Mutagenetix > Incidental Mutation

Incidental Mutation 'R6031:Fat3'

486280

Institutional Source

Beutler Lab

Gene Symbol

Fat3

Ensembl Gene

ENSMUSG00000074505

Gene Name

FAT atypical cadherin 3

Synonyms

9430076A06Rik, D430038H04Rik, LOC382129, LOC234973

MMRRC Submission

044203-MU

Accession Numbers

Genbank: NM_001080814; MGI: 2444314

Essential gene?

Possibly non essential (E-score: 0.417) question?

Stock #

R6031 (G1)

Quality Score

225.009

Status

Not validated

Chromosome

Chromosomal Location

15910189-16501285 bp(-) (GRCm38)

Type of Mutation

missense

DNA Base Change (assembly)

T to A at 15988492 bp (GRCm38)

Zygosity

Heterozygous

Amino Acid Change

Threonine to Serine at position 3082 (T3082S)

Ref Sequence

ENSEMBL: ENSMUSP00000148968 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000082170] [ENSMUST00000217308]

AlphaFold

no structure available at present

Predicted Effect

probably benign
Transcript: ENSMUST00000082170
AA Change: T3082S

PolyPhen 2 Score 0.016 (Sensitivity: 0.95; Specificity: 0.79)

SMART Domains

Protein: ENSMUSP00000080808
Gene: ENSMUSG00000074505
AA Change: T3082S

Domain	Start	End	E-Value	Type
signal peptide	1	27	N/A	INTRINSIC
CA	65	151	3e-7	SMART
CA	175	259	8.9e-22	SMART
CA	280	368	8.9e-4	SMART
CA	389	465	2.6e-11	SMART
CA	489	571	2e-29	SMART
low complexity region	684	697	N/A	INTRINSIC
CA	743	824	1e-24	SMART
low complexity region	830	840	N/A	INTRINSIC
CA	848	929	7.6e-26	SMART
CA	953	1034	1.5e-25	SMART
CA	1060	1141	6.6e-32	SMART
CA	1165	1247	1.5e-30	SMART
CA	1273	1349	1.8e-8	SMART
CA	1375	1453	2.9e-12	SMART
CA	1477	1559	3e-22	SMART
CA	1583	1664	3.1e-16	SMART
CA	1688	1762	4.2e-22	SMART
CA	1793	1876	2.5e-26	SMART
CA	1900	1975	1.5e-8	SMART
low complexity region	1983	1994	N/A	INTRINSIC
CA	1999	2077	1.4e-18	SMART
CA	2101	2179	6.6e-10	SMART
CA	2203	2280	4.9e-19	SMART
CA	2304	2387	4.3e-29	SMART
CA	2411	2489	4.2e-11	SMART
CA	2513	2593	2.8e-22	SMART
CA	2617	2701	4.3e-10	SMART
CA	2719	2807	2.5e-7	SMART
CA	2831	2917	3.3e-27	SMART
CA	2941	3022	9.4e-23	SMART
CA	3046	3124	2.4e-26	SMART
CA	3148	3229	1.3e-32	SMART
CA	3253	3334	1.3e-29	SMART
CA	3358	3439	4.9e-28	SMART
CA	3463	3544	6.4e-12	SMART
EGF	3793	3828	1.3e-1	SMART
LamG	3852	3989	4.3e-25	SMART
EGF	4019	4053	2.7e-6	SMART
EGF	4058	4091	4.5e-6	SMART
EGF_CA	4093	4129	3.9e-11	SMART
transmembrane domain	4151	4170	N/A	INTRINSIC

Predicted Effect

probably benign
Transcript: ENSMUST00000217308
AA Change: T3082S

PolyPhen 2 Score 0.016 (Sensitivity: 0.95; Specificity: 0.79)

Coding Region Coverage

1x: 99.9%
3x: 99.7%
10x: 98.4%
20x: 95.6%

Validation Efficiency

MGI Phenotype

PHENOTYPE: Mice homozgyous for a knock-out allele exhibit abnormal amacrine cell differentiation and migration that result in the formation of two additional plexiform layers and thickened retinal ganglion layer. [provided by MGI curators]

Allele List at MGI

All alleles(3) : Gene trapped(3)

Other mutations in this stock

Total: 65 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
1700010I14Rik	T	C	17: 8,995,252 (GRCm38)	Y304H	possibly damaging	Het
Add2	A	G	6: 86,098,673 (GRCm38)	E268G	probably damaging	Het
Akr1b3	A	C	6: 34,312,674 (GRCm38)	V67G	probably benign	Het
Alms1	A	T	6: 85,622,955 (GRCm38)	N1588Y	probably damaging	Het
Arhgap23	A	T	11: 97,476,139 (GRCm38)	D1082V	probably damaging	Het
Asb6	A	G	2: 30,824,195 (GRCm38)	V301A	probably benign	Het
Ascc3	C	T	10: 50,842,183 (GRCm38)	R1991*	probably null	Het
Atg7	T	A	6: 114,671,233 (GRCm38)	C31S	probably benign	Het
Camsap2	A	T	1: 136,280,438 (GRCm38)	N1105K	possibly damaging	Het
Ccdc125	C	T	13: 100,684,369 (GRCm38)		probably null	Het
Ccdc63	T	C	5: 122,129,736 (GRCm38)	I56V	possibly damaging	Het
Cpd	T	C	11: 76,790,888 (GRCm38)	E1143G	probably benign	Het
Cpt1a	T	A	19: 3,371,556 (GRCm38)		probably null	Het
Creb3l2	A	T	6: 37,334,434 (GRCm38)	D473E	probably benign	Het
Disp2	G	T	2: 118,789,794 (GRCm38)	V336L	probably benign	Het
Efr3b	A	G	12: 3,967,106 (GRCm38)	I782T	possibly damaging	Het
Fam98a	A	G	17: 75,539,432 (GRCm38)	V230A	probably damaging	Het
Frmd3	T	C	4: 74,187,451 (GRCm38)	Y445H	probably damaging	Het
Galt	G	A	4: 41,757,202 (GRCm38)	R185Q	probably benign	Het
Gatb	T	C	3: 85,613,511 (GRCm38)	I309T	possibly damaging	Het
Gfi1b	G	A	2: 28,613,808 (GRCm38)	Q127*	probably null	Het
Gfpt1	C	A	6: 87,086,320 (GRCm38)	T563N	probably damaging	Het
Gria1	A	G	11: 57,217,782 (GRCm38)	D237G	probably damaging	Het
Hspbp1	A	T	7: 4,663,466 (GRCm38)	V305D	probably benign	Het
Hyls1	G	A	9: 35,561,184 (GRCm38)	S312F	probably benign	Het
Iars	T	C	13: 49,705,831 (GRCm38)	V9A	probably damaging	Het
Ipo4	G	A	14: 55,632,139 (GRCm38)	P355S	probably damaging	Het
Jade2	G	T	11: 51,826,586 (GRCm38)	C314*	probably null	Het
Kri1	T	C	9: 21,275,269 (GRCm38)	E597G	probably benign	Het
Mcub	A	G	3: 129,926,389 (GRCm38)	Y152H	probably damaging	Het
Med23	C	T	10: 24,903,748 (GRCm38)	R542*	probably null	Het
Ndc80	T	C	17: 71,511,488 (GRCm38)	N291S	probably benign	Het
Nop2	T	C	6: 125,133,566 (GRCm38)		probably null	Het
Nrxn1	T	C	17: 90,588,790 (GRCm38)	N984S	probably damaging	Het
Ntm	A	C	9: 29,009,375 (GRCm38)	L86R	probably damaging	Het
Numa1	T	A	7: 102,012,012 (GRCm38)	D1847E	possibly damaging	Het
Odf2l	A	G	3: 145,139,863 (GRCm38)	Q334R	probably damaging	Het
Olfr1238	T	A	2: 89,406,972 (GRCm38)	T36S	probably damaging	Het
Olfr1333	A	T	4: 118,830,391 (GRCm38)		probably null	Het
Olfr199	T	C	16: 59,215,933 (GRCm38)	R227G	probably benign	Het
Olfr522	A	T	7: 140,162,809 (GRCm38)	V47E	possibly damaging	Het
Olfr706	C	T	7: 106,885,927 (GRCm38)	V297I	possibly damaging	Het
Olfr772	A	G	10: 129,174,355 (GRCm38)	V222A	probably benign	Het
Pcdhb19	A	T	18: 37,497,723 (GRCm38)	K190N	probably damaging	Het
Pdik1l	A	G	4: 134,279,041 (GRCm38)	F197L	probably damaging	Het
Rnf113a2	T	C	12: 84,417,990 (GRCm38)	F219L	probably damaging	Het
Rnf208	A	C	2: 25,243,764 (GRCm38)	T157P	probably damaging	Het
RP23-145I16.3	A	T	7: 142,376,714 (GRCm38)	C364S	probably damaging	Het
Scn8a	A	T	15: 100,983,984 (GRCm38)	D644V	probably damaging	Het
Thbs3	T	A	3: 89,218,094 (GRCm38)	C204S	probably damaging	Het
Tlr3	A	G	8: 45,398,528 (GRCm38)	I444T	probably damaging	Het
Tmem206	A	G	1: 191,340,840 (GRCm38)	R153G	probably benign	Het
Trpm8	A	T	1: 88,354,469 (GRCm38)	I696F	possibly damaging	Het
Ttn	A	T	2: 76,830,597 (GRCm38)	V7422D	possibly damaging	Het
Ufl1	A	G	4: 25,278,038 (GRCm38)	V139A	probably benign	Het
Uggt2	A	T	14: 119,070,826 (GRCm38)	V381D	probably benign	Het
Vgll3	T	A	16: 65,839,481 (GRCm38)	Y173N	probably damaging	Het
Vmn1r9	A	G	6: 57,071,173 (GRCm38)	T78A	probably benign	Het
Vps13b	T	A	15: 35,471,968 (GRCm38)	L806M	probably damaging	Het
Vps13d	A	C	4: 145,168,509 (GRCm38)	H394Q	probably benign	Het
Wdr53	T	A	16: 32,256,718 (GRCm38)	V247D	probably damaging	Het
Wdr81	A	T	11: 75,447,869 (GRCm38)	L1488Q	probably damaging	Het
Zc3h6	A	G	2: 128,967,812 (GRCm38)	D3G	possibly damaging	Het
Zfp93	G	T	7: 24,276,300 (GRCm38)	C570F	probably damaging	Het
Zfp943	C	T	17: 21,993,376 (GRCm38)	T481I	probably benign	Het

Other mutations in Fat3

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00662:Fat3	APN	9	15,996,427 (GRCm38)	missense	possibly damaging	0.77
IGL00962:Fat3	APN	9	15,915,519 (GRCm38)	missense	probably benign	0.14
IGL00966:Fat3	APN	9	15,999,094 (GRCm38)	missense	possibly damaging	0.69
IGL01100:Fat3	APN	9	16,375,228 (GRCm38)	missense	probably damaging	1.00
IGL01104:Fat3	APN	9	16,375,728 (GRCm38)	missense	possibly damaging	0.92
IGL01104:Fat3	APN	9	15,998,460 (GRCm38)	missense	probably damaging	1.00
IGL01121:Fat3	APN	9	15,998,401 (GRCm38)	missense	probably benign	0.00
IGL01407:Fat3	APN	9	16,378,023 (GRCm38)	missense	probably benign	0.01
IGL01444:Fat3	APN	9	15,998,848 (GRCm38)	missense	probably damaging	1.00
IGL01634:Fat3	APN	9	15,998,358 (GRCm38)	missense	probably damaging	1.00
IGL01649:Fat3	APN	9	16,376,719 (GRCm38)	missense	possibly damaging	0.95
IGL01839:Fat3	APN	9	15,997,872 (GRCm38)	missense	probably damaging	1.00
IGL01867:Fat3	APN	9	16,377,901 (GRCm38)	missense	probably benign	0.03
IGL01894:Fat3	APN	9	16,375,849 (GRCm38)	missense	probably benign
IGL01913:Fat3	APN	9	15,998,790 (GRCm38)	missense	probably damaging	0.99
IGL02033:Fat3	APN	9	15,915,352 (GRCm38)	missense	possibly damaging	0.50
IGL02035:Fat3	APN	9	16,377,970 (GRCm38)	missense	probably benign	0.06
IGL02146:Fat3	APN	9	15,999,582 (GRCm38)	missense	probably benign
IGL02147:Fat3	APN	9	15,995,985 (GRCm38)	missense	probably damaging	1.00
IGL02161:Fat3	APN	9	15,997,050 (GRCm38)	missense	probably benign	0.10
IGL02161:Fat3	APN	9	15,997,051 (GRCm38)	nonsense	probably null
IGL02164:Fat3	APN	9	16,031,424 (GRCm38)	splice site	probably benign
IGL02269:Fat3	APN	9	15,915,577 (GRCm38)	missense	possibly damaging	0.84
IGL02314:Fat3	APN	9	15,969,838 (GRCm38)	missense	possibly damaging	0.61
IGL02393:Fat3	APN	9	15,988,412 (GRCm38)	nonsense	probably null
IGL02410:Fat3	APN	9	15,997,845 (GRCm38)	missense	probably damaging	1.00
IGL02504:Fat3	APN	9	15,959,798 (GRCm38)	missense	probably damaging	1.00
IGL02572:Fat3	APN	9	15,960,506 (GRCm38)	missense	probably benign
IGL02623:Fat3	APN	9	15,997,137 (GRCm38)	missense	probably damaging	1.00
IGL02654:Fat3	APN	9	15,996,975 (GRCm38)	missense	possibly damaging	0.84
IGL02749:Fat3	APN	9	16,006,711 (GRCm38)	missense	possibly damaging	0.93
IGL02810:Fat3	APN	9	16,376,850 (GRCm38)	missense	probably damaging	1.00
IGL02839:Fat3	APN	9	15,919,170 (GRCm38)	missense	probably damaging	1.00
IGL02890:Fat3	APN	9	15,915,340 (GRCm38)	missense	probably benign	0.03
IGL02892:Fat3	APN	9	16,377,562 (GRCm38)	missense	probably damaging	1.00
IGL03090:Fat3	APN	9	16,377,239 (GRCm38)	nonsense	probably null
IGL03144:Fat3	APN	9	16,375,245 (GRCm38)	missense	probably damaging	1.00
IGL03199:Fat3	APN	9	16,377,048 (GRCm38)	missense	possibly damaging	0.83
IGL03365:Fat3	APN	9	15,996,469 (GRCm38)	missense	probably damaging	1.00
IGL03392:Fat3	APN	9	16,003,862 (GRCm38)	missense	probably benign
IGL03408:Fat3	APN	9	15,997,957 (GRCm38)	nonsense	probably null
gagged	UTSW	9	15,998,271 (GRCm38)	missense	probably damaging	1.00
hushed	UTSW	9	15,959,869 (GRCm38)	missense	possibly damaging	0.72
Muffled	UTSW	9	15,937,991 (GRCm38)	critical splice donor site	probably null
muted	UTSW	9	15,997,477 (GRCm38)	missense	possibly damaging	0.93
Softened	UTSW	9	16,378,185 (GRCm38)	missense	probably benign
BB001:Fat3	UTSW	9	15,999,297 (GRCm38)	missense	probably damaging	1.00
BB002:Fat3	UTSW	9	16,031,360 (GRCm38)	missense	possibly damaging	0.77
BB011:Fat3	UTSW	9	15,999,297 (GRCm38)	missense	probably damaging	1.00
BB012:Fat3	UTSW	9	16,031,360 (GRCm38)	missense	possibly damaging	0.77
F6893:Fat3	UTSW	9	16,006,789 (GRCm38)	missense	probably damaging	0.99
IGL03050:Fat3	UTSW	9	15,996,600 (GRCm38)	missense	probably benign	0.04
PIT4142001:Fat3	UTSW	9	15,992,118 (GRCm38)	critical splice donor site	probably null
PIT4283001:Fat3	UTSW	9	16,006,601 (GRCm38)	missense	possibly damaging	0.77
PIT4378001:Fat3	UTSW	9	16,376,808 (GRCm38)	missense	probably benign	0.05
PIT4434001:Fat3	UTSW	9	15,996,316 (GRCm38)	missense	probably benign	0.00
PIT4468001:Fat3	UTSW	9	15,996,351 (GRCm38)	missense	probably benign	0.06
R0001:Fat3	UTSW	9	16,377,873 (GRCm38)	missense	probably damaging	0.99
R0005:Fat3	UTSW	9	15,962,866 (GRCm38)	missense	probably damaging	1.00
R0005:Fat3	UTSW	9	15,962,866 (GRCm38)	missense	probably damaging	1.00
R0038:Fat3	UTSW	9	15,915,010 (GRCm38)	missense	probably damaging	1.00
R0046:Fat3	UTSW	9	15,965,979 (GRCm38)	missense	possibly damaging	0.65
R0089:Fat3	UTSW	9	15,938,205 (GRCm38)	missense	probably benign
R0135:Fat3	UTSW	9	16,006,777 (GRCm38)	missense	probably damaging	1.00
R0255:Fat3	UTSW	9	15,969,706 (GRCm38)	splice site	probably benign
R0349:Fat3	UTSW	9	16,031,180 (GRCm38)	missense	probably damaging	1.00
R0361:Fat3	UTSW	9	15,998,403 (GRCm38)	missense	possibly damaging	0.77
R0382:Fat3	UTSW	9	15,959,756 (GRCm38)	missense	probably damaging	1.00
R0418:Fat3	UTSW	9	16,246,896 (GRCm38)	missense	probably damaging	1.00
R0419:Fat3	UTSW	9	15,992,256 (GRCm38)	missense	probably damaging	1.00
R0437:Fat3	UTSW	9	15,996,932 (GRCm38)	missense	probably damaging	1.00
R0441:Fat3	UTSW	9	15,945,008 (GRCm38)	splice site	probably benign
R0480:Fat3	UTSW	9	15,997,729 (GRCm38)	missense	probably benign	0.00
R0510:Fat3	UTSW	9	15,999,685 (GRCm38)	nonsense	probably null
R0665:Fat3	UTSW	9	15,997,402 (GRCm38)	missense	probably benign
R0715:Fat3	UTSW	9	16,375,123 (GRCm38)	missense	probably benign
R0727:Fat3	UTSW	9	15,996,699 (GRCm38)	missense	probably damaging	1.00
R0882:Fat3	UTSW	9	16,031,368 (GRCm38)	missense	possibly damaging	0.84
R0946:Fat3	UTSW	9	15,997,804 (GRCm38)	missense	possibly damaging	0.95
R1068:Fat3	UTSW	9	15,970,034 (GRCm38)	missense	probably benign
R1081:Fat3	UTSW	9	16,375,284 (GRCm38)	missense	possibly damaging	0.62
R1082:Fat3	UTSW	9	16,006,615 (GRCm38)	missense	probably damaging	1.00
R1148:Fat3	UTSW	9	15,996,774 (GRCm38)	missense	probably damaging	1.00
R1148:Fat3	UTSW	9	15,996,774 (GRCm38)	missense	probably damaging	1.00
R1233:Fat3	UTSW	9	15,922,745 (GRCm38)	missense	probably benign
R1306:Fat3	UTSW	9	16,376,679 (GRCm38)	missense	probably damaging	1.00
R1311:Fat3	UTSW	9	16,021,410 (GRCm38)	missense	probably damaging	1.00
R1338:Fat3	UTSW	9	15,925,091 (GRCm38)	missense	probably benign	0.00
R1395:Fat3	UTSW	9	16,246,916 (GRCm38)	missense	probably benign	0.00
R1466:Fat3	UTSW	9	16,375,482 (GRCm38)	missense	probably damaging	0.96
R1466:Fat3	UTSW	9	16,375,482 (GRCm38)	missense	probably damaging	0.96
R1510:Fat3	UTSW	9	15,960,055 (GRCm38)	missense	probably damaging	1.00
R1528:Fat3	UTSW	9	15,925,091 (GRCm38)	missense	probably benign	0.00
R1531:Fat3	UTSW	9	15,997,465 (GRCm38)	missense	probably damaging	1.00
R1659:Fat3	UTSW	9	15,997,183 (GRCm38)	missense	possibly damaging	0.91
R1697:Fat3	UTSW	9	15,944,880 (GRCm38)	missense	probably benign	0.05
R1699:Fat3	UTSW	9	15,938,398 (GRCm38)	missense	probably damaging	1.00
R1728:Fat3	UTSW	9	15,996,315 (GRCm38)	missense	possibly damaging	0.65
R1729:Fat3	UTSW	9	15,996,315 (GRCm38)	missense	possibly damaging	0.65
R1731:Fat3	UTSW	9	15,995,937 (GRCm38)	missense	probably benign
R1784:Fat3	UTSW	9	15,996,315 (GRCm38)	missense	possibly damaging	0.65
R1789:Fat3	UTSW	9	16,376,985 (GRCm38)	missense	probably benign	0.00
R1794:Fat3	UTSW	9	15,997,138 (GRCm38)	missense	probably benign	0.15
R1794:Fat3	UTSW	9	15,997,136 (GRCm38)	nonsense	probably null
R1830:Fat3	UTSW	9	15,915,340 (GRCm38)	missense	probably benign	0.03
R1835:Fat3	UTSW	9	15,998,088 (GRCm38)	missense	probably damaging	1.00
R1887:Fat3	UTSW	9	15,967,061 (GRCm38)	missense	probably damaging	1.00
R1898:Fat3	UTSW	9	15,960,130 (GRCm38)	missense	probably damaging	1.00
R1909:Fat3	UTSW	9	15,998,115 (GRCm38)	missense	probably benign
R1912:Fat3	UTSW	9	15,969,988 (GRCm38)	missense	probably damaging	1.00
R1917:Fat3	UTSW	9	15,997,057 (GRCm38)	missense	possibly damaging	0.55
R1967:Fat3	UTSW	9	15,968,295 (GRCm38)	missense	probably benign	0.00
R2070:Fat3	UTSW	9	15,999,370 (GRCm38)	missense	probably benign	0.21
R2100:Fat3	UTSW	9	16,377,430 (GRCm38)	missense	possibly damaging	0.73
R2104:Fat3	UTSW	9	15,998,517 (GRCm38)	missense	possibly damaging	0.77
R2113:Fat3	UTSW	9	15,999,786 (GRCm38)	missense	probably damaging	1.00
R2132:Fat3	UTSW	9	16,246,719 (GRCm38)	critical splice donor site	probably null
R2136:Fat3	UTSW	9	16,377,051 (GRCm38)	missense	probably benign	0.01
R2146:Fat3	UTSW	9	15,990,512 (GRCm38)	missense	probably benign	0.01
R2233:Fat3	UTSW	9	15,998,271 (GRCm38)	missense	probably damaging	1.00
R2234:Fat3	UTSW	9	15,998,271 (GRCm38)	missense	probably damaging	1.00
R2273:Fat3	UTSW	9	15,915,262 (GRCm38)	missense	probably benign
R2285:Fat3	UTSW	9	16,376,173 (GRCm38)	missense	probably damaging	1.00
R2363:Fat3	UTSW	9	15,998,271 (GRCm38)	missense	probably damaging	1.00
R2365:Fat3	UTSW	9	15,998,271 (GRCm38)	missense	probably damaging	1.00
R2367:Fat3	UTSW	9	15,998,271 (GRCm38)	missense	probably damaging	1.00
R2403:Fat3	UTSW	9	15,969,871 (GRCm38)	missense	probably damaging	1.00
R2447:Fat3	UTSW	9	15,998,271 (GRCm38)	missense	probably damaging	1.00
R2496:Fat3	UTSW	9	15,966,103 (GRCm38)	missense	probably benign	0.01
R2509:Fat3	UTSW	9	15,925,014 (GRCm38)	missense	possibly damaging	0.82
R2932:Fat3	UTSW	9	16,375,944 (GRCm38)	missense	probably damaging	1.00
R2986:Fat3	UTSW	9	15,992,128 (GRCm38)	missense	probably damaging	1.00
R3054:Fat3	UTSW	9	15,960,496 (GRCm38)	missense	probably benign
R3056:Fat3	UTSW	9	15,960,496 (GRCm38)	missense	probably benign
R3729:Fat3	UTSW	9	16,247,041 (GRCm38)	splice site	probably benign
R3745:Fat3	UTSW	9	15,998,271 (GRCm38)	missense	probably damaging	1.00
R3806:Fat3	UTSW	9	15,998,271 (GRCm38)	missense	probably damaging	1.00
R3859:Fat3	UTSW	9	15,997,228 (GRCm38)	nonsense	probably null
R3862:Fat3	UTSW	9	15,998,271 (GRCm38)	missense	probably damaging	1.00
R3890:Fat3	UTSW	9	15,998,271 (GRCm38)	missense	probably damaging	1.00
R3892:Fat3	UTSW	9	15,998,271 (GRCm38)	missense	probably damaging	1.00
R3950:Fat3	UTSW	9	15,998,271 (GRCm38)	missense	probably damaging	1.00
R3972:Fat3	UTSW	9	15,998,271 (GRCm38)	missense	probably damaging	1.00
R4004:Fat3	UTSW	9	15,998,271 (GRCm38)	missense	probably damaging	1.00
R4005:Fat3	UTSW	9	15,998,271 (GRCm38)	missense	probably damaging	1.00
R4086:Fat3	UTSW	9	15,998,271 (GRCm38)	missense	probably damaging	1.00
R4111:Fat3	UTSW	9	15,998,271 (GRCm38)	missense	probably damaging	1.00
R4113:Fat3	UTSW	9	15,998,271 (GRCm38)	missense	probably damaging	1.00
R4227:Fat3	UTSW	9	16,377,693 (GRCm38)	missense	probably damaging	1.00
R4352:Fat3	UTSW	9	16,246,778 (GRCm38)	missense	possibly damaging	0.55
R4394:Fat3	UTSW	9	15,922,792 (GRCm38)	missense	probably benign	0.11
R4403:Fat3	UTSW	9	15,944,873 (GRCm38)	missense	probably damaging	1.00
R4433:Fat3	UTSW	9	16,031,152 (GRCm38)	missense	probably damaging	0.99
R4453:Fat3	UTSW	9	15,998,271 (GRCm38)	missense	probably damaging	1.00
R4479:Fat3	UTSW	9	15,998,271 (GRCm38)	missense	probably damaging	1.00
R4480:Fat3	UTSW	9	15,998,271 (GRCm38)	missense	probably damaging	1.00
R4521:Fat3	UTSW	9	15,922,942 (GRCm38)	missense	probably null	0.71
R4620:Fat3	UTSW	9	15,996,894 (GRCm38)	missense	probably damaging	1.00
R4700:Fat3	UTSW	9	16,031,173 (GRCm38)	missense	probably damaging	1.00
R4721:Fat3	UTSW	9	16,029,966 (GRCm38)	missense	probably damaging	1.00
R4790:Fat3	UTSW	9	15,998,484 (GRCm38)	missense	probably damaging	1.00
R4796:Fat3	UTSW	9	15,999,732 (GRCm38)	missense	probably benign	0.17
R4823:Fat3	UTSW	9	15,996,507 (GRCm38)	missense	probably benign
R4836:Fat3	UTSW	9	16,377,723 (GRCm38)	missense	probably damaging	1.00
R4842:Fat3	UTSW	9	15,997,587 (GRCm38)	missense	probably damaging	1.00
R4849:Fat3	UTSW	9	16,377,948 (GRCm38)	missense	probably benign	0.03
R4856:Fat3	UTSW	9	16,021,330 (GRCm38)	missense	probably benign
R4869:Fat3	UTSW	9	16,377,477 (GRCm38)	missense	probably damaging	0.98
R4886:Fat3	UTSW	9	16,021,330 (GRCm38)	missense	probably benign
R4899:Fat3	UTSW	9	15,969,799 (GRCm38)	missense	probably damaging	1.00
R4941:Fat3	UTSW	9	16,375,152 (GRCm38)	missense	probably damaging	1.00
R4986:Fat3	UTSW	9	15,998,340 (GRCm38)	missense	probably damaging	1.00
R5058:Fat3	UTSW	9	15,996,858 (GRCm38)	missense	probably damaging	1.00
R5079:Fat3	UTSW	9	15,999,127 (GRCm38)	missense	probably benign	0.01
R5080:Fat3	UTSW	9	15,999,338 (GRCm38)	missense	probably benign	0.35
R5174:Fat3	UTSW	9	15,999,570 (GRCm38)	missense	probably damaging	1.00
R5183:Fat3	UTSW	9	15,960,313 (GRCm38)	missense	probably damaging	0.99
R5203:Fat3	UTSW	9	16,378,142 (GRCm38)	missense	possibly damaging	0.79
R5216:Fat3	UTSW	9	16,377,537 (GRCm38)	missense	probably damaging	1.00
R5230:Fat3	UTSW	9	15,990,560 (GRCm38)	missense	possibly damaging	0.51
R5318:Fat3	UTSW	9	16,376,629 (GRCm38)	missense	probably damaging	1.00
R5377:Fat3	UTSW	9	16,376,443 (GRCm38)	missense	probably benign	0.05
R5385:Fat3	UTSW	9	15,922,675 (GRCm38)	missense	possibly damaging	0.82
R5436:Fat3	UTSW	9	15,960,514 (GRCm38)	missense	probably benign	0.02
R5437:Fat3	UTSW	9	16,085,308 (GRCm38)	missense	probably damaging	1.00
R5453:Fat3	UTSW	9	15,996,864 (GRCm38)	missense	probably damaging	1.00
R5460:Fat3	UTSW	9	15,919,167 (GRCm38)	missense	probably damaging	1.00
R5516:Fat3	UTSW	9	15,998,709 (GRCm38)	missense	probably damaging	1.00
R5568:Fat3	UTSW	9	16,376,923 (GRCm38)	nonsense	probably null
R5628:Fat3	UTSW	9	15,966,096 (GRCm38)	missense	probably damaging	1.00
R5835:Fat3	UTSW	9	16,375,833 (GRCm38)	missense	probably damaging	1.00
R5845:Fat3	UTSW	9	16,377,210 (GRCm38)	missense	probably damaging	1.00
R5898:Fat3	UTSW	9	15,938,461 (GRCm38)	missense	probably benign	0.15
R5941:Fat3	UTSW	9	15,999,501 (GRCm38)	missense	probably benign	0.07
R5974:Fat3	UTSW	9	16,006,528 (GRCm38)	critical splice donor site	probably null
R5986:Fat3	UTSW	9	15,998,317 (GRCm38)	missense	probably benign	0.22
R6015:Fat3	UTSW	9	16,376,050 (GRCm38)	missense	possibly damaging	0.55
R6031:Fat3	UTSW	9	15,988,492 (GRCm38)	missense	probably benign	0.02
R6042:Fat3	UTSW	9	16,377,817 (GRCm38)	missense	probably benign	0.12
R6051:Fat3	UTSW	9	16,375,455 (GRCm38)	missense	possibly damaging	0.83
R6052:Fat3	UTSW	9	15,922,679 (GRCm38)	missense	probably null
R6119:Fat3	UTSW	9	16,376,568 (GRCm38)	missense	possibly damaging	0.82
R6161:Fat3	UTSW	9	16,377,522 (GRCm38)	missense	probably damaging	1.00
R6254:Fat3	UTSW	9	15,996,145 (GRCm38)	missense	probably benign	0.19
R6318:Fat3	UTSW	9	15,916,984 (GRCm38)	intron	probably benign
R6347:Fat3	UTSW	9	15,998,372 (GRCm38)	missense	probably damaging	1.00
R6348:Fat3	UTSW	9	15,937,991 (GRCm38)	critical splice donor site	probably null
R6351:Fat3	UTSW	9	15,938,398 (GRCm38)	missense	probably damaging	1.00
R6450:Fat3	UTSW	9	15,999,170 (GRCm38)	missense	possibly damaging	0.51
R6460:Fat3	UTSW	9	15,967,000 (GRCm38)	missense	probably damaging	1.00
R6524:Fat3	UTSW	9	15,992,256 (GRCm38)	missense	probably damaging	1.00
R6533:Fat3	UTSW	9	15,998,899 (GRCm38)	missense	probably benign	0.02
R6565:Fat3	UTSW	9	15,915,327 (GRCm38)	missense	probably benign
R6576:Fat3	UTSW	9	16,377,210 (GRCm38)	missense	probably damaging	1.00
R6649:Fat3	UTSW	9	16,376,742 (GRCm38)	missense	probably damaging	1.00
R6716:Fat3	UTSW	9	15,919,269 (GRCm38)	missense	probably benign
R6719:Fat3	UTSW	9	15,996,144 (GRCm38)	missense	probably benign
R6753:Fat3	UTSW	9	15,915,061 (GRCm38)	missense	possibly damaging	0.82
R6754:Fat3	UTSW	9	15,915,061 (GRCm38)	missense	possibly damaging	0.82
R6755:Fat3	UTSW	9	15,915,061 (GRCm38)	missense	possibly damaging	0.82
R6792:Fat3	UTSW	9	16,375,644 (GRCm38)	missense	probably damaging	1.00
R6802:Fat3	UTSW	9	15,915,061 (GRCm38)	missense	possibly damaging	0.82
R6803:Fat3	UTSW	9	15,996,787 (GRCm38)	missense	probably damaging	0.99
R6831:Fat3	UTSW	9	16,376,551 (GRCm38)	missense	probably damaging	0.98
R6831:Fat3	UTSW	9	15,915,061 (GRCm38)	missense	possibly damaging	0.82
R6833:Fat3	UTSW	9	15,915,061 (GRCm38)	missense	possibly damaging	0.82
R6877:Fat3	UTSW	9	15,999,268 (GRCm38)	missense	probably benign
R6894:Fat3	UTSW	9	15,997,776 (GRCm38)	missense	probably damaging	1.00
R6915:Fat3	UTSW	9	16,377,748 (GRCm38)	missense	probably benign	0.37
R6931:Fat3	UTSW	9	15,959,942 (GRCm38)	missense	possibly damaging	0.89
R6934:Fat3	UTSW	9	16,376,956 (GRCm38)	missense	probably damaging	0.98
R6940:Fat3	UTSW	9	15,916,800 (GRCm38)	splice site	probably null
R6959:Fat3	UTSW	9	15,996,885 (GRCm38)	missense	possibly damaging	0.91
R6969:Fat3	UTSW	9	16,029,916 (GRCm38)	missense	probably benign	0.29
R6986:Fat3	UTSW	9	16,021,335 (GRCm38)	missense	probably damaging	1.00
R6993:Fat3	UTSW	9	15,919,221 (GRCm38)	missense	probably damaging	1.00
R7039:Fat3	UTSW	9	16,376,265 (GRCm38)	missense	probably damaging	1.00
R7051:Fat3	UTSW	9	16,377,827 (GRCm38)	missense	probably damaging	1.00
R7089:Fat3	UTSW	9	15,996,918 (GRCm38)	missense	probably benign	0.01
R7136:Fat3	UTSW	9	16,378,185 (GRCm38)	missense	probably benign
R7137:Fat3	UTSW	9	15,997,148 (GRCm38)	missense	probably damaging	1.00
R7154:Fat3	UTSW	9	15,996,864 (GRCm38)	missense	probably damaging	1.00
R7170:Fat3	UTSW	9	16,006,574 (GRCm38)	missense	probably damaging	0.99
R7183:Fat3	UTSW	9	15,922,837 (GRCm38)	missense	possibly damaging	0.81
R7237:Fat3	UTSW	9	16,377,214 (GRCm38)	missense	probably damaging	1.00
R7288:Fat3	UTSW	9	15,998,592 (GRCm38)	missense	probably damaging	1.00
R7293:Fat3	UTSW	9	15,915,296 (GRCm38)	missense
R7293:Fat3	UTSW	9	15,915,040 (GRCm38)	missense
R7381:Fat3	UTSW	9	16,246,987 (GRCm38)	missense	probably damaging	1.00
R7438:Fat3	UTSW	9	15,988,482 (GRCm38)	missense	probably benign
R7537:Fat3	UTSW	9	15,938,319 (GRCm38)	missense	probably damaging	1.00
R7560:Fat3	UTSW	9	15,996,842 (GRCm38)	missense	probably damaging	1.00
R7585:Fat3	UTSW	9	15,998,262 (GRCm38)	missense	probably benign	0.03
R7623:Fat3	UTSW	9	15,988,324 (GRCm38)	missense	probably damaging	1.00
R7624:Fat3	UTSW	9	15,959,869 (GRCm38)	missense	possibly damaging	0.72
R7684:Fat3	UTSW	9	15,988,268 (GRCm38)	critical splice donor site	probably null
R7690:Fat3	UTSW	9	15,998,181 (GRCm38)	missense	probably damaging	1.00
R7804:Fat3	UTSW	9	15,990,592 (GRCm38)	missense	probably benign	0.01
R7809:Fat3	UTSW	9	16,006,628 (GRCm38)	missense	probably damaging	1.00
R7924:Fat3	UTSW	9	15,999,297 (GRCm38)	missense	probably damaging	1.00
R7925:Fat3	UTSW	9	16,031,360 (GRCm38)	missense	possibly damaging	0.77
R7954:Fat3	UTSW	9	15,998,412 (GRCm38)	missense	probably damaging	1.00
R8021:Fat3	UTSW	9	15,999,109 (GRCm38)	missense	probably damaging	0.99
R8118:Fat3	UTSW	9	15,960,104 (GRCm38)	missense	probably benign
R8141:Fat3	UTSW	9	15,997,066 (GRCm38)	missense	possibly damaging	0.79
R8163:Fat3	UTSW	9	15,959,759 (GRCm38)	missense	probably damaging	1.00
R8170:Fat3	UTSW	9	15,947,496 (GRCm38)	missense	probably damaging	0.97
R8201:Fat3	UTSW	9	15,997,477 (GRCm38)	missense	possibly damaging	0.93
R8258:Fat3	UTSW	9	15,990,591 (GRCm38)	missense	possibly damaging	0.79
R8259:Fat3	UTSW	9	15,990,591 (GRCm38)	missense	possibly damaging	0.79
R8274:Fat3	UTSW	9	16,377,490 (GRCm38)	nonsense	probably null
R8275:Fat3	UTSW	9	16,246,750 (GRCm38)	missense	probably damaging	1.00
R8345:Fat3	UTSW	9	15,999,274 (GRCm38)	missense	probably benign	0.08
R8350:Fat3	UTSW	9	15,915,139 (GRCm38)	missense
R8405:Fat3	UTSW	9	15,995,871 (GRCm38)	missense	probably damaging	1.00
R8421:Fat3	UTSW	9	15,998,184 (GRCm38)	missense	probably damaging	1.00
R8450:Fat3	UTSW	9	15,915,139 (GRCm38)	missense
R8472:Fat3	UTSW	9	16,375,267 (GRCm38)	missense	possibly damaging	0.90
R8482:Fat3	UTSW	9	16,246,967 (GRCm38)	missense	probably benign	0.02
R8680:Fat3	UTSW	9	15,997,407 (GRCm38)	missense	probably damaging	0.99
R8690:Fat3	UTSW	9	15,967,101 (GRCm38)	missense	probably benign	0.45
R8748:Fat3	UTSW	9	15,922,865 (GRCm38)	missense	possibly damaging	0.70
R8756:Fat3	UTSW	9	16,376,589 (GRCm38)	missense	probably damaging	1.00
R8834:Fat3	UTSW	9	16,031,197 (GRCm38)	missense	probably damaging	1.00
R8848:Fat3	UTSW	9	15,967,102 (GRCm38)	missense	probably damaging	1.00
R8884:Fat3	UTSW	9	16,029,984 (GRCm38)	missense	probably damaging	1.00
R8898:Fat3	UTSW	9	15,947,526 (GRCm38)	missense	probably benign	0.04
R8930:Fat3	UTSW	9	15,999,523 (GRCm38)	missense	probably benign	0.06
R8932:Fat3	UTSW	9	15,999,523 (GRCm38)	missense	probably benign	0.06
R8954:Fat3	UTSW	9	16,376,568 (GRCm38)	missense	probably benign	0.00
R8995:Fat3	UTSW	9	16,375,602 (GRCm38)	missense	probably damaging	1.00
R9000:Fat3	UTSW	9	16,006,799 (GRCm38)	missense	probably benign	0.12
R9000:Fat3	UTSW	9	15,960,520 (GRCm38)	missense	possibly damaging	0.82
R9060:Fat3	UTSW	9	15,999,486 (GRCm38)	missense	possibly damaging	0.80
R9116:Fat3	UTSW	9	15,998,125 (GRCm38)	missense	probably benign	0.34
R9136:Fat3	UTSW	9	15,922,442 (GRCm38)	missense
R9193:Fat3	UTSW	9	15,998,952 (GRCm38)	missense	probably benign
R9235:Fat3	UTSW	9	15,922,378 (GRCm38)	missense	probably null
R9257:Fat3	UTSW	9	15,996,567 (GRCm38)	missense	probably benign
R9297:Fat3	UTSW	9	15,997,700 (GRCm38)	missense	probably damaging	1.00
R9307:Fat3	UTSW	9	16,021,423 (GRCm38)	missense	probably damaging	1.00
R9412:Fat3	UTSW	9	15,997,407 (GRCm38)	missense	probably damaging	0.99
R9427:Fat3	UTSW	9	16,377,395 (GRCm38)	nonsense	probably null
R9430:Fat3	UTSW	9	16,376,085 (GRCm38)	missense	probably damaging	1.00
R9480:Fat3	UTSW	9	16,031,407 (GRCm38)	missense	probably damaging	1.00
R9497:Fat3	UTSW	9	15,992,208 (GRCm38)	missense	probably damaging	0.99
R9547:Fat3	UTSW	9	15,999,846 (GRCm38)	missense	possibly damaging	0.86
R9569:Fat3	UTSW	9	15,919,199 (GRCm38)	missense
R9591:Fat3	UTSW	9	16,377,040 (GRCm38)	missense	probably benign	0.01
R9615:Fat3	UTSW	9	16,378,047 (GRCm38)	missense	probably benign	0.00
R9649:Fat3	UTSW	9	15,996,758 (GRCm38)	missense	possibly damaging	0.57
R9671:Fat3	UTSW	9	16,375,575 (GRCm38)	missense	possibly damaging	0.93
R9750:Fat3	UTSW	9	16,003,861 (GRCm38)	missense	probably benign	0.00
R9777:Fat3	UTSW	9	15,915,241 (GRCm38)	missense	probably benign
RF006:Fat3	UTSW	9	15,998,617 (GRCm38)	missense	probably benign	0.36
X0021:Fat3	UTSW	9	16,029,931 (GRCm38)	missense	probably null	0.66
X0026:Fat3	UTSW	9	15,996,333 (GRCm38)	missense	probably benign
X0064:Fat3	UTSW	9	15,919,277 (GRCm38)	missense	probably benign
Z1176:Fat3	UTSW	9	16,375,617 (GRCm38)	missense	probably benign
Z1176:Fat3	UTSW	9	16,375,429 (GRCm38)	missense	probably damaging	1.00
Z1176:Fat3	UTSW	9	15,947,526 (GRCm38)	missense	probably damaging	0.98
Z1177:Fat3	UTSW	9	15,965,991 (GRCm38)	missense	possibly damaging	0.68
Z1177:Fat3	UTSW	9	15,947,538 (GRCm38)	missense	probably damaging	1.00
Z1177:Fat3	UTSW	9	15,923,026 (GRCm38)	missense	possibly damaging	0.81
Z1177:Fat3	UTSW	9	15,969,835 (GRCm38)	missense	probably damaging	0.99

Predicted Primers

PCR Primer
(F):5'- CCGTGTTCTCATAGACACATGC -3'
(R):5'- AGCAGTTGTTTTGCCATTGC -3'

Sequencing Primer
(F):5'- CACATGCAGTGTAGTGGTTGGAAG -3'
(R):5'- GCCATTGCATCTAAAATTCTGTG -3'

Posted On

2017-08-16