Incidental Mutation 'IGL01063:4930444P10Rik'
ID50176
Institutional Source Australian Phenomics Network (link to record)
Gene Symbol 4930444P10Rik
Ensembl Gene ENSMUSG00000067795
Gene NameRIKEN cDNA 4930444P10 gene
Synonyms
Accession Numbers
Is this an essential gene? Probably non essential (E-score: 0.069) question?
Stock #IGL01063
Quality Score
Status
Chromosome1
Chromosomal Location16065979-16093325 bp(-) (GRCm38)
Type of Mutationnonsense
DNA Base Change (assembly) A to T at 16078646 bp
ZygosityHeterozygous
Amino Acid Change Leucine to Stop codon at position 61 (L61*)
Ref Sequence ENSEMBL: ENSMUSP00000119257 (fasta)
Gene Model predicted gene model for transcript(s): [ENSMUST00000115367] [ENSMUST00000145070] [ENSMUST00000151004]
Predicted Effect probably null
Transcript: ENSMUST00000115367
AA Change: L92*
SMART Domains Protein: ENSMUSP00000111024
Gene: ENSMUSG00000067795
AA Change: L92*

DomainStartEndE-ValueType
low complexity region 93 100 N/A INTRINSIC
low complexity region 172 184 N/A INTRINSIC
Predicted Effect probably null
Transcript: ENSMUST00000145070
AA Change: L61*
SMART Domains Protein: ENSMUSP00000137853
Gene: ENSMUSG00000067795
AA Change: L61*

DomainStartEndE-ValueType
low complexity region 62 69 N/A INTRINSIC
low complexity region 141 153 N/A INTRINSIC
Predicted Effect probably null
Transcript: ENSMUST00000151004
AA Change: L61*
SMART Domains Protein: ENSMUSP00000119257
Gene: ENSMUSG00000067795
AA Change: L61*

DomainStartEndE-ValueType
low complexity region 62 69 N/A INTRINSIC
low complexity region 141 153 N/A INTRINSIC
Coding Region Coverage
Validation Efficiency
Allele List at MGI
Other mutations in this stock
Total: 47 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
1110038F14Rik G A 15: 76,950,275 V124I probably damaging Het
Abca7 T C 10: 80,011,297 I1705T probably damaging Het
Ablim1 T A 19: 57,061,328 I393F probably damaging Het
Adamts5 A G 16: 85,899,834 L145P probably damaging Het
Ano6 T C 15: 95,948,429 I537T probably damaging Het
AU018091 T C 7: 3,162,313 I190V possibly damaging Het
Camk1 T A 6: 113,338,372 D155V probably damaging Het
Cdh6 A C 15: 13,064,495 I103S probably damaging Het
Cntnap1 A G 11: 101,181,788 D537G probably benign Het
Col6a3 T C 1: 90,802,332 K1144E probably damaging Het
Cpeb1 T A 7: 81,372,181 E71D probably benign Het
Cps1 T C 1: 67,195,166 L904P possibly damaging Het
Cyfip1 T A 7: 55,904,210 F700I probably damaging Het
Dmp1 G A 5: 104,207,099 M1I probably null Het
Efcab6 A T 15: 84,054,512 M1K probably null Het
Extl2 A T 3: 116,027,482 H312L possibly damaging Het
Fat4 C A 3: 38,890,579 A1207D possibly damaging Het
Flnb T C 14: 7,926,518 probably benign Het
Hdac10 G T 15: 89,123,868 A593E possibly damaging Het
Hdhd2 T C 18: 76,965,273 probably null Het
Kcnq2 A G 2: 181,109,789 probably benign Het
Kdm7a A G 6: 39,165,130 F405L probably damaging Het
Lypd6b C A 2: 49,943,630 probably benign Het
Mki67 A T 7: 135,694,922 D2794E possibly damaging Het
Mtmr14 T A 6: 113,266,326 F40I probably damaging Het
Olfr131 G T 17: 38,082,653 S108R possibly damaging Het
Olfr213 T A 6: 116,541,007 C185S probably damaging Het
Olfr476 A T 7: 107,967,534 I46F probably damaging Het
Olfr986 A T 9: 40,187,756 I214F probably benign Het
Ppargc1a C A 5: 51,474,322 V322L probably benign Het
Ppfibp1 T A 6: 147,029,697 M917K probably benign Het
Prkg2 C T 5: 98,969,936 probably null Het
Rfx4 A G 10: 84,868,382 E296G possibly damaging Het
Rfx8 T A 1: 39,682,950 K292* probably null Het
Scamp3 C A 3: 89,177,666 probably benign Het
Scn4a A T 11: 106,330,364 I823N possibly damaging Het
Sdk2 A G 11: 113,830,842 V1316A probably damaging Het
Setd2 T C 9: 110,573,673 V1794A probably damaging Het
Stard8 G T X: 99,073,088 R983L probably damaging Het
Tbc1d23 A T 16: 57,192,675 D311E probably benign Het
Tex21 T C 12: 76,198,818 H568R probably benign Het
Tex35 T C 1: 157,105,097 probably benign Het
Tgs1 T A 4: 3,591,292 F442I possibly damaging Het
Traf2 C A 2: 25,524,919 C303F probably benign Het
Trim56 A T 5: 137,114,500 V54D possibly damaging Het
Yars2 C T 16: 16,306,542 R338* probably null Het
Zfp668 A T 7: 127,866,282 C577S probably damaging Het
Other mutations in 4930444P10Rik
AlleleSourceChrCoordTypePredicted EffectPPH Score
R1777:4930444P10Rik UTSW 1 16078589 missense possibly damaging 0.77
R4992:4930444P10Rik UTSW 1 16080877 missense probably damaging 0.98
R4999:4930444P10Rik UTSW 1 16068798 critical splice donor site probably null
R5229:4930444P10Rik UTSW 1 16080959 utr 5 prime probably benign
Z1177:4930444P10Rik UTSW 1 16082022 intron probably benign
Posted On2013-06-21