Mutagenetix > Incidental Mutation

Incidental Mutation 'R6190:Arhgef10l'

502455

Institutional Source

Beutler Lab

Gene Symbol

Arhgef10l

Ensembl Gene

ENSMUSG00000040964

Gene Name

Rho guanine nucleotide exchange factor 10-like

Synonyms

2810441C07Rik

MMRRC Submission

044330-MU

Accession Numbers

Essential gene?

Probably non essential (E-score: 0.085) question?

Stock #

R6190 (G1)

Quality Score

225.009

Status

Not validated

Chromosome

Chromosomal Location

140241796-140393318 bp(-) (GRCm39)

Type of Mutation

missense

DNA Base Change (assembly)

G to A at 140270073 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Threonine to Methionine at position 865 (T865M)

Ref Sequence

ENSEMBL: ENSMUSP00000095431 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000039204] [ENSMUST00000069623] [ENSMUST00000097820] [ENSMUST00000105797] [ENSMUST00000105798] [ENSMUST00000105799] [ENSMUST00000140403]

AlphaFold

A2AWP8

Predicted Effect

possibly damaging
Transcript: ENSMUST00000039204
AA Change: T904M

PolyPhen 2 Score 0.634 (Sensitivity: 0.87; Specificity: 0.91)

SMART Domains

Protein: ENSMUSP00000040531
Gene: ENSMUSG00000040964
AA Change: T904M

Domain	Start	End	E-Value	Type
low complexity region	10	25	N/A	INTRINSIC
low complexity region	28	49	N/A	INTRINSIC
low complexity region	78	89	N/A	INTRINSIC
low complexity region	105	116	N/A	INTRINSIC
low complexity region	170	184	N/A	INTRINSIC
RhoGEF	318	500	1.95e-52	SMART
Blast:PH	535	748	3e-82	BLAST
low complexity region	821	833	N/A	INTRINSIC
low complexity region	864	876	N/A	INTRINSIC
Blast:WD40	1217	1270	8e-18	BLAST

Predicted Effect

possibly damaging
Transcript: ENSMUST00000069623
AA Change: T870M

PolyPhen 2 Score 0.634 (Sensitivity: 0.87; Specificity: 0.91)

SMART Domains

Protein: ENSMUSP00000066249
Gene: ENSMUSG00000040964
AA Change: T870M

Domain	Start	End	E-Value	Type
low complexity region	10	25	N/A	INTRINSIC
low complexity region	28	49	N/A	INTRINSIC
low complexity region	78	89	N/A	INTRINSIC
low complexity region	105	116	N/A	INTRINSIC
low complexity region	170	184	N/A	INTRINSIC
RhoGEF	279	461	1.95e-52	SMART
Blast:PH	496	714	5e-80	BLAST
low complexity region	787	799	N/A	INTRINSIC
low complexity region	830	842	N/A	INTRINSIC
Blast:WD40	1183	1236	7e-18	BLAST

Predicted Effect

possibly damaging
Transcript: ENSMUST00000097820
AA Change: T865M

PolyPhen 2 Score 0.904 (Sensitivity: 0.82; Specificity: 0.94)

SMART Domains

Protein: ENSMUSP00000095431
Gene: ENSMUSG00000040964
AA Change: T865M

Domain	Start	End	E-Value	Type
low complexity region	10	25	N/A	INTRINSIC
low complexity region	28	49	N/A	INTRINSIC
low complexity region	78	89	N/A	INTRINSIC
low complexity region	105	116	N/A	INTRINSIC
low complexity region	170	184	N/A	INTRINSIC
RhoGEF	279	461	1.95e-52	SMART
Blast:PH	496	709	3e-82	BLAST
low complexity region	782	794	N/A	INTRINSIC
low complexity region	825	837	N/A	INTRINSIC
Blast:WD40	1178	1231	6e-18	BLAST

Predicted Effect

possibly damaging
Transcript: ENSMUST00000105797
AA Change: T617M

PolyPhen 2 Score 0.465 (Sensitivity: 0.89; Specificity: 0.90)

SMART Domains

Protein: ENSMUSP00000101423
Gene: ENSMUSG00000040964
AA Change: T617M

Domain	Start	End	E-Value	Type
low complexity region	50	62	N/A	INTRINSIC
Pfam:RhoGEF	101	183	7.1e-15	PFAM
low complexity region	195	213	N/A	INTRINSIC
Blast:PH	248	461	7e-83	BLAST
low complexity region	534	546	N/A	INTRINSIC
low complexity region	577	589	N/A	INTRINSIC
Blast:WD40	618	656	6e-15	BLAST
Blast:WD40	930	983	1e-17	BLAST

Predicted Effect

probably benign
Transcript: ENSMUST00000105798
AA Change: T669M

PolyPhen 2 Score 0.332 (Sensitivity: 0.90; Specificity: 0.89)

SMART Domains

Protein: ENSMUSP00000101424
Gene: ENSMUSG00000040964
AA Change: T669M

Domain	Start	End	E-Value	Type
RhoGEF	78	260	1.95e-52	SMART
Blast:PH	295	513	8e-81	BLAST
low complexity region	586	598	N/A	INTRINSIC
low complexity region	629	641	N/A	INTRINSIC
Blast:WD40	982	1035	6e-18	BLAST

Predicted Effect

possibly damaging
Transcript: ENSMUST00000105799
AA Change: T909M

PolyPhen 2 Score 0.501 (Sensitivity: 0.88; Specificity: 0.90)

SMART Domains

Protein: ENSMUSP00000101425
Gene: ENSMUSG00000040964
AA Change: T909M

Domain	Start	End	E-Value	Type
low complexity region	10	25	N/A	INTRINSIC
low complexity region	28	49	N/A	INTRINSIC
low complexity region	78	89	N/A	INTRINSIC
low complexity region	105	116	N/A	INTRINSIC
low complexity region	170	184	N/A	INTRINSIC
RhoGEF	318	500	1.95e-52	SMART
Blast:PH	535	753	5e-80	BLAST
low complexity region	826	838	N/A	INTRINSIC
low complexity region	869	881	N/A	INTRINSIC
Blast:WD40	1222	1275	8e-18	BLAST

Predicted Effect

unknown
Transcript: ENSMUST00000138493
AA Change: T449M

SMART Domains

Protein: ENSMUSP00000119471
Gene: ENSMUSG00000040964
AA Change: T449M

Domain	Start	End	E-Value	Type
Pfam:RhoGEF	1	46	3.1e-11	PFAM
Blast:PH	81	294	3e-86	BLAST
low complexity region	367	379	N/A	INTRINSIC
Blast:WD40	387	446	8e-6	BLAST
Blast:WD40	451	489	3e-15	BLAST

Predicted Effect

probably benign
Transcript: ENSMUST00000140403

SMART Domains

Protein: ENSMUSP00000117038
Gene: ENSMUSG00000040964

Domain	Start	End	E-Value	Type
low complexity region	2	14	N/A	INTRINSIC
Blast:PH	16	127	3e-57	BLAST

Coding Region Coverage

1x: 100.0%
3x: 99.9%
10x: 99.6%
20x: 98.8%

Validation Efficiency

MGI Phenotype

FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene belongs to the RhoGEF subfamily of RhoGTPases. Members of this subfamily are activated by specific guanine nucleotide exchange factors (GEFs) and are involved in signal transduction. The encoded protein shows cytosolic distribution. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2016]

Allele List at MGI

Other mutations in this stock

Total: 97 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
Abat	T	A	16: 8,423,472 (GRCm39)	L224Q	probably damaging	Het
Abcc5	A	G	16: 20,211,529 (GRCm39)	M478T	probably benign	Het
Acot10	T	C	15: 20,665,871 (GRCm39)	D290G	possibly damaging	Het
Actr3b	A	G	5: 26,036,688 (GRCm39)	Q167R	probably benign	Het
Actr8	C	T	14: 29,713,674 (GRCm39)	R565*	probably null	Het
Adcy7	C	T	8: 89,052,358 (GRCm39)		probably null	Het
Adgrb3	C	T	1: 25,459,728 (GRCm39)	V576I	probably benign	Het
Adgrv1	T	A	13: 81,607,882 (GRCm39)		probably null	Het
Adgrv1	A	T	13: 81,672,898 (GRCm39)		probably null	Het
Ak2	A	G	4: 128,892,976 (GRCm39)	D45G	probably damaging	Het
Ak9	C	G	10: 41,298,403 (GRCm39)	Q1489E	unknown	Het
Ak9	A	T	10: 41,298,404 (GRCm39)	Q1489L	unknown	Het
Akap12	C	A	10: 4,306,268 (GRCm39)	S1026Y	possibly damaging	Het
Ankhd1	T	G	18: 36,744,862 (GRCm39)	S601A	possibly damaging	Het
Apba2	A	T	7: 64,389,628 (GRCm39)	E508V	probably damaging	Het
Arhgap18	A	G	10: 26,722,031 (GRCm39)	M1V	probably null	Het
Bdh1	T	A	16: 31,268,715 (GRCm39)	V150D	probably damaging	Het
Becn1	A	G	11: 101,186,200 (GRCm39)	C135R	probably damaging	Het
C2cd4d	A	G	3: 94,271,226 (GRCm39)	D164G	probably benign	Het
Cacna1e	C	A	1: 154,362,316 (GRCm39)	V424F	possibly damaging	Het
Capn7	C	A	14: 31,085,560 (GRCm39)	T511K	probably benign	Het
Cdc5l	G	A	17: 45,718,943 (GRCm39)	P558S	probably benign	Het
Cep170	T	A	1: 176,609,975 (GRCm39)	H112L	probably damaging	Het
Cfap61	C	T	2: 145,789,053 (GRCm39)	T19M	probably benign	Het
Clca3a1	A	G	3: 144,463,821 (GRCm39)	V152A	probably benign	Het
Cnot10	G	T	9: 114,461,791 (GRCm39)	T24K	probably damaging	Het
Cntnap5b	T	A	1: 100,306,800 (GRCm39)	I839N	possibly damaging	Het
Cyp4f13	A	T	17: 33,148,847 (GRCm39)	D299E	probably damaging	Het
Dclk1	A	G	3: 55,395,232 (GRCm39)	E128G	probably damaging	Het
Dennd1b	T	C	1: 139,061,413 (GRCm39)	I365T	probably damaging	Het
Dgcr8	T	C	16: 18,102,274 (GRCm39)	T3A	probably damaging	Het
Dld	A	C	12: 31,394,847 (GRCm39)	I58S	probably damaging	Het
Dlg5	T	A	14: 24,240,506 (GRCm39)	R248S	probably damaging	Het
Eml2	G	A	7: 18,935,088 (GRCm39)	V432I	probably damaging	Het
Faf1	C	T	4: 109,719,012 (GRCm39)	L373F	probably damaging	Het
Fam171b	C	T	2: 83,707,042 (GRCm39)	T304I	probably benign	Het
Fcgrt	A	T	7: 44,751,622 (GRCm39)		probably null	Het
Gimap9	T	C	6: 48,655,285 (GRCm39)	W291R	probably damaging	Het
Gm4847	G	A	1: 166,457,892 (GRCm39)	A487V	probably damaging	Het
Gria4	T	A	9: 4,420,199 (GRCm39)	I888F	probably benign	Het
Hapln2	T	A	3: 87,930,600 (GRCm39)	I224F	probably damaging	Het
Herc1	T	G	9: 66,283,663 (GRCm39)	L332R	possibly damaging	Het
Hmgxb4	T	C	8: 75,749,927 (GRCm39)	V481A	probably benign	Het
Htr1d	T	C	4: 136,170,109 (GRCm39)	S113P	probably damaging	Het
Ift81	T	C	5: 122,689,163 (GRCm39)	Q651R	probably benign	Het
Il17ra	T	C	6: 120,452,234 (GRCm39)	S199P	probably damaging	Het
Itih2	T	C	2: 10,103,318 (GRCm39)	N723S	probably benign	Het
Jak1	A	T	4: 101,032,325 (GRCm39)	V427E	probably damaging	Het
Krt23	C	T	11: 99,376,584 (GRCm39)	D191N	probably damaging	Het
Lingo1	T	A	9: 56,526,934 (GRCm39)	I552F	possibly damaging	Het
Llgl2	G	A	11: 115,737,812 (GRCm39)	R199Q	probably benign	Het
Lrrc37a	G	T	11: 103,392,042 (GRCm39)	Q1128K	possibly damaging	Het
Lrrc74a	T	C	12: 86,783,263 (GRCm39)	V36A	probably benign	Het
M1ap	T	A	6: 82,980,877 (GRCm39)	D254E	possibly damaging	Het
Mal2	C	T	15: 54,434,794 (GRCm39)		probably benign	Het
Mbnl2	A	G	14: 120,622,833 (GRCm39)	T124A	probably benign	Het
Nfatc1	A	G	18: 80,755,885 (GRCm39)	S33P	probably benign	Het
Nfkbid	A	G	7: 30,125,162 (GRCm39)	N253S	probably damaging	Het
Ngfr	T	A	11: 95,465,267 (GRCm39)	I194F	probably benign	Het
Nhsl1	A	G	10: 18,345,789 (GRCm39)		probably benign	Het
Nol9	T	A	4: 152,125,691 (GRCm39)	I214N	possibly damaging	Het
Or1o3	A	G	17: 37,573,635 (GRCm39)	S307P	probably benign	Het
Or5p56	T	C	7: 107,590,307 (GRCm39)	L245P	probably damaging	Het
Or8k3	T	A	2: 86,058,578 (GRCm39)	T246S	possibly damaging	Het
Pax3	C	T	1: 78,169,186 (GRCm39)	S160N	possibly damaging	Het
Pde3b	A	G	7: 114,122,267 (GRCm39)		probably null	Het
Pde5a	A	C	3: 122,522,956 (GRCm39)	E21A	probably benign	Het
Plcxd1	A	G	5: 110,250,469 (GRCm39)	E270G	probably damaging	Het
Plxna1	T	A	6: 89,333,586 (GRCm39)	K348*	probably null	Het
Pramel34	A	T	5: 93,785,937 (GRCm39)	N114K	probably benign	Het
Prb1b	T	A	6: 132,289,692 (GRCm39)	H44L	unknown	Het
Psg21	G	T	7: 18,388,926 (GRCm39)	D55E	possibly damaging	Het
Rasa1	C	A	13: 85,381,814 (GRCm39)	A493S	probably benign	Het
Raver2	A	G	4: 100,990,814 (GRCm39)	I396V	probably benign	Het
Rpa2	A	G	4: 132,502,331 (GRCm39)	K138E	probably benign	Het
Rsad1	T	C	11: 94,439,062 (GRCm39)	N133D	probably damaging	Het
Rusc1	T	C	3: 88,999,188 (GRCm39)	D198G	probably benign	Het
Samsn1	A	T	16: 75,667,803 (GRCm39)	Y258N	probably damaging	Het
Scap	A	G	9: 110,203,135 (GRCm39)	N270D	probably benign	Het
Shisal2a	A	T	4: 108,225,052 (GRCm39)	I170N	probably damaging	Het
Smpd4	T	C	16: 17,449,877 (GRCm39)	Y200H	probably damaging	Het
Steap2	A	G	5: 5,725,881 (GRCm39)	V381A	probably damaging	Het
Syk	C	T	13: 52,765,089 (GRCm39)	T72I	probably damaging	Het
Tbc1d14	T	C	5: 36,729,228 (GRCm39)	D66G	possibly damaging	Het
Tcp11	A	G	17: 28,290,691 (GRCm39)	Y223H	probably benign	Het
Timm9	A	G	12: 71,173,124 (GRCm39)	S8P	probably benign	Het
Tmpo	T	C	10: 91,000,069 (GRCm39)		probably null	Het
Vezf1	T	C	11: 87,967,012 (GRCm39)	M81T	probably benign	Het
Vipr1	T	A	9: 121,493,719 (GRCm39)	W257R	probably damaging	Het
Vmn1r237	G	A	17: 21,534,556 (GRCm39)	G93D	probably damaging	Het
Vmn2r6	A	G	3: 64,445,424 (GRCm39)	V678A	probably benign	Het
Vmn2r85	T	C	10: 130,261,330 (GRCm39)	T336A	possibly damaging	Het
Xpnpep3	C	A	15: 81,322,300 (GRCm39)	D296E	probably benign	Het
Zfp35	C	A	18: 24,137,118 (GRCm39)	H487Q	probably benign	Het
Zfp606	A	T	7: 12,227,928 (GRCm39)	Y625F	probably damaging	Het
Zfp677	A	G	17: 21,617,530 (GRCm39)	T196A	possibly damaging	Het
Zmym1	T	C	4: 126,941,677 (GRCm39)	I904V	probably damaging	Het

Other mutations in Arhgef10l

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL01420:Arhgef10l	APN	4	140,297,649 (GRCm39)	missense	probably damaging	0.98
IGL01732:Arhgef10l	APN	4	140,307,726 (GRCm39)	missense	probably damaging	0.99
IGL01988:Arhgef10l	APN	4	140,305,672 (GRCm39)	splice site	probably benign
IGL02031:Arhgef10l	APN	4	140,302,656 (GRCm39)	missense	probably damaging	1.00
IGL02253:Arhgef10l	APN	4	140,271,595 (GRCm39)	nonsense	probably null
IGL02445:Arhgef10l	APN	4	140,274,318 (GRCm39)	missense	probably benign	0.19
IGL02619:Arhgef10l	APN	4	140,321,504 (GRCm39)	missense	probably benign	0.07
IGL02798:Arhgef10l	APN	4	140,292,441 (GRCm39)	critical splice donor site	probably null
IGL03064:Arhgef10l	APN	4	140,306,590 (GRCm39)	missense	probably damaging	1.00
IGL03178:Arhgef10l	APN	4	140,271,739 (GRCm39)	missense	possibly damaging	0.92
IGL03236:Arhgef10l	APN	4	140,338,671 (GRCm39)	missense	probably damaging	1.00
IGL03352:Arhgef10l	APN	4	140,311,242 (GRCm39)	start codon destroyed	probably null	0.99
PIT4494001:Arhgef10l	UTSW	4	140,292,522 (GRCm39)	missense	probably damaging	0.98
R0057:Arhgef10l	UTSW	4	140,338,529 (GRCm39)	splice site	probably benign
R0062:Arhgef10l	UTSW	4	140,279,843 (GRCm39)	missense	probably damaging	1.00
R0109:Arhgef10l	UTSW	4	140,305,605 (GRCm39)	missense	probably benign	0.02
R0109:Arhgef10l	UTSW	4	140,305,605 (GRCm39)	missense	probably benign	0.02
R0114:Arhgef10l	UTSW	4	140,311,194 (GRCm39)	missense	probably benign	0.17
R0334:Arhgef10l	UTSW	4	140,311,237 (GRCm39)	nonsense	probably null
R0742:Arhgef10l	UTSW	4	140,264,156 (GRCm39)	missense	probably damaging	1.00
R1017:Arhgef10l	UTSW	4	140,242,617 (GRCm39)	missense	probably damaging	0.99
R1166:Arhgef10l	UTSW	4	140,302,581 (GRCm39)	unclassified	probably benign
R1397:Arhgef10l	UTSW	4	140,271,754 (GRCm39)	missense	probably damaging	0.98
R1521:Arhgef10l	UTSW	4	140,242,749 (GRCm39)	missense	possibly damaging	0.95
R1707:Arhgef10l	UTSW	4	140,291,600 (GRCm39)	missense	probably damaging	1.00
R1793:Arhgef10l	UTSW	4	140,242,684 (GRCm39)	missense	probably damaging	0.97
R2018:Arhgef10l	UTSW	4	140,271,695 (GRCm39)	missense	probably damaging	1.00
R2093:Arhgef10l	UTSW	4	140,297,601 (GRCm39)	missense	possibly damaging	0.57
R2098:Arhgef10l	UTSW	4	140,306,743 (GRCm39)	missense	probably damaging	1.00
R2310:Arhgef10l	UTSW	4	140,320,429 (GRCm39)	missense	probably damaging	1.00
R2879:Arhgef10l	UTSW	4	140,242,598 (GRCm39)	missense	probably benign	0.09
R2883:Arhgef10l	UTSW	4	140,244,113 (GRCm39)	missense	probably benign	0.02
R3732:Arhgef10l	UTSW	4	140,308,930 (GRCm39)	small deletion	probably benign
R3732:Arhgef10l	UTSW	4	140,308,930 (GRCm39)	small deletion	probably benign
R3861:Arhgef10l	UTSW	4	140,242,798 (GRCm39)	missense	possibly damaging	0.94
R4049:Arhgef10l	UTSW	4	140,242,762 (GRCm39)	missense	probably benign	0.05
R4322:Arhgef10l	UTSW	4	140,270,037 (GRCm39)	missense	probably benign	0.07
R4707:Arhgef10l	UTSW	4	140,264,194 (GRCm39)	missense	possibly damaging	0.63
R5395:Arhgef10l	UTSW	4	140,297,601 (GRCm39)	missense	probably benign	0.16
R5720:Arhgef10l	UTSW	4	140,308,930 (GRCm39)	small deletion	probably benign
R6066:Arhgef10l	UTSW	4	140,304,391 (GRCm39)	missense	probably damaging	1.00
R6464:Arhgef10l	UTSW	4	140,314,126 (GRCm39)	missense	probably benign	0.05
R6476:Arhgef10l	UTSW	4	140,338,693 (GRCm39)	missense	probably damaging	1.00
R6478:Arhgef10l	UTSW	4	140,270,068 (GRCm39)	missense	possibly damaging	0.91
R6483:Arhgef10l	UTSW	4	140,344,226 (GRCm39)	missense	probably damaging	0.99
R6631:Arhgef10l	UTSW	4	140,245,058 (GRCm39)	intron	probably benign
R6721:Arhgef10l	UTSW	4	140,297,655 (GRCm39)	missense	probably damaging	1.00
R6890:Arhgef10l	UTSW	4	140,271,730 (GRCm39)	missense	probably damaging	1.00
R7098:Arhgef10l	UTSW	4	140,308,222 (GRCm39)	missense	probably benign	0.01
R7100:Arhgef10l	UTSW	4	140,244,126 (GRCm39)	missense	possibly damaging	0.60
R7117:Arhgef10l	UTSW	4	140,291,497 (GRCm39)	critical splice donor site	probably null
R7195:Arhgef10l	UTSW	4	140,338,721 (GRCm39)	missense	probably benign
R7222:Arhgef10l	UTSW	4	140,248,580 (GRCm39)	missense	probably damaging	1.00
R7397:Arhgef10l	UTSW	4	140,290,115 (GRCm39)	missense	probably damaging	1.00
R7776:Arhgef10l	UTSW	4	140,302,642 (GRCm39)	missense	probably damaging	1.00
R7801:Arhgef10l	UTSW	4	140,271,578 (GRCm39)	missense	probably benign	0.00
R7811:Arhgef10l	UTSW	4	140,242,335 (GRCm39)	missense	possibly damaging	0.63
R7832:Arhgef10l	UTSW	4	140,305,616 (GRCm39)	missense	possibly damaging	0.90
R7849:Arhgef10l	UTSW	4	140,311,245 (GRCm39)	critical splice acceptor site	probably null
R7963:Arhgef10l	UTSW	4	140,306,736 (GRCm39)	missense	probably damaging	1.00
R8434:Arhgef10l	UTSW	4	140,291,582 (GRCm39)	missense	possibly damaging	0.89
R8943:Arhgef10l	UTSW	4	140,292,550 (GRCm39)	missense	probably damaging	0.99
R9004:Arhgef10l	UTSW	4	140,279,921 (GRCm39)	missense	probably damaging	0.98
R9006:Arhgef10l	UTSW	4	140,271,659 (GRCm39)	missense	probably benign	0.04
R9033:Arhgef10l	UTSW	4	140,321,463 (GRCm39)	missense	probably damaging	0.99
R9302:Arhgef10l	UTSW	4	140,242,548 (GRCm39)	missense	probably benign	0.04
R9337:Arhgef10l	UTSW	4	140,338,624 (GRCm39)	missense	probably damaging	1.00
R9375:Arhgef10l	UTSW	4	140,319,265 (GRCm39)	missense	probably benign
R9454:Arhgef10l	UTSW	4	140,308,236 (GRCm39)	nonsense	probably null
Z1088:Arhgef10l	UTSW	4	140,309,046 (GRCm39)	missense	possibly damaging	0.53
Z1177:Arhgef10l	UTSW	4	140,244,083 (GRCm39)	missense	probably benign	0.28

Predicted Primers

PCR Primer
(F):5'- TGTTTGATCTCTTAGCAGAGGATC -3'
(R):5'- TGGATTTGAACTCAGCTCTGGG -3'

Sequencing Primer
(F):5'- CTTAGCAGAGGATCCAGGTTTAACC -3'
(R):5'- GTGGCATTGGAACTCGGTAC -3'

Posted On

2018-02-27