Incidental Mutation 'R0130:Cr2'
| ID |
50092 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Cr2
|
| Ensembl Gene |
ENSMUSG00000026616 |
| Gene Name |
complement receptor 2 |
| Synonyms |
C3DR, CD21, Cr-1, Cr1, CD35, Cr-2 |
| MMRRC Submission |
038415-MU
|
| Accession Numbers |
|
| Essential gene? |
Probably non essential
(E-score: 0.140)
|
| Stock # |
R0130 (G1)
|
| Quality Score |
225 |
|
Status
|
Validated
(trace)
|
| Chromosome |
1 |
| Chromosomal Location |
195136811-195176716 bp(-) (GRCm38) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
A to T
at 195166231 bp (GRCm38)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Valine to Aspartic acid
at position 328
(V328D)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000147804
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000043104]
[ENSMUST00000082321]
[ENSMUST00000193801]
[ENSMUST00000195120]
[ENSMUST00000210219]
|
| AlphaFold |
no structure available at present |
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000043104
AA Change: V308D
PolyPhen 2
Score 0.819 (Sensitivity: 0.84; Specificity: 0.93)
|
| SMART Domains |
Protein: ENSMUSP00000044261
Gene: ENSMUSG00000026616
AA Change: V308D
| Domain | Start | End | E-Value | Type |
|---|
|
CCP
|
2 |
58 |
5.04e-7 |
SMART |
|
CCP
|
63 |
120 |
3.58e-12 |
SMART |
|
CCP
|
125 |
191 |
1.2e-13 |
SMART |
|
CCP
|
197 |
252 |
2.73e-17 |
SMART |
|
CCP
|
256 |
311 |
1.01e-15 |
SMART |
|
Blast:CCP
|
316 |
347 |
2e-13 |
BLAST |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000082321
|
| SMART Domains |
Protein: ENSMUSP00000080938
Gene: ENSMUSG00000026616
| Domain | Start | End | E-Value | Type |
|---|
|
CCP
|
23 |
82 |
1.01e-11 |
SMART |
|
CCP
|
91 |
147 |
9.1e-14 |
SMART |
|
CCP
|
155 |
211 |
1.9e-16 |
SMART |
|
CCP
|
216 |
272 |
1.6e-9 |
SMART |
|
CCP
|
277 |
343 |
1.01e-11 |
SMART |
|
CCP
|
352 |
407 |
1.2e-13 |
SMART |
|
CCP
|
411 |
467 |
2.34e-16 |
SMART |
|
CCP
|
472 |
523 |
1.24e0 |
SMART |
|
CCP
|
528 |
594 |
4.48e-13 |
SMART |
|
CCP
|
603 |
658 |
1.95e-13 |
SMART |
|
CCP
|
718 |
778 |
1.75e-15 |
SMART |
|
CCP
|
787 |
842 |
2.06e-12 |
SMART |
|
CCP
|
850 |
906 |
7.92e-14 |
SMART |
|
CCP
|
911 |
967 |
1.29e-13 |
SMART |
|
transmembrane domain
|
975 |
997 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000193801
|
| SMART Domains |
Protein: ENSMUSP00000141276
Gene: ENSMUSG00000026616
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
20 |
N/A |
INTRINSIC |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000194149
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000195120
|
| SMART Domains |
Protein: ENSMUSP00000141538
Gene: ENSMUSG00000026616
| Domain | Start | End | E-Value | Type |
|---|
|
CCP
|
23 |
82 |
4.9e-14 |
SMART |
|
CCP
|
91 |
147 |
4.5e-16 |
SMART |
|
CCP
|
155 |
211 |
9.1e-19 |
SMART |
|
CCP
|
216 |
272 |
8e-12 |
SMART |
|
CCP
|
277 |
343 |
5e-14 |
SMART |
|
CCP
|
352 |
407 |
5.9e-16 |
SMART |
|
CCP
|
411 |
467 |
1.1e-18 |
SMART |
|
CCP
|
472 |
523 |
6.1e-3 |
SMART |
|
CCP
|
528 |
594 |
2.2e-15 |
SMART |
|
CCP
|
603 |
658 |
9.4e-16 |
SMART |
|
CCP
|
718 |
778 |
8.3e-18 |
SMART |
|
CCP
|
787 |
842 |
1e-14 |
SMART |
|
CCP
|
850 |
906 |
4e-16 |
SMART |
|
CCP
|
911 |
967 |
6.2e-16 |
SMART |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000195347
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000195722
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000210219
AA Change: V328D
PolyPhen 2
Score 0.985 (Sensitivity: 0.74; Specificity: 0.96)
|
| Meta Mutation Damage Score |
0.6467 |
| Coding Region Coverage |
- 1x: 99.0%
- 3x: 97.7%
- 10x: 93.4%
- 20x: 80.2%
|
| Validation Efficiency |
99% (84/85) |
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene encodes a membrane protein, which functions as a receptor for Epstein-Barr virus (EBV) binding on B and T lymphocytes. Genetic variations in this gene are associated with susceptibility to systemic lupus erythematosus type 9 (SLEB9). Alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Sep 2009]
PHENOTYPE: Homozygotes for targeted null mutations exhibit impaired humoral immune responses to T cell-dependent antigens, with limited affinity maturation, and reduced memory B cell and germinal center formation. [provided by MGI curators]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 68 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Abcg8 |
A |
T |
17: 84,686,666 (GRCm38) |
Y37F |
probably damaging |
Het |
| Ablim2 |
G |
A |
5: 35,809,176 (GRCm38) |
|
probably benign |
Het |
| Anxa9 |
A |
G |
3: 95,302,422 (GRCm38) |
S129P |
probably benign |
Het |
| Apol7c |
A |
G |
15: 77,526,362 (GRCm38) |
I128T |
possibly damaging |
Het |
| Arfgef2 |
T |
G |
2: 166,835,719 (GRCm38) |
I88S |
probably damaging |
Het |
| Arfip2 |
A |
G |
7: 105,638,998 (GRCm38) |
|
probably benign |
Het |
| Atp5j2 |
A |
T |
5: 145,188,182 (GRCm38) |
|
probably benign |
Het |
| Atp7b |
C |
T |
8: 22,028,172 (GRCm38) |
E205K |
possibly damaging |
Het |
| Atp8b5 |
T |
A |
4: 43,369,715 (GRCm38) |
|
probably null |
Het |
| Cd22 |
A |
G |
7: 30,869,964 (GRCm38) |
Y402H |
possibly damaging |
Het |
| Cd248 |
A |
G |
19: 5,069,962 (GRCm38) |
T613A |
probably benign |
Het |
| Cdcp2 |
C |
T |
4: 107,106,707 (GRCm38) |
|
probably benign |
Het |
| Cenpc1 |
A |
T |
5: 86,046,546 (GRCm38) |
D120E |
probably benign |
Het |
| Chd3 |
T |
A |
11: 69,359,830 (GRCm38) |
H691L |
probably damaging |
Het |
| Colec12 |
C |
T |
18: 9,858,921 (GRCm38) |
P568L |
unknown |
Het |
| Cped1 |
T |
A |
6: 22,121,039 (GRCm38) |
Y373N |
probably benign |
Het |
| Ctnnd2 |
A |
T |
15: 30,921,913 (GRCm38) |
E895V |
probably damaging |
Het |
| D630045J12Rik |
A |
T |
6: 38,149,771 (GRCm38) |
|
probably benign |
Het |
| Dcdc2a |
A |
T |
13: 25,187,672 (GRCm38) |
|
probably benign |
Het |
| Dync1h1 |
C |
A |
12: 110,618,674 (GRCm38) |
T837K |
probably benign |
Het |
| Eif2ak3 |
C |
A |
6: 70,881,732 (GRCm38) |
|
probably benign |
Het |
| Epb41l5 |
A |
C |
1: 119,549,902 (GRCm38) |
V705G |
possibly damaging |
Het |
| Fat2 |
T |
A |
11: 55,252,118 (GRCm38) |
M4302L |
probably benign |
Het |
| Flnb |
T |
C |
14: 7,901,951 (GRCm38) |
V938A |
probably damaging |
Het |
| Frmd4a |
T |
C |
2: 4,604,092 (GRCm38) |
Y928H |
probably damaging |
Het |
| Fyn |
C |
T |
10: 39,511,982 (GRCm38) |
T78M |
probably benign |
Het |
| Gdap2 |
A |
G |
3: 100,201,995 (GRCm38) |
T443A |
probably damaging |
Het |
| Gde1 |
A |
T |
7: 118,695,060 (GRCm38) |
F63L |
probably benign |
Het |
| Gjc3 |
A |
G |
5: 137,957,940 (GRCm38) |
S28P |
probably benign |
Het |
| Gm10250 |
G |
A |
15: 5,120,991 (GRCm38) |
|
probably null |
Het |
| Gm1141 |
T |
C |
X: 71,939,555 (GRCm38) |
C378R |
possibly damaging |
Het |
| Hp1bp3 |
C |
T |
4: 138,237,209 (GRCm38) |
S348F |
probably damaging |
Het |
| Klhl23 |
T |
C |
2: 69,833,966 (GRCm38) |
V553A |
probably damaging |
Het |
| Lman2l |
G |
T |
1: 36,424,864 (GRCm38) |
S171* |
probably null |
Het |
| Lrp1b |
T |
C |
2: 41,511,508 (GRCm38) |
D378G |
probably damaging |
Het |
| Map3k11 |
T |
C |
19: 5,690,815 (GRCm38) |
L190P |
probably damaging |
Het |
| Mki67 |
T |
A |
7: 135,696,459 (GRCm38) |
Q2282L |
probably damaging |
Het |
| Mthfd2 |
T |
A |
6: 83,309,008 (GRCm38) |
I272F |
probably damaging |
Het |
| Myom1 |
A |
T |
17: 71,045,755 (GRCm38) |
D358V |
probably damaging |
Het |
| Nebl |
T |
A |
2: 17,393,023 (GRCm38) |
Q487H |
possibly damaging |
Het |
| Nebl |
T |
C |
2: 17,390,926 (GRCm38) |
|
probably benign |
Het |
| Nlrp2 |
T |
A |
7: 5,322,418 (GRCm38) |
N14Y |
possibly damaging |
Het |
| Olfr1090 |
T |
C |
2: 86,753,887 (GRCm38) |
M284V |
probably benign |
Het |
| Olfr304 |
T |
C |
7: 86,386,306 (GRCm38) |
Y118C |
probably damaging |
Het |
| Olfr339 |
T |
A |
2: 36,422,287 (GRCm38) |
D296E |
probably benign |
Het |
| Olfr372 |
C |
T |
8: 72,058,400 (GRCm38) |
T240M |
probably damaging |
Het |
| Olfr992 |
T |
A |
2: 85,399,961 (GRCm38) |
S191C |
probably damaging |
Het |
| Paxip1 |
C |
T |
5: 27,744,185 (GRCm38) |
|
probably benign |
Het |
| Pclo |
A |
G |
5: 14,679,797 (GRCm38) |
|
probably benign |
Het |
| Pld2 |
T |
G |
11: 70,554,348 (GRCm38) |
N591K |
probably benign |
Het |
| Plekha7 |
A |
G |
7: 116,170,704 (GRCm38) |
M276T |
probably damaging |
Het |
| Prss39 |
T |
A |
1: 34,502,200 (GRCm38) |
|
probably benign |
Het |
| Prtg |
A |
G |
9: 72,809,716 (GRCm38) |
Y113C |
probably damaging |
Het |
| Rab38 |
T |
A |
7: 88,450,541 (GRCm38) |
I88N |
probably damaging |
Het |
| Rbfox2 |
A |
G |
15: 77,091,857 (GRCm38) |
|
probably benign |
Het |
| Samd5 |
A |
G |
10: 9,674,939 (GRCm38) |
W9R |
probably damaging |
Het |
| Sec14l1 |
A |
T |
11: 117,156,407 (GRCm38) |
K637I |
possibly damaging |
Het |
| Sh2b1 |
A |
T |
7: 126,471,448 (GRCm38) |
D360E |
possibly damaging |
Het |
| Sh3bp4 |
A |
G |
1: 89,145,314 (GRCm38) |
N628S |
possibly damaging |
Het |
| Sim1 |
A |
T |
10: 50,907,961 (GRCm38) |
I104F |
probably damaging |
Het |
| Smcp |
T |
A |
3: 92,584,520 (GRCm38) |
T7S |
unknown |
Het |
| Sp4 |
A |
G |
12: 118,300,816 (GRCm38) |
|
probably benign |
Het |
| Tectb |
G |
T |
19: 55,181,961 (GRCm38) |
K81N |
probably damaging |
Het |
| Thbs4 |
G |
T |
13: 92,754,410 (GRCm38) |
H850N |
probably benign |
Het |
| Tiam1 |
T |
C |
16: 89,897,754 (GRCm38) |
M272V |
probably benign |
Het |
| Trav13-3 |
T |
A |
14: 53,729,776 (GRCm38) |
|
noncoding transcript |
Het |
| Ubap2l |
A |
T |
3: 90,021,373 (GRCm38) |
S478T |
possibly damaging |
Het |
| Vmn2r85 |
A |
G |
10: 130,419,185 (GRCm38) |
|
probably benign |
Het |
|
| Other mutations in Cr2 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00587:Cr2
|
APN |
1 |
195,154,251 (GRCm38) |
missense |
possibly damaging |
0.76 |
|
IGL01326:Cr2
|
APN |
1 |
195,141,221 (GRCm38) |
missense |
probably null |
1.00 |
|
IGL01358:Cr2
|
APN |
1 |
195,159,820 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL01410:Cr2
|
APN |
1 |
195,163,234 (GRCm38) |
missense |
possibly damaging |
0.49 |
|
IGL01468:Cr2
|
APN |
1 |
195,168,535 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL01608:Cr2
|
APN |
1 |
195,155,220 (GRCm38) |
missense |
possibly damaging |
0.50 |
|
IGL01810:Cr2
|
APN |
1 |
195,159,595 (GRCm38) |
missense |
possibly damaging |
0.49 |
|
IGL01843:Cr2
|
APN |
1 |
195,150,914 (GRCm38) |
splice site |
probably benign |
|
|
IGL02332:Cr2
|
APN |
1 |
195,160,322 (GRCm38) |
missense |
probably benign |
0.19 |
|
IGL02934:Cr2
|
APN |
1 |
195,154,325 (GRCm38) |
splice site |
probably benign |
|
|
IGL02938:Cr2
|
APN |
1 |
195,166,388 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL03149:Cr2
|
APN |
1 |
195,166,366 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL03327:Cr2
|
APN |
1 |
195,169,759 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL03346:Cr2
|
APN |
1 |
195,169,759 (GRCm38) |
missense |
probably damaging |
1.00 |
|
Pillar
|
UTSW |
1 |
195,155,888 (GRCm38) |
nonsense |
probably null |
|
|
PIT4354001:Cr2
|
UTSW |
1 |
195,166,309 (GRCm38) |
missense |
probably damaging |
1.00 |
|
PIT4418001:Cr2
|
UTSW |
1 |
195,157,452 (GRCm38) |
missense |
probably benign |
0.08 |
|
R0128:Cr2
|
UTSW |
1 |
195,166,231 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R0380:Cr2
|
UTSW |
1 |
195,157,407 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R0538:Cr2
|
UTSW |
1 |
195,160,359 (GRCm38) |
splice site |
probably benign |
|
|
R0605:Cr2
|
UTSW |
1 |
195,163,596 (GRCm38) |
splice site |
probably benign |
|
|
R0626:Cr2
|
UTSW |
1 |
195,171,111 (GRCm38) |
missense |
possibly damaging |
0.95 |
|
R1135:Cr2
|
UTSW |
1 |
195,157,190 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R1396:Cr2
|
UTSW |
1 |
195,169,253 (GRCm38) |
splice site |
probably null |
|
|
R1422:Cr2
|
UTSW |
1 |
195,171,125 (GRCm38) |
missense |
probably benign |
0.01 |
|
R1467:Cr2
|
UTSW |
1 |
195,157,509 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R1467:Cr2
|
UTSW |
1 |
195,157,509 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R1511:Cr2
|
UTSW |
1 |
195,155,272 (GRCm38) |
missense |
possibly damaging |
0.92 |
|
R1572:Cr2
|
UTSW |
1 |
195,163,314 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R1714:Cr2
|
UTSW |
1 |
195,151,686 (GRCm38) |
missense |
possibly damaging |
0.46 |
|
R1748:Cr2
|
UTSW |
1 |
195,155,905 (GRCm38) |
nonsense |
probably null |
|
|
R1761:Cr2
|
UTSW |
1 |
195,155,123 (GRCm38) |
critical splice donor site |
probably null |
|
|
R1824:Cr2
|
UTSW |
1 |
195,157,316 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R1893:Cr2
|
UTSW |
1 |
195,155,187 (GRCm38) |
missense |
probably benign |
0.03 |
|
R1990:Cr2
|
UTSW |
1 |
195,154,150 (GRCm38) |
missense |
possibly damaging |
0.63 |
|
R1991:Cr2
|
UTSW |
1 |
195,154,150 (GRCm38) |
missense |
possibly damaging |
0.63 |
|
R1992:Cr2
|
UTSW |
1 |
195,154,150 (GRCm38) |
missense |
possibly damaging |
0.63 |
|
R2191:Cr2
|
UTSW |
1 |
195,163,381 (GRCm38) |
missense |
possibly damaging |
0.94 |
|
R2276:Cr2
|
UTSW |
1 |
195,157,368 (GRCm38) |
missense |
possibly damaging |
0.94 |
|
R2277:Cr2
|
UTSW |
1 |
195,157,368 (GRCm38) |
missense |
possibly damaging |
0.94 |
|
R3548:Cr2
|
UTSW |
1 |
195,155,888 (GRCm38) |
nonsense |
probably null |
|
|
R3743:Cr2
|
UTSW |
1 |
195,149,966 (GRCm38) |
splice site |
probably benign |
|
|
R3941:Cr2
|
UTSW |
1 |
195,165,814 (GRCm38) |
missense |
probably damaging |
0.97 |
|
R3963:Cr2
|
UTSW |
1 |
195,159,739 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4211:Cr2
|
UTSW |
1 |
195,156,328 (GRCm38) |
missense |
probably damaging |
0.96 |
|
R4484:Cr2
|
UTSW |
1 |
195,154,174 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4546:Cr2
|
UTSW |
1 |
195,171,041 (GRCm38) |
missense |
possibly damaging |
0.94 |
|
R4791:Cr2
|
UTSW |
1 |
195,155,935 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4801:Cr2
|
UTSW |
1 |
195,163,311 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4802:Cr2
|
UTSW |
1 |
195,163,311 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4874:Cr2
|
UTSW |
1 |
195,176,570 (GRCm38) |
missense |
possibly damaging |
0.82 |
|
R4885:Cr2
|
UTSW |
1 |
195,158,731 (GRCm38) |
missense |
possibly damaging |
0.92 |
|
R4889:Cr2
|
UTSW |
1 |
195,176,585 (GRCm38) |
missense |
possibly damaging |
0.70 |
|
R5154:Cr2
|
UTSW |
1 |
195,159,446 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R5574:Cr2
|
UTSW |
1 |
195,141,236 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R5594:Cr2
|
UTSW |
1 |
195,157,190 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R5645:Cr2
|
UTSW |
1 |
195,154,273 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R5700:Cr2
|
UTSW |
1 |
195,159,757 (GRCm38) |
missense |
probably damaging |
0.96 |
|
R5929:Cr2
|
UTSW |
1 |
195,171,111 (GRCm38) |
missense |
possibly damaging |
0.91 |
|
R6237:Cr2
|
UTSW |
1 |
195,157,502 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R6299:Cr2
|
UTSW |
1 |
195,168,646 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R6368:Cr2
|
UTSW |
1 |
195,168,472 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R6406:Cr2
|
UTSW |
1 |
195,169,771 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R6618:Cr2
|
UTSW |
1 |
195,157,379 (GRCm38) |
missense |
probably damaging |
0.98 |
|
R6684:Cr2
|
UTSW |
1 |
195,171,021 (GRCm38) |
nonsense |
probably null |
|
|
R6720:Cr2
|
UTSW |
1 |
195,155,200 (GRCm38) |
missense |
probably damaging |
0.97 |
|
R6866:Cr2
|
UTSW |
1 |
195,151,691 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R6915:Cr2
|
UTSW |
1 |
195,171,146 (GRCm38) |
missense |
probably benign |
0.06 |
|
R7057:Cr2
|
UTSW |
1 |
195,151,610 (GRCm38) |
missense |
possibly damaging |
0.83 |
|
R7117:Cr2
|
UTSW |
1 |
195,160,601 (GRCm38) |
missense |
possibly damaging |
0.79 |
|
R7200:Cr2
|
UTSW |
1 |
195,163,249 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R7209:Cr2
|
UTSW |
1 |
195,168,724 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R7350:Cr2
|
UTSW |
1 |
195,155,286 (GRCm38) |
missense |
probably benign |
0.21 |
|
R7414:Cr2
|
UTSW |
1 |
195,150,036 (GRCm38) |
missense |
probably benign |
|
|
R7453:Cr2
|
UTSW |
1 |
195,165,257 (GRCm38) |
splice site |
probably null |
|
|
R7479:Cr2
|
UTSW |
1 |
195,158,410 (GRCm38) |
critical splice donor site |
probably null |
|
|
R7480:Cr2
|
UTSW |
1 |
195,154,176 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R7570:Cr2
|
UTSW |
1 |
195,169,340 (GRCm38) |
nonsense |
probably null |
|
|
R7666:Cr2
|
UTSW |
1 |
195,154,225 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R7921:Cr2
|
UTSW |
1 |
195,151,667 (GRCm38) |
missense |
possibly damaging |
0.94 |
|
R7923:Cr2
|
UTSW |
1 |
195,168,687 (GRCm38) |
missense |
probably benign |
0.03 |
|
R8396:Cr2
|
UTSW |
1 |
195,158,068 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R8503:Cr2
|
UTSW |
1 |
195,163,542 (GRCm38) |
missense |
probably benign |
|
|
R8517:Cr2
|
UTSW |
1 |
195,155,899 (GRCm38) |
missense |
probably benign |
0.03 |
|
R8773:Cr2
|
UTSW |
1 |
195,158,605 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R8849:Cr2
|
UTSW |
1 |
195,157,239 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R8896:Cr2
|
UTSW |
1 |
195,169,273 (GRCm38) |
missense |
possibly damaging |
0.58 |
|
R8938:Cr2
|
UTSW |
1 |
195,171,116 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R9027:Cr2
|
UTSW |
1 |
195,151,721 (GRCm38) |
missense |
probably benign |
0.08 |
|
R9045:Cr2
|
UTSW |
1 |
195,155,372 (GRCm38) |
missense |
possibly damaging |
0.61 |
|
R9116:Cr2
|
UTSW |
1 |
195,158,669 (GRCm38) |
nonsense |
probably null |
|
|
R9137:Cr2
|
UTSW |
1 |
195,168,332 (GRCm38) |
critical splice donor site |
probably null |
|
|
R9476:Cr2
|
UTSW |
1 |
195,158,108 (GRCm38) |
missense |
probably damaging |
0.97 |
|
R9497:Cr2
|
UTSW |
1 |
195,168,435 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R9510:Cr2
|
UTSW |
1 |
195,158,108 (GRCm38) |
missense |
probably damaging |
0.97 |
|
R9752:Cr2
|
UTSW |
1 |
195,141,267 (GRCm38) |
missense |
probably benign |
0.37 |
|
R9799:Cr2
|
UTSW |
1 |
195,160,680 (GRCm38) |
missense |
probably benign |
0.02 |
|
X0028:Cr2
|
UTSW |
1 |
195,149,982 (GRCm38) |
missense |
probably benign |
0.09 |
|
X0066:Cr2
|
UTSW |
1 |
195,166,321 (GRCm38) |
missense |
probably damaging |
0.99 |
|
Z1176:Cr2
|
UTSW |
1 |
195,154,153 (GRCm38) |
missense |
probably benign |
0.23 |
|
| Predicted Primers |
PCR Primer
(F):5'- GCTTGCACATGAAGAGTCAGGAAACTG -3'
(R):5'- TGGCCTTCCAAAGTGTGACACATTG -3'
Sequencing Primer
(F):5'- actgctccctctccacc -3'
(R):5'- CATTGGAGAAGGATACATTAATCCC -3'
|
| Posted On |
2013-06-12 |
Incidental Mutation