |
18 |
20,034,707 (GRCm38) |
missense |
probably benign |
0.00 |
|
R9396:Dsc2
|
UTSW |
18 |
20,041,716 (GRCm38) |
nonsense |
probably null |
|
|
R9487:Dsc2
|
UTSW |
18 |
20,047,219 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R9663:Dsc2
|
UTSW |
18 |
20,038,148 (GRCm38) |
missense |
probably damaging |
1.00 |
|
Z1088:Dsc2
|
UTSW |
18 |
20,046,304 (GRCm38) |
missense |
probably damaging |
0.98 |
|
Z1176:Dsc2
|
UTSW |
18 |
20,035,299 (GRCm38) |
missense |
probably damaging |
1.00 |
|
| Predicted Primers |
PCR Primer
(F):5'- GATATAGTGACTGAAGTTAATAACCGC -3'
(R):5'- TCTGAAAACTGAATGCAACAGG -3'
Sequencing Primer
(F):5'- CCTTTGTAAGTGGAACAATCCCTGG -3'
(R):5'- ATTTTAGTAACTGGCAGTGAGATTG -3'
|
| Posted On |
2017-08-16 |
Incidental Mutation