Incidental Mutation 'R6128:Robo1'
| ID |
487543 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Robo1
|
| Ensembl Gene |
ENSMUSG00000022883 |
| Gene Name |
roundabout guidance receptor 1 |
| Synonyms |
DUTT1 |
| MMRRC Submission |
044275-MU
|
| Accession Numbers |
|
| Essential gene? |
Essential
(E-score: 1.000)
|
| Stock # |
R6128 (G1)
|
| Quality Score |
191.009 |
|
Status
|
Not validated
|
| Chromosome |
16 |
| Chromosomal Location |
72105194-72842983 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
A to T
at 72809956 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Methionine to Leucine
at position 1235
(M1235L)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000023600
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000023600]
|
| AlphaFold |
no structure available at present |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000023600
AA Change: M1235L
PolyPhen 2
Score 0.000 (Sensitivity: 1.00; Specificity: 0.00)
|
| SMART Domains |
Protein: ENSMUSP00000023600
Gene: ENSMUSG00000022883
AA Change: M1235L
| Domain | Start | End | E-Value | Type |
|---|
|
IGc2
|
41 |
115 |
3.15e-10 |
SMART |
|
IGc2
|
143 |
208 |
2.52e-9 |
SMART |
|
IGc2
|
235 |
298 |
3.85e-14 |
SMART |
|
IGv
|
328 |
391 |
3.71e-7 |
SMART |
|
IGc2
|
428 |
493 |
2.46e-12 |
SMART |
|
FN3
|
522 |
604 |
3.17e-13 |
SMART |
|
FN3
|
634 |
721 |
1.66e0 |
SMART |
|
FN3
|
736 |
822 |
4.28e-10 |
SMART |
|
low complexity region
|
1108 |
1125 |
N/A |
INTRINSIC |
|
low complexity region
|
1148 |
1157 |
N/A |
INTRINSIC |
|
low complexity region
|
1186 |
1197 |
N/A |
INTRINSIC |
|
low complexity region
|
1249 |
1269 |
N/A |
INTRINSIC |
|
low complexity region
|
1282 |
1298 |
N/A |
INTRINSIC |
|
low complexity region
|
1345 |
1357 |
N/A |
INTRINSIC |
|
low complexity region
|
1362 |
1380 |
N/A |
INTRINSIC |
|
low complexity region
|
1442 |
1449 |
N/A |
INTRINSIC |
|
low complexity region
|
1563 |
1576 |
N/A |
INTRINSIC |
|
low complexity region
|
1602 |
1611 |
N/A |
INTRINSIC |
|
| Predicted Effect |
unknown
Transcript: ENSMUST00000232205
AA Change: M1244L
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000232432
|
| Meta Mutation Damage Score |
0.0864 |
| Coding Region Coverage |
- 1x: 99.9%
- 3x: 99.7%
- 10x: 98.5%
- 20x: 95.9%
|
| Validation Efficiency |
|
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] Bilateral symmetric nervous systems have special midline structures that establish a partition between the two mirror image halves. Some axons project toward and across the midline in response to long-range chemoattractants emanating from the midline. The product of this gene is a member of the immunoglobulin gene superfamily and encodes an integral membrane protein that functions in axon guidance and neuronal precursor cell migration. This receptor is activated by SLIT-family proteins, resulting in a repulsive effect on glioma cell guidance in the developing brain. A related gene is located at an adjacent region on chromosome 3. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2009]
PHENOTYPE: Mice homozygous for a reporter allele show altered axon guidance. Mice homozygous for a null allele die at birth showing aberrant axon pathfinding and cortical interneuron migration. Homozygotes for another null allele show neonatal death, aphagia, delayed lung maturation and bronchial hyperplasia. [provided by MGI curators]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 78 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 4930553M12Rik |
T |
C |
4: 88,786,596 (GRCm39) |
I7M |
unknown |
Het |
| A430033K04Rik |
A |
G |
5: 138,646,038 (GRCm39) |
H641R |
probably damaging |
Het |
| Acyp2 |
C |
T |
11: 30,456,354 (GRCm39) |
E98K |
possibly damaging |
Het |
| Asah1 |
C |
T |
8: 41,807,092 (GRCm39) |
V111M |
probably damaging |
Het |
| Ascc3 |
T |
C |
10: 50,526,734 (GRCm39) |
L611P |
probably damaging |
Het |
| Atl2 |
C |
A |
17: 80,172,470 (GRCm39) |
|
probably null |
Het |
| Bhlhe22 |
A |
T |
3: 18,109,987 (GRCm39) |
S346C |
probably damaging |
Het |
| Bicc1 |
T |
C |
10: 70,776,313 (GRCm39) |
|
probably null |
Het |
| Bptf |
G |
T |
11: 106,965,516 (GRCm39) |
A1163D |
possibly damaging |
Het |
| Bub1b |
T |
A |
2: 118,448,293 (GRCm39) |
C382S |
probably benign |
Het |
| Carmil1 |
A |
T |
13: 24,197,177 (GRCm39) |
Y158* |
probably null |
Het |
| Ccdc175 |
A |
T |
12: 72,175,933 (GRCm39) |
I473K |
probably benign |
Het |
| Ccdc18 |
A |
G |
5: 108,311,625 (GRCm39) |
I444V |
possibly damaging |
Het |
| Cep131 |
T |
A |
11: 119,956,801 (GRCm39) |
I880F |
probably damaging |
Het |
| Ces2e |
T |
A |
8: 105,655,428 (GRCm39) |
I117N |
probably benign |
Het |
| Clk2 |
C |
T |
3: 89,081,531 (GRCm39) |
T289M |
probably damaging |
Het |
| Crocc2 |
A |
T |
1: 93,122,123 (GRCm39) |
D672V |
probably benign |
Het |
| Cul7 |
T |
A |
17: 46,962,588 (GRCm39) |
I73N |
probably damaging |
Het |
| Cyp2d12 |
C |
A |
15: 82,443,166 (GRCm39) |
D358E |
probably benign |
Het |
| Cyp7a1 |
A |
G |
4: 6,272,788 (GRCm39) |
S142P |
possibly damaging |
Het |
| Daw1 |
T |
A |
1: 83,183,647 (GRCm39) |
C232* |
probably null |
Het |
| Dhx9 |
T |
C |
1: 153,353,835 (GRCm39) |
K195R |
probably damaging |
Het |
| Dnase1l1 |
C |
T |
X: 73,320,644 (GRCm39) |
|
probably null |
Het |
| Dpp3 |
A |
G |
19: 4,972,420 (GRCm39) |
V168A |
probably benign |
Het |
| Eml2 |
G |
A |
7: 18,935,088 (GRCm39) |
V432I |
probably damaging |
Het |
| Ercc6l2 |
T |
C |
13: 64,001,563 (GRCm39) |
V459A |
probably damaging |
Het |
| Erp44 |
A |
T |
4: 48,243,493 (GRCm39) |
N38K |
probably damaging |
Het |
| Fam135a |
A |
G |
1: 24,069,821 (GRCm39) |
|
probably null |
Het |
| Fblim1 |
G |
A |
4: 141,312,033 (GRCm39) |
R231C |
probably damaging |
Het |
| Fdps |
T |
C |
3: 89,006,740 (GRCm39) |
E117G |
possibly damaging |
Het |
| Gbp4 |
A |
C |
5: 105,283,030 (GRCm39) |
V80G |
possibly damaging |
Het |
| Glt1d1 |
A |
T |
5: 127,754,335 (GRCm39) |
D179V |
probably damaging |
Het |
| Gtf2a1l |
T |
A |
17: 89,002,086 (GRCm39) |
V314E |
probably null |
Het |
| Gzmf |
G |
T |
14: 56,443,443 (GRCm39) |
Y178* |
probably null |
Het |
| Hira |
C |
T |
16: 18,751,727 (GRCm39) |
P509S |
probably benign |
Het |
| Ifi44 |
T |
C |
3: 151,454,823 (GRCm39) |
N134S |
probably benign |
Het |
| Igfbp2 |
T |
A |
1: 72,863,958 (GRCm39) |
C74S |
probably damaging |
Het |
| Il24 |
A |
G |
1: 130,813,435 (GRCm39) |
L54P |
probably damaging |
Het |
| Ints10 |
T |
C |
8: 69,274,904 (GRCm39) |
|
probably null |
Het |
| Ipo9 |
A |
G |
1: 135,318,311 (GRCm39) |
C700R |
possibly damaging |
Het |
| Kalrn |
T |
A |
16: 34,033,255 (GRCm39) |
Q469L |
probably damaging |
Het |
| Lrp1b |
T |
G |
2: 40,750,667 (GRCm39) |
I2966L |
probably benign |
Het |
| Lta |
C |
A |
17: 35,422,817 (GRCm39) |
V169L |
possibly damaging |
Het |
| Lyst |
T |
C |
13: 13,933,964 (GRCm39) |
V3554A |
possibly damaging |
Het |
| Mobp |
A |
G |
9: 119,997,392 (GRCm39) |
|
probably benign |
Het |
| Myorg |
T |
A |
4: 41,498,445 (GRCm39) |
N395I |
probably damaging |
Het |
| Or10d1 |
C |
G |
9: 39,484,549 (GRCm39) |
R2T |
probably benign |
Het |
| Or4b1d |
A |
T |
2: 89,968,954 (GRCm39) |
C176* |
probably null |
Het |
| Or8c14-ps1 |
T |
C |
9: 38,101,299 (GRCm39) |
S93P |
probably benign |
Het |
| Pacs1 |
A |
T |
19: 5,202,400 (GRCm39) |
|
probably null |
Het |
| Phf21a |
G |
T |
2: 92,181,953 (GRCm39) |
|
probably null |
Het |
| Pick1 |
T |
A |
15: 79,123,896 (GRCm39) |
M89K |
probably damaging |
Het |
| Pik3cb |
T |
C |
9: 98,946,152 (GRCm39) |
D558G |
possibly damaging |
Het |
| Pnma8a |
A |
G |
7: 16,694,661 (GRCm39) |
D172G |
probably benign |
Het |
| Polr2a |
A |
C |
11: 69,627,803 (GRCm39) |
V1368G |
probably damaging |
Het |
| Pomt2 |
A |
G |
12: 87,158,109 (GRCm39) |
|
probably null |
Het |
| Pou2f1 |
T |
C |
1: 165,703,056 (GRCm39) |
|
probably benign |
Het |
| Rnf145 |
T |
C |
11: 44,446,018 (GRCm39) |
V284A |
probably damaging |
Het |
| Rsf1 |
ATGGCG |
ATGGCGACGGTGGCG |
7: 97,229,111 (GRCm39) |
|
probably benign |
Het |
| Ryr3 |
C |
T |
2: 112,784,639 (GRCm39) |
|
probably null |
Het |
| Scamp1 |
A |
C |
13: 94,344,735 (GRCm39) |
L202R |
possibly damaging |
Het |
| Snx25 |
C |
T |
8: 46,558,240 (GRCm39) |
V110I |
probably benign |
Het |
| Spata31e2 |
G |
A |
1: 26,724,506 (GRCm39) |
P225S |
probably benign |
Het |
| Susd6 |
T |
A |
12: 80,915,388 (GRCm39) |
H124Q |
possibly damaging |
Het |
| Tarm1 |
T |
C |
7: 3,537,720 (GRCm39) |
T248A |
probably benign |
Het |
| Tc2n |
A |
G |
12: 101,675,748 (GRCm39) |
M1T |
probably null |
Het |
| Tcerg1 |
C |
A |
18: 42,644,563 (GRCm39) |
|
probably null |
Het |
| Ticrr |
C |
A |
7: 79,343,716 (GRCm39) |
P1194T |
probably damaging |
Het |
| Trim31 |
T |
G |
17: 37,220,491 (GRCm39) |
V469G |
probably benign |
Het |
| Vcp |
T |
C |
4: 42,980,941 (GRCm39) |
E723G |
probably benign |
Het |
| Vmn1r177 |
C |
A |
7: 23,565,267 (GRCm39) |
S203I |
probably damaging |
Het |
| Vmn1r177 |
T |
A |
7: 23,565,268 (GRCm39) |
S203C |
probably damaging |
Het |
| Vmn1r210 |
A |
T |
13: 23,012,277 (GRCm39) |
L3* |
probably null |
Het |
| Wdr27 |
T |
A |
17: 15,152,796 (GRCm39) |
R104* |
probably null |
Het |
| Wnk1 |
A |
C |
6: 119,940,747 (GRCm39) |
|
probably null |
Het |
| Zfp157 |
A |
G |
5: 138,453,281 (GRCm39) |
E88G |
possibly damaging |
Het |
| Zfp708 |
A |
T |
13: 67,222,965 (GRCm39) |
L22Q |
probably damaging |
Het |
| Zfp788 |
T |
C |
7: 41,299,785 (GRCm39) |
F787S |
probably damaging |
Het |
|
| Other mutations in Robo1 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL01766:Robo1
|
APN |
16 |
72,801,553 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL01937:Robo1
|
APN |
16 |
72,759,114 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01945:Robo1
|
APN |
16 |
72,759,114 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02151:Robo1
|
APN |
16 |
72,786,504 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL02232:Robo1
|
APN |
16 |
72,768,872 (GRCm39) |
missense |
possibly damaging |
0.59 |
|
IGL02282:Robo1
|
APN |
16 |
72,539,026 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02590:Robo1
|
APN |
16 |
72,840,020 (GRCm39) |
missense |
probably benign |
0.06 |
|
IGL02874:Robo1
|
APN |
16 |
72,809,806 (GRCm39) |
missense |
probably damaging |
0.96 |
|
IGL02974:Robo1
|
APN |
16 |
72,803,750 (GRCm39) |
missense |
probably benign |
0.09 |
|
IGL03233:Robo1
|
APN |
16 |
72,767,081 (GRCm39) |
missense |
probably damaging |
0.99 |
|
PIT4378001:Robo1
|
UTSW |
16 |
72,801,423 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0079:Robo1
|
UTSW |
16 |
72,730,230 (GRCm39) |
splice site |
probably benign |
|
|
R0254:Robo1
|
UTSW |
16 |
72,461,058 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0366:Robo1
|
UTSW |
16 |
72,539,133 (GRCm39) |
missense |
possibly damaging |
0.52 |
|
R0410:Robo1
|
UTSW |
16 |
72,768,872 (GRCm39) |
missense |
possibly damaging |
0.59 |
|
R0511:Robo1
|
UTSW |
16 |
72,810,013 (GRCm39) |
critical splice donor site |
probably null |
|
|
R0563:Robo1
|
UTSW |
16 |
72,769,174 (GRCm39) |
missense |
probably benign |
0.01 |
|
R0637:Robo1
|
UTSW |
16 |
72,798,839 (GRCm39) |
missense |
probably benign |
0.29 |
|
R1239:Robo1
|
UTSW |
16 |
72,821,430 (GRCm39) |
splice site |
probably null |
|
|
R1773:Robo1
|
UTSW |
16 |
72,801,399 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1777:Robo1
|
UTSW |
16 |
72,801,555 (GRCm39) |
missense |
probably benign |
|
|
R1901:Robo1
|
UTSW |
16 |
72,757,092 (GRCm39) |
missense |
probably null |
1.00 |
|
R1902:Robo1
|
UTSW |
16 |
72,757,092 (GRCm39) |
missense |
probably null |
1.00 |
|
R1903:Robo1
|
UTSW |
16 |
72,757,092 (GRCm39) |
missense |
probably null |
1.00 |
|
R1996:Robo1
|
UTSW |
16 |
72,767,067 (GRCm39) |
missense |
probably benign |
0.40 |
|
R2040:Robo1
|
UTSW |
16 |
72,730,630 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2266:Robo1
|
UTSW |
16 |
72,775,660 (GRCm39) |
missense |
probably benign |
|
|
R2269:Robo1
|
UTSW |
16 |
72,775,660 (GRCm39) |
missense |
probably benign |
|
|
R2433:Robo1
|
UTSW |
16 |
72,767,127 (GRCm39) |
missense |
probably benign |
0.01 |
|
R3084:Robo1
|
UTSW |
16 |
72,801,625 (GRCm39) |
missense |
probably benign |
0.02 |
|
R3085:Robo1
|
UTSW |
16 |
72,798,898 (GRCm39) |
missense |
possibly damaging |
0.81 |
|
R3150:Robo1
|
UTSW |
16 |
72,767,157 (GRCm39) |
missense |
possibly damaging |
0.57 |
|
R3418:Robo1
|
UTSW |
16 |
72,832,805 (GRCm39) |
missense |
probably benign |
0.00 |
|
R3610:Robo1
|
UTSW |
16 |
72,780,658 (GRCm39) |
missense |
probably benign |
0.00 |
|
R3940:Robo1
|
UTSW |
16 |
72,806,631 (GRCm39) |
missense |
probably benign |
|
|
R3953:Robo1
|
UTSW |
16 |
72,821,226 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4692:Robo1
|
UTSW |
16 |
72,757,090 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4726:Robo1
|
UTSW |
16 |
72,768,931 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4814:Robo1
|
UTSW |
16 |
72,768,923 (GRCm39) |
missense |
probably benign |
0.11 |
|
R4884:Robo1
|
UTSW |
16 |
72,701,639 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4992:Robo1
|
UTSW |
16 |
72,776,756 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R5150:Robo1
|
UTSW |
16 |
72,769,192 (GRCm39) |
missense |
possibly damaging |
0.79 |
|
R5183:Robo1
|
UTSW |
16 |
72,539,038 (GRCm39) |
missense |
probably benign |
0.03 |
|
R5360:Robo1
|
UTSW |
16 |
72,732,665 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R5629:Robo1
|
UTSW |
16 |
72,780,598 (GRCm39) |
missense |
probably benign |
0.33 |
|
R5804:Robo1
|
UTSW |
16 |
72,840,077 (GRCm39) |
critical splice donor site |
probably null |
|
|
R6107:Robo1
|
UTSW |
16 |
72,780,717 (GRCm39) |
missense |
probably benign |
0.00 |
|
R6127:Robo1
|
UTSW |
16 |
72,809,956 (GRCm39) |
missense |
probably benign |
|
|
R6129:Robo1
|
UTSW |
16 |
72,809,956 (GRCm39) |
missense |
probably benign |
|
|
R6191:Robo1
|
UTSW |
16 |
72,730,696 (GRCm39) |
missense |
probably benign |
0.00 |
|
R6357:Robo1
|
UTSW |
16 |
72,767,190 (GRCm39) |
missense |
probably benign |
0.00 |
|
R6408:Robo1
|
UTSW |
16 |
72,768,934 (GRCm39) |
missense |
probably benign |
0.00 |
|
R6516:Robo1
|
UTSW |
16 |
72,821,241 (GRCm39) |
missense |
probably benign |
0.14 |
|
R6600:Robo1
|
UTSW |
16 |
72,786,543 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6802:Robo1
|
UTSW |
16 |
72,730,201 (GRCm39) |
missense |
probably benign |
0.17 |
|
R7105:Robo1
|
UTSW |
16 |
72,539,049 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7189:Robo1
|
UTSW |
16 |
72,757,039 (GRCm39) |
nonsense |
probably null |
|
|
R7290:Robo1
|
UTSW |
16 |
72,801,408 (GRCm39) |
missense |
probably benign |
0.03 |
|
R7296:Robo1
|
UTSW |
16 |
72,786,519 (GRCm39) |
nonsense |
probably null |
|
|
R7576:Robo1
|
UTSW |
16 |
72,767,069 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7605:Robo1
|
UTSW |
16 |
72,821,189 (GRCm39) |
missense |
probably benign |
0.14 |
|
R7607:Robo1
|
UTSW |
16 |
72,360,626 (GRCm39) |
missense |
|
|
|
R7634:Robo1
|
UTSW |
16 |
72,839,866 (GRCm39) |
splice site |
probably null |
|
|
R7636:Robo1
|
UTSW |
16 |
72,360,615 (GRCm39) |
missense |
|
|
|
R7857:Robo1
|
UTSW |
16 |
72,767,099 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7966:Robo1
|
UTSW |
16 |
72,780,760 (GRCm39) |
missense |
possibly damaging |
0.62 |
|
R7997:Robo1
|
UTSW |
16 |
72,701,581 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8101:Robo1
|
UTSW |
16 |
72,775,469 (GRCm39) |
missense |
probably benign |
0.03 |
|
R8191:Robo1
|
UTSW |
16 |
72,730,142 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8218:Robo1
|
UTSW |
16 |
72,786,678 (GRCm39) |
missense |
possibly damaging |
0.91 |
|
R8228:Robo1
|
UTSW |
16 |
72,809,768 (GRCm39) |
missense |
probably benign |
0.30 |
|
R8292:Robo1
|
UTSW |
16 |
72,769,420 (GRCm39) |
missense |
possibly damaging |
0.61 |
|
R8298:Robo1
|
UTSW |
16 |
72,769,020 (GRCm39) |
intron |
probably benign |
|
|
R8332:Robo1
|
UTSW |
16 |
72,775,466 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8402:Robo1
|
UTSW |
16 |
72,821,385 (GRCm39) |
missense |
probably benign |
0.16 |
|
R8492:Robo1
|
UTSW |
16 |
72,809,911 (GRCm39) |
missense |
probably benign |
0.06 |
|
R8730:Robo1
|
UTSW |
16 |
72,786,495 (GRCm39) |
missense |
probably benign |
0.08 |
|
R8774:Robo1
|
UTSW |
16 |
72,832,719 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8774-TAIL:Robo1
|
UTSW |
16 |
72,832,719 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8776:Robo1
|
UTSW |
16 |
72,821,141 (GRCm39) |
nonsense |
probably null |
|
|
R8776-TAIL:Robo1
|
UTSW |
16 |
72,821,141 (GRCm39) |
nonsense |
probably null |
|
|
R8905:Robo1
|
UTSW |
16 |
72,539,173 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8913:Robo1
|
UTSW |
16 |
72,701,622 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9003:Robo1
|
UTSW |
16 |
72,539,002 (GRCm39) |
splice site |
probably benign |
|
|
R9246:Robo1
|
UTSW |
16 |
72,769,178 (GRCm39) |
missense |
probably benign |
|
|
R9451:Robo1
|
UTSW |
16 |
72,803,718 (GRCm39) |
missense |
probably benign |
0.10 |
|
R9509:Robo1
|
UTSW |
16 |
72,759,167 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R9652:Robo1
|
UTSW |
16 |
72,821,330 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R9653:Robo1
|
UTSW |
16 |
72,821,330 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R9749:Robo1
|
UTSW |
16 |
72,105,257 (GRCm39) |
start gained |
probably benign |
|
|
Z1176:Robo1
|
UTSW |
16 |
72,774,688 (GRCm39) |
missense |
probably benign |
0.16 |
|
| Predicted Primers |
PCR Primer
(F):5'- AGAAATGCCCTGTCCAGTGC -3'
(R):5'- TTCGAGAGTCAACAGTATTAGTTGG -3'
Sequencing Primer
(F):5'- CCACCTGCGCGGATGTATTTG -3'
(R):5'- CCACTATCTGTATGGGCTAGTAGC -3'
|
| Posted On |
2017-10-10 |
Incidental Mutation