Incidental Mutation 'R0523:Myocd'
| ID |
48728 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Myocd
|
| Ensembl Gene |
ENSMUSG00000020542 |
| Gene Name |
myocardin |
| Synonyms |
Srfcp |
| MMRRC Submission |
038716-MU
|
| Accession Numbers |
|
| Essential gene? |
Essential
(E-score: 1.000)
|
| Stock # |
R0523 (G1)
|
| Quality Score |
216 |
|
Status
|
Not validated
|
| Chromosome |
11 |
| Chromosomal Location |
65067387-65160815 bp(-) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
A to G
at 65071728 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Valine to Alanine
at position 740
(V740A)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000099695
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000101042]
[ENSMUST00000102635]
[ENSMUST00000108695]
|
| AlphaFold |
Q8VIM5 |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000101042
AA Change: V660A
PolyPhen 2
Score 0.011 (Sensitivity: 0.96; Specificity: 0.78)
|
| SMART Domains |
Protein: ENSMUSP00000098603
Gene: ENSMUSG00000020542
AA Change: V660A
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
19 |
32 |
N/A |
INTRINSIC |
|
low complexity region
|
119 |
132 |
N/A |
INTRINSIC |
|
SCOP:d1lsha3
|
140 |
221 |
4e-3 |
SMART |
|
SAP
|
252 |
286 |
1.29e-8 |
SMART |
|
low complexity region
|
326 |
343 |
N/A |
INTRINSIC |
|
low complexity region
|
371 |
383 |
N/A |
INTRINSIC |
|
coiled coil region
|
396 |
435 |
N/A |
INTRINSIC |
|
low complexity region
|
557 |
573 |
N/A |
INTRINSIC |
|
low complexity region
|
615 |
629 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000102635
AA Change: V740A
PolyPhen 2
Score 0.999 (Sensitivity: 0.14; Specificity: 0.99)
|
| SMART Domains |
Protein: ENSMUSP00000099695
Gene: ENSMUSG00000020542
AA Change: V740A
| Domain | Start | End | E-Value | Type |
|---|
|
RPEL
|
18 |
43 |
4e-1 |
SMART |
|
RPEL
|
62 |
87 |
9.26e0 |
SMART |
|
RPEL
|
106 |
131 |
1.15e-6 |
SMART |
|
low complexity region
|
147 |
160 |
N/A |
INTRINSIC |
|
low complexity region
|
247 |
260 |
N/A |
INTRINSIC |
|
SCOP:d1lsha3
|
268 |
349 |
4e-3 |
SMART |
|
SAP
|
380 |
414 |
1.29e-8 |
SMART |
|
low complexity region
|
454 |
471 |
N/A |
INTRINSIC |
|
low complexity region
|
499 |
511 |
N/A |
INTRINSIC |
|
coiled coil region
|
524 |
563 |
N/A |
INTRINSIC |
|
low complexity region
|
695 |
709 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000108695
AA Change: V788A
PolyPhen 2
Score 0.996 (Sensitivity: 0.55; Specificity: 0.98)
|
| SMART Domains |
Protein: ENSMUSP00000104335
Gene: ENSMUSG00000020542
AA Change: V788A
| Domain | Start | End | E-Value | Type |
|---|
|
RPEL
|
18 |
43 |
4e-1 |
SMART |
|
RPEL
|
62 |
87 |
9.26e0 |
SMART |
|
RPEL
|
106 |
131 |
1.15e-6 |
SMART |
|
low complexity region
|
147 |
160 |
N/A |
INTRINSIC |
|
low complexity region
|
247 |
260 |
N/A |
INTRINSIC |
|
SCOP:d1lsha3
|
268 |
349 |
5e-3 |
SMART |
|
SAP
|
380 |
414 |
1.29e-8 |
SMART |
|
low complexity region
|
454 |
471 |
N/A |
INTRINSIC |
|
low complexity region
|
499 |
511 |
N/A |
INTRINSIC |
|
coiled coil region
|
524 |
563 |
N/A |
INTRINSIC |
|
low complexity region
|
685 |
701 |
N/A |
INTRINSIC |
|
low complexity region
|
743 |
757 |
N/A |
INTRINSIC |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000151483
|
| Coding Region Coverage |
- 1x: 99.2%
- 3x: 98.4%
- 10x: 96.5%
- 20x: 93.7%
|
| Validation Efficiency |
|
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene encodes a nuclear protein, which is expressed in heart, aorta, and in smooth muscle cell-containing tissues. It functions as a transcriptional co-activator of serum response factor (SRF) and modulates expression of cardiac and smooth muscle-specific SRF-target genes, and thus may play a crucial role in cardiogenesis and differentiation of the smooth muscle cell lineage. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Sep 2009]
PHENOTYPE: Mice homozygous for a null mutation exhibit embryonic lethality and fail to form vascular smooth muscle. [provided by MGI curators]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 85 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| A2ml1 |
T |
C |
6: 128,535,289 (GRCm39) |
D807G |
possibly damaging |
Het |
| Actl9 |
T |
A |
17: 33,652,323 (GRCm39) |
W128R |
probably damaging |
Het |
| Aggf1 |
T |
C |
13: 95,492,924 (GRCm39) |
I562V |
probably damaging |
Het |
| Ano3 |
T |
A |
2: 110,715,200 (GRCm39) |
E79D |
probably benign |
Het |
| Apobec1 |
T |
A |
6: 122,558,504 (GRCm39) |
I84F |
probably damaging |
Het |
| Atp6v1b2 |
T |
C |
8: 69,562,637 (GRCm39) |
F458L |
possibly damaging |
Het |
| Bco2 |
A |
T |
9: 50,445,926 (GRCm39) |
V490E |
probably damaging |
Het |
| Catsperg1 |
G |
A |
7: 28,884,615 (GRCm39) |
|
probably benign |
Het |
| Cdc37 |
T |
C |
9: 21,054,292 (GRCm39) |
K111R |
probably damaging |
Het |
| Cfap54 |
T |
C |
10: 92,744,745 (GRCm39) |
|
probably benign |
Het |
| Cfap91 |
G |
A |
16: 38,148,736 (GRCm39) |
P231S |
probably damaging |
Het |
| Cplane1 |
T |
A |
15: 8,223,870 (GRCm39) |
Y878N |
probably damaging |
Het |
| Cpox |
T |
A |
16: 58,495,608 (GRCm39) |
C308* |
probably null |
Het |
| Cracdl |
A |
T |
1: 37,683,710 (GRCm39) |
M1K |
probably null |
Het |
| Ctnna3 |
T |
G |
10: 64,511,688 (GRCm39) |
M626R |
probably damaging |
Het |
| Cyp2c68 |
T |
C |
19: 39,727,873 (GRCm39) |
E93G |
probably benign |
Het |
| Cyp2s1 |
G |
A |
7: 25,505,475 (GRCm39) |
R330W |
probably damaging |
Het |
| Diaph1 |
C |
T |
18: 37,989,553 (GRCm39) |
V860I |
possibly damaging |
Het |
| Dicer1 |
A |
G |
12: 104,668,750 (GRCm39) |
S1311P |
probably damaging |
Het |
| Dpyd |
G |
A |
3: 118,692,852 (GRCm39) |
R332K |
probably benign |
Het |
| E130308A19Rik |
G |
A |
4: 59,719,716 (GRCm39) |
R416H |
probably damaging |
Het |
| Eef1d |
T |
C |
15: 75,775,005 (GRCm39) |
D218G |
probably benign |
Het |
| Eif2ak1 |
T |
C |
5: 143,818,984 (GRCm39) |
V215A |
probably damaging |
Het |
| Eif2ak4 |
T |
C |
2: 118,272,577 (GRCm39) |
|
probably null |
Het |
| Fcrl5 |
T |
C |
3: 87,365,099 (GRCm39) |
S583P |
possibly damaging |
Het |
| Garin5b |
A |
G |
7: 4,762,392 (GRCm39) |
S246P |
possibly damaging |
Het |
| Grid2ip |
C |
A |
5: 143,358,798 (GRCm39) |
Q29K |
possibly damaging |
Het |
| Htr1f |
A |
T |
16: 64,746,262 (GRCm39) |
N343K |
probably damaging |
Het |
| Hvcn1 |
T |
C |
5: 122,354,428 (GRCm39) |
|
probably null |
Het |
| Igf2r |
T |
C |
17: 12,910,951 (GRCm39) |
I1956V |
probably benign |
Het |
| Impdh2 |
A |
T |
9: 108,439,018 (GRCm39) |
|
probably null |
Het |
| Impdh2 |
C |
T |
9: 108,439,019 (GRCm39) |
T96I |
possibly damaging |
Het |
| Lactb |
C |
G |
9: 66,877,974 (GRCm39) |
G285A |
probably benign |
Het |
| Lrrc43 |
T |
C |
5: 123,639,305 (GRCm39) |
S445P |
probably damaging |
Het |
| Mapk12 |
T |
G |
15: 89,019,848 (GRCm39) |
M120L |
probably benign |
Het |
| Mroh8 |
C |
G |
2: 157,065,956 (GRCm39) |
A669P |
probably damaging |
Het |
| Mrpl38 |
A |
C |
11: 116,022,844 (GRCm39) |
H373Q |
probably benign |
Het |
| Naprt |
A |
G |
15: 75,764,314 (GRCm39) |
F300S |
probably damaging |
Het |
| Ncam2 |
T |
C |
16: 81,258,531 (GRCm39) |
I271T |
probably damaging |
Het |
| Nek4 |
A |
G |
14: 30,701,995 (GRCm39) |
T582A |
probably benign |
Het |
| Notch2 |
C |
T |
3: 97,978,286 (GRCm39) |
T89I |
probably benign |
Het |
| Notch2 |
G |
A |
3: 98,018,914 (GRCm39) |
R692H |
probably benign |
Het |
| Nt5c3 |
A |
T |
6: 56,860,666 (GRCm39) |
N296K |
probably damaging |
Het |
| Nt5c3b |
T |
A |
11: 100,327,036 (GRCm39) |
I87F |
probably damaging |
Het |
| Oas3 |
T |
C |
5: 120,904,209 (GRCm39) |
Q555R |
unknown |
Het |
| Or2ag17 |
A |
G |
7: 106,389,533 (GRCm39) |
V225A |
probably damaging |
Het |
| Or5p69 |
A |
T |
7: 107,967,438 (GRCm39) |
H247L |
probably damaging |
Het |
| Or9g19 |
T |
A |
2: 85,600,273 (GRCm39) |
S43T |
probably benign |
Het |
| P3h1 |
C |
A |
4: 119,098,727 (GRCm39) |
Q410K |
probably benign |
Het |
| Pax3 |
A |
G |
1: 78,172,078 (GRCm39) |
V44A |
possibly damaging |
Het |
| Pde1c |
T |
A |
6: 56,151,926 (GRCm39) |
L252F |
probably damaging |
Het |
| Pdzd7 |
T |
A |
19: 45,024,529 (GRCm39) |
T497S |
probably benign |
Het |
| Piezo2 |
T |
C |
18: 63,155,552 (GRCm39) |
T253A |
probably damaging |
Het |
| Pipox |
T |
C |
11: 77,782,965 (GRCm39) |
E79G |
probably damaging |
Het |
| Pole |
G |
T |
5: 110,451,459 (GRCm39) |
M829I |
probably damaging |
Het |
| Ppp1r12c |
A |
T |
7: 4,492,771 (GRCm39) |
L156Q |
probably damaging |
Het |
| Psme2b |
T |
G |
11: 48,836,609 (GRCm39) |
T113P |
probably damaging |
Het |
| Ptprq |
A |
G |
10: 107,416,081 (GRCm39) |
I1739T |
possibly damaging |
Het |
| Qser1 |
T |
C |
2: 104,620,021 (GRCm39) |
T174A |
probably damaging |
Het |
| Rcor3 |
T |
G |
1: 191,814,736 (GRCm39) |
D81A |
probably damaging |
Het |
| Rev3l |
T |
C |
10: 39,724,045 (GRCm39) |
V785A |
probably benign |
Het |
| Rnf11 |
T |
C |
4: 109,314,119 (GRCm39) |
D90G |
probably benign |
Het |
| Sh3tc1 |
GCCTCCTCCTCCTCCTCC |
GCCTCCTCCTCCTCC |
5: 35,881,410 (GRCm39) |
|
probably benign |
Het |
| Smad2 |
T |
A |
18: 76,395,623 (GRCm39) |
S21T |
probably benign |
Het |
| Smc4 |
A |
G |
3: 68,933,221 (GRCm39) |
D639G |
probably damaging |
Het |
| Smtn |
A |
T |
11: 3,474,664 (GRCm39) |
S716T |
possibly damaging |
Het |
| Smug1 |
G |
T |
15: 103,064,136 (GRCm39) |
Q262K |
probably benign |
Het |
| Sspo |
G |
T |
6: 48,428,794 (GRCm39) |
G403V |
probably benign |
Het |
| Tas2r131 |
A |
G |
6: 132,934,414 (GRCm39) |
F132L |
possibly damaging |
Het |
| Tgm3 |
T |
C |
2: 129,886,582 (GRCm39) |
|
probably null |
Het |
| Tigd2 |
C |
T |
6: 59,187,358 (GRCm39) |
T75M |
probably benign |
Het |
| Tnfrsf13b |
T |
C |
11: 61,038,413 (GRCm39) |
V232A |
probably benign |
Het |
| Tnfrsf21 |
C |
T |
17: 43,349,104 (GRCm39) |
H239Y |
probably benign |
Het |
| Trim47 |
A |
G |
11: 115,998,716 (GRCm39) |
L301S |
probably damaging |
Het |
| Trim75 |
G |
A |
8: 65,436,442 (GRCm39) |
H3Y |
probably benign |
Het |
| Trp53bp1 |
C |
A |
2: 121,082,349 (GRCm39) |
A317S |
probably null |
Het |
| Tsbp1 |
G |
T |
17: 34,664,473 (GRCm39) |
|
probably null |
Het |
| Ttc29 |
G |
C |
8: 79,003,466 (GRCm39) |
L227F |
probably benign |
Het |
| Ttc39d |
G |
A |
17: 80,523,886 (GRCm39) |
D182N |
possibly damaging |
Het |
| Ttll10 |
T |
A |
4: 156,129,818 (GRCm39) |
R164* |
probably null |
Het |
| Ufsp2 |
T |
A |
8: 46,449,780 (GRCm39) |
D447E |
probably benign |
Het |
| Ugt2b37 |
T |
A |
5: 87,399,691 (GRCm39) |
L272F |
possibly damaging |
Het |
| Vps13b |
T |
C |
15: 35,472,196 (GRCm39) |
V833A |
probably benign |
Het |
| Zbbx |
T |
C |
3: 74,989,165 (GRCm39) |
T308A |
probably benign |
Het |
| Zfp933 |
G |
A |
4: 147,910,919 (GRCm39) |
Q226* |
probably null |
Het |
|
| Other mutations in Myocd |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00092:Myocd
|
APN |
11 |
65,071,770 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
IGL00481:Myocd
|
APN |
11 |
65,077,980 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL00857:Myocd
|
APN |
11 |
65,069,662 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
IGL01012:Myocd
|
APN |
11 |
65,075,451 (GRCm39) |
missense |
possibly damaging |
0.51 |
|
IGL01570:Myocd
|
APN |
11 |
65,091,633 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL01865:Myocd
|
APN |
11 |
65,091,723 (GRCm39) |
missense |
probably benign |
0.30 |
|
IGL01938:Myocd
|
APN |
11 |
65,077,914 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02324:Myocd
|
APN |
11 |
65,069,484 (GRCm39) |
missense |
probably benign |
0.01 |
|
IGL02598:Myocd
|
APN |
11 |
65,074,296 (GRCm39) |
missense |
probably benign |
0.31 |
|
IGL02886:Myocd
|
APN |
11 |
65,069,569 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL03008:Myocd
|
APN |
11 |
65,078,392 (GRCm39) |
missense |
probably damaging |
0.98 |
|
IGL03034:Myocd
|
APN |
11 |
65,109,511 (GRCm39) |
missense |
probably benign |
0.00 |
|
harvey
|
UTSW |
11 |
65,069,856 (GRCm39) |
splice site |
probably null |
|
|
irma
|
UTSW |
11 |
65,087,220 (GRCm39) |
missense |
probably benign |
0.02 |
|
myra
|
UTSW |
11 |
65,069,685 (GRCm39) |
missense |
probably benign |
0.10 |
|
Nate
|
UTSW |
11 |
65,123,914 (GRCm39) |
splice site |
probably null |
|
|
R0838_Myocd_053
|
UTSW |
11 |
65,069,758 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0078:Myocd
|
UTSW |
11 |
65,078,290 (GRCm39) |
missense |
possibly damaging |
0.96 |
|
R0097:Myocd
|
UTSW |
11 |
65,069,840 (GRCm39) |
missense |
possibly damaging |
0.67 |
|
R0097:Myocd
|
UTSW |
11 |
65,069,840 (GRCm39) |
missense |
possibly damaging |
0.67 |
|
R0234:Myocd
|
UTSW |
11 |
65,078,066 (GRCm39) |
missense |
probably benign |
0.01 |
|
R0234:Myocd
|
UTSW |
11 |
65,078,066 (GRCm39) |
missense |
probably benign |
0.01 |
|
R0453:Myocd
|
UTSW |
11 |
65,087,051 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0838:Myocd
|
UTSW |
11 |
65,069,758 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0899:Myocd
|
UTSW |
11 |
65,086,018 (GRCm39) |
missense |
possibly damaging |
0.50 |
|
R1167:Myocd
|
UTSW |
11 |
65,087,203 (GRCm39) |
missense |
possibly damaging |
0.77 |
|
R1472:Myocd
|
UTSW |
11 |
65,078,330 (GRCm39) |
missense |
probably benign |
0.01 |
|
R1508:Myocd
|
UTSW |
11 |
65,075,342 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R1620:Myocd
|
UTSW |
11 |
65,087,220 (GRCm39) |
missense |
probably benign |
0.02 |
|
R1630:Myocd
|
UTSW |
11 |
65,087,220 (GRCm39) |
missense |
probably benign |
0.02 |
|
R1731:Myocd
|
UTSW |
11 |
65,091,714 (GRCm39) |
missense |
probably benign |
0.30 |
|
R1740:Myocd
|
UTSW |
11 |
65,109,347 (GRCm39) |
splice site |
probably benign |
|
|
R1769:Myocd
|
UTSW |
11 |
65,069,527 (GRCm39) |
missense |
probably benign |
0.01 |
|
R1823:Myocd
|
UTSW |
11 |
65,069,496 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1968:Myocd
|
UTSW |
11 |
65,091,733 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1997:Myocd
|
UTSW |
11 |
65,095,147 (GRCm39) |
nonsense |
probably null |
|
|
R2018:Myocd
|
UTSW |
11 |
65,077,854 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2105:Myocd
|
UTSW |
11 |
65,109,484 (GRCm39) |
nonsense |
probably null |
|
|
R2314:Myocd
|
UTSW |
11 |
65,091,633 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4330:Myocd
|
UTSW |
11 |
65,114,590 (GRCm39) |
missense |
probably benign |
0.12 |
|
R4331:Myocd
|
UTSW |
11 |
65,114,590 (GRCm39) |
missense |
probably benign |
0.12 |
|
R4603:Myocd
|
UTSW |
11 |
65,078,571 (GRCm39) |
missense |
possibly damaging |
0.82 |
|
R4619:Myocd
|
UTSW |
11 |
65,069,254 (GRCm39) |
utr 3 prime |
probably benign |
|
|
R4631:Myocd
|
UTSW |
11 |
65,069,685 (GRCm39) |
missense |
probably benign |
0.10 |
|
R4865:Myocd
|
UTSW |
11 |
65,069,856 (GRCm39) |
splice site |
probably null |
|
|
R4974:Myocd
|
UTSW |
11 |
65,074,299 (GRCm39) |
missense |
possibly damaging |
0.78 |
|
R4976:Myocd
|
UTSW |
11 |
65,112,876 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5478:Myocd
|
UTSW |
11 |
65,123,914 (GRCm39) |
splice site |
probably null |
|
|
R5499:Myocd
|
UTSW |
11 |
65,069,575 (GRCm39) |
missense |
possibly damaging |
0.62 |
|
R6052:Myocd
|
UTSW |
11 |
65,087,082 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6356:Myocd
|
UTSW |
11 |
65,109,396 (GRCm39) |
splice site |
probably null |
|
|
R7144:Myocd
|
UTSW |
11 |
65,109,474 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7261:Myocd
|
UTSW |
11 |
65,078,422 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R7354:Myocd
|
UTSW |
11 |
65,078,319 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7461:Myocd
|
UTSW |
11 |
65,109,429 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7613:Myocd
|
UTSW |
11 |
65,109,429 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7718:Myocd
|
UTSW |
11 |
65,109,452 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7956:Myocd
|
UTSW |
11 |
65,160,494 (GRCm39) |
missense |
possibly damaging |
0.50 |
|
R8345:Myocd
|
UTSW |
11 |
65,077,958 (GRCm39) |
nonsense |
probably null |
|
|
R8975:Myocd
|
UTSW |
11 |
65,069,287 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9051:Myocd
|
UTSW |
11 |
65,077,795 (GRCm39) |
missense |
probably benign |
|
|
R9400:Myocd
|
UTSW |
11 |
65,086,934 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9469:Myocd
|
UTSW |
11 |
65,087,220 (GRCm39) |
missense |
probably benign |
0.02 |
|
R9565:Myocd
|
UTSW |
11 |
65,078,209 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9567:Myocd
|
UTSW |
11 |
65,078,410 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9585:Myocd
|
UTSW |
11 |
65,095,192 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9710:Myocd
|
UTSW |
11 |
65,087,167 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9768:Myocd
|
UTSW |
11 |
65,078,217 (GRCm39) |
missense |
probably damaging |
1.00 |
|
X0057:Myocd
|
UTSW |
11 |
65,074,271 (GRCm39) |
missense |
possibly damaging |
0.87 |
|
Z1186:Myocd
|
UTSW |
11 |
65,075,418 (GRCm39) |
missense |
probably benign |
|
|
Z1187:Myocd
|
UTSW |
11 |
65,075,418 (GRCm39) |
missense |
probably benign |
|
|
Z1188:Myocd
|
UTSW |
11 |
65,075,418 (GRCm39) |
missense |
probably benign |
|
|
Z1189:Myocd
|
UTSW |
11 |
65,075,418 (GRCm39) |
missense |
probably benign |
|
|
Z1190:Myocd
|
UTSW |
11 |
65,075,418 (GRCm39) |
missense |
probably benign |
|
|
Z1191:Myocd
|
UTSW |
11 |
65,075,418 (GRCm39) |
missense |
probably benign |
|
|
Z1192:Myocd
|
UTSW |
11 |
65,075,418 (GRCm39) |
missense |
probably benign |
|
|
| Predicted Primers |
PCR Primer
(F):5'- TGGCAAGGAAGCATCCACTGTG -3'
(R):5'- ACTCTGCTGTGTTGAATCCTTAGGC -3'
Sequencing Primer
(F):5'- GAAGCATCCACTGTGTTTCTC -3'
(R):5'- GCAAGCATAATTCTGTTTCTAGGGC -3'
|
| Posted On |
2013-06-12 |
Incidental Mutation