Mutagenetix > Incidental Mutation

Incidental Mutation 'R6145:Igsf10'

488795

Institutional Source

Beutler Lab

Gene Symbol

Igsf10

Ensembl Gene

ENSMUSG00000036334

Gene Name

immunoglobulin superfamily, member 10

Synonyms

Adlican2, CMF608, 6530405F15Rik

MMRRC Submission

044292-MU

Accession Numbers

Essential gene?

Probably non essential (E-score: 0.193) question?

Stock #

R6145 (G1)

Quality Score

225.009

Status

Not validated

Chromosome

Chromosomal Location

59316735-59344394 bp(-) (GRCm38)

Type of Mutation

missense

DNA Base Change (assembly)

T to A at 59331656 bp (GRCm38)

Zygosity

Heterozygous

Amino Acid Change

Tyrosine to Phenylalanine at position 368 (Y368F)

Ref Sequence

ENSEMBL: ENSMUSP00000141391 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000039419] [ENSMUST00000193455] [ENSMUST00000194546]

AlphaFold

Q3V1M1

Predicted Effect

possibly damaging
Transcript: ENSMUST00000039419
AA Change: Y368F

PolyPhen 2 Score 0.834 (Sensitivity: 0.84; Specificity: 0.93)

SMART Domains

Protein: ENSMUSP00000037246
Gene: ENSMUSG00000036334
AA Change: Y368F

Domain	Start	End	E-Value	Type
signal peptide	1	25	N/A	INTRINSIC
LRRNT	28	61	3.24e-4	SMART
LRR	57	79	9.24e1	SMART
LRR	80	103	2.02e-1	SMART
LRR	104	127	7.16e0	SMART
LRR_TYP	128	151	1.2e-3	SMART
LRR	152	175	1.25e-1	SMART
LRR	188	207	2.33e2	SMART
LRRCT	219	280	4.19e-4	SMART
IGc2	488	558	2.34e-4	SMART
IGc2	586	652	7.88e-11	SMART
low complexity region	917	930	N/A	INTRINSIC
low complexity region	1175	1185	N/A	INTRINSIC
low complexity region	1245	1263	N/A	INTRINSIC
low complexity region	1311	1321	N/A	INTRINSIC
low complexity region	1449	1465	N/A	INTRINSIC
IGc2	1632	1701	7.69e-14	SMART
IGc2	1729	1798	5.07e-14	SMART
IGc2	1826	1895	2.19e-9	SMART
IGc2	1925	1994	4.59e-12	SMART
IGc2	2022	2097	1.33e-8	SMART
IGc2	2125	2191	2.96e-15	SMART
IGc2	2223	2291	2.03e-4	SMART
IGc2	2321	2389	9.99e-13	SMART
IGc2	2416	2484	3.03e-12	SMART
IGc2	2512	2583	7.76e-10	SMART

Predicted Effect

possibly damaging
Transcript: ENSMUST00000193455
AA Change: Y368F

PolyPhen 2 Score 0.834 (Sensitivity: 0.84; Specificity: 0.93)

SMART Domains

Protein: ENSMUSP00000141971
Gene: ENSMUSG00000036334
AA Change: Y368F

Domain	Start	End	E-Value	Type
signal peptide	1	25	N/A	INTRINSIC
LRRNT	28	61	3.24e-4	SMART
LRR	57	79	9.24e1	SMART
LRR	80	103	2.02e-1	SMART
LRR	104	127	7.16e0	SMART
LRR_TYP	128	151	1.2e-3	SMART
LRR	152	175	1.25e-1	SMART
LRR	188	207	2.33e2	SMART
LRRCT	219	280	4.19e-4	SMART
IGc2	488	558	2.34e-4	SMART
IGc2	586	652	7.88e-11	SMART
low complexity region	917	930	N/A	INTRINSIC
low complexity region	1175	1185	N/A	INTRINSIC
low complexity region	1245	1263	N/A	INTRINSIC
low complexity region	1311	1321	N/A	INTRINSIC
low complexity region	1449	1465	N/A	INTRINSIC
IGc2	1632	1701	7.69e-14	SMART
IGc2	1729	1798	5.07e-14	SMART
IGc2	1826	1895	2.19e-9	SMART
IGc2	1925	1994	4.59e-12	SMART
IGc2	2022	2097	1.33e-8	SMART
IGc2	2125	2191	2.96e-15	SMART
IGc2	2223	2291	2.03e-4	SMART
IGc2	2321	2389	9.99e-13	SMART
IGc2	2416	2484	3.03e-12	SMART
IGc2	2512	2583	7.76e-10	SMART

Predicted Effect

possibly damaging
Transcript: ENSMUST00000194546
AA Change: Y368F

PolyPhen 2 Score 0.834 (Sensitivity: 0.84; Specificity: 0.93)

SMART Domains

Protein: ENSMUSP00000141391
Gene: ENSMUSG00000036334
AA Change: Y368F

Domain	Start	End	E-Value	Type
signal peptide	1	25	N/A	INTRINSIC
LRRNT	28	61	3.24e-4	SMART
LRR	57	79	9.24e1	SMART
LRR	80	103	2.02e-1	SMART
LRR	104	127	7.16e0	SMART
LRR_TYP	128	151	1.2e-3	SMART
LRR	152	175	1.25e-1	SMART
LRR	188	207	2.33e2	SMART
LRRCT	219	280	4.19e-4	SMART
IGc2	488	558	2.34e-4	SMART
IGc2	586	652	7.88e-11	SMART
low complexity region	917	930	N/A	INTRINSIC
low complexity region	1175	1185	N/A	INTRINSIC
low complexity region	1245	1263	N/A	INTRINSIC
low complexity region	1311	1321	N/A	INTRINSIC
low complexity region	1449	1465	N/A	INTRINSIC
IGc2	1632	1701	7.69e-14	SMART
IGc2	1729	1798	5.07e-14	SMART
IGc2	1826	1895	2.19e-9	SMART
IGc2	1925	1994	4.59e-12	SMART
IGc2	2022	2097	1.33e-8	SMART
IGc2	2125	2191	2.96e-15	SMART
IGc2	2223	2291	2.03e-4	SMART
IGc2	2321	2389	9.99e-13	SMART
IGc2	2416	2484	3.03e-12	SMART
IGc2	2512	2583	7.76e-10	SMART

Coding Region Coverage

1x: 99.9%
3x: 99.5%
10x: 98.0%
20x: 95.0%

Validation Efficiency

Allele List at MGI

All alleles(2) : Targeted, other(2)

Other mutations in this stock

Total: 77 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
2810459M11Rik	T	A	1: 86,052,942 (GRCm38)		probably null	Het
Abca8b	A	G	11: 109,973,808 (GRCm38)	V316A	probably benign	Het
Acad10	A	T	5: 121,622,033 (GRCm38)	V999D	probably damaging	Het
Acot8	A	G	2: 164,803,065 (GRCm38)	V66A	probably benign	Het
Ankrd11	T	C	8: 122,892,661 (GRCm38)	H1484R	probably damaging	Het
Anxa6	A	G	11: 54,994,904 (GRCm38)	F405S	probably damaging	Het
Asmt	G	A	X: 170,674,663 (GRCm38)	V101I	probably damaging	Het
Atp1a2	C	T	1: 172,287,238 (GRCm38)	V327I	probably damaging	Het
Brdt	A	G	5: 107,377,999 (GRCm38)	E906G	possibly damaging	Het
Cacna1g	A	T	11: 94,462,261 (GRCm38)	C313S	probably damaging	Het
Camk2d	T	C	3: 126,805,858 (GRCm38)	I329T	probably benign	Het
Cavin4	A	T	4: 48,663,794 (GRCm38)	H58L	probably damaging	Het
Ccdc78	C	A	17: 25,789,065 (GRCm38)	P317T	probably benign	Het
Cdc16	T	G	8: 13,767,573 (GRCm38)	Y295D	possibly damaging	Het
Cdyl2	T	A	8: 116,594,978 (GRCm38)	N270I	probably damaging	Het
Cfap221	T	A	1: 119,984,816 (GRCm38)	I114F	possibly damaging	Het
Dmxl1	A	G	18: 49,912,766 (GRCm38)	E2414G	possibly damaging	Het
Dnaaf9	T	C	2: 130,778,473 (GRCm38)	I247V	probably benign	Het
Dnah1	C	A	14: 31,300,970 (GRCm38)	R1070L	probably benign	Het
Dnah14	T	C	1: 181,666,417 (GRCm38)	S1713P	probably benign	Het
Dock10	C	A	1: 80,575,904 (GRCm38)	G602*	probably null	Het
Ep400	A	T	5: 110,756,703 (GRCm38)	V10D	possibly damaging	Het
Epas1	T	C	17: 86,829,429 (GRCm38)	C807R	probably benign	Het
Esrrb	C	T	12: 86,505,899 (GRCm38)	P200L	probably benign	Het
Fbxw26	T	C	9: 109,732,623 (GRCm38)	I168V	probably benign	Het
Fsip2	A	T	2: 82,993,768 (GRCm38)	H6615L	possibly damaging	Het
Galk2	A	T	2: 125,946,842 (GRCm38)	Q272L	possibly damaging	Het
Gas7	A	C	11: 67,629,612 (GRCm38)	T43P	probably damaging	Het
Gm5134	A	T	10: 75,995,839 (GRCm38)	I371F	probably damaging	Het
Gpr31b	C	T	17: 13,051,379 (GRCm38)	R301Q	possibly damaging	Het
Grk1	T	A	8: 13,405,765 (GRCm38)	Y216*	probably null	Het
Grm5	T	A	7: 88,026,601 (GRCm38)	M441K	probably damaging	Het
Heatr6	A	G	11: 83,766,136 (GRCm38)	E408G	probably damaging	Het
Hoxc9	G	T	15: 102,983,959 (GRCm38)	K201N	probably damaging	Het
Il2ra	A	T	2: 11,680,246 (GRCm38)	D131V	probably damaging	Het
Imp4	A	G	1: 34,440,096 (GRCm38)	E19G	probably benign	Het
Kcnk18	T	C	19: 59,235,607 (GRCm38)	*395Q	probably null	Het
Kdm6b	A	T	11: 69,405,026 (GRCm38)	L805Q	unknown	Het
Lgr4	T	A	2: 110,007,243 (GRCm38)	L427*	probably null	Het
Myt1l	G	A	12: 29,832,381 (GRCm38)	S525N	unknown	Het
Nasp	G	A	4: 116,611,077 (GRCm38)	T237I	probably benign	Het
Nell2	G	T	15: 95,473,561 (GRCm38)	Q98K	probably damaging	Het
Nfasc	C	T	1: 132,634,717 (GRCm38)	G107R	probably damaging	Het
Nsun4	A	G	4: 116,040,206 (GRCm38)	S203P	probably damaging	Het
Or1m1	T	G	9: 18,755,569 (GRCm38)	D22A	probably benign	Het
Or7g35	T	C	9: 19,584,888 (GRCm38)	V117A	probably benign	Het
Otogl	G	A	10: 107,777,117 (GRCm38)		silent	Het
Pde10a	T	C	17: 8,929,117 (GRCm38)	V366A	probably damaging	Het
Pdxk	T	A	10: 78,443,791 (GRCm38)	D250V	probably benign	Het
Pih1d1	T	A	7: 45,159,044 (GRCm38)	I179N	probably damaging	Het
Plaa	T	A	4: 94,583,992 (GRCm38)	I294F	probably damaging	Het
Pmel	C	A	10: 128,715,935 (GRCm38)	P213T	probably damaging	Het
Pom121l2	A	T	13: 21,982,302 (GRCm38)	R248*	probably null	Het
Pou2f1	T	C	1: 165,875,433 (GRCm38)		probably benign	Het
Ppm1j	G	A	3: 104,781,379 (GRCm38)	R98H	probably damaging	Het
Prkdc	C	T	16: 15,772,073 (GRCm38)	P2600L	probably damaging	Het
Prom1	T	C	5: 44,029,649 (GRCm38)	N422S	probably benign	Het
Pspn	C	T	17: 56,999,467 (GRCm38)	C154Y	probably damaging	Het
Ptdss1	T	C	13: 66,972,637 (GRCm38)		probably null	Het
Rapgef1	A	G	2: 29,736,666 (GRCm38)	Y993C	probably damaging	Het
Scrn2	A	C	11: 97,032,853 (GRCm38)	T219P	probably benign	Het
Sec23ip	T	G	7: 128,778,484 (GRCm38)	S874R	probably damaging	Het
Septin4	G	A	11: 87,585,246 (GRCm38)		probably null	Het
Slc15a3	C	T	19: 10,857,251 (GRCm38)	L499F	probably damaging	Het
Spaca9	G	A	2: 28,693,781 (GRCm38)	R64W	probably damaging	Het
Sra1	A	G	18: 36,667,575 (GRCm38)	M193T	probably damaging	Het
Srsf4	G	T	4: 131,900,294 (GRCm38)		probably benign	Het
Syne1	T	C	10: 5,052,750 (GRCm38)	D8055G	probably damaging	Het
Syne4	T	A	7: 30,316,563 (GRCm38)		probably null	Het
Tbc1d24	C	A	17: 24,208,229 (GRCm38)	G253V	probably damaging	Het
Tbck	T	A	3: 132,732,215 (GRCm38)	I467N	probably damaging	Het
Tln1	T	A	4: 43,538,030 (GRCm38)	M1857L	possibly damaging	Het
Ttll2	T	C	17: 7,351,632 (GRCm38)	R299G	probably benign	Het
Ugt2b36	T	G	5: 87,066,213 (GRCm38)	E524A	probably benign	Het
Vmn2r124	C	T	17: 18,062,851 (GRCm38)	T269I	probably benign	Het
Vmn2r4	A	G	3: 64,406,943 (GRCm38)	F206L	probably benign	Het
Zfp346	A	G	13: 55,115,574 (GRCm38)	K156R	probably damaging	Het

Other mutations in Igsf10

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00773:Igsf10	APN	3	59,331,539 (GRCm38)	missense	probably benign	0.03
IGL00790:Igsf10	APN	3	59,319,517 (GRCm38)	missense	probably damaging	1.00
IGL00916:Igsf10	APN	3	59,331,127 (GRCm38)	missense	probably damaging	0.97
IGL00928:Igsf10	APN	3	59,330,597 (GRCm38)	missense	probably benign	0.00
IGL01066:Igsf10	APN	3	59,327,782 (GRCm38)	critical splice donor site	probably null
IGL01107:Igsf10	APN	3	59,331,524 (GRCm38)	missense	probably damaging	1.00
IGL01420:Igsf10	APN	3	59,319,650 (GRCm38)	missense	probably benign	0.02
IGL01533:Igsf10	APN	3	59,319,230 (GRCm38)	missense	probably damaging	0.98
IGL01537:Igsf10	APN	3	59,330,031 (GRCm38)	missense	probably benign	0.00
IGL01676:Igsf10	APN	3	59,329,335 (GRCm38)	missense	probably benign	0.17
IGL01676:Igsf10	APN	3	59,326,011 (GRCm38)	missense	probably benign	0.06
IGL01960:Igsf10	APN	3	59,318,737 (GRCm38)	missense	probably benign	0.00
IGL02123:Igsf10	APN	3	59,318,660 (GRCm38)	missense	probably damaging	0.97
IGL02198:Igsf10	APN	3	59,325,978 (GRCm38)	missense	possibly damaging	0.95
IGL02268:Igsf10	APN	3	59,331,152 (GRCm38)	nonsense	probably null
IGL02313:Igsf10	APN	3	59,330,690 (GRCm38)	missense	probably benign	0.01
IGL02368:Igsf10	APN	3	59,328,231 (GRCm38)	missense	probably benign
IGL02494:Igsf10	APN	3	59,328,006 (GRCm38)	missense	probably damaging	0.98
IGL02549:Igsf10	APN	3	59,329,241 (GRCm38)	missense	probably benign	0.03
IGL02616:Igsf10	APN	3	59,318,606 (GRCm38)	missense	probably benign	0.06
IGL02957:Igsf10	APN	3	59,330,864 (GRCm38)	missense	probably damaging	1.00
IGL03067:Igsf10	APN	3	59,318,918 (GRCm38)	missense	probably benign	0.25
IGL03104:Igsf10	APN	3	59,319,484 (GRCm38)	missense	probably damaging	1.00
IGL03124:Igsf10	APN	3	59,319,665 (GRCm38)	missense	probably benign	0.01
IGL03212:Igsf10	APN	3	59,328,165 (GRCm38)	missense	probably benign	0.09
IGL03347:Igsf10	APN	3	59,331,900 (GRCm38)	missense	possibly damaging	0.94
IGL03357:Igsf10	APN	3	59,336,211 (GRCm38)	missense	probably benign	0.35
F6893:Igsf10	UTSW	3	59,331,060 (GRCm38)	missense	probably damaging	1.00
FR4449:Igsf10	UTSW	3	59,319,110 (GRCm38)	missense	probably damaging	1.00
PIT1430001:Igsf10	UTSW	3	59,328,158 (GRCm38)	missense	probably benign	0.06
PIT4402001:Igsf10	UTSW	3	59,325,579 (GRCm38)	missense	probably benign	0.00
PIT4810001:Igsf10	UTSW	3	59,318,482 (GRCm38)	missense	probably damaging	1.00
R0068:Igsf10	UTSW	3	59,330,624 (GRCm38)	missense	probably damaging	0.98
R0095:Igsf10	UTSW	3	59,331,196 (GRCm38)	nonsense	probably null
R0095:Igsf10	UTSW	3	59,331,196 (GRCm38)	nonsense	probably null
R0112:Igsf10	UTSW	3	59,326,008 (GRCm38)	missense	probably benign	0.00
R0141:Igsf10	UTSW	3	59,330,832 (GRCm38)	missense	probably damaging	1.00
R0538:Igsf10	UTSW	3	59,320,106 (GRCm38)	missense	probably damaging	0.99
R0551:Igsf10	UTSW	3	59,328,668 (GRCm38)	missense	probably benign	0.01
R0556:Igsf10	UTSW	3	59,328,875 (GRCm38)	missense	probably benign	0.02
R0582:Igsf10	UTSW	3	59,319,767 (GRCm38)	missense	probably benign	0.00
R0630:Igsf10	UTSW	3	59,326,062 (GRCm38)	missense	probably damaging	1.00
R0675:Igsf10	UTSW	3	59,328,594 (GRCm38)	missense	probably benign	0.14
R0948:Igsf10	UTSW	3	59,331,104 (GRCm38)	missense	probably damaging	1.00
R1252:Igsf10	UTSW	3	59,331,848 (GRCm38)	missense	probably benign	0.03
R1412:Igsf10	UTSW	3	59,327,775 (GRCm38)	splice site	probably benign
R1473:Igsf10	UTSW	3	59,318,767 (GRCm38)	missense	probably damaging	1.00
R1585:Igsf10	UTSW	3	59,330,417 (GRCm38)	missense	probably damaging	1.00
R1650:Igsf10	UTSW	3	59,326,162 (GRCm38)	missense	probably damaging	1.00
R1660:Igsf10	UTSW	3	59,331,285 (GRCm38)	missense	probably damaging	1.00
R1671:Igsf10	UTSW	3	59,328,500 (GRCm38)	nonsense	probably null
R1748:Igsf10	UTSW	3	59,319,093 (GRCm38)	missense	probably damaging	1.00
R1758:Igsf10	UTSW	3	59,329,196 (GRCm38)	missense	probably benign	0.09
R1856:Igsf10	UTSW	3	59,331,272 (GRCm38)	missense	possibly damaging	0.63
R1912:Igsf10	UTSW	3	59,329,572 (GRCm38)	missense	probably benign	0.40
R2148:Igsf10	UTSW	3	59,336,577 (GRCm38)	missense	possibly damaging	0.77
R2155:Igsf10	UTSW	3	59,331,680 (GRCm38)	missense	probably damaging	1.00
R2509:Igsf10	UTSW	3	59,331,866 (GRCm38)	missense	probably damaging	1.00
R2511:Igsf10	UTSW	3	59,331,866 (GRCm38)	missense	probably damaging	1.00
R2680:Igsf10	UTSW	3	59,325,454 (GRCm38)	missense	probably benign	0.14
R2913:Igsf10	UTSW	3	59,331,736 (GRCm38)	missense	possibly damaging	0.70
R2927:Igsf10	UTSW	3	59,329,427 (GRCm38)	missense	probably benign
R3547:Igsf10	UTSW	3	59,336,514 (GRCm38)	missense	probably damaging	1.00
R3547:Igsf10	UTSW	3	59,330,541 (GRCm38)	missense	probably benign	0.02
R3548:Igsf10	UTSW	3	59,336,514 (GRCm38)	missense	probably damaging	1.00
R3620:Igsf10	UTSW	3	59,336,331 (GRCm38)	missense	probably damaging	1.00
R3732:Igsf10	UTSW	3	59,325,714 (GRCm38)	missense	probably benign	0.29
R3743:Igsf10	UTSW	3	59,326,125 (GRCm38)	missense	possibly damaging	0.69
R3973:Igsf10	UTSW	3	59,331,924 (GRCm38)	missense	probably damaging	1.00
R4005:Igsf10	UTSW	3	59,328,560 (GRCm38)	missense	probably benign	0.00
R4184:Igsf10	UTSW	3	59,319,731 (GRCm38)	missense	probably damaging	1.00
R4302:Igsf10	UTSW	3	59,318,750 (GRCm38)	missense	probably damaging	1.00
R4404:Igsf10	UTSW	3	59,329,551 (GRCm38)	missense	probably benign	0.04
R4575:Igsf10	UTSW	3	59,330,100 (GRCm38)	missense	probably benign
R4676:Igsf10	UTSW	3	59,325,949 (GRCm38)	missense	probably benign	0.23
R4700:Igsf10	UTSW	3	59,320,330 (GRCm38)	missense	probably damaging	0.99
R4765:Igsf10	UTSW	3	59,329,705 (GRCm38)	missense	probably benign	0.01
R4986:Igsf10	UTSW	3	59,328,606 (GRCm38)	missense	probably benign	0.24
R5012:Igsf10	UTSW	3	59,318,722 (GRCm38)	missense	probably damaging	1.00
R5070:Igsf10	UTSW	3	59,328,293 (GRCm38)	missense	probably benign	0.02
R5083:Igsf10	UTSW	3	59,326,273 (GRCm38)	missense	probably damaging	1.00
R5336:Igsf10	UTSW	3	59,320,132 (GRCm38)	missense	probably damaging	1.00
R5462:Igsf10	UTSW	3	59,325,754 (GRCm38)	missense	probably damaging	1.00
R5648:Igsf10	UTSW	3	59,328,153 (GRCm38)	missense	probably benign	0.01
R5810:Igsf10	UTSW	3	59,319,071 (GRCm38)	missense	probably damaging	1.00
R5871:Igsf10	UTSW	3	59,330,411 (GRCm38)	missense	possibly damaging	0.83
R5880:Igsf10	UTSW	3	59,330,831 (GRCm38)	missense	probably damaging	1.00
R5935:Igsf10	UTSW	3	59,328,157 (GRCm38)	missense	probably benign	0.12
R5979:Igsf10	UTSW	3	59,336,473 (GRCm38)	missense	probably damaging	1.00
R6222:Igsf10	UTSW	3	59,318,915 (GRCm38)	missense	possibly damaging	0.90
R6224:Igsf10	UTSW	3	59,325,510 (GRCm38)	missense	probably damaging	1.00
R6264:Igsf10	UTSW	3	59,328,507 (GRCm38)	missense	possibly damaging	0.88
R6283:Igsf10	UTSW	3	59,319,449 (GRCm38)	missense	probably damaging	1.00
R6336:Igsf10	UTSW	3	59,330,339 (GRCm38)	missense	probably benign	0.00
R6490:Igsf10	UTSW	3	59,329,571 (GRCm38)	missense	probably benign	0.06
R6785:Igsf10	UTSW	3	59,319,244 (GRCm38)	missense	probably damaging	1.00
R6873:Igsf10	UTSW	3	59,328,444 (GRCm38)	missense	probably benign
R6889:Igsf10	UTSW	3	59,331,933 (GRCm38)	missense	probably benign
R7024:Igsf10	UTSW	3	59,331,701 (GRCm38)	missense	probably benign	0.00
R7056:Igsf10	UTSW	3	59,331,080 (GRCm38)	missense	probably damaging	1.00
R7128:Igsf10	UTSW	3	59,328,905 (GRCm38)	missense	probably benign
R7251:Igsf10	UTSW	3	59,319,454 (GRCm38)	missense	probably damaging	1.00
R7313:Igsf10	UTSW	3	59,329,416 (GRCm38)	missense	probably benign	0.05
R7340:Igsf10	UTSW	3	59,325,768 (GRCm38)	missense	probably damaging	1.00
R7447:Igsf10	UTSW	3	59,331,801 (GRCm38)	missense	probably benign	0.39
R7506:Igsf10	UTSW	3	59,319,354 (GRCm38)	missense	probably damaging	1.00
R7678:Igsf10	UTSW	3	59,319,340 (GRCm38)	missense	possibly damaging	0.81
R7695:Igsf10	UTSW	3	59,326,191 (GRCm38)	missense	probably damaging	1.00
R7709:Igsf10	UTSW	3	59,331,543 (GRCm38)	missense	probably damaging	0.96
R7749:Igsf10	UTSW	3	59,329,128 (GRCm38)	missense	possibly damaging	0.88
R7808:Igsf10	UTSW	3	59,328,068 (GRCm38)	missense	probably benign	0.00
R7850:Igsf10	UTSW	3	59,319,632 (GRCm38)	missense	probably benign	0.33
R7879:Igsf10	UTSW	3	59,330,724 (GRCm38)	missense	probably damaging	1.00
R7886:Igsf10	UTSW	3	59,328,327 (GRCm38)	missense	probably benign	0.01
R7891:Igsf10	UTSW	3	59,328,411 (GRCm38)	nonsense	probably null
R7946:Igsf10	UTSW	3	59,319,704 (GRCm38)	missense	possibly damaging	0.69
R7948:Igsf10	UTSW	3	59,331,858 (GRCm38)	missense	probably benign	0.02
R8004:Igsf10	UTSW	3	59,329,709 (GRCm38)	missense	probably benign	0.01
R8096:Igsf10	UTSW	3	59,328,959 (GRCm38)	missense	probably damaging	0.98
R8141:Igsf10	UTSW	3	59,330,528 (GRCm38)	missense	probably damaging	0.96
R8183:Igsf10	UTSW	3	59,330,615 (GRCm38)	missense	probably benign	0.04
R8203:Igsf10	UTSW	3	59,328,833 (GRCm38)	missense	probably benign	0.11
R8325:Igsf10	UTSW	3	59,318,533 (GRCm38)	missense	probably damaging	0.96
R8350:Igsf10	UTSW	3	59,331,528 (GRCm38)	missense	probably damaging	1.00
R8387:Igsf10	UTSW	3	59,329,143 (GRCm38)	missense	probably damaging	1.00
R8488:Igsf10	UTSW	3	59,320,010 (GRCm38)	missense	probably damaging	1.00
R8697:Igsf10	UTSW	3	59,318,887 (GRCm38)	missense	probably benign	0.02
R8786:Igsf10	UTSW	3	59,330,642 (GRCm38)	missense	probably benign	0.25
R8804:Igsf10	UTSW	3	59,336,455 (GRCm38)	missense	probably damaging	1.00
R8886:Igsf10	UTSW	3	59,329,989 (GRCm38)	missense	probably benign	0.00
R8902:Igsf10	UTSW	3	59,336,212 (GRCm38)	missense	probably benign	0.00
R8906:Igsf10	UTSW	3	59,326,318 (GRCm38)	missense	probably benign	0.01
R8917:Igsf10	UTSW	3	59,319,467 (GRCm38)	missense	possibly damaging	0.69
R9051:Igsf10	UTSW	3	59,329,247 (GRCm38)	missense	probably benign	0.00
R9178:Igsf10	UTSW	3	59,326,059 (GRCm38)	missense	possibly damaging	0.69
R9228:Igsf10	UTSW	3	59,336,422 (GRCm38)	missense	probably damaging	1.00
R9230:Igsf10	UTSW	3	59,336,422 (GRCm38)	missense	probably damaging	1.00
R9231:Igsf10	UTSW	3	59,336,422 (GRCm38)	missense	probably damaging	1.00
R9232:Igsf10	UTSW	3	59,336,422 (GRCm38)	missense	probably damaging	1.00
R9417:Igsf10	UTSW	3	59,329,105 (GRCm38)	missense	possibly damaging	0.94
R9609:Igsf10	UTSW	3	59,319,448 (GRCm38)	missense	probably damaging	1.00
R9631:Igsf10	UTSW	3	59,330,483 (GRCm38)	missense	probably damaging	1.00
R9689:Igsf10	UTSW	3	59,326,203 (GRCm38)	missense	probably damaging	1.00
R9762:Igsf10	UTSW	3	59,329,685 (GRCm38)	missense	probably damaging	1.00
R9770:Igsf10	UTSW	3	59,319,778 (GRCm38)	missense	probably benign	0.07
R9798:Igsf10	UTSW	3	59,331,705 (GRCm38)	missense	probably damaging	1.00
Z1088:Igsf10	UTSW	3	59,329,938 (GRCm38)	missense	possibly damaging	0.59
Z1177:Igsf10	UTSW	3	59,329,605 (GRCm38)	nonsense	probably null

Predicted Primers

PCR Primer
(F):5'- CAGTTCTGTTGAGCTGCAGG -3'
(R):5'- AGGACAATGGATCTGCCTCC -3'

Sequencing Primer
(F):5'- GTTGGAACCAAAAAGGATCTGCTTTG -3'
(R):5'- AGATTTCATAGAACCTTTTGGCTCC -3'

Posted On

2017-10-10