Incidental Mutation 'R6185:Myo10'
| ID |
502129 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Myo10
|
| Ensembl Gene |
ENSMUSG00000022272 |
| Gene Name |
myosin X |
| Synonyms |
myosin-X, D15Ertd600e |
| MMRRC Submission |
044325-MU
|
| Accession Numbers |
|
| Essential gene? |
Non essential
(E-score: 0.000)
|
| Stock # |
R6185 (G1)
|
| Quality Score |
225.009 |
|
Status
|
Validated
|
| Chromosome |
15 |
| Chromosomal Location |
25622636-25813759 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
T to G
at 25726596 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Phenylalanine to Cysteine
at position 273
(F273C)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000118280
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000110457]
[ENSMUST00000137601]
|
| AlphaFold |
F8VQB6 |
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000110457
AA Change: F306C
PolyPhen 2
Score 0.948 (Sensitivity: 0.79; Specificity: 0.95)
|
| SMART Domains |
Protein: ENSMUSP00000106087
Gene: ENSMUSG00000022272
AA Change: F306C
| Domain | Start | End | E-Value | Type |
|---|
|
MYSc
|
57 |
740 |
N/A |
SMART |
|
IQ
|
741 |
763 |
1.27e-3 |
SMART |
|
IQ
|
764 |
786 |
1.06e0 |
SMART |
|
IQ
|
787 |
809 |
7.07e-2 |
SMART |
|
Pfam:MYO10_CC
|
881 |
932 |
4.2e-22 |
PFAM |
|
low complexity region
|
959 |
981 |
N/A |
INTRINSIC |
|
low complexity region
|
1090 |
1102 |
N/A |
INTRINSIC |
|
low complexity region
|
1147 |
1165 |
N/A |
INTRINSIC |
|
PH
|
1217 |
1316 |
1.39e-21 |
SMART |
|
PH
|
1397 |
1503 |
6.76e-11 |
SMART |
|
MyTH4
|
1551 |
1699 |
4.12e-37 |
SMART |
|
B41
|
1700 |
1962 |
1.72e-44 |
SMART |
|
low complexity region
|
2050 |
2062 |
N/A |
INTRINSIC |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000126076
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000130517
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000137601
AA Change: F273C
PolyPhen 2
Score 0.988 (Sensitivity: 0.73; Specificity: 0.96)
|
| SMART Domains |
Protein: ENSMUSP00000118280
Gene: ENSMUSG00000022272
AA Change: F273C
| Domain | Start | End | E-Value | Type |
|---|
|
MYSc
|
24 |
707 |
N/A |
SMART |
|
IQ
|
708 |
730 |
1.27e-3 |
SMART |
|
IQ
|
731 |
753 |
1.06e0 |
SMART |
|
IQ
|
754 |
776 |
7.07e-2 |
SMART |
|
| Meta Mutation Damage Score |
0.8711 |
| Coding Region Coverage |
- 1x: 100.0%
- 3x: 100.0%
- 10x: 99.7%
- 20x: 99.1%
|
| Validation Efficiency |
96% (80/83) |
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene encodes a member of the myosin superfamily. The protein represents an unconventional myosin; it should not be confused with the conventional non-muscle myosin-10 (MYH10). Unconventional myosins contain the basic domains of conventional myosins and are further distinguished from class members by their tail domains. This gene functions as an actin-based molecular motor and plays a role in integration of F-actin and microtubule cytoskeletons during meiosis. [provided by RefSeq, Dec 2011]
PHENOTYPE: Homozygous null mutations are semi-lethal with over half of homozygous embryos exhibiting exencephaly. Surviving mutants show decreased body weight, white spotting, syndactyly, persistence of hyaloid vascular system and other eye defects. [provided by MGI curators]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 81 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Abca1 |
A |
T |
4: 53,078,089 (GRCm39) |
H894Q |
probably benign |
Het |
| Abca4 |
A |
T |
3: 121,919,789 (GRCm39) |
I1024F |
probably damaging |
Het |
| Acadl |
A |
G |
1: 66,877,522 (GRCm39) |
V343A |
possibly damaging |
Het |
| Akr1e1 |
T |
A |
13: 4,651,252 (GRCm39) |
I123L |
probably benign |
Het |
| Angptl2 |
T |
C |
2: 33,119,026 (GRCm39) |
S267P |
probably benign |
Het |
| Ap2a1 |
T |
G |
7: 44,565,594 (GRCm39) |
K91T |
probably damaging |
Het |
| Bend7 |
A |
T |
2: 4,793,333 (GRCm39) |
Q379L |
probably damaging |
Het |
| Bicdl1 |
C |
T |
5: 115,808,212 (GRCm39) |
|
probably null |
Het |
| Cachd1 |
C |
A |
4: 100,838,228 (GRCm39) |
Y830* |
probably null |
Het |
| Ccdc158 |
T |
A |
5: 92,814,713 (GRCm39) |
I38F |
possibly damaging |
Het |
| Cep97 |
T |
A |
16: 55,735,455 (GRCm39) |
M448L |
probably benign |
Het |
| Chd9 |
A |
G |
8: 91,775,765 (GRCm39) |
D2572G |
probably damaging |
Het |
| Clcnkb |
C |
T |
4: 141,141,825 (GRCm39) |
V54M |
probably benign |
Het |
| Cln8 |
A |
G |
8: 14,946,544 (GRCm39) |
D186G |
probably benign |
Het |
| Crxos |
C |
T |
7: 15,636,805 (GRCm39) |
S22L |
possibly damaging |
Het |
| Cx3cr1 |
A |
T |
9: 119,880,444 (GRCm39) |
H319Q |
probably benign |
Het |
| Cyp2j6 |
G |
C |
4: 96,424,323 (GRCm39) |
L145V |
probably damaging |
Het |
| Dmrta1 |
A |
G |
4: 89,580,005 (GRCm39) |
R322G |
probably damaging |
Het |
| Dpf1 |
A |
G |
7: 29,010,696 (GRCm39) |
E103G |
possibly damaging |
Het |
| Dsg1b |
T |
G |
18: 20,532,543 (GRCm39) |
V529G |
probably benign |
Het |
| Dst |
G |
A |
1: 34,212,161 (GRCm39) |
V1361I |
probably damaging |
Het |
| Epha4 |
T |
C |
1: 77,483,743 (GRCm39) |
I89V |
probably damaging |
Het |
| Etfdh |
G |
T |
3: 79,513,114 (GRCm39) |
H370N |
probably benign |
Het |
| Fam186a |
A |
G |
15: 99,845,530 (GRCm39) |
I238T |
unknown |
Het |
| Fbxl5 |
T |
A |
5: 43,978,894 (GRCm39) |
S19C |
probably benign |
Het |
| Fkbpl |
G |
A |
17: 34,864,303 (GRCm39) |
A24T |
probably benign |
Het |
| Fryl |
A |
G |
5: 73,270,131 (GRCm39) |
V367A |
probably benign |
Het |
| Gm19410 |
T |
A |
8: 36,274,664 (GRCm39) |
L1495H |
possibly damaging |
Het |
| Gm19965 |
A |
G |
1: 116,749,003 (GRCm39) |
E228G |
possibly damaging |
Het |
| Gpr89 |
C |
A |
3: 96,798,149 (GRCm39) |
C169F |
probably damaging |
Het |
| Hmcn1 |
A |
T |
1: 150,491,189 (GRCm39) |
|
probably null |
Het |
| Hsph1 |
A |
T |
5: 149,541,160 (GRCm39) |
C753S |
probably damaging |
Het |
| Igf2 |
T |
A |
7: 142,212,118 (GRCm39) |
S4C |
possibly damaging |
Het |
| Kansl3 |
A |
T |
1: 36,385,099 (GRCm39) |
S486T |
probably damaging |
Het |
| Khdrbs1 |
G |
C |
4: 129,636,068 (GRCm39) |
|
probably benign |
Het |
| Lnx1 |
A |
T |
5: 74,846,269 (GRCm39) |
C60* |
probably null |
Het |
| Lrpprc |
T |
C |
17: 85,074,452 (GRCm39) |
D485G |
probably benign |
Het |
| Ly6i |
A |
T |
15: 74,851,879 (GRCm39) |
S97T |
possibly damaging |
Het |
| Me2 |
G |
A |
18: 73,924,199 (GRCm39) |
Q338* |
probably null |
Het |
| Med16 |
A |
T |
10: 79,732,197 (GRCm39) |
L790Q |
probably damaging |
Het |
| Muc16 |
G |
T |
9: 18,565,769 (GRCm39) |
T2250K |
unknown |
Het |
| Neil3 |
T |
A |
8: 54,052,182 (GRCm39) |
H472L |
probably benign |
Het |
| Nrxn1 |
T |
A |
17: 90,344,564 (GRCm39) |
S57C |
probably damaging |
Het |
| Nup188 |
A |
T |
2: 30,231,722 (GRCm39) |
T1439S |
probably damaging |
Het |
| Or10g3 |
T |
C |
14: 52,610,019 (GRCm39) |
T164A |
possibly damaging |
Het |
| Or10g7 |
T |
C |
9: 39,905,420 (GRCm39) |
F105L |
probably benign |
Het |
| Or5w10 |
A |
G |
2: 87,375,087 (GRCm39) |
M267T |
possibly damaging |
Het |
| Otud7a |
T |
A |
7: 63,408,133 (GRCm39) |
L812Q |
probably damaging |
Het |
| Paip2b |
C |
T |
6: 83,786,952 (GRCm39) |
A95T |
probably benign |
Het |
| Pax4 |
C |
T |
6: 28,446,347 (GRCm39) |
V49I |
probably damaging |
Het |
| Plek |
C |
T |
11: 16,931,829 (GRCm39) |
A341T |
probably damaging |
Het |
| Prkag1 |
G |
A |
15: 98,723,595 (GRCm39) |
P10L |
probably benign |
Het |
| R3hdm1 |
A |
C |
1: 128,079,598 (GRCm39) |
D15A |
possibly damaging |
Het |
| Rad54b |
A |
T |
4: 11,593,804 (GRCm39) |
D144V |
possibly damaging |
Het |
| Rmi2 |
C |
T |
16: 10,704,073 (GRCm39) |
T138I |
probably benign |
Het |
| Sbf1 |
A |
G |
15: 89,189,814 (GRCm39) |
L379P |
probably damaging |
Het |
| Sec14l3 |
A |
T |
11: 4,025,244 (GRCm39) |
I285F |
probably damaging |
Het |
| Sec31b |
A |
T |
19: 44,531,723 (GRCm39) |
I62N |
possibly damaging |
Het |
| Selp |
A |
G |
1: 163,953,915 (GRCm39) |
N72D |
probably damaging |
Het |
| Sipa1l1 |
T |
A |
12: 82,471,802 (GRCm39) |
S1261T |
probably damaging |
Het |
| Sipa1l2 |
A |
T |
8: 126,194,992 (GRCm39) |
Y915* |
probably null |
Het |
| Slc22a27 |
A |
T |
19: 7,903,953 (GRCm39) |
D61E |
probably benign |
Het |
| Slc2a7 |
A |
G |
4: 150,233,450 (GRCm39) |
T8A |
probably benign |
Het |
| Slc5a2 |
T |
C |
7: 127,870,349 (GRCm39) |
I529T |
probably damaging |
Het |
| Spart |
A |
C |
3: 55,024,640 (GRCm39) |
Q78H |
probably damaging |
Het |
| Spocd1 |
T |
C |
4: 129,850,242 (GRCm39) |
I756T |
probably benign |
Het |
| Stc1 |
G |
A |
14: 69,275,813 (GRCm39) |
C202Y |
probably damaging |
Het |
| Stk10 |
A |
G |
11: 32,527,749 (GRCm39) |
T166A |
probably benign |
Het |
| Syt6 |
A |
T |
3: 103,492,844 (GRCm39) |
D32V |
probably damaging |
Het |
| Tanc1 |
T |
A |
2: 59,621,929 (GRCm39) |
|
probably null |
Het |
| Tanc2 |
T |
A |
11: 105,803,865 (GRCm39) |
N297K |
probably damaging |
Het |
| Telo2 |
A |
G |
17: 25,321,014 (GRCm39) |
S734P |
probably benign |
Het |
| Tfrc |
T |
A |
16: 32,437,090 (GRCm39) |
Y250N |
probably benign |
Het |
| Tmem97 |
C |
T |
11: 78,434,388 (GRCm39) |
W65* |
probably null |
Het |
| Ubr3 |
T |
C |
2: 69,768,621 (GRCm39) |
M476T |
probably damaging |
Het |
| Ubtf |
T |
C |
11: 102,204,849 (GRCm39) |
T117A |
probably damaging |
Het |
| Usp17lb |
T |
A |
7: 104,490,631 (GRCm39) |
M99L |
probably benign |
Het |
| Uvrag |
A |
C |
7: 98,790,039 (GRCm39) |
|
probably null |
Het |
| Vmn2r63 |
A |
G |
7: 42,578,435 (GRCm39) |
S153P |
probably damaging |
Het |
| Vmn2r90 |
A |
T |
17: 17,953,644 (GRCm39) |
T603S |
probably damaging |
Het |
| Vps8 |
C |
A |
16: 21,288,891 (GRCm39) |
L417I |
probably damaging |
Het |
|
| Other mutations in Myo10 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00557:Myo10
|
APN |
15 |
25,776,466 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01068:Myo10
|
APN |
15 |
25,739,395 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
IGL01352:Myo10
|
APN |
15 |
25,701,783 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01388:Myo10
|
APN |
15 |
25,736,703 (GRCm39) |
missense |
possibly damaging |
0.55 |
|
IGL01460:Myo10
|
APN |
15 |
25,714,194 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL01553:Myo10
|
APN |
15 |
25,776,415 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01732:Myo10
|
APN |
15 |
25,732,149 (GRCm39) |
missense |
probably benign |
0.10 |
|
IGL01992:Myo10
|
APN |
15 |
25,799,634 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
IGL02000:Myo10
|
APN |
15 |
25,808,152 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02045:Myo10
|
APN |
15 |
25,726,574 (GRCm39) |
missense |
probably benign |
0.03 |
|
IGL02307:Myo10
|
APN |
15 |
25,776,401 (GRCm39) |
splice site |
probably benign |
|
|
IGL02511:Myo10
|
APN |
15 |
25,723,975 (GRCm39) |
missense |
probably damaging |
0.97 |
|
IGL03240:Myo10
|
APN |
15 |
25,701,688 (GRCm39) |
missense |
probably damaging |
1.00 |
|
least
|
UTSW |
15 |
25,726,561 (GRCm39) |
nonsense |
probably null |
|
|
R0037:Myo10
|
UTSW |
15 |
25,666,618 (GRCm39) |
intron |
probably benign |
|
|
R0153:Myo10
|
UTSW |
15 |
25,781,324 (GRCm39) |
missense |
possibly damaging |
0.84 |
|
R0282:Myo10
|
UTSW |
15 |
25,793,253 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0360:Myo10
|
UTSW |
15 |
25,804,454 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0585:Myo10
|
UTSW |
15 |
25,736,541 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0617:Myo10
|
UTSW |
15 |
25,738,091 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0729:Myo10
|
UTSW |
15 |
25,722,243 (GRCm39) |
splice site |
probably benign |
|
|
R0771:Myo10
|
UTSW |
15 |
25,778,264 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0960:Myo10
|
UTSW |
15 |
25,801,275 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1562:Myo10
|
UTSW |
15 |
25,780,497 (GRCm39) |
missense |
possibly damaging |
0.81 |
|
R1651:Myo10
|
UTSW |
15 |
25,742,455 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1789:Myo10
|
UTSW |
15 |
25,726,611 (GRCm39) |
critical splice donor site |
probably null |
|
|
R1816:Myo10
|
UTSW |
15 |
25,800,286 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1835:Myo10
|
UTSW |
15 |
25,805,673 (GRCm39) |
missense |
possibly damaging |
0.53 |
|
R1908:Myo10
|
UTSW |
15 |
25,801,308 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2082:Myo10
|
UTSW |
15 |
25,786,079 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2101:Myo10
|
UTSW |
15 |
25,722,345 (GRCm39) |
missense |
probably benign |
0.26 |
|
R2129:Myo10
|
UTSW |
15 |
25,781,885 (GRCm39) |
missense |
probably benign |
0.09 |
|
R2141:Myo10
|
UTSW |
15 |
25,714,194 (GRCm39) |
missense |
probably benign |
|
|
R2142:Myo10
|
UTSW |
15 |
25,714,194 (GRCm39) |
missense |
probably benign |
|
|
R2920:Myo10
|
UTSW |
15 |
25,801,226 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2938:Myo10
|
UTSW |
15 |
25,795,803 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R3723:Myo10
|
UTSW |
15 |
25,803,374 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3852:Myo10
|
UTSW |
15 |
25,779,712 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4162:Myo10
|
UTSW |
15 |
25,726,501 (GRCm39) |
splice site |
probably null |
|
|
R4163:Myo10
|
UTSW |
15 |
25,726,501 (GRCm39) |
splice site |
probably null |
|
|
R4164:Myo10
|
UTSW |
15 |
25,726,501 (GRCm39) |
splice site |
probably null |
|
|
R4177:Myo10
|
UTSW |
15 |
25,734,137 (GRCm39) |
missense |
possibly damaging |
0.81 |
|
R4409:Myo10
|
UTSW |
15 |
25,807,955 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4667:Myo10
|
UTSW |
15 |
25,793,239 (GRCm39) |
missense |
possibly damaging |
0.91 |
|
R4905:Myo10
|
UTSW |
15 |
25,800,298 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R4933:Myo10
|
UTSW |
15 |
25,781,204 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R4968:Myo10
|
UTSW |
15 |
25,808,270 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5081:Myo10
|
UTSW |
15 |
25,786,026 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5123:Myo10
|
UTSW |
15 |
25,726,569 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R5310:Myo10
|
UTSW |
15 |
25,778,164 (GRCm39) |
splice site |
probably null |
|
|
R6073:Myo10
|
UTSW |
15 |
25,736,728 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6117:Myo10
|
UTSW |
15 |
25,805,745 (GRCm39) |
missense |
probably benign |
0.00 |
|
R6749:Myo10
|
UTSW |
15 |
25,714,196 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6819:Myo10
|
UTSW |
15 |
25,781,496 (GRCm39) |
missense |
possibly damaging |
0.80 |
|
R6875:Myo10
|
UTSW |
15 |
25,805,745 (GRCm39) |
missense |
probably benign |
0.00 |
|
R6908:Myo10
|
UTSW |
15 |
25,804,469 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6963:Myo10
|
UTSW |
15 |
25,734,149 (GRCm39) |
missense |
probably benign |
0.31 |
|
R7144:Myo10
|
UTSW |
15 |
25,724,011 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7266:Myo10
|
UTSW |
15 |
25,783,067 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7380:Myo10
|
UTSW |
15 |
25,779,706 (GRCm39) |
missense |
probably benign |
0.01 |
|
R7460:Myo10
|
UTSW |
15 |
25,807,913 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7614:Myo10
|
UTSW |
15 |
25,701,709 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7618:Myo10
|
UTSW |
15 |
25,726,561 (GRCm39) |
nonsense |
probably null |
|
|
R7717:Myo10
|
UTSW |
15 |
25,732,056 (GRCm39) |
missense |
probably benign |
0.01 |
|
R7811:Myo10
|
UTSW |
15 |
25,804,610 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7830:Myo10
|
UTSW |
15 |
25,738,057 (GRCm39) |
nonsense |
probably null |
|
|
R7862:Myo10
|
UTSW |
15 |
25,666,522 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8232:Myo10
|
UTSW |
15 |
25,804,400 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R8264:Myo10
|
UTSW |
15 |
25,800,195 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R8377:Myo10
|
UTSW |
15 |
25,804,481 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R8385:Myo10
|
UTSW |
15 |
25,804,484 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8426:Myo10
|
UTSW |
15 |
25,799,576 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R8439:Myo10
|
UTSW |
15 |
25,725,158 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8696:Myo10
|
UTSW |
15 |
25,799,572 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8775:Myo10
|
UTSW |
15 |
25,800,145 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R8775-TAIL:Myo10
|
UTSW |
15 |
25,800,145 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R8970:Myo10
|
UTSW |
15 |
25,803,467 (GRCm39) |
missense |
possibly damaging |
0.82 |
|
R9024:Myo10
|
UTSW |
15 |
25,793,295 (GRCm39) |
missense |
possibly damaging |
0.53 |
|
R9196:Myo10
|
UTSW |
15 |
25,805,716 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R9224:Myo10
|
UTSW |
15 |
25,808,081 (GRCm39) |
missense |
probably benign |
0.33 |
|
R9308:Myo10
|
UTSW |
15 |
25,781,862 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R9358:Myo10
|
UTSW |
15 |
25,781,520 (GRCm39) |
missense |
possibly damaging |
0.69 |
|
R9606:Myo10
|
UTSW |
15 |
25,776,401 (GRCm39) |
frame shift |
probably null |
|
|
R9722:Myo10
|
UTSW |
15 |
25,801,227 (GRCm39) |
missense |
probably damaging |
1.00 |
|
RF013:Myo10
|
UTSW |
15 |
25,799,565 (GRCm39) |
missense |
probably damaging |
0.99 |
|
Z1177:Myo10
|
UTSW |
15 |
25,799,640 (GRCm39) |
critical splice donor site |
probably null |
|
|
Z1177:Myo10
|
UTSW |
15 |
25,781,487 (GRCm39) |
missense |
probably damaging |
1.00 |
|
| Predicted Primers |
PCR Primer
(F):5'- AGAATAGAGTCTTCAGTGTACTCAGG -3'
(R):5'- AAAGCAGGCTTCCCTCTGAC -3'
Sequencing Primer
(F):5'- CAGTGTACTCAGGTAAATTACAGTG -3'
(R):5'- GCTTCCCTCTGACTTACAGGAAAAG -3'
|
| Posted On |
2018-02-27 |
Incidental Mutation