Incidental Mutation 'R6175:Myh13'
| ID |
487709 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Myh13
|
| Ensembl Gene |
ENSMUSG00000060180 |
| Gene Name |
myosin, heavy polypeptide 13, skeletal muscle |
| Synonyms |
EO Myosin, MyHC-eo, extraocular myosin |
| MMRRC Submission |
044317-MU
|
| Accession Numbers |
|
| Essential gene? |
Probably non essential
(E-score: 0.157)
|
| Stock # |
R6175 (G1)
|
| Quality Score |
225.009 |
|
Status
|
Validated
|
| Chromosome |
11 |
| Chromosomal Location |
67217929-67262413 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
A to G
at 67245588 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Aspartic acid to Glycine
at position 1076
(D1076G)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000137731
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000081911]
[ENSMUST00000108684]
[ENSMUST00000180845]
|
| AlphaFold |
B1AR69 |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000081911
AA Change: D1076G
PolyPhen 2
Score 0.005 (Sensitivity: 0.97; Specificity: 0.74)
|
| SMART Domains |
Protein: ENSMUSP00000080584
Gene: ENSMUSG00000060180
AA Change: D1076G
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:Myosin_N
|
35 |
74 |
8e-13 |
PFAM |
|
MYSc
|
80 |
783 |
N/A |
SMART |
|
IQ
|
784 |
806 |
4.6e-1 |
SMART |
|
Pfam:Myosin_tail_1
|
847 |
1928 |
4.6e-159 |
PFAM |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000108684
AA Change: D1076G
PolyPhen 2
Score 0.005 (Sensitivity: 0.97; Specificity: 0.74)
|
| SMART Domains |
Protein: ENSMUSP00000104324
Gene: ENSMUSG00000060180
AA Change: D1076G
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:Myosin_N
|
35 |
76 |
2.8e-14 |
PFAM |
|
MYSc
|
80 |
783 |
N/A |
SMART |
|
IQ
|
784 |
806 |
4.6e-1 |
SMART |
|
low complexity region
|
847 |
858 |
N/A |
INTRINSIC |
|
low complexity region
|
925 |
940 |
N/A |
INTRINSIC |
|
Pfam:Myosin_tail_1
|
1072 |
1930 |
N/A |
PFAM |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000180845
AA Change: D1076G
PolyPhen 2
Score 0.005 (Sensitivity: 0.97; Specificity: 0.74)
|
| SMART Domains |
Protein: ENSMUSP00000137731
Gene: ENSMUSG00000060180
AA Change: D1076G
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:Myosin_N
|
35 |
76 |
2.8e-14 |
PFAM |
|
MYSc
|
80 |
783 |
N/A |
SMART |
|
IQ
|
784 |
806 |
4.6e-1 |
SMART |
|
low complexity region
|
847 |
858 |
N/A |
INTRINSIC |
|
low complexity region
|
925 |
940 |
N/A |
INTRINSIC |
|
Pfam:Myosin_tail_1
|
1072 |
1930 |
N/A |
PFAM |
|
| Meta Mutation Damage Score |
0.1251 |
| Coding Region Coverage |
- 1x: 99.9%
- 3x: 99.5%
- 10x: 97.7%
- 20x: 93.2%
|
| Validation Efficiency |
97% (85/88) |
| Allele List at MGI |
All alleles(4) : Gene trapped(4) |
| Other mutations in this stock |
Total: 88 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 2610008E11Rik |
T |
C |
10: 78,902,448 (GRCm39) |
K623E |
probably damaging |
Het |
| A530064D06Rik |
T |
A |
17: 48,460,016 (GRCm39) |
S227C |
possibly damaging |
Het |
| Adam30 |
A |
T |
3: 98,070,266 (GRCm39) |
I700F |
probably damaging |
Het |
| Adam5 |
A |
T |
8: 25,276,167 (GRCm39) |
M500K |
probably benign |
Het |
| Adgb |
A |
T |
10: 10,274,687 (GRCm39) |
S755T |
possibly damaging |
Het |
| Adgrv1 |
C |
T |
13: 81,534,124 (GRCm39) |
G5819D |
probably damaging |
Het |
| Ank3 |
T |
A |
10: 69,763,557 (GRCm39) |
Y17N |
probably damaging |
Het |
| Ano2 |
A |
T |
6: 125,969,918 (GRCm39) |
M745L |
probably benign |
Het |
| Arap2 |
A |
G |
5: 62,872,074 (GRCm39) |
|
probably null |
Het |
| Atg2a |
A |
T |
19: 6,291,759 (GRCm39) |
|
probably benign |
Het |
| AU021092 |
G |
T |
16: 5,038,312 (GRCm39) |
|
probably null |
Het |
| Bbs1 |
A |
T |
19: 4,940,749 (GRCm39) |
L578Q |
probably damaging |
Het |
| Brd9 |
A |
T |
13: 74,108,433 (GRCm39) |
E589D |
probably damaging |
Het |
| Calr4 |
A |
G |
4: 109,101,442 (GRCm39) |
D108G |
probably benign |
Het |
| Ccdc82 |
A |
G |
9: 13,272,798 (GRCm39) |
D429G |
probably damaging |
Het |
| Cdh22 |
G |
T |
2: 164,988,550 (GRCm39) |
N268K |
probably damaging |
Het |
| Ceacam12 |
G |
A |
7: 17,801,312 (GRCm39) |
G97D |
probably damaging |
Het |
| Clcn1 |
A |
G |
6: 42,291,096 (GRCm39) |
D990G |
probably damaging |
Het |
| Cyp2c40 |
T |
C |
19: 39,801,004 (GRCm39) |
T84A |
probably benign |
Het |
| Dnah7a |
G |
A |
1: 53,472,181 (GRCm39) |
P3529S |
probably damaging |
Het |
| Dnah8 |
G |
A |
17: 30,967,542 (GRCm39) |
D2585N |
probably benign |
Het |
| Efna3 |
GAGCAGCAGCAGCAGCAGCAGC |
GAGCAGCAGCAGCAGCAGC |
3: 89,230,105 (GRCm39) |
|
probably benign |
Het |
| Ehd2 |
G |
A |
7: 15,697,389 (GRCm39) |
Q4* |
probably null |
Het |
| Eml5 |
A |
G |
12: 98,760,715 (GRCm39) |
V1726A |
possibly damaging |
Het |
| Esam |
A |
G |
9: 37,439,544 (GRCm39) |
T10A |
probably benign |
Het |
| Fbxl6 |
A |
G |
15: 76,422,633 (GRCm39) |
L95P |
probably benign |
Het |
| Fbxw18 |
T |
A |
9: 109,505,947 (GRCm39) |
L441F |
probably damaging |
Het |
| Fbxw4 |
A |
G |
19: 45,624,766 (GRCm39) |
S73P |
probably benign |
Het |
| Fndc1 |
T |
A |
17: 7,991,479 (GRCm39) |
H739L |
unknown |
Het |
| Foxp1 |
G |
A |
6: 98,943,037 (GRCm39) |
T237I |
probably damaging |
Het |
| Greb1 |
A |
T |
12: 16,724,771 (GRCm39) |
I1801N |
probably damaging |
Het |
| Hjurp |
GT |
GTT |
1: 88,194,246 (GRCm39) |
|
probably null |
Het |
| Hoxa13 |
G |
T |
6: 52,236,908 (GRCm39) |
N281K |
probably damaging |
Het |
| Hspg2 |
A |
G |
4: 137,296,829 (GRCm39) |
T4328A |
probably damaging |
Het |
| Htr2a |
C |
G |
14: 74,882,474 (GRCm39) |
Y153* |
probably null |
Het |
| Iglv1 |
C |
A |
16: 18,903,844 (GRCm39) |
A92S |
probably damaging |
Het |
| Itih1 |
A |
G |
14: 30,653,152 (GRCm39) |
S759P |
probably damaging |
Het |
| Kctd1 |
G |
T |
18: 15,102,688 (GRCm39) |
S831* |
probably null |
Het |
| Kif20a |
T |
A |
18: 34,761,199 (GRCm39) |
S265T |
probably damaging |
Het |
| Kif22 |
T |
A |
7: 126,630,228 (GRCm39) |
E436V |
possibly damaging |
Het |
| Kif27 |
A |
G |
13: 58,459,051 (GRCm39) |
W927R |
probably damaging |
Het |
| Lcorl |
G |
A |
5: 45,933,832 (GRCm39) |
P66L |
probably damaging |
Het |
| Lct |
A |
G |
1: 128,255,451 (GRCm39) |
L197P |
probably damaging |
Het |
| Lefty1 |
T |
C |
1: 180,762,714 (GRCm39) |
S14P |
unknown |
Het |
| Lnp1 |
A |
G |
16: 56,737,855 (GRCm39) |
S78P |
possibly damaging |
Het |
| Map3k19 |
A |
T |
1: 127,750,569 (GRCm39) |
H927Q |
probably benign |
Het |
| Meiosin |
C |
A |
7: 18,834,814 (GRCm39) |
|
probably benign |
Het |
| Mta3 |
A |
G |
17: 84,099,222 (GRCm39) |
T430A |
probably benign |
Het |
| Muc2 |
G |
T |
7: 141,282,875 (GRCm39) |
C627F |
probably damaging |
Het |
| Nck2 |
T |
A |
1: 43,572,729 (GRCm39) |
M1K |
probably null |
Het |
| Nipal1 |
A |
G |
5: 72,820,898 (GRCm39) |
N131S |
probably damaging |
Het |
| Nlrp9c |
T |
C |
7: 26,077,426 (GRCm39) |
|
probably null |
Het |
| Nr2f2 |
A |
G |
7: 70,007,946 (GRCm39) |
S179P |
probably damaging |
Het |
| Or1j16 |
A |
G |
2: 36,530,063 (GRCm39) |
D4G |
probably benign |
Het |
| Or1j21 |
A |
T |
2: 36,683,980 (GRCm39) |
H244L |
probably damaging |
Het |
| Or9g19 |
A |
T |
2: 85,600,652 (GRCm39) |
N169I |
probably benign |
Het |
| Oxt |
G |
T |
2: 130,418,163 (GRCm39) |
|
probably benign |
Het |
| Pank2 |
T |
A |
2: 131,122,181 (GRCm39) |
Y235* |
probably null |
Het |
| Pear1 |
A |
G |
3: 87,659,440 (GRCm39) |
L798P |
possibly damaging |
Het |
| Pex14 |
T |
C |
4: 149,046,156 (GRCm39) |
H258R |
probably benign |
Het |
| Pmpcb |
A |
G |
5: 21,962,031 (GRCm39) |
I487V |
probably benign |
Het |
| Ppie |
T |
C |
4: 123,031,362 (GRCm39) |
E44G |
probably benign |
Het |
| Ppp1r9a |
A |
T |
6: 4,905,639 (GRCm39) |
R65* |
probably null |
Het |
| Ralgapb |
T |
C |
2: 158,288,075 (GRCm39) |
S371P |
probably damaging |
Het |
| Ros1 |
T |
C |
10: 51,977,881 (GRCm39) |
H1455R |
probably benign |
Het |
| Sacs |
C |
A |
14: 61,450,275 (GRCm39) |
T4107K |
possibly damaging |
Het |
| Sec24a |
G |
A |
11: 51,622,718 (GRCm39) |
T386M |
probably damaging |
Het |
| Slc10a4 |
A |
T |
5: 73,169,593 (GRCm39) |
Y207F |
possibly damaging |
Het |
| Slc30a10 |
T |
C |
1: 185,187,508 (GRCm39) |
L83P |
probably damaging |
Het |
| Slc38a9 |
T |
A |
13: 112,840,093 (GRCm39) |
L324* |
probably null |
Het |
| Slc7a9 |
A |
T |
7: 35,165,277 (GRCm39) |
Q474L |
probably damaging |
Het |
| Smc5 |
C |
A |
19: 23,191,534 (GRCm39) |
V875L |
possibly damaging |
Het |
| Snap91 |
T |
C |
9: 86,707,053 (GRCm39) |
R246G |
probably damaging |
Het |
| Sned1 |
A |
G |
1: 93,203,196 (GRCm39) |
|
probably null |
Het |
| Spink14 |
G |
A |
18: 44,164,938 (GRCm39) |
G85E |
probably benign |
Het |
| Srsf11 |
C |
T |
3: 157,728,981 (GRCm39) |
|
probably benign |
Het |
| St13 |
A |
G |
15: 81,283,506 (GRCm39) |
|
probably null |
Het |
| Stk10 |
A |
G |
11: 32,553,761 (GRCm39) |
M593V |
possibly damaging |
Het |
| Tafa1 |
A |
G |
6: 96,092,721 (GRCm39) |
H35R |
probably benign |
Het |
| Tex21 |
C |
A |
12: 76,245,707 (GRCm39) |
A530S |
probably benign |
Het |
| Tln2 |
T |
A |
9: 67,131,363 (GRCm39) |
K1394N |
probably damaging |
Het |
| Trhr2 |
C |
A |
8: 123,084,118 (GRCm39) |
R294L |
probably damaging |
Het |
| Unc79 |
A |
T |
12: 103,149,708 (GRCm39) |
I2408F |
probably damaging |
Het |
| Wdr24 |
T |
C |
17: 26,045,552 (GRCm39) |
L429P |
probably damaging |
Het |
| Wwp2 |
T |
A |
8: 108,210,039 (GRCm39) |
I139N |
possibly damaging |
Het |
| Zfp111 |
G |
A |
7: 23,897,554 (GRCm39) |
R686C |
unknown |
Het |
| Zfp268 |
A |
T |
4: 145,350,811 (GRCm39) |
|
probably benign |
Het |
| Zyg11a |
A |
G |
4: 108,046,878 (GRCm39) |
V532A |
probably benign |
Het |
|
| Other mutations in Myh13 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00497:Myh13
|
APN |
11 |
67,233,314 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL00808:Myh13
|
APN |
11 |
67,225,830 (GRCm39) |
critical splice donor site |
probably null |
|
|
IGL00822:Myh13
|
APN |
11 |
67,252,154 (GRCm39) |
missense |
probably damaging |
0.98 |
|
IGL00823:Myh13
|
APN |
11 |
67,246,773 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL00945:Myh13
|
APN |
11 |
67,238,832 (GRCm39) |
missense |
probably null |
1.00 |
|
IGL01414:Myh13
|
APN |
11 |
67,233,298 (GRCm39) |
missense |
probably benign |
0.02 |
|
IGL01482:Myh13
|
APN |
11 |
67,242,894 (GRCm39) |
missense |
probably benign |
|
|
IGL01523:Myh13
|
APN |
11 |
67,238,769 (GRCm39) |
missense |
possibly damaging |
0.73 |
|
IGL01723:Myh13
|
APN |
11 |
67,260,045 (GRCm39) |
unclassified |
probably benign |
|
|
IGL01997:Myh13
|
APN |
11 |
67,257,992 (GRCm39) |
missense |
probably benign |
0.14 |
|
IGL02369:Myh13
|
APN |
11 |
67,251,100 (GRCm39) |
unclassified |
probably benign |
|
|
IGL02478:Myh13
|
APN |
11 |
67,260,204 (GRCm39) |
missense |
probably benign |
|
|
IGL02663:Myh13
|
APN |
11 |
67,245,753 (GRCm39) |
nonsense |
probably null |
|
|
IGL02851:Myh13
|
APN |
11 |
67,239,742 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
IGL02863:Myh13
|
APN |
11 |
67,223,367 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02929:Myh13
|
APN |
11 |
67,257,991 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02979:Myh13
|
APN |
11 |
67,225,788 (GRCm39) |
missense |
possibly damaging |
0.72 |
|
IGL03065:Myh13
|
APN |
11 |
67,235,679 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL03214:Myh13
|
APN |
11 |
67,244,411 (GRCm39) |
missense |
possibly damaging |
0.79 |
|
IGL03223:Myh13
|
APN |
11 |
67,241,068 (GRCm39) |
missense |
probably benign |
0.39 |
|
IGL03231:Myh13
|
APN |
11 |
67,242,817 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
IGL03407:Myh13
|
APN |
11 |
67,242,978 (GRCm39) |
missense |
probably damaging |
1.00 |
|
3-1:Myh13
|
UTSW |
11 |
67,242,777 (GRCm39) |
splice site |
probably benign |
|
|
P0042:Myh13
|
UTSW |
11 |
67,225,817 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0047:Myh13
|
UTSW |
11 |
67,258,063 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0047:Myh13
|
UTSW |
11 |
67,258,063 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0379:Myh13
|
UTSW |
11 |
67,260,121 (GRCm39) |
unclassified |
probably benign |
|
|
R0496:Myh13
|
UTSW |
11 |
67,239,641 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0584:Myh13
|
UTSW |
11 |
67,251,200 (GRCm39) |
nonsense |
probably null |
|
|
R0595:Myh13
|
UTSW |
11 |
67,235,672 (GRCm39) |
missense |
probably benign |
0.03 |
|
R0621:Myh13
|
UTSW |
11 |
67,232,058 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R0834:Myh13
|
UTSW |
11 |
67,240,436 (GRCm39) |
missense |
possibly damaging |
0.88 |
|
R0893:Myh13
|
UTSW |
11 |
67,225,427 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0964:Myh13
|
UTSW |
11 |
67,235,828 (GRCm39) |
missense |
probably benign |
0.02 |
|
R0973:Myh13
|
UTSW |
11 |
67,223,346 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0973:Myh13
|
UTSW |
11 |
67,223,346 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0974:Myh13
|
UTSW |
11 |
67,223,346 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1028:Myh13
|
UTSW |
11 |
67,247,007 (GRCm39) |
missense |
possibly damaging |
0.71 |
|
R1112:Myh13
|
UTSW |
11 |
67,245,576 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1283:Myh13
|
UTSW |
11 |
67,261,747 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1288:Myh13
|
UTSW |
11 |
67,244,544 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1386:Myh13
|
UTSW |
11 |
67,261,776 (GRCm39) |
missense |
possibly damaging |
0.79 |
|
R1457:Myh13
|
UTSW |
11 |
67,221,872 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R1503:Myh13
|
UTSW |
11 |
67,244,500 (GRCm39) |
missense |
probably benign |
0.43 |
|
R1574:Myh13
|
UTSW |
11 |
67,253,407 (GRCm39) |
unclassified |
probably benign |
|
|
R1673:Myh13
|
UTSW |
11 |
67,242,945 (GRCm39) |
missense |
possibly damaging |
0.79 |
|
R1693:Myh13
|
UTSW |
11 |
67,232,310 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R1763:Myh13
|
UTSW |
11 |
67,225,402 (GRCm39) |
missense |
probably benign |
|
|
R2029:Myh13
|
UTSW |
11 |
67,252,115 (GRCm39) |
missense |
probably benign |
0.03 |
|
R2030:Myh13
|
UTSW |
11 |
67,241,064 (GRCm39) |
missense |
probably benign |
|
|
R2247:Myh13
|
UTSW |
11 |
67,225,384 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R2393:Myh13
|
UTSW |
11 |
67,231,184 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R2395:Myh13
|
UTSW |
11 |
67,255,748 (GRCm39) |
missense |
probably benign |
0.12 |
|
R2884:Myh13
|
UTSW |
11 |
67,228,469 (GRCm39) |
missense |
probably benign |
0.27 |
|
R3696:Myh13
|
UTSW |
11 |
67,235,870 (GRCm39) |
missense |
possibly damaging |
0.55 |
|
R3786:Myh13
|
UTSW |
11 |
67,218,014 (GRCm39) |
missense |
probably benign |
0.01 |
|
R3875:Myh13
|
UTSW |
11 |
67,249,020 (GRCm39) |
missense |
probably benign |
0.26 |
|
R3918:Myh13
|
UTSW |
11 |
67,220,064 (GRCm39) |
missense |
probably benign |
0.00 |
|
R4061:Myh13
|
UTSW |
11 |
67,221,715 (GRCm39) |
missense |
possibly damaging |
0.71 |
|
R4160:Myh13
|
UTSW |
11 |
67,255,636 (GRCm39) |
intron |
probably benign |
|
|
R4183:Myh13
|
UTSW |
11 |
67,240,436 (GRCm39) |
missense |
possibly damaging |
0.88 |
|
R4392:Myh13
|
UTSW |
11 |
67,235,707 (GRCm39) |
splice site |
probably null |
|
|
R4639:Myh13
|
UTSW |
11 |
67,232,377 (GRCm39) |
missense |
possibly damaging |
0.91 |
|
R4670:Myh13
|
UTSW |
11 |
67,255,564 (GRCm39) |
nonsense |
probably null |
|
|
R4783:Myh13
|
UTSW |
11 |
67,232,096 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4877:Myh13
|
UTSW |
11 |
67,228,477 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5250:Myh13
|
UTSW |
11 |
67,218,085 (GRCm39) |
nonsense |
probably null |
|
|
R5278:Myh13
|
UTSW |
11 |
67,225,390 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5371:Myh13
|
UTSW |
11 |
67,235,616 (GRCm39) |
splice site |
probably null |
|
|
R5479:Myh13
|
UTSW |
11 |
67,239,648 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R5510:Myh13
|
UTSW |
11 |
67,228,549 (GRCm39) |
missense |
probably benign |
0.05 |
|
R5690:Myh13
|
UTSW |
11 |
67,220,101 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5797:Myh13
|
UTSW |
11 |
67,225,828 (GRCm39) |
missense |
possibly damaging |
0.66 |
|
R5823:Myh13
|
UTSW |
11 |
67,251,294 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5877:Myh13
|
UTSW |
11 |
67,244,484 (GRCm39) |
missense |
possibly damaging |
0.78 |
|
R6041:Myh13
|
UTSW |
11 |
67,255,556 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6244:Myh13
|
UTSW |
11 |
67,253,327 (GRCm39) |
missense |
probably benign |
0.00 |
|
R6454:Myh13
|
UTSW |
11 |
67,241,191 (GRCm39) |
missense |
probably benign |
0.03 |
|
R6617:Myh13
|
UTSW |
11 |
67,252,226 (GRCm39) |
missense |
probably benign |
0.00 |
|
R6707:Myh13
|
UTSW |
11 |
67,241,086 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6747:Myh13
|
UTSW |
11 |
67,241,245 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R6823:Myh13
|
UTSW |
11 |
67,246,984 (GRCm39) |
missense |
probably benign |
|
|
R6911:Myh13
|
UTSW |
11 |
67,245,753 (GRCm39) |
nonsense |
probably null |
|
|
R6997:Myh13
|
UTSW |
11 |
67,217,980 (GRCm39) |
nonsense |
probably null |
|
|
R7033:Myh13
|
UTSW |
11 |
67,260,142 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R7145:Myh13
|
UTSW |
11 |
67,245,566 (GRCm39) |
missense |
probably benign |
0.08 |
|
R7232:Myh13
|
UTSW |
11 |
67,239,672 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7428:Myh13
|
UTSW |
11 |
67,223,390 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7448:Myh13
|
UTSW |
11 |
67,255,286 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
R7474:Myh13
|
UTSW |
11 |
67,258,537 (GRCm39) |
missense |
|
|
|
R7474:Myh13
|
UTSW |
11 |
67,217,990 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R7766:Myh13
|
UTSW |
11 |
67,249,155 (GRCm39) |
missense |
probably benign |
0.37 |
|
R7809:Myh13
|
UTSW |
11 |
67,241,167 (GRCm39) |
missense |
probably benign |
0.14 |
|
R7813:Myh13
|
UTSW |
11 |
67,218,056 (GRCm39) |
missense |
probably benign |
0.27 |
|
R7953:Myh13
|
UTSW |
11 |
67,231,206 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8085:Myh13
|
UTSW |
11 |
67,225,613 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8397:Myh13
|
UTSW |
11 |
67,241,113 (GRCm39) |
missense |
possibly damaging |
0.62 |
|
R8434:Myh13
|
UTSW |
11 |
67,254,011 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
R8490:Myh13
|
UTSW |
11 |
67,255,351 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R8676:Myh13
|
UTSW |
11 |
67,233,311 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8681:Myh13
|
UTSW |
11 |
67,242,960 (GRCm39) |
missense |
possibly damaging |
0.49 |
|
R8777:Myh13
|
UTSW |
11 |
67,252,161 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R8777-TAIL:Myh13
|
UTSW |
11 |
67,252,161 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R8965:Myh13
|
UTSW |
11 |
67,255,432 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9088:Myh13
|
UTSW |
11 |
67,242,885 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9151:Myh13
|
UTSW |
11 |
67,252,149 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9154:Myh13
|
UTSW |
11 |
67,253,318 (GRCm39) |
missense |
probably benign |
|
|
R9182:Myh13
|
UTSW |
11 |
67,228,579 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9332:Myh13
|
UTSW |
11 |
67,254,109 (GRCm39) |
missense |
possibly damaging |
0.57 |
|
R9393:Myh13
|
UTSW |
11 |
67,242,894 (GRCm39) |
missense |
probably benign |
|
|
R9446:Myh13
|
UTSW |
11 |
67,255,325 (GRCm39) |
missense |
probably benign |
0.01 |
|
R9474:Myh13
|
UTSW |
11 |
67,255,712 (GRCm39) |
missense |
|
|
|
R9690:Myh13
|
UTSW |
11 |
67,249,194 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9761:Myh13
|
UTSW |
11 |
67,251,294 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9778:Myh13
|
UTSW |
11 |
67,249,016 (GRCm39) |
missense |
probably damaging |
0.98 |
|
Z1176:Myh13
|
UTSW |
11 |
67,220,121 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
Z1177:Myh13
|
UTSW |
11 |
67,255,417 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
Z1177:Myh13
|
UTSW |
11 |
67,241,278 (GRCm39) |
missense |
possibly damaging |
0.55 |
|
| Predicted Primers |
PCR Primer
(F):5'- AAAGAGGTACCTGGAAGCCC -3'
(R):5'- TGCAGCTGTAGACTGAGGAC -3'
Sequencing Primer
(F):5'- GTACCTGGAAGCCCCCAAGATATC -3'
(R):5'- AGACTGAGGACTTGCTCATCATCG -3'
|
| Posted On |
2017-10-10 |
Incidental Mutation