Mutagenetix > Incidental Mutation

Incidental Mutation 'R5657:Gm6647'

501236

Institutional Source

Beutler Lab

Gene Symbol

Gm6647

Ensembl Gene

ENSMUSG00000090991

Gene Name

predicted gene 6647

Synonyms

MMRRC Submission

043171-MU

Accession Numbers

Essential gene?

Not available question?

Stock #

R5657 (G1)

Quality Score

225

Status

Not validated

Chromosome

Chromosomal Location

13818676-13821901 bp(+) (GRCm39)

Type of Mutation

unclassified

DNA Base Change (assembly)

T to G at 13818835 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Gene Model

predicted gene model for transcript(s):

AlphaFold

no structure available at present

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000170514

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000199961

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000200620

Coding Region Coverage

1x: 99.3%
3x: 98.7%
10x: 97.4%
20x: 95.6%

Validation Efficiency

Allele List at MGI

Other mutations in this stock

Total: 38 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
Agbl5	A	G	5: 31,051,390 (GRCm39)	Y533C	probably damaging	Het
Ahnak	T	C	19: 8,991,979 (GRCm39)	V4421A	probably damaging	Het
Bach1	A	G	16: 87,516,173 (GRCm39)	K238R	probably benign	Het
Bloc1s6	T	A	2: 122,580,577 (GRCm39)	V12D	probably benign	Het
Clca3b	C	A	3: 144,533,144 (GRCm39)	L629F	probably benign	Het
Clhc1	A	G	11: 29,511,431 (GRCm39)	I292V	probably benign	Het
Col27a1	T	C	4: 63,143,547 (GRCm39)	S412P	probably damaging	Het
Col6a4	A	G	9: 105,949,397 (GRCm39)	I746T	probably damaging	Het
Cracr2a	G	A	6: 127,580,970 (GRCm39)	A49T	probably damaging	Het
Cyb561d1	A	G	3: 108,108,008 (GRCm39)	I28T	possibly damaging	Het
Dnah11	T	A	12: 117,847,352 (GRCm39)	M4264L	probably damaging	Het
Dnajc13	A	G	9: 104,105,736 (GRCm39)	L412S	probably damaging	Het
Dpf3	T	C	12: 83,371,785 (GRCm39)	N150S	probably damaging	Het
Epha2	T	C	4: 141,050,805 (GRCm39)	C854R	probably damaging	Het
Fat2	G	T	11: 55,201,507 (GRCm39)	Y522*	probably null	Het
Foxm1	A	T	6: 128,350,351 (GRCm39)	S551C	possibly damaging	Het
Galnt12	T	C	4: 47,104,150 (GRCm39)	V136A	possibly damaging	Het
Grin2b	T	A	6: 135,710,085 (GRCm39)	I1154F	possibly damaging	Het
Hmcn1	A	G	1: 150,534,313 (GRCm39)	V2987A	probably benign	Het
Jade2	A	G	11: 51,707,814 (GRCm39)	S800P	probably damaging	Het
Naip6	C	A	13: 100,436,909 (GRCm39)	S538I	probably benign	Het
Or1e33	T	C	11: 73,738,366 (GRCm39)	N195S	probably damaging	Het
Plekha6	G	C	1: 133,200,045 (GRCm39)	R208P	possibly damaging	Het
Plod1	T	C	4: 148,003,238 (GRCm39)	E529G	possibly damaging	Het
Plppr2	T	C	9: 21,858,911 (GRCm39)	C343R	probably damaging	Het
Prpf38a	T	C	4: 108,425,621 (GRCm39)	D219G	probably damaging	Het
Ptpra	G	A	2: 130,346,204 (GRCm39)	E122K	probably benign	Het
Rabl2	T	C	15: 89,472,416 (GRCm39)	M38V	probably benign	Het
Reep1	A	G	6: 71,738,358 (GRCm39)	M39V	possibly damaging	Het
Rsf1	GC	GCGGCGGCGTC	7: 97,229,141 (GRCm39)		probably benign	Het
Slc26a10	T	C	10: 127,010,833 (GRCm39)		probably benign	Het
Sun2	C	A	15: 79,612,150 (GRCm39)	E510*	probably null	Het
Tanc1	A	G	2: 59,665,051 (GRCm39)		probably null	Het
Ticam1	TCACACA	TCACA	17: 56,577,629 (GRCm39)		probably null	Het
Tor1aip1	G	T	1: 155,883,234 (GRCm39)	H205N	probably damaging	Het
Trpc6	C	T	9: 8,609,808 (GRCm39)	T92I	probably benign	Het
Vmn2r100	T	A	17: 19,725,178 (GRCm39)	F36I	probably benign	Het
Zfp787	T	C	7: 6,136,053 (GRCm39)	Y66C	probably damaging	Het

Predicted Primers

PCR Primer
(F):5'- TTTCTTGGTGGACTGCCTAC -3'
(R):5'- TGACCAAGCTTCAGGTTCTG -3'

Sequencing Primer
(F):5'- GTGGACTGCCTACACTGCTTG -3'
(R):5'- AGGTTCTGCCTCTCCACTATGAAG -3'

Posted On

2017-12-01