Mutagenetix > Incidental Mutation

Incidental Mutation 'R6091:Fcgbp'

485921

Institutional Source

Beutler Lab

Gene Symbol

Fcgbp

Ensembl Gene

ENSMUSG00000047730

Gene Name

Fc fragment of IgG binding protein

Synonyms

A430096B05Rik

MMRRC Submission

044248-MU

Accession Numbers

Essential gene?

Non essential (E-score: 0.000) question?

Stock #

R6091 (G1)

Quality Score

225.009

Status

Validated

Chromosome

Chromosomal Location

27770661-27820287 bp(+) (GRCm39)

Type of Mutation

missense

DNA Base Change (assembly)

A to G at 27804390 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Threonine to Alanine at position 1833 (T1833A)

Ref Sequence

ENSEMBL: ENSMUSP00000114271 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000076648] [ENSMUST00000138392]

AlphaFold

E9Q0B5

Predicted Effect

possibly damaging
Transcript: ENSMUST00000076648
AA Change: T1833A

PolyPhen 2 Score 0.691 (Sensitivity: 0.86; Specificity: 0.92)

SMART Domains

Protein: ENSMUSP00000075945
Gene: ENSMUSG00000047730
AA Change: T1833A

Domain	Start	End	E-Value	Type
signal peptide	1	26	N/A	INTRINSIC
FOLN	27	49	2.3e-4	SMART
VWD	46	211	5.26e-45	SMART
low complexity region	226	237	N/A	INTRINSIC
C8	251	326	1.17e-34	SMART
Pfam:TIL	329	383	1.2e-12	PFAM
VWC	385	431	2.34e-1	SMART
FOLN	418	441	3.48e1	SMART
VWD	438	603	6.85e-35	SMART
C8	642	717	1.4e-32	SMART
Pfam:TIL	720	773	4.7e-14	PFAM
VWC	775	829	9.42e-1	SMART
VWD	824	990	7.86e-44	SMART
C8	1034	1109	1.66e-34	SMART
Pfam:TIL	1112	1165	6.7e-13	PFAM
VWC	1167	1225	9.8e-3	SMART
FOLN	1198	1220	9.55e-1	SMART
FOLN	1224	1246	2.41e0	SMART
VWD	1243	1411	6.59e-37	SMART
C8	1451	1527	5.6e-32	SMART
low complexity region	1541	1551	N/A	INTRINSIC
EGF_like	1558	1581	6.15e1	SMART
VWC	1589	1682	1.6e-2	SMART
VWD	1640	1807	5.15e-39	SMART
C8	1839	1914	4.62e-33	SMART
EGF_like	1942	1965	4.46e1	SMART
VWC	1972	2064	1.92e-1	SMART
VWD	2024	2180	6.34e-39	SMART
low complexity region	2201	2214	N/A	INTRINSIC
C8	2221	2296	3.7e-32	SMART
Pfam:TIL	2299	2352	5e-12	PFAM
VWC	2354	2413	8.29e-1	SMART
FOLN	2385	2407	4.96e1	SMART
VWD	2404	2566	1.89e-5	SMART

Predicted Effect

possibly damaging
Transcript: ENSMUST00000138392
AA Change: T1833A

PolyPhen 2 Score 0.899 (Sensitivity: 0.82; Specificity: 0.94)

SMART Domains

Protein: ENSMUSP00000114271
Gene: ENSMUSG00000047730
AA Change: T1833A

Domain	Start	End	E-Value	Type
signal peptide	1	26	N/A	INTRINSIC
FOLN	27	49	2.3e-4	SMART
VWD	46	211	5.26e-45	SMART
low complexity region	226	237	N/A	INTRINSIC
C8	251	326	1.17e-34	SMART
Pfam:TIL	329	383	8.4e-13	PFAM
VWC	385	431	2.34e-1	SMART
FOLN	418	441	3.48e1	SMART
VWD	438	603	7.99e-36	SMART
C8	642	717	1.4e-32	SMART
Pfam:TIL	720	773	3.3e-14	PFAM
VWC	775	829	9.42e-1	SMART
VWD	824	990	7.86e-44	SMART
C8	1034	1109	1.66e-34	SMART
Pfam:TIL	1112	1165	6.9e-13	PFAM
VWC	1167	1225	9.8e-3	SMART
FOLN	1198	1220	9.55e-1	SMART
FOLN	1224	1246	2.41e0	SMART
VWD	1243	1411	6.59e-37	SMART
C8	1451	1527	5.6e-32	SMART
low complexity region	1541	1551	N/A	INTRINSIC
EGF_like	1558	1581	6.15e1	SMART
VWC	1589	1682	1.6e-2	SMART
VWD	1640	1807	5.15e-39	SMART
C8	1839	1914	4.62e-33	SMART
EGF_like	1942	1965	4.46e1	SMART
VWC	1972	2064	1.92e-1	SMART
VWD	2024	2180	6.34e-39	SMART
low complexity region	2201	2214	N/A	INTRINSIC
C8	2221	2296	3.7e-32	SMART
Pfam:TIL	2299	2352	1e-11	PFAM
VWC	2354	2413	8.29e-1	SMART
FOLN	2385	2407	4.96e1	SMART
VWD	2404	2566	1.89e-5	SMART

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000148946

Coding Region Coverage

1x: 99.9%
3x: 99.5%
10x: 97.4%
20x: 91.8%

Validation Efficiency

96% (54/56)

Allele List at MGI

Other mutations in this stock

Total: 57 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
4930568D16Rik	T	G	2: 35,252,348 (GRCm39)	T50P	possibly damaging	Het
Adad1	A	G	3: 37,139,118 (GRCm39)	E396G	possibly damaging	Het
Adamtsl3	T	A	7: 82,114,829 (GRCm39)	C232S	probably damaging	Het
AI606181	T	C	19: 41,582,063 (GRCm39)	S78P	unknown	Het
Amph	T	A	13: 19,309,293 (GRCm39)	M457K	probably benign	Het
Ano1	A	T	7: 144,223,171 (GRCm39)	M174K	probably benign	Het
C3	T	A	17: 57,528,967 (GRCm39)	K632*	probably null	Het
Cep170	C	T	1: 176,583,397 (GRCm39)	G994D	probably damaging	Het
Chd7	T	C	4: 8,751,875 (GRCm39)	V124A	probably damaging	Het
Chd9	A	G	8: 91,761,691 (GRCm39)	K2259E	probably damaging	Het
Col7a1	A	G	9: 108,784,402 (GRCm39)	T137A	unknown	Het
Dcc	C	T	18: 71,942,185 (GRCm39)	V311I	probably benign	Het
Ddx42	A	T	11: 106,125,796 (GRCm39)	Q282L	probably damaging	Het
Fpr-rs3	A	G	17: 20,844,532 (GRCm39)	I203T	probably benign	Het
Frem1	A	G	4: 82,818,796 (GRCm39)	I2139T	probably benign	Het
Frmpd2	T	C	14: 33,244,820 (GRCm39)	V546A	probably damaging	Het
Gbp11	G	T	5: 105,479,254 (GRCm39)	T123N	possibly damaging	Het
Hs3st1	G	A	5: 39,772,007 (GRCm39)	P212L	probably damaging	Het
Ifnb1	T	A	4: 88,440,813 (GRCm39)	M67L	probably benign	Het
Ighv1-54	T	C	12: 115,157,497 (GRCm39)	N50S	probably benign	Het
Ikzf4	G	A	10: 128,470,542 (GRCm39)	T326I	probably benign	Het
Ints2	A	T	11: 86,127,429 (GRCm39)	V501E	probably damaging	Het
Mfsd1	C	A	3: 67,507,270 (GRCm39)		probably null	Het
Mroh2a	GCCC	GC	1: 88,159,979 (GRCm39)		probably null	Het
Mrps11	G	A	7: 78,438,466 (GRCm39)	A73T	possibly damaging	Het
Mterf4	T	C	1: 93,229,291 (GRCm39)	E311G	probably damaging	Het
Mx2	A	G	16: 97,347,635 (GRCm39)	T176A	probably damaging	Het
Mycbp2	A	C	14: 103,460,482 (GRCm39)	L1495R	probably damaging	Het
Myo3b	A	G	2: 70,069,113 (GRCm39)	T451A	probably benign	Het
Myrfl	T	C	10: 116,685,111 (GRCm39)	T90A	probably benign	Het
Nbeal1	A	G	1: 60,220,715 (GRCm39)		probably benign	Het
Ncor1	A	G	11: 62,310,443 (GRCm39)	L201P	probably damaging	Het
Nfxl1	G	T	5: 72,671,533 (GRCm39)	L909I	probably benign	Het
Nr3c1	GGCTGCTGCTGCTGCTGCTGCTGCTGCTGCTGCTGCTGCTGCTGCTGCTGCTGC	GGCTGCTGCTGCTGCTGCTGCTGCTGCTGCTGCTGCTGCTGCTGCTGCTGC	18: 39,620,011 (GRCm39)		probably benign	Het
Or5aq1b	T	A	2: 86,901,705 (GRCm39)	S258C	probably benign	Het
Plscr5	A	G	9: 92,086,437 (GRCm39)	T136A	probably benign	Het
Ppp1r3a	G	A	6: 14,719,339 (GRCm39)	T525I	probably benign	Het
Ptprg	G	A	14: 12,215,979 (GRCm38)	G1143R	probably damaging	Het
Rbm47	G	C	5: 66,183,626 (GRCm39)	R326G	probably damaging	Het
Ryr1	T	C	7: 28,771,398 (GRCm39)	T2541A	probably benign	Het
Sall1	A	G	8: 89,755,247 (GRCm39)	L1244P	probably damaging	Het
Sec16a	G	A	2: 26,316,482 (GRCm39)	H1673Y	probably damaging	Het
Slc22a19	A	G	19: 7,688,428 (GRCm39)	I44T	probably benign	Het
Snap91	T	A	9: 86,721,681 (GRCm39)	N53Y	probably damaging	Het
Sorcs1	T	C	19: 50,276,539 (GRCm39)	T338A	possibly damaging	Het
Taf6l	T	C	19: 8,755,920 (GRCm39)	T243A	probably benign	Het
Tex10	T	C	4: 48,459,891 (GRCm39)	R487G	probably damaging	Het
Tfcp2	G	T	15: 100,410,194 (GRCm39)	T391N	probably damaging	Het
Tnxb	G	A	17: 34,929,338 (GRCm39)	V2794M	probably damaging	Het
Ush2a	T	G	1: 188,132,000 (GRCm39)	C741G	probably damaging	Het
Vmn1r3	T	A	4: 3,184,684 (GRCm39)	I208F	probably damaging	Het
Vmn2r28	T	A	7: 5,496,790 (GRCm39)	I21F	possibly damaging	Het
Vmn2r93	A	G	17: 18,545,958 (GRCm39)	D610G	probably benign	Het
Wbp1	T	C	6: 83,096,468 (GRCm39)	S229G	probably benign	Het
Xirp1	A	G	9: 119,847,029 (GRCm39)	V618A	probably benign	Het
Zbtb32	A	G	7: 30,291,254 (GRCm39)	S14P	possibly damaging	Het
Zfp24	A	G	18: 24,147,269 (GRCm39)	S348P	probably damaging	Het

Other mutations in Fcgbp

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00309:Fcgbp	APN	7	27,784,555 (GRCm39)	missense	probably damaging	1.00
IGL00331:Fcgbp	APN	7	27,800,966 (GRCm39)	splice site	probably benign
IGL00335:Fcgbp	APN	7	27,785,560 (GRCm39)	missense	possibly damaging	0.90
IGL00470:Fcgbp	APN	7	27,774,511 (GRCm39)	nonsense	probably null
IGL00491:Fcgbp	APN	7	27,792,827 (GRCm39)	missense	probably damaging	1.00
IGL00498:Fcgbp	APN	7	27,791,222 (GRCm39)	missense	probably damaging	1.00
IGL01296:Fcgbp	APN	7	27,789,072 (GRCm39)	missense	probably benign	0.15
IGL01582:Fcgbp	APN	7	27,793,067 (GRCm39)	missense	probably benign	0.19
IGL01929:Fcgbp	APN	7	27,803,388 (GRCm39)	missense	probably damaging	1.00
IGL02024:Fcgbp	APN	7	27,805,799 (GRCm39)	missense	probably damaging	1.00
IGL02027:Fcgbp	APN	7	27,774,629 (GRCm39)	missense	probably damaging	1.00
IGL02140:Fcgbp	APN	7	27,791,379 (GRCm39)	missense	probably damaging	1.00
IGL02162:Fcgbp	APN	7	27,774,660 (GRCm39)	missense	probably damaging	1.00
IGL02345:Fcgbp	APN	7	27,771,068 (GRCm39)	splice site	probably benign
IGL02377:Fcgbp	APN	7	27,806,395 (GRCm39)	missense	possibly damaging	0.67
IGL02389:Fcgbp	APN	7	27,774,596 (GRCm39)	missense	probably damaging	1.00
IGL02423:Fcgbp	APN	7	27,789,378 (GRCm39)	missense	probably benign	0.02
IGL02523:Fcgbp	APN	7	27,804,157 (GRCm39)	missense	possibly damaging	0.89
IGL02561:Fcgbp	APN	7	27,800,599 (GRCm39)	intron	probably benign
IGL02631:Fcgbp	APN	7	27,784,723 (GRCm39)	missense	probably damaging	1.00
IGL02716:Fcgbp	APN	7	27,800,859 (GRCm39)	missense	probably damaging	0.98
IGL02836:Fcgbp	APN	7	27,816,783 (GRCm39)	missense	possibly damaging	0.91
IGL02957:Fcgbp	APN	7	27,791,272 (GRCm39)	nonsense	probably null
IGL02971:Fcgbp	APN	7	27,800,898 (GRCm39)	missense	probably damaging	1.00
IGL03284:Fcgbp	APN	7	27,784,857 (GRCm39)	missense	possibly damaging	0.93
IGL03379:Fcgbp	APN	7	27,789,342 (GRCm39)	missense	possibly damaging	0.76
bilge	UTSW	7	27,816,762 (GRCm39)	missense	probably benign	0.00
R6548_fcgbp_365	UTSW	7	27,791,343 (GRCm39)	missense	probably benign	0.00
swill	UTSW	7	27,789,159 (GRCm39)	missense	probably damaging	1.00
G1citation:Fcgbp	UTSW	7	27,806,781 (GRCm39)	missense	probably damaging	1.00
IGL02796:Fcgbp	UTSW	7	27,800,576 (GRCm39)	intron	probably benign
PIT4486001:Fcgbp	UTSW	7	27,774,698 (GRCm39)	missense	possibly damaging	0.52
R0277:Fcgbp	UTSW	7	27,784,918 (GRCm39)	critical splice donor site	probably null
R0387:Fcgbp	UTSW	7	27,790,879 (GRCm39)	splice site	probably benign
R0586:Fcgbp	UTSW	7	27,789,138 (GRCm39)	missense	probably damaging	1.00
R0981:Fcgbp	UTSW	7	27,784,535 (GRCm39)	nonsense	probably null
R0987:Fcgbp	UTSW	7	27,793,599 (GRCm39)	missense	probably damaging	1.00
R1240:Fcgbp	UTSW	7	27,819,950 (GRCm39)	missense	probably damaging	1.00
R1394:Fcgbp	UTSW	7	27,792,804 (GRCm39)	missense	probably damaging	0.98
R1395:Fcgbp	UTSW	7	27,792,804 (GRCm39)	missense	probably damaging	0.98
R1438:Fcgbp	UTSW	7	27,803,158 (GRCm39)	nonsense	probably null
R1474:Fcgbp	UTSW	7	27,791,273 (GRCm39)	missense	probably benign	0.00
R1521:Fcgbp	UTSW	7	27,774,585 (GRCm39)	missense	probably benign	0.00
R1740:Fcgbp	UTSW	7	27,800,674 (GRCm39)	missense	possibly damaging	0.87
R1750:Fcgbp	UTSW	7	27,792,868 (GRCm39)	nonsense	probably null
R1772:Fcgbp	UTSW	7	27,804,600 (GRCm39)	missense	possibly damaging	0.90
R1804:Fcgbp	UTSW	7	27,785,564 (GRCm39)	missense	probably benign
R1808:Fcgbp	UTSW	7	27,784,515 (GRCm39)	missense	probably benign	0.04
R1819:Fcgbp	UTSW	7	27,784,708 (GRCm39)	missense	probably benign	0.00
R1934:Fcgbp	UTSW	7	27,806,518 (GRCm39)	missense	probably damaging	1.00
R1972:Fcgbp	UTSW	7	27,793,617 (GRCm39)	missense	probably benign	0.11
R2051:Fcgbp	UTSW	7	27,819,785 (GRCm39)	missense	probably damaging	0.97
R2072:Fcgbp	UTSW	7	27,819,814 (GRCm39)	missense	probably damaging	0.98
R2074:Fcgbp	UTSW	7	27,819,814 (GRCm39)	missense	probably damaging	0.98
R2124:Fcgbp	UTSW	7	27,791,444 (GRCm39)	missense	probably benign	0.03
R2155:Fcgbp	UTSW	7	27,806,628 (GRCm39)	missense	probably benign	0.00
R3015:Fcgbp	UTSW	7	27,774,838 (GRCm39)	splice site	probably benign
R3037:Fcgbp	UTSW	7	27,802,127 (GRCm39)	missense	possibly damaging	0.62
R3151:Fcgbp	UTSW	7	27,816,665 (GRCm39)	missense	probably damaging	1.00
R3176:Fcgbp	UTSW	7	27,791,086 (GRCm39)	missense	probably damaging	0.99
R3177:Fcgbp	UTSW	7	27,791,086 (GRCm39)	missense	probably damaging	0.99
R3276:Fcgbp	UTSW	7	27,791,086 (GRCm39)	missense	probably damaging	0.99
R3277:Fcgbp	UTSW	7	27,791,086 (GRCm39)	missense	probably damaging	0.99
R3623:Fcgbp	UTSW	7	27,800,701 (GRCm39)	missense	probably damaging	1.00
R3730:Fcgbp	UTSW	7	27,784,882 (GRCm39)	missense	possibly damaging	0.82
R3935:Fcgbp	UTSW	7	27,774,824 (GRCm39)	missense	probably benign	0.00
R3936:Fcgbp	UTSW	7	27,774,824 (GRCm39)	missense	probably benign	0.00
R4041:Fcgbp	UTSW	7	27,813,404 (GRCm39)	missense	probably benign	0.01
R4056:Fcgbp	UTSW	7	27,803,541 (GRCm39)	missense	probably benign	0.09
R4057:Fcgbp	UTSW	7	27,803,541 (GRCm39)	missense	probably benign	0.09
R4705:Fcgbp	UTSW	7	27,806,721 (GRCm39)	missense	probably benign	0.44
R4708:Fcgbp	UTSW	7	27,794,386 (GRCm39)	missense	probably benign	0.00
R4710:Fcgbp	UTSW	7	27,794,386 (GRCm39)	missense	probably benign	0.00
R4779:Fcgbp	UTSW	7	27,794,362 (GRCm39)	missense	probably damaging	1.00
R4820:Fcgbp	UTSW	7	27,813,383 (GRCm39)	missense	probably damaging	1.00
R4863:Fcgbp	UTSW	7	27,785,769 (GRCm39)	missense	probably benign	0.33
R4926:Fcgbp	UTSW	7	27,785,660 (GRCm39)	missense	probably damaging	0.99
R4947:Fcgbp	UTSW	7	27,789,237 (GRCm39)	missense	probably benign	0.00
R4979:Fcgbp	UTSW	7	27,816,995 (GRCm39)	missense	probably benign	0.06
R5002:Fcgbp	UTSW	7	27,785,528 (GRCm39)	splice site	probably null
R5219:Fcgbp	UTSW	7	27,803,510 (GRCm39)	missense	probably damaging	1.00
R5241:Fcgbp	UTSW	7	27,784,624 (GRCm39)	missense	probably damaging	1.00
R5301:Fcgbp	UTSW	7	27,793,099 (GRCm39)	missense	possibly damaging	0.93
R5306:Fcgbp	UTSW	7	27,791,243 (GRCm39)	missense	probably damaging	1.00
R5335:Fcgbp	UTSW	7	27,789,159 (GRCm39)	missense	probably damaging	1.00
R5399:Fcgbp	UTSW	7	27,804,480 (GRCm39)	missense	probably benign	0.05
R5418:Fcgbp	UTSW	7	27,784,738 (GRCm39)	missense	probably damaging	1.00
R5527:Fcgbp	UTSW	7	27,793,060 (GRCm39)	missense	probably benign
R5583:Fcgbp	UTSW	7	27,791,004 (GRCm39)	missense	probably damaging	1.00
R5698:Fcgbp	UTSW	7	27,791,447 (GRCm39)	missense	possibly damaging	0.95
R5780:Fcgbp	UTSW	7	27,784,643 (GRCm39)	missense	probably benign	0.02
R5813:Fcgbp	UTSW	7	27,800,919 (GRCm39)	missense	possibly damaging	0.64
R5910:Fcgbp	UTSW	7	27,784,928 (GRCm39)	splice site	probably benign
R5936:Fcgbp	UTSW	7	27,786,117 (GRCm39)	missense	probably damaging	0.98
R5992:Fcgbp	UTSW	7	27,819,959 (GRCm39)	missense	probably benign	0.05
R6372:Fcgbp	UTSW	7	27,806,433 (GRCm39)	missense	probably damaging	1.00
R6488:Fcgbp	UTSW	7	27,792,963 (GRCm39)	missense	probably damaging	0.96
R6548:Fcgbp	UTSW	7	27,791,343 (GRCm39)	missense	probably benign	0.00
R6553:Fcgbp	UTSW	7	27,813,404 (GRCm39)	missense	possibly damaging	0.79
R6585:Fcgbp	UTSW	7	27,813,404 (GRCm39)	missense	possibly damaging	0.79
R6695:Fcgbp	UTSW	7	27,785,695 (GRCm39)	nonsense	probably null
R6711:Fcgbp	UTSW	7	27,789,098 (GRCm39)	missense	probably damaging	0.99
R6803:Fcgbp	UTSW	7	27,802,637 (GRCm39)	missense	probably benign	0.00
R6822:Fcgbp	UTSW	7	27,806,781 (GRCm39)	missense	probably damaging	1.00
R6907:Fcgbp	UTSW	7	27,784,443 (GRCm39)	missense	probably damaging	1.00
R6912:Fcgbp	UTSW	7	27,789,129 (GRCm39)	missense	probably benign	0.15
R6924:Fcgbp	UTSW	7	27,793,248 (GRCm39)	missense	probably benign
R6943:Fcgbp	UTSW	7	27,791,477 (GRCm39)	missense	probably benign	0.22
R7060:Fcgbp	UTSW	7	27,791,358 (GRCm39)	missense	probably benign	0.20
R7103:Fcgbp	UTSW	7	27,784,387 (GRCm39)	missense	probably benign	0.00
R7208:Fcgbp	UTSW	7	27,803,446 (GRCm39)	missense	probably benign	0.01
R7291:Fcgbp	UTSW	7	27,800,817 (GRCm39)	missense	probably benign	0.00
R7301:Fcgbp	UTSW	7	27,792,861 (GRCm39)	missense	possibly damaging	0.65
R7404:Fcgbp	UTSW	7	27,800,932 (GRCm39)	missense	probably damaging	1.00
R7426:Fcgbp	UTSW	7	27,785,949 (GRCm39)	missense	probably benign	0.00
R7459:Fcgbp	UTSW	7	27,806,710 (GRCm39)	missense	possibly damaging	0.65
R7475:Fcgbp	UTSW	7	27,802,401 (GRCm39)	missense	probably damaging	0.99
R7505:Fcgbp	UTSW	7	27,789,099 (GRCm39)	missense	probably damaging	0.97
R7517:Fcgbp	UTSW	7	27,784,794 (GRCm39)	missense	probably damaging	1.00
R7519:Fcgbp	UTSW	7	27,785,724 (GRCm39)	missense	probably damaging	1.00
R7524:Fcgbp	UTSW	7	27,802,391 (GRCm39)	missense	probably damaging	1.00
R7649:Fcgbp	UTSW	7	27,790,928 (GRCm39)	missense	possibly damaging	0.88
R7782:Fcgbp	UTSW	7	27,784,460 (GRCm39)	nonsense	probably null
R7820:Fcgbp	UTSW	7	27,819,784 (GRCm39)	missense	probably benign	0.01
R7831:Fcgbp	UTSW	7	27,806,404 (GRCm39)	missense	probably damaging	0.98
R7835:Fcgbp	UTSW	7	27,816,632 (GRCm39)	missense	possibly damaging	0.64
R7947:Fcgbp	UTSW	7	27,803,595 (GRCm39)	critical splice donor site	probably null
R8086:Fcgbp	UTSW	7	27,813,389 (GRCm39)	missense	probably damaging	1.00
R8137:Fcgbp	UTSW	7	27,804,496 (GRCm39)	missense	probably damaging	1.00
R8154:Fcgbp	UTSW	7	27,784,507 (GRCm39)	missense	probably benign	0.00
R8169:Fcgbp	UTSW	7	27,784,919 (GRCm39)	critical splice donor site	probably null
R8176:Fcgbp	UTSW	7	27,791,174 (GRCm39)	missense	possibly damaging	0.88
R8193:Fcgbp	UTSW	7	27,804,276 (GRCm39)	missense	probably damaging	1.00
R8313:Fcgbp	UTSW	7	27,785,769 (GRCm39)	missense	probably benign	0.00
R8350:Fcgbp	UTSW	7	27,793,614 (GRCm39)	missense	probably benign	0.02
R8382:Fcgbp	UTSW	7	27,816,762 (GRCm39)	missense	probably benign	0.00
R8393:Fcgbp	UTSW	7	27,806,815 (GRCm39)	missense	probably benign	0.18
R8438:Fcgbp	UTSW	7	27,789,231 (GRCm39)	missense	probably benign	0.25
R8489:Fcgbp	UTSW	7	27,804,435 (GRCm39)	missense	possibly damaging	0.94
R8495:Fcgbp	UTSW	7	27,785,978 (GRCm39)	missense	probably damaging	1.00
R8707:Fcgbp	UTSW	7	27,819,920 (GRCm39)	missense	probably benign	0.01
R8736:Fcgbp	UTSW	7	27,805,621 (GRCm39)	missense	probably benign	0.05
R8816:Fcgbp	UTSW	7	27,784,412 (GRCm39)	missense	probably benign	0.09
R8905:Fcgbp	UTSW	7	27,785,934 (GRCm39)	missense	probably damaging	1.00
R9031:Fcgbp	UTSW	7	27,790,908 (GRCm39)	missense	possibly damaging	0.89
R9063:Fcgbp	UTSW	7	27,791,277 (GRCm39)	missense	probably damaging	1.00
R9180:Fcgbp	UTSW	7	27,803,198 (GRCm39)	nonsense	probably null
R9262:Fcgbp	UTSW	7	27,819,952 (GRCm39)	missense	probably damaging	1.00
R9439:Fcgbp	UTSW	7	27,803,436 (GRCm39)	missense	possibly damaging	0.60
R9526:Fcgbp	UTSW	7	27,790,937 (GRCm39)	missense	probably damaging	1.00
R9603:Fcgbp	UTSW	7	27,802,563 (GRCm39)	missense	probably damaging	1.00
R9635:Fcgbp	UTSW	7	27,800,832 (GRCm39)	missense	probably benign	0.40
R9703:Fcgbp	UTSW	7	27,806,400 (GRCm39)	missense	probably damaging	0.98
R9711:Fcgbp	UTSW	7	27,793,000 (GRCm39)	missense	probably benign	0.00
R9733:Fcgbp	UTSW	7	27,803,012 (GRCm39)	missense	probably damaging	1.00
RF002:Fcgbp	UTSW	7	27,789,180 (GRCm39)	missense	probably benign
X0028:Fcgbp	UTSW	7	27,803,445 (GRCm39)	missense	possibly damaging	0.48
Z1186:Fcgbp	UTSW	7	27,791,072 (GRCm39)	missense	probably benign
Z1186:Fcgbp	UTSW	7	27,789,180 (GRCm39)	missense	probably benign
Z1186:Fcgbp	UTSW	7	27,785,616 (GRCm39)	missense	probably benign
Z1186:Fcgbp	UTSW	7	27,803,309 (GRCm39)	missense	probably benign	0.09
Z1186:Fcgbp	UTSW	7	27,792,770 (GRCm39)	missense	probably benign

Predicted Primers

PCR Primer
(F):5'- TAGTGAACACTGCTTCGGGG -3'
(R):5'- CATAGGTGGCTATAGCAGGAC -3'

Sequencing Primer
(F):5'- ACGGAGACAGTTTCGTGC -3'
(R):5'- ACAGAGGCCACCTGGATGTC -3'

Posted On

2017-08-16