Incidental Mutation 'R6190:Plxna1'
| ID |
502465 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Plxna1
|
| Ensembl Gene |
ENSMUSG00000030084 |
| Gene Name |
plexin A1 |
| Synonyms |
NOV, PlexA1, Plxn1, 2600013D04Rik |
| MMRRC Submission |
044330-MU
|
| Accession Numbers |
|
| Essential gene? |
Probably essential
(E-score: 0.895)
|
| Stock # |
R6190 (G1)
|
| Quality Score |
225.009 |
|
Status
|
Not validated
|
| Chromosome |
6 |
| Chromosomal Location |
89293295-89339595 bp(-) (GRCm39) |
| Type of Mutation |
nonsense |
| DNA Base Change (assembly) |
T to A
at 89333586 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Lysine to Stop codon
at position 348
(K348*)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000131840
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000049845]
[ENSMUST00000163139]
|
| AlphaFold |
P70206 |
| Predicted Effect |
probably null
Transcript: ENSMUST00000049845
AA Change: K348*
|
| SMART Domains |
Protein: ENSMUSP00000063066
Gene: ENSMUSG00000030084
AA Change: K348*
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
27 |
N/A |
INTRINSIC |
|
Sema
|
49 |
494 |
7.43e-126 |
SMART |
|
PSI
|
512 |
562 |
6.4e-11 |
SMART |
|
PSI
|
658 |
705 |
9.78e-7 |
SMART |
|
low complexity region
|
759 |
772 |
N/A |
INTRINSIC |
|
PSI
|
806 |
860 |
7.24e-10 |
SMART |
|
IPT
|
861 |
957 |
3.2e-26 |
SMART |
|
IPT
|
958 |
1043 |
1.59e-21 |
SMART |
|
IPT
|
1045 |
1145 |
6.86e-26 |
SMART |
|
IPT
|
1147 |
1242 |
1.64e-5 |
SMART |
|
transmembrane domain
|
1243 |
1265 |
N/A |
INTRINSIC |
|
Pfam:Plexin_cytopl
|
1316 |
1864 |
8.8e-263 |
PFAM |
|
| Predicted Effect |
probably null
Transcript: ENSMUST00000163139
AA Change: K348*
|
| SMART Domains |
Protein: ENSMUSP00000131840
Gene: ENSMUSG00000030084
AA Change: K348*
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
27 |
N/A |
INTRINSIC |
|
Sema
|
49 |
494 |
7.43e-126 |
SMART |
|
PSI
|
512 |
562 |
6.4e-11 |
SMART |
|
PSI
|
658 |
705 |
9.78e-7 |
SMART |
|
low complexity region
|
759 |
772 |
N/A |
INTRINSIC |
|
PSI
|
806 |
860 |
7.24e-10 |
SMART |
|
IPT
|
861 |
957 |
3.2e-26 |
SMART |
|
IPT
|
958 |
1043 |
1.59e-21 |
SMART |
|
IPT
|
1045 |
1145 |
6.86e-26 |
SMART |
|
IPT
|
1147 |
1242 |
1.64e-5 |
SMART |
|
transmembrane domain
|
1243 |
1265 |
N/A |
INTRINSIC |
|
Pfam:Plexin_cytopl
|
1315 |
1864 |
2.5e-264 |
PFAM |
|
| Coding Region Coverage |
- 1x: 100.0%
- 3x: 99.9%
- 10x: 99.6%
- 20x: 98.8%
|
| Validation Efficiency |
|
| MGI Phenotype |
PHENOTYPE: Mice homozygous for a null allele exhibit bone cellularity abnormalities, altered dendritic cell physiology, abnormal proprioceptive and oligodendrocyte morphology, and increased lymphatic branching complexity and LEC numbers. [provided by MGI curators]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 97 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Abat |
T |
A |
16: 8,423,472 (GRCm39) |
L224Q |
probably damaging |
Het |
| Abcc5 |
A |
G |
16: 20,211,529 (GRCm39) |
M478T |
probably benign |
Het |
| Acot10 |
T |
C |
15: 20,665,871 (GRCm39) |
D290G |
possibly damaging |
Het |
| Actr3b |
A |
G |
5: 26,036,688 (GRCm39) |
Q167R |
probably benign |
Het |
| Actr8 |
C |
T |
14: 29,713,674 (GRCm39) |
R565* |
probably null |
Het |
| Adcy7 |
C |
T |
8: 89,052,358 (GRCm39) |
|
probably null |
Het |
| Adgrb3 |
C |
T |
1: 25,459,728 (GRCm39) |
V576I |
probably benign |
Het |
| Adgrv1 |
T |
A |
13: 81,607,882 (GRCm39) |
|
probably null |
Het |
| Adgrv1 |
A |
T |
13: 81,672,898 (GRCm39) |
|
probably null |
Het |
| Ak2 |
A |
G |
4: 128,892,976 (GRCm39) |
D45G |
probably damaging |
Het |
| Ak9 |
C |
G |
10: 41,298,403 (GRCm39) |
Q1489E |
unknown |
Het |
| Ak9 |
A |
T |
10: 41,298,404 (GRCm39) |
Q1489L |
unknown |
Het |
| Akap12 |
C |
A |
10: 4,306,268 (GRCm39) |
S1026Y |
possibly damaging |
Het |
| Ankhd1 |
T |
G |
18: 36,744,862 (GRCm39) |
S601A |
possibly damaging |
Het |
| Apba2 |
A |
T |
7: 64,389,628 (GRCm39) |
E508V |
probably damaging |
Het |
| Arhgap18 |
A |
G |
10: 26,722,031 (GRCm39) |
M1V |
probably null |
Het |
| Arhgef10l |
G |
A |
4: 140,270,073 (GRCm39) |
T865M |
possibly damaging |
Het |
| Bdh1 |
T |
A |
16: 31,268,715 (GRCm39) |
V150D |
probably damaging |
Het |
| Becn1 |
A |
G |
11: 101,186,200 (GRCm39) |
C135R |
probably damaging |
Het |
| C2cd4d |
A |
G |
3: 94,271,226 (GRCm39) |
D164G |
probably benign |
Het |
| Cacna1e |
C |
A |
1: 154,362,316 (GRCm39) |
V424F |
possibly damaging |
Het |
| Capn7 |
C |
A |
14: 31,085,560 (GRCm39) |
T511K |
probably benign |
Het |
| Cdc5l |
G |
A |
17: 45,718,943 (GRCm39) |
P558S |
probably benign |
Het |
| Cep170 |
T |
A |
1: 176,609,975 (GRCm39) |
H112L |
probably damaging |
Het |
| Cfap61 |
C |
T |
2: 145,789,053 (GRCm39) |
T19M |
probably benign |
Het |
| Clca3a1 |
A |
G |
3: 144,463,821 (GRCm39) |
V152A |
probably benign |
Het |
| Cnot10 |
G |
T |
9: 114,461,791 (GRCm39) |
T24K |
probably damaging |
Het |
| Cntnap5b |
T |
A |
1: 100,306,800 (GRCm39) |
I839N |
possibly damaging |
Het |
| Cyp4f13 |
A |
T |
17: 33,148,847 (GRCm39) |
D299E |
probably damaging |
Het |
| Dclk1 |
A |
G |
3: 55,395,232 (GRCm39) |
E128G |
probably damaging |
Het |
| Dennd1b |
T |
C |
1: 139,061,413 (GRCm39) |
I365T |
probably damaging |
Het |
| Dgcr8 |
T |
C |
16: 18,102,274 (GRCm39) |
T3A |
probably damaging |
Het |
| Dld |
A |
C |
12: 31,394,847 (GRCm39) |
I58S |
probably damaging |
Het |
| Dlg5 |
T |
A |
14: 24,240,506 (GRCm39) |
R248S |
probably damaging |
Het |
| Eml2 |
G |
A |
7: 18,935,088 (GRCm39) |
V432I |
probably damaging |
Het |
| Faf1 |
C |
T |
4: 109,719,012 (GRCm39) |
L373F |
probably damaging |
Het |
| Fam171b |
C |
T |
2: 83,707,042 (GRCm39) |
T304I |
probably benign |
Het |
| Fcgrt |
A |
T |
7: 44,751,622 (GRCm39) |
|
probably null |
Het |
| Gimap9 |
T |
C |
6: 48,655,285 (GRCm39) |
W291R |
probably damaging |
Het |
| Gm4847 |
G |
A |
1: 166,457,892 (GRCm39) |
A487V |
probably damaging |
Het |
| Gria4 |
T |
A |
9: 4,420,199 (GRCm39) |
I888F |
probably benign |
Het |
| Hapln2 |
T |
A |
3: 87,930,600 (GRCm39) |
I224F |
probably damaging |
Het |
| Herc1 |
T |
G |
9: 66,283,663 (GRCm39) |
L332R |
possibly damaging |
Het |
| Hmgxb4 |
T |
C |
8: 75,749,927 (GRCm39) |
V481A |
probably benign |
Het |
| Htr1d |
T |
C |
4: 136,170,109 (GRCm39) |
S113P |
probably damaging |
Het |
| Ift81 |
T |
C |
5: 122,689,163 (GRCm39) |
Q651R |
probably benign |
Het |
| Il17ra |
T |
C |
6: 120,452,234 (GRCm39) |
S199P |
probably damaging |
Het |
| Itih2 |
T |
C |
2: 10,103,318 (GRCm39) |
N723S |
probably benign |
Het |
| Jak1 |
A |
T |
4: 101,032,325 (GRCm39) |
V427E |
probably damaging |
Het |
| Krt23 |
C |
T |
11: 99,376,584 (GRCm39) |
D191N |
probably damaging |
Het |
| Lingo1 |
T |
A |
9: 56,526,934 (GRCm39) |
I552F |
possibly damaging |
Het |
| Llgl2 |
G |
A |
11: 115,737,812 (GRCm39) |
R199Q |
probably benign |
Het |
| Lrrc37a |
G |
T |
11: 103,392,042 (GRCm39) |
Q1128K |
possibly damaging |
Het |
| Lrrc74a |
T |
C |
12: 86,783,263 (GRCm39) |
V36A |
probably benign |
Het |
| M1ap |
T |
A |
6: 82,980,877 (GRCm39) |
D254E |
possibly damaging |
Het |
| Mal2 |
C |
T |
15: 54,434,794 (GRCm39) |
|
probably benign |
Het |
| Mbnl2 |
A |
G |
14: 120,622,833 (GRCm39) |
T124A |
probably benign |
Het |
| Nfatc1 |
A |
G |
18: 80,755,885 (GRCm39) |
S33P |
probably benign |
Het |
| Nfkbid |
A |
G |
7: 30,125,162 (GRCm39) |
N253S |
probably damaging |
Het |
| Ngfr |
T |
A |
11: 95,465,267 (GRCm39) |
I194F |
probably benign |
Het |
| Nhsl1 |
A |
G |
10: 18,345,789 (GRCm39) |
|
probably benign |
Het |
| Nol9 |
T |
A |
4: 152,125,691 (GRCm39) |
I214N |
possibly damaging |
Het |
| Or1o3 |
A |
G |
17: 37,573,635 (GRCm39) |
S307P |
probably benign |
Het |
| Or5p56 |
T |
C |
7: 107,590,307 (GRCm39) |
L245P |
probably damaging |
Het |
| Or8k3 |
T |
A |
2: 86,058,578 (GRCm39) |
T246S |
possibly damaging |
Het |
| Pax3 |
C |
T |
1: 78,169,186 (GRCm39) |
S160N |
possibly damaging |
Het |
| Pde3b |
A |
G |
7: 114,122,267 (GRCm39) |
|
probably null |
Het |
| Pde5a |
A |
C |
3: 122,522,956 (GRCm39) |
E21A |
probably benign |
Het |
| Plcxd1 |
A |
G |
5: 110,250,469 (GRCm39) |
E270G |
probably damaging |
Het |
| Pramel34 |
A |
T |
5: 93,785,937 (GRCm39) |
N114K |
probably benign |
Het |
| Prb1b |
T |
A |
6: 132,289,692 (GRCm39) |
H44L |
unknown |
Het |
| Psg21 |
G |
T |
7: 18,388,926 (GRCm39) |
D55E |
possibly damaging |
Het |
| Rasa1 |
C |
A |
13: 85,381,814 (GRCm39) |
A493S |
probably benign |
Het |
| Raver2 |
A |
G |
4: 100,990,814 (GRCm39) |
I396V |
probably benign |
Het |
| Rpa2 |
A |
G |
4: 132,502,331 (GRCm39) |
K138E |
probably benign |
Het |
| Rsad1 |
T |
C |
11: 94,439,062 (GRCm39) |
N133D |
probably damaging |
Het |
| Rusc1 |
T |
C |
3: 88,999,188 (GRCm39) |
D198G |
probably benign |
Het |
| Samsn1 |
A |
T |
16: 75,667,803 (GRCm39) |
Y258N |
probably damaging |
Het |
| Scap |
A |
G |
9: 110,203,135 (GRCm39) |
N270D |
probably benign |
Het |
| Shisal2a |
A |
T |
4: 108,225,052 (GRCm39) |
I170N |
probably damaging |
Het |
| Smpd4 |
T |
C |
16: 17,449,877 (GRCm39) |
Y200H |
probably damaging |
Het |
| Steap2 |
A |
G |
5: 5,725,881 (GRCm39) |
V381A |
probably damaging |
Het |
| Syk |
C |
T |
13: 52,765,089 (GRCm39) |
T72I |
probably damaging |
Het |
| Tbc1d14 |
T |
C |
5: 36,729,228 (GRCm39) |
D66G |
possibly damaging |
Het |
| Tcp11 |
A |
G |
17: 28,290,691 (GRCm39) |
Y223H |
probably benign |
Het |
| Timm9 |
A |
G |
12: 71,173,124 (GRCm39) |
S8P |
probably benign |
Het |
| Tmpo |
T |
C |
10: 91,000,069 (GRCm39) |
|
probably null |
Het |
| Vezf1 |
T |
C |
11: 87,967,012 (GRCm39) |
M81T |
probably benign |
Het |
| Vipr1 |
T |
A |
9: 121,493,719 (GRCm39) |
W257R |
probably damaging |
Het |
| Vmn1r237 |
G |
A |
17: 21,534,556 (GRCm39) |
G93D |
probably damaging |
Het |
| Vmn2r6 |
A |
G |
3: 64,445,424 (GRCm39) |
V678A |
probably benign |
Het |
| Vmn2r85 |
T |
C |
10: 130,261,330 (GRCm39) |
T336A |
possibly damaging |
Het |
| Xpnpep3 |
C |
A |
15: 81,322,300 (GRCm39) |
D296E |
probably benign |
Het |
| Zfp35 |
C |
A |
18: 24,137,118 (GRCm39) |
H487Q |
probably benign |
Het |
| Zfp606 |
A |
T |
7: 12,227,928 (GRCm39) |
Y625F |
probably damaging |
Het |
| Zfp677 |
A |
G |
17: 21,617,530 (GRCm39) |
T196A |
possibly damaging |
Het |
| Zmym1 |
T |
C |
4: 126,941,677 (GRCm39) |
I904V |
probably damaging |
Het |
|
| Other mutations in Plxna1 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00427:Plxna1
|
APN |
6 |
89,297,980 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01358:Plxna1
|
APN |
6 |
89,299,732 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01475:Plxna1
|
APN |
6 |
89,331,870 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
IGL01480:Plxna1
|
APN |
6 |
89,321,078 (GRCm39) |
missense |
possibly damaging |
0.70 |
|
IGL01585:Plxna1
|
APN |
6 |
89,306,538 (GRCm39) |
critical splice donor site |
probably null |
|
|
IGL01804:Plxna1
|
APN |
6 |
89,306,628 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01909:Plxna1
|
APN |
6 |
89,309,066 (GRCm39) |
critical splice donor site |
probably null |
|
|
IGL01989:Plxna1
|
APN |
6 |
89,306,396 (GRCm39) |
nonsense |
probably null |
|
|
IGL02015:Plxna1
|
APN |
6 |
89,319,433 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02023:Plxna1
|
APN |
6 |
89,334,314 (GRCm39) |
missense |
possibly damaging |
0.88 |
|
IGL02668:Plxna1
|
APN |
6 |
89,334,251 (GRCm39) |
nonsense |
probably null |
|
|
IGL02703:Plxna1
|
APN |
6 |
89,333,925 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02954:Plxna1
|
APN |
6 |
89,301,649 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03212:Plxna1
|
APN |
6 |
89,308,885 (GRCm39) |
missense |
probably damaging |
1.00 |
|
PIT4544001:Plxna1
|
UTSW |
6 |
89,334,411 (GRCm39) |
missense |
probably benign |
0.14 |
|
R0055:Plxna1
|
UTSW |
6 |
89,306,721 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R0055:Plxna1
|
UTSW |
6 |
89,306,721 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R0147:Plxna1
|
UTSW |
6 |
89,297,692 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R0149:Plxna1
|
UTSW |
6 |
89,297,595 (GRCm39) |
missense |
probably null |
0.95 |
|
R0166:Plxna1
|
UTSW |
6 |
89,310,001 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0200:Plxna1
|
UTSW |
6 |
89,300,575 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0415:Plxna1
|
UTSW |
6 |
89,334,318 (GRCm39) |
missense |
probably benign |
0.12 |
|
R0841:Plxna1
|
UTSW |
6 |
89,309,186 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1018:Plxna1
|
UTSW |
6 |
89,319,942 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1240:Plxna1
|
UTSW |
6 |
89,298,032 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1355:Plxna1
|
UTSW |
6 |
89,297,748 (GRCm39) |
unclassified |
probably benign |
|
|
R1700:Plxna1
|
UTSW |
6 |
89,333,990 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1776:Plxna1
|
UTSW |
6 |
89,312,446 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1957:Plxna1
|
UTSW |
6 |
89,308,273 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2314:Plxna1
|
UTSW |
6 |
89,301,298 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2968:Plxna1
|
UTSW |
6 |
89,319,590 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3118:Plxna1
|
UTSW |
6 |
89,333,958 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R3522:Plxna1
|
UTSW |
6 |
89,314,335 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
R3619:Plxna1
|
UTSW |
6 |
89,334,435 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R3766:Plxna1
|
UTSW |
6 |
89,311,757 (GRCm39) |
unclassified |
probably benign |
|
|
R3847:Plxna1
|
UTSW |
6 |
89,333,501 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3849:Plxna1
|
UTSW |
6 |
89,333,501 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3872:Plxna1
|
UTSW |
6 |
89,309,674 (GRCm39) |
nonsense |
probably null |
|
|
R4555:Plxna1
|
UTSW |
6 |
89,300,310 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R4709:Plxna1
|
UTSW |
6 |
89,311,733 (GRCm39) |
missense |
possibly damaging |
0.72 |
|
R4726:Plxna1
|
UTSW |
6 |
89,299,798 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4739:Plxna1
|
UTSW |
6 |
89,309,657 (GRCm39) |
splice site |
probably null |
|
|
R5053:Plxna1
|
UTSW |
6 |
89,299,442 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5221:Plxna1
|
UTSW |
6 |
89,297,998 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5449:Plxna1
|
UTSW |
6 |
89,300,590 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5480:Plxna1
|
UTSW |
6 |
89,301,616 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5575:Plxna1
|
UTSW |
6 |
89,301,523 (GRCm39) |
missense |
possibly damaging |
0.83 |
|
R5743:Plxna1
|
UTSW |
6 |
89,333,511 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5744:Plxna1
|
UTSW |
6 |
89,311,664 (GRCm39) |
missense |
possibly damaging |
0.67 |
|
R5754:Plxna1
|
UTSW |
6 |
89,310,087 (GRCm39) |
missense |
possibly damaging |
0.96 |
|
R5868:Plxna1
|
UTSW |
6 |
89,299,704 (GRCm39) |
splice site |
probably benign |
|
|
R5988:Plxna1
|
UTSW |
6 |
89,334,522 (GRCm39) |
nonsense |
probably null |
|
|
R6425:Plxna1
|
UTSW |
6 |
89,311,647 (GRCm39) |
missense |
probably benign |
0.00 |
|
R6561:Plxna1
|
UTSW |
6 |
89,333,960 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6623:Plxna1
|
UTSW |
6 |
89,299,753 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6638:Plxna1
|
UTSW |
6 |
89,301,382 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R6701:Plxna1
|
UTSW |
6 |
89,296,430 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R6825:Plxna1
|
UTSW |
6 |
89,297,597 (GRCm39) |
missense |
probably benign |
0.01 |
|
R6911:Plxna1
|
UTSW |
6 |
89,297,956 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7073:Plxna1
|
UTSW |
6 |
89,334,311 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7177:Plxna1
|
UTSW |
6 |
89,300,311 (GRCm39) |
missense |
possibly damaging |
0.50 |
|
R7235:Plxna1
|
UTSW |
6 |
89,317,573 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R7419:Plxna1
|
UTSW |
6 |
89,334,584 (GRCm39) |
missense |
unknown |
|
|
R7511:Plxna1
|
UTSW |
6 |
89,318,889 (GRCm39) |
missense |
possibly damaging |
0.71 |
|
R7543:Plxna1
|
UTSW |
6 |
89,299,837 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7665:Plxna1
|
UTSW |
6 |
89,301,520 (GRCm39) |
critical splice donor site |
probably null |
|
|
R7678:Plxna1
|
UTSW |
6 |
89,308,882 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7748:Plxna1
|
UTSW |
6 |
89,314,335 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
R7748:Plxna1
|
UTSW |
6 |
89,314,334 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
R7877:Plxna1
|
UTSW |
6 |
89,300,241 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R8025:Plxna1
|
UTSW |
6 |
89,308,254 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8171:Plxna1
|
UTSW |
6 |
89,334,102 (GRCm39) |
missense |
probably benign |
0.20 |
|
R8277:Plxna1
|
UTSW |
6 |
89,334,162 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8782:Plxna1
|
UTSW |
6 |
89,300,220 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8867:Plxna1
|
UTSW |
6 |
89,310,079 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9245:Plxna1
|
UTSW |
6 |
89,314,320 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9253:Plxna1
|
UTSW |
6 |
89,334,522 (GRCm39) |
nonsense |
probably null |
|
|
R9269:Plxna1
|
UTSW |
6 |
89,306,541 (GRCm39) |
missense |
probably null |
1.00 |
|
R9273:Plxna1
|
UTSW |
6 |
89,296,364 (GRCm39) |
missense |
possibly damaging |
0.77 |
|
R9281:Plxna1
|
UTSW |
6 |
89,300,313 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9368:Plxna1
|
UTSW |
6 |
89,314,138 (GRCm39) |
missense |
probably benign |
|
|
R9440:Plxna1
|
UTSW |
6 |
89,318,912 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9526:Plxna1
|
UTSW |
6 |
89,319,633 (GRCm39) |
missense |
probably benign |
|
|
R9601:Plxna1
|
UTSW |
6 |
89,308,253 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9714:Plxna1
|
UTSW |
6 |
89,296,440 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R9782:Plxna1
|
UTSW |
6 |
89,333,817 (GRCm39) |
missense |
probably benign |
0.01 |
|
S24628:Plxna1
|
UTSW |
6 |
89,334,318 (GRCm39) |
missense |
probably benign |
0.12 |
|
V8831:Plxna1
|
UTSW |
6 |
89,334,119 (GRCm39) |
missense |
probably damaging |
0.99 |
|
Z1176:Plxna1
|
UTSW |
6 |
89,298,034 (GRCm39) |
missense |
probably damaging |
1.00 |
|
| Predicted Primers |
PCR Primer
(F):5'- AGGTGAAATGTGACCCCAGG -3'
(R):5'- CGTGAATGACCCCAAGTTCTAC -3'
Sequencing Primer
(F):5'- CCAGGAAGGGTGGCGGG -3'
(R):5'- CCAAGTTCTACTCTTACGTGGAG -3'
|
| Posted On |
2018-02-27 |
Incidental Mutation