Mutagenetix > Incidental Mutation

Incidental Mutation 'R5564:Dnah3'

486844

Institutional Source

Beutler Lab

Gene Symbol

Dnah3

Ensembl Gene

ENSMUSG00000052273

Gene Name

dynein, axonemal, heavy chain 3

Synonyms

Dnahc3

MMRRC Submission

043121-MU

Accession Numbers

Essential gene?

Probably non essential (E-score: 0.099) question?

Stock #

R5564 (G1)

Quality Score

225

Status

Validated

Chromosome

Chromosomal Location

119521894-119694503 bp(-) (GRCm39)

Type of Mutation

critical splice donor site (1 bp from exon)

DNA Base Change (assembly)

C to A at 119570689 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Ref Sequence

ENSEMBL: ENSMUSP00000146895 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000046993] [ENSMUST00000046993] [ENSMUST00000209154] [ENSMUST00000209154] [ENSMUST00000213149]

AlphaFold

no structure available at present

Predicted Effect

probably null
Transcript: ENSMUST00000046993

SMART Domains

Protein: ENSMUSP00000042857
Gene: ENSMUSG00000052273

Domain	Start	End	E-Value	Type
low complexity region	121	133	N/A	INTRINSIC
low complexity region	805	820	N/A	INTRINSIC
Pfam:DHC_N2	826	1235	3.3e-144	PFAM
AAA	1388	1527	1.59e-1	SMART
low complexity region	1594	1606	N/A	INTRINSIC
Blast:AAA	1669	1897	9e-84	BLAST
AAA	2033	2180	1.33e-3	SMART
Pfam:AAA_8	2362	2632	1.5e-63	PFAM
Pfam:MT	2644	2994	7.4e-52	PFAM
Pfam:AAA_9	3015	3240	3.5e-92	PFAM
low complexity region	3338	3349	N/A	INTRINSIC
Pfam:Dynein_heavy	3376	4079	4.4e-285	PFAM

Predicted Effect

probably null
Transcript: ENSMUST00000046993

SMART Domains

Protein: ENSMUSP00000042857
Gene: ENSMUSG00000052273

Domain	Start	End	E-Value	Type
low complexity region	121	133	N/A	INTRINSIC
low complexity region	805	820	N/A	INTRINSIC
Pfam:DHC_N2	826	1235	3.3e-144	PFAM
AAA	1388	1527	1.59e-1	SMART
low complexity region	1594	1606	N/A	INTRINSIC
Blast:AAA	1669	1897	9e-84	BLAST
AAA	2033	2180	1.33e-3	SMART
Pfam:AAA_8	2362	2632	1.5e-63	PFAM
Pfam:MT	2644	2994	7.4e-52	PFAM
Pfam:AAA_9	3015	3240	3.5e-92	PFAM
low complexity region	3338	3349	N/A	INTRINSIC
Pfam:Dynein_heavy	3376	4079	4.4e-285	PFAM

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000157547

Predicted Effect

probably benign
Transcript: ENSMUST00000208910

Predicted Effect

probably null
Transcript: ENSMUST00000209154

Predicted Effect

probably null
Transcript: ENSMUST00000209154

Predicted Effect

probably benign
Transcript: ENSMUST00000213149

Meta Mutation Damage Score

0.9489

Coding Region Coverage

1x: 99.9%
3x: 99.7%
10x: 98.7%
20x: 96.5%

Validation Efficiency

98% (57/58)

MGI Phenotype

FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene belongs to the dynein family, whose members encode large proteins that are constituents of the microtubule-associated motor protein complex. This complex is composed of dynein heavy, intermediate and light chains, which can be axonemal or cytoplasmic. This protein is an axonemal dynein heavy chain. It is involved in producing force for ciliary beating by using energy from ATP hydrolysis. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Dec 2016]

Allele List at MGI

Other mutations in this stock

Total: 52 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
Aadacl2fm2	T	C	3: 59,659,513 (GRCm39)	V322A	probably benign	Het
Abca8b	G	T	11: 109,825,407 (GRCm39)	L1598M	probably benign	Het
Adam4	T	C	12: 81,466,348 (GRCm39)	T758A	probably benign	Het
B3galnt2	T	C	13: 14,169,814 (GRCm39)	I424T	probably damaging	Het
Cacna1g	T	C	11: 94,321,312 (GRCm39)	Y1316C	probably damaging	Het
Cacna2d1	T	C	5: 16,517,517 (GRCm39)	S388P	probably damaging	Het
Ccdc157	A	G	11: 4,098,765 (GRCm39)	L247S	probably damaging	Het
Cdh8	A	G	8: 99,757,498 (GRCm39)	I700T	possibly damaging	Het
Cdhr3	G	T	12: 33,098,985 (GRCm39)	Y535*	probably null	Het
Clasp2	T	C	9: 113,641,836 (GRCm39)		probably null	Het
Col16a1	T	A	4: 129,947,151 (GRCm39)	D165E	probably damaging	Het
Col9a1	A	T	1: 24,234,436 (GRCm39)		probably benign	Het
Cpa3	A	T	3: 20,296,307 (GRCm39)	I10N	possibly damaging	Het
Cstf3	T	A	2: 104,439,347 (GRCm39)		probably benign	Het
E2f6	T	C	12: 16,874,706 (GRCm39)	C263R	probably benign	Het
Eps8l2	C	A	7: 140,936,534 (GRCm39)	Q288K	possibly damaging	Het
Fam193a	T	A	5: 34,578,199 (GRCm39)	V231D	probably damaging	Het
Gjd3	C	T	11: 102,691,029 (GRCm39)	G325S	probably benign	Het
Gpatch8	T	A	11: 102,429,111 (GRCm39)	E39D	unknown	Het
Gpr107	C	T	2: 31,042,375 (GRCm39)	A2V	probably damaging	Het
Kansl3	G	T	1: 36,385,045 (GRCm39)	H629N	possibly damaging	Het
Kcna10	C	A	3: 107,101,545 (GRCm39)	H59N	probably benign	Het
Kitl	A	T	10: 99,915,886 (GRCm39)	E138D	possibly damaging	Het
Kpna2	T	C	11: 106,881,571 (GRCm39)	K353R	probably damaging	Het
M1ap	T	A	6: 82,958,798 (GRCm39)	I143N	probably damaging	Het
Macf1	A	G	4: 123,420,538 (GRCm39)	S239P	possibly damaging	Het
Med13l	T	A	5: 118,880,105 (GRCm39)	S1066T	probably damaging	Het
Mettl23	G	T	11: 116,739,865 (GRCm39)	E47*	probably null	Het
Or52i2	T	C	7: 102,319,433 (GRCm39)	F102S	probably damaging	Het
Or5af1	C	T	11: 58,722,039 (GRCm39)	Q20*	probably null	Het
Proca1	T	A	11: 78,092,699 (GRCm39)	D48E	possibly damaging	Het
Rab34	T	G	11: 78,082,458 (GRCm39)	V227G	probably damaging	Het
Rab7	A	T	6: 87,990,632 (GRCm39)	L14Q	probably damaging	Het
Rasgef1c	C	T	11: 49,847,934 (GRCm39)	S23F	probably benign	Het
Rit1	A	G	3: 88,633,457 (GRCm39)		probably benign	Het
Scin	T	C	12: 40,174,568 (GRCm39)	T172A	probably benign	Het
Scmh1	C	A	4: 120,325,575 (GRCm39)	N97K	probably damaging	Het
Skint6	T	C	4: 112,846,162 (GRCm39)	E655G	possibly damaging	Het
Slc22a15	A	G	3: 101,771,905 (GRCm39)	V243A	probably benign	Het
Smg1	A	G	7: 117,789,042 (GRCm39)		probably benign	Het
Smim7	C	T	8: 73,324,867 (GRCm39)	G3R	probably damaging	Het
Snurf	C	T	7: 59,645,282 (GRCm39)	R44H	possibly damaging	Het
Snx13	G	A	12: 35,174,471 (GRCm39)	A667T	possibly damaging	Het
Sowaha	T	G	11: 53,369,590 (GRCm39)	H382P	probably damaging	Het
Tbc1d2	C	T	4: 46,629,912 (GRCm39)	G252R	probably benign	Het
Tmem259	G	T	10: 79,814,442 (GRCm39)		probably null	Het
Topbp1	A	G	9: 103,211,277 (GRCm39)	T945A	probably damaging	Het
Tor1aip2	T	C	1: 155,939,307 (GRCm39)		probably benign	Het
Ube3b	T	C	5: 114,527,136 (GRCm39)	V118A	probably damaging	Het
Usp38	T	C	8: 81,711,717 (GRCm39)	K773E	probably damaging	Het
Wnk1	G	A	6: 119,925,852 (GRCm39)		probably benign	Het
Zfp871	A	G	17: 32,994,842 (GRCm39)	V111A	possibly damaging	Het

Other mutations in Dnah3

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00650:Dnah3	APN	7	119,538,128 (GRCm39)	missense	possibly damaging	0.88
IGL01095:Dnah3	APN	7	119,550,820 (GRCm39)	missense	probably benign	0.02
IGL01329:Dnah3	APN	7	119,622,164 (GRCm39)	missense	probably damaging	1.00
IGL01380:Dnah3	APN	7	119,525,787 (GRCm39)	missense	probably damaging	1.00
IGL01410:Dnah3	APN	7	119,566,943 (GRCm39)	missense	possibly damaging	0.91
IGL01487:Dnah3	APN	7	119,564,753 (GRCm39)	nonsense	probably null
IGL01843:Dnah3	APN	7	119,542,798 (GRCm39)	missense	probably benign	0.12
IGL01929:Dnah3	APN	7	119,550,874 (GRCm39)	nonsense	probably null
IGL01994:Dnah3	APN	7	119,550,437 (GRCm39)	missense	possibly damaging	0.58
IGL02115:Dnah3	APN	7	119,628,277 (GRCm39)	missense	probably damaging	1.00
IGL02273:Dnah3	APN	7	119,550,494 (GRCm39)	missense	probably damaging	1.00
IGL02299:Dnah3	APN	7	119,566,802 (GRCm39)	missense	probably benign	0.39
IGL02421:Dnah3	APN	7	119,550,215 (GRCm39)	missense	possibly damaging	0.87
IGL02514:Dnah3	APN	7	119,565,470 (GRCm39)	missense	probably damaging	1.00
IGL02596:Dnah3	APN	7	119,538,137 (GRCm39)	missense	probably benign	0.19
IGL02716:Dnah3	APN	7	119,536,246 (GRCm39)	missense	probably damaging	0.97
IGL02738:Dnah3	APN	7	119,564,720 (GRCm39)	missense	probably benign
IGL03404:Dnah3	APN	7	119,538,200 (GRCm39)	missense	probably damaging	1.00
R0964_Dnah3_480	UTSW	7	119,551,962 (GRCm39)	splice site	probably benign
R1778_Dnah3_238	UTSW	7	119,677,625 (GRCm39)	missense	probably damaging	1.00
R4658_Dnah3_599	UTSW	7	119,549,874 (GRCm39)	missense	probably damaging	1.00
BB004:Dnah3	UTSW	7	119,550,494 (GRCm39)	missense	probably damaging	0.97
BB014:Dnah3	UTSW	7	119,550,494 (GRCm39)	missense	probably damaging	0.97
R0011:Dnah3	UTSW	7	119,618,924 (GRCm39)	missense	probably damaging	1.00
R0195:Dnah3	UTSW	7	119,676,998 (GRCm39)	critical splice donor site	probably null
R0241:Dnah3	UTSW	7	119,521,953 (GRCm39)	missense	probably damaging	1.00
R0241:Dnah3	UTSW	7	119,521,953 (GRCm39)	missense	probably damaging	1.00
R0312:Dnah3	UTSW	7	119,644,882 (GRCm39)	missense	probably damaging	1.00
R0316:Dnah3	UTSW	7	119,564,882 (GRCm39)	missense	possibly damaging	0.94
R0370:Dnah3	UTSW	7	119,685,943 (GRCm39)	missense	possibly damaging	0.91
R0426:Dnah3	UTSW	7	119,542,795 (GRCm39)	missense	probably benign	0.11
R0525:Dnah3	UTSW	7	119,527,977 (GRCm39)	missense	probably damaging	1.00
R0625:Dnah3	UTSW	7	119,671,110 (GRCm39)	missense	possibly damaging	0.68
R0627:Dnah3	UTSW	7	119,620,138 (GRCm39)	missense	probably damaging	1.00
R0632:Dnah3	UTSW	7	119,567,128 (GRCm39)	missense	probably benign	0.11
R0928:Dnah3	UTSW	7	119,629,274 (GRCm39)	missense	probably damaging	1.00
R0964:Dnah3	UTSW	7	119,551,962 (GRCm39)	splice site	probably benign
R0972:Dnah3	UTSW	7	119,634,563 (GRCm39)	splice site	probably null
R1066:Dnah3	UTSW	7	119,660,232 (GRCm39)	missense	probably damaging	1.00
R1082:Dnah3	UTSW	7	119,677,668 (GRCm39)	missense	probably damaging	1.00
R1127:Dnah3	UTSW	7	119,522,253 (GRCm39)	missense	probably damaging	1.00
R1132:Dnah3	UTSW	7	119,538,227 (GRCm39)	missense	possibly damaging	0.50
R1222:Dnah3	UTSW	7	119,689,899 (GRCm39)	missense	probably benign	0.28
R1420:Dnah3	UTSW	7	119,551,202 (GRCm39)	missense	probably damaging	0.99
R1456:Dnah3	UTSW	7	119,646,853 (GRCm39)	missense	probably damaging	1.00
R1472:Dnah3	UTSW	7	119,670,181 (GRCm39)	missense	probably benign	0.12
R1617:Dnah3	UTSW	7	119,689,169 (GRCm39)	missense	probably benign	0.01
R1624:Dnah3	UTSW	7	119,618,918 (GRCm39)	missense	probably damaging	0.99
R1654:Dnah3	UTSW	7	119,525,672 (GRCm39)	missense	probably damaging	1.00
R1673:Dnah3	UTSW	7	119,570,402 (GRCm39)	nonsense	probably null
R1677:Dnah3	UTSW	7	119,527,963 (GRCm39)	missense	probably damaging	1.00
R1687:Dnah3	UTSW	7	119,645,009 (GRCm39)	splice site	probably null
R1711:Dnah3	UTSW	7	119,677,794 (GRCm39)	missense	probably damaging	1.00
R1738:Dnah3	UTSW	7	119,634,582 (GRCm39)	missense	probably damaging	1.00
R1778:Dnah3	UTSW	7	119,677,625 (GRCm39)	missense	probably damaging	1.00
R1866:Dnah3	UTSW	7	119,528,079 (GRCm39)	splice site	probably null
R1883:Dnah3	UTSW	7	119,677,142 (GRCm39)	missense	probably benign	0.06
R1894:Dnah3	UTSW	7	119,685,557 (GRCm39)	missense	probably benign	0.05
R1929:Dnah3	UTSW	7	119,574,352 (GRCm39)	missense	probably benign	0.10
R1988:Dnah3	UTSW	7	119,567,182 (GRCm39)	missense	probably damaging	0.99
R1988:Dnah3	UTSW	7	119,566,793 (GRCm39)	missense	possibly damaging	0.92
R2010:Dnah3	UTSW	7	119,694,400 (GRCm39)	start codon destroyed	probably benign	0.00
R2022:Dnah3	UTSW	7	119,550,465 (GRCm39)	missense	probably damaging	1.00
R2026:Dnah3	UTSW	7	119,638,629 (GRCm39)	missense	probably damaging	1.00
R2063:Dnah3	UTSW	7	119,551,132 (GRCm39)	missense	probably damaging	0.96
R2131:Dnah3	UTSW	7	119,566,982 (GRCm39)	missense	possibly damaging	0.93
R2152:Dnah3	UTSW	7	119,551,236 (GRCm39)	missense	probably benign	0.02
R2199:Dnah3	UTSW	7	119,550,792 (GRCm39)	missense	possibly damaging	0.89
R2271:Dnah3	UTSW	7	119,574,352 (GRCm39)	missense	probably benign	0.10
R2350:Dnah3	UTSW	7	119,645,011 (GRCm39)	splice site	probably null
R2567:Dnah3	UTSW	7	119,551,920 (GRCm39)	missense	possibly damaging	0.83
R2848:Dnah3	UTSW	7	119,567,161 (GRCm39)	missense	probably benign	0.01
R2902:Dnah3	UTSW	7	119,550,722 (GRCm39)	missense	possibly damaging	0.61
R2926:Dnah3	UTSW	7	119,550,338 (GRCm39)	missense	probably damaging	1.00
R2944:Dnah3	UTSW	7	119,550,333 (GRCm39)	missense	probably damaging	1.00
R3022:Dnah3	UTSW	7	119,677,704 (GRCm39)	missense	possibly damaging	0.93
R3401:Dnah3	UTSW	7	119,566,879 (GRCm39)	missense	probably benign	0.00
R3402:Dnah3	UTSW	7	119,566,879 (GRCm39)	missense	probably benign	0.00
R3403:Dnah3	UTSW	7	119,566,879 (GRCm39)	missense	probably benign	0.00
R3919:Dnah3	UTSW	7	119,550,303 (GRCm39)	missense	probably damaging	1.00
R3972:Dnah3	UTSW	7	119,685,943 (GRCm39)	missense	probably damaging	0.99
R4162:Dnah3	UTSW	7	119,522,061 (GRCm39)	missense	probably damaging	1.00
R4184:Dnah3	UTSW	7	119,682,516 (GRCm39)	missense	probably damaging	1.00
R4198:Dnah3	UTSW	7	119,522,061 (GRCm39)	missense	probably damaging	1.00
R4199:Dnah3	UTSW	7	119,522,061 (GRCm39)	missense	probably damaging	1.00
R4200:Dnah3	UTSW	7	119,522,061 (GRCm39)	missense	probably damaging	1.00
R4239:Dnah3	UTSW	7	119,628,248 (GRCm39)	nonsense	probably null
R4478:Dnah3	UTSW	7	119,671,086 (GRCm39)	missense	probably benign	0.00
R4579:Dnah3	UTSW	7	119,608,554 (GRCm39)	missense	probably damaging	1.00
R4600:Dnah3	UTSW	7	119,689,169 (GRCm39)	missense	probably benign
R4649:Dnah3	UTSW	7	119,646,921 (GRCm39)	missense	probably damaging	1.00
R4658:Dnah3	UTSW	7	119,549,874 (GRCm39)	missense	probably damaging	1.00
R4728:Dnah3	UTSW	7	119,658,589 (GRCm39)	missense	probably damaging	0.99
R4739:Dnah3	UTSW	7	119,677,169 (GRCm39)	missense	possibly damaging	0.54
R4758:Dnah3	UTSW	7	119,678,629 (GRCm39)	missense	probably benign	0.00
R4785:Dnah3	UTSW	7	119,567,047 (GRCm39)	missense	probably benign	0.29
R4789:Dnah3	UTSW	7	119,610,295 (GRCm39)	missense	probably damaging	1.00
R4930:Dnah3	UTSW	7	119,550,904 (GRCm39)	nonsense	probably null
R4935:Dnah3	UTSW	7	119,615,700 (GRCm39)	nonsense	probably null
R4946:Dnah3	UTSW	7	119,530,783 (GRCm39)	missense	probably damaging	1.00
R4981:Dnah3	UTSW	7	119,555,424 (GRCm39)	missense	probably benign	0.03
R4984:Dnah3	UTSW	7	119,528,002 (GRCm39)	missense	probably benign	0.04
R5025:Dnah3	UTSW	7	119,671,128 (GRCm39)	missense	probably benign	0.02
R5046:Dnah3	UTSW	7	119,550,803 (GRCm39)	missense	probably damaging	1.00
R5056:Dnah3	UTSW	7	119,620,169 (GRCm39)	missense	probably damaging	1.00
R5068:Dnah3	UTSW	7	119,632,013 (GRCm39)	missense	probably benign
R5069:Dnah3	UTSW	7	119,632,013 (GRCm39)	missense	probably benign
R5154:Dnah3	UTSW	7	119,551,642 (GRCm39)	missense	probably damaging	1.00
R5208:Dnah3	UTSW	7	119,631,861 (GRCm39)	missense	probably damaging	1.00
R5323:Dnah3	UTSW	7	119,620,234 (GRCm39)	missense	probably damaging	1.00
R5330:Dnah3	UTSW	7	119,542,871 (GRCm39)	missense	probably benign	0.00
R5385:Dnah3	UTSW	7	119,524,126 (GRCm39)	missense	probably damaging	1.00
R5391:Dnah3	UTSW	7	119,689,299 (GRCm39)	missense	probably benign	0.02
R5594:Dnah3	UTSW	7	119,570,844 (GRCm39)	missense	possibly damaging	0.89
R5610:Dnah3	UTSW	7	119,538,288 (GRCm39)	splice site	probably null
R5673:Dnah3	UTSW	7	119,550,812 (GRCm39)	missense	possibly damaging	0.91
R5678:Dnah3	UTSW	7	119,677,074 (GRCm39)	missense	probably benign	0.00
R5737:Dnah3	UTSW	7	119,658,421 (GRCm39)	missense	probably benign	0.03
R5766:Dnah3	UTSW	7	119,577,445 (GRCm39)	missense	probably damaging	1.00
R5769:Dnah3	UTSW	7	119,689,175 (GRCm39)	nonsense	probably null
R5789:Dnah3	UTSW	7	119,542,822 (GRCm39)	missense	possibly damaging	0.70
R5791:Dnah3	UTSW	7	119,530,696 (GRCm39)	missense	probably benign	0.00
R5841:Dnah3	UTSW	7	119,550,244 (GRCm39)	utr 3 prime	probably benign
R5843:Dnah3	UTSW	7	119,550,244 (GRCm39)	utr 3 prime	probably benign
R5844:Dnah3	UTSW	7	119,550,244 (GRCm39)	utr 3 prime	probably benign
R5846:Dnah3	UTSW	7	119,550,244 (GRCm39)	utr 3 prime	probably benign
R5851:Dnah3	UTSW	7	119,638,585 (GRCm39)	missense	possibly damaging	0.51
R5853:Dnah3	UTSW	7	119,538,056 (GRCm39)	missense	probably damaging	1.00
R5857:Dnah3	UTSW	7	119,550,244 (GRCm39)	utr 3 prime	probably benign
R5865:Dnah3	UTSW	7	119,574,331 (GRCm39)	missense	probably benign	0.00
R5885:Dnah3	UTSW	7	119,668,927 (GRCm39)	missense	probably benign	0.10
R5898:Dnah3	UTSW	7	119,677,724 (GRCm39)	missense	probably benign	0.37
R5917:Dnah3	UTSW	7	119,615,749 (GRCm39)	missense	probably damaging	1.00
R5964:Dnah3	UTSW	7	119,522,103 (GRCm39)	missense	probably benign	0.00
R5990:Dnah3	UTSW	7	119,672,764 (GRCm39)	missense	probably benign
R6004:Dnah3	UTSW	7	119,685,520 (GRCm39)	missense	probably benign	0.10
R6033:Dnah3	UTSW	7	119,670,870 (GRCm39)	missense	probably benign	0.00
R6033:Dnah3	UTSW	7	119,670,870 (GRCm39)	missense	probably benign	0.00
R6045:Dnah3	UTSW	7	119,566,745 (GRCm39)	missense	probably damaging	0.99
R6056:Dnah3	UTSW	7	119,629,254 (GRCm39)	missense	probably damaging	1.00
R6133:Dnah3	UTSW	7	119,685,469 (GRCm39)	missense	probably benign	0.10
R6229:Dnah3	UTSW	7	119,564,711 (GRCm39)	missense	probably benign	0.11
R6237:Dnah3	UTSW	7	119,608,607 (GRCm39)	missense	probably damaging	1.00
R6333:Dnah3	UTSW	7	119,653,856 (GRCm39)	missense	probably damaging	1.00
R6408:Dnah3	UTSW	7	119,522,191 (GRCm39)	splice site	probably null
R6447:Dnah3	UTSW	7	119,522,277 (GRCm39)	missense	probably benign	0.12
R6606:Dnah3	UTSW	7	119,660,179 (GRCm39)	missense	probably benign	0.02
R6666:Dnah3	UTSW	7	119,670,172 (GRCm39)	missense	probably benign	0.16
R6733:Dnah3	UTSW	7	119,522,197 (GRCm39)	missense	probably benign	0.22
R6815:Dnah3	UTSW	7	119,570,950 (GRCm39)	missense	probably benign
R6882:Dnah3	UTSW	7	119,570,407 (GRCm39)	missense	possibly damaging	0.95
R6934:Dnah3	UTSW	7	119,653,824 (GRCm39)	critical splice donor site	probably null
R6966:Dnah3	UTSW	7	119,631,977 (GRCm39)	missense	probably damaging	1.00
R7025:Dnah3	UTSW	7	119,629,233 (GRCm39)	missense	possibly damaging	0.90
R7207:Dnah3	UTSW	7	119,570,312 (GRCm39)	missense	probably damaging	1.00
R7214:Dnah3	UTSW	7	119,521,965 (GRCm39)	missense	probably damaging	1.00
R7222:Dnah3	UTSW	7	119,670,746 (GRCm39)	missense	probably benign	0.00
R7235:Dnah3	UTSW	7	119,631,893 (GRCm39)	missense	probably damaging	1.00
R7241:Dnah3	UTSW	7	119,542,856 (GRCm39)	missense	probably benign	0.03
R7313:Dnah3	UTSW	7	119,580,567 (GRCm39)	missense	probably benign	0.39
R7342:Dnah3	UTSW	7	119,629,208 (GRCm39)	missense	probably damaging	1.00
R7368:Dnah3	UTSW	7	119,628,239 (GRCm39)	missense	probably benign
R7375:Dnah3	UTSW	7	119,550,900 (GRCm39)	missense	probably damaging	1.00
R7395:Dnah3	UTSW	7	119,660,183 (GRCm39)	missense	probably benign	0.00
R7395:Dnah3	UTSW	7	119,565,474 (GRCm39)	missense
R7431:Dnah3	UTSW	7	119,650,967 (GRCm39)	missense	probably damaging	1.00
R7499:Dnah3	UTSW	7	119,660,135 (GRCm39)	missense	probably damaging	0.99
R7515:Dnah3	UTSW	7	119,672,815 (GRCm39)	missense	probably benign	0.21
R7564:Dnah3	UTSW	7	119,570,817 (GRCm39)	missense	probably benign
R7618:Dnah3	UTSW	7	119,577,601 (GRCm39)	missense	probably damaging	0.97
R7697:Dnah3	UTSW	7	119,566,657 (GRCm39)	missense
R7728:Dnah3	UTSW	7	119,538,051 (GRCm39)	missense	probably damaging	1.00
R7757:Dnah3	UTSW	7	119,570,438 (GRCm39)	splice site	probably null
R7757:Dnah3	UTSW	7	119,670,793 (GRCm39)	missense	probably benign
R7774:Dnah3	UTSW	7	119,550,975 (GRCm39)	nonsense	probably null
R7804:Dnah3	UTSW	7	119,610,235 (GRCm39)	missense	probably damaging	1.00
R7804:Dnah3	UTSW	7	119,551,841 (GRCm39)	missense	probably damaging	1.00
R7857:Dnah3	UTSW	7	119,550,927 (GRCm39)	missense	probably damaging	1.00
R7871:Dnah3	UTSW	7	119,566,775 (GRCm39)	missense
R7903:Dnah3	UTSW	7	119,641,351 (GRCm39)	missense	probably damaging	1.00
R7927:Dnah3	UTSW	7	119,550,494 (GRCm39)	missense	probably damaging	0.97
R7989:Dnah3	UTSW	7	119,677,012 (GRCm39)	missense	probably benign
R8142:Dnah3	UTSW	7	119,660,189 (GRCm39)	missense	probably benign	0.00
R8164:Dnah3	UTSW	7	119,566,837 (GRCm39)	missense	probably damaging	1.00
R8237:Dnah3	UTSW	7	119,525,636 (GRCm39)	missense	probably benign	0.01
R8313:Dnah3	UTSW	7	119,550,375 (GRCm39)	missense	probably benign	0.38
R8338:Dnah3	UTSW	7	119,671,104 (GRCm39)	missense	probably benign	0.01
R8355:Dnah3	UTSW	7	119,551,431 (GRCm39)	missense	probably damaging	1.00
R8408:Dnah3	UTSW	7	119,551,728 (GRCm39)	missense	probably damaging	1.00
R8411:Dnah3	UTSW	7	119,610,253 (GRCm39)	missense	probably damaging	1.00
R8455:Dnah3	UTSW	7	119,551,431 (GRCm39)	missense	probably damaging	1.00
R8483:Dnah3	UTSW	7	119,536,253 (GRCm39)	missense	probably benign	0.00
R8531:Dnah3	UTSW	7	119,550,591 (GRCm39)	missense	probably damaging	1.00
R8885:Dnah3	UTSW	7	119,561,375 (GRCm39)	missense
R8912:Dnah3	UTSW	7	119,689,869 (GRCm39)	missense	probably benign	0.06
R8966:Dnah3	UTSW	7	119,549,881 (GRCm39)	nonsense	probably null
R8982:Dnah3	UTSW	7	119,536,294 (GRCm39)	missense	probably damaging	1.00
R9043:Dnah3	UTSW	7	119,551,272 (GRCm39)	missense	probably benign
R9053:Dnah3	UTSW	7	119,618,987 (GRCm39)	missense	possibly damaging	0.67
R9059:Dnah3	UTSW	7	119,684,368 (GRCm39)	missense	probably benign	0.01
R9182:Dnah3	UTSW	7	119,684,351 (GRCm39)	missense	probably damaging	0.98
R9365:Dnah3	UTSW	7	119,566,859 (GRCm39)	missense
R9383:Dnah3	UTSW	7	119,646,819 (GRCm39)	missense	probably benign	0.23
R9430:Dnah3	UTSW	7	119,628,205 (GRCm39)	missense	probably damaging	1.00
R9449:Dnah3	UTSW	7	119,551,473 (GRCm39)	missense	probably benign	0.12
R9462:Dnah3	UTSW	7	119,551,523 (GRCm39)	missense	probably benign	0.05
R9505:Dnah3	UTSW	7	119,644,912 (GRCm39)	missense	probably damaging	1.00
R9559:Dnah3	UTSW	7	119,650,951 (GRCm39)	missense	probably benign	0.07
R9562:Dnah3	UTSW	7	119,610,114 (GRCm39)	missense	probably benign	0.05
R9565:Dnah3	UTSW	7	119,610,114 (GRCm39)	missense	probably benign	0.05
R9609:Dnah3	UTSW	7	119,670,236 (GRCm39)	missense	probably damaging	0.98
R9622:Dnah3	UTSW	7	119,561,356 (GRCm39)	missense
R9633:Dnah3	UTSW	7	119,550,216 (GRCm39)	missense	probably benign
R9654:Dnah3	UTSW	7	119,641,396 (GRCm39)	nonsense	probably null
R9665:Dnah3	UTSW	7	119,644,981 (GRCm39)	missense	probably benign	0.01
R9681:Dnah3	UTSW	7	119,677,611 (GRCm39)	missense	probably benign	0.04
R9717:Dnah3	UTSW	7	119,574,299 (GRCm39)	missense	probably damaging	1.00
Z1088:Dnah3	UTSW	7	119,610,096 (GRCm39)	missense	probably null	1.00
Z1088:Dnah3	UTSW	7	119,685,520 (GRCm39)	missense	probably benign	0.00
Z1176:Dnah3	UTSW	7	119,567,026 (GRCm39)	missense
Z1177:Dnah3	UTSW	7	119,607,085 (GRCm39)	missense	probably benign
Z1177:Dnah3	UTSW	7	119,567,124 (GRCm39)	missense	probably damaging	0.99

Predicted Primers

PCR Primer
(F):5'- TGTGATGACAGTTCTCAAGAAGTCTC -3'
(R):5'- ATGTGACTGATCTGCCTCCC -3'

Sequencing Primer
(F):5'- CAAGAAGTCTCTAAATCTTAGGGTCG -3'
(R):5'- CCTATTCCTCCTGAGGTATGGG -3'

Posted On

2017-08-28