Incidental Mutation 'R0532:Med13l'
| ID |
49232 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Med13l
|
| Ensembl Gene |
ENSMUSG00000018076 |
| Gene Name |
mediator complex subunit 13-like |
| Synonyms |
9030618F05Rik, Trap240L, 6330591G05Rik, Thrap2, 2210413I17Rik |
| MMRRC Submission |
038724-MU
|
| Accession Numbers |
|
| Essential gene? |
Probably essential
(E-score: 0.968)
|
| Stock # |
R0532 (G1)
|
| Quality Score |
225 |
|
Status
|
Validated
|
| Chromosome |
5 |
| Chromosomal Location |
118698744-118903503 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
T to A
at 118897188 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Serine to Threonine
at position 2089
(S2089T)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000144092
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000100816]
[ENSMUST00000201010]
|
| AlphaFold |
no structure available at present |
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000100816
AA Change: S2080T
PolyPhen 2
Score 0.778 (Sensitivity: 0.85; Specificity: 0.93)
|
| SMART Domains |
Protein: ENSMUSP00000098379
Gene: ENSMUSG00000018076
AA Change: S2080T
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:Med13_N
|
1 |
380 |
2.5e-116 |
PFAM |
|
low complexity region
|
442 |
460 |
N/A |
INTRINSIC |
|
low complexity region
|
542 |
558 |
N/A |
INTRINSIC |
|
low complexity region
|
1020 |
1031 |
N/A |
INTRINSIC |
|
low complexity region
|
1044 |
1060 |
N/A |
INTRINSIC |
|
low complexity region
|
1541 |
1593 |
N/A |
INTRINSIC |
|
low complexity region
|
1601 |
1611 |
N/A |
INTRINSIC |
|
Pfam:Med13_C
|
1675 |
2197 |
1e-142 |
PFAM |
|
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000201010
AA Change: S2089T
PolyPhen 2
Score 0.778 (Sensitivity: 0.85; Specificity: 0.93)
|
| SMART Domains |
Protein: ENSMUSP00000144092
Gene: ENSMUSG00000018076
AA Change: S2089T
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:Med13_N
|
1 |
380 |
1e-112 |
PFAM |
|
low complexity region
|
442 |
460 |
N/A |
INTRINSIC |
|
low complexity region
|
542 |
558 |
N/A |
INTRINSIC |
|
low complexity region
|
1020 |
1031 |
N/A |
INTRINSIC |
|
low complexity region
|
1044 |
1060 |
N/A |
INTRINSIC |
|
low complexity region
|
1541 |
1593 |
N/A |
INTRINSIC |
|
low complexity region
|
1601 |
1611 |
N/A |
INTRINSIC |
|
Pfam:Med13_C
|
1675 |
2206 |
1.7e-138 |
PFAM |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000202538
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000202787
|
| Meta Mutation Damage Score |
0.0887 |
| Coding Region Coverage |
- 1x: 99.2%
- 3x: 98.4%
- 10x: 96.5%
- 20x: 93.2%
|
| Validation Efficiency |
100% (90/90) |
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] The protein encoded by this gene is a subunit of the Mediator complex, a large complex of proteins that functions as a transcriptional coactivator for most RNA polymerase II-transcribed genes. The encoded protein is involved in early development of the heart and brain. Defects in this gene are a cause of transposition of the great arteries, dextro-looped (DTGA).[provided by RefSeq, Jul 2010]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 91 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 4921524L21Rik |
A |
T |
18: 6,638,618 (GRCm39) |
E339V |
possibly damaging |
Het |
| 9230009I02Rik |
A |
T |
11: 50,982,405 (GRCm39) |
|
noncoding transcript |
Het |
| 9230112D13Rik |
A |
T |
14: 34,234,054 (GRCm39) |
I79K |
unknown |
Het |
| Adam25 |
C |
T |
8: 41,208,987 (GRCm39) |
T751I |
probably benign |
Het |
| Adgrv1 |
C |
A |
13: 81,727,015 (GRCm39) |
V446L |
probably damaging |
Het |
| Afap1 |
C |
A |
5: 36,125,944 (GRCm39) |
A313D |
possibly damaging |
Het |
| Akap6 |
A |
G |
12: 52,934,766 (GRCm39) |
T753A |
probably benign |
Het |
| Aldh16a1 |
G |
T |
7: 44,792,262 (GRCm39) |
T730N |
probably damaging |
Het |
| Amfr |
A |
T |
8: 94,725,736 (GRCm39) |
M215K |
probably damaging |
Het |
| Apob |
A |
G |
12: 8,066,188 (GRCm39) |
R4386G |
possibly damaging |
Het |
| Arhgap45 |
A |
T |
10: 79,857,917 (GRCm39) |
M217L |
possibly damaging |
Het |
| Baiap2l2 |
C |
T |
15: 79,168,276 (GRCm39) |
E49K |
possibly damaging |
Het |
| Baz1a |
C |
T |
12: 54,981,605 (GRCm39) |
E350K |
possibly damaging |
Het |
| Bbx |
A |
T |
16: 50,086,647 (GRCm39) |
V83D |
probably damaging |
Het |
| Btaf1 |
T |
C |
19: 36,928,586 (GRCm39) |
|
probably benign |
Het |
| Cacna2d1 |
G |
A |
5: 16,567,271 (GRCm39) |
E942K |
probably benign |
Het |
| Cad |
T |
C |
5: 31,219,531 (GRCm39) |
|
probably benign |
Het |
| Ccdc96 |
A |
G |
5: 36,643,710 (GRCm39) |
K572R |
probably benign |
Het |
| Cdc5l |
G |
A |
17: 45,726,610 (GRCm39) |
R321W |
probably damaging |
Het |
| Cep164 |
G |
A |
9: 45,721,124 (GRCm39) |
R93* |
probably null |
Het |
| Cir1 |
A |
G |
2: 73,140,799 (GRCm39) |
|
probably null |
Het |
| Crocc |
A |
G |
4: 140,757,558 (GRCm39) |
S912P |
possibly damaging |
Het |
| Cwf19l2 |
T |
C |
9: 3,431,057 (GRCm39) |
L463P |
probably benign |
Het |
| Cyp3a59 |
C |
T |
5: 146,033,463 (GRCm39) |
Q200* |
probably null |
Het |
| Cyp4b1 |
G |
T |
4: 115,484,073 (GRCm39) |
P303T |
probably damaging |
Het |
| Dcbld1 |
C |
A |
10: 52,193,173 (GRCm39) |
T306K |
probably benign |
Het |
| Dgat2 |
A |
G |
7: 98,818,988 (GRCm39) |
V56A |
possibly damaging |
Het |
| Dnajc16 |
A |
C |
4: 141,516,320 (GRCm39) |
L16R |
probably damaging |
Het |
| Dnmt1 |
A |
C |
9: 20,829,852 (GRCm39) |
|
probably benign |
Het |
| Dus3l |
A |
G |
17: 57,076,308 (GRCm39) |
I528V |
probably damaging |
Het |
| Egflam |
T |
C |
15: 7,263,718 (GRCm39) |
D744G |
probably benign |
Het |
| Epb41 |
A |
C |
4: 131,706,106 (GRCm39) |
|
probably benign |
Het |
| Eri2 |
C |
T |
7: 119,385,206 (GRCm39) |
V432I |
probably benign |
Het |
| Esyt2 |
A |
G |
12: 116,320,818 (GRCm39) |
|
probably benign |
Het |
| Extl3 |
A |
T |
14: 65,315,122 (GRCm39) |
M20K |
probably benign |
Het |
| Fam32a |
A |
G |
8: 72,976,063 (GRCm39) |
Y103C |
probably damaging |
Het |
| Fat4 |
T |
C |
3: 39,035,870 (GRCm39) |
V3174A |
probably benign |
Het |
| Fbxo40 |
T |
A |
16: 36,789,984 (GRCm39) |
E375D |
possibly damaging |
Het |
| Frrs1 |
A |
G |
3: 116,676,813 (GRCm39) |
T182A |
probably benign |
Het |
| Fry |
A |
G |
5: 150,357,172 (GRCm39) |
|
probably benign |
Het |
| Fry |
T |
C |
5: 150,402,226 (GRCm39) |
|
probably benign |
Het |
| Fsip2 |
A |
G |
2: 82,808,129 (GRCm39) |
I1483V |
probably benign |
Het |
| Glra3 |
T |
A |
8: 56,578,111 (GRCm39) |
D389E |
probably benign |
Het |
| Gpr3 |
A |
T |
4: 132,937,796 (GRCm39) |
I292N |
probably damaging |
Het |
| Grina |
T |
C |
15: 76,133,045 (GRCm39) |
M230T |
probably damaging |
Het |
| Igkv11-125 |
G |
A |
6: 67,890,603 (GRCm39) |
W16* |
probably null |
Het |
| Il18r1 |
T |
C |
1: 40,514,061 (GRCm39) |
V89A |
probably damaging |
Het |
| Ino80 |
T |
C |
2: 119,212,464 (GRCm39) |
E1286G |
possibly damaging |
Het |
| Iqch |
G |
A |
9: 63,415,514 (GRCm39) |
|
probably benign |
Het |
| Itpr2 |
G |
T |
6: 146,013,898 (GRCm39) |
Q2666K |
probably damaging |
Het |
| Kcnh3 |
A |
G |
15: 99,130,844 (GRCm39) |
D487G |
probably damaging |
Het |
| Kdm1a |
A |
G |
4: 136,288,377 (GRCm39) |
L402P |
probably damaging |
Het |
| Klhl10 |
T |
G |
11: 100,337,937 (GRCm39) |
|
probably benign |
Het |
| Krt39 |
T |
C |
11: 99,405,617 (GRCm39) |
T428A |
possibly damaging |
Het |
| Mapk3 |
G |
A |
7: 126,362,558 (GRCm39) |
|
probably benign |
Het |
| Mex3c |
G |
A |
18: 73,723,124 (GRCm39) |
D406N |
possibly damaging |
Het |
| Mki67 |
G |
A |
7: 135,299,893 (GRCm39) |
R1714* |
probably null |
Het |
| Mmp9 |
C |
A |
2: 164,791,740 (GRCm39) |
S211* |
probably null |
Het |
| Nat8f2 |
G |
T |
6: 85,844,784 (GRCm39) |
Q193K |
probably benign |
Het |
| Omt2a |
C |
A |
9: 78,220,187 (GRCm39) |
A71S |
possibly damaging |
Het |
| Or10ak11 |
T |
G |
4: 118,686,897 (GRCm39) |
T247P |
probably damaging |
Het |
| Or5ac22 |
T |
C |
16: 59,134,964 (GRCm39) |
K269E |
probably benign |
Het |
| Pdgfra |
G |
A |
5: 75,331,434 (GRCm39) |
V315I |
probably benign |
Het |
| Pdgfrb |
A |
G |
18: 61,216,337 (GRCm39) |
D1065G |
probably damaging |
Het |
| Pfas |
A |
T |
11: 68,893,455 (GRCm39) |
|
probably benign |
Het |
| Pramel5 |
T |
C |
4: 143,999,310 (GRCm39) |
E259G |
probably benign |
Het |
| Prpf6 |
A |
G |
2: 181,264,004 (GRCm39) |
Y222C |
possibly damaging |
Het |
| Rbck1 |
C |
A |
2: 152,166,250 (GRCm39) |
Q229H |
probably damaging |
Het |
| Rdm1 |
T |
A |
11: 101,526,661 (GRCm39) |
C278S |
probably benign |
Het |
| Sall1 |
T |
C |
8: 89,759,819 (GRCm39) |
D95G |
probably benign |
Het |
| Scn1a |
T |
A |
2: 66,148,167 (GRCm39) |
D1126V |
probably damaging |
Het |
| Scn4a |
C |
T |
11: 106,221,226 (GRCm39) |
G811D |
probably benign |
Het |
| Sh2b1 |
A |
G |
7: 126,071,444 (GRCm39) |
I247T |
probably benign |
Het |
| Shprh |
C |
A |
10: 11,038,556 (GRCm39) |
T437K |
possibly damaging |
Het |
| Slc13a4 |
A |
T |
6: 35,264,339 (GRCm39) |
|
probably null |
Het |
| Slc16a1 |
C |
A |
3: 104,560,734 (GRCm39) |
Y346* |
probably null |
Het |
| Slc25a38 |
G |
T |
9: 119,949,772 (GRCm39) |
A163S |
probably damaging |
Het |
| Slc6a12 |
G |
A |
6: 121,333,877 (GRCm39) |
V238I |
probably damaging |
Het |
| Slc8b1 |
C |
A |
5: 120,657,736 (GRCm39) |
D66E |
probably damaging |
Het |
| Snapin |
A |
G |
3: 90,396,893 (GRCm39) |
L106P |
probably damaging |
Het |
| Tas2r122 |
G |
A |
6: 132,688,791 (GRCm39) |
S34F |
possibly damaging |
Het |
| Tiam2 |
A |
G |
17: 3,471,921 (GRCm39) |
K521R |
probably damaging |
Het |
| Tmem81 |
C |
G |
1: 132,435,567 (GRCm39) |
I124M |
probably damaging |
Het |
| Ttc3 |
T |
C |
16: 94,188,189 (GRCm39) |
|
probably benign |
Het |
| Uba1y |
T |
C |
Y: 820,911 (GRCm39) |
F31L |
probably benign |
Het |
| Ucp3 |
A |
G |
7: 100,131,186 (GRCm39) |
|
probably benign |
Het |
| Vcan |
T |
C |
13: 89,851,891 (GRCm39) |
E1023G |
probably damaging |
Het |
| Vmn2r45 |
A |
G |
7: 8,474,820 (GRCm39) |
I736T |
probably damaging |
Het |
| Vps36 |
T |
C |
8: 22,708,261 (GRCm39) |
F342L |
probably benign |
Het |
| Zc3hc1 |
A |
G |
6: 30,374,929 (GRCm39) |
|
probably benign |
Het |
| Zmym4 |
G |
A |
4: 126,792,194 (GRCm39) |
Q596* |
probably null |
Het |
|
| Other mutations in Med13l |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00232:Med13l
|
APN |
5 |
118,862,136 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL01012:Med13l
|
APN |
5 |
118,872,093 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL01316:Med13l
|
APN |
5 |
118,900,846 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01529:Med13l
|
APN |
5 |
118,880,400 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01731:Med13l
|
APN |
5 |
118,880,472 (GRCm39) |
missense |
probably benign |
0.05 |
|
IGL01790:Med13l
|
APN |
5 |
118,731,587 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02394:Med13l
|
APN |
5 |
118,886,898 (GRCm39) |
missense |
probably benign |
0.37 |
|
IGL02432:Med13l
|
APN |
5 |
118,876,465 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
IGL02698:Med13l
|
APN |
5 |
118,900,894 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL02801:Med13l
|
APN |
5 |
118,883,178 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03242:Med13l
|
APN |
5 |
118,885,510 (GRCm39) |
missense |
probably benign |
|
|
IGL03270:Med13l
|
APN |
5 |
118,869,495 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Basics
|
UTSW |
5 |
118,897,329 (GRCm39) |
critical splice donor site |
probably null |
|
|
firmament
|
UTSW |
5 |
118,883,071 (GRCm39) |
splice site |
probably null |
|
|
Fundament
|
UTSW |
5 |
118,859,539 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Root
|
UTSW |
5 |
118,731,510 (GRCm39) |
missense |
probably damaging |
1.00 |
|
P0035:Med13l
|
UTSW |
5 |
118,880,685 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0051:Med13l
|
UTSW |
5 |
118,880,720 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0051:Med13l
|
UTSW |
5 |
118,880,720 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0136:Med13l
|
UTSW |
5 |
118,862,115 (GRCm39) |
missense |
probably benign |
0.15 |
|
R0158:Med13l
|
UTSW |
5 |
118,880,514 (GRCm39) |
missense |
unknown |
|
|
R0197:Med13l
|
UTSW |
5 |
118,809,067 (GRCm39) |
splice site |
probably benign |
|
|
R0370:Med13l
|
UTSW |
5 |
118,879,891 (GRCm39) |
missense |
probably benign |
0.14 |
|
R0492:Med13l
|
UTSW |
5 |
118,876,560 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0726:Med13l
|
UTSW |
5 |
118,886,749 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R0738:Med13l
|
UTSW |
5 |
118,889,698 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R0827:Med13l
|
UTSW |
5 |
118,864,312 (GRCm39) |
splice site |
probably benign |
|
|
R0883:Med13l
|
UTSW |
5 |
118,809,067 (GRCm39) |
splice site |
probably benign |
|
|
R0959:Med13l
|
UTSW |
5 |
118,892,350 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R1458:Med13l
|
UTSW |
5 |
118,876,524 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1562:Med13l
|
UTSW |
5 |
118,876,584 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1577:Med13l
|
UTSW |
5 |
118,859,457 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1661:Med13l
|
UTSW |
5 |
118,887,813 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1665:Med13l
|
UTSW |
5 |
118,887,813 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1720:Med13l
|
UTSW |
5 |
118,880,060 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1929:Med13l
|
UTSW |
5 |
118,866,898 (GRCm39) |
missense |
probably benign |
0.01 |
|
R1967:Med13l
|
UTSW |
5 |
118,899,387 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R2301:Med13l
|
UTSW |
5 |
118,731,512 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3691:Med13l
|
UTSW |
5 |
118,859,562 (GRCm39) |
missense |
probably benign |
0.16 |
|
R3895:Med13l
|
UTSW |
5 |
118,899,388 (GRCm39) |
missense |
probably null |
0.99 |
|
R4043:Med13l
|
UTSW |
5 |
118,731,528 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4593:Med13l
|
UTSW |
5 |
118,880,625 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4902:Med13l
|
UTSW |
5 |
118,883,195 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4995:Med13l
|
UTSW |
5 |
118,869,014 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
R5010:Med13l
|
UTSW |
5 |
118,731,615 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R5057:Med13l
|
UTSW |
5 |
118,856,558 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5369:Med13l
|
UTSW |
5 |
118,862,075 (GRCm39) |
missense |
probably benign |
0.02 |
|
R5446:Med13l
|
UTSW |
5 |
118,880,462 (GRCm39) |
missense |
possibly damaging |
0.81 |
|
R5564:Med13l
|
UTSW |
5 |
118,880,105 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5566:Med13l
|
UTSW |
5 |
118,866,730 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R5580:Med13l
|
UTSW |
5 |
118,889,695 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R5634:Med13l
|
UTSW |
5 |
118,698,915 (GRCm39) |
missense |
possibly damaging |
0.88 |
|
R5748:Med13l
|
UTSW |
5 |
118,731,510 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5764:Med13l
|
UTSW |
5 |
118,866,707 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5765:Med13l
|
UTSW |
5 |
118,866,707 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R6083:Med13l
|
UTSW |
5 |
118,859,551 (GRCm39) |
missense |
possibly damaging |
0.80 |
|
R6504:Med13l
|
UTSW |
5 |
118,892,386 (GRCm39) |
missense |
probably benign |
0.34 |
|
R6546:Med13l
|
UTSW |
5 |
118,859,539 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6797:Med13l
|
UTSW |
5 |
118,897,329 (GRCm39) |
critical splice donor site |
probably null |
|
|
R6911:Med13l
|
UTSW |
5 |
118,893,723 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R6942:Med13l
|
UTSW |
5 |
118,883,071 (GRCm39) |
splice site |
probably null |
|
|
R7018:Med13l
|
UTSW |
5 |
118,890,051 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7096:Med13l
|
UTSW |
5 |
118,859,991 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
R7113:Med13l
|
UTSW |
5 |
118,864,330 (GRCm39) |
missense |
probably benign |
0.09 |
|
R7136:Med13l
|
UTSW |
5 |
118,859,587 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
R7140:Med13l
|
UTSW |
5 |
118,880,037 (GRCm39) |
missense |
probably benign |
0.27 |
|
R7345:Med13l
|
UTSW |
5 |
118,880,825 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7409:Med13l
|
UTSW |
5 |
118,892,386 (GRCm39) |
missense |
probably benign |
0.34 |
|
R7410:Med13l
|
UTSW |
5 |
118,698,897 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R7432:Med13l
|
UTSW |
5 |
118,890,003 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7486:Med13l
|
UTSW |
5 |
118,866,539 (GRCm39) |
missense |
probably benign |
0.17 |
|
R7509:Med13l
|
UTSW |
5 |
118,886,995 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R7722:Med13l
|
UTSW |
5 |
118,885,472 (GRCm39) |
missense |
probably benign |
0.32 |
|
R7802:Med13l
|
UTSW |
5 |
118,866,655 (GRCm39) |
missense |
probably benign |
0.03 |
|
R8081:Med13l
|
UTSW |
5 |
118,866,333 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8260:Med13l
|
UTSW |
5 |
118,886,794 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R8266:Med13l
|
UTSW |
5 |
118,880,174 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8347:Med13l
|
UTSW |
5 |
118,880,662 (GRCm39) |
missense |
probably benign |
|
|
R8365:Med13l
|
UTSW |
5 |
118,866,709 (GRCm39) |
missense |
possibly damaging |
0.81 |
|
R8508:Med13l
|
UTSW |
5 |
118,892,386 (GRCm39) |
missense |
probably benign |
0.34 |
|
R8920:Med13l
|
UTSW |
5 |
118,885,543 (GRCm39) |
nonsense |
probably null |
|
|
R8970:Med13l
|
UTSW |
5 |
118,883,164 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8994:Med13l
|
UTSW |
5 |
118,866,226 (GRCm39) |
missense |
possibly damaging |
0.78 |
|
R9045:Med13l
|
UTSW |
5 |
118,880,816 (GRCm39) |
missense |
probably benign |
|
|
R9401:Med13l
|
UTSW |
5 |
118,883,089 (GRCm39) |
missense |
probably benign |
0.14 |
|
R9445:Med13l
|
UTSW |
5 |
118,862,214 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9446:Med13l
|
UTSW |
5 |
118,876,567 (GRCm39) |
missense |
probably benign |
0.11 |
|
R9714:Med13l
|
UTSW |
5 |
118,866,438 (GRCm39) |
missense |
probably benign |
0.44 |
|
R9777:Med13l
|
UTSW |
5 |
118,887,024 (GRCm39) |
missense |
probably benign |
|
|
R9781:Med13l
|
UTSW |
5 |
118,868,032 (GRCm39) |
missense |
possibly damaging |
0.60 |
|
R9797:Med13l
|
UTSW |
5 |
118,880,144 (GRCm39) |
missense |
probably damaging |
1.00 |
|
X0065:Med13l
|
UTSW |
5 |
118,867,948 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Z1088:Med13l
|
UTSW |
5 |
118,887,706 (GRCm39) |
missense |
probably damaging |
0.98 |
|
| Predicted Primers |
PCR Primer
(F):5'- ATGCAGTGACACACAGCTCCAG -3'
(R):5'- AGCGTGCATCTACCAACCTTCAG -3'
Sequencing Primer
(F):5'- CAAAACCTTTGTCTGGTCGATAGTG -3'
(R):5'- TCTACCAACCTTCAGGAAGAGTG -3'
|
| Posted On |
2013-06-12 |
Incidental Mutation