Incidental Mutation 'R4666:Lrrc7'
| ID |
500750 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Lrrc7
|
| Ensembl Gene |
ENSMUSG00000028176 |
| Gene Name |
leucine rich repeat containing 7 |
| Synonyms |
densin |
| MMRRC Submission |
041924-MU
|
| Accession Numbers |
Genbank: NM_001081358; MGI: 2676665 |
| Essential gene? |
Possibly essential
(E-score: 0.691)
|
| Stock # |
R4666 (G1)
|
| Quality Score |
184 |
|
Status
|
Not validated
|
| Chromosome |
3 |
| Chromosomal Location |
158082891-158562221 bp(-) (GRCm38) |
| Type of Mutation |
critical splice donor site |
| DNA Base Change (assembly) |
GAAGTTGTTTGGAGATTCTTATCTTA to GA
at 158318408 bp (GRCm38)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000106044]
[ENSMUST00000199890]
[ENSMUST00000200137]
|
| AlphaFold |
no structure available at present |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000106044
|
| SMART Domains |
Protein: ENSMUSP00000101659
Gene: ENSMUSG00000028176
| Domain | Start | End | E-Value | Type |
|---|
|
LRR
|
53 |
73 |
3.65e0 |
SMART |
|
LRR
|
96 |
118 |
2.2e1 |
SMART |
|
LRR
|
142 |
164 |
4.21e1 |
SMART |
|
LRR
|
165 |
187 |
7.36e0 |
SMART |
|
LRR
|
188 |
210 |
7.05e-1 |
SMART |
|
LRR
|
211 |
233 |
3.09e1 |
SMART |
|
LRR
|
234 |
257 |
4.21e1 |
SMART |
|
LRR
|
258 |
279 |
2.61e2 |
SMART |
|
LRR
|
280 |
303 |
3.52e-1 |
SMART |
|
LRR
|
326 |
349 |
1.99e0 |
SMART |
|
LRR
|
372 |
394 |
2.63e0 |
SMART |
|
low complexity region
|
466 |
476 |
N/A |
INTRINSIC |
|
low complexity region
|
692 |
705 |
N/A |
INTRINSIC |
|
Blast:PDZ
|
708 |
736 |
1e-5 |
BLAST |
|
low complexity region
|
787 |
797 |
N/A |
INTRINSIC |
|
low complexity region
|
864 |
878 |
N/A |
INTRINSIC |
|
Blast:PDZ
|
1349 |
1378 |
2e-11 |
BLAST |
|
PDZ
|
1460 |
1540 |
1.33e-19 |
SMART |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000199890
|
| SMART Domains |
Protein: ENSMUSP00000142440
Gene: ENSMUSG00000028176
| Domain | Start | End | E-Value | Type |
|---|
|
LRR
|
53 |
73 |
3.65e0 |
SMART |
|
LRR
|
96 |
118 |
2.2e1 |
SMART |
|
LRR
|
142 |
164 |
4.21e1 |
SMART |
|
LRR
|
165 |
187 |
7.36e0 |
SMART |
|
LRR
|
188 |
210 |
7.05e-1 |
SMART |
|
LRR
|
211 |
233 |
3.09e1 |
SMART |
|
LRR
|
234 |
257 |
4.21e1 |
SMART |
|
LRR
|
258 |
279 |
2.61e2 |
SMART |
|
LRR
|
280 |
303 |
3.52e-1 |
SMART |
|
LRR
|
326 |
349 |
1.99e0 |
SMART |
|
LRR
|
372 |
394 |
2.63e0 |
SMART |
|
low complexity region
|
466 |
476 |
N/A |
INTRINSIC |
|
low complexity region
|
692 |
705 |
N/A |
INTRINSIC |
|
Blast:PDZ
|
708 |
736 |
9e-6 |
BLAST |
|
low complexity region
|
787 |
797 |
N/A |
INTRINSIC |
|
low complexity region
|
864 |
878 |
N/A |
INTRINSIC |
|
Blast:PDZ
|
1328 |
1364 |
1e-15 |
BLAST |
|
low complexity region
|
1374 |
1387 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000200137
|
| SMART Domains |
Protein: ENSMUSP00000142498
Gene: ENSMUSG00000028176
| Domain | Start | End | E-Value | Type |
|---|
|
LRR
|
52 |
69 |
7.6e-1 |
SMART |
|
LRR
|
73 |
92 |
4.2e-1 |
SMART |
|
LRR
|
96 |
115 |
3.4e-1 |
SMART |
|
LRR
|
142 |
164 |
1.8e-1 |
SMART |
|
LRR
|
165 |
184 |
1.5e-1 |
SMART |
|
LRR
|
188 |
207 |
2e-2 |
SMART |
|
LRR
|
211 |
233 |
1.3e-1 |
SMART |
|
LRR
|
234 |
257 |
1.7e-1 |
SMART |
|
LRR
|
257 |
276 |
1e0 |
SMART |
|
LRR
|
280 |
299 |
3.1e-2 |
SMART |
|
LRR
|
303 |
322 |
6.6e-1 |
SMART |
|
LRR
|
326 |
345 |
2.1e-1 |
SMART |
|
LRR
|
372 |
391 |
1.2e-1 |
SMART |
|
low complexity region
|
466 |
476 |
N/A |
INTRINSIC |
|
low complexity region
|
692 |
705 |
N/A |
INTRINSIC |
|
Blast:PDZ
|
708 |
736 |
1e-5 |
BLAST |
|
low complexity region
|
787 |
797 |
N/A |
INTRINSIC |
|
low complexity region
|
864 |
878 |
N/A |
INTRINSIC |
|
Blast:PDZ
|
1302 |
1331 |
2e-11 |
BLAST |
|
PDZ
|
1413 |
1493 |
6.4e-22 |
SMART |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000200196
|
| Meta Mutation Damage Score |
0.0898 |
| Coding Region Coverage |
- 1x: 99.3%
- 3x: 98.7%
- 10x: 97.5%
- 20x: 95.8%
|
| Validation Efficiency |
|
| MGI Phenotype |
PHENOTYPE: Mice homozygous for a knock-out allele exhibit limb grasping, reduced long term depression, increased anxiety, increased aggression towards other mice, impaired spatial memory, decreased prepulse inhibition, decreased nesting building behavior, and abnormal dendritic spines. [provided by MGI curators]
|
| Allele List at MGI |
All alleles(2) : Gene trapped(2) |
| Other mutations in this stock |
Total: 100 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 2410137M14Rik |
G |
A |
17: 36,978,902 |
S12L |
probably benign |
Het |
| 4921507P07Rik |
G |
T |
6: 50,595,828 |
T35K |
possibly damaging |
Het |
| 4931406P16Rik |
T |
C |
7: 34,284,773 |
M142V |
probably damaging |
Het |
| Abce1 |
A |
G |
8: 79,687,486 |
V532A |
probably damaging |
Het |
| Adamts12 |
T |
A |
15: 11,311,492 |
N1278K |
probably benign |
Het |
| Adipor1 |
T |
A |
1: 134,424,905 |
I138N |
probably damaging |
Het |
| Aox2 |
C |
T |
1: 58,304,597 |
Q480* |
probably null |
Het |
| Arhgef38 |
C |
T |
3: 133,140,772 |
|
probably null |
Het |
| Atmin |
A |
G |
8: 116,957,959 |
D786G |
probably damaging |
Het |
| Capn1 |
A |
T |
19: 6,011,015 |
N253K |
probably benign |
Het |
| Cdh8 |
T |
C |
8: 99,024,902 |
T728A |
possibly damaging |
Het |
| Celsr1 |
A |
G |
15: 86,030,494 |
S1093P |
probably damaging |
Het |
| Cep135 |
C |
A |
5: 76,616,854 |
P560T |
probably benign |
Het |
| Chfr |
C |
T |
5: 110,144,867 |
Q167* |
probably null |
Het |
| Chrna4 |
A |
G |
2: 181,037,493 |
S54P |
probably damaging |
Het |
| Cntln |
A |
G |
4: 84,971,216 |
N312S |
probably benign |
Het |
| Cntn6 |
A |
G |
6: 104,728,284 |
E154G |
probably benign |
Het |
| Col6a6 |
T |
A |
9: 105,767,342 |
Y1249F |
possibly damaging |
Het |
| Cpsf2 |
T |
C |
12: 101,983,207 |
S61P |
probably damaging |
Het |
| Cpvl |
C |
T |
6: 53,931,933 |
E282K |
probably benign |
Het |
| Cryba2 |
C |
T |
1: 74,890,048 |
D179N |
probably benign |
Het |
| Daglb |
A |
T |
5: 143,503,349 |
R654W |
probably damaging |
Het |
| Dennd3 |
A |
G |
15: 73,570,860 |
D1244G |
probably damaging |
Het |
| Dhx57 |
T |
C |
17: 80,274,961 |
E405G |
probably damaging |
Het |
| Dnah10 |
T |
C |
5: 124,828,472 |
M4060T |
possibly damaging |
Het |
| Dph1 |
A |
G |
11: 75,181,330 |
S238P |
probably damaging |
Het |
| Duox1 |
C |
T |
2: 122,319,475 |
P116S |
probably benign |
Het |
| Ebf1 |
A |
G |
11: 44,991,557 |
N447D |
probably damaging |
Het |
| Epg5 |
A |
G |
18: 78,012,864 |
N1751S |
probably benign |
Het |
| Exoc6 |
A |
G |
19: 37,570,505 |
D75G |
probably damaging |
Het |
| Extl2 |
T |
A |
3: 116,024,207 |
I70N |
probably damaging |
Het |
| Fam129c |
G |
T |
8: 71,603,825 |
E390* |
probably null |
Het |
| Fanca |
T |
C |
8: 123,268,972 |
T1364A |
probably damaging |
Het |
| Fbln7 |
T |
A |
2: 128,894,910 |
|
probably null |
Het |
| Foxa3 |
G |
T |
7: 19,014,372 |
C275* |
probably null |
Het |
| Foxred1 |
C |
T |
9: 35,210,855 |
|
probably benign |
Het |
| Galr2 |
A |
G |
11: 116,283,629 |
T362A |
probably benign |
Het |
| Garem2 |
C |
A |
5: 30,114,667 |
R376S |
probably damaging |
Het |
| Gatc |
T |
A |
5: 115,335,547 |
N111I |
probably benign |
Het |
| Gjb4 |
C |
A |
4: 127,351,778 |
K123N |
probably damaging |
Het |
| Gm14025 |
T |
C |
2: 129,038,230 |
H592R |
probably benign |
Het |
| Gm9894 |
T |
C |
13: 67,765,094 |
|
noncoding transcript |
Het |
| Gtdc1 |
T |
C |
2: 44,591,925 |
N301S |
probably benign |
Het |
| Gtf2ird1 |
T |
A |
5: 134,383,902 |
E55V |
probably damaging |
Het |
| Gtsf1 |
T |
C |
15: 103,421,205 |
I96V |
probably benign |
Het |
| Homer1 |
T |
A |
13: 93,402,159 |
I170N |
probably damaging |
Het |
| Homer3 |
G |
A |
8: 70,290,143 |
|
probably null |
Het |
| Hoxb9 |
A |
G |
11: 96,274,831 |
K242R |
possibly damaging |
Het |
| Ifna14 |
T |
C |
4: 88,571,336 |
R155G |
probably benign |
Het |
| Lsm11 |
A |
G |
11: 45,933,813 |
S296P |
probably damaging |
Het |
| Macrod2 |
T |
C |
2: 142,217,599 |
L265P |
probably damaging |
Het |
| Mcu |
G |
A |
10: 59,456,699 |
L53F |
probably damaging |
Het |
| Mpv17l2 |
A |
G |
8: 70,760,415 |
V104A |
possibly damaging |
Het |
| Myh10 |
G |
A |
11: 68,801,730 |
|
probably null |
Het |
| Nemf |
T |
C |
12: 69,312,280 |
E1031G |
probably damaging |
Het |
| Nhsl1 |
G |
A |
10: 18,531,405 |
S1395N |
probably damaging |
Het |
| Nlrp2 |
T |
A |
7: 5,319,189 |
I82F |
probably benign |
Het |
| Nlrp4e |
T |
A |
7: 23,336,780 |
L686* |
probably null |
Het |
| Nudt12os |
T |
A |
17: 59,024,551 |
|
noncoding transcript |
Het |
| Olfr1122 |
T |
A |
2: 87,387,876 |
I57K |
probably damaging |
Het |
| Olfr16 |
G |
A |
1: 172,957,590 |
S265N |
probably benign |
Het |
| Olfr180 |
T |
C |
16: 58,916,584 |
D19G |
probably benign |
Het |
| Olfr205 |
A |
G |
16: 59,329,210 |
Y100H |
possibly damaging |
Het |
| Olfr93 |
A |
T |
17: 37,151,379 |
S44T |
possibly damaging |
Het |
| Olfr944 |
T |
A |
9: 39,217,846 |
M163K |
probably damaging |
Het |
| Pde7a |
T |
C |
3: 19,260,256 |
T59A |
probably damaging |
Het |
| Pde7b |
A |
C |
10: 20,438,750 |
D203E |
probably damaging |
Het |
| Phkg2 |
T |
A |
7: 127,577,984 |
I94N |
possibly damaging |
Het |
| Pik3r2 |
G |
A |
8: 70,768,859 |
T667I |
possibly damaging |
Het |
| Pitx3 |
T |
A |
19: 46,137,101 |
H68L |
possibly damaging |
Het |
| Prcd |
A |
G |
11: 116,668,164 |
|
probably benign |
Het |
| Prune2 |
C |
T |
19: 17,120,188 |
R1019* |
probably null |
Het |
| Psap |
A |
G |
10: 60,300,545 |
D486G |
probably benign |
Het |
| Purb |
A |
T |
11: 6,475,615 |
V91E |
probably damaging |
Het |
| Recql |
C |
A |
6: 142,376,841 |
V112F |
probably damaging |
Het |
| Rptor |
A |
T |
11: 119,743,882 |
I175F |
probably damaging |
Het |
| Sbf1 |
C |
T |
15: 89,295,246 |
V1385M |
probably damaging |
Het |
| Serpinb13 |
C |
T |
1: 106,982,844 |
S66L |
probably damaging |
Het |
| Slc35f6 |
T |
C |
5: 30,655,613 |
L37P |
probably damaging |
Het |
| Slc6a3 |
T |
A |
13: 73,538,581 |
N22K |
possibly damaging |
Het |
| Sorl1 |
A |
T |
9: 42,004,051 |
M1294K |
probably damaging |
Het |
| Sp6 |
C |
A |
11: 97,021,875 |
A138E |
probably benign |
Het |
| Spag8 |
G |
T |
4: 43,653,408 |
|
probably benign |
Het |
| Spon1 |
T |
A |
7: 114,028,969 |
M320K |
probably benign |
Het |
| Tceanc2 |
A |
T |
4: 107,165,560 |
S77T |
probably damaging |
Het |
| Thsd7a |
T |
A |
6: 12,337,314 |
T1235S |
possibly damaging |
Het |
| Thsd7a |
T |
A |
6: 12,504,013 |
I381F |
possibly damaging |
Het |
| Tmc4 |
T |
C |
7: 3,671,271 |
|
probably null |
Het |
| Tmprss11d |
T |
C |
5: 86,309,401 |
D133G |
probably damaging |
Het |
| Trav13n-3 |
T |
A |
14: 53,337,496 |
V65D |
probably damaging |
Het |
| Trpm1 |
G |
T |
7: 64,203,034 |
L65F |
probably damaging |
Het |
| Tyk2 |
C |
T |
9: 21,114,207 |
A741T |
probably damaging |
Het |
| Ube2v1 |
T |
A |
2: 167,610,377 |
Y102F |
probably damaging |
Het |
| Uckl1 |
A |
T |
2: 181,574,868 |
S95T |
possibly damaging |
Het |
| Uhrf1bp1 |
G |
T |
17: 27,893,503 |
W1222L |
possibly damaging |
Het |
| Vcan |
C |
A |
13: 89,679,934 |
W2171L |
probably damaging |
Het |
| Vmn1r64 |
T |
C |
7: 5,884,358 |
N62S |
probably damaging |
Het |
| Vmn2r67 |
T |
C |
7: 85,150,623 |
D469G |
probably benign |
Het |
| Vps13b |
A |
G |
15: 35,640,544 |
S1352G |
probably benign |
Het |
| Zbtb38 |
C |
T |
9: 96,688,383 |
R216H |
probably damaging |
Het |
|
| Other mutations in Lrrc7 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00594:Lrrc7
|
APN |
3 |
158,187,010 (GRCm38) |
missense |
probably benign |
0.07 |
|
IGL00644:Lrrc7
|
APN |
3 |
158,202,368 (GRCm38) |
nonsense |
probably null |
|
|
IGL00822:Lrrc7
|
APN |
3 |
158,185,474 (GRCm38) |
missense |
probably damaging |
0.99 |
|
IGL00927:Lrrc7
|
APN |
3 |
158,161,090 (GRCm38) |
missense |
possibly damaging |
0.94 |
|
IGL00946:Lrrc7
|
APN |
3 |
158,161,356 (GRCm38) |
missense |
probably benign |
0.07 |
|
IGL00948:Lrrc7
|
APN |
3 |
158,161,557 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL01838:Lrrc7
|
APN |
3 |
158,185,463 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL01874:Lrrc7
|
APN |
3 |
158,240,443 (GRCm38) |
splice site |
probably benign |
|
|
IGL02514:Lrrc7
|
APN |
3 |
158,160,292 (GRCm38) |
missense |
probably damaging |
0.96 |
|
IGL02545:Lrrc7
|
APN |
3 |
158,185,374 (GRCm38) |
splice site |
probably benign |
|
|
IGL02665:Lrrc7
|
APN |
3 |
158,161,105 (GRCm38) |
missense |
probably damaging |
0.99 |
|
IGL03129:Lrrc7
|
APN |
3 |
158,161,059 (GRCm38) |
missense |
probably benign |
0.02 |
|
N/A:Lrrc7
|
UTSW |
3 |
158,160,340 (GRCm38) |
missense |
probably benign |
|
|
R0021:Lrrc7
|
UTSW |
3 |
158,160,661 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R0041:Lrrc7
|
UTSW |
3 |
158,164,260 (GRCm38) |
splice site |
probably benign |
|
|
R0255:Lrrc7
|
UTSW |
3 |
158,160,838 (GRCm38) |
nonsense |
probably null |
|
|
R0278:Lrrc7
|
UTSW |
3 |
158,179,795 (GRCm38) |
missense |
possibly damaging |
0.96 |
|
R0409:Lrrc7
|
UTSW |
3 |
158,161,426 (GRCm38) |
missense |
possibly damaging |
0.59 |
|
R0612:Lrrc7
|
UTSW |
3 |
158,164,353 (GRCm38) |
missense |
probably damaging |
0.98 |
|
R0866:Lrrc7
|
UTSW |
3 |
158,164,266 (GRCm38) |
splice site |
probably benign |
|
|
R1077:Lrrc7
|
UTSW |
3 |
158,161,143 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R1103:Lrrc7
|
UTSW |
3 |
158,148,706 (GRCm38) |
splice site |
probably benign |
|
|
R1157:Lrrc7
|
UTSW |
3 |
158,160,255 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R1187:Lrrc7
|
UTSW |
3 |
158,160,402 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R1301:Lrrc7
|
UTSW |
3 |
158,135,331 (GRCm38) |
missense |
probably benign |
0.20 |
|
R1433:Lrrc7
|
UTSW |
3 |
158,177,306 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R1450:Lrrc7
|
UTSW |
3 |
158,187,044 (GRCm38) |
missense |
possibly damaging |
0.62 |
|
R1595:Lrrc7
|
UTSW |
3 |
158,177,277 (GRCm38) |
nonsense |
probably null |
|
|
R1659:Lrrc7
|
UTSW |
3 |
158,161,408 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R1693:Lrrc7
|
UTSW |
3 |
158,084,533 (GRCm38) |
missense |
possibly damaging |
0.95 |
|
R1774:Lrrc7
|
UTSW |
3 |
158,160,292 (GRCm38) |
missense |
possibly damaging |
0.88 |
|
R2273:Lrrc7
|
UTSW |
3 |
158,187,059 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R2276:Lrrc7
|
UTSW |
3 |
158,179,792 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R2302:Lrrc7
|
UTSW |
3 |
158,135,244 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R2326:Lrrc7
|
UTSW |
3 |
158,170,661 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R2371:Lrrc7
|
UTSW |
3 |
158,161,060 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R2383:Lrrc7
|
UTSW |
3 |
158,163,956 (GRCm38) |
missense |
probably benign |
|
|
R2679:Lrrc7
|
UTSW |
3 |
158,175,108 (GRCm38) |
nonsense |
probably null |
|
|
R2698:Lrrc7
|
UTSW |
3 |
158,135,391 (GRCm38) |
missense |
probably benign |
0.22 |
|
R2858:Lrrc7
|
UTSW |
3 |
158,161,725 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R3758:Lrrc7
|
UTSW |
3 |
158,163,965 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R3791:Lrrc7
|
UTSW |
3 |
158,163,956 (GRCm38) |
missense |
probably benign |
|
|
R3805:Lrrc7
|
UTSW |
3 |
158,185,493 (GRCm38) |
missense |
probably benign |
0.10 |
|
R3806:Lrrc7
|
UTSW |
3 |
158,185,493 (GRCm38) |
missense |
probably benign |
0.10 |
|
R3807:Lrrc7
|
UTSW |
3 |
158,185,493 (GRCm38) |
missense |
probably benign |
0.10 |
|
R3892:Lrrc7
|
UTSW |
3 |
158,160,696 (GRCm38) |
missense |
probably benign |
0.08 |
|
R3912:Lrrc7
|
UTSW |
3 |
158,291,952 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R3913:Lrrc7
|
UTSW |
3 |
158,291,952 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R3963:Lrrc7
|
UTSW |
3 |
158,160,405 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4665:Lrrc7
|
UTSW |
3 |
158,318,408 (GRCm38) |
critical splice donor site |
probably benign |
|
|
R4671:Lrrc7
|
UTSW |
3 |
158,202,495 (GRCm38) |
critical splice acceptor site |
probably null |
|
|
R4688:Lrrc7
|
UTSW |
3 |
158,148,605 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4725:Lrrc7
|
UTSW |
3 |
158,318,408 (GRCm38) |
critical splice donor site |
probably benign |
|
|
R4726:Lrrc7
|
UTSW |
3 |
158,318,408 (GRCm38) |
critical splice donor site |
probably benign |
|
|
R4728:Lrrc7
|
UTSW |
3 |
158,318,408 (GRCm38) |
critical splice donor site |
probably benign |
|
|
R4783:Lrrc7
|
UTSW |
3 |
158,127,213 (GRCm38) |
critical splice donor site |
probably null |
|
|
R4867:Lrrc7
|
UTSW |
3 |
158,161,005 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4907:Lrrc7
|
UTSW |
3 |
158,161,240 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R5032:Lrrc7
|
UTSW |
3 |
158,181,580 (GRCm38) |
missense |
possibly damaging |
0.85 |
|
R5107:Lrrc7
|
UTSW |
3 |
158,161,896 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R5295:Lrrc7
|
UTSW |
3 |
158,170,739 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R5348:Lrrc7
|
UTSW |
3 |
158,175,326 (GRCm38) |
missense |
probably benign |
0.02 |
|
R5468:Lrrc7
|
UTSW |
3 |
158,318,436 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R5778:Lrrc7
|
UTSW |
3 |
158,170,743 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R5897:Lrrc7
|
UTSW |
3 |
158,164,353 (GRCm38) |
missense |
probably damaging |
0.98 |
|
R6179:Lrrc7
|
UTSW |
3 |
158,353,432 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R6312:Lrrc7
|
UTSW |
3 |
158,160,609 (GRCm38) |
missense |
probably benign |
0.04 |
|
R6313:Lrrc7
|
UTSW |
3 |
158,160,736 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R6366:Lrrc7
|
UTSW |
3 |
158,135,375 (GRCm38) |
missense |
probably benign |
0.04 |
|
R6389:Lrrc7
|
UTSW |
3 |
158,185,426 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R6638:Lrrc7
|
UTSW |
3 |
158,135,303 (GRCm38) |
missense |
probably benign |
0.20 |
|
R6956:Lrrc7
|
UTSW |
3 |
158,289,031 (GRCm38) |
missense |
probably benign |
0.02 |
|
R6969:Lrrc7
|
UTSW |
3 |
158,156,913 (GRCm38) |
missense |
probably benign |
0.19 |
|
R7073:Lrrc7
|
UTSW |
3 |
158,127,247 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R7313:Lrrc7
|
UTSW |
3 |
158,160,474 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R7365:Lrrc7
|
UTSW |
3 |
158,198,161 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R7398:Lrrc7
|
UTSW |
3 |
158,291,958 (GRCm38) |
nonsense |
probably null |
|
|
R7403:Lrrc7
|
UTSW |
3 |
158,148,674 (GRCm38) |
nonsense |
probably null |
|
|
R7407:Lrrc7
|
UTSW |
3 |
158,135,241 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R7427:Lrrc7
|
UTSW |
3 |
158,198,141 (GRCm38) |
missense |
probably benign |
0.06 |
|
R7453:Lrrc7
|
UTSW |
3 |
158,185,409 (GRCm38) |
missense |
probably benign |
0.00 |
|
R7461:Lrrc7
|
UTSW |
3 |
158,187,020 (GRCm38) |
missense |
probably benign |
0.00 |
|
R7807:Lrrc7
|
UTSW |
3 |
158,160,487 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R7872:Lrrc7
|
UTSW |
3 |
158,353,462 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R8215:Lrrc7
|
UTSW |
3 |
158,209,750 (GRCm38) |
missense |
probably benign |
|
|
R8367:Lrrc7
|
UTSW |
3 |
158,202,370 (GRCm38) |
missense |
possibly damaging |
0.80 |
|
R8867:Lrrc7
|
UTSW |
3 |
158,161,884 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R8880:Lrrc7
|
UTSW |
3 |
158,161,744 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R8941:Lrrc7
|
UTSW |
3 |
158,163,956 (GRCm38) |
missense |
probably benign |
|
|
R8958:Lrrc7
|
UTSW |
3 |
158,240,501 (GRCm38) |
missense |
probably benign |
0.02 |
|
R9068:Lrrc7
|
UTSW |
3 |
158,240,501 (GRCm38) |
missense |
probably benign |
0.02 |
|
R9069:Lrrc7
|
UTSW |
3 |
158,240,501 (GRCm38) |
missense |
probably benign |
0.02 |
|
R9180:Lrrc7
|
UTSW |
3 |
158,161,374 (GRCm38) |
missense |
possibly damaging |
0.61 |
|
R9193:Lrrc7
|
UTSW |
3 |
158,353,374 (GRCm38) |
nonsense |
probably null |
|
|
R9309:Lrrc7
|
UTSW |
3 |
158,209,724 (GRCm38) |
nonsense |
probably null |
|
|
R9418:Lrrc7
|
UTSW |
3 |
158,202,386 (GRCm38) |
missense |
possibly damaging |
0.66 |
|
R9474:Lrrc7
|
UTSW |
3 |
158,135,391 (GRCm38) |
missense |
probably benign |
0.22 |
|
R9515:Lrrc7
|
UTSW |
3 |
158,161,468 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R9635:Lrrc7
|
UTSW |
3 |
158,240,501 (GRCm38) |
missense |
probably benign |
0.02 |
|
R9639:Lrrc7
|
UTSW |
3 |
158,240,501 (GRCm38) |
missense |
probably benign |
0.02 |
|
R9682:Lrrc7
|
UTSW |
3 |
158,177,317 (GRCm38) |
missense |
possibly damaging |
0.92 |
|
R9731:Lrrc7
|
UTSW |
3 |
158,175,251 (GRCm38) |
missense |
probably benign |
|
|
| Predicted Primers |
PCR Primer
(F):5'- GCTCTGAAAATGAGGATGAACC -3'
(R):5'- TAAGTGAGTCTAGCCAAACTGTG -3'
Sequencing Primer
(F):5'- CTAGTAGAGGATGCAAAATGGTTTAG -3'
(R):5'- CCAAACTGTGGCCTAACTAGTGAG -3'
|
| Posted On |
2017-12-01 |
Incidental Mutation